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Tytuł :
Beta-cell function is disrupted in patients with systemic lupus erythematosus.
Autorzy :
García-Dorta A; Division of Rheumatology, Hospital Universitario de Canarias, Tenerife, Spain.
Quevedo-Abeledo JC; Division of Rheumatology, Hospital Doctor Negrín, Las Palmas de Gran Canaria, Spain.
Rua-Figueroa Í; Division of Rheumatology, Hospital Doctor Negrín, Las Palmas de Gran Canaria, Spain.
de Vera-González AM; Division of Central Laboratory, Hospital Universitario de Canarias, Tenerife, Spain.
González-Delgado A; Division of Central Laboratory, Hospital Universitario de Canarias, Tenerife, Spain.
Medina-Vega L; Division of Central Laboratory, Hospital Universitario de Canarias, Tenerife, Spain.
González-Rivero AF; Division of Central Laboratory, Hospital Universitario de Canarias, Tenerife, Spain.
Francisco-Hernández F; Division of Rheumatology, Hospital Doctor Negrín, Las Palmas de Gran Canaria, Spain.
González-Gay MA; Division of Rheumatology, Hospital Universitario Marqués de Valdecilla, Universidad de Cantabria, Santander, Spain.; Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain.; Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Ferraz-Amaro I; Division of Rheumatology, Hospital Universitario de Canarias, Tenerife, Spain.
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Źródło :
Rheumatology (Oxford, England) [Rheumatology (Oxford)] 2021 Aug 02; Vol. 60 (8), pp. 3826-3833.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Insulin Secretion*
C-Peptide/*metabolism
Diabetes Mellitus/*metabolism
Insulin/*metabolism
Insulin-Secreting Cells/*metabolism
Lupus Erythematosus, Systemic/*metabolism
Proinsulin/*metabolism
Adult ; Female ; Glucocorticoids/therapeutic use ; Humans ; Insulin Resistance ; Lupus Erythematosus, Systemic/drug therapy ; Male ; Middle Aged
SCR Disease Name :
Hyperproinsulinemia
Czasopismo naukowe
Tytuł :
A radioligand receptor binding assay for measuring of insulin secreted by MIN6 cells after stimulation with glucose, arginine, ornithine, dopamine, and serotonin.
Autorzy :
Asai S; Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Flemingovo nám. 2, 116 10, Prague 6, Czech Republic.; Department of Biochemistry, Faculty of Science, Charles University, 12840, Prague 2, Czech Republic.
Žáková L; Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Flemingovo nám. 2, 116 10, Prague 6, Czech Republic.
Selicharová I; Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Flemingovo nám. 2, 116 10, Prague 6, Czech Republic.
Marek A; Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Flemingovo nám. 2, 116 10, Prague 6, Czech Republic.
Jiráček J; Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Flemingovo nám. 2, 116 10, Prague 6, Czech Republic. .
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Źródło :
Analytical and bioanalytical chemistry [Anal Bioanal Chem] 2021 Jul; Vol. 413 (17), pp. 4531-4543. Date of Electronic Publication: 2021 May 29.
Typ publikacji :
Journal Article
MeSH Terms :
Insulin Secretion*
Insulin/*analysis
Insulin/*metabolism
Animals ; Arginine/metabolism ; Cell Line ; Dopamine/metabolism ; Glucose/metabolism ; Humans ; Insulin-Secreting Cells/metabolism ; Islets of Langerhans/metabolism ; Mice ; Ornithine/metabolism ; Radioimmunoassay/methods ; Radioligand Assay/methods ; Rats ; Rats, Wistar ; Serotonin/metabolism
Czasopismo naukowe
Tytuł :
Tissue-specific expression of insulin receptor isoforms in obesity/type 2 diabetes mouse models.
Autorzy :
Moruzzi N; Department of Molecular Medicine and Surgery, The Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
Lazzeri-Barcelo F; Department of Molecular Medicine and Surgery, The Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
Valladolid-Acebes I; Department of Molecular Medicine and Surgery, The Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
Moede T; Department of Molecular Medicine and Surgery, The Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
Paschen M; Department of Molecular Medicine and Surgery, The Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
Leibiger B; Department of Molecular Medicine and Surgery, The Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
Berggren PO; Department of Molecular Medicine and Surgery, The Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
Leibiger IB; Department of Molecular Medicine and Surgery, The Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
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Źródło :
Journal of cellular and molecular medicine [J Cell Mol Med] 2021 May; Vol. 25 (10), pp. 4800-4813. Date of Electronic Publication: 2021 Mar 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation*
Insulin Resistance*
Diabetes Mellitus, Experimental/*pathology
Diabetes Mellitus, Type 2/*pathology
Obesity/*complications
Receptor, Insulin/*metabolism
Adipose Tissue/metabolism ; Adipose Tissue/pathology ; Alternative Splicing ; Animals ; Diabetes Mellitus, Experimental/etiology ; Diabetes Mellitus, Experimental/metabolism ; Diabetes Mellitus, Type 2/etiology ; Diabetes Mellitus, Type 2/metabolism ; Insulin/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Organ Specificity ; Protein Isoforms ; Receptor, Insulin/genetics ; Signal Transduction
Czasopismo naukowe
Tytuł :
Activation of Wnt/β-catenin signaling restores insulin sensitivity in insulin resistant neurons through transcriptional regulation of IRS-1.
Autorzy :
Tian S; Department of Neurology, Qilu Hospital of Shandong University, Jinan, China.; Brain Research Institute, Qilu Hospital of Shandong University, Jinan, China.
Tan S; Department of Neurology, Qilu Hospital of Shandong University, Jinan, China.; Brain Research Institute, Qilu Hospital of Shandong University, Jinan, China.
Jia W; NHC Key Laboratory of Otorhinolaryngology, Chinese Ministry of Health, Qilu Hospital of Shandong University, Jinan, China.
Zhao J; NHC Key Laboratory of Otorhinolaryngology, Chinese Ministry of Health, Qilu Hospital of Shandong University, Jinan, China.
Sun X; Brain Research Institute, Qilu Hospital of Shandong University, Jinan, China.; The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission, Qilu Hospital of Shandong University, Jinan, China.
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Źródło :
Journal of neurochemistry [J Neurochem] 2021 May; Vol. 157 (3), pp. 467-478. Date of Electronic Publication: 2020 Dec 31.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Insulin Resistance*
Insulin Receptor Substrate Proteins/*genetics
Insulin Receptor Substrate Proteins/*metabolism
Neurons/*drug effects
Neurons/*metabolism
Wnt Signaling Pathway/*drug effects
Animals ; Gene Expression Regulation ; Glucose/metabolism ; HEK293 Cells ; Humans ; Hypoglycemic Agents/pharmacology ; Insulin/pharmacology ; Primary Cell Culture ; Rats ; Rats, Sprague-Dawley ; Transcription Factor 4/genetics ; Up-Regulation ; beta Catenin/metabolism
Czasopismo naukowe
Tytuł :
Similar dietary regulation of IGF-1- and IGF-binding proteins by animal and plant protein in subjects with type 2 diabetes.
Autorzy :
Schüler R; Department of Clinical Nutrition, German Institute of Human Nutrition Potsdam-Rehbrücke (DIfE), 14558, Nuthetal, Germany.; German Center for Diabetes Research (DZD), 85764, München-Neuherberg, Germany.
Markova M; Department of Clinical Nutrition, German Institute of Human Nutrition Potsdam-Rehbrücke (DIfE), 14558, Nuthetal, Germany.; German Center for Diabetes Research (DZD), 85764, München-Neuherberg, Germany.
Osterhoff MA; Department of Clinical Nutrition, German Institute of Human Nutrition Potsdam-Rehbrücke (DIfE), 14558, Nuthetal, Germany.; German Center for Diabetes Research (DZD), 85764, München-Neuherberg, Germany.; Department of Endocrinology, Diabetes and Nutrition, Charité-Universitätsmedizin Berlin, Campus Benjamin Franklin, 12200, Berlin, Germany.
Arafat A; Department of Endocrinology, Diabetes and Nutrition, Charité-Universitätsmedizin Berlin, Campus Benjamin Franklin, 12200, Berlin, Germany.
Pivovarova O; Department of Clinical Nutrition, German Institute of Human Nutrition Potsdam-Rehbrücke (DIfE), 14558, Nuthetal, Germany.; German Center for Diabetes Research (DZD), 85764, München-Neuherberg, Germany.; Department of Endocrinology, Diabetes and Nutrition, Charité-Universitätsmedizin Berlin, Campus Benjamin Franklin, 12200, Berlin, Germany.
Machann J; German Center for Diabetes Research (DZD), 85764, München-Neuherberg, Germany.; Institute of Diabetes Research and Metabolic Diseases (IDM) of the Helmholtz Center Munich at the University of Tübingen, Tübingen, Germany.; Section of Experimental Radiology, University Hospital Tübingen, Tübingen, Germany.
Hierholzer J; Diagnostic and Interventional Radiology, Klinikum Ernst von Bergmann, Academic Teaching Hospital, Charité-Universitätsmedizin Berlin, Potsdam, Germany.
Hornemann S; Department of Clinical Nutrition, German Institute of Human Nutrition Potsdam-Rehbrücke (DIfE), 14558, Nuthetal, Germany.
Rohn S; Institute of Food Chemistry, Hamburg School of Food Science, University of Hamburg, Hamburg, Germany.
Pfeiffer AFH; Department Endocrinology and Metabolism, Charité Universitätsmedizin Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, 12203, Berlin, Germany. .
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Źródło :
European journal of nutrition [Eur J Nutr] 2021 Sep; Vol. 60 (6), pp. 3499-3504. Date of Electronic Publication: 2021 Mar 08.
Typ publikacji :
Journal Article
MeSH Terms :
Diabetes Mellitus, Type 2*
Insulin-Like Growth Factor I*/metabolism
Animals ; Diet ; Humans ; Insulin-Like Growth Factor Binding Protein 3 ; Insulin-Like Growth Factor Binding Proteins ; Plant Proteins
Czasopismo naukowe
Tytuł :
Dietary Selenium Deficiency Partially Mimics the Metabolic Effects of Arsenic.
Autorzy :
Carmean CM; Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Illinois at Chicago, Chicago, IL 60612, USA.; Chicago Center for Health and Environment (CACHET), Chicago, IL 60612, USA.
Mimoto M; Section of Endocrinology, Diabetes and Metabolism, University of Chicago, Chicago, IL 60637, USA.
Landeche M; Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Illinois at Chicago, Chicago, IL 60612, USA.
Ruiz D; Committee on Molecular Metabolism and Nutrition, University of Chicago, Chicago, IL 60637, USA.
Chellan B; Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Illinois at Chicago, Chicago, IL 60612, USA.
Zhao L; Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Illinois at Chicago, Chicago, IL 60612, USA.
Schulz MC; Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Illinois at Chicago, Chicago, IL 60612, USA.; Division of Epidemiology and Biostatistics, School of Public Health, Medical Scientist Training Program, University of Illinois at Chicago, Chicago, IL 60612, USA.
Dumitrescu AM; Section of Endocrinology, Diabetes and Metabolism, University of Chicago, Chicago, IL 60637, USA.
Sargis RM; Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Illinois at Chicago, Chicago, IL 60612, USA.; Chicago Center for Health and Environment (CACHET), Chicago, IL 60612, USA.
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Źródło :
Nutrients [Nutrients] 2021 Aug 23; Vol. 13 (8). Date of Electronic Publication: 2021 Aug 23.
Typ publikacji :
Journal Article
MeSH Terms :
Insulin Resistance*
Arsenites/*toxicity
Blood Glucose/*drug effects
Deficiency Diseases/*metabolism
Insulin/*blood
Insulin-Secreting Cells/*drug effects
Selenium/*deficiency
Sodium Compounds/*toxicity
Animals ; Biomarkers/blood ; Blood Glucose/metabolism ; Deficiency Diseases/blood ; Deficiency Diseases/etiology ; Diet ; Disease Models, Animal ; Insulin-Secreting Cells/metabolism ; Male ; Mice, Inbred C57BL
Czasopismo naukowe
Tytuł :
Slightly Elevated Serum Ionic Fluoride Levels Inhibit Insulin Secretion and Increase Glucose Levels in a General Japanese Population: a Cross-sectional Study.
Autorzy :
Itai K; The Research Institute of Strategy for Prevention, Shinkawa 1-39 4F, Chuo-ku, Tokyo, 104-0033, Japan. .
Onoda T; Iwate University Health Care Center, Morioka, Japan.
Nohara M; Department of Health and Welfare, Iwate Prefectural Government, Morioka, Japan.
Kuribayashi T; Faculty of Education, Iwate University, Morioka, Japan.
Tanno K; Department of Hygiene and Preventive Medicine, Iwate Medical University, Morioka, Japan.
Ohsawa M; Morioka Tsunagi Onsen Hospital, Department of Internal Medicine, Morioka, Japan.
Mori M; Department of Nutritional Sciences, Morioka University, Takizawa, Japan.
Okayama A; The Research Institute of Strategy for Prevention, Shinkawa 1-39 4F, Chuo-ku, Tokyo, 104-0033, Japan.
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Źródło :
Biological trace element research [Biol Trace Elem Res] 2021 Aug; Vol. 199 (8), pp. 2819-2825. Date of Electronic Publication: 2020 Oct 08.
Typ publikacji :
Journal Article
MeSH Terms :
Fluorides*
Insulin Resistance*
Adult ; Aged ; Blood Glucose ; Cross-Sectional Studies ; Female ; Glucose ; Humans ; Insulin/metabolism ; Insulin Secretion ; Japan ; Male ; Middle Aged
Czasopismo naukowe
Tytuł :
Beta-cell failure rather than insulin resistance is the major cause of abnormal glucose tolerance in Africans: insight from the Africans in America study.
Autorzy :
Ishimwe MCS; NIDDK, National Institutes of Health, Bethesda, Maryland, USA.
Wentzel A; NIDDK, National Institutes of Health, Bethesda, Maryland, USA.
Shoup EM; NIDDK, National Institutes of Health, Bethesda, Maryland, USA.
Osei-Tutu NH; NIDDK, National Institutes of Health, Bethesda, Maryland, USA.
Hormenu T; NIDDK, National Institutes of Health, Bethesda, Maryland, USA.
Patterson AC; NIDDK, National Institutes of Health, Bethesda, Maryland, USA.
Bagheri H; Clinical Center, National Institutes of Health, Bethesda, Maryland, USA.
DuBose CW; NIDDK, National Institutes of Health, Bethesda, Maryland, USA.
Mabundo LS; NIDDK, National Institutes of Health, Bethesda, Maryland, USA.
Ha J; NIDDK, National Institutes of Health, Bethesda, Maryland, USA.
Sherman A; NIDDK, National Institutes of Health, Bethesda, Maryland, USA.
Sumner AE; NIDDK, National Institutes of Health, Bethesda, Maryland, USA .
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Źródło :
BMJ open diabetes research & care [BMJ Open Diabetes Res Care] 2021 Sep; Vol. 9 (1).
Typ publikacji :
Journal Article; Observational Study; Research Support, N.I.H., Intramural
MeSH Terms :
Glucose Intolerance*/epidemiology
Insulin Resistance*
Insulin-Secreting Cells*
Adult ; Blood Glucose ; Female ; Humans ; Insulin ; Male ; Middle Aged
Czasopismo naukowe
Tytuł :
Clinical research of insulin glargine U300 basal-bolus therapy and insulin degludec/aspart co-formulation in type 2 diabetes mellitus: A real world experience.
Autorzy :
Kisioglu SV; Department of Endocrinology, Health Sciences University Kanuni Training and Research Hospital, Trabzon, Turkey.
Demir AS; Department of Endocrinology, Karadeniz Technical University, Trabzon, Turkey.
Tufekci D; Department of Endocrinology, Karadeniz Technical University, Trabzon, Turkey.
Emur Gunay Y; Department of Endocrinology, Karadeniz Technical University, Trabzon, Turkey.
Coskun H; Department of Endocrinology, Karadeniz Technical University, Trabzon, Turkey.
Ucuncu O; Department of Endocrinology, Karadeniz Technical University, Trabzon, Turkey.
Nuhoglu I; Department of Endocrinology, Karadeniz Technical University, Trabzon, Turkey.
Kocak M; Department of Endocrinology, Karadeniz Technical University, Trabzon, Turkey.
Karakullukcu S; Departmant of Public Health, Bayburt Community Health Center, Bayburt, Turkey.
Ersoz HO; Department of Endocrinology, Medical Park Hospitals Group, Trabzon, Turkey.
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Źródło :
International journal of clinical practice [Int J Clin Pract] 2021 Sep; Vol. 75 (9), pp. e14377. Date of Electronic Publication: 2021 May 29.
Typ publikacji :
Journal Article
MeSH Terms :
Diabetes Mellitus, Type 2*/drug therapy
Insulin Aspart*
Blood Glucose ; Glycated Hemoglobin A/analysis ; Humans ; Hypoglycemic Agents ; Insulin Glargine ; Insulin, Long-Acting ; Retrospective Studies
Czasopismo naukowe
Tytuł :
The effect of curcumin and zinc co-supplementation on glycemic parameters in overweight or obese prediabetic subjects: A phase 2 randomized, placebo-controlled trial with a multi-arm, parallel-group design.
Autorzy :
Karandish M; Nutrition and Metabolic Diseases Research Center, Clinical Sciences Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Mozaffari-Khosravi H; Department of Nutrition, School of Public Health, Shahid Sadoughi University of Medical Sciences and Health Services, Yazd, Iran.
Mohammadi SM; Endocrinology & Metabolism, School of Medicine, Shahid Sadoughi University of Medical Sciences and Health Services, Yazd, Iran.
Cheraghian B; Department of Biostatistics and Epidemiology, School of Health Sciences, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Azhdari M; Department of Nutrition, School of Allied Medical Sciences, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.; Student Research Committee, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
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Źródło :
Phytotherapy research : PTR [Phytother Res] 2021 Aug; Vol. 35 (8), pp. 4377-4387. Date of Electronic Publication: 2021 Apr 23.
Typ publikacji :
Clinical Trial, Phase II; Journal Article; Randomized Controlled Trial
MeSH Terms :
Curcumin*/pharmacology
Dietary Supplements*
Insulin Resistance*
Prediabetic State*/drug therapy
Zinc/*pharmacology
Blood Glucose ; Diabetes Mellitus, Type 2/prevention & control ; Diet, Reducing ; Double-Blind Method ; Humans ; Insulin ; Obesity/drug therapy ; Overweight/drug therapy
Czasopismo naukowe
Tytuł :
Adipose tissue cadmium concentrations as a potential risk factor for insulin resistance and future type 2 diabetes mellitus in GraMo adult cohort.
Autorzy :
Salcedo-Bellido I; Universidad de Granada. Departamento de Medicina Preventiva y Salud Pública, Granada, Spain; Consortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), Madrid, Spain; Instituto de Investigación Biosanitaria ibs.Granada, Granada, Spain.
Gómez-Peña C; Unidad de Gestión Clínica de Farmacia Hospitalaria, Hospital Universitario San Cecilio, Granada, Spain.
Pérez-Carrascosa FM; Universidad de Granada. Departamento de Medicina Preventiva y Salud Pública, Granada, Spain; Instituto de Investigación Biosanitaria ibs.Granada, Granada, Spain; Radiation Oncology Department, Virgen de las Nieves University Hospital, Granada, Spain.
Vrhovnik P; Slovenian National Building and Civil Engineering Institute (ZAG), Ljubljana, Slovenia.
Mustieles V; Consortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), Madrid, Spain; Instituto de Investigación Biosanitaria ibs.Granada, Granada, Spain; University of Granada, Center for Biomedical Research (CIBM), Granada, Spain.
Echeverría R; Universidad de Granada. Departamento de Medicina Preventiva y Salud Pública, Granada, Spain.
Fiket Ž; Ruđer Bošković Institute, Division for Marine and Environmental Research, Zagreb, Croatia.
Pérez-Díaz C; Universidad de Granada. Departamento de Medicina Preventiva y Salud Pública, Granada, Spain.
Barrios-Rodríguez R; Universidad de Granada. Departamento de Medicina Preventiva y Salud Pública, Granada, Spain; Consortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), Madrid, Spain; Instituto de Investigación Biosanitaria ibs.Granada, Granada, Spain. Electronic address: .
Jiménez-Moleón JJ; Universidad de Granada. Departamento de Medicina Preventiva y Salud Pública, Granada, Spain; Consortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), Madrid, Spain; Instituto de Investigación Biosanitaria ibs.Granada, Granada, Spain.
Arrebola JP; Universidad de Granada. Departamento de Medicina Preventiva y Salud Pública, Granada, Spain; Consortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), Madrid, Spain; Instituto de Investigación Biosanitaria ibs.Granada, Granada, Spain. Electronic address: .
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Źródło :
The Science of the total environment [Sci Total Environ] 2021 Aug 01; Vol. 780, pp. 146359. Date of Electronic Publication: 2021 Mar 10.
Typ publikacji :
Journal Article
MeSH Terms :
Diabetes Mellitus, Type 2*/epidemiology
Insulin Resistance*
Adipose Tissue ; Adult ; Blood Glucose ; Cadmium ; Cross-Sectional Studies ; Humans ; Insulin ; Risk Factors ; Spain
Czasopismo naukowe
Tytuł :
Histone modifications influence the insulin-signaling genes and are related to insulin resistance in human adipocytes.
Autorzy :
Małodobra-Mazur M; Department of Forensic Medicine, Department of Molecular Techniques, Wroclaw Medical University, Sklodowskiej-Curie 52, 50-369, Wroclaw, Poland. Electronic address: .
Cierzniak A; Department of Forensic Medicine, Department of Molecular Techniques, Wroclaw Medical University, Sklodowskiej-Curie 52, 50-369, Wroclaw, Poland.
Myszczyszyn A; 1st Department of Gynaecology and Obstetrics, Wroclaw Medical University, ul. T. Chałubińskiego 3, 50-368, Wroclaw, Poland.
Kaliszewski K; Department of General, Minimally Invasive and Endocrine Surgery, Wroclaw Medical University, Borowska 213, 50-556, Wroclaw, Poland.
Dobosz T; Department of Forensic Medicine, Department of Molecular Techniques, Wroclaw Medical University, Sklodowskiej-Curie 52, 50-369, Wroclaw, Poland.
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Źródło :
The international journal of biochemistry & cell biology [Int J Biochem Cell Biol] 2021 Aug; Vol. 137, pp. 106031. Date of Electronic Publication: 2021 Jun 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adipogenesis*
Epigenesis, Genetic*
Insulin Resistance*
Histones/*genetics
Insulin/*metabolism
Intra-Abdominal Fat/*pathology
Subcutaneous Fat/*pathology
3T3-L1 Cells ; Adult ; Animals ; Case-Control Studies ; DNA Methylation ; Humans ; Insulin/genetics ; Intra-Abdominal Fat/metabolism ; Mice ; Middle Aged ; Subcutaneous Fat/metabolism
Czasopismo naukowe
Tytuł :
The Effect of Prestudy Insulin Therapy on Safety and Efficacy of Human Regular U-500 Insulin by Pump or Injection: A Posthoc Analysis.
Autorzy :
Hood RC; Endocrine Clinic of Southeast Texas, Beaumont, Texas. Electronic address: .
Chen Y; Techdata Service Company, LLC, King of Prussia, Pennsylvania.
Sindelar DK; Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana.
Ly T; Insulet Corporation, Acton, Massachusetts.
Juneja R; Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana.
Pollom RD; Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana.
Ilag L; Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana.
Wysham C; Rockwood Clinic, Spokane, Washington.
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Źródło :
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists [Endocr Pract] 2021 Aug; Vol. 27 (8), pp. 783-789. Date of Electronic Publication: 2021 Jan 28.
Typ publikacji :
Journal Article; Randomized Controlled Trial
MeSH Terms :
Diabetes Mellitus, Type 2*/drug therapy
Insulin*/adverse effects
Blood Glucose ; Glycated Hemoglobin A/analysis ; Humans ; Hypoglycemic Agents/adverse effects ; Injections, Subcutaneous ; Insulin Infusion Systems
Czasopismo naukowe
Tytuł :
COVID-19 May Increase the Risk of Insulin Resistance in Adult Patients Without Diabetes: A 6-Month Prospective Study.
Autorzy :
Chen M; Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Zhu B; Department of Endocrinology and Metabolism, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China.
Chen D; Department of Infectious Disease, The Ding Li Clinical College of Wenzhou Medical University and Sixth People's Hospital of Wenzhou, Wenzhou, Zhejiang, China.
Hu X; Department of Infectious Disease, The Ding Li Clinical College of Wenzhou Medical University and Sixth People's Hospital of Wenzhou, Wenzhou, Zhejiang, China.
Xu X; Department of Infectious Disease, The Ding Li Clinical College of Wenzhou Medical University and Sixth People's Hospital of Wenzhou, Wenzhou, Zhejiang, China.
Shen WJ; Division of Endocrinology, Gerontology and Metabolism, Stanford University School of Medicine, Stanford, California; Geriatric Research, Education, and Clinical Center, VA Palo Alto Health Care System, Palo Alto, California.
Hu C; Department of Infectious Disease, The Ding Li Clinical College of Wenzhou Medical University and Sixth People's Hospital of Wenzhou, Wenzhou, Zhejiang, China. Electronic address: .
Li J; Shanghai Pudong New Area Mental Health Center, Tongji University School of Medicine, Shanghai, China. Electronic address: .
Qu S; Department of Endocrinology and Metabolism, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China. Electronic address: .
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Źródło :
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists [Endocr Pract] 2021 Aug; Vol. 27 (8), pp. 834-841. Date of Electronic Publication: 2021 Apr 19.
Typ publikacji :
Journal Article
MeSH Terms :
COVID-19*
Diabetes Mellitus*
Insulin Resistance*
Adult ; Blood Glucose ; Humans ; Insulin ; Male ; Prospective Studies ; SARS-CoV-2 ; Triglycerides
Czasopismo naukowe
Tytuł :
MiR-205 is up-regulated in islets of diabetes-susceptible mice and targets the diabetes gene Tcf7l2.
Autorzy :
Ouni M; Department of Experimental Diabetology, German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), Nuthetal, Germany.; German Center for Diabetes Research (DZD), München-Neuherberg, Germany.
Gottmann P; Department of Experimental Diabetology, German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), Nuthetal, Germany.; German Center for Diabetes Research (DZD), München-Neuherberg, Germany.
Westholm E; Department of Experimental Diabetology, German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), Nuthetal, Germany.; Unit of Islet Cell Exocytosis, Department of Clinical Sciences Malmö, Lund University Diabetes Centre, Lund University, Malmö, Sweden.
Schwerbel K; Department of Experimental Diabetology, German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), Nuthetal, Germany.; German Center for Diabetes Research (DZD), München-Neuherberg, Germany.
Jähnert M; Department of Experimental Diabetology, German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), Nuthetal, Germany.; German Center for Diabetes Research (DZD), München-Neuherberg, Germany.
Stadion M; Department of Experimental Diabetology, German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), Nuthetal, Germany.; German Center for Diabetes Research (DZD), München-Neuherberg, Germany.
Rittig K; Clinic for Angiology and Diabetology, Frankfurt (Oder), Germany.; Institute of Nutritional Science, University of Potsdam, Brandenburg, Germany.
Vogel H; Department of Experimental Diabetology, German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), Nuthetal, Germany.; German Center for Diabetes Research (DZD), München-Neuherberg, Germany.; Research Group Genetics of Obesity, German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), Nuthetal, Germany.; Research Group Molecular and Clinical Life Science of Metabolic Diseases, Faculty of Health Sciences Brandenburg, University of Potsdam, Brandenburg, Germany.
Schürmann A; Department of Experimental Diabetology, German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), Nuthetal, Germany.; German Center for Diabetes Research (DZD), München-Neuherberg, Germany.; Institute of Nutritional Science, University of Potsdam, Brandenburg, Germany.
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Źródło :
Acta physiologica (Oxford, England) [Acta Physiol (Oxf)] 2021 Aug; Vol. 232 (4), pp. e13693. Date of Electronic Publication: 2021 Jun 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Diabetes Mellitus, Experimental*/genetics
Diabetes Mellitus, Experimental*/metabolism
Diabetes Mellitus, Type 2*/genetics
Diabetes Mellitus, Type 2*/metabolism
Insulin-Secreting Cells*/metabolism
Islets of Langerhans*/metabolism
MicroRNAs/*metabolism
Animals ; Insulin/metabolism ; Insulin Secretion ; Mice ; MicroRNAs/genetics ; Transcription Factor 7-Like 2 Protein/genetics ; Transcription Factor 7-Like 2 Protein/metabolism ; Transcriptome
Czasopismo naukowe
Tytuł :
Insulin therapy development beyond 100 years.
Autorzy :
Home PD; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK. Electronic address: .
Mehta R; Metabolic Diseases Research Unit, National Institute of Medical Sciences and Nutrition Salvador Zubiran, Mexico City, Mexico.
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Źródło :
The lancet. Diabetes & endocrinology [Lancet Diabetes Endocrinol] 2021 Oct; Vol. 9 (10), pp. 695-707. Date of Electronic Publication: 2021 Sep 01.
Typ publikacji :
Historical Article; Journal Article; Review
MeSH Terms :
Drug Development*/history
Drug Development*/trends
Insulin*/administration & dosage
Insulin*/history
Diabetes Mellitus/drug therapy ; Diabetes Mellitus/epidemiology ; Diabetes Mellitus/history ; Drug Administration Routes ; Drug Compounding/history ; Drug Compounding/trends ; History, 20th Century ; History, 21st Century ; Humans ; Insulin Infusion Systems/history
Czasopismo naukowe
Tytuł :
Ultrasound markers for prediction of gestational diabetes mellitus in early pregnancy in Egyptian women: observational study.
Autorzy :
Saif Elnasr I; Obstetrics and Gynecology Department, Faculty of Medicine, Menoufia University, Shibin el Kom, Egypt.
Ammar H; Obstetrics and Gynecology Department, Faculty of Medicine, Menoufia University, Shibin el Kom, Egypt.
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Źródło :
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians [J Matern Fetal Neonatal Med] 2021 Oct; Vol. 34 (19), pp. 3120-3126. Date of Electronic Publication: 2020 Mar 06.
Typ publikacji :
Journal Article; Observational Study
MeSH Terms :
Diabetes, Gestational*/diagnostic imaging
Insulin Resistance*
Blood Glucose ; Body Mass Index ; Egypt/epidemiology ; Female ; Humans ; Insulin ; Intra-Abdominal Fat/diagnostic imaging ; Pregnancy ; Prospective Studies
Czasopismo naukowe
Tytuł :
[Study on effect of gypenosides on insulin sensitivity of rats with diabetes mellitus via regulating NF-κB signaling pathway].
Autorzy :
Zhu KN; Huzhou Institute for Food and Drug Control Huzhou 313000, China.
Tian SS; College of Pharmaceutical Science, Zhejiang Chinese Medical University Hangzhou 311402, China.
Wang H; College of Pharmaceutical Science, Zhejiang Chinese Medical University Hangzhou 311402, China.
Tian YS; Jiangsu Key Laboratory of Traditional Chinese Medicine Evaluation and Translational Research, China Pharmaceutical University Nanjing 211198, China.
Gu GZ; Huzhou Institute for Food and Drug Control Huzhou 313000, China.
Qiu YY; Huzhou Institute for Food and Drug Control Huzhou 313000, China.
Zhang L; Huzhou Institute for Food and Drug Control Huzhou 313000, China.
Yang HX; Huzhou Institute for Food and Drug Control Huzhou 313000, China.
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Źródło :
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica [Zhongguo Zhong Yao Za Zhi] 2021 Sep; Vol. 46 (17), pp. 4488-4496.
Typ publikacji :
Journal Article
MeSH Terms :
Diabetes Mellitus, Experimental*/drug therapy
Diabetes Mellitus, Type 2*/drug therapy
Diabetes Mellitus, Type 2*/genetics
Insulin Resistance*
Animals ; Gynostemma ; Insulin ; NF-kappa B/genetics ; NF-kappa B/metabolism ; Plant Extracts ; Rats ; Signal Transduction
Czasopismo naukowe
Tytuł :
The effect of grapes/grape products on glycemic response: A systematic review and meta-analysis of randomized controlled trials.
Autorzy :
Moodi V; School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Abedi S; Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
Esmaeilpour M; Department of Nutrition, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran.
Asbaghi O; Student Research Committee, Lorestan University of Medical Sciences, Khorramabad, Iran.
Izadi F; Department of Clinical Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran.
Shirinbakhshmasoleh M; Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
Behrouzian M; Department of Pediatrics, Faculty of Medicine, Golestan teaching hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Shahriari A; Roozbeh Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Ghaedi E; Department of Cellular and Molecular Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran.
Miraghajani M; Cancer Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.; The Early Life Research Unit, Academic Division of Child Health, Obstetrics and Gynaecology, and Nottingham Digestive Disease Centre and Biomedical Research Centre, The School of Medicine, University of Nottingham, Nottingham, UK.
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Źródło :
Phytotherapy research : PTR [Phytother Res] 2021 Sep; Vol. 35 (9), pp. 5053-5067. Date of Electronic Publication: 2021 Apr 24.
Typ publikacji :
Journal Article; Meta-Analysis; Review; Systematic Review
MeSH Terms :
Diabetes Mellitus, Type 2*/drug therapy
Insulin Resistance*
Vitis*/chemistry
Plant Preparations/*therapeutic use
Adult ; Blood Glucose ; Dietary Supplements ; Humans ; Insulin ; Randomized Controlled Trials as Topic
Czasopismo naukowe
Tytuł :
Current utilization patterns for long-acting insulin analogues including biosimilars among selected Asian countries and the implications for the future.
Autorzy :
Godman B; Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, United Kingdom.; Division of Public Health Pharmacy and Management, School of Pharmacy, Sefako Makgatho Health Sciences University, Pretoria, South Africa.; School of Pharmaceutical Sciences, Universiti Sains Malaysia, Penang, Malaysia.
Haque M; Faculty of Medicine and Defence Health, Unit of Pharmacology, Universiti Pertahanan Nasional Malaysia (National Defence University of Malaysia), Kuala Lumpur, Malaysia.
Kumar S; Department of Periodontology and Implantology, Karnavati University, Gandhinagar, India.
Islam S; Department of Microbiology, Jahangirnagar University, Dhaka, Bangladesh.
Charan J; Department of Pharmacology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.
Akter F; Department of Endocrinology, Chittagong Medical College, Chittagong, Bangladesh.
Kurdi A; Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, United Kingdom.; Division of Public Health Pharmacy and Management, School of Pharmacy, Sefako Makgatho Health Sciences University, Pretoria, South Africa.; Department of Pharmacology, College of Pharmacy, Hawler Medical University, Erbil, Iraq.
Allocati E; Istituto di Ricerche Farmacologiche 'Mario Negri' IRCCS, Milan, Italy.
Bakar MA; Department of Endocrinology and Metabolism, Chattogram Maa-O-Shishu Hospital Medical College, Agrabad, Chattogram, Bangladesh.
Rahim SA; BIRDEM General Hospital, Shahbag Square, Dhaka, Bangladesh.
Sultana N; Department of Endocrinology and Metabolism, Bangabandhu Sheik Mujib Medical University Hospital, Dhaka, Bangladesh.
Deeba F; Department of Obstetrics and Gynaecology, Bangabandhu Sheik Mujib Medical University, Dhaka, Bangladesh.
Halim Khan MA; Shaheed Suhrawardy Medical College Hospital, Dhaka, Bangladesh.
Alam ABMM; Shaheed Suhrawardy Medical College Hospital, Dhaka, Bangladesh.
Jahan I; Department of Physiology, Eastern Medical College, Cumilla, Bangladesh.
Kamal ZM; National Institute of Mental Health (NIMH), Dhaka, Bangladesh.
Hasin H; Epsom and St Helier University Hospitals NHS Trust, Carshalton, Surrey, United Kingdom.
Munzur-E-Murshid; Handicap International, Kurigram, Bangladesh.
Nahar S; Department of Microbiology, Jahangirnagar University, Dhaka, Bangladesh.
Haque M; Human Resource Department, Square Toiletries Limited, Dhaka, Bangladesh.
Dutta S; Department of Pharmacology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.
Abhayanand JP; Department of Pharmacology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.
Kaur RJ; Department of Pharmacology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.
Acharya J; Department of Dentistry, SP Medical College, Bikaner, Rajasthan, India.
Sugahara T; Faculty of Economics, Hosei University, Tokyo, Japan.
Kwon HY; Division of Biology and Public Health, Mokwon University, Daejeon, South Korea.
Bae S; College of Pharmacy, Ewha Womans University, Seoul, South Korea.
Khuan KKP; Friends' Pharmacy, Wisma Kobesi, Malaysia.
Khan TA; National Institute of Health, Islamabad, Pakistan.
Hussain S; National Institute of Health, Islamabad, Pakistan.
Saleem Z; Department of Pharmacy Practice, Faculty of Pharmacy, The University of Lahore, Lahore, Pakistan.
Pisana A; Department of Global Public Health, Karolinska Institutet, Stockholm, Sweden.
Wale J; Independent Consumer Advocate, Brunswick, Victoria, Australia.
Jakovljevic M; Faculty of Economics, Hosei University, Tokyo, Japan.; Department of Global Health Economics and Policy, University of Kragujevac, Kragujevac, Serbia.
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Źródło :
Current medical research and opinion [Curr Med Res Opin] 2021 Sep; Vol. 37 (9), pp. 1529-1545. Date of Electronic Publication: 2021 Jul 14.
Typ publikacji :
Journal Article
MeSH Terms :
Biosimilar Pharmaceuticals*/therapeutic use
Diabetes Mellitus, Type 2*/drug therapy
Hypoglycemic Agents*/therapeutic use
Insulin, Long-Acting*/therapeutic use
Asia ; Humans ; Insulin ; Japan ; Pakistan
Czasopismo naukowe

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