Temat: "Injections, Intraperitoneal" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Adult mice are unresponsive to AAV8-Gremlin1 gene therapy targeting the liver.
Autorzy:: Khatib Shahidi R; The Lundberg Laboratory for Diabetes Research, Department of Molecular and Clinical Medicine, the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
M Hoffmann J; The Lundberg Laboratory for Diabetes Research, Department of Molecular and Clinical Medicine, the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Hedjazifar S; The Lundberg Laboratory for Diabetes Research, Department of Molecular and Clinical Medicine, the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Bonnet L; The Lundberg Laboratory for Diabetes Research, Department of Molecular and Clinical Medicine, the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Wallenberg Center for Molecular and Translational Medicine, University of Gothenburg, Gothenburg, Sweden.
K Baboota R; The Lundberg Laboratory for Diabetes Research, Department of Molecular and Clinical Medicine, the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Heasman S; Bioscience Metabolism, Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Cambridge, United Kingdom.
Church C; Bioscience Metabolism, Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Cambridge, United Kingdom.
Elias I; Center of Animal Biotechnology and Gene Therapy and Department of Biochemistry and Molecular Biology, School of Veterinary Medicine, Universitat Autònoma de Barcelona, Bellaterra and Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM).
Bosch F; Center of Animal Biotechnology and Gene Therapy and Department of Biochemistry and Molecular Biology, School of Veterinary Medicine, Universitat Autònoma de Barcelona, Bellaterra and Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM).
Boucher J; The Lundberg Laboratory for Diabetes Research, Department of Molecular and Clinical Medicine, the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Wallenberg Center for Molecular and Translational Medicine, University of Gothenburg, Gothenburg, Sweden.; Bioscience Metabolism, Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
Hammarstedt A; The Lundberg Laboratory for Diabetes Research, Department of Molecular and Clinical Medicine, the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Smith U; The Lundberg Laboratory for Diabetes Research, Department of Molecular and Clinical Medicine, the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2021 Feb 19; Vol. 16 (2), pp. e0247300. Date of Electronic Publication: 2021 Feb 19 (Print Publication: 2021).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Dependovirus/*genetics
Diet, High-Fat/*adverse effects
Insulin Resistance/*genetics
Intercellular Signaling Peptides and Proteins/*genetics
Intercellular Signaling Peptides and Proteins/*metabolism
Liver/*metabolism
3T3-L1 Cells ; Animals ; Body Weight ; Cell Line ; Disease Models, Animal ; Genetic Therapy ; Genetic Vectors/administration & dosage ; Glucose Tolerance Test ; Humans ; Injections, Intraperitoneal ; Intercellular Signaling Peptides and Proteins/administration & dosage ; Male ; Mice ; Recombinant Proteins/administration & dosage

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Skocz do pozycji: 2.

Tytuł:: Dual Effects of Beta-Hydroxy-Beta-Methylbutyrate (HMB) on Amino Acid, Energy, and Protein Metabolism in the Liver and Muscles of Rats with Streptozotocin-Induced Type 1 Diabetes.
Autorzy:: Holeček M; Department of Physiology, Faculty of Medicine, Charles University, 500 38 Hradec Králové, Czech Republic.
Vodeničarovová M; Department of Physiology, Faculty of Medicine, Charles University, 500 38 Hradec Králové, Czech Republic.
Fingrová R; Department of Physiology, Faculty of Medicine, Charles University, 500 38 Hradec Králové, Czech Republic.; Pokaż więcej
Źródło:: Biomolecules [Biomolecules] 2020 Oct 23; Vol. 10 (11). Date of Electronic Publication: 2020 Oct 23.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Amino Acids/*pharmacology
Diabetes Mellitus, Type 1/*drug therapy
Liver/*drug effects
Muscle, Skeletal/*drug effects
Valerates/*pharmacology
Amino Acids/administration & dosage ; Animals ; Diabetes Mellitus, Type 1/chemically induced ; Diabetes Mellitus, Type 1/metabolism ; Injections, Intraperitoneal ; Injections, Subcutaneous ; Liver/metabolism ; Male ; Muscle, Skeletal/metabolism ; Rats ; Rats, Wistar ; Streptozocin/administration & dosage ; Valerates/administration & dosage

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Skocz do pozycji: 3.

Tytuł:: Comparative effects of galactose-induced aging on mitochondrial permeability transition in rat liver and testis.
Autorzy:: Oyebode OT; Laboratories for Biomembrane Research and Biotechnology, Department of Biochemistry, University of Ibadan, Ibadan, Nigeria.
Giwa OD; Laboratories for Biomembrane Research and Biotechnology, Department of Biochemistry, University of Ibadan, Ibadan, Nigeria.
Olorunsogo OO; Laboratories for Biomembrane Research and Biotechnology, Department of Biochemistry, University of Ibadan, Ibadan, Nigeria.; Pokaż więcej
Źródło:: Toxicology mechanisms and methods [Toxicol Mech Methods] 2020 Jun; Vol. 30 (5), pp. 388-396. Date of Electronic Publication: 2020 Apr 28.
Typ publikacji:: Journal Article
MeSH Terms:: Aging/*metabolism
Galactose/*toxicity
Liver/*metabolism
Mitochondria/*metabolism
Mitochondrial Permeability Transition Pore/*metabolism
Testis/*metabolism
Adenosine Triphosphatases/metabolism ; Aging/blood ; Aging/drug effects ; Animals ; Antioxidants/metabolism ; Cytokines/blood ; Dose-Response Relationship, Drug ; Injections, Intraperitoneal ; Liver/drug effects ; Male ; Mitochondria/drug effects ; Oxidative Stress/drug effects ; Oxidative Stress/immunology ; Rats ; Rats, Wistar ; Testis/drug effects

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Skocz do pozycji: 4.

Tytuł:: Sexual Dimorphism in Doxorubicin-induced Systemic Inflammation: Implications for Hepatic Cytochrome P450 Regulation.
Autorzy:: Grant MKO; Department of Experimental and Clinical Pharmacology, University of Minnesota College of Pharmacy, Minneapolis, MN 55455, USA.
Abdelgawad IY; Department of Experimental and Clinical Pharmacology, University of Minnesota College of Pharmacy, Minneapolis, MN 55455, USA.
Lewis CA; Department of Experimental and Clinical Pharmacology, University of Minnesota College of Pharmacy, Minneapolis, MN 55455, USA.
Zordoky BN; Department of Experimental and Clinical Pharmacology, University of Minnesota College of Pharmacy, Minneapolis, MN 55455, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2020 Feb 14; Vol. 21 (4). Date of Electronic Publication: 2020 Feb 14.
Typ publikacji:: Journal Article
MeSH Terms:: Antibiotics, Antineoplastic/*pharmacology
Cytochrome P-450 Enzyme System/*metabolism
Doxorubicin/*pharmacology
Gene Expression Regulation/*drug effects
Liver/*enzymology
Animals ; Cytochrome P-450 Enzyme System/chemistry ; Cytochrome P-450 Enzyme System/genetics ; Female ; Inflammation/chemically induced ; Inflammation/metabolism ; Inflammation/pathology ; Injections, Intraperitoneal ; Interleukin-6/blood ; Isoenzymes/antagonists & inhibitors ; Isoenzymes/genetics ; Isoenzymes/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Sex Characteristics ; Tumor Necrosis Factor-alpha/blood

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Skocz do pozycji: 5.

Tytuł:: Toxic effects of VCD on kidneys and liver tissues: a histopathological and biochemical study.
Autorzy:: Ahmadian S; Women's Reproductive Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.; Department of Biology, Faculty of Science, Azarbaijan Shahid Madani University, Tabriz, Iran.
Sheshpari S; Department of Midwifery, Faculty of Nursing and Midwifery, Tabriz University of Medical Sciences, Shariati St., Tabriz, Iran.
Mahdipour M; Stem Cell Research Center, Tabriz University of Medical Sciences, Daneshgah St., Tabriz, Iran. .; Department of Reproductive Biology, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Daneshgah St., Tabriz, Iran. .
Pazhang M; Department of Biology, Faculty of Science, Azarbaijan Shahid Madani University, Tabriz, Iran.
Tsai PJ; Center for Developmental Biology and Regenerative Medicine Research, National Taiwan University/NTU, Taipei, Taiwan.; Department of Veterinary Medicine, School of Veterinary Medicine, National Taiwan University/NTU, Taipei, Taiwan.
Nouri M; Stem Cell Research Center, Tabriz University of Medical Sciences, Daneshgah St., Tabriz, Iran.; Department of Reproductive Biology, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Daneshgah St., Tabriz, Iran.
Rahbarghazi R; Stem Cell Research Center, Tabriz University of Medical Sciences, Daneshgah St., Tabriz, Iran.; Department of Applied Cell Sciences, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.
Shahnazi M; Department of Midwifery, Faculty of Nursing and Midwifery, Tabriz University of Medical Sciences, Shariati St., Tabriz, Iran. .; Pokaż więcej
Źródło:: BMC research notes [BMC Res Notes] 2019 Jul 22; Vol. 12 (1), pp. 446. Date of Electronic Publication: 2019 Jul 22.
Typ publikacji:: Journal Article
MeSH Terms:: Antineoplastic Combined Chemotherapy Protocols/*pharmacology
Kidney/*drug effects
Liver/*drug effects
Ovary/*drug effects
Alanine Transaminase/blood ; Animals ; Antineoplastic Combined Chemotherapy Protocols/toxicity ; Aspartate Aminotransferases/blood ; Creatinine/blood ; Cyclophosphamide/administration & dosage ; Cyclophosphamide/toxicity ; Dexamethasone/administration & dosage ; Dexamethasone/toxicity ; Female ; Injections, Intraperitoneal ; Kidney/pathology ; Liver/pathology ; Ovary/pathology ; Primary Ovarian Insufficiency/chemically induced ; Primary Ovarian Insufficiency/diagnosis ; Random Allocation ; Rats, Wistar ; Teniposide/administration & dosage ; Teniposide/toxicity

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Skocz do pozycji: 6.

Tytuł:: N-Acetylcysteine reverses silver nanoparticle intoxication in rats.
Autorzy:: Mendonça MCP; a Department of Biochemistry and Tissue Biology, Institute of Biology , University of Campinas , São Paulo , Brazil.
Ferreira LB; a Department of Biochemistry and Tissue Biology, Institute of Biology , University of Campinas , São Paulo , Brazil.
Rizoli C; a Department of Biochemistry and Tissue Biology, Institute of Biology , University of Campinas , São Paulo , Brazil.
Batista ÂG; b Department of Food and Nutrition , University of Campinas , São Paulo , Brazil.
Maróstica Júnior MR; b Department of Food and Nutrition , University of Campinas , São Paulo , Brazil.
da Silva EDN; c Institute of Chemistry , University of Campinas , São Paulo , Brazil.
Cadore S; c Institute of Chemistry , University of Campinas , São Paulo , Brazil.
Durán N; c Institute of Chemistry , University of Campinas , São Paulo , Brazil.; d Nanomedine Units , Federal University of ABC (UFABC) , São Paulo , Brazil.
Cruz-Höfling MAD; a Department of Biochemistry and Tissue Biology, Institute of Biology , University of Campinas , São Paulo , Brazil.
de Jesus MB; a Department of Biochemistry and Tissue Biology, Institute of Biology , University of Campinas , São Paulo , Brazil.; Pokaż więcej
Źródło:: Nanotoxicology [Nanotoxicology] 2019 Apr; Vol. 13 (3), pp. 326-338. Date of Electronic Publication: 2018 Nov 26.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Acetylcysteine/*pharmacology
Antioxidants/*pharmacology
Chemical and Drug Induced Liver Injury/*prevention & control
Liver/*drug effects
Metal Nanoparticles/*toxicity
Silver/*toxicity
Animals ; Humans ; Injections, Intraperitoneal ; Injections, Intravenous ; Male ; Metal Nanoparticles/chemistry ; Rats ; Silver/chemistry

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Skocz do pozycji: 7.

Tytuł:: In Vivo Toxicity of Solasonine and Its Effects on cyp450 Family Gene Expression in the Livers of Male Mice from Four Strains.
Autorzy:: Zhong Y; Laboratory Animal Research Center for Science and Technology, Jiangxi University of Traditional Chinese Medicine, 1688 Meiling Road, Nanchang 330004, China. .; Key Laboratory of Pharmacology of Traditional Chinese Medicine in Jiangxi, Nanchang 330004, China. .
Li S; Laboratory Animal Research Center for Science and Technology, Jiangxi University of Traditional Chinese Medicine, 1688 Meiling Road, Nanchang 330004, China. .; Key Laboratory of Pharmacology of Traditional Chinese Medicine in Jiangxi, Nanchang 330004, China. .
Chen L; Laboratory Animal Research Center for Science and Technology, Jiangxi University of Traditional Chinese Medicine, 1688 Meiling Road, Nanchang 330004, China. .; Key Laboratory of Pharmacology of Traditional Chinese Medicine in Jiangxi, Nanchang 330004, China. .
Liu Z; Laboratory Animal Research Center for Science and Technology, Jiangxi University of Traditional Chinese Medicine, 1688 Meiling Road, Nanchang 330004, China. .; Key Laboratory of Pharmacology of Traditional Chinese Medicine in Jiangxi, Nanchang 330004, China. .
Luo X; Laboratory Animal Research Center for Science and Technology, Jiangxi University of Traditional Chinese Medicine, 1688 Meiling Road, Nanchang 330004, China. .; Key Laboratory of Pharmacology of Traditional Chinese Medicine in Jiangxi, Nanchang 330004, China. .
Xu P; Laboratory Animal Research Center for Science and Technology, Jiangxi University of Traditional Chinese Medicine, 1688 Meiling Road, Nanchang 330004, China. .; Key Laboratory of Pharmacology of Traditional Chinese Medicine in Jiangxi, Nanchang 330004, China. .
Chen L; Laboratory Animal Research Center for Science and Technology, Jiangxi University of Traditional Chinese Medicine, 1688 Meiling Road, Nanchang 330004, China. .; Key Laboratory of Pharmacology of Traditional Chinese Medicine in Jiangxi, Nanchang 330004, China. .; Pokaż więcej
Źródło:: Toxins [Toxins (Basel)] 2018 Nov 23; Vol. 10 (12). Date of Electronic Publication: 2018 Nov 23.
Typ publikacji:: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cytochrome P-450 Enzyme System/*genetics
Gene Expression Regulation, Enzymologic/*drug effects
Liver/*drug effects
Solanaceous Alkaloids/*toxicity
Animals ; Body Weight/drug effects ; Injections, Intraperitoneal ; Lethal Dose 50 ; Liver/enzymology ; Liver/pathology ; Male ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Mice, Inbred ICR ; Species Specificity ; Spleen/drug effects ; Spleen/pathology

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Skocz do pozycji: 8.

Tytuł:: Dose and Exposure Time-Dependent Renal and Hepatic Effects of Intraperitoneally Administered Fumonisin B₁ in Rats.
Autorzy:: Szabó A; MTA-KE-SZIE Mycotoxins in the Food Chain Research Group, Kaposvár University, Guba S. u. 40., 7400 Kaposvár, Hungary. .; Faculty of Agricultural and Environmental Sciences, Kaposvár University, Guba S. 40., 7400 Kaposvár, Hungary. .; Somogy County Kaposi Mór Teaching Hospital, Dr. József Baka Diagnostical, Oncoradiological, Research and Educational Center, Guba S. u. 40., 7400 Kaposvár, Hungary. .
Szabó-Fodor J; MTA-KE-SZIE Mycotoxins in the Food Chain Research Group, Kaposvár University, Guba S. u. 40., 7400 Kaposvár, Hungary. .
Kachlek M; Faculty of Agricultural and Environmental Sciences, Kaposvár University, Guba S. 40., 7400 Kaposvár, Hungary. .
Mézes M; MTA-KE-SZIE Mycotoxins in the Food Chain Research Group, Kaposvár University, Guba S. u. 40., 7400 Kaposvár, Hungary. .; Faculty of Agricultural and Environmental Sciences, Department of Nutrition, Szent István University, Páter K. u. 1., 2013 Gödöllő, Hungary. .
Balogh K; MTA-KE-SZIE Mycotoxins in the Food Chain Research Group, Kaposvár University, Guba S. u. 40., 7400 Kaposvár, Hungary. .; Faculty of Agricultural and Environmental Sciences, Department of Nutrition, Szent István University, Páter K. u. 1., 2013 Gödöllő, Hungary. .
Glávits R; Autopsy Ltd., Telepes u. 42., 1147 Budapest, Hungary. .
Ali O; Faculty of Agricultural and Environmental Sciences, Kaposvár University, Guba S. 40., 7400 Kaposvár, Hungary. .
Zeebone YY; Faculty of Agricultural and Environmental Sciences, Kaposvár University, Guba S. 40., 7400 Kaposvár, Hungary. .
Kovács M; MTA-KE-SZIE Mycotoxins in the Food Chain Research Group, Kaposvár University, Guba S. u. 40., 7400 Kaposvár, Hungary. .; Faculty of Agricultural and Environmental Sciences, Kaposvár University, Guba S. 40., 7400 Kaposvár, Hungary. .; Pokaż więcej
Źródło:: Toxins [Toxins (Basel)] 2018 Nov 09; Vol. 10 (11). Date of Electronic Publication: 2018 Nov 09.
Typ publikacji:: Journal Article
MeSH Terms:: Fumonisins/*toxicity
Kidney/*drug effects
Liver/*drug effects
Animals ; Dose-Response Relationship, Drug ; Fumonisins/administration & dosage ; Glutathione/metabolism ; Glutathione Peroxidase/metabolism ; Injections, Intraperitoneal ; Kidney/metabolism ; Kidney/pathology ; Liver/metabolism ; Liver/pathology ; Lung/anatomy & histology ; Lung/drug effects ; Lung/metabolism ; Male ; Oxidative Stress/drug effects ; Rats, Wistar ; Time Factors

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Skocz do pozycji: 9.

Tytuł:: Synthesis, characterization and in vivo evaluation of cadmium telluride quantum dots toxicity in mice by toxicometabolomics approach.
Autorzy:: Khoshkam M; a Chemistry Group, Faculty of Basic Sciences , University of Mohaghegh Ardabili , Ardabil , Iran.
Baghdadchi Y; b Cancer Gene Therapy Research Center, Zanjan University of Medical Sciences , Zanjan , Iran.
Arezumand R; c Department of Medical Biotechnology and Molecular Science, School of Medicine , North Khorasan University of Medical Sciences , Bojnurd , Iran.
Ramazani A; b Cancer Gene Therapy Research Center, Zanjan University of Medical Sciences , Zanjan , Iran.; Pokaż więcej
Źródło:: Toxicology mechanisms and methods [Toxicol Mech Methods] 2018 Sep; Vol. 28 (7), pp. 539-546. Date of Electronic Publication: 2018 May 21.
Typ publikacji:: Comparative Study; Journal Article
MeSH Terms:: Cadmium Compounds/*toxicity
Endoplasmic Reticulum/*drug effects
Liver/*drug effects
Oxidative Stress/*drug effects
Quantum Dots/*toxicity
Tellurium/*toxicity
Testis/*drug effects
Animals ; Cadmium/chemistry ; Cadmium/toxicity ; Cadmium Compounds/administration & dosage ; Cadmium Compounds/chemistry ; Cadmium Poisoning/enzymology ; Cadmium Poisoning/metabolism ; Cadmium Poisoning/pathology ; Dose-Response Relationship, Drug ; Endoplasmic Reticulum/enzymology ; Endoplasmic Reticulum/metabolism ; Injections, Intraperitoneal ; Kidney/drug effects ; Kidney/metabolism ; Kidney/pathology ; Liver/metabolism ; Liver/pathology ; Male ; Metabolomics/methods ; Mice ; Organ Specificity ; Particle Size ; Principal Component Analysis ; Quantum Dots/administration & dosage ; Random Allocation ; Spleen/drug effects ; Spleen/metabolism ; Spleen/pathology ; Surface Properties ; Tellurium/administration & dosage ; Tellurium/chemistry ; Testis/metabolism ; Testis/pathology ; Toxicity Tests, Chronic

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Skocz do pozycji: 10.

Tytuł:: Effect of Endoplasmic Reticular Stress on Free Hemoglobin Metabolism and Liver Injury.
Autorzy:: Tseng SH; Department of Physical Medicine and Rehabilitation, Taipei Medical University Hospital, Taipei 110, Taiwan. .; Department of Physical Medicine and Rehabilitation, School of Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan. .
Chang TY; School of Nutrition and Health Sciences, College of Nutrition, Taipei Medical University, Taipei 110, Taiwan. .
Shih CK; School of Nutrition and Health Sciences, College of Nutrition, Taipei Medical University, Taipei 110, Taiwan. .; School of Food Safety, College of Nutrition, Taipei Medical University, Taipei 110, Taiwan. .
Hsieh RH; School of Nutrition and Health Sciences, College of Nutrition, Taipei Medical University, Taipei 110, Taiwan. .
Chen CW; School of Nutrition and Health Sciences, College of Nutrition, Taipei Medical University, Taipei 110, Taiwan. .
Chen YC; School of Nutrition and Health Sciences, College of Nutrition, Taipei Medical University, Taipei 110, Taiwan. .
Lin MH; Department of Pharmaceutical Science, School of Pharmacy, Taipei Medical University, Taipei 110, Taiwan. .
Chang JS; School of Nutrition and Health Sciences, College of Nutrition, Taipei Medical University, Taipei 110, Taiwan. .; Graduate Institute of Metabolism and Obesity Sciences, College of Nutrition, Taipei Medical University, Taipei 110, Taiwan. .; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2018 Jul 06; Vol. 19 (7). Date of Electronic Publication: 2018 Jul 06.
Typ publikacji:: Journal Article
MeSH Terms:: Endoplasmic Reticulum Stress/*physiology
Hemoglobins/*metabolism
Liver/*pathology
Tunicamycin/*adverse effects
Animals ; Antigens, CD/metabolism ; Antigens, Differentiation, Myelomonocytic/metabolism ; Bilirubin/blood ; Cathepsin D/metabolism ; Endoplasmic Reticulum Stress/drug effects ; Erythrocytes/metabolism ; Heme/metabolism ; Hemoglobins/administration & dosage ; Injections, Intraperitoneal ; Injections, Intravenous ; Iron/blood ; Lactoylglutathione Lyase/metabolism ; Liver/drug effects ; Male ; Peptide Fragments/blood ; Rats ; Rats, Sprague-Dawley ; Receptors, Cell Surface/metabolism ; Tunicamycin/administration & dosage

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Skocz do pozycji: 11.

Tytuł:: Immune neutralization of the receptor for advanced glycation end products reduce liver oxidative damage induced by an acute systemic injection of lipopolysaccharide.
Autorzy:: Tiefensee Ribeiro C; Centro de Estudos em Estresse Oxidativo.
Gasparotto J; Centro de Estudos em Estresse Oxidativo.
Teixeira AA; Centro de Estudos em Estresse Oxidativo.
Portela LVC; Laboratório de Neurotrauma e Biomarcadores, Departamento de Bioquímica, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos, 2600-Anexo, CEP 90035-003 Porto Alegre, Rio Grande do Sul, Brazil.
Flores VNL; Centro de Estudos em Estresse Oxidativo.
Moreira JCF; Centro de Estudos em Estresse Oxidativo.
Gelain DP; Centro de Estudos em Estresse Oxidativo.; Pokaż więcej
Źródło:: Journal of biochemistry [J Biochem] 2018 Jun 01; Vol. 163 (6), pp. 515-523.
Typ publikacji:: Journal Article
MeSH Terms:: Oxidative Stress*/drug effects
Antibodies/*immunology
Lipopolysaccharides/*administration & dosage
Lipopolysaccharides/*immunology
Liver/*metabolism
Receptor for Advanced Glycation End Products/*antagonists & inhibitors
Receptor for Advanced Glycation End Products/*immunology
Animals ; Antibodies/administration & dosage ; Antibodies/pharmacology ; Inflammation/immunology ; Inflammation/metabolism ; Injections, Intraperitoneal ; Liver/drug effects ; Male ; Rats ; Rats, Wistar ; Reactive Oxygen Species/metabolism ; Receptor for Advanced Glycation End Products/metabolism

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Skocz do pozycji: 12.

Tytuł:: Liquid chromatography mass spectrometry-based profiling of phosphatidylcholine and phosphatidylethanolamine in the plasma and liver of acetaminophen-induced liver injured mice.
Autorzy:: Ming YN; Division of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai Institute of Digestive Disease, Shanghai, China.
Zhang JY; Division of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai Institute of Digestive Disease, Shanghai, China.
Wang XL; Department of Pharmacology, School of Medicine, Shanghai Jiao Tong University, Institute of Medical Sciences, Shanghai, China.
Li CM; Division of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai Institute of Digestive Disease, Shanghai, China.
Ma SC; Department of Interventional Oncology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Wang ZY; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fudan University, Shanghai, 200032, China.
Liu XL; Division of Gastroenterology and Hepatology, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Li XB; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fudan University, Shanghai, 200032, China. .
Mao YM; Division of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai Institute of Digestive Disease, Shanghai, China. .; Pokaż więcej
Źródło:: Lipids in health and disease [Lipids Health Dis] 2017 Aug 14; Vol. 16 (1), pp. 153. Date of Electronic Publication: 2017 Aug 14.
Typ publikacji:: Journal Article
MeSH Terms:: Acetaminophen/*adverse effects
Chemical and Drug Induced Liver Injury/*metabolism
Liver/*drug effects
Phosphatidylcholines/*metabolism
Phosphatidylethanolamines/*metabolism
Animals ; Chemical and Drug Induced Liver Injury/etiology ; Chemical and Drug Induced Liver Injury/pathology ; Choline Kinase/genetics ; Choline Kinase/metabolism ; Chromatography, Liquid ; Gene Expression Regulation ; Hepatocytes/drug effects ; Hepatocytes/metabolism ; Hepatocytes/pathology ; Injections, Intraperitoneal ; Liver/metabolism ; Liver/pathology ; Male ; Mass Spectrometry ; Mice ; Mice, Inbred C57BL ; Phosphatidylethanolamine N-Methyltransferase/genetics ; Phosphatidylethanolamine N-Methyltransferase/metabolism ; Phospholipases/genetics ; Phospholipases/metabolism

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Skocz do pozycji: 13.

Tytuł:: The effect of NaCl on the level of reduced sulfur compounds in rat liver. Implications for blood pressure increase.
Autorzy:: Iciek M; Chair of Medical Biochemistry, Jagiellonian University Medical College, Kraków, Poland.
Kotańska M; Department of Pharmacodynamics Jagiellonian University Medical College, Kraków, Poland.
Knutelska J; Laboratory of Pharmacological Screening, Department of Pharmacodynamics Jagiellonian University Medical College, Kraków, Poland.
Bednarski M; Laboratory of Pharmacological Screening, Department of Pharmacodynamics Jagiellonian University Medical College, Kraków, Poland.
Zygmunt M; Laboratory of Pharmacological Screening, Department of Pharmacodynamics Jagiellonian University Medical College, Kraków, Poland.
Kowalczyk-Pachel D; Chair of Medical Biochemistry, Jagiellonian University Medical College, Kraków, Poland.
Bilska-Wilkosz A; Chair of Medical Biochemistry, Jagiellonian University Medical College, Kraków, Poland.
Górny M; Chair of Medical Biochemistry, Jagiellonian University Medical College, Kraków, Poland.
Sokołowska-Jeżewicz M; Chair of Medical Biochemistry, Jagiellonian University Medical College, Kraków, Poland.; Pokaż więcej
Źródło:: Postepy higieny i medycyny doswiadczalnej (Online) [Postepy Hig Med Dosw (Online)] 2017 Jul 07; Vol. 71 (0), pp. 564-576. Date of Electronic Publication: 2017 Jul 07.
Typ publikacji:: Journal Article
MeSH Terms:: Free Radicals/*analysis
Hypertension/*drug therapy
Liver/*drug effects
Sodium Chloride/*pharmacology
Sulfur Compounds/*chemistry
Animals ; Cysteine/metabolism ; Hydrogen Sulfide/analysis ; Hydrogen Sulfide/chemistry ; Hydrogen Sulfide/metabolism ; Hypertension/metabolism ; Injections, Intraperitoneal ; Injections, Intravenous ; Liver/metabolism ; Male ; Rats ; Rats, Wistar ; Sodium Chloride/toxicity ; Sulfur Compounds/analysis ; Sulfur Compounds/metabolism ; Sulfurtransferases/metabolism

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Skocz do pozycji: 14.

Tytuł:: The effect of carnosine on methylglyoxal-induced oxidative stress in rats.
Autorzy:: Yılmaz Z; a Department of Biochemistry , Istanbul Medical Faculty, Istanbul University , Istanbul , Turkey , and.
Kalaz EB; a Department of Biochemistry , Istanbul Medical Faculty, Istanbul University , Istanbul , Turkey , and.
Aydın AF; a Department of Biochemistry , Istanbul Medical Faculty, Istanbul University , Istanbul , Turkey , and.
Soluk-Tekkeşin M; b Department of Pathology, Oncology Institute , Istanbul University , Istanbul , Turkey.
Doğru-Abbasoğlu S; a Department of Biochemistry , Istanbul Medical Faculty, Istanbul University , Istanbul , Turkey , and.
Uysal M; a Department of Biochemistry , Istanbul Medical Faculty, Istanbul University , Istanbul , Turkey , and.
Koçak-Toker N; a Department of Biochemistry , Istanbul Medical Faculty, Istanbul University , Istanbul , Turkey , and.; Pokaż więcej
Źródło:: Archives of physiology and biochemistry [Arch Physiol Biochem] 2017 Jul; Vol. 123 (3), pp. 192-198. Date of Electronic Publication: 2017 Mar 06.
Typ publikacji:: Journal Article
MeSH Terms:: Advanced Oxidation Protein Products/*antagonists & inhibitors
Antioxidants/*pharmacology
Carnosine/*pharmacology
Glycation End Products, Advanced/*antagonists & inhibitors
Liver/*drug effects
Pyruvaldehyde/*antagonists & inhibitors
Advanced Oxidation Protein Products/agonists ; Advanced Oxidation Protein Products/metabolism ; Animals ; Glycation End Products, Advanced/agonists ; Glycation End Products, Advanced/metabolism ; Injections, Intraperitoneal ; Lipid Peroxidation/drug effects ; Liver/metabolism ; Male ; Oxidative Stress/drug effects ; Protein Carbonylation ; Pyruvaldehyde/toxicity ; Rats ; Rats, Sprague-Dawley ; Reactive Oxygen Species/agonists ; Reactive Oxygen Species/antagonists & inhibitors ; Reactive Oxygen Species/metabolism ; Thiobarbituric Acid Reactive Substances/metabolism

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Skocz do pozycji: 15.

Tytuł:: Protective Effect of Quercetin Against Oxidative Stress-induced Toxicity Associated With Doxorubicin and Cyclophosphamide in Rat Kidney and Liver Tissue.
Autorzy:: Kocahan S; Department of Physiology, Faculty of Medicine, Adiyaman University, Adiyaman, Turkey; International Scientific Center, Baku State University, Baku, Azerbaijan. .
Dogan Z
Erdemli E
Taskin E; Pokaż więcej
Źródło:: Iranian journal of kidney diseases [Iran J Kidney Dis] 2017 Mar; Vol. 11 (2), pp. 124-131.
Typ publikacji:: Journal Article
MeSH Terms:: Antioxidants/*administration & dosage
Cyclophosphamide/*adverse effects
Doxorubicin/*adverse effects
Kidney/*drug effects
Liver/*drug effects
Quercetin/*administration & dosage
Animals ; Antineoplastic Agents/toxicity ; Catalase/metabolism ; Female ; Glutathione/metabolism ; Glutathione Peroxidase/metabolism ; Injections, Intraperitoneal ; Kidney/metabolism ; Liver/metabolism ; Male ; Malondialdehyde/metabolism ; Oxidative Stress/drug effects ; Pregnancy ; Rats ; Rats, Wistar ; Superoxide Dismutase/metabolism

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Skocz do pozycji: 16.

Tytuł:: Characterization of pathogenesis of and immune response to Burkholderia pseudomallei K96243 using both inhalational and intraperitoneal infection models in BALB/c and C57BL/6 mice.
Autorzy:: Bearss JJ; Pathology Division, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), Fort Detrick, Frederick, MD, United States of America.
Hunter M; Bacteriology Division, USAMRIID, Fort Detrick, Frederick, MD, United States of America.
Dankmeyer JL; Bacteriology Division, USAMRIID, Fort Detrick, Frederick, MD, United States of America.
Fritts KA; Bacteriology Division, USAMRIID, Fort Detrick, Frederick, MD, United States of America.
Klimko CP; Bacteriology Division, USAMRIID, Fort Detrick, Frederick, MD, United States of America.
Weaver CH; Bacteriology Division, USAMRIID, Fort Detrick, Frederick, MD, United States of America.
Shoe JL; Bacteriology Division, USAMRIID, Fort Detrick, Frederick, MD, United States of America.
Quirk AV; Bacteriology Division, USAMRIID, Fort Detrick, Frederick, MD, United States of America.
Toothman RG; Bacteriology Division, USAMRIID, Fort Detrick, Frederick, MD, United States of America.
Webster WM; Bacteriology Division, USAMRIID, Fort Detrick, Frederick, MD, United States of America.
Fetterer DP; BioStatisitics Division, USAMRIID, Fort Detrick, Frederick, MD, United States of America.
Bozue JA; Bacteriology Division, USAMRIID, Fort Detrick, Frederick, MD, United States of America.
Worsham PL; Bacteriology Division, USAMRIID, Fort Detrick, Frederick, MD, United States of America.
Welkos SL; Bacteriology Division, USAMRIID, Fort Detrick, Frederick, MD, United States of America.
Amemiya K; Bacteriology Division, USAMRIID, Fort Detrick, Frederick, MD, United States of America.
Cote CK; Bacteriology Division, USAMRIID, Fort Detrick, Frederick, MD, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2017 Feb 24; Vol. 12 (2), pp. e0172627. Date of Electronic Publication: 2017 Feb 24 (Print Publication: 2017).
Typ publikacji:: Journal Article
MeSH Terms:: Immunity, Innate*
Burkholderia pseudomallei/*immunology
Liver/*immunology
Lung/*immunology
Melioidosis/*immunology
Spleen/*immunology
Administration, Inhalation ; Animals ; Bacterial Load ; Body Temperature ; Body Weight ; Burkholderia pseudomallei/growth & development ; Burkholderia pseudomallei/pathogenicity ; Colony Count, Microbial ; Cytokines/biosynthesis ; Cytokines/immunology ; Disease Models, Animal ; Female ; Granulocytes/immunology ; Granulocytes/microbiology ; Humans ; Injections, Intraperitoneal ; Liver/microbiology ; Lung/microbiology ; Lymphocyte Subsets/classification ; Lymphocyte Subsets/immunology ; Lymphocyte Subsets/microbiology ; Melioidosis/microbiology ; Melioidosis/pathology ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Monocytes/immunology ; Monocytes/microbiology ; Species Specificity ; Spleen/microbiology

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Skocz do pozycji: 17.

Tytuł:: In vivo Lipopolysaccharide Tolerance Recruits CD11b+ Macrophages to the Liver with Enhanced Bactericidal Activity and Low Tumor Necrosis Factor-Releasing Capability, Resulting in Drastic Resistance to Lethal Septicemia.
Autorzy:: Kinoshita M; Department of Immunology and Microbiology, National Defense Medical College, Tokorozawa, Japan.
Miyazaki H
Nakashima H
Nakashima M
Nishikawa M
Ishikiriyama T
Kato S
Iwaya K
Hiroi S
Shinomiya N
Seki S; Pokaż więcej
Źródło:: Journal of innate immunity [J Innate Immun] 2017; Vol. 9 (5), pp. 493-510. Date of Electronic Publication: 2017 Jul 05.
Typ publikacji:: Journal Article
MeSH Terms:: Escherichia coli/*immunology
Escherichia coli Infections/*immunology
Lipopolysaccharides/*immunology
Liver/*pathology
Macrophages/*immunology
Sepsis/*immunology
Animals ; Bacteriolysis ; CD11b Antigen/metabolism ; Cell Movement ; Cells, Cultured ; Immune Tolerance ; Immunity ; Injections, Intraperitoneal ; Male ; Mice ; Mice, Inbred C57BL ; Phagocytosis ; Receptors, IgG/metabolism ; Tumor Necrosis Factor-alpha/metabolism

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Skocz do pozycji: 18.

Tytuł:: Treatment with didemnin B, an elongation factor 1A inhibitor, improves hepatic lipotoxicity in obese mice.
Autorzy:: Hetherington AM; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry Western University, London, Ontario, Canada.
Sawyez CG; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry Western University, London, Ontario, Canada Robarts Research Institute, Schulich School of Medicine and Dentistry Western University, London, Ontario, Canada Department of Medicine, Schulich School of Medicine and Dentistry Western University, London, Ontario, Canada.
Sutherland BG; Robarts Research Institute, Schulich School of Medicine and Dentistry Western University, London, Ontario, Canada.
Robson DL; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry Western University, London, Ontario, Canada.
Arya R; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry Western University, London, Ontario, Canada.
Kelly K; Metabolic and Cardiovascular Diseases Laboratory, Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Alberta, Canada.
Jacobs RL; Metabolic and Cardiovascular Diseases Laboratory, Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Alberta, Canada.
Borradaile NM; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry Western University, London, Ontario, Canada .; Pokaż więcej
Źródło:: Physiological reports [Physiol Rep] 2016 Sep; Vol. 4 (17).
Typ publikacji:: Journal Article
MeSH Terms:: Depsipeptides/*pharmacology
Hep G2 Cells/*pathology
Hepatocytes/*drug effects
Hepatocytes/*pathology
Immunosuppressive Agents/*pharmacology
Liver/*pathology
Non-alcoholic Fatty Liver Disease/*metabolism
Peptide Elongation Factor 1/*antagonists & inhibitors
Peptide Elongation Factor 1/*metabolism
Animals ; Cell Death ; Depsipeptides/administration & dosage ; Depsipeptides/metabolism ; Eating/drug effects ; Endoplasmic Reticulum/metabolism ; Endoplasmic Reticulum Chaperone BiP ; Endoplasmic Reticulum Stress/drug effects ; Fatty Acids/metabolism ; Gene Expression ; Heat-Shock Proteins/metabolism ; Hep G2 Cells/metabolism ; Hep G2 Cells/ultrastructure ; Hepatocytes/metabolism ; Hepatocytes/ultrastructure ; Humans ; Immunosuppressive Agents/administration & dosage ; Immunosuppressive Agents/metabolism ; Injections, Intraperitoneal ; Lipid Metabolism/drug effects ; Liver/enzymology ; Liver/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Obese ; Non-alcoholic Fatty Liver Disease/drug therapy ; Non-alcoholic Fatty Liver Disease/pathology

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Skocz do pozycji: 19.

Tytuł:: Impact of e-cigarette refill liquid with or without nicotine on liver function in adult rats.
Autorzy:: El Golli N; a LMBA, Department of Biology Faculty of Sciences , Tunis , Tunisia .
Jrad-Lamine A; a LMBA, Department of Biology Faculty of Sciences , Tunis , Tunisia .
Neffati H; a LMBA, Department of Biology Faculty of Sciences , Tunis , Tunisia .
Rahali D; a LMBA, Department of Biology Faculty of Sciences , Tunis , Tunisia .
Dallagi Y; a LMBA, Department of Biology Faculty of Sciences , Tunis , Tunisia .
Dkhili H; a LMBA, Department of Biology Faculty of Sciences , Tunis , Tunisia .
Ba N; b INSERM US32, Kremlin-Bicêtre Hospital , Bicêtre , France , and.
El May MV; c Laboratory of Histology Faculty of Medicine of Tunis , University of Tunis, El Manar , Tunis , Tunisia.
El Fazaa S; a LMBA, Department of Biology Faculty of Sciences , Tunis , Tunisia .; Pokaż więcej
Źródło:: Toxicology mechanisms and methods [Toxicol Mech Methods] 2016 Jul; Vol. 26 (6), pp. 419-26. Date of Electronic Publication: 2016 Mar 22.
Typ publikacji:: Journal Article
MeSH Terms:: Electronic Nicotine Delivery Systems/*adverse effects
Lipid Peroxidation/*drug effects
Liver/*drug effects
Nicotine/*toxicity
Oxidative Stress/*drug effects
Animals ; Biomarkers/blood ; Injections, Intraperitoneal ; Liver/enzymology ; Liver/pathology ; Liver Function Tests ; Male ; Nicotine/administration & dosage ; Organ Size/drug effects ; Rats, Wistar

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Skocz do pozycji: 20.

Tytuł:: The effect of ageing on isoniazid pharmacokinetics and hepatotoxicity in Fischer 344 rats.
Autorzy:: Mach J; Laboratory of Ageing and Pharmacology, Kolling Institute of Medical Research, Sydney, NSW, Australia.; Department of Clin Pharmacol and Aged Care, Royal North Shore Hosp, Sydney, NSW, Australia.; Sydney Medical School, Univ of Sydney, Sydney, NSW, Australia.
Huizer-Pajkos A; Laboratory of Ageing and Pharmacology, Kolling Institute of Medical Research, Sydney, NSW, Australia.; Department of Clin Pharmacol and Aged Care, Royal North Shore Hosp, Sydney, NSW, Australia.
Mitchell SJ; Translational Gerontology Branch, National Institute on Aging, National Institute of Health, Baltimore, Maryland, USA.
McKenzie C; Pathology Department, Royal Prince Alfred Hosp, Sydney, NSW, Australia.
Phillips L; Mass Spec Imaging and Proteomics Laboratory, Kolling institute of Medical Research, Sydney, NSW, Australia.
Kane A; Laboratory of Ageing and Pharmacology, Kolling Institute of Medical Research, Sydney, NSW, Australia.; Department of Clin Pharmacol and Aged Care, Royal North Shore Hosp, Sydney, NSW, Australia.; Sydney Medical School, Univ of Sydney, Sydney, NSW, Australia.
Jones B; Sydney Medical School, Univ of Sydney, Sydney, NSW, Australia.; Department of Gastroenterology, Kolling Institute of Medical Research, Sydney, NSW, Australia.
de Cabo R; Translational Gerontology Branch, National Institute on Aging, National Institute of Health, Baltimore, Maryland, USA.
Cogger V; Sydney Medical School, Univ of Sydney, Sydney, NSW, Australia.; Ageing and Alzheimers Institute, Centre for Education and Research on Ageing and Anzac Research Institute, Concord Hospital and University of Sydney, Sydney, NSW, Australia.
Le Couteur DG; Sydney Medical School, Univ of Sydney, Sydney, NSW, Australia.; Ageing and Alzheimers Institute, Centre for Education and Research on Ageing and Anzac Research Institute, Concord Hospital and University of Sydney, Sydney, NSW, Australia.
Hilmer SN; Laboratory of Ageing and Pharmacology, Kolling Institute of Medical Research, Sydney, NSW, Australia.; Department of Clin Pharmacol and Aged Care, Royal North Shore Hosp, Sydney, NSW, Australia.; Sydney Medical School, Univ of Sydney, Sydney, NSW, Australia.; Pokaż więcej
Źródło:: Fundamental & clinical pharmacology [Fundam Clin Pharmacol] 2016 Feb; Vol. 30 (1), pp. 23-34. Date of Electronic Publication: 2015 Nov 09.
Typ publikacji:: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Aging/*metabolism
Antitubercular Agents/*pharmacokinetics
Chemical and Drug Induced Liver Injury/*metabolism
Isoniazid/*pharmacokinetics
Liver/*drug effects
Aging/blood ; Animals ; Antitubercular Agents/administration & dosage ; Antitubercular Agents/toxicity ; Biomarkers/blood ; Chemical and Drug Induced Liver Injury/blood ; Chemical and Drug Induced Liver Injury/etiology ; Chemical and Drug Induced Liver Injury/pathology ; Dose-Response Relationship, Drug ; Injections, Intraperitoneal ; Isoniazid/administration & dosage ; Isoniazid/toxicity ; Liver/enzymology ; Liver/pathology ; Rats, Inbred F344

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