Temat: "Insulin" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Investigating the Effects of Diet-Induced Prediabetes on Skeletal Muscle Strength in Male Sprague Dawley Rats.
Autorzy:: Dlamini M; Department of Human Physiology, School of Laboratory Medicine, Medical Sciences, College of Health Sciences, University of KwaZulu-Natal, Durban X54001, South Africa.
Khathi A; Department of Human Physiology, School of Laboratory Medicine, Medical Sciences, College of Health Sciences, University of KwaZulu-Natal, Durban X54001, South Africa.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Apr 06; Vol. 25 (7). Date of Electronic Publication: 2024 Apr 06.
Typ publikacji:: Journal Article
MeSH Terms:: Prediabetic State*/etiology
Insulin Resistance*
Diabetes Mellitus, Type 2*/etiology
Hyperglycemia*
Male ; Rats ; Animals ; Rats, Sprague-Dawley ; Blood Glucose ; Glycated Hemoglobin ; Diet/adverse effects ; Muscle, Skeletal ; Insulin ; Insulin, Regular, Human

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Skocz do pozycji: 2.

Tytuł:: Exploring the Pathophysiology of ATP-Dependent Potassium Channels in Insulin Resistance.
Autorzy:: Rodríguez-Rivera NS; Laboratorio de Farmacología y Bioquímica Clínica, Departamento de Farmacología, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico.
Barrera-Oviedo D; Laboratorio de Farmacología y Bioquímica Clínica, Departamento de Farmacología, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Apr 06; Vol. 25 (7). Date of Electronic Publication: 2024 Apr 06.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Insulin Resistance*
Diabetes Mellitus, Type 2*
Humans ; Potassium Channels ; Insulin ; Insulin, Regular, Human ; Pancreatic Hormones ; KATP Channels ; Obesity ; Potassium ; Adenosine Triphosphate

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Skocz do pozycji: 3.

Tytuł:: A Novel Mutation in the INSR Gene Causes Severe Insulin Resistance and Rabson-Mendenhall Syndrome in a Paraguayan Patient.
Autorzy:: Rojas Velazquez MN; Department of Pediatrics, University Children's Hospital Bern, Inselspital, 3010 Bern, Switzerland.; Translational Hormone Research Program, Department of Biomedical Research, University of Bern, 3010 Bern, Switzerland.; Graduate School for Cellular and Biomedical Sciences, University of Bern, 3010 Bern, Switzerland.
Blanco F; Facultad de Ciencias Médicas, Universidad Nacional de Asunción, Asunción 111241, Paraguay.; Instituto de Previsión Social, Asunción 172755, Paraguay.
Ayala-Lugo A; Laboratorio de Genética Molecular, Departamento de Genética, Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción 111241, Paraguay.
Franco L; Laboratorio de Genética Molecular, Departamento de Genética, Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción 111241, Paraguay.
Jolly V; Laboratorio de Genética Molecular, Departamento de Genética, Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción 111241, Paraguay.
Di Tore D; Laboratorio de Genética Molecular, Departamento de Genética, Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción 111241, Paraguay.
Martínez de Lapiscina I; Department of Pediatrics, University Children's Hospital Bern, Inselspital, 3010 Bern, Switzerland.; Translational Hormone Research Program, Department of Biomedical Research, University of Bern, 3010 Bern, Switzerland.
Janner M; Department of Pediatrics, University Children's Hospital Bern, Inselspital, 3010 Bern, Switzerland.
Flück CE; Department of Pediatrics, University Children's Hospital Bern, Inselspital, 3010 Bern, Switzerland.; Translational Hormone Research Program, Department of Biomedical Research, University of Bern, 3010 Bern, Switzerland.
Pandey AV; Department of Pediatrics, University Children's Hospital Bern, Inselspital, 3010 Bern, Switzerland.; Translational Hormone Research Program, Department of Biomedical Research, University of Bern, 3010 Bern, Switzerland.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Mar 08; Vol. 25 (6). Date of Electronic Publication: 2024 Mar 08.
Typ publikacji:: Case Reports; Journal Article
MeSH Terms:: Donohue Syndrome*/diagnosis
Insulin Resistance*/genetics
Child ; Female ; Humans ; Receptor, Insulin/genetics ; Receptor, Insulin/metabolism ; Mutation ; Valine/genetics ; Antigens, CD/genetics

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Skocz do pozycji: 4.

Tytuł:: Resolution of insulin resistance, lactic acidosis, and decrease in mechanical support requirements in patients post orthotopic heart transplant with the use of long-acting insulin glargine.
Autorzy:: Darwish R; Anesthesiology Institute, Surgical Critical Care Division, Cleveland Clinic Florida, Weston, USA. .
Chen E; Anesthesiology Institute, Surgical Critical Care Division, Cleveland Clinic Florida, Weston, USA.
Minear S; Anesthesiology Institute, Surgical Critical Care Division, Cleveland Clinic Florida, Weston, USA.
Sheffield C; Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic Florida, Weston, USA.; Pokaż więcej
Źródło:: Journal of cardiothoracic surgery [J Cardiothorac Surg] 2024 Feb 16; Vol. 19 (1), pp. 99. Date of Electronic Publication: 2024 Feb 16.
Typ publikacji:: Journal Article
MeSH Terms:: Acidosis, Lactic*/therapy
Insulin Resistance*
Heart Transplantation*
Humans ; Insulin Glargine ; Insulin, Long-Acting ; Retrospective Studies ; Insulin/therapeutic use ; Lactic Acid

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Skocz do pozycji: 5.

Tytuł:: Association of cigarette smoking with cerebrospinal fluid biomarkers of insulin sensitivity and neurodegeneration.
Autorzy:: Wang F; Beijing Huilongguan Hospital, Peking University, Beijing, China.
Li H; Department of Biomedical Engineering, College of Future Technology, Peking University, Beijing, China.
Kong T; Xinjiang Key Laboratory of Neurological Disorder Research, the Second Affiliated Hospital of Xinjiang Medical University, Urumqi, China.
Shan L; Department of Anesthesiology, the Second Affiliated Hospital of Xiamen Medical College, Xiamen, China.
Guo J; Medical Section, The Third Hospital of BaoGang Group, Baotou, China.; The Affiliated Hospital of Inner Mongolia Medical University, Huhhot, China.
Wu Y; Beijing Huilongguan Hospital, Peking University, Beijing, China.
Luo X; Department of Psychiatry, Yale University School of Medicine, New Haven, USA.
Satyanarayanan SK; Department of Psychiatry & Mind-Body Interface Laboratory (MBI-Lab), China Medical University Hospital, Taichung, Taiwan.; College of Medicine, China Medical University, Taichung, Taiwan.
Su KP; Department of Psychiatry & Mind-Body Interface Laboratory (MBI-Lab), China Medical University Hospital, Taichung, Taiwan.; College of Medicine, China Medical University, Taichung, Taiwan.; An-Nan Hospital, China Medical University, Tainan, Taiwan.
Liu Y; Zhejiang Provincial Clinical Research Center for Mental Disorders, The Affiliated Wenzhou Kangning Hospital, Wenzhou Medical University, Wenzhou, China.; Pokaż więcej
Źródło:: Brain and behavior [Brain Behav] 2024 Feb; Vol. 14 (2), pp. e3432.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Alzheimer Disease*/cerebrospinal fluid
Alzheimer Disease*/epidemiology
Cigarette Smoking*/cerebrospinal fluid
Insulin Resistance*
Humans ; Biomarkers/cerebrospinal fluid ; Cross-Sectional Studies ; Glucose/cerebrospinal fluid ; Insulin/cerebrospinal fluid ; Lactates/cerebrospinal fluid ; Insulin-Like Growth Factor I/cerebrospinal fluid

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Skocz do pozycji: 6.

Tytuł:: Insulin-like growth factor-1 (IGF-1) levels in multiple sclerosis patients: A systematic review and meta-analysis.
Autorzy:: Yaghoobpoor S; Student Research Committee, Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Fathi M; Student Research Committee, Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Vakili K; Student Research Committee, Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Sayehmiri F; Skull Base Research Center, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Alipour M; Medical Student, Department of Medicine, Islamic Azad University Tehran Medical Sciences, Tehran, Iran.
Miriran ZS; Isfahan University of Medical Sciences, Isfahan, Iran.
Ghayyem H; School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Tutunchian Z; Advanced Diagnostic and Interventional Radiology Research Center(ADIR), Tehran University of Medical Science, Tehran, Iran.
Hajibeygi R; Advanced Diagnostic and Interventional Radiology Research Center(ADIR), Tehran University of Medical Science, Tehran, Iran.; Department of Molecular Biology, Pasteur Institute of Iran, Tehran, Iran.
Batool Z; Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan.
Mirzadeh M; Department of Surgery, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Aghazadeh MH; Department of Surgery, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Hajiesmaeili M; Anesthesia and Critical Care Department, Critical Care Quality Improvement Research Center, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2024 Apr 17; Vol. 19 (4), pp. e0297091. Date of Electronic Publication: 2024 Apr 17 (Print Publication: 2024).
Typ publikacji:: Meta-Analysis; Systematic Review; Journal Article
MeSH Terms:: Insulin-Like Growth Factor I*/metabolism
Multiple Sclerosis*
Humans ; Insulin-Like Growth Factor Binding Protein 3 ; Insulin-Like Growth Factor Binding Protein 1 ; Insulin-Like Growth Factor Binding Protein 2 ; Insulin-Like Peptides ; Insulin-Like Growth Factor Binding Proteins

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Skocz do pozycji: 7.

Tytuł:: The importance of intravenous glucose tolerance test glucose stimulus for the evaluation of insulin secretion.
Autorzy:: Godsland IF; Division of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, UK. .; Wynn Reader in Human Metabolism, Section of Metabolic Medicine, Faculty of Medicine, Imperial College London (St Mary's Campus), Room G1, Norfolk Place, London, W2 2NH, UK. .
Johnston DG; Division of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, UK.; Department of Diabetes and Endocrinology, St Marys Hospital, Imperial College Healthcare NHS Trust, London, UK.
Alberti K; Division of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, UK.
Oliver N; Division of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, UK.; Department of Diabetes and Endocrinology, St Marys Hospital, Imperial College Healthcare NHS Trust, London, UK.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Mar 28; Vol. 14 (1), pp. 7451. Date of Electronic Publication: 2024 Mar 28.
Typ publikacji:: Journal Article
MeSH Terms:: Blood Glucose*/metabolism
Insulin Resistance*
Humans ; Glucose Tolerance Test ; Insulin Secretion ; Insulin/metabolism ; Glucose ; Obesity

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Skocz do pozycji: 8.

Tytuł:: Insulin Secretion Defect in Children and Adolescents with Obesity: Clinical and Molecular Genetic Characterization.
Autorzy:: Enders-Seidlitz H; Charité Universitätsmedizin Berlin, Berlin, Germany.
Raile K; Vivantes Klinikum, Berlin, Germany.
Gong M; Max Delbrück Center for Molecular Medicine, Berlin, Germany.
Galler A; Charité Universitätsmedizin Berlin, Berlin, Germany.
Kuehnen P; Charité Universitätsmedizin Berlin, Berlin, Germany.
Wiegand S; Charité Universitätsmedizin Berlin, Berlin, Germany.; Pokaż więcej
Źródło:: Journal of diabetes research [J Diabetes Res] 2024 Mar 20; Vol. 2024, pp. 5558634. Date of Electronic Publication: 2024 Mar 20 (Print Publication: 2024).
Typ publikacji:: Journal Article
MeSH Terms:: Pediatric Obesity*/genetics
Insulin Resistance*/genetics
Diabetes Mellitus, Type 2*/metabolism
Humans ; Child ; Adolescent ; Insulin Secretion ; Insulin/metabolism ; Glucose ; Molecular Biology ; Blood Glucose/metabolism

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Skocz do pozycji: 9.

Tytuł:: Imeglimin mitigates the accumulation of dysfunctional mitochondria to restore insulin secretion and suppress apoptosis of pancreatic β-cells from db/db mice.
Autorzy:: Aoyagi K; Department of Cellular Biochemistry, Kyorin University School of Medicine, Mitaka, Tokyo, 181-8611, Japan.
Nishiwaki C; Department of Cellular Biochemistry, Kyorin University School of Medicine, Mitaka, Tokyo, 181-8611, Japan.
Nakamichi Y; Department of Cellular Biochemistry, Kyorin University School of Medicine, Mitaka, Tokyo, 181-8611, Japan.
Yamashita SI; Department of Cellular Physiology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, 951-8510, Japan.
Kanki T; Department of Cellular Physiology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, 951-8510, Japan.
Ohara-Imaizumi M; Department of Cellular Biochemistry, Kyorin University School of Medicine, Mitaka, Tokyo, 181-8611, Japan. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Mar 14; Vol. 14 (1), pp. 6178. Date of Electronic Publication: 2024 Mar 14.
Typ publikacji:: Journal Article
MeSH Terms:: Diabetes Mellitus, Type 2*/drug therapy
Diabetes Mellitus, Type 2*/metabolism
Diabetes Mellitus, Experimental*/drug therapy
Diabetes Mellitus, Experimental*/metabolism
Insulin-Secreting Cells*/metabolism
Triazines*
Mice ; Animals ; Insulin Secretion ; Reactive Oxygen Species/metabolism ; Mice, Inbred C57BL ; Insulin/metabolism ; Glucose/metabolism ; Mice, Inbred Strains ; Mitochondria/metabolism ; Apoptosis

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Skocz do pozycji: 10.

Tytuł:: Insulin and IGF-1 have both overlapping and distinct effects on CD4 T cell mitochondria, metabolism, and function.
Autorzy:: Kiernan K; Department of Immunology, Duke University School of Medicine, Durham, NC, USA.
Alwarawrah Y; Department of Pediatrics, Division of Pediatric Endocrinology, University of North Carolina School of Medicine, Chapel Hill, NC, USA.
Nichols AG; Department of Pediatrics, Division of Pediatric Endocrinology, University of North Carolina School of Medicine, Chapel Hill, NC, USA.
Danzaki K; Department of Immunology, Duke University School of Medicine, Durham, NC, USA.
MacIver NJ; Department of Pediatrics, Division of Pediatric Endocrinology, University of North Carolina School of Medicine, Chapel Hill, NC, USA. nancie_.; Department of Nutrition, School of Medicine and Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA. nancie_.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Feb 21; Vol. 14 (1), pp. 4331. Date of Electronic Publication: 2024 Feb 21.
Typ publikacji:: Journal Article
MeSH Terms:: Insulin-Like Growth Factor I*/metabolism
Insulin*/metabolism
Receptor, IGF Type 1/metabolism ; Receptor, Insulin/metabolism ; Signal Transduction ; Mitochondria/metabolism ; CD4-Positive T-Lymphocytes/metabolism

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Skocz do pozycji: 11.

Tytuł:: Insulin Resistance: The Increased Risk of Cancers.
Autorzy:: Szablewski L; Chair and Department of General Biology and Parasitology, Medical University of Warsaw, Chałubińskiego 5 Str., 02-004 Warsaw, Poland.; Pokaż więcej
Źródło:: Current oncology (Toronto, Ont.) [Curr Oncol] 2024 Feb 13; Vol. 31 (2), pp. 998-1027. Date of Electronic Publication: 2024 Feb 13.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Insulin Resistance*/physiology
Diabetes Mellitus, Type 2*/complications
Diabetes Mellitus, Type 2*/metabolism
Hyperinsulinism*/complications
Hyperinsulinism*/metabolism
Humans ; Neoplasm Recurrence, Local ; Obesity/complications ; Insulin

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Skocz do pozycji: 12.

Tytuł:: Cyb5r3 activation rescues secondary failure to sulfonylurea but not β-cell dedifferentiation.
Autorzy:: Watanabe H; Department of Medicine, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York, United States of America.; Naomi Berrie Diabetes Center, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York, United States of America.
Asahara SI; Department of Medicine, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York, United States of America.; Naomi Berrie Diabetes Center, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York, United States of America.; Division of Diabetes and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan.
Son J; Department of Medicine, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York, United States of America.; Naomi Berrie Diabetes Center, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York, United States of America.
McKimpson WM; Department of Medicine, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York, United States of America.; Naomi Berrie Diabetes Center, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York, United States of America.
de Cabo R; Translational Gerontology Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America.
Accili D; Department of Medicine, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York, United States of America.; Naomi Berrie Diabetes Center, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2024 Feb 09; Vol. 19 (2), pp. e0297555. Date of Electronic Publication: 2024 Feb 09 (Print Publication: 2024).
Typ publikacji:: Journal Article
MeSH Terms:: Diabetes Mellitus, Type 2*/drug therapy
Insulin Resistance*
Insulin-Secreting Cells*
Cytochrome-B(5) Reductase*/genetics
Cytochrome-B(5) Reductase*/metabolism
Animals ; Mice ; Cell Dedifferentiation ; Insulin/pharmacology ; Sulfonylurea Compounds/pharmacology

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Skocz do pozycji: 13.

Tytuł:: The IGF-PAPP-A-Stanniocalcin Axis in Serum and Ascites Associates with Prognosis in Patients with Ovarian Cancer.
Autorzy:: Hjortebjerg R; Steno Diabetes Center Odense, Odense University Hospital, 5000 Odense, Denmark.; Department of Clinical Research, University of Southern Denmark, 5230 Odense, Denmark.
Høgdall C; Department of Gynecology, Juliane Marie Center, Rigshospitalet, 2100 Copenhagen, Denmark.
Hansen KH; Endocrine Research Unit, Department of Endocrinology, Odense University Hospital, 5000 Odense, Denmark.; OPEN Lab, Odense University Hospital, 5000 Odense, Denmark.
Høgdall E; Department of Pathology, Herlev University Hospital, 2730 Herlev, Denmark.
Frystyk J; Department of Clinical Research, University of Southern Denmark, 5230 Odense, Denmark.; Endocrine Research Unit, Department of Endocrinology, Odense University Hospital, 5000 Odense, Denmark.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Feb 07; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 07.
Typ publikacji:: Journal Article
MeSH Terms:: Insulin-Like Growth Factor I*/metabolism
Ovarian Neoplasms*/complications
Glycoproteins*
Humans ; Female ; Insulin-Like Growth Factor II ; Pregnancy-Associated Plasma Protein-A/metabolism ; Ascites ; Prospective Studies ; Ecosystem ; Longitudinal Studies

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Skocz do pozycji: 14.

Tytuł:: AMPK and Beyond: The Signaling Network Controlling RabGAPs and Contraction-Mediated Glucose Uptake in Skeletal Muscle.
Autorzy:: Peifer-Weiß L; Institute for Clinical Biochemistry and Pathobiochemistry, German Diabetes Center (DDZ), Leibniz Center for Diabetes Research at Heinrich Heine University, Medical Faculty, 40225 Düsseldorf, Germany.; German Center for Diabetes Research (DZD e.V.), Partner Düsseldorf, 85764 Neuherberg, Germany.
Al-Hasani H; Institute for Clinical Biochemistry and Pathobiochemistry, German Diabetes Center (DDZ), Leibniz Center for Diabetes Research at Heinrich Heine University, Medical Faculty, 40225 Düsseldorf, Germany.; German Center for Diabetes Research (DZD e.V.), Partner Düsseldorf, 85764 Neuherberg, Germany.
Chadt A; Institute for Clinical Biochemistry and Pathobiochemistry, German Diabetes Center (DDZ), Leibniz Center for Diabetes Research at Heinrich Heine University, Medical Faculty, 40225 Düsseldorf, Germany.; German Center for Diabetes Research (DZD e.V.), Partner Düsseldorf, 85764 Neuherberg, Germany.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Feb 05; Vol. 25 (3). Date of Electronic Publication: 2024 Feb 05.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Insulin Resistance*
Diabetes Mellitus, Type 2*/metabolism
Humans ; GTPase-Activating Proteins/metabolism ; AMP-Activated Protein Kinases/metabolism ; Muscle, Skeletal/metabolism ; Glucose/metabolism ; Insulin/metabolism ; Phosphorylation ; Insulin, Regular, Human ; Glucose Transporter Type 4/metabolism ; Muscle Contraction

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Skocz do pozycji: 15.

Tytuł:: Manipulation of Sonic Hedgehog Signaling Pathway in Maintenance, Differentiation, and Endocrine Activity of Insulin-Producing Cells: A Systematic Review.
Autorzy:: Dayer D; Cellular and Molecular Research Center, Medical Basic Sciences Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Bayati V; Cellular and Molecular Research Center, Medical Basic Sciences Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.; Department of Anatomy, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Ebrahimi M; Thalassemia and Hemoglobinopathy Research Center, Research Institute of Health, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.; Pokaż więcej
Źródło:: Iranian journal of medical sciences [Iran J Med Sci] 2024 Feb 01; Vol. 49 (2), pp. 65-76. Date of Electronic Publication: 2024 Feb 01 (Print Publication: 2024).
Typ publikacji:: Systematic Review; Journal Article; Review
MeSH Terms:: Hedgehog Proteins*/metabolism
Hedgehog Proteins*/pharmacology
Insulin-Secreting Cells*/metabolism
Insulin/metabolism ; Insulin/pharmacology ; Cell Differentiation/physiology ; Signal Transduction

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Skocz do pozycji: 16.

Tytuł:: The Discovery of New Inhibitors of Insulin-Regulated Aminopeptidase by a High-Throughput Screening of 400,000 Drug-like Compounds.
Autorzy:: Gising J; The Beijer Laboratory, Science for Life Laboratory, Department of Medicinal Chemistry, Biomedical Centre, Uppsala University, P.O. Box 574, SE-751 23 Uppsala, Sweden.
Honarnejad S; Pivot Park Screening Centre, Kloosterstraat 9, 5349 AB Oss, The Netherlands.
Bras M; Pivot Park Screening Centre, Kloosterstraat 9, 5349 AB Oss, The Netherlands.
Baillie GL; BioAscent Discovery Ltd., Bo'Ness Road, Newhouse, Motherwell ML1 5UH, UK.
McElroy SP; BioAscent Discovery Ltd., Bo'Ness Road, Newhouse, Motherwell ML1 5UH, UK.
Jones PS; BioAscent Discovery Ltd., Bo'Ness Road, Newhouse, Motherwell ML1 5UH, UK.
Morrison A; BioAscent Discovery Ltd., Bo'Ness Road, Newhouse, Motherwell ML1 5UH, UK.
Beveridge J; The Beijer Laboratory, Science for Life Laboratory, Department of Medicinal Chemistry, Biomedical Centre, Uppsala University, P.O. Box 574, SE-751 23 Uppsala, Sweden.
Hallberg M; The Beijer Laboratory, Department of Pharmaceutical Biosciences, Neuropharmacology and Addiction Research, Biomedical Centre, Uppsala University, P.O. Box 591, SE-751 24 Uppsala, Sweden.
Larhed M; The Beijer Laboratory, Science for Life Laboratory, Department of Medicinal Chemistry, Biomedical Centre, Uppsala University, P.O. Box 574, SE-751 23 Uppsala, Sweden.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Apr 06; Vol. 25 (7). Date of Electronic Publication: 2024 Apr 06.
Typ publikacji:: Journal Article
MeSH Terms:: Insulin*
Aminopeptidases*
High-Throughput Screening Assays ; Insulin, Regular, Human ; Coloring Agents ; Hydroxamic Acids ; Zinc

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Skocz do pozycji: 17.

Tytuł:: The Lipophilic Extract from Ginkgo biloba L. Leaves Promotes Glucose Uptake and Alleviates Palmitate-Induced Insulin Resistance in C2C12 Myotubes.
Autorzy:: Li T; School of Life Sciences, East China Normal University, 500 Dongchuan Road, Shanghai 200241, China.
Lv Q; School of Life Sciences, East China Normal University, 500 Dongchuan Road, Shanghai 200241, China.
Liu C; China National Institute of Standardization, 4 Zhichun Road, Beijing 100191, China.
Li C; School of Life Sciences, East China Normal University, 500 Dongchuan Road, Shanghai 200241, China.
Xie X; School of Life Sciences, East China Normal University, 500 Dongchuan Road, Shanghai 200241, China.
Zhang W; School of Life Sciences, East China Normal University, 500 Dongchuan Road, Shanghai 200241, China.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2024 Apr 03; Vol. 29 (7). Date of Electronic Publication: 2024 Apr 03.
Typ publikacji:: Journal Article
MeSH Terms:: Ginkgo biloba*
Insulin Resistance*
AMP-Activated Protein Kinases ; Plant Extracts/pharmacology ; Insulin ; Muscle Fibers, Skeletal ; Glucose

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Skocz do pozycji: 18.

Tytuł:: JAK/STAT mediated insulin resistance in muscles is essential for effective immune response.
Autorzy:: McMullen E; Faculty of Science, University of South Bohemia, České Budějovice, Czechia. .
Strych L; Faculty of Science, University of South Bohemia, České Budějovice, Czechia.
Chodakova L; Faculty of Science, University of South Bohemia, České Budějovice, Czechia.
Krebs A; Institute of Neuro- and Behavioral Biology, University of Münster, Münster, Germany.
Dolezal T; Faculty of Science, University of South Bohemia, České Budějovice, Czechia. .; Pokaż więcej
Źródło:: Cell communication and signaling : CCS [Cell Commun Signal] 2024 Apr 02; Vol. 22 (1), pp. 203. Date of Electronic Publication: 2024 Apr 02.
Typ publikacji:: Journal Article
MeSH Terms:: Drosophila Proteins*/metabolism
Insulin Resistance*
Wasps*/metabolism
Animals ; Transcription Factors/metabolism ; Janus Kinases/metabolism ; STAT Transcription Factors/metabolism ; Drosophila/genetics ; Muscles ; Larva/metabolism ; Immunity ; Carbohydrates ; Insulin-Like Growth Factor Binding Proteins/metabolism

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Skocz do pozycji: 19.

Tytuł:: Identification of HDAC9 and ARRDC4 as potential biomarkers and targets for treatment of type 2 diabetes.
Autorzy:: Liu J; Endocrinology Department, The Second Hospital of Hebei Medical University, No.215 Heping West Road, Shijiazhuang, 050000, People's Republic of China.
Meng L; General Medical Department, The Fourth Hospital of Hebei Medical University, No.12 Jiankang Road, Shijiazhuang, 050000, People's Republic of China.
Liu Z; Endocrinology Department, The Second Hospital of Hebei Medical University, No.215 Heping West Road, Shijiazhuang, 050000, People's Republic of China. .
Lu M; Medical Department, The Second Hospital of Hebei Medical University, No.215 Heping West Road, Shijiazhuang, 050000, People's Republic of China.
Wang R; Endocrinology Department, The Second Hospital of Hebei Medical University, No.215 Heping West Road, Shijiazhuang, 050000, People's Republic of China.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Mar 25; Vol. 14 (1), pp. 7083. Date of Electronic Publication: 2024 Mar 25.
Typ publikacji:: Journal Article
MeSH Terms:: Diabetes Mellitus, Type 2*/diagnosis
Diabetes Mellitus, Type 2*/genetics
Histone Deacetylases*/genetics
Histone Deacetylases*/metabolism
Insulin Resistance*/genetics
MicroRNAs*
Animals ; Humans ; Mice ; Biomarkers ; Immunotherapy ; Insulin ; Repressor Proteins/genetics ; Repressor Proteins/metabolism ; Intracellular Signaling Peptides and Proteins/genetics ; Intracellular Signaling Peptides and Proteins/metabolism

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Tytuł:: Inhibition of Insulin-Regulated Aminopeptidase by Imidazo [1,5-α]pyridines-Synthesis and Evaluation.
Autorzy:: Engen K; Department of Medicinal Chemistry, Uppsala University, BMC, P.O. Box 574, SE-751 23 Uppsala, Sweden.
Lundbäck T; Chemical Biology Consortium Sweden (CBCS), Science for Life Laboratory, Department of Medical Biochemistry and Biophysics, Division of Chemical Biology and Genome Engineering, Karolinska Institutet, Tomtebodavägen 23A, SE-171 65 Solna, Sweden.; Mechanistic & Structural Biology, Discovery Sciences, R&D, AstraZeneca, SE-431 83 Mölndal, Sweden.
Yadav A; The Beijer Laboratory, Science for Life Laboratory, Department of Medicinal Chemistry, Uppsala University, BMC, P.O. Box 574, SE-751 23 Uppsala, Sweden.
Puthiyaparambath S; The Beijer Laboratory, Science for Life Laboratory, Department of Medicinal Chemistry, Uppsala University, BMC, P.O. Box 574, SE-751 23 Uppsala, Sweden.
Rosenström U; Department of Medicinal Chemistry, Uppsala University, BMC, P.O. Box 574, SE-751 23 Uppsala, Sweden.
Gising J; The Beijer Laboratory, Science for Life Laboratory, Department of Medicinal Chemistry, Uppsala University, BMC, P.O. Box 574, SE-751 23 Uppsala, Sweden.
Jenmalm-Jensen A; Chemical Biology Consortium Sweden (CBCS), Science for Life Laboratory, Department of Medical Biochemistry and Biophysics, Division of Chemical Biology and Genome Engineering, Karolinska Institutet, Tomtebodavägen 23A, SE-171 65 Solna, Sweden.
Hallberg M; The Beijer Laboratory, Department of Pharmaceutical Biosciences, Neuropharmacology and Addiction Research, Uppsala University, BMC, P.O. Box 591, SE-751 24 Uppsala, Sweden.
Larhed M; The Beijer Laboratory, Science for Life Laboratory, Department of Medicinal Chemistry, Uppsala University, BMC, P.O. Box 574, SE-751 23 Uppsala, Sweden.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Feb 21; Vol. 25 (5). Date of Electronic Publication: 2024 Feb 21.
Typ publikacji:: Journal Article
MeSH Terms:: Insulin*
Aminopeptidases*
Animals ; Insulin, Regular, Human ; CD13 Antigens ; Leucyl Aminopeptidase ; Pyridines

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