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Tytuł :
Chagas disease is not associated with diabetes, metabolic syndrome, insulin resistance and beta cell dysfunction at baseline of Brazilian Longitudinal Study of Adult Health (ELSA-Brasil).
Autorzy :
Resende BAM; Internal Medicine Department, Faculty of Medicine, Faculdade Atenas, Sete Lagoas, Minas Gerais, Brazil.
Beleigoli AMR; College of Nursing and Health Sciences, Flinders University, Adelaide, South Australia, Australia.
Ribeiro ALP; Internal Medicine Department, Faculty of Medicine, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Duncan B; Postgraduate Program in Epidemiology and Hospital de Clínicas de Porto Alegre, Federal University of Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.
Schmidt MI; Postgraduate Program in Epidemiology and Hospital de Clínicas de Porto Alegre, Federal University of Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.
Mill JG; Department of Physiological Sciences, Federal University of Espirito Santo, Vitória, Espírito Santo, Brazil.
Goulart AC; Hospital Universitário, Universidade de São Paulo, São Paulo, São Paulo, Brazil.
Pereira ADC; Laboratorio de Genetica e Cardiologia Molecular, Instituto do Coração, Faculdade de Medicina da Universidade de São Paulo, São Paulo, São Paulo, Brazil.
Barreto SM; Public Health Department, Faculty of Medicine, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Diniz MFHS; Internal Medicine Department, Faculty of Medicine, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil. Electronic address: .
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Źródło :
Parasitology international [Parasitol Int] 2021 Dec; Vol. 85, pp. 102440. Date of Electronic Publication: 2021 Aug 17.
Typ publikacji :
Journal Article
MeSH Terms :
Insulin Resistance*
Chagas Disease/*epidemiology
Diabetes Mellitus, Type 2/*epidemiology
Insulin-Secreting Cells/*pathology
Metabolic Syndrome/*epidemiology
Adult ; Aged ; Brazil/epidemiology ; Chagas Disease/complications ; Cross-Sectional Studies ; Diabetes Mellitus, Type 2/complications ; Female ; Humans ; Incidence ; Longitudinal Studies ; Male ; Metabolic Syndrome/complications ; Middle Aged ; Prevalence
Czasopismo naukowe
Tytuł :
The role and research progress of the balance and interaction between regulatory T cells and other immune cells in obesity with insulin resistance.
Autorzy :
Liu L; Department of Cardiovascular Medicine, The Second Xiangya Hospital, Central South University , Changsha, Hunan, China.
Hu J; Department of Cardiovascular Medicine, The Second Xiangya Hospital, Central South University , Changsha, Hunan, China.
Wang Y; Department of Cardiovascular Medicine, The Second Xiangya Hospital, Central South University , Changsha, Hunan, China.
Lei H; Department of Cardiovascular Medicine, The Second Xiangya Hospital, Central South University , Changsha, Hunan, China.
Xu D; Department of Cardiovascular Medicine, The Second Xiangya Hospital, Central South University , Changsha, Hunan, China.
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Źródło :
Adipocyte [Adipocyte] 2021 Dec; Vol. 10 (1), pp. 66-79.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Insulin Resistance/*immunology
Obesity/*immunology
T-Lymphocytes, Regulatory/*metabolism
Adipose Tissue/immunology ; Adipose Tissue/metabolism ; Animals ; Cell Differentiation/immunology ; Homeostasis ; Humans ; Immunity, Innate/immunology ; Inflammation/metabolism ; Insulin Resistance/physiology ; Lymphocytes/metabolism ; Macrophages/metabolism ; Natural Killer T-Cells/metabolism ; Obesity/physiopathology ; T-Lymphocytes, Regulatory/immunology ; Th1 Cells/immunology ; Th1 Cells/metabolism ; Th17 Cells/immunology ; Th17 Cells/metabolism
Czasopismo naukowe
Tytuł :
Is type 2 diabetes an adiposity-based metabolic disease? From the origin of insulin resistance to the concept of dysfunctional adipose tissue.
Autorzy :
Sbraccia P; Dipartimento di Medicina dei Sistemi, Università di Roma 'Tor Vergata', Via Montpellier, 1, 00133, Rome, Italy. .; Unit of Internal Medicine, Obesity Center, Policlinico Tor Vergata, Rome, Italy. .
D'Adamo M; Dipartimento di Medicina dei Sistemi, Università di Roma 'Tor Vergata', Via Montpellier, 1, 00133, Rome, Italy.; Unit of Internal Medicine, Obesity Center, Policlinico Tor Vergata, Rome, Italy.
Guglielmi V; Dipartimento di Medicina dei Sistemi, Università di Roma 'Tor Vergata', Via Montpellier, 1, 00133, Rome, Italy.; Unit of Internal Medicine, Obesity Center, Policlinico Tor Vergata, Rome, Italy.
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Źródło :
Eating and weight disorders : EWD [Eat Weight Disord] 2021 Dec; Vol. 26 (8), pp. 2429-2441. Date of Electronic Publication: 2021 Feb 08.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Diabetes Mellitus, Type 2*
Insulin Resistance*
Adipose Tissue ; Adiposity ; Genome-Wide Association Study ; Humans
Czasopismo naukowe
Tytuł :
Insulin resistance as a marker for the immune-metabolic subtype of depression.
Autorzy :
Brouwer A; Amsterdam UMC and GGZ inGeest, Dept. of Psychiatry, Amsterdam Public Health Research Institute, Vrije Universiteit, De Boelelaan 1117, 1081 HV, Postbus, 7075, 1007 MB, Amsterdam, the Netherlands. Electronic address: .
van Raalte DH; Amsterdam UMC, Dept. of Internal Medicine, Diabetes Center, Vrije Universiteit, Amsterdam, the Netherlands.
Lamers F; Amsterdam UMC and GGZ inGeest, Dept. of Psychiatry, Amsterdam Public Health Research Institute, Vrije Universiteit, De Boelelaan 1117, 1081 HV, Postbus, 7075, 1007 MB, Amsterdam, the Netherlands.
Rutters F; Amsterdam UMC, Dept. of Epidemiology and Biostatistics, Amsterdam Public Health Research Institute, Vrije Universiteit, Amsterdam, the Netherlands.
Elders PJM; Amsterdam UMC, Dept. of General Practice and Elderly Care Medicine, Amsterdam Public Health Research Institute, Vrije Universiteit, Amsterdam, the Netherlands.
Van Someren EJW; Amsterdam UMC and GGZ inGeest, Dept. of Psychiatry, Amsterdam Public Health Research Institute, Vrije Universiteit, De Boelelaan 1117, 1081 HV, Postbus, 7075, 1007 MB, Amsterdam, the Netherlands; Dept. of Sleep and Cognition, Netherlands Institute for Neuroscience, Amsterdam, the Netherlands; Amsterdam UMC, Dept. of Integrative Neurophysiology, Centre for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, Vrije Universiteit, Amsterdam, the Netherlands.
Snoek FJ; Amsterdam UMC, Dept. of Medical Psychology, Amsterdam Public Health research institute, Vrije Universiteit and University of Amsterdam, Amsterdam, the Netherlands.
Beekman ATF; Amsterdam UMC and GGZ inGeest, Dept. of Psychiatry, Amsterdam Public Health Research Institute, Vrije Universiteit, De Boelelaan 1117, 1081 HV, Postbus, 7075, 1007 MB, Amsterdam, the Netherlands.
Bremmer MA; Amsterdam UMC and GGZ inGeest, Dept. of Psychiatry, Amsterdam Public Health Research Institute, Vrije Universiteit, De Boelelaan 1117, 1081 HV, Postbus, 7075, 1007 MB, Amsterdam, the Netherlands.
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Źródło :
Journal of affective disorders [J Affect Disord] 2021 Dec 01; Vol. 295, pp. 1371-1376. Date of Electronic Publication: 2021 Sep 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Diabetes Mellitus, Type 2*/complications
Diabetes Mellitus, Type 2*/therapy
Insulin Resistance*
Affect ; Antidepressive Agents ; Depression/therapy ; Humans
Czasopismo naukowe
Tytuł :
Evaluation of therapeutic effect of Premna herbacea in diabetic rat and isoverbascoside against insulin resistance in L6 muscle cells through bioenergetics and stimulation of JNK and AKT/mTOR signaling cascade.
Autorzy :
Kashyap B; Biochemistry and Drug Discovery Lab - I, Life Science Division, Institute of Advanced Study in Science and Technology (IASST), Vigyan Path, Paschim Boragaon, Garchuk- 781035, Guwahati, Assam, India; Department of Molecular Biology and Biotechnology, Cotton University, Panbazar, Guwahati-781001, Assam, India.
Barge SR; Biochemistry and Drug Discovery Lab - I, Life Science Division, Institute of Advanced Study in Science and Technology (IASST), Vigyan Path, Paschim Boragaon, Garchuk- 781035, Guwahati, Assam, India; Department of Molecular Biology and Biotechnology, Cotton University, Panbazar, Guwahati-781001, Assam, India.
Bharadwaj S; Biochemistry and Drug Discovery Lab - I, Life Science Division, Institute of Advanced Study in Science and Technology (IASST), Vigyan Path, Paschim Boragaon, Garchuk- 781035, Guwahati, Assam, India; Department of Molecular Biology and Biotechnology, Cotton University, Panbazar, Guwahati-781001, Assam, India.
Deka B; Biochemistry and Drug Discovery Lab - I, Life Science Division, Institute of Advanced Study in Science and Technology (IASST), Vigyan Path, Paschim Boragaon, Garchuk- 781035, Guwahati, Assam, India; Department of Molecular Biology and Biotechnology, Cotton University, Panbazar, Guwahati-781001, Assam, India.
Rahman S; Biochemistry and Drug Discovery Lab - I, Life Science Division, Institute of Advanced Study in Science and Technology (IASST), Vigyan Path, Paschim Boragaon, Garchuk- 781035, Guwahati, Assam, India; Assam down town University, Sankar Madhab Path, Gandhi Nagar, Panikhaiti, Guwahati, Assam, India.
Ghosh A; Biochemistry and Drug Discovery Lab - I, Life Science Division, Institute of Advanced Study in Science and Technology (IASST), Vigyan Path, Paschim Boragaon, Garchuk- 781035, Guwahati, Assam, India.
Manna P; Biochemistry and Drug Discovery Lab - I, Life Science Division, Institute of Advanced Study in Science and Technology (IASST), Vigyan Path, Paschim Boragaon, Garchuk- 781035, Guwahati, Assam, India; CSIR-North East Institute of Science and Technology, Biological Science and Technology Division, Jorhat, Assam, 785006, India.
Dutta PP; Biochemistry and Drug Discovery Lab - I, Life Science Division, Institute of Advanced Study in Science and Technology (IASST), Vigyan Path, Paschim Boragaon, Garchuk- 781035, Guwahati, Assam, India; Assam down town University, Sankar Madhab Path, Gandhi Nagar, Panikhaiti, Guwahati, Assam, India.
Sheikh Y; Biochemistry and Drug Discovery Lab - I, Life Science Division, Institute of Advanced Study in Science and Technology (IASST), Vigyan Path, Paschim Boragaon, Garchuk- 781035, Guwahati, Assam, India.
Kandimalla R; Biochemistry and Drug Discovery Lab - I, Life Science Division, Institute of Advanced Study in Science and Technology (IASST), Vigyan Path, Paschim Boragaon, Garchuk- 781035, Guwahati, Assam, India.
Samanta SK; Biochemistry and Drug Discovery Lab - I, Life Science Division, Institute of Advanced Study in Science and Technology (IASST), Vigyan Path, Paschim Boragaon, Garchuk- 781035, Guwahati, Assam, India.
Boruwa J; Biochemistry and Drug Discovery Lab - I, Life Science Division, Institute of Advanced Study in Science and Technology (IASST), Vigyan Path, Paschim Boragaon, Garchuk- 781035, Guwahati, Assam, India.
Saikia S; Biochemistry and Drug Discovery Lab - I, Life Science Division, Institute of Advanced Study in Science and Technology (IASST), Vigyan Path, Paschim Boragaon, Garchuk- 781035, Guwahati, Assam, India.
Swargiary D; Biochemistry and Drug Discovery Lab - I, Life Science Division, Institute of Advanced Study in Science and Technology (IASST), Vigyan Path, Paschim Boragaon, Garchuk- 781035, Guwahati, Assam, India.
Kamboj P; Drug Discovery Research Centre, Translational Health Science and Technology Institute (THSTI), Faridabad - 121001, Haryana, India.
Tuli D; Drug Discovery Research Centre, Translational Health Science and Technology Institute (THSTI), Faridabad - 121001, Haryana, India.
Pal U; S.N. Bose National Centre for Basic Sciences, JD Block, Sector III, Salt Lake City, Kolkata 700106, West Bengal, India.
Borah JC; Biochemistry and Drug Discovery Lab - I, Life Science Division, Institute of Advanced Study in Science and Technology (IASST), Vigyan Path, Paschim Boragaon, Garchuk- 781035, Guwahati, Assam, India. Electronic address: .
Banerjee SK; Drug Discovery Research Centre, Translational Health Science and Technology Institute (THSTI), Faridabad - 121001, Haryana, India. Electronic address: .
Talukdar NC; Biochemistry and Drug Discovery Lab - I, Life Science Division, Institute of Advanced Study in Science and Technology (IASST), Vigyan Path, Paschim Boragaon, Garchuk- 781035, Guwahati, Assam, India; Assam down town University, Sankar Madhab Path, Gandhi Nagar, Panikhaiti, Guwahati, Assam, India.. Electronic address: .
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Źródło :
Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2021 Dec; Vol. 93, pp. 153761. Date of Electronic Publication: 2021 Sep 22.
Typ publikacji :
Journal Article
MeSH Terms :
Diabetes Mellitus, Type 2*/drug therapy
Insulin Resistance*
Animals ; Energy Metabolism ; Glucose ; Glucosides ; Insulin/metabolism ; Male ; Molecular Docking Simulation ; Muscle Cells/metabolism ; Phenols ; Proto-Oncogene Proteins c-akt/metabolism ; Rats ; Rats, Sprague-Dawley ; TOR Serine-Threonine Kinases/metabolism
Czasopismo naukowe
Tytuł :
Serum branched-chain amino acids modifies the associations between air pollutants and insulin resistance.
Autorzy :
Shi Y; State Key Joint Laboratory of Environmental Simulation and Pollution Control, International Joint Laboratory for Regional Pollution Control (IJRC), Ministry of Education, College of Environmental Sciences and Engineering, Beijing 100871, China.
Han Y; State Key Joint Laboratory of Environmental Simulation and Pollution Control, International Joint Laboratory for Regional Pollution Control (IJRC), Ministry of Education, College of Environmental Sciences and Engineering, Beijing 100871, China; Environmental Research Group, MRC Centre for Environment and Health, Imperial College London, London, UK.
Wang Y; State Key Joint Laboratory of Environmental Simulation and Pollution Control, International Joint Laboratory for Regional Pollution Control (IJRC), Ministry of Education, College of Environmental Sciences and Engineering, Beijing 100871, China; National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China.
Qi L; State Key Joint Laboratory of Environmental Simulation and Pollution Control, International Joint Laboratory for Regional Pollution Control (IJRC), Ministry of Education, College of Environmental Sciences and Engineering, Beijing 100871, China; School of Food and Biological Engineering, Shaanxi University of Science & Technology, Xi'an 710021, China.
Chen X; State Key Joint Laboratory of Environmental Simulation and Pollution Control, International Joint Laboratory for Regional Pollution Control (IJRC), Ministry of Education, College of Environmental Sciences and Engineering, Beijing 100871, China; Hebei Xiongan Green-Research Inspection and Certification Co., Ltd., Shenzhen Institute of Building Research Co., Ltd., Shenzhen, China.
Chen W; State Key Joint Laboratory of Environmental Simulation and Pollution Control, International Joint Laboratory for Regional Pollution Control (IJRC), Ministry of Education, College of Environmental Sciences and Engineering, Beijing 100871, China.
Li W; Peking University Hospital, Peking University, Beijing 100871, China.
Zhang H; Peking University Hospital, Peking University, Beijing 100871, China.
Zhu T; State Key Joint Laboratory of Environmental Simulation and Pollution Control, International Joint Laboratory for Regional Pollution Control (IJRC), Ministry of Education, College of Environmental Sciences and Engineering, Beijing 100871, China.
Gong J; State Key Joint Laboratory of Environmental Simulation and Pollution Control, International Joint Laboratory for Regional Pollution Control (IJRC), Ministry of Education, College of Environmental Sciences and Engineering, Beijing 100871, China. Electronic address: .
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Źródło :
Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2021 Dec 01; Vol. 225, pp. 112780. Date of Electronic Publication: 2021 Sep 16.
Typ publikacji :
Journal Article
MeSH Terms :
Air Pollutants*/analysis
Air Pollutants*/toxicity
Diabetes Mellitus, Type 2*/chemically induced
Insulin Resistance*
Aged ; Amino Acids, Branched-Chain ; Environmental Exposure/analysis ; Humans
Czasopismo naukowe
Tytuł :
Comparative evaluation for phytochemical composition and regulation of blood glucose, hepatic oxidative stress and insulin resistance in mice and HepG2 models of four typical Chinese dark teas.
Autorzy :
Zhu J; Institute of Food Engineering, College of Life Science, Shanghai Normal University, Shanghai, China.
Yu C; Institute of Food Engineering, College of Life Science, Shanghai Normal University, Shanghai, China.
Zhou H; Institute of Food Engineering, College of Life Science, Shanghai Normal University, Shanghai, China.
Wei X; Institute of Food Engineering, College of Life Science, Shanghai Normal University, Shanghai, China.; Department of Food Science & Technology, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, China.
Wang Y; Institute of Food Engineering, College of Life Science, Shanghai Normal University, Shanghai, China.
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Źródło :
Journal of the science of food and agriculture [J Sci Food Agric] 2021 Dec; Vol. 101 (15), pp. 6563-6577. Date of Electronic Publication: 2021 May 31.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Insulin Resistance*
Blood Glucose/*metabolism
Camellia sinensis/*metabolism
Diabetes Mellitus, Type 2/*diet therapy
Hypoglycemic Agents/*metabolism
Liver/*metabolism
Phytochemicals/*metabolism
Animals ; Antioxidants/chemistry ; Antioxidants/metabolism ; Camellia sinensis/chemistry ; China ; Diabetes Mellitus, Type 2/genetics ; Diabetes Mellitus, Type 2/metabolism ; Glycoside Hydrolases/genetics ; Glycoside Hydrolases/metabolism ; Hep G2 Cells ; Humans ; Hypoglycemic Agents/chemistry ; Male ; Mice ; Mice, Inbred C57BL ; Oxidative Stress ; Peroxisome Proliferator-Activated Receptors/genetics ; Peroxisome Proliferator-Activated Receptors/metabolism ; Phytochemicals/chemistry ; Plant Extracts/chemistry ; Plant Extracts/metabolism ; Tea
Czasopismo naukowe
Tytuł :
The interplay among oxidative stress, brain insulin resistance and AMPK dysfunction contribute to neurodegeneration in type 2 diabetes and Alzheimer disease.
Autorzy :
Barone E; Department of Biochemical Sciences 'A. Rossi-Fanelli', Sapienza University of Rome, Piazzale A. Moro 5, 00185, Roma, Italy.
Di Domenico F; Department of Biochemical Sciences 'A. Rossi-Fanelli', Sapienza University of Rome, Piazzale A. Moro 5, 00185, Roma, Italy.
Perluigi M; Department of Biochemical Sciences 'A. Rossi-Fanelli', Sapienza University of Rome, Piazzale A. Moro 5, 00185, Roma, Italy.
Butterfield DA; Department of Chemistry and Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY, 40506-0055, USA. Electronic address: .
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Źródło :
Free radical biology & medicine [Free Radic Biol Med] 2021 Nov 20; Vol. 176, pp. 16-33. Date of Electronic Publication: 2021 Sep 14.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms :
Alzheimer Disease*
Diabetes Mellitus, Type 2*/complications
Insulin Resistance*
AMP-Activated Protein Kinases/genetics ; Aged ; Brain ; Humans ; Oxidative Stress
Czasopismo naukowe
Tytuł :
Independent associations of thyroid-related hormones with hepatic steatosis and insulin resistance in euthyroid overweight/obese Chinese adults.
Autorzy :
Ma D; School of Medicine, Xiamen University, Xiamen, China.
Zeng J; Department of Endocrinology and Diabetes, The First Affiliated Hospital, Xiamen University, Xiamen, China.; Xiamen Clinical Medical Center for Endocrine and Metabolic Diseases, Xiamen, China.
Huang B; Department of Endocrinology and Diabetes, The First Affiliated Hospital, Xiamen University, Xiamen, China.; Xiamen Clinical Medical Center for Endocrine and Metabolic Diseases, Xiamen, China.
Yan F; Department of Endocrinology and Diabetes, The First Affiliated Hospital, Xiamen University, Xiamen, China.; Xiamen Clinical Medical Center for Endocrine and Metabolic Diseases, Xiamen, China.
Ye J; The Third Clinical Medical College, Fujian Medical University, Fuzhou, China.
Chen Y; The Third Clinical Medical College, Fujian Medical University, Fuzhou, China.
Zeng X; The Third Clinical Medical College, Fujian Medical University, Fuzhou, China.
Zheng X; Department of Endocrinology and Diabetes, The First Affiliated Hospital, Xiamen University, Xiamen, China.; Xiamen Clinical Medical Center for Endocrine and Metabolic Diseases, Xiamen, China.
Xiao F; Department of Endocrinology and Diabetes, The First Affiliated Hospital, Xiamen University, Xiamen, China.; Xiamen Clinical Medical Center for Endocrine and Metabolic Diseases, Xiamen, China.
Lin M; Department of Endocrinology and Diabetes, The First Affiliated Hospital, Xiamen University, Xiamen, China.; Xiamen Clinical Medical Center for Endocrine and Metabolic Diseases, Xiamen, China.
Liu C; Department of Endocrinology and Diabetes, The First Affiliated Hospital, Xiamen University, Xiamen, China. .; Xiamen Clinical Medical Center for Endocrine and Metabolic Diseases, Xiamen, China. .; Fujian Province Key Laboratory of Diabetes Translational Medicine, Xiamen, China. .
Li Z; Epidemiology Research Unit, Translational Medical Research Center, The First Affiliated Hospital, Xiamen University, Xiamen, China. .
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Źródło :
BMC gastroenterology [BMC Gastroenterol] 2021 Nov 18; Vol. 21 (1), pp. 431. Date of Electronic Publication: 2021 Nov 18.
Typ publikacji :
Journal Article
MeSH Terms :
Fatty Liver*
Insulin Resistance*
Adult ; China ; Cross-Sectional Studies ; Humans ; Obesity/complications ; Overweight/complications ; Thyroid Gland ; Thyroid Hormones ; Thyrotropin ; Thyroxine ; Triiodothyronine
Czasopismo naukowe
Tytuł :
Programmed cell death 5 improves skeletal muscle insulin resistance by inhibiting IRS-1 ubiquitination through stabilization of MDM2.
Autorzy :
Li B; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, P.R. China.
Ye J; Trauma Medicine Center, Peking University People's Hospital; Key Laboratory of Trauma and Neural Regeneration (Peking University), National Center for Trauma Medicine, Beijing 100044, P.R. China; Department of Central Laboratory & Institute of Clinical Molecular Biology, Peking University People's Hospital, Beijing 100044, P.R. China.
Liu R; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, P.R. China.
Weng L; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, P.R. China.
Cao Y; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, P.R. China.
Jia S; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, P.R. China.
Xu C; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, P.R. China.
Liu Y; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, P.R. China.
Yan S; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, P.R. China.
Zheng M; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, P.R. China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Nov 15; Vol. 285, pp. 119918. Date of Electronic Publication: 2021 Sep 01.
Typ publikacji :
Journal Article
MeSH Terms :
Insulin Resistance*
Ubiquitination*
Apoptosis Regulatory Proteins/*physiology
Insulin Receptor Substrate Proteins/*metabolism
Neoplasm Proteins/*physiology
Proto-Oncogene Proteins c-mdm2/*metabolism
Animals ; Apoptosis Regulatory Proteins/genetics ; Cell Differentiation ; Cell Line ; Diet, High-Fat ; Disease Models, Animal ; Enzyme Stability ; Gene Knockdown Techniques ; Male ; Mice ; Mice, Inbred C57BL ; Muscle Fibers, Skeletal/cytology ; Myoblasts/cytology ; Myoblasts/drug effects ; Neoplasm Proteins/genetics ; Obesity/genetics ; Obesity/metabolism ; Palmitates/pharmacology ; Proteolysis/drug effects
Czasopismo naukowe
Tytuł :
Efficacy of Bushen Huatan Decoction combined with Baduanjin in the treatment of polycystic ovary syndrome with insulin resistance (IR-PCOS), kidney deficiency and phlegm dampness: study protocol for a randomized controlled trial.
Autorzy :
Qian H; Department of Reproduction, Zhangjiagang TCM Hospital Affiliated to Nanjing University of Chinese Medicine, Zhangjiagang, Suzhou, Jiangsu, China.
Xu W; Department of Reproduction, Zhangjiagang TCM Hospital Affiliated to Nanjing University of Chinese Medicine, Zhangjiagang, Suzhou, Jiangsu, China.
Cui L; Department of Pathology, Zhangjiagang TCM Hospital Affiliated to Nanjing University of Chinese Medicine, Zhangjiagang, Suzhou, Jiangsu, China.
Wang R; Department of Laboratory Medicine, Zhangjiagang TCM Hospital Affiliated to Nanjing University of Chinese Medicine, Zhangjiagang, Suzhou, Jiangsu, China.
Wang J; Department of Reproduction, Zhangjiagang TCM Hospital Affiliated to Nanjing University of Chinese Medicine, Zhangjiagang, Suzhou, Jiangsu, China.
Tang M; Department of Reproduction, Zhangjiagang TCM Hospital Affiliated to Nanjing University of Chinese Medicine, Zhangjiagang, Suzhou, Jiangsu, China.
Wei M; The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China. .
Wang L; Department of Reproduction, Zhangjiagang TCM Hospital Affiliated to Nanjing University of Chinese Medicine, Zhangjiagang, Suzhou, Jiangsu, China. .
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Źródło :
Trials [Trials] 2021 Nov 07; Vol. 22 (1), pp. 781. Date of Electronic Publication: 2021 Nov 07.
Typ publikacji :
Clinical Trial Protocol; Journal Article
MeSH Terms :
Insulin Resistance*
Metabolic Syndrome*
Metformin*
Polycystic Ovary Syndrome*/diagnosis
Polycystic Ovary Syndrome*/drug therapy
Female ; Humans ; Insulin ; Kidney ; Pregnancy ; Randomized Controlled Trials as Topic
Czasopismo naukowe
Tytuł :
[Effects of Metformin and Sitagliptin on islet cell function in insulin-resistant prediabetic KKay mice].
Autorzy :
Li P; Department of Rheumatology, the General Hospital of Northern Theater Command, Shenyang 110812.
Liang LL; Department of Endocrinology, Shenyang 110812, China.
Wang Y; Department of Endocrinology, Shenyang 110812, China.
Hou D; Department of Endocrinology, Shenyang 110812, China.
Yang X; Department of Endocrinology, Shenyang 110812, China.
Yang B; Department of Endocrinology, Shenyang 110812, China.
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Źródło :
Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology [Zhongguo Ying Yong Sheng Li Xue Za Zhi] 2021 Nov; Vol. 37 (6), pp. 644-649.
Typ publikacji :
Journal Article
MeSH Terms :
Diabetes Mellitus, Type 2*/drug therapy
Insulin Resistance*
Islets of Langerhans*
Metformin*/pharmacology
Prediabetic State*
Animals ; Blood Glucose ; Insulin ; Mice ; Sitagliptin Phosphate/pharmacology
Czasopismo naukowe
Tytuł :
Statins Are Associated With Increased Insulin Resistance and Secretion.
Autorzy :
Abbasi F; Division of Cardiovascular Medicine (F. Abbasi, C.L., C.S.H., V.H., P.T., F. Abbas, G.M.R., J.W.K.), Stanford University, CA.; Cardiovascular Institute (F. Abbasi, C.L., C.S.H., V.H., M.-S.T., P.T., F. Abbas, G.M.R., M.P.S., J.W.K.), Stanford University, CA.; Department of Medicine (F. Abbasi, C.L., C.S.H., V.H., F.A., G.M.R., S.H.K., J.W.K.), Stanford University, CA.; Stanford Diabetes Research Center (F.A., M.-S.T., M.P.S., S.H.K., J.W.K.), Stanford University, CA.
Lamendola C; Division of Cardiovascular Medicine (F. Abbasi, C.L., C.S.H., V.H., P.T., F. Abbas, G.M.R., J.W.K.), Stanford University, CA.; Cardiovascular Institute (F. Abbasi, C.L., C.S.H., V.H., M.-S.T., P.T., F. Abbas, G.M.R., M.P.S., J.W.K.), Stanford University, CA.; Department of Medicine (F. Abbasi, C.L., C.S.H., V.H., F.A., G.M.R., S.H.K., J.W.K.), Stanford University, CA.
Harris CS; Division of Cardiovascular Medicine (F. Abbasi, C.L., C.S.H., V.H., P.T., F. Abbas, G.M.R., J.W.K.), Stanford University, CA.; Department of Medicine (F. Abbasi, C.L., C.S.H., V.H., F.A., G.M.R., S.H.K., J.W.K.), Stanford University, CA.
Harris V; Division of Cardiovascular Medicine (F. Abbasi, C.L., C.S.H., V.H., P.T., F. Abbas, G.M.R., J.W.K.), Stanford University, CA.; Cardiovascular Institute (F. Abbasi, C.L., C.S.H., V.H., M.-S.T., P.T., F. Abbas, G.M.R., M.P.S., J.W.K.), Stanford University, CA.; Department of Medicine (F. Abbasi, C.L., C.S.H., V.H., F.A., G.M.R., S.H.K., J.W.K.), Stanford University, CA.
Tsai MS; Cardiovascular Institute (F. Abbasi, C.L., C.S.H., V.H., M.-S.T., P.T., F. Abbas, G.M.R., M.P.S., J.W.K.), Stanford University, CA.; Department of Genetics (M.-S.T., M.P.S.), Stanford University, CA.; Stanford Diabetes Research Center (F.A., M.-S.T., M.P.S., S.H.K., J.W.K.), Stanford University, CA.
Tripathi P; Division of Cardiovascular Medicine (F. Abbasi, C.L., C.S.H., V.H., P.T., F. Abbas, G.M.R., J.W.K.), Stanford University, CA.; Cardiovascular Institute (F. Abbasi, C.L., C.S.H., V.H., M.-S.T., P.T., F. Abbas, G.M.R., M.P.S., J.W.K.), Stanford University, CA.
Abbas F; Division of Cardiovascular Medicine (F. Abbasi, C.L., C.S.H., V.H., P.T., F. Abbas, G.M.R., J.W.K.), Stanford University, CA.; Cardiovascular Institute (F. Abbasi, C.L., C.S.H., V.H., M.-S.T., P.T., F. Abbas, G.M.R., M.P.S., J.W.K.), Stanford University, CA.; Department of Medicine (F. Abbasi, C.L., C.S.H., V.H., F.A., G.M.R., S.H.K., J.W.K.), Stanford University, CA.
Reaven GM; Division of Cardiovascular Medicine (F. Abbasi, C.L., C.S.H., V.H., P.T., F. Abbas, G.M.R., J.W.K.), Stanford University, CA.; Cardiovascular Institute (F. Abbasi, C.L., C.S.H., V.H., M.-S.T., P.T., F. Abbas, G.M.R., M.P.S., J.W.K.), Stanford University, CA.; Department of Medicine (F. Abbasi, C.L., C.S.H., V.H., F.A., G.M.R., S.H.K., J.W.K.), Stanford University, CA.
Reaven PD; University of Arizona and Phoenix VA Health Care System (P.D.R.).
Snyder MP; Cardiovascular Institute (F. Abbasi, C.L., C.S.H., V.H., M.-S.T., P.T., F. Abbas, G.M.R., M.P.S., J.W.K.), Stanford University, CA.; Department of Genetics (M.-S.T., M.P.S.), Stanford University, CA.; Stanford Diabetes Research Center (F.A., M.-S.T., M.P.S., S.H.K., J.W.K.), Stanford University, CA.
Kim SH; Department of Medicine (F. Abbasi, C.L., C.S.H., V.H., F.A., G.M.R., S.H.K., J.W.K.), Stanford University, CA.; Stanford Diabetes Research Center (F.A., M.-S.T., M.P.S., S.H.K., J.W.K.), Stanford University, CA.; Division of Endocrinology, Gerontology and Metabolism (S.H.K.), Stanford University, CA.
Knowles JW; Division of Cardiovascular Medicine (F. Abbasi, C.L., C.S.H., V.H., P.T., F. Abbas, G.M.R., J.W.K.), Stanford University, CA.; Cardiovascular Institute (F. Abbasi, C.L., C.S.H., V.H., M.-S.T., P.T., F. Abbas, G.M.R., M.P.S., J.W.K.), Stanford University, CA.; Department of Medicine (F. Abbasi, C.L., C.S.H., V.H., F.A., G.M.R., S.H.K., J.W.K.), Stanford University, CA.; Stanford Diabetes Research Center (F.A., M.-S.T., M.P.S., S.H.K., J.W.K.), Stanford University, CA.; Stanford Prevention Research Center (J.W.K.), Stanford University, CA.
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Źródło :
Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2021 Nov; Vol. 41 (11), pp. 2786-2797. Date of Electronic Publication: 2021 Aug 26.
Typ publikacji :
Clinical Trial; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Insulin Resistance*
Atorvastatin/*adverse effects
Blood Glucose/*metabolism
Diabetes Mellitus/*chemically induced
Dyslipidemias/*drug therapy
Hydroxymethylglutaryl-CoA Reductase Inhibitors/*adverse effects
Insulin/*blood
Lipids/*blood
Adult ; Aged ; Biomarkers/blood ; Diabetes Mellitus/blood ; Diabetes Mellitus/diagnosis ; Dyslipidemias/blood ; Dyslipidemias/diagnosis ; Female ; Humans ; Male ; Middle Aged ; Prospective Studies ; Risk Assessment ; Risk Factors ; Time Factors ; Treatment Outcome
Czasopismo naukowe
Tytuł :
PPAR-γ-induced changes in visceral fat and adiponectin levels are associated with improvement of steatohepatitis in patients with NASH.
Autorzy :
Gastaldelli A; Diabetes Division, The University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.; Institute of Clinical Physiology, National Research Council, CNR, Pisa, Italy.
Sabatini S; Institute of Clinical Physiology, National Research Council, CNR, Pisa, Italy.; Università degli Studi di Siena, Siena, Italy.
Carli F; Institute of Clinical Physiology, National Research Council, CNR, Pisa, Italy.
Gaggini M; Institute of Clinical Physiology, National Research Council, CNR, Pisa, Italy.
Bril F; Division of Endocrinology, Diabetes and Metabolism, University of Florida, Gainesville, FL, USA.
Belfort-DeAguiar R; Department of Internal Medicine and Endocrinology, Yale University School of Medicine, New Haven, CT, USA.
Positano V; Fondazione Toscana Gabriele Monasterio, Pisa, Italy.
Barb D; Division of Endocrinology, Diabetes and Metabolism, University of Florida, Gainesville, FL, USA.
Kadiyala S; Division of Endocrinology, Diabetes and Metabolism, University of Florida, Gainesville, FL, USA.; Division of Endocrinology, Diabetes and Metabolism, Malcom Randall Veteran Administration Medical Center at Gainesville, Gainesville, FL, USA.
Harrison S; Pinnacle Clinical Research Group, San Antonio, TX, USA.
Cusi K; Division of Endocrinology, Diabetes and Metabolism, University of Florida, Gainesville, FL, USA.; Division of Endocrinology, Diabetes and Metabolism, Malcom Randall Veteran Administration Medical Center at Gainesville, Gainesville, FL, USA.
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Źródło :
Liver international : official journal of the International Association for the Study of the Liver [Liver Int] 2021 Nov; Vol. 41 (11), pp. 2659-2670. Date of Electronic Publication: 2021 Jul 21.
Typ publikacji :
Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Insulin Resistance*
Non-alcoholic Fatty Liver Disease*/drug therapy
Thiazolidinediones*/therapeutic use
Adiponectin ; Diet, Reducing ; Humans ; Hypoglycemic Agents/therapeutic use ; Intra-Abdominal Fat ; Liver ; Obesity ; PPAR gamma
Czasopismo naukowe
Tytuł :
Statin-Related New-Onset Diabetes Appears Driven by Increased Insulin Resistance: Are There Clinical Implications?
Autorzy :
Brinton EA; Utah Lipid Center, Salt Lake City.
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Źródło :
Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2021 Nov; Vol. 41 (11), pp. 2798-2801. Date of Electronic Publication: 2021 Oct 27.
Typ publikacji :
Editorial; Comment
MeSH Terms :
Cardiovascular Diseases*
Diabetes Mellitus, Type 2*/diagnosis
Diabetes Mellitus, Type 2*/drug therapy
Diabetes Mellitus, Type 2*/epidemiology
Hydroxymethylglutaryl-CoA Reductase Inhibitors*/adverse effects
Hyperinsulinism*
Insulin Resistance*
Humans
Opinia redakcyjna
Tytuł :
Aqueous Azadirachta indica (Neem) Extract Attenuates Insulin Resistance to Improve Glycemic Control and Endothelial Function in Subjects with Metabolic Syndrome.
Autorzy :
Pingali U; Department of Clinical Pharmacology & Therapeutics, Nizam's Institute of Medical Sciences, Hyderabad, India.
Vuppalanchi B; Department of Clinical Pharmacology & Therapeutics, Nizam's Institute of Medical Sciences, Hyderabad, India.
Nutalapati C; Department of Clinical Pharmacology & Therapeutics, Nizam's Institute of Medical Sciences, Hyderabad, India.
Gundagani S; Department of Clinical Pharmacology & Therapeutics, Nizam's Institute of Medical Sciences, Hyderabad, India.
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Źródło :
Journal of medicinal food [J Med Food] 2021 Nov; Vol. 24 (11), pp. 1135-1144. Date of Electronic Publication: 2021 Sep 28.
Typ publikacji :
Journal Article; Randomized Controlled Trial
MeSH Terms :
Azadirachta*
Insulin Resistance*
Metabolic Syndrome*/drug therapy
Glycemic Control ; Humans ; Plant Extracts
Czasopismo naukowe
Tytuł :
Curcumin Derivative MTH-3 Regulates Palmitate-induced Insulin Resistance in Mouse Myoblast C 2 C 12 Cells.
Autorzy :
Chiu YJ; Division of Plastic and Reconstructive Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei, Taiwan, R.O.C.; Department of Surgery, School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, R.O.C.; Institute of Clinical Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, R.O.C.
Lo YH; Department of Biological Science and Technology, China Medical University, Taichung, Taiwan, R.O.C.; Department of Medical Research, China Medical University Hospital, China Medical University, Taichung, Taiwan, R.O.C.
Yang JS; Department of Medical Research, China Medical University Hospital, China Medical University, Taichung, Taiwan, R.O.C.
Kuo SC; Chinese Medicinal Research and Development Center, China Medical University Hospital, School of Pharmacy, China Medical University, Taichung, Taiwan, R.O.C.
Tsai SC; Department of Biological Science and Technology, China Medical University, Taichung, Taiwan, R.O.C.; .
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Źródło :
In vivo (Athens, Greece) [In Vivo] 2021 Nov-Dec; Vol. 35 (6), pp. 3181-3191.
Typ publikacji :
Journal Article
MeSH Terms :
Curcumin*/pharmacology
Insulin Resistance*
Animals ; Cell Line ; Insulin ; Mice ; Myoblasts ; Palmitates
Czasopismo naukowe
Tytuł :
Current and emerging gluconeogenesis inhibitors for the treatment of Type 2 diabetes.
Autorzy :
Rendell MS; The Association of Diabetes Investigators, Newport Coast, California, United States.; The Rose Salter Medical Research Foundation, Newport Coast, California, United States.
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Źródło :
Expert opinion on pharmacotherapy [Expert Opin Pharmacother] 2021 Nov; Vol. 22 (16), pp. 2167-2179. Date of Electronic Publication: 2021 Aug 05.
Typ publikacji :
Journal Article
MeSH Terms :
Diabetes Mellitus, Type 2*/drug therapy
Diabetes Mellitus, Type 2*/metabolism
Insulin Resistance*
Gluconeogenesis ; Glucose/metabolism ; Humans ; Insulin/metabolism ; Liver/metabolism
Czasopismo naukowe
Tytuł :
Docking protein 1 and free fatty acids are associated with insulin resistance in patients with type 2 diabetes mellitus.
Autorzy :
Ha X; Department of Clinical Laboratory, The People's Liberation Army Joint Service Support Unit 940 Hospital, Lanzhou, China.; The Second Hospital of Lanzhou University, Lanzhou, China.
Cai X; Department of Medical Laboratory, Qinghai Provincial People's Hospital, Xining, China.
Cao H; The Second Medical Centre of the Chinese People's Liberation Army General Hospital, Beijing, China.
Li J; The First People's Hospital of Baiyin, China.
Yang B; Department of Obstetrics and Gynaecology, Reproductive Medicine Centre, The First Affiliated Hospital of Anhui Medical University, Anhui, China.
Jiang R; Department of Haematology, Nanjing Drum Tower Hospital, Nanjing, China.
Li X; The Affiliated Lianyungang Oriental Hospital of Xuzhou Medical University, Xuzhou, China.
Li B; Department of Clinical Laboratory, The People's Liberation Army Joint Service Support Unit 940 Hospital, Lanzhou, China.
Xin Y; Department of Clinical Laboratory, The People's Liberation Army Joint Service Support Unit 940 Hospital, Lanzhou, China.
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Źródło :
The Journal of international medical research [J Int Med Res] 2021 Nov; Vol. 49 (11), pp. 3000605211048293.
Typ publikacji :
Journal Article
MeSH Terms :
Diabetes Mellitus, Type 2*/genetics
Insulin Resistance*
Prediabetic State*
Animals ; Blood Glucose ; Carboxypeptidases ; DNA-Binding Proteins ; Fatty Acids, Nonesterified ; Humans ; Insulin ; Mice ; Phosphoproteins ; RNA-Binding Proteins ; Repressor Proteins ; Retrospective Studies
Czasopismo naukowe
Tytuł :
The association between triglyceride-glucose index and major adverse cardiovascular events in patients with acute coronary syndrome - dose-response meta-analysis.
Autorzy :
Akbar MR; Department of Cardiology and Vascular Medicine, Faculty of Medicine Universitas Padjadjaran, Rumah Sakit Umum Pusat Hasan Sadikin, Bandung, Indonesia. Electronic address: .
Pranata R; Department of Cardiology and Vascular Medicine, Faculty of Medicine Universitas Padjadjaran, Rumah Sakit Umum Pusat Hasan Sadikin, Bandung, Indonesia; Faculty of Medicine, Universitas Pelita Harapan, Tangerang, Indonesia. Electronic address: .
Wibowo A; Department of Cardiology and Vascular Medicine, Faculty of Medicine Universitas Padjadjaran, Rumah Sakit Umum Pusat Hasan Sadikin, Bandung, Indonesia. Electronic address: .
Irvan; Faculty of Medicine, Universitas Pelita Harapan, Tangerang, Indonesia. Electronic address: .
Sihite TA; Department of Cardiology and Vascular Medicine, Faculty of Medicine Universitas Padjadjaran, Rumah Sakit Umum Pusat Hasan Sadikin, Bandung, Indonesia. Electronic address: .
Martha JW; Department of Cardiology and Vascular Medicine, Faculty of Medicine Universitas Padjadjaran, Rumah Sakit Umum Pusat Hasan Sadikin, Bandung, Indonesia. Electronic address: .
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Źródło :
Nutrition, metabolism, and cardiovascular diseases : NMCD [Nutr Metab Cardiovasc Dis] 2021 Oct 28; Vol. 31 (11), pp. 3024-3030. Date of Electronic Publication: 2021 Aug 12.
Typ publikacji :
Journal Article; Meta-Analysis; Systematic Review
MeSH Terms :
Insulin Resistance*
Acute Coronary Syndrome/*blood
Blood Glucose/*metabolism
Diabetes Mellitus/*blood
Triglycerides/*blood
Acute Coronary Syndrome/diagnosis ; Acute Coronary Syndrome/mortality ; Acute Coronary Syndrome/therapy ; Biomarkers/blood ; Diabetes Mellitus/diagnosis ; Disease Progression ; Humans ; Myocardial Revascularization ; Predictive Value of Tests ; Prognosis ; Risk Assessment ; Risk Factors
Czasopismo naukowe

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