Temat: "Injections, Intraperitoneal" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Intraperitoneal Injection of MCC950 Inhibits the Progression of Myopia in Form-Deprivation Myopic Mice.
Autorzy:: Chen Z; Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.; Key Laboratory of Ocular Fundus Diseases, Chinese Academy of Medical Sciences, Beijing 100730, China.
Xiao K; Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.; Key Laboratory of Ocular Fundus Diseases, Chinese Academy of Medical Sciences, Beijing 100730, China.
Long Q; Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.; Key Laboratory of Ocular Fundus Diseases, Chinese Academy of Medical Sciences, Beijing 100730, China.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Oct 31; Vol. 24 (21). Date of Electronic Publication: 2023 Oct 31.
Typ publikacji:: Journal Article
MeSH Terms:: Matrix Metalloproteinase 2*/genetics
Matrix Metalloproteinase 2*/metabolism
Myopia*/drug therapy
Myopia*/metabolism
Animals ; Mice ; Humans ; Interleukin-18/metabolism ; Injections, Intraperitoneal ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; Mice, Inbred C57BL ; Sclera/metabolism ; Collagen/metabolism ; Collagen Type I/metabolism ; Caspases/metabolism ; Disease Models, Animal

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Skocz do pozycji: 2.

Tytuł:: Effects of chronic cirrhosis induced by intraperitoneal thioacetamide injection on the protein content and Michaelis-Menten kinetics of cytochrome P450 enzymes in the rat liver microsomes.
Autorzy:: Chandrashekar DV; Department of Biomedical and Pharmaceutical Sciences, School of Pharmacy, Chapman University, Irvine, California, USA.
DuBois BN; Department of Biomedical and Pharmaceutical Sciences, School of Pharmacy, Chapman University, Irvine, California, USA.
Rashid M; Department of Biomedical and Pharmaceutical Sciences, School of Pharmacy, Chapman University, Irvine, California, USA.
Mehvar R; Department of Biomedical and Pharmaceutical Sciences, School of Pharmacy, Chapman University, Irvine, California, USA.; Pokaż więcej
Źródło:: Basic & clinical pharmacology & toxicology [Basic Clin Pharmacol Toxicol] 2023 Feb; Vol. 132 (2), pp. 197-210. Date of Electronic Publication: 2022 Nov 24.
Typ publikacji:: Journal Article
MeSH Terms:: Cytochrome P-450 CYP2E1*/metabolism
Aryl Hydrocarbon Hydroxylases*
Humans ; Rats ; Animals ; Microsomes, Liver ; Thioacetamide/toxicity ; Cytochrome P-450 CYP3A/metabolism ; Injections, Intraperitoneal ; Cytochrome P-450 Enzyme System/metabolism ; Liver Cirrhosis/metabolism ; Liver ; Fibrosis

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Skocz do pozycji: 3.

Tytuł:: Saroglitazar suppresses the hepatocellular carcinoma induced by intraperitoneal injection of diethylnitrosamine in C57BL/6 mice fed on choline deficient, l-amino acid- defined, high-fat diet.
Autorzy:: Giri SR; Department of Pharmacology and Toxicology, Zydus Research Centre, Zydus Lifesciences Limited (formerly known as Cadila Healthcare Limited), Sarkhej-Bavla N.H.No. 8A, Moraiya, Ahmedabad, Gujarat, 382213, India. .
Bhoi B; Department of Pharmacology and Toxicology, Zydus Research Centre, Zydus Lifesciences Limited (formerly known as Cadila Healthcare Limited), Sarkhej-Bavla N.H.No. 8A, Moraiya, Ahmedabad, Gujarat, 382213, India.
Trivedi C; Department of Pharmacology and Toxicology, Zydus Research Centre, Zydus Lifesciences Limited (formerly known as Cadila Healthcare Limited), Sarkhej-Bavla N.H.No. 8A, Moraiya, Ahmedabad, Gujarat, 382213, India.
Rath A; Department of Pharmacology and Toxicology, Zydus Research Centre, Zydus Lifesciences Limited (formerly known as Cadila Healthcare Limited), Sarkhej-Bavla N.H.No. 8A, Moraiya, Ahmedabad, Gujarat, 382213, India.
Rathod R; Department of Pharmacology and Toxicology, Zydus Research Centre, Zydus Lifesciences Limited (formerly known as Cadila Healthcare Limited), Sarkhej-Bavla N.H.No. 8A, Moraiya, Ahmedabad, Gujarat, 382213, India.
Sharma A; Department of Pharmacology and Toxicology, Zydus Research Centre, Zydus Lifesciences Limited (formerly known as Cadila Healthcare Limited), Sarkhej-Bavla N.H.No. 8A, Moraiya, Ahmedabad, Gujarat, 382213, India.
Ranvir R; Department of Pharmacology and Toxicology, Zydus Research Centre, Zydus Lifesciences Limited (formerly known as Cadila Healthcare Limited), Sarkhej-Bavla N.H.No. 8A, Moraiya, Ahmedabad, Gujarat, 382213, India.
Kadam S; Department of Pharmacology and Toxicology, Zydus Research Centre, Zydus Lifesciences Limited (formerly known as Cadila Healthcare Limited), Sarkhej-Bavla N.H.No. 8A, Moraiya, Ahmedabad, Gujarat, 382213, India.
Ingale K; Department of Pharmacology and Toxicology, Zydus Research Centre, Zydus Lifesciences Limited (formerly known as Cadila Healthcare Limited), Sarkhej-Bavla N.H.No. 8A, Moraiya, Ahmedabad, Gujarat, 382213, India.
Patel H; Department of Pharmacology and Toxicology, Zydus Research Centre, Zydus Lifesciences Limited (formerly known as Cadila Healthcare Limited), Sarkhej-Bavla N.H.No. 8A, Moraiya, Ahmedabad, Gujarat, 382213, India.
Nyska A; Tel Aviv University, Yehuda HaMaccabi 31, floor 5, 6200515, Tel Aviv, Israel.
Jain MR; Department of Pharmacology and Toxicology, Zydus Research Centre, Zydus Lifesciences Limited (formerly known as Cadila Healthcare Limited), Sarkhej-Bavla N.H.No. 8A, Moraiya, Ahmedabad, Gujarat, 382213, India.; Pokaż więcej
Źródło:: BMC cancer [BMC Cancer] 2023 Jan 17; Vol. 23 (1), pp. 59. Date of Electronic Publication: 2023 Jan 17.
Typ publikacji:: Journal Article
MeSH Terms:: Carcinoma, Hepatocellular*/chemically induced
Carcinoma, Hepatocellular*/drug therapy
Carcinoma, Hepatocellular*/prevention & control
Liver Neoplasms*/chemically induced
Liver Neoplasms*/drug therapy
Liver Neoplasms*/prevention & control
Non-alcoholic Fatty Liver Disease*/etiology
Mice ; Animals ; Choline ; Diethylnitrosamine/toxicity ; Injections, Intraperitoneal ; Diet, High-Fat/adverse effects ; Amino Acids ; Peroxisome Proliferator-Activated Receptors ; Mice, Inbred C57BL ; Liver/pathology ; Disease Models, Animal

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Skocz do pozycji: 4.

Tytuł:: Development of a non-invasive method for testicular toxicity evaluation using a novel compact magnetic resonance imaging system.
Autorzy:: Yokota S; Division of Cellular & Molecular Toxicology, Center for Biological Safety & Research, National Institute of Health Sciences.
Miyaso H; Department of Anatomy, Faculty of Medicine, School of Medicine, International University of Health and Welfare.
Hirai T; Department of Diagnostic Radiology, Graduate School of Medical Sciences, Kumamoto University.
Suga K; Division of Cellular & Molecular Toxicology, Center for Biological Safety & Research, National Institute of Health Sciences.
Wakayama T; Department of Histology, Graduate School of Medical Sciences, Kumamoto University.
Taquahashi Y; Division of Cellular & Molecular Toxicology, Center for Biological Safety & Research, National Institute of Health Sciences.
Kitajima S; Division of Cellular & Molecular Toxicology, Center for Biological Safety & Research, National Institute of Health Sciences.; Pokaż więcej
Źródło:: The Journal of toxicological sciences [J Toxicol Sci] 2023; Vol. 48 (2), pp. 57-64.
Typ publikacji:: Journal Article
MeSH Terms:: Testis*/diagnostic imaging
Spermatogenesis*
Male ; Mice ; Animals ; Busulfan/toxicity ; Injections, Intraperitoneal ; Magnetic Resonance Imaging

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Skocz do pozycji: 5.

Tytuł:: Influence of pneumoperitoneum and head-down maneuver on the cerebral microvasculature in rabbits.
Autorzy:: Kobayashi H; Department of Anesthesiology, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan.
Asano N; Department of Anesthesiology, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan.
Kondo D; Department of Anesthesiology, Yamanashi Prefectural Central Hospital, 1-1-1 Fujimi, Kofu, Yamanashi, 400-8506, Japan.
Shintani N; Department of Anesthesiology, Kofu Municipal Hospital, 366 Masutsubo, Kofu, Yamanashi, 400-0832, Japan.
Kotoda M; Department of Anesthesiology, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan. .
Matsuoka T; Department of Anesthesiology, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan.
Ishiyama T; Surgical Center, University of Yamanashi Hospital, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan.
Matsukawa T; Department of Anesthesiology, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan.; Pokaż więcej
Źródło:: BMC anesthesiology [BMC Anesthesiol] 2022 Dec 01; Vol. 22 (1), pp. 370. Date of Electronic Publication: 2022 Dec 01.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Pneumoperitoneum*
Brain Edema*
Male ; Animals ; Rabbits ; Injections, Intraperitoneal ; Microvessels ; Microcirculation

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Skocz do pozycji: 6.

Tytuł:: Synthesis and Evaluation of NF-κB Inhibitory Activity of Mollugin Derivatives.
Autorzy:: Zhang LH; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji 133000, China.
Li MY; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji 133000, China.
Wang DY; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji 133000, China.
Jin XJ; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji 133000, China.
Chen FE; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji 133000, China.; Engineering Center of Catalysis and Synthesis for Chiral Molecules, Department of Chemistry, Fudan University, Shanghai 200433, China.
Piao HR; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji 133000, China.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2022 Nov 16; Vol. 27 (22). Date of Electronic Publication: 2022 Nov 16.
Typ publikacji:: Journal Article
MeSH Terms:: NF-kappa B*
Pyrans*
Humans ; Inflammation ; Injections, Intraperitoneal

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Skocz do pozycji: 7.

Tytuł:: Treatment of rats with spinal cord injury using human bone marrow-derived stromal cells prepared by negative selection.
Autorzy:: Romero-Ramírez L; Hospital Nacional de Parapléjicos, c/Finca la Peraleda, 45071, Toledo, Spain.
Wu S; Hospital Nacional de Parapléjicos, c/Finca la Peraleda, 45071, Toledo, Spain.; School of Mental Health and Neuroscience and EURON Graduate School of Neuroscience, Maastricht University, Universiteitssingel 40, 6229ER, Maastricht, Netherlands.
de Munter J; Neuroplast BV, Urmonderbaan 22, 6167RD, Geleen, Netherlands.
Wolters EC; Neuroplast BV, Urmonderbaan 22, 6167RD, Geleen, Netherlands.
Kramer BW; School of Mental Health and Neuroscience and EURON Graduate School of Neuroscience, Maastricht University, Universiteitssingel 40, 6229ER, Maastricht, Netherlands.
Mey J; Hospital Nacional de Parapléjicos, c/Finca la Peraleda, 45071, Toledo, Spain. .; School of Mental Health and Neuroscience and EURON Graduate School of Neuroscience, Maastricht University, Universiteitssingel 40, 6229ER, Maastricht, Netherlands. .; Pokaż więcej
Źródło:: Journal of biomedical science [J Biomed Sci] 2020 Feb 18; Vol. 27 (1), pp. 35. Date of Electronic Publication: 2020 Feb 18.
Typ publikacji:: Comparative Study; Journal Article
MeSH Terms:: Injections, Intraperitoneal*
Injections, Spinal*
Inflammation/*prevention & control
Mesenchymal Stem Cell Transplantation/*instrumentation
Nerve Regeneration/*physiology
Spinal Cord Injuries/*therapy
Humans ; Mesenchymal Stem Cells/physiology

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Skocz do pozycji: 8.

Tytuł:: Effects of intraperitoneal injection of lipopolysaccharide-induced peripheral inflammation on dopamine neuron damage in rat midbrain.
Autorzy:: Yang QY; Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education and Key Laboratory of Basic Pharmacology of Guizhou Province and Laboratory Animal Center, Zunyi Medical University, Zunyi, China.
Li XW; Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education and Key Laboratory of Basic Pharmacology of Guizhou Province and Laboratory Animal Center, Zunyi Medical University, Zunyi, China.
Yang R; Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education and Key Laboratory of Basic Pharmacology of Guizhou Province and Laboratory Animal Center, Zunyi Medical University, Zunyi, China.
Qin TY; Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education and Key Laboratory of Basic Pharmacology of Guizhou Province and Laboratory Animal Center, Zunyi Medical University, Zunyi, China.
Long H; Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education and Key Laboratory of Basic Pharmacology of Guizhou Province and Laboratory Animal Center, Zunyi Medical University, Zunyi, China.
Zhang SB; Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education and Key Laboratory of Basic Pharmacology of Guizhou Province and Laboratory Animal Center, Zunyi Medical University, Zunyi, China.
Zhang F; Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education and Key Laboratory of Basic Pharmacology of Guizhou Province and Laboratory Animal Center, Zunyi Medical University, Zunyi, China.; Pokaż więcej
Źródło:: CNS neuroscience & therapeutics [CNS Neurosci Ther] 2022 Oct; Vol. 28 (10), pp. 1624-1636. Date of Electronic Publication: 2022 Jul 04.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Dopaminergic Neurons*
Lipopolysaccharides*/toxicity
Animals ; Biomarkers/metabolism ; Inflammation/metabolism ; Injections, Intraperitoneal ; Mesencephalon/metabolism ; Microglia ; RNA, Messenger/metabolism ; Rats ; Substantia Nigra

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Skocz do pozycji: 9.

Tytuł:: Chronic intraperitoneal injection of polyethylene glycol 200 in mice induces hippocampal neuroinflammation.
Autorzy:: Freyssin A; EA3808 Neurovascular Unit and Cognitive Disorders, Pôle Biologie Santé, University of Poitiers, Poitiers, France.
Fauconneau B; EA3808 Neurovascular Unit and Cognitive Disorders, Pôle Biologie Santé, University of Poitiers, Poitiers, France.
Chassaing D; EA3808 Neurovascular Unit and Cognitive Disorders, Pôle Biologie Santé, University of Poitiers, Poitiers, France.
Rioux Bilan A; EA3808 Neurovascular Unit and Cognitive Disorders, Pôle Biologie Santé, University of Poitiers, Poitiers, France.
Page G; EA3808 Neurovascular Unit and Cognitive Disorders, Pôle Biologie Santé, University of Poitiers, Poitiers, France.; Pokaż więcej
Źródło:: Drug and chemical toxicology [Drug Chem Toxicol] 2022 Sep; Vol. 45 (5), pp. 1995-2002. Date of Electronic Publication: 2021 Mar 10.
Typ publikacji:: Journal Article
MeSH Terms:: Hippocampus*
Neuroinflammatory Diseases*
Animals ; Astrocytes/metabolism ; Glial Fibrillary Acidic Protein/metabolism ; Glial Fibrillary Acidic Protein/pharmacology ; Injections, Intraperitoneal ; Mice ; Microglia ; Polyethylene Glycols/toxicity

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Skocz do pozycji: 10.

Tytuł:: A model-specific simplification of the Mouse Grimace Scale based on the pain response of intraperitoneal CCl 4 injections.
Autorzy:: Ernst L; Faculty of Medicine, Institute for Laboratory Animal Science and Experimental Surgery, RWTH Aachen University, Aachen, Germany.
Bruch S; Faculty of Medicine, Institute for Laboratory Animal Science and Experimental Surgery, RWTH Aachen University, Aachen, Germany.
Kopaczka M; Institute of Imaging and Computer Vision, RWTH Aachen University, Aachen, Germany.
Merhof D; Institute of Imaging and Computer Vision, RWTH Aachen University, Aachen, Germany.
Bleich A; Institute for Laboratory Animal Science, Hannover Medical School, Hanover, Germany.
Tolba RH; Faculty of Medicine, Institute for Laboratory Animal Science and Experimental Surgery, RWTH Aachen University, Aachen, Germany. .
Talbot SR; Institute for Laboratory Animal Science, Hannover Medical School, Hanover, Germany.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2022 Jun 28; Vol. 12 (1), pp. 10910. Date of Electronic Publication: 2022 Jun 28.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Acute Pain*
Facial Expression*
Animals ; Injections, Intraperitoneal ; Male ; Mice ; Mice, Inbred C57BL ; Pain Measurement/methods

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Skocz do pozycji: 11.

Tytuł:: Does memantine show chemopreventive effect against mice 4T1 breast tumor model?
Autorzy:: Albayrak G; Department of Medical Biology, Faculty of Medicine, Ufuk University, Ankara, Turkey.
Bali EB; Department of Medical Services and Techniques, Vocational School of Health Services, Gazi University, Ankara, Turkey.
Korkmaz FD; Department of Medical Biology, Faculty of Medicine, Giresun University, Ankara, Turkey.
Bağrıaçık EÜ; Department of Immunology, Faculty of Medicine, Gazi University, Ankara, Turkey.; Pokaż więcej
Źródło:: Turkish journal of medical sciences [Turk J Med Sci] 2022 Jun; Vol. 52 (3), pp. 841-847. Date of Electronic Publication: 2022 Jun 16.
Typ publikacji:: Journal Article
MeSH Terms:: Memantine*/pharmacology
Interleukin-6*
Animals ; Female ; Mice ; Mice, Inbred BALB C ; Disease Models, Animal ; Injections, Intraperitoneal

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Skocz do pozycji: 12.

Tytuł:: Effects of fatty acid metabolites on nocturia.
Autorzy:: Ihara T; Department of Urology, Interdisciplinary Graduate School of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan. .
Shimura H; Department of Urology, Interdisciplinary Graduate School of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan.
Tsuchiya S; Department of Urology, Interdisciplinary Graduate School of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan.
Kanda M; Department of Urology, Interdisciplinary Graduate School of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan.
Kira S; Department of Urology, Interdisciplinary Graduate School of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan.
Sawada N; Department of Urology, Interdisciplinary Graduate School of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan.
Takeda M; Department of Urology, Interdisciplinary Graduate School of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan.
Mitsui T; Department of Urology, Interdisciplinary Graduate School of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan.
Shigetomi E; Department of Neuropharmacology, Interdisciplinary Graduate School of Medicine, University of Yamanashi, Chuo, Yamanashi, Japan.
Shinozaki Y; Department of Neuropharmacology, Interdisciplinary Graduate School of Medicine, University of Yamanashi, Chuo, Yamanashi, Japan.
Koizumi S; Department of Neuropharmacology, Interdisciplinary Graduate School of Medicine, University of Yamanashi, Chuo, Yamanashi, Japan.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2022 Feb 23; Vol. 12 (1), pp. 3050. Date of Electronic Publication: 2022 Feb 23.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Fatty Acids/*metabolism
Nocturia/*genetics
Nocturia/*metabolism
Amides/administration & dosage ; Amides/blood ; Animals ; CLOCK Proteins/genetics ; Circadian Rhythm ; Disease Models, Animal ; Docosahexaenoic Acids/administration & dosage ; Docosahexaenoic Acids/blood ; Ethanolamines/administration & dosage ; Ethanolamines/blood ; Fatty Acids/administration & dosage ; Injections, Intraperitoneal ; Linoleic Acids, Conjugated/administration & dosage ; Linoleic Acids, Conjugated/blood ; Male ; Mice, Inbred C57BL ; Nocturia/blood ; Palmitic Acids/administration & dosage ; Palmitic Acids/blood ; Photoperiod ; Urinary Bladder/pathology ; Urination/genetics ; Mice

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Skocz do pozycji: 13.

Tytuł:: Nifuroxazide ameliorates pulmonary fibrosis by blocking myofibroblast genesis: a drug repurposing study.
Autorzy:: Gan C; Sichuan University-Oxford University Huaxi Gastrointestinal Cancer Centre, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, 17# 3rd Section, Ren Min South Road, Chengdu, 610041, China.
Zhang Q; Department of Nutrition and Food Hygiene, School of Public Health, West China Medical School, Sichuan University, Chengdu, 610041, China.
Liu H; Sichuan University-Oxford University Huaxi Gastrointestinal Cancer Centre, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, 17# 3rd Section, Ren Min South Road, Chengdu, 610041, China.
Wang G; Sichuan University-Oxford University Huaxi Gastrointestinal Cancer Centre, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, 17# 3rd Section, Ren Min South Road, Chengdu, 610041, China.; Innovation Center of Nursing Research, West China Hospital, Sichuan University, Chengdu, 610041, China.; Nursing Key Laboratory of Sichuan Province, Sichuan University, Chengdu, 610041, China.
Wang L; Department of Nutrition and Food Hygiene, School of Public Health, West China Medical School, Sichuan University, Chengdu, 610041, China.
Li Y; Department of Nutrition and Food Hygiene, School of Public Health, West China Medical School, Sichuan University, Chengdu, 610041, China.
Tan Z; Sichuan University-Oxford University Huaxi Gastrointestinal Cancer Centre, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, 17# 3rd Section, Ren Min South Road, Chengdu, 610041, China.
Yin W; Department of Nutrition and Food Hygiene, School of Public Health, West China Medical School, Sichuan University, Chengdu, 610041, China.
Yao Y; Department of Nutrition and Food Hygiene, School of Public Health, West China Medical School, Sichuan University, Chengdu, 610041, China.
Xie Y; Sichuan University-Oxford University Huaxi Gastrointestinal Cancer Centre, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, 17# 3rd Section, Ren Min South Road, Chengdu, 610041, China.
Ouyang L; Sichuan University-Oxford University Huaxi Gastrointestinal Cancer Centre, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, 17# 3rd Section, Ren Min South Road, Chengdu, 610041, China.
Yu L; Sichuan University-Oxford University Huaxi Gastrointestinal Cancer Centre, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, 17# 3rd Section, Ren Min South Road, Chengdu, 610041, China.
Ye T; Sichuan University-Oxford University Huaxi Gastrointestinal Cancer Centre, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, 17# 3rd Section, Ren Min South Road, Chengdu, 610041, China. .; Pokaż więcej
Źródło:: Respiratory research [Respir Res] 2022 Feb 16; Vol. 23 (1), pp. 32. Date of Electronic Publication: 2022 Feb 16.
Typ publikacji:: Journal Article
MeSH Terms:: Hydroxybenzoates/*administration & dosage
Idiopathic Pulmonary Fibrosis/*drug therapy
Myofibroblasts/*pathology
Nitrofurans/*administration & dosage
A549 Cells ; Animals ; Anti-Infective Agents/administration & dosage ; Disease Models, Animal ; Drug Repositioning ; Epithelial-Mesenchymal Transition ; Flow Cytometry ; Humans ; Idiopathic Pulmonary Fibrosis/metabolism ; Idiopathic Pulmonary Fibrosis/pathology ; Injections, Intraperitoneal ; Male ; Mice ; Mice, Inbred C57BL ; Myofibroblasts/drug effects ; Myofibroblasts/metabolism ; Rats ; Rats, Wistar ; Signal Transduction

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Skocz do pozycji: 14.

Tytuł:: The Anxiolytic Drug Buspirone Prevents Rotenone-Induced Toxicity in a Mouse Model of Parkinson's Disease.
Autorzy:: Thomas Broome S; Laboratory of Cellular and Molecular Neuroscience (LCMN), School of Life Sciences, Faculty of Science, University of Technology Sydney, Sydney, NSW 2007, Australia.
Castorina A; Laboratory of Cellular and Molecular Neuroscience (LCMN), School of Life Sciences, Faculty of Science, University of Technology Sydney, Sydney, NSW 2007, Australia.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2022 Feb 06; Vol. 23 (3). Date of Electronic Publication: 2022 Feb 06.
Typ publikacji:: Journal Article
MeSH Terms:: Buspirone/*administration & dosage
Neuroprotective Agents/*administration & dosage
Parkinson Disease/*drug therapy
Pituitary Adenylate Cyclase-Activating Polypeptide/*metabolism
Rotenone/*toxicity
Vasoactive Intestinal Peptide/*metabolism
Animals ; Buspirone/pharmacology ; Disease Models, Animal ; Dose-Response Relationship, Drug ; Gene Expression Regulation/drug effects ; Injections, Intraperitoneal ; Interleukin-1beta/genetics ; Interleukin-1beta/metabolism ; Interleukin-6/genetics ; Interleukin-6/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Neuroprotective Agents/pharmacology ; Parkinson Disease/etiology ; Parkinson Disease/genetics ; Parkinson Disease/psychology ; Pituitary Adenylate Cyclase-Activating Polypeptide/genetics ; Vasoactive Intestinal Peptide/genetics

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Skocz do pozycji: 15.

Tytuł:: The bioavailability time of commonly used thymidine analogues after intraperitoneal delivery in mice: labeling kinetics in vivo and clearance from blood serum.
Autorzy:: Maltsev DI; Federal Center of Brain Research and Neurotechnologies, Federal Medical Biological Agency, Moscow, Russia, 117997.; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia, 117997.
Mellanson KA; Molecular and Cellular Pharmacology Graduate Program and Center for Developmental Genetics, Stony Brook University, Stony Brook, NY, 11794, USA.
Belousov VV; Federal Center of Brain Research and Neurotechnologies, Federal Medical Biological Agency, Moscow, Russia, 117997.; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia, 117997.; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Pirogov Russian National Research Medical University, Moscow, Russia, 117997.
Enikolopov GN; Center for Developmental Genetics and Department of Anesthesiology, Stony Brook University, Stony Brook, NY, 11794, USA.; Institute for Advanced Brain Studies, Lomonosov Moscow State University, Moscow, Russia, 119991.
Podgorny OV; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia, 117997. .; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Pirogov Russian National Research Medical University, Moscow, Russia, 117997. .; Koltzov Institute of Developmental Biology, Russian Academy of Sciences, Moscow, Russia, 119334. .; Pokaż więcej
Źródło:: Histochemistry and cell biology [Histochem Cell Biol] 2022 Feb; Vol. 157 (2), pp. 239-250. Date of Electronic Publication: 2021 Nov 10.
Typ publikacji:: Journal Article
MeSH Terms:: Bromodeoxyuridine/*metabolism
Deoxyuridine/*analogs & derivatives
Glyburide/*analogs & derivatives
Thymidine/*metabolism
Animals ; Biological Availability ; Bromodeoxyuridine/administration & dosage ; Bromodeoxyuridine/blood ; Dentate Gyrus/metabolism ; Deoxyuridine/administration & dosage ; Deoxyuridine/blood ; Deoxyuridine/metabolism ; Glyburide/administration & dosage ; Glyburide/blood ; Glyburide/metabolism ; Injections, Intraperitoneal ; Kinetics ; Mice ; Mice, Inbred C57BL ; Thymidine/administration & dosage ; Thymidine/analogs & derivatives

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Skocz do pozycji: 16.

Tytuł:: Development of a rat capnoperitoneum phantom to study drug aerosol deposition in the context of anticancer research on peritoneal carcinomatosis.
Autorzy:: Göhler D; Research Group Mechanical Process Engineering, Institute of Process Engineering and Environmental Technology, Technische Universität Dresden, 01062, Dresden, Germany.; Topas GmbH, 01237, Dresden, Germany.
Geldner A; Research Group Mechanical Process Engineering, Institute of Process Engineering and Environmental Technology, Technische Universität Dresden, 01062, Dresden, Germany. .; Process Systems Engineering Group, Institute of Process Engineering and Environmental Technology, Technische Universität Dresden, 01062, Dresden, Germany. .
Gritzki R; Chair of Building Energy Systems and Heat Supply, Institute of Power Engineering, Technische Universität Dresden, 01062, Dresden, Germany.
Lohse F; Research Group Mechanical Process Engineering, Institute of Process Engineering and Environmental Technology, Technische Universität Dresden, 01062, Dresden, Germany.
Große S; Topas GmbH, 01237, Dresden, Germany.
Sobilo J; CNRS, TAAM UPS44, In Vivo Imaging Centre for Preclinical and Translational Research CIPA, 45071, Orléans, France.
Felsmann C; Chair of Building Energy Systems and Heat Supply, Institute of Power Engineering, Technische Universität Dresden, 01062, Dresden, Germany.
Buggisch JR; CNRS, TAAM UPS44, In Vivo Imaging Centre for Preclinical and Translational Research CIPA, 45071, Orléans, France.; Department of General-, Visceral- and Transplant Surgery, Universität Münster, Münster, Germany.
Le Pape A; CNRS, TAAM UPS44, In Vivo Imaging Centre for Preclinical and Translational Research CIPA, 45071, Orléans, France.
Rudolph A; Topas GmbH, 01237, Dresden, Germany.
Stintz M; Research Group Mechanical Process Engineering, Institute of Process Engineering and Environmental Technology, Technische Universität Dresden, 01062, Dresden, Germany.
Giger-Pabst U; Department of General-, Visceral- and Transplant Surgery, Universität Münster, Münster, Germany.; Surgical Clinic I, Mathias-Spital Rheine, 48431, Rheine, Germany.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 Nov 08; Vol. 11 (1), pp. 21843. Date of Electronic Publication: 2021 Nov 08.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Antineoplastic Agents/*administration & dosage
Peritoneal Neoplasms/*drug therapy
Peritoneum/*diagnostic imaging
Aerosols ; Animals ; Antineoplastic Agents/pharmacokinetics ; Computer Simulation ; Computer-Aided Design ; Humans ; Hydrodynamics ; Injections, Intraperitoneal/instrumentation ; Injections, Intraperitoneal/methods ; Models, Animal ; Peritoneal Neoplasms/diagnostic imaging ; Peritoneal Neoplasms/metabolism ; Peritoneum/metabolism ; Phantoms, Imaging ; Pressure ; Rats ; Tomography, X-Ray Computed ; User-Computer Interface

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Tytuł:: Short communication: Tissue distribution of major cannabinoids following intraperitoneal injection in male rats.
Autorzy:: Lust CAC; Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, ON, Canada.
Lin X; Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, ON, Canada.
Rock EM; Department of Psychology and Collaborative Neuroscience Program, University of Guelph, Guelph, ON, Canada.
Limebeer CL; Department of Psychology and Collaborative Neuroscience Program, University of Guelph, Guelph, ON, Canada.
Parker LA; Department of Psychology and Collaborative Neuroscience Program, University of Guelph, Guelph, ON, Canada.
Ma DWL; Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, ON, Canada.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2022 Jan 19; Vol. 17 (1), pp. e0262633. Date of Electronic Publication: 2022 Jan 19 (Print Publication: 2022).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cannabinoids/*administration & dosage
Cannabinoids/*pharmacology
Tissue Distribution/*physiology
Animals ; Cannabinoids/metabolism ; Injections, Intraperitoneal ; Male ; Pilot Projects ; Rats ; Rats, Sprague-Dawley ; Tissue Distribution/drug effects

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Skocz do pozycji: 18.

Tytuł:: The Effect of TGF-β1 Reduced Functionality on the Expression of Selected Synaptic Proteins and Electrophysiological Parameters: Implications of Changes Observed in Acute Hepatic Encephalopathy.
Autorzy:: Popek M; Department of Neurotoxicology, Mossakowski Medical Research Institute, Polish Academy of Sciences, 5 Pawińskiego Str., 02-106 Warsaw, Poland.
Bobula B; Department of Physiology, Maj Institute of Pharmacology, Polish Academy of Sciences, 12 Smętna Str., 31-343 Krakow, Poland.
Orzeł-Gajowik K; Department of Neurotoxicology, Mossakowski Medical Research Institute, Polish Academy of Sciences, 5 Pawińskiego Str., 02-106 Warsaw, Poland.
Zielińska M; Department of Neurotoxicology, Mossakowski Medical Research Institute, Polish Academy of Sciences, 5 Pawińskiego Str., 02-106 Warsaw, Poland.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2022 Jan 19; Vol. 23 (3). Date of Electronic Publication: 2022 Jan 19.
Typ publikacji:: Journal Article
MeSH Terms:: Azoxymethane/*adverse effects
Brain/*physiopathology
Hepatic Encephalopathy/*physiopathology
Liver Failure, Acute/*metabolism
Transforming Growth Factor beta1/*metabolism
Animals ; Antibodies/administration & dosage ; Antibodies/pharmacology ; Blood-Brain Barrier/metabolism ; Cell Line ; Disease Models, Animal ; Down-Regulation ; Electrophysiological Phenomena ; Hepatic Encephalopathy/chemically induced ; Hepatic Encephalopathy/metabolism ; Injections, Intraperitoneal ; Liver Failure, Acute/chemically induced ; Liver Failure, Acute/physiopathology ; Male ; Mice ; Rats ; Synaptophysin/metabolism ; Synaptotagmins/metabolism

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Skocz do pozycji: 19.

Tytuł:: Cannabidiol Treatment Improves Glucose Metabolism and Memory in Streptozotocin-Induced Alzheimer's Disease Rat Model: A Proof-of-Concept Study.
Autorzy:: de Paula Faria D; Laboratory of Nuclear Medicine (LIM 43), Department of Radiology, Faculdade de Medicina, University of Sao Paulo, Sao Paulo 05403-911, SP, Brazil.
Estessi de Souza L; Laboratory of Nuclear Medicine (LIM 43), Department of Radiology, Faculdade de Medicina, University of Sao Paulo, Sao Paulo 05403-911, SP, Brazil.
Duran FLS; Laboratory of Psychiatric Neuroimaging (LIM 21), Department of Psychiatry, Faculdade de Medicina, University of Sao Paulo, Sao Paulo 05403-911, SP, Brazil.
Buchpiguel CA; Laboratory of Nuclear Medicine (LIM 43), Department of Radiology, Faculdade de Medicina, University of Sao Paulo, Sao Paulo 05403-911, SP, Brazil.
Britto LR; Institute of Biomedical Science, University of Sao Paulo, Sao Paulo 05508-000, SP, Brazil.
Crippa JAS; Department of Neuroscience and Behavioral Sciences, Ribeirão Preto Medical School, University of Sao Paulo, Ribeirão Preto 14051-160, SP, Brazil.
Filho GB; Laboratory of Psychiatric Neuroimaging (LIM 21), Department of Psychiatry, Faculdade de Medicina, University of Sao Paulo, Sao Paulo 05403-911, SP, Brazil.
Real CC; Laboratory of Nuclear Medicine (LIM 43), Department of Radiology, Faculdade de Medicina, University of Sao Paulo, Sao Paulo 05403-911, SP, Brazil.; Laboratory of Psychiatric Neuroimaging (LIM 21), Department of Psychiatry, Faculdade de Medicina, University of Sao Paulo, Sao Paulo 05403-911, SP, Brazil.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2022 Jan 19; Vol. 23 (3). Date of Electronic Publication: 2022 Jan 19.
Typ publikacji:: Journal Article
MeSH Terms:: Alzheimer Disease/*drug therapy
Alzheimer Disease/*psychology
Cannabidiol/*administration & dosage
Glucose/*metabolism
Streptozocin/*adverse effects
Alzheimer Disease/chemically induced ; Alzheimer Disease/diagnostic imaging ; Animals ; Brain/diagnostic imaging ; Brain/metabolism ; Cannabidiol/pharmacology ; Disease Models, Animal ; Fluorodeoxyglucose F18/administration & dosage ; Injections, Intraperitoneal ; Male ; Memory, Long-Term/drug effects ; Memory, Short-Term/drug effects ; Positron-Emission Tomography ; Proof of Concept Study ; Rats ; Rats, Wistar

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Skocz do pozycji: 20.

Tytuł:: Chemotherapeutics Combined with Luminal Irritants: Effects on Small-Intestinal Mannitol Permeability and Villus Length in Rats.
Autorzy:: Cano-Cebrián MJ; Department of Pharmacy, Pharmaceutical Technology and Parasitology, University of Valencia, 46100 Burjasot, Spain.; Department of Pharmaceutical Biosciences, Translational Drug Discovery and Development, Uppsala University, 752 36 Uppsala, Sweden.
Dahlgren D; Department of Pharmaceutical Biosciences, Translational Drug Discovery and Development, Uppsala University, 752 36 Uppsala, Sweden.
Kullenberg F; Department of Pharmaceutical Biosciences, Translational Drug Discovery and Development, Uppsala University, 752 36 Uppsala, Sweden.
Peters K; Department of Pharmaceutical Biosciences, Translational Drug Discovery and Development, Uppsala University, 752 36 Uppsala, Sweden.
Olander T; Department of Pharmaceutical Biosciences, Translational Drug Discovery and Development, Uppsala University, 752 36 Uppsala, Sweden.
Sjöblom M; Department of Medical Cell Biology, Division of Physiology, Uppsala University, 751 23 Uppsala, Sweden.
Lennernäs H; Department of Pharmaceutical Biosciences, Translational Drug Discovery and Development, Uppsala University, 752 36 Uppsala, Sweden.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2022 Jan 18; Vol. 23 (3). Date of Electronic Publication: 2022 Jan 18.
Typ publikacji:: Comparative Study; Journal Article
MeSH Terms:: Doxycycline/*adverse effects
Fluorouracil/*adverse effects
Intestinal Mucosa/*drug effects
Irinotecan/*adverse effects
Irritants/*adverse effects
Mannitol/*metabolism
Mucositis/*pathology
Animals ; Ethanol/adverse effects ; Injections, Intraperitoneal ; Intestinal Mucosa/metabolism ; Intestinal Mucosa/pathology ; Male ; Mucositis/chemically induced ; Mucositis/metabolism ; Organ Size/drug effects ; Permeability ; Rats ; Sodium Dodecyl Sulfate/adverse effects

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