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Wyszukujesz frazę ""Injections, Intraventricular"" wg kryterium: Temat


Tytuł :
Use of Intraventricular Medications in Critically Ill Patients: A Systematic Review.
Autorzy :
Erdman MJ; Department of Pharmacy, UF Health Jacksonville, Jacksonville, Florida (Drs Erdman and Marrese); Department of Pharmacy, St Josephs Hospital and Medical Center, Phoenix, Arizona (Dr Haller); and Department of Pharmacy, University Health System, San Antonio, Texas (Drs Barthol and Small).
Marrese AR
Haller JT
Barthol CA
Small CE
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Źródło :
Critical care nursing quarterly [Crit Care Nurs Q] 2020 Apr/Jun; Vol. 43 (2), pp. 157-171.
Typ publikacji :
Journal Article; Systematic Review
MeSH Terms :
Critical Illness*
Injections, Intraventricular*
Fibrinolytic Agents/*therapeutic use
Nicardipine/*therapeutic use
Tissue Plasminogen Activator/*therapeutic use
Vasodilator Agents/*therapeutic use
Aminoglycosides/therapeutic use ; Anti-Bacterial Agents/therapeutic use ; Humans ; Intensive Care Units
Czasopismo naukowe
Tytuł :
In Vivo Intracerebral Stereotaxic Injections for Optogenetic Stimulation of Long-Range Inputs in Mouse Brain Slices.
Autorzy :
Richevaux L; CNRS (Integrative Neuroscience and Cognition Center, UMR 8002); Université Paris Descartes, Sorbonne Paris Cité; .
Schenberg L; CNRS (Integrative Neuroscience and Cognition Center, UMR 8002); Université Paris Descartes, Sorbonne Paris Cité.
Beraneck M; CNRS (Integrative Neuroscience and Cognition Center, UMR 8002); Université Paris Descartes, Sorbonne Paris Cité.
Fricker D; CNRS (Integrative Neuroscience and Cognition Center, UMR 8002); Université Paris Descartes, Sorbonne Paris Cité; .
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Źródło :
Journal of visualized experiments : JoVE [J Vis Exp] 2019 Sep 20 (151). Date of Electronic Publication: 2019 Sep 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Video-Audio Media
MeSH Terms :
Injections, Intraventricular*
Stereotaxic Techniques*
Brain/*drug effects
Channelrhodopsins/*administration & dosage
Genetic Vectors/*administration & dosage
Optogenetics/*methods
Animals ; Axons/metabolism ; Brain/physiology ; Channelrhodopsins/metabolism ; Dependovirus ; Mice ; Neurons/drug effects ; Neurons/physiology ; Patch-Clamp Techniques
Czasopismo naukowe
Tytuł :
Transcriptomic analysis links diverse hypothalamic cell types to fibroblast growth factor 1-induced sustained diabetes remission.
Autorzy :
Bentsen MA; UW Medicine Diabetes Institute, University of Washington, Seattle, WA, USA.; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Rausch DM; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Mirzadeh Z; Barrow Neurological Institute, Phoenix, AZ, USA.
Muta K; UW Medicine Diabetes Institute, University of Washington, Seattle, WA, USA.; Chakri Naruebodindra Medical Institute, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Scarlett JM; UW Medicine Diabetes Institute, University of Washington, Seattle, WA, USA.; Department of Pediatric Gastroenterology and Hepatology, Seattle Children's Hospital, Seattle, WA, USA.
Brown JM; UW Medicine Diabetes Institute, University of Washington, Seattle, WA, USA.
Herranz-Pérez V; Cavanilles Institute of Biodiversity and Evolutionary Biology, University of Valencia, Valencia, Spain.; Predepartamental Unit of Medicine, Jaume I University, Castelló de la Plana, Spain.
Baquero AF; Obesity Research Unit, Novo Nordisk Research Center Seattle, Inc., Seattle, WA, USA.
Thompson J; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Alonge KM; UW Medicine Diabetes Institute, University of Washington, Seattle, WA, USA.
Faber CL; UW Medicine Diabetes Institute, University of Washington, Seattle, WA, USA.
Kaiyala KJ; Department of Oral Health Sciences, School of Dentistry, University of Washington, Seattle, WA, USA.
Bennett C; Obesity Research Unit, Novo Nordisk Research Center Seattle, Inc., Seattle, WA, USA.
Pyke C; Pathology & Imaging, Global Discovery and Development Sciences, Novo Nordisk A/S, Maaloev, Denmark.
Ratner C; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Egerod KL; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Holst B; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Meek TH; Obesity Research Unit, Novo Nordisk Research Center Seattle, Inc., Seattle, WA, USA.
Kutlu B; Obesity Research Unit, Novo Nordisk Research Center Seattle, Inc., Seattle, WA, USA.
Zhang Y; Obesity Research Unit, Novo Nordisk Research Center Seattle, Inc., Seattle, WA, USA.
Sparso T; Bioinformatics and Data Mining, Global Research Technologies, Novo Nordisk A/S, Maaloev, Denmark.
Grove KL; Obesity Research Unit, Novo Nordisk Research Center Seattle, Inc., Seattle, WA, USA.
Morton GJ; UW Medicine Diabetes Institute, University of Washington, Seattle, WA, USA.
Kornum BR; Department of Neuroscience, University of Copenhagen, Copenhagen, Denmark.
García-Verdugo JM; Cavanilles Institute of Biodiversity and Evolutionary Biology, University of Valencia, Valencia, Spain.
Secher A; Diabetes Research, Global Drug Discovery, Novo Nordisk A/S, Maaloev, Denmark.
Jorgensen R; Diabetes Research, Global Drug Discovery, Novo Nordisk A/S, Maaloev, Denmark.; Cytoki Pharma, Copenhagen, Denmark.
Schwartz MW; UW Medicine Diabetes Institute, University of Washington, Seattle, WA, USA. .
Pers TH; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. .
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Źródło :
Nature communications [Nat Commun] 2020 Sep 07; Vol. 11 (1), pp. 4458. Date of Electronic Publication: 2020 Sep 07.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Diabetes Mellitus, Experimental/*diet therapy
Diabetes Mellitus, Type 2/*drug therapy
Fibroblast Growth Factor 1/*administration & dosage
Hypoglycemic Agents/*administration & dosage
Hypothalamus/*drug effects
Recombinant Proteins/*administration & dosage
Agouti-Related Protein/metabolism ; Animals ; Astrocytes/drug effects ; Astrocytes/metabolism ; Blood Glucose/analysis ; Cell Communication ; Cell Nucleus/drug effects ; Cell Nucleus/metabolism ; Diabetes Mellitus, Experimental/blood ; Diabetes Mellitus, Experimental/etiology ; Diabetes Mellitus, Experimental/pathology ; Diabetes Mellitus, Type 2/blood ; Diabetes Mellitus, Type 2/etiology ; Diabetes Mellitus, Type 2/pathology ; Diet, High-Fat/adverse effects ; Dietary Sucrose/administration & dosage ; Dietary Sucrose/adverse effects ; Humans ; Hypothalamus/cytology ; Hypothalamus/pathology ; Injections, Intraventricular ; Leptin/genetics ; Male ; Melanocortins/metabolism ; Melanocyte-Stimulating Hormones/administration & dosage ; Mice ; Mice, Knockout ; Neurons/drug effects ; Neurons/metabolism ; Oligodendroglia/drug effects ; Oligodendroglia/metabolism ; RNA-Seq ; Receptor, Melanocortin, Type 4/genetics ; Receptors, Melanocortin/antagonists & inhibitors ; Receptors, Melanocortin/metabolism ; Remission Induction/methods ; Signal Transduction/drug effects ; Single-Cell Analysis ; Stereotaxic Techniques ; Transcriptome/drug effects
Czasopismo naukowe
Tytuł :
Vascular Endothelial Growth Factor 165-Binding Heparan Sulfate Promotes Functional Recovery From Cerebral Ischemia.
Autorzy :
Chan SJ; Department of Radiology (S.J.C., E.E., K.H., E.M., S.G., E.H.L.), Massachusetts General Hospital, Harvard Medical School, Charlestown.; Institute of Medical Biology, Glycotherapeutics Group, A*STAR (S.J.C., R.A.A.S., S.M.C., V.N.).
Esposito E; Department of Radiology (S.J.C., E.E., K.H., E.M., S.G., E.H.L.), Massachusetts General Hospital, Harvard Medical School, Charlestown.
Hayakawa K; Department of Radiology (S.J.C., E.E., K.H., E.M., S.G., E.H.L.), Massachusetts General Hospital, Harvard Medical School, Charlestown.; Department of Neurology (K.H., E.H.L.), Massachusetts General Hospital, Harvard Medical School, Charlestown.
Mandaville E; Department of Radiology (S.J.C., E.E., K.H., E.M., S.G., E.H.L.), Massachusetts General Hospital, Harvard Medical School, Charlestown.
Smith RAA; Institute of Medical Biology, Glycotherapeutics Group, A*STAR (S.J.C., R.A.A.S., S.M.C., V.N.).
Guo S; Department of Radiology (S.J.C., E.E., K.H., E.M., S.G., E.H.L.), Massachusetts General Hospital, Harvard Medical School, Charlestown.
Niu W; Tissue Engineering Laboratories, VA Boston Healthcare System, MA (W.N.).
Wong PT; Department of Pharmacology, National University of Singapore (P.T.H.W).
Cool SM; Institute of Medical Biology, Glycotherapeutics Group, A*STAR (S.J.C., R.A.A.S., S.M.C., V.N.).
Lo EH; Department of Radiology (S.J.C., E.E., K.H., E.M., S.G., E.H.L.), Massachusetts General Hospital, Harvard Medical School, Charlestown.; Department of Neurology (K.H., E.H.L.), Massachusetts General Hospital, Harvard Medical School, Charlestown.
Nurcombe V; Institute of Medical Biology, Glycotherapeutics Group, A*STAR (S.J.C., R.A.A.S., S.M.C., V.N.).
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Źródło :
Stroke [Stroke] 2020 Sep; Vol. 51 (9), pp. 2844-2853. Date of Electronic Publication: 2020 Aug 10.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Brain Ischemia/*drug therapy
Heparitin Sulfate/*therapeutic use
Stroke/*drug therapy
Vascular Endothelial Growth Factor A/*therapeutic use
Animals ; Blood-Brain Barrier/drug effects ; Cell Proliferation/drug effects ; Heparitin Sulfate/administration & dosage ; Infarction, Middle Cerebral Artery/prevention & control ; Injections, Intraventricular ; Ischemic Attack, Transient/drug therapy ; Ischemic Attack, Transient/physiopathology ; Male ; Neovascularization, Physiologic/drug effects ; Neural Stem Cells/drug effects ; Rats ; Rats, Sprague-Dawley ; Recovery of Function ; Vascular Endothelial Growth Factor A/administration & dosage ; Vascular Endothelial Growth Factor Receptor-2/metabolism
Czasopismo naukowe
Tytuł :
Thiel's embalming method with additional intra-cerebral ventricular formalin injection (TEIF) for cadaver training of head and brain surgery.
Autorzy :
Miyake S; Department of Neurosurgery, Yokohama City University, 3-9 Fukuura, Kanazawa, Yokohama, 2360004, Japan. .
Suenaga J; Department of Neurosurgery, Yokohama City University, 3-9 Fukuura, Kanazawa, Yokohama, 2360004, Japan.
Miyazaki R; Department of Neurosurgery, Yokohama City University, 3-9 Fukuura, Kanazawa, Yokohama, 2360004, Japan.
Sasame J; Department of Neurosurgery, Yokohama City University, 3-9 Fukuura, Kanazawa, Yokohama, 2360004, Japan.
Akimoto T; Department of Neurosurgery, Yokohama City University, 3-9 Fukuura, Kanazawa, Yokohama, 2360004, Japan.
Tanaka T; Department of Neurosurgery, Yokohama City University, 3-9 Fukuura, Kanazawa, Yokohama, 2360004, Japan.
Ohtake M; Department of Neurosurgery, Yokohama City University, 3-9 Fukuura, Kanazawa, Yokohama, 2360004, Japan.
Takase H; Department of Neurosurgery, Yokohama City University, 3-9 Fukuura, Kanazawa, Yokohama, 2360004, Japan.
Tateishi K; Department of Neurosurgery, Yokohama City University, 3-9 Fukuura, Kanazawa, Yokohama, 2360004, Japan.
Shimizu N; Department of Neurosurgery, Yokohama City University, 3-9 Fukuura, Kanazawa, Yokohama, 2360004, Japan.
Murata H; Department of Neurosurgery, Yokohama City University, 3-9 Fukuura, Kanazawa, Yokohama, 2360004, Japan.
Funakoshi K; Department of Neuroanatomy, Yokohama City University, 3-9 Fukuura, Kanazawa, Yokohama, 2360004, Japan.
Yamamoto T; Department of Neurosurgery, Yokohama City University, 3-9 Fukuura, Kanazawa, Yokohama, 2360004, Japan.
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Źródło :
Anatomical science international [Anat Sci Int] 2020 Sep; Vol. 95 (4), pp. 564-570. Date of Electronic Publication: 2020 Apr 27.
Typ publikacji :
Journal Article
MeSH Terms :
Brain*
Cadaver*
Elasticity*
Education, Medical/*methods
Embalming/*methods
Formaldehyde/*administration & dosage
General Surgery/*education
Neurosurgery/*education
Aged ; Aged, 80 and over ; Animals ; Female ; Humans ; Injections, Intraventricular ; Male ; Rats
Czasopismo naukowe
Tytuł :
Neonatal ventriculitis: a case series and review of literature.
Autorzy :
Bhat RR; Senior Resident, Department of Pediatrics, University College of Medical Sciences and Guru Tegh Bahadur Hospital, Delhi, India.
Batra P; Professor, Department of Pediatrics, University College of Medical Sciences and Guru Tegh Bahadur Hospital, Delhi, India.
Sachan R; Associate Professor, Department of Pediatrics, University College of Medical Sciences and Guru Tegh Bahadur Hospital, Delhi, India.
Singh G; Consultant, Department of Neurosurgery, University College of Medical Sciences and Guru Tegh Bahadur Hospital, Delhi, India.
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Źródło :
Tropical doctor [Trop Doct] 2020 Jul; Vol. 50 (3), pp. 266-270. Date of Electronic Publication: 2020 May 31.
Typ publikacji :
Case Reports; Journal Article; Review
MeSH Terms :
Cerebral Ventriculitis/*diagnosis
Cerebral Ventriculitis/*therapy
Administration, Intravenous ; Anti-Bacterial Agents/administration & dosage ; Cerebral Ventriculitis/etiology ; Drainage/adverse effects ; Female ; Humans ; Infant, Newborn ; Injections, Intraventricular/adverse effects ; Male ; Meningitis/complications ; Meningitis/drug therapy
Czasopismo naukowe
Tytuł :
Hypothalamic tanycytes generate acute hyperphagia through activation of the arcuate neuronal network.
Autorzy :
Bolborea M; School of Life Sciences, University of Warwick, Coventry CV4 7AL, United Kingdom .
Pollatzek E; School of Life Sciences, University of Warwick, Coventry CV4 7AL, United Kingdom.
Benford H; School of Life Sciences, University of Warwick, Coventry CV4 7AL, United Kingdom.
Sotelo-Hitschfeld T; School of Life Sciences, University of Warwick, Coventry CV4 7AL, United Kingdom.
Dale N; School of Life Sciences, University of Warwick, Coventry CV4 7AL, United Kingdom .
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Jun 23; Vol. 117 (25), pp. 14473-14481. Date of Electronic Publication: 2020 Jun 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Arcuate Nucleus of Hypothalamus/*physiopathology
Ependymoglial Cells/*physiology
Hyperphagia/*physiopathology
Neurons/*physiology
Agouti-Related Protein/metabolism ; Animals ; Appetite/physiology ; Arcuate Nucleus of Hypothalamus/cytology ; Arcuate Nucleus of Hypothalamus/diagnostic imaging ; Channelrhodopsins/genetics ; Channelrhodopsins/metabolism ; Energy Metabolism/physiology ; Feeding Behavior/physiology ; Female ; Genes, Reporter ; Injections, Intraventricular ; Male ; Mice ; Mice, Transgenic ; Models, Animal ; Nerve Net/physiology ; Neuropeptide Y/metabolism ; Optical Imaging ; Optogenetics ; Patch-Clamp Techniques ; Pro-Opiomelanocortin/metabolism ; Stereotaxic Techniques
Czasopismo naukowe
Tytuł :
Let-7b-5p promotes electroacupuncture tolerance by downregulating Penk1 gene in CFA-induced inflammatory nociception rats.
Autorzy :
Zhang Q; College of Veterinary Medicine, Huazhong Agricultural University, No.1, Shizishan Street, Hongshan District, Wuhan, Hubei 430070, PR China. Electronic address: .
Liu A; College of Veterinary Medicine, Huazhong Agricultural University, No.1, Shizishan Street, Hongshan District, Wuhan, Hubei 430070, PR China. Electronic address: .
Abouelfetouh MM; College of Veterinary Medicine, Huazhong Agricultural University, No.1, Shizishan Street, Hongshan District, Wuhan, Hubei 430070, PR China. Electronic address: .
Ma N; College of Veterinary Medicine, Huazhong Agricultural University, No.1, Shizishan Street, Hongshan District, Wuhan, Hubei 430070, PR China.
Li M; College of Veterinary Medicine, Huazhong Agricultural University, No.1, Shizishan Street, Hongshan District, Wuhan, Hubei 430070, PR China.
Chen S; College of Veterinary Medicine, Huazhong Agricultural University, No.1, Shizishan Street, Hongshan District, Wuhan, Hubei 430070, PR China.
Ding M; College of Veterinary Medicine, Huazhong Agricultural University, No.1, Shizishan Street, Hongshan District, Wuhan, Hubei 430070, PR China. Electronic address: .
Ding Y; College of Veterinary Medicine, Huazhong Agricultural University, No.1, Shizishan Street, Hongshan District, Wuhan, Hubei 430070, PR China. Electronic address: .
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Źródło :
Gene [Gene] 2020 Jun 05; Vol. 742, pp. 144583. Date of Electronic Publication: 2020 Mar 14.
Typ publikacji :
Journal Article
MeSH Terms :
Electroacupuncture*
Enkephalins/*genetics
MicroRNAs/*metabolism
Nociceptive Pain/*therapy
Protein Precursors/*genetics
Animals ; Antagomirs/administration & dosage ; Disease Models, Animal ; Down-Regulation ; Female ; Freund's Adjuvant/administration & dosage ; Freund's Adjuvant/immunology ; Humans ; Injections, Intraventricular ; MicroRNAs/agonists ; MicroRNAs/antagonists & inhibitors ; Nociception/drug effects ; Nociceptive Pain/diagnosis ; Nociceptive Pain/genetics ; Nociceptive Pain/immunology ; Pain Threshold/drug effects ; Rats
Czasopismo naukowe
Tytuł :
Preventing Morphine-Seeking Behavior through the Re-Engineering of Vincamine's Biological Activity.
Autorzy :
Norwood VM 4th; Department of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, Florida 32610, United States.; Center for Natural Products, Drug Discovery & Development (CNPD3), College of Pharmacy, University of Florida, Gainesville, Florida 32610, United States.
Brice-Tutt AC; Department of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, Florida 32610, United States.; Center for Natural Products, Drug Discovery & Development (CNPD3), College of Pharmacy, University of Florida, Gainesville, Florida 32610, United States.
Eans SO; Department of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, Florida 32610, United States.; Center for Natural Products, Drug Discovery & Development (CNPD3), College of Pharmacy, University of Florida, Gainesville, Florida 32610, United States.
Stacy HM; Department of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, Florida 32610, United States.; Center for Natural Products, Drug Discovery & Development (CNPD3), College of Pharmacy, University of Florida, Gainesville, Florida 32610, United States.
Shi G; Department of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, Florida 32610, United States.; Center for Natural Products, Drug Discovery & Development (CNPD3), College of Pharmacy, University of Florida, Gainesville, Florida 32610, United States.
Ratnayake R; Department of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, Florida 32610, United States.; Center for Natural Products, Drug Discovery & Development (CNPD3), College of Pharmacy, University of Florida, Gainesville, Florida 32610, United States.
Rocca JR; Department of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, Florida 32610, United States.; McKnight Brain Institute, University of Florida, Gainesville, Florida 32610, United States.
Abboud KA; Department of Chemistry, University of Florida, Gainesville, Florida 32610, United States.
Li C; Department of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, Florida 32610, United States.; Center for Natural Products, Drug Discovery & Development (CNPD3), College of Pharmacy, University of Florida, Gainesville, Florida 32610, United States.
Luesch H; Department of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, Florida 32610, United States.; Center for Natural Products, Drug Discovery & Development (CNPD3), College of Pharmacy, University of Florida, Gainesville, Florida 32610, United States.
McLaughlin JP; Department of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, Florida 32610, United States.; Center for Natural Products, Drug Discovery & Development (CNPD3), College of Pharmacy, University of Florida, Gainesville, Florida 32610, United States.
Huigens RW 3rd; Department of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, Florida 32610, United States.; Center for Natural Products, Drug Discovery & Development (CNPD3), College of Pharmacy, University of Florida, Gainesville, Florida 32610, United States.
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Źródło :
Journal of medicinal chemistry [J Med Chem] 2020 May 28; Vol. 63 (10), pp. 5119-5138. Date of Electronic Publication: 2020 Mar 23.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Chemical Engineering/*methods
Drug-Seeking Behavior/*drug effects
Morphine/*administration & dosage
Vincamine/*administration & dosage
Vincamine/*chemical synthesis
Animals ; Drug-Seeking Behavior/physiology ; Injections, Intraperitoneal ; Injections, Intraventricular ; Male ; Mice ; Mice, Inbred C57BL ; Opioid-Related Disorders/drug therapy ; Opioid-Related Disorders/metabolism ; Orexin Receptor Antagonists/administration & dosage ; Orexin Receptor Antagonists/chemical synthesis ; Orexin Receptor Antagonists/metabolism ; Orexin Receptors/metabolism ; Protein Structure, Secondary ; Vincamine/metabolism
Czasopismo naukowe
Tytuł :
Locoregionally administered B7-H3-targeted CAR T cells for treatment of atypical teratoid/rhabdoid tumors.
Autorzy :
Theruvath J; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA.
Sotillo E; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA.
Mount CW; Department of Neurology, Stanford University School of Medicine, Stanford, CA, USA.
Graef CM; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA.
Delaidelli A; Department of Molecular Oncology, British Columbia Cancer Research Centre, Vancouver, British Columbia, Canada.
Heitzeneder S; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA.
Labanieh L; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA.; Department of Bioengineering, Stanford University, Stanford, CA, USA.
Dhingra S; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA.
Leruste A; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA.
Majzner RG; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA.; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA, USA.
Xu P; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA.
Mueller S; Department of Neurology, University of California San Francisco, San Francisco, CA, USA.; Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA.; Department of Pediatrics, University of California San Francisco, San Francisco, CA, USA.
Yecies DW; Department of Neurosurgery, Stanford University School of Medicine, Stanford, CA, USA.
Finetti MA; Wolfson Childhood Cancer Research Centre, Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, UK.
Williamson D; Wolfson Childhood Cancer Research Centre, Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, UK.
Johann PD; Hopp Children's Cancer Center Heidelberg, Heidelberg, Germany.; Division of Pediatric Neurooncology, German Cancer Research Center and German Cancer Consortium, Heidelberg, Germany.; Department of Pediatric Hematology and Oncology, Heidelberg University Hospital, Heidelberg, Germany.
Kool M; Hopp Children's Cancer Center Heidelberg, Heidelberg, Germany.; Division of Pediatric Neurooncology, German Cancer Research Center and German Cancer Consortium, Heidelberg, Germany.
Pfister S; Hopp Children's Cancer Center Heidelberg, Heidelberg, Germany.; Division of Pediatric Neurooncology, German Cancer Research Center and German Cancer Consortium, Heidelberg, Germany.; Department of Pediatric Hematology and Oncology, Heidelberg University Hospital, Heidelberg, Germany.
Hasselblatt M; Institute of Neuropathology, Münster University Hospital, Münster, Germany.
Frühwald MC; University Children's Hospital Augsburg, Swabian Children's Cancer Center, Augsburg, Germany.; EU-RHAB Registry Center, Augsburg, Germany.
Delattre O; Paris Sciences Lettres Research University, INSERM U830, Paris, France.; Paris Sciences Lettres Research University, SIREDO: Care, Innovation and Research for Children, Adolescents and Young Adults with Cancer, Institut Curie, Paris, France.
Surdez D; Paris Sciences Lettres Research University, INSERM U830, Paris, France.; Paris Sciences Lettres Research University, SIREDO: Care, Innovation and Research for Children, Adolescents and Young Adults with Cancer, Institut Curie, Paris, France.
Bourdeaut F; Paris Sciences Lettres Research University, INSERM U830, Paris, France.; Paris Sciences Lettres Research University, SIREDO: Care, Innovation and Research for Children, Adolescents and Young Adults with Cancer, Institut Curie, Paris, France.
Puget S; Paris University, Necker-Enfants Malades Hospital, Department of Neurosurgery, Assistance Publique-Hôpitaux de Paris, Paris, France.
Zaidi S; Paris Sciences Lettres Research University, INSERM U830, Paris, France.; Paris Sciences Lettres Research University, SIREDO: Care, Innovation and Research for Children, Adolescents and Young Adults with Cancer, Institut Curie, Paris, France.
Mitra SS; Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Cheshier S; Division of Pediatric Neurosurgery, Department of Neurosurgery, Primary Children's Hospital and Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.
Sorensen PH; Department of Molecular Oncology, British Columbia Cancer Research Centre, Vancouver, British Columbia, Canada.
Monje M; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA.; Department of Neurology, Stanford University School of Medicine, Stanford, CA, USA.; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA, USA.; Department of Neurosurgery, Stanford University School of Medicine, Stanford, CA, USA.; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.; Stanford Institute for Stem Cell and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Mackall CL; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA. .; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA, USA. .; Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA. .
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Źródło :
Nature medicine [Nat Med] 2020 May; Vol. 26 (5), pp. 712-719. Date of Electronic Publication: 2020 Apr 27.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
B7 Antigens/*immunology
Brain Neoplasms/*therapy
Cancer Vaccines/*administration & dosage
Immunotherapy, Adoptive/*methods
Rhabdoid Tumor/*therapy
Teratoma/*therapy
Adult ; Animals ; Brain/drug effects ; Brain/immunology ; Brain/pathology ; Brain Neoplasms/immunology ; Brain Neoplasms/pathology ; Cells, Cultured ; Child, Preschool ; Female ; Fetus/pathology ; Humans ; Infant ; Injections, Intraventricular ; Mice ; Mice, Inbred NOD ; Mice, SCID ; Receptors, Chimeric Antigen/administration & dosage ; Receptors, Chimeric Antigen/genetics ; Receptors, Chimeric Antigen/immunology ; Rhabdoid Tumor/immunology ; Rhabdoid Tumor/pathology ; T-Lymphocytes/immunology ; T-Lymphocytes/metabolism ; T-Lymphocytes/transplantation ; Teratoma/immunology ; Teratoma/pathology ; Xenograft Model Antitumor Assays
SCR Disease Name :
Teratoid Tumor, Atypical
Czasopismo naukowe
Tytuł :
Locoregional delivery of CAR T cells to the cerebrospinal fluid for treatment of metastatic medulloblastoma and ependymoma.
Autorzy :
Donovan LK; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.
Delaidelli A; Department of Molecular Oncology, British Columbia Cancer Research Centre, Vancouver, British Columbia, Canada.
Joseph SK; Texas Children's Hospital, Baylor College of Medicine, Houston, TX, USA.; Centre for Cell and Gene Therapy, Texas Children's Hospital, Houston Methodist Hospital, Baylor College of Medicine, Houston, TX, USA.
Bielamowicz K; Texas Children's Hospital, Baylor College of Medicine, Houston, TX, USA.; Centre for Cell and Gene Therapy, Texas Children's Hospital, Houston Methodist Hospital, Baylor College of Medicine, Houston, TX, USA.
Fousek K; Texas Children's Hospital, Baylor College of Medicine, Houston, TX, USA.; Centre for Cell and Gene Therapy, Texas Children's Hospital, Houston Methodist Hospital, Baylor College of Medicine, Houston, TX, USA.
Holgado BL; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.
Manno A; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.
Srikanthan D; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.
Gad AZ; Texas Children's Hospital, Baylor College of Medicine, Houston, TX, USA.; Centre for Cell and Gene Therapy, Texas Children's Hospital, Houston Methodist Hospital, Baylor College of Medicine, Houston, TX, USA.
Van Ommeren R; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.
Przelicki D; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.
Richman C; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.
Ramaswamy V; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Division of Haematology/Oncology, Department of Paediatrics, The Hospital for Sick Children, Toronto, Ontario, Canada.
Daniels C; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.
Pallota JG; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.
Douglas T; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.
Joynt ACM; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.
Haapasalo J; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.
Nor C; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.
Vladoiu MC; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.
Kuzan-Fischer CM; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.
Garzia L; Cancer Research Program, McGill University Health Centre Research Institute, Montreal, Quebec, Canada.
Mack SC; Brain Tumour Program, Children's Cancer Centre and Department of Paediatrics, Baylor College of Medicine, Houston, TX, USA.
Varadharajan S; Brain Tumour Program, Children's Cancer Centre and Department of Paediatrics, Baylor College of Medicine, Houston, TX, USA.
Baker ML; Centre for Cell and Gene Therapy, Texas Children's Hospital, Houston Methodist Hospital, Baylor College of Medicine, Houston, TX, USA.
Hendrikse L; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.
Ly M; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.
Kharas K; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.
Balin P; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.
Wu X; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.
Qin L; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.
Huang N; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.
Stucklin AG; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.
Morrissy AS; Department of Biochemistry & Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.; Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.
Cavalli FMG; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.
Luu B; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.
Suarez R; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.
De Antonellis P; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.
Michealraj A; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.
Rastan A; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.
Hegde M; Texas Children's Hospital, Baylor College of Medicine, Houston, TX, USA.; Centre for Cell and Gene Therapy, Texas Children's Hospital, Houston Methodist Hospital, Baylor College of Medicine, Houston, TX, USA.
Komosa M; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.
Sirbu O; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.
Kumar SA; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.
Abdullaev Z; Laboratory of Pathology, National Cancer Institute Centre for Cancer Research, Bethesda, MD, USA.
Faria CC; Division of Neurosurgery, Centro Hospitalar Lisboa Norte, Hospital de Santa Maria, Lisbon, Portugal.
Yip S; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Hukin J; Division of Neurology, British Columbia Children's Hospital, Vancouver, British Columbia, Canada.
Tabori U; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.
Hawkins C; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.
Aldape K; Laboratory of Pathology, National Cancer Institute Centre for Cancer Research, Bethesda, MD, USA.
Daugaard M; Department of Urologic Sciences, University of British Columbia, Vancouver, British Columbia, Canada.; Vancouver Prostate Centre, Vancouver Coastal Health Research Institute, Vancouver, British Columbia, Canada.
Maris JM; Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Centre for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Sorensen PH; Department of Molecular Oncology, British Columbia Cancer Research Centre, Vancouver, British Columbia, Canada.
Ahmed N; Texas Children's Hospital, Baylor College of Medicine, Houston, TX, USA.; Centre for Cell and Gene Therapy, Texas Children's Hospital, Houston Methodist Hospital, Baylor College of Medicine, Houston, TX, USA.
Taylor MD; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada. .; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada. .; Division of Neurosurgery, The Hospital for Sick Children, Toronto, Ontario, Canada. .; Department of Surgery, Department of Laboratory Medicine and Pathobiology, and Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada. .
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Źródło :
Nature medicine [Nat Med] 2020 May; Vol. 26 (5), pp. 720-731. Date of Electronic Publication: 2020 Apr 27.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Validation Study
MeSH Terms :
Brain Neoplasms/*therapy
Cancer Vaccines/*administration & dosage
Cerebrospinal Fluid/*drug effects
Ependymoma/*therapy
Immunotherapy, Adoptive/*methods
Medulloblastoma/*therapy
Animals ; Brain Neoplasms/cerebrospinal fluid ; Brain Neoplasms/immunology ; Brain Neoplasms/pathology ; Cerebellar Neoplasms/cerebrospinal fluid ; Cerebellar Neoplasms/immunology ; Cerebellar Neoplasms/pathology ; Cerebellar Neoplasms/therapy ; Cerebrospinal Fluid/immunology ; Child ; Child, Preschool ; Drug Delivery Systems/methods ; Ependymoma/cerebrospinal fluid ; Ependymoma/immunology ; Ependymoma/pathology ; Female ; HEK293 Cells ; Humans ; Infant ; Injections, Intraventricular ; Male ; Medulloblastoma/cerebrospinal fluid ; Medulloblastoma/immunology ; Medulloblastoma/pathology ; Mice ; Neoplasm Metastasis ; Receptors, Chimeric Antigen/administration & dosage ; Receptors, Chimeric Antigen/genetics ; Receptors, Chimeric Antigen/immunology ; T-Lymphocytes/immunology ; T-Lymphocytes/metabolism ; T-Lymphocytes/transplantation ; Treatment Outcome ; Tumor Cells, Cultured ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Assessing Cerebrospinal Fluid Flow Dynamics in Pediatric Patients with Central Nervous System Tumors Treated with Intraventricular Radioimmunotherapy.
Autorzy :
Kramer K; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York; and .
Donzelli M; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York; and.
Nwora E; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York; and.
Pandit-Taskar N; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.
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Źródło :
Journal of nuclear medicine : official publication, Society of Nuclear Medicine [J Nucl Med] 2020 May; Vol. 61 (5), pp. 662-664. Date of Electronic Publication: 2020 Jan 31.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Hydrodynamics*
Radioimmunotherapy*
Central Nervous System Neoplasms/*physiopathology
Central Nervous System Neoplasms/*radiotherapy
Cerebrospinal Fluid/*metabolism
Central Nervous System Neoplasms/cerebrospinal fluid ; Humans ; Injections, Intraventricular ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Prx2 (Peroxiredoxin 2) as a Cause of Hydrocephalus After Intraventricular Hemorrhage.
Autorzy :
Tan X; From the Department of Neurosurgery, University of Michigan, Ann Arbor (X.T., J.C., R.F.K., G.X., Y.H.).; Department of Neurosurgery, The 2nd Affiliated Hospital, Zhejiang University, Hangzhou, China (X.T., J.C.).
Chen J; From the Department of Neurosurgery, University of Michigan, Ann Arbor (X.T., J.C., R.F.K., G.X., Y.H.).; Department of Neurosurgery, The 2nd Affiliated Hospital, Zhejiang University, Hangzhou, China (X.T., J.C.).
Keep RF; From the Department of Neurosurgery, University of Michigan, Ann Arbor (X.T., J.C., R.F.K., G.X., Y.H.).
Xi G; From the Department of Neurosurgery, University of Michigan, Ann Arbor (X.T., J.C., R.F.K., G.X., Y.H.).
Hua Y; From the Department of Neurosurgery, University of Michigan, Ann Arbor (X.T., J.C., R.F.K., G.X., Y.H.).
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Źródło :
Stroke [Stroke] 2020 May; Vol. 51 (5), pp. 1578-1586. Date of Electronic Publication: 2020 Apr 13.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Cerebral Intraventricular Hemorrhage/*metabolism
Choroid Plexus/*metabolism
Hydrocephalus/*metabolism
Inflammation/*metabolism
Macrophages/*metabolism
Peroxiredoxins/*metabolism
Animals ; Anti-Inflammatory Agents/pharmacology ; Cerebral Intraventricular Hemorrhage/complications ; Choroid Plexus/drug effects ; Choroid Plexus/pathology ; Disease Models, Animal ; Ependyma/drug effects ; Ependyma/pathology ; Female ; Hydrocephalus/etiology ; Hylobatidae ; Inflammation/pathology ; Injections, Intraventricular ; Macrophage Activation/drug effects ; Macrophages/drug effects ; Macrophages/pathology ; Male ; Minocycline/pharmacology ; Neutrophils/drug effects ; Neutrophils/pathology ; Peroxiredoxins/antagonists & inhibitors ; Peroxiredoxins/pharmacology ; Quinoxalines/pharmacology ; Rats ; Rats, Sprague-Dawley
SCR Organism :
Nomascus concolor
Czasopismo naukowe
Tytuł :
Recombinant OX40 attenuates neuronal apoptosis through OX40-OX40L/PI3K/AKT signaling pathway following subarachnoid hemorrhage in rats.
Autorzy :
Wu LY; Department of Neurosurgery, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing 210008, China; Department of Physiology and Pharmacology, School of Medicine, Loma Linda University, Loma Linda, CA 92354, United States.
Enkhjargal B; Department of Physiology and Pharmacology, School of Medicine, Loma Linda University, Loma Linda, CA 92354, United States.
Xie ZY; Department of Physiology and Pharmacology, School of Medicine, Loma Linda University, Loma Linda, CA 92354, United States.
Travis ZD; Department of Physiology and Pharmacology, School of Medicine, Loma Linda University, Loma Linda, CA 92354, United States.
Sun CM; Department of Physiology and Pharmacology, School of Medicine, Loma Linda University, Loma Linda, CA 92354, United States.
Zhou KR; Department of Physiology and Pharmacology, School of Medicine, Loma Linda University, Loma Linda, CA 92354, United States.
Zhang TY; Department of Physiology and Pharmacology, School of Medicine, Loma Linda University, Loma Linda, CA 92354, United States.
Zhu QQ; Department of Physiology and Pharmacology, School of Medicine, Loma Linda University, Loma Linda, CA 92354, United States.
Hang CH; Department of Neurosurgery, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing 210008, China. Electronic address: .
Zhang JH; Department of Physiology and Pharmacology, School of Medicine, Loma Linda University, Loma Linda, CA 92354, United States; Department of Physiology and Pharmacology, Department of Anesthesiology and Department of Neurosurgery, School of Medicine, Loma Linda University, Loma Linda, CA 92354, United States. Electronic address: .
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Źródło :
Experimental neurology [Exp Neurol] 2020 Apr; Vol. 326, pp. 113179. Date of Electronic Publication: 2020 Jan 10.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Apoptosis/*drug effects
Neurons/*drug effects
Receptors, OX40/*therapeutic use
Signal Transduction/*drug effects
Signal Transduction/*genetics
Subarachnoid Hemorrhage/*drug therapy
Subarachnoid Hemorrhage/*genetics
Animals ; Apoptosis Regulatory Proteins/biosynthesis ; Apoptosis Regulatory Proteins/genetics ; Injections, Intraventricular ; Male ; Membrane Glycoproteins/antagonists & inhibitors ; Oncogene Protein v-akt/antagonists & inhibitors ; Phosphatidylinositol 3-Kinases/genetics ; Protein Kinase Inhibitors/therapeutic use ; RNA, Small Interfering/therapeutic use ; Rats ; Rats, Sprague-Dawley ; Receptors, OX40/pharmacology ; Recombinant Proteins/pharmacology ; Recombinant Proteins/therapeutic use ; Tumor Necrosis Factors
Czasopismo naukowe
Tytuł :
Cannabidiol-induced panicolytic-like effects and fear-induced antinociception impairment: the role of the CB 1 receptor in the ventromedial hypothalamus.
Autorzy :
Khan AU; Laboratory of Neuroanatomy and Neuropsychobiology, Department of Pharmacology, Ribeirão Preto Medical School of the University of São Paulo (FMRP-USP), Av. Bandeirantes, 3900, Ribeirão Preto, São Paulo, 14049-900, Brazil.; Department of Eastern Medicine and Surgery, School of Medical and Health Sciences, The University of Poonch Rawalakot, Hajira Road, Shamsabad, Rawalakot, Azad Jammu & Kashmir, 12350, Pakistan.; Neurobiology of Emotions (NAP-USP-NuPNE) Research Centre, Ribeirão Preto School of Medicine of the University of São Paulo (FMRP-USP), Av. Bandeirantes, 3900, Ribeirão Preto, São Paulo, 14049-900, Brazil.
Falconi-Sobrinho LL; Laboratory of Neuroanatomy and Neuropsychobiology, Department of Pharmacology, Ribeirão Preto Medical School of the University of São Paulo (FMRP-USP), Av. Bandeirantes, 3900, Ribeirão Preto, São Paulo, 14049-900, Brazil.; Neurobiology of Emotions (NAP-USP-NuPNE) Research Centre, Ribeirão Preto School of Medicine of the University of São Paulo (FMRP-USP), Av. Bandeirantes, 3900, Ribeirão Preto, São Paulo, 14049-900, Brazil.; Behavioural Neurosciences Institute (INeC), Avenida do Café, 2450, Ribeirão Preto, São Paulo, 4220-030, Brazil.
Dos Anjos-Garcia T; Laboratory of Neuroanatomy and Neuropsychobiology, Department of Pharmacology, Ribeirão Preto Medical School of the University of São Paulo (FMRP-USP), Av. Bandeirantes, 3900, Ribeirão Preto, São Paulo, 14049-900, Brazil.; Neurobiology of Emotions (NAP-USP-NuPNE) Research Centre, Ribeirão Preto School of Medicine of the University of São Paulo (FMRP-USP), Av. Bandeirantes, 3900, Ribeirão Preto, São Paulo, 14049-900, Brazil.
de Fátima Dos Santos Sampaio M; Laboratory of Neuroanatomy and Neuropsychobiology, Department of Pharmacology, Ribeirão Preto Medical School of the University of São Paulo (FMRP-USP), Av. Bandeirantes, 3900, Ribeirão Preto, São Paulo, 14049-900, Brazil.
de Souza Crippa JA; Department of Neuroscience and Behavioural Sciences, Division of Psychiatry, Ribeirão Preto Medical School of the University of São Paulo (FMRP-USP), Av. Bandeirantes, 3900, Ribeirão Preto, São Paulo, 14049-900, Brazil.
Menescal-de-Oliveira L; Neurobiology of Emotions (NAP-USP-NuPNE) Research Centre, Ribeirão Preto School of Medicine of the University of São Paulo (FMRP-USP), Av. Bandeirantes, 3900, Ribeirão Preto, São Paulo, 14049-900, Brazil.; Laboratory of Neurophysiology, Department of Physiology, Ribeirão Preto Medical School of the University of São Paulo, Av. Bandeirantes, 3900, Ribeirão Preto, São Paulo, 14049-900, Brazil.
Coimbra NC; Laboratory of Neuroanatomy and Neuropsychobiology, Department of Pharmacology, Ribeirão Preto Medical School of the University of São Paulo (FMRP-USP), Av. Bandeirantes, 3900, Ribeirão Preto, São Paulo, 14049-900, Brazil. .; Neurobiology of Emotions (NAP-USP-NuPNE) Research Centre, Ribeirão Preto School of Medicine of the University of São Paulo (FMRP-USP), Av. Bandeirantes, 3900, Ribeirão Preto, São Paulo, 14049-900, Brazil. .; Behavioural Neurosciences Institute (INeC), Avenida do Café, 2450, Ribeirão Preto, São Paulo, 4220-030, Brazil. .
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Źródło :
Psychopharmacology [Psychopharmacology (Berl)] 2020 Apr; Vol. 237 (4), pp. 1063-1079. Date of Electronic Publication: 2020 Jan 09.
Typ publikacji :
Journal Article
MeSH Terms :
Cannabidiol/*toxicity
Fear/*physiology
Pain Measurement/*methods
Panic Disorder/*metabolism
Receptor, Cannabinoid, CB1/*metabolism
Ventromedial Hypothalamic Nucleus/*metabolism
Animals ; Cannabidiol/administration & dosage ; Fear/drug effects ; Fear/psychology ; Injections, Intraventricular ; Male ; N-Methylaspartate/administration & dosage ; Pain Measurement/drug effects ; Pain Measurement/psychology ; Panic Disorder/chemically induced ; Piperidines/administration & dosage ; Pyrazoles/administration & dosage ; Rats ; Rats, Wistar ; Receptor, Cannabinoid, CB1/antagonists & inhibitors ; Ventromedial Hypothalamic Nucleus/drug effects
Czasopismo naukowe
Tytuł :
Intraventricular CNS treatment with Colistin-Tigecycline combination: A case series.
Autorzy :
Tsolaki V; Intensive Care Unit, University Hospital of Larisa, University of Thessaly Medical School, Biopolis 41110, Greece. Electronic address: .
Karvouniaris M; Intensive Care Unit, University Hospital of Larisa, University of Thessaly Medical School, Biopolis 41110, Greece.
Manoulakas E; Intensive Care Unit, University Hospital of Larisa, University of Thessaly Medical School, Biopolis 41110, Greece.
Kotlia P; Intensive Care Unit, University Hospital of Larisa, University of Thessaly Medical School, Biopolis 41110, Greece.
Karadontas V; Intensive Care Unit, University Hospital of Larisa, University of Thessaly Medical School, Biopolis 41110, Greece.
Fotakopoulos G; Neurosurgical Department, University Hospital of Larisa, University of Thessaly Medical School, Biopolis 41110, Greece.
Zakynthinos E; Intensive Care Unit, University Hospital of Larisa, University of Thessaly Medical School, Biopolis 41110, Greece.
Makris D; Intensive Care Unit, University Hospital of Larisa, University of Thessaly Medical School, Biopolis 41110, Greece.
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Źródło :
Journal of critical care [J Crit Care] 2018 Oct; Vol. 47, pp. 338-341. Date of Electronic Publication: 2018 Jul 30.
Typ publikacji :
Case Reports; Letter
MeSH Terms :
Injections, Intraventricular*
Acinetobacter Infections/*drug therapy
Cerebral Ventriculitis/*drug therapy
Colistin/*administration & dosage
Klebsiella Infections/*drug therapy
Tigecycline/*administration & dosage
Acinetobacter baumannii/drug effects ; Administration, Intravenous ; Anti-Bacterial Agents/therapeutic use ; Central Nervous System/drug effects ; Drug Resistance, Multiple, Bacterial/drug effects ; Drug Therapy, Combination ; Encephalitis ; Female ; Humans ; Infusions, Intraventricular ; Klebsiella pneumoniae/drug effects ; Male ; Middle Aged ; Research Design ; Young Adult
Raport
Tytuł :
In vivo distribution of U87MG cells injected into the lateral ventricle of rats with spinal cord injury.
Autorzy :
Won JS; Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, Seoul, South Korea.; Single Cell Network Research Center, Sungkyunkwan University School of Medicine, Suwon, South Korea.; Stem Cell and Regenerative Medicine Center, Research Institute for Future Medicine, Samsung Medical Center, Seoul, South Korea.
Nam H; Single Cell Network Research Center, Sungkyunkwan University School of Medicine, Suwon, South Korea.; Stem Cell and Regenerative Medicine Center, Research Institute for Future Medicine, Samsung Medical Center, Seoul, South Korea.; Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.
Lee HW; Single Cell Network Research Center, Sungkyunkwan University School of Medicine, Suwon, South Korea.; Department of Anatomy & Cell Biology, Sungkyunkwan University School of Medicine, Suwon, South Korea.
Hwang JY; Single Cell Network Research Center, Sungkyunkwan University School of Medicine, Suwon, South Korea.; Stem Cell and Regenerative Medicine Center, Research Institute for Future Medicine, Samsung Medical Center, Seoul, South Korea.; Department of Anatomy & Cell Biology, Sungkyunkwan University School of Medicine, Suwon, South Korea.
Noh YJ; Single Cell Network Research Center, Sungkyunkwan University School of Medicine, Suwon, South Korea.; Stem Cell and Regenerative Medicine Center, Research Institute for Future Medicine, Samsung Medical Center, Seoul, South Korea.; Department of Anatomy & Cell Biology, Sungkyunkwan University School of Medicine, Suwon, South Korea.
Nam DH; Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, Seoul, South Korea.; Stem Cell and Regenerative Medicine Center, Research Institute for Future Medicine, Samsung Medical Center, Seoul, South Korea.; Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.
Lee SH; Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, Seoul, South Korea.; Stem Cell and Regenerative Medicine Center, Research Institute for Future Medicine, Samsung Medical Center, Seoul, South Korea.; Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.
Joo KM; Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, Seoul, South Korea.; Single Cell Network Research Center, Sungkyunkwan University School of Medicine, Suwon, South Korea.; Stem Cell and Regenerative Medicine Center, Research Institute for Future Medicine, Samsung Medical Center, Seoul, South Korea.; Department of Anatomy & Cell Biology, Sungkyunkwan University School of Medicine, Suwon, South Korea.
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Źródło :
PloS one [PLoS One] 2018 Aug 16; Vol. 13 (8), pp. e0202307. Date of Electronic Publication: 2018 Aug 16 (Print Publication: 2018).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell- and Tissue-Based Therapy*
Injections, Intraventricular*
Lateral Ventricles*
Spinal Cord Injuries/*therapy
Animals ; Cell Line, Tumor ; Cell Movement ; Disease Models, Animal ; Female ; Fluorescent Dyes ; Humans ; Magnetite Nanoparticles ; Optical Imaging ; Rats, Sprague-Dawley ; Spinal Cord/pathology ; Spinal Cord Injuries/pathology
Czasopismo naukowe
Tytuł :
Developing a newborn rat model of ventriculitis without concomitant bacteremia by intraventricular injection of K1 (-) Escherichia coli.
Autorzy :
Ahn SY; Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Chang YS; Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.; Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine, Seoul, Korea.
Sung DK; Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Kim YE; Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine, Seoul, Korea.
Park WS; Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.; Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine, Seoul, Korea.
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Źródło :
Pediatrics international : official journal of the Japan Pediatric Society [Pediatr Int] 2020 Mar; Vol. 62 (3), pp. 347-356.
Typ publikacji :
Journal Article
MeSH Terms :
Cerebral Ventriculitis/*microbiology
Escherichia coli/*pathogenicity
Escherichia coli Infections/*microbiology
Injections, Intraventricular/*methods
Meningitis, Bacterial/*microbiology
Animals ; Animals, Newborn ; Bacteremia/pathology ; Cerebral Ventriculitis/pathology ; Disease Models, Animal ; Escherichia coli Infections/pathology ; Humans ; Meningitis, Bacterial/pathology ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
MicroRNA-152 attenuates neuroinflammation in intracerebral hemorrhage by inhibiting thioredoxin interacting protein (TXNIP)-mediated NLRP3 inflammasome activation.
Autorzy :
Hu L; Department of Neurology, The First Affiliated Hospital of China Medical University, Shenyang 110000, People's Republic of China.
Zhang H; Department of Neurology, The First Affiliated Hospital Sun Yat-sen University, Guangzhou 510080, People's Republic of China.
Wang B; Department of Neurology, The First Affiliated Hospital of China Medical University, Shenyang 110000, People's Republic of China.
Ao Q; Department of Tissue Engineering, China Medical University, Shenyang 110122, People's Republic of China.
He Z; Department of Neurology, The First Affiliated Hospital of China Medical University, Shenyang 110000, People's Republic of China. Electronic address: .
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Źródło :
International immunopharmacology [Int Immunopharmacol] 2020 Mar; Vol. 80, pp. 106141. Date of Electronic Publication: 2020 Jan 23.
Typ publikacji :
Journal Article
MeSH Terms :
Carrier Proteins/*genetics
Cell Cycle Proteins/*genetics
Cerebral Intraventricular Hemorrhage/*genetics
Inflammasomes/*immunology
MicroRNAs/*metabolism
Thioredoxins/*genetics
Animals ; Carrier Proteins/metabolism ; Cell Cycle Proteins/metabolism ; Cell Line ; Cerebral Intraventricular Hemorrhage/chemically induced ; Cerebral Intraventricular Hemorrhage/immunology ; Cerebral Intraventricular Hemorrhage/pathology ; Cerebral Ventricles/immunology ; Cerebral Ventricles/pathology ; Coculture Techniques ; Disease Models, Animal ; Down-Regulation/immunology ; Gene Knockdown Techniques ; Hemin/immunology ; Humans ; Inflammasomes/metabolism ; Injections, Intraventricular ; Male ; Mice ; MicroRNAs/agonists ; MicroRNAs/antagonists & inhibitors ; Microbial Collagenase/administration & dosage ; Microbial Collagenase/toxicity ; Microglia ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; Neurons ; Protein Binding/genetics ; Protein Binding/immunology ; RNA, Small Interfering/metabolism ; Rats ; Thioredoxins/metabolism
Czasopismo naukowe
Tytuł :
Rostral intralaminar thalamic deep brain stimulation ameliorates memory deficits and dendritic regression in β-amyloid-infused rats.
Autorzy :
Tsai ST; Department of Neurosurgery, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation/Tzu Chi University, Hualien, Taiwan.; Institute of Medical Sciences, Tzu Chi University, Hualien, Taiwan.
Chen SY; Department of Neurosurgery, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation/Tzu Chi University, Hualien, Taiwan.; Institute of Medical Sciences, Tzu Chi University, Hualien, Taiwan.
Lin SZ; Department of Neurosurgery, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation/Tzu Chi University, Hualien, Taiwan.
Tseng GF; Department of Anatomy, College of Medicine, Tzu-Chi University, No. 701, Section 3, Jhongyang Road, Hualien, 970, Taiwan. .
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Źródło :
Brain structure & function [Brain Struct Funct] 2020 Mar; Vol. 225 (2), pp. 751-761. Date of Electronic Publication: 2020 Feb 08.
Typ publikacji :
Journal Article
MeSH Terms :
Alzheimer Disease/*physiopathology
Amyloid beta-Peptides/*toxicity
Dendrites/*physiology
Hippocampus/*physiology
Intralaminar Thalamic Nuclei/*physiology
Prefrontal Cortex/*physiology
Spatial Learning/*physiology
Spatial Memory/*physiology
Alzheimer Disease/pathology ; Amyloid beta-Peptides/administration & dosage ; Animals ; Dendrites/drug effects ; Disease Models, Animal ; Electric Stimulation ; Hippocampus/cytology ; Hippocampus/drug effects ; Injections, Intraventricular ; Intralaminar Thalamic Nuclei/drug effects ; Male ; Prefrontal Cortex/cytology ; Prefrontal Cortex/drug effects ; Rats, Wistar ; Spatial Learning/drug effects ; Spatial Memory/drug effects
Czasopismo naukowe

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