Temat: "Insulin-Like Growth Factor Binding Protein 5" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Pregnancy associated plasma protein-A2 (PAPP-A2) and stanniocalcin-2 (STC2) but not PAPP-A are associated with circulating total IGF-1 in a human adult population.
Autorzy:: Nimptsch K; Molecular Epidemiology Research Group, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Robert-Rössle-Straße 10, 13125, Berlin, Germany. .
Aydin EE; Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Chavarria RFR; Molecular Epidemiology Research Group, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Robert-Rössle-Straße 10, 13125, Berlin, Germany.
Janke J; Molecular Epidemiology Research Group, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Robert-Rössle-Straße 10, 13125, Berlin, Germany.; Biobank Technology Platform, Max-Delbrueck-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany.; Core Facility Biobank, Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Berlin, Germany.
Poy MN; John Hopkins University, All Children's Hospital, St. Petersburg, FL, USA.
Oxvig C; Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.
Steinbrecher A; Molecular Epidemiology Research Group, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Robert-Rössle-Straße 10, 13125, Berlin, Germany.
Pischon T; Molecular Epidemiology Research Group, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Robert-Rössle-Straße 10, 13125, Berlin, Germany.; Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; Biobank Technology Platform, Max-Delbrueck-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany.; Core Facility Biobank, Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Berlin, Germany.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Jan 20; Vol. 14 (1), pp. 1770. Date of Electronic Publication: 2024 Jan 20.
Typ publikacji:: Journal Article
MeSH Terms:: Insulin-Like Growth Factor I*/metabolism
Peptide Hormones*/metabolism
Piperazines*
Adult ; Humans ; Carrier Proteins ; Glycoproteins/metabolism ; Insulin-Like Growth Factor Binding Protein 1 ; Insulin-Like Growth Factor Binding Protein 2 ; Insulin-Like Growth Factor Binding Protein 3 ; Insulin-Like Growth Factor Binding Protein 5 ; Intercellular Signaling Peptides and Proteins/metabolism ; Pregnancy-Associated Plasma Protein-A/metabolism ; Young Adult ; Middle Aged ; Aged

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Tytuł:: The expression of IGFBP-5 in the reproductive axis and effect on the onset of puberty in female rats.
Autorzy:: Yao Z; Anhui Provincial Key Laboratory for Local Livestock and Poultry Genetic Resource Conservation and Bio-Breeding, 130 Changjiang West Road, Hefei, 230036, Anhui, China.; Department of Animal Veterinary Science, College of Animal Science and Technology, Anhui Agricultural University, 130 Changjiang West Road, Hefei, 230036, Anhui, China.
Lin M; Anhui Provincial Key Laboratory for Local Livestock and Poultry Genetic Resource Conservation and Bio-Breeding, 130 Changjiang West Road, Hefei, 230036, Anhui, China.; Department of Animal Veterinary Science, College of Animal Science and Technology, Anhui Agricultural University, 130 Changjiang West Road, Hefei, 230036, Anhui, China.
Lin T; Anhui Provincial Key Laboratory for Local Livestock and Poultry Genetic Resource Conservation and Bio-Breeding, 130 Changjiang West Road, Hefei, 230036, Anhui, China.; Department of Animal Veterinary Science, College of Animal Science and Technology, Anhui Agricultural University, 130 Changjiang West Road, Hefei, 230036, Anhui, China.
Gong X; Anhui Provincial Key Laboratory for Local Livestock and Poultry Genetic Resource Conservation and Bio-Breeding, 130 Changjiang West Road, Hefei, 230036, Anhui, China.; Department of Animal Veterinary Science, College of Animal Science and Technology, Anhui Agricultural University, 130 Changjiang West Road, Hefei, 230036, Anhui, China.
Qin P; Anhui Provincial Key Laboratory for Local Livestock and Poultry Genetic Resource Conservation and Bio-Breeding, 130 Changjiang West Road, Hefei, 230036, Anhui, China.; Department of Animal Veterinary Science, College of Animal Science and Technology, Anhui Agricultural University, 130 Changjiang West Road, Hefei, 230036, Anhui, China.
Li H; Anhui Provincial Key Laboratory for Local Livestock and Poultry Genetic Resource Conservation and Bio-Breeding, 130 Changjiang West Road, Hefei, 230036, Anhui, China.; Department of Animal Veterinary Science, College of Animal Science and Technology, Anhui Agricultural University, 130 Changjiang West Road, Hefei, 230036, Anhui, China.
Kang T; Anhui Provincial Key Laboratory for Local Livestock and Poultry Genetic Resource Conservation and Bio-Breeding, 130 Changjiang West Road, Hefei, 230036, Anhui, China.; Department of Animal Veterinary Science, College of Animal Science and Technology, Anhui Agricultural University, 130 Changjiang West Road, Hefei, 230036, Anhui, China.
Ye J; Anhui Provincial Key Laboratory for Local Livestock and Poultry Genetic Resource Conservation and Bio-Breeding, 130 Changjiang West Road, Hefei, 230036, Anhui, China.; Department of Animal Veterinary Science, College of Animal Science and Technology, Anhui Agricultural University, 130 Changjiang West Road, Hefei, 230036, Anhui, China.
Zhu Y; Department of Animal Veterinary Science, College of Animal Science and Technology, Anhui Agricultural University, 130 Changjiang West Road, Hefei, 230036, Anhui, China.
Hong Q; Department of Animal Veterinary Science, College of Animal Science and Technology, Anhui Agricultural University, 130 Changjiang West Road, Hefei, 230036, Anhui, China.
Liu Y; Anhui Provincial Key Laboratory for Local Livestock and Poultry Genetic Resource Conservation and Bio-Breeding, 130 Changjiang West Road, Hefei, 230036, Anhui, China.; Department of Animal Veterinary Science, College of Animal Science and Technology, Anhui Agricultural University, 130 Changjiang West Road, Hefei, 230036, Anhui, China.
Li Y; Anhui Provincial Key Laboratory for Local Livestock and Poultry Genetic Resource Conservation and Bio-Breeding, 130 Changjiang West Road, Hefei, 230036, Anhui, China.; Department of Animal Veterinary Science, College of Animal Science and Technology, Anhui Agricultural University, 130 Changjiang West Road, Hefei, 230036, Anhui, China.
Wang J; Anhui Provincial Key Laboratory for Local Livestock and Poultry Genetic Resource Conservation and Bio-Breeding, 130 Changjiang West Road, Hefei, 230036, Anhui, China.; Department of Animal Veterinary Science, College of Animal Science and Technology, Anhui Agricultural University, 130 Changjiang West Road, Hefei, 230036, Anhui, China.
Fang F; Anhui Provincial Key Laboratory for Local Livestock and Poultry Genetic Resource Conservation and Bio-Breeding, 130 Changjiang West Road, Hefei, 230036, Anhui, China. .; Department of Animal Veterinary Science, College of Animal Science and Technology, Anhui Agricultural University, 130 Changjiang West Road, Hefei, 230036, Anhui, China. .; Pokaż więcej
Źródło:: Reproductive biology and endocrinology : RB&E [Reprod Biol Endocrinol] 2022 Jul 12; Vol. 20 (1), pp. 100. Date of Electronic Publication: 2022 Jul 12.
Typ publikacji:: Journal Article
MeSH Terms:: Insulin-Like Growth Factor Binding Protein 5*/biosynthesis
Insulin-Like Growth Factor Binding Protein 5*/genetics
Puberty*/genetics
Puberty*/metabolism
Animals ; Female ; Gonadotropin-Releasing Hormone/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Rats

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Skocz do pozycji: 3.

Tytuł:: Protein Plasma Levels of the IGF Signalling System Are Altered in Major Depressive Disorder.
Autorzy:: Fernández-Pereira C; Translational Neuroscience Group, Galicia Sur Health Research Institute (IIS Galicia Sur), Área Sanitaria de Vigo-Hospital Álvaro Cunqueiro, SERGAS-UVIGO, CIBERSAM-ISCIII, 36213 Vigo, Spain.; Neuro Epigenetics Lab, Health Research Institute of Santiago de Compostela (IDIS), Santiago University Hospital Complex, 15706 Santiago de Compostela, Spain.; Rare Disease and Pediatric Medicine Group, Galicia Sur Health Research Institute (IIS Galicia Sur), SERGAS-UVIGO, 36312 Vigo, Spain.
Penedo MA; Translational Neuroscience Group, Galicia Sur Health Research Institute (IIS Galicia Sur), Área Sanitaria de Vigo-Hospital Álvaro Cunqueiro, SERGAS-UVIGO, CIBERSAM-ISCIII, 36213 Vigo, Spain.
Rivera-Baltanás T; Translational Neuroscience Group, Galicia Sur Health Research Institute (IIS Galicia Sur), Área Sanitaria de Vigo-Hospital Álvaro Cunqueiro, SERGAS-UVIGO, CIBERSAM-ISCIII, 36213 Vigo, Spain.
Pérez-Márquez T; Rare Disease and Pediatric Medicine Group, Galicia Sur Health Research Institute (IIS Galicia Sur), SERGAS-UVIGO, 36312 Vigo, Spain.
Alves-Villar M; Rare Disease and Pediatric Medicine Group, Galicia Sur Health Research Institute (IIS Galicia Sur), SERGAS-UVIGO, 36312 Vigo, Spain.
Fernández-Martínez R; Translational Neuroscience Group, Galicia Sur Health Research Institute (IIS Galicia Sur), Área Sanitaria de Vigo-Hospital Álvaro Cunqueiro, SERGAS-UVIGO, CIBERSAM-ISCIII, 36213 Vigo, Spain.
Veiga C; Cardiovascular Research Group, Galicia Sur Health Research Institute (IIS Galicia Sur), 36213 Vigo, Spain.
Salgado-Barreira Á; Department of Preventive Medicine and Public Health, Health Research Institute of Santiago de Compostela (IDIS), University of Santiago de Compostela, 15706 Santiago de Compostela, Spain.; Consortium for Biomedical Research in Epidemiology and Public Health (CIBER en Epidemiología y Salud Pública-CIBERESP, 28029 Madrid, Spain.
Prieto-González JM; Neuro Epigenetics Lab, Health Research Institute of Santiago de Compostela (IDIS), Santiago University Hospital Complex, 15706 Santiago de Compostela, Spain.; Translational Research in Neurological Diseases Group, Health Research Institute of Santiago de Compostela (IDIS), Santiago University Hospital Complex, SERGAS-USC, 15706 Santiago de Compostela, Spain.; Neurology Service, Santiago University Hospital Complex, 15706 Santiago de Compostela, Spain.
Ortolano S; Rare Disease and Pediatric Medicine Group, Galicia Sur Health Research Institute (IIS Galicia Sur), SERGAS-UVIGO, 36312 Vigo, Spain.
Olivares JM; Translational Neuroscience Group, Galicia Sur Health Research Institute (IIS Galicia Sur), Área Sanitaria de Vigo-Hospital Álvaro Cunqueiro, SERGAS-UVIGO, CIBERSAM-ISCIII, 36213 Vigo, Spain.
Agís-Balboa RC; Neuro Epigenetics Lab, Health Research Institute of Santiago de Compostela (IDIS), Santiago University Hospital Complex, 15706 Santiago de Compostela, Spain.; Translational Research in Neurological Diseases Group, Health Research Institute of Santiago de Compostela (IDIS), Santiago University Hospital Complex, SERGAS-USC, 15706 Santiago de Compostela, Spain.; Neurology Service, Santiago University Hospital Complex, 15706 Santiago de Compostela, Spain.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Oct 17; Vol. 24 (20). Date of Electronic Publication: 2023 Oct 17.
Typ publikacji:: Journal Article
MeSH Terms:: Insulin-Like Growth Factor II*/metabolism
Depressive Disorder, Major*/drug therapy
Humans ; Rats ; Animals ; Mice ; Insulin-Like Growth Factor Binding Protein 3 ; Insulin-Like Growth Factor Binding Protein 5 ; Insulin-Like Growth Factor I/metabolism ; Anhedonia ; Antidepressive Agents/pharmacology ; Antidepressive Agents/therapeutic use ; Insulin-Like Growth Factor Binding Protein 2

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Skocz do pozycji: 4.

Tytuł:: Insulin-like growth factor 5 associates with human Aß plaques and promotes cognitive impairment.
Autorzy:: Rauskolb S; Institute of Clinical Neurobiology, University of Würzburg, Versbacher-Str. 5, 97078, Würzburg, Germany.
Andreska T; Institute of Clinical Neurobiology, University of Würzburg, Versbacher-Str. 5, 97078, Würzburg, Germany.
Fries S; Institute of Clinical Neurobiology, University of Würzburg, Versbacher-Str. 5, 97078, Würzburg, Germany.
von Collenberg CR; Institute of Clinical Neurobiology, University of Würzburg, Versbacher-Str. 5, 97078, Würzburg, Germany.
Blum R; Institute of Clinical Neurobiology, University of Würzburg, Versbacher-Str. 5, 97078, Würzburg, Germany.; Department of Neurology, University Hospital Würzburg, Josef-Schneider-Str. 11, 97080, Würzburg, Germany.
Monoranu CM; Department of Neuropathology, Institute of Pathology, University of Würzburg, Josef-Schneider-Str. 2, 97080, Würzburg, Germany.
Villmann C; Institute of Clinical Neurobiology, University of Würzburg, Versbacher-Str. 5, 97078, Würzburg, Germany.
Sendtner M; Institute of Clinical Neurobiology, University of Würzburg, Versbacher-Str. 5, 97078, Würzburg, Germany. Sendtner_.; Pokaż więcej
Źródło:: Acta neuropathologica communications [Acta Neuropathol Commun] 2022 May 05; Vol. 10 (1), pp. 68. Date of Electronic Publication: 2022 May 05.
Typ publikacji:: Journal Article
MeSH Terms:: Alzheimer Disease*/pathology
Cognitive Dysfunction*/pathology
Insulin-Like Growth Factor Binding Protein 5*
Animals ; Humans ; Mice ; Mice, Transgenic ; Neurons/metabolism ; Plaque, Amyloid/pathology

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Skocz do pozycji: 5.

Tytuł:: Time-Dependent Changes in Muscle IGF1-IGFBP5-PAPP System after Sciatic Denervation.
Autorzy:: Martín AI; Departamento de Fisiología, Facultad de Medicina, Universidad Complutense de Madrid, Plaza de Ramón y Cajal sn, 28040 Madrid, Spain.
Moreno-Rupérez Á; Departamento de Fisiología, Facultad de Medicina, Universidad Complutense de Madrid, Plaza de Ramón y Cajal sn, 28040 Madrid, Spain.
Nebot E; Departamento de Fisiología, Facultad de Medicina, Universidad Complutense de Madrid, Plaza de Ramón y Cajal sn, 28040 Madrid, Spain.
Granado M; Departamento de Fisiología, Facultad de Medicina, Universidad Autónoma de Madrid, Calle Arzobispo Morcillo 2, 28029 Madrid, Spain.
Jaque D; Nanomaterials for Bioimaging Group (NanoBIG), Departamento de Física de Materiales, Facultad de Ciencias, Universidad Autónoma de Madrid, Avenida Francisco Tomas y Valiente, 28049 Madrid, Spain.
Nieto-Bona MP; Departamento de Ciencias Básicas de la Salud, Facultad CC Salud, Universidad Rey Juan Carlos, Avenida de Atenas sn, 20922 Madrid, Spain.
López-Calderón A; Departamento de Fisiología, Facultad de Medicina, Universidad Complutense de Madrid, Plaza de Ramón y Cajal sn, 28040 Madrid, Spain.
Priego T; Departamento de Fisiología, Facultad de Enfermería, Fisioterapia y Podología, Universidad Complutense de Madrid, Plaza de Ramón y Cajal sn, 28040 Madrid, Spain.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Sep 14; Vol. 24 (18). Date of Electronic Publication: 2023 Sep 14.
Typ publikacji:: Journal Article
MeSH Terms:: Insulin-Like Growth Factor I*/metabolism
Pregnancy-Associated Plasma Protein-A*/metabolism
Insulin-Like Growth Factor Binding Protein 5/genetics ; Peptide Hydrolases/metabolism ; Muscles/metabolism ; Denervation

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Skocz do pozycji: 6.

Tytuł:: Single cell RNA sequencing identifies IGFBP5 and QKI as ciliated epithelial cell genes associated with severe COPD.
Autorzy:: Li X; Department of Medicine, University of Pittsburgh, NW628 UPMC Montefiore, 3459 Fifth Avenue, Pittsburgh, PA, 15213, USA.; VA Pittsburgh Healthcare System, Pittsburgh, PA, USA.
Noell G; Centro Investigación Biomedica en Red (CIBERES), Institut D'investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.
Tabib T; Department of Medicine, University of Pittsburgh, NW628 UPMC Montefiore, 3459 Fifth Avenue, Pittsburgh, PA, 15213, USA.
Gregory AD; Department of Medicine, University of Pittsburgh, NW628 UPMC Montefiore, 3459 Fifth Avenue, Pittsburgh, PA, 15213, USA.
Trejo Bittar HE; Department of Pathology, University of Pittsburgh, Pittsburgh, PA, USA.
Vats R; Vascular Medicine Institute, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Kaminski TW; Vascular Medicine Institute, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Sembrat J; Department of Medicine, University of Pittsburgh, NW628 UPMC Montefiore, 3459 Fifth Avenue, Pittsburgh, PA, 15213, USA.
Snyder ME; Department of Medicine, University of Pittsburgh, NW628 UPMC Montefiore, 3459 Fifth Avenue, Pittsburgh, PA, 15213, USA.
Chandra D; Department of Medicine, University of Pittsburgh, NW628 UPMC Montefiore, 3459 Fifth Avenue, Pittsburgh, PA, 15213, USA.
Chen K; Department of Medicine, University of Pittsburgh, NW628 UPMC Montefiore, 3459 Fifth Avenue, Pittsburgh, PA, 15213, USA.
Zou C; Department of Medicine, University of Pittsburgh, NW628 UPMC Montefiore, 3459 Fifth Avenue, Pittsburgh, PA, 15213, USA.; VA Pittsburgh Healthcare System, Pittsburgh, PA, USA.
Zhang Y; Department of Medicine, University of Pittsburgh, NW628 UPMC Montefiore, 3459 Fifth Avenue, Pittsburgh, PA, 15213, USA.
Sundd P; Vascular Medicine Institute, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
McDyer JF; Department of Medicine, University of Pittsburgh, NW628 UPMC Montefiore, 3459 Fifth Avenue, Pittsburgh, PA, 15213, USA.
Sciurba F; Department of Medicine, University of Pittsburgh, NW628 UPMC Montefiore, 3459 Fifth Avenue, Pittsburgh, PA, 15213, USA.
Rojas M; Department of Medicine, University of Pittsburgh, NW628 UPMC Montefiore, 3459 Fifth Avenue, Pittsburgh, PA, 15213, USA.
Lafyatis R; Department of Medicine, University of Pittsburgh, NW628 UPMC Montefiore, 3459 Fifth Avenue, Pittsburgh, PA, 15213, USA.
Shapiro SD; Department of Medicine, University of Pittsburgh, NW628 UPMC Montefiore, 3459 Fifth Avenue, Pittsburgh, PA, 15213, USA.
Faner R; Centro Investigación Biomedica en Red (CIBERES), Institut D'investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.
Nyunoya T; Department of Medicine, University of Pittsburgh, NW628 UPMC Montefiore, 3459 Fifth Avenue, Pittsburgh, PA, 15213, USA. .; VA Pittsburgh Healthcare System, Pittsburgh, PA, USA. .; Pokaż więcej
Źródło:: Respiratory research [Respir Res] 2021 Apr 06; Vol. 22 (1), pp. 100. Date of Electronic Publication: 2021 Apr 06.
Typ publikacji:: Journal Article
MeSH Terms:: Insulin-Like Growth Factor Binding Protein 5/*genetics
Lung/*metabolism
Pulmonary Disease, Chronic Obstructive/*genetics
RNA/*genetics
RNA-Binding Proteins/*genetics
Sequence Analysis, RNA/*methods
Transcriptome/*genetics
Adult ; Aged ; Epithelial Cells/metabolism ; Epithelial Cells/pathology ; Female ; Gene Expression Profiling/methods ; Humans ; Insulin-Like Growth Factor Binding Protein 5/biosynthesis ; Lung/pathology ; Male ; Middle Aged ; Pulmonary Disease, Chronic Obstructive/metabolism ; Pulmonary Disease, Chronic Obstructive/pathology ; RNA/metabolism ; RNA-Binding Proteins/biosynthesis ; Severity of Illness Index ; Young Adult

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Skocz do pozycji: 7.

Tytuł:: Significant association of serum autoantibodies to TYMS, HAPLN1 and IGFBP5 with early stage canine malignant mammary tumours.
Autorzy:: Chang SC; Department of Veterinary Medicine, College of Veterinary Medicine, National Chung Hsing University, Taichung, Taiwan.
Yuan SH; Department of Veterinary Medicine, College of Veterinary Medicine, National Chung Hsing University, Taichung, Taiwan.
Li CY; Department of Veterinary Medicine, College of Veterinary Medicine, National Chung Hsing University, Taichung, Taiwan.
Chang HM; Department of Veterinary Medicine, College of Veterinary Medicine, National Chung Hsing University, Taichung, Taiwan.
Wang HC; Department of Veterinary Medicine, College of Veterinary Medicine, National Chung Hsing University, Taichung, Taiwan.
Pan YA; Department of Veterinary Medicine, College of Veterinary Medicine, National Chung Hsing University, Taichung, Taiwan.
Hsueh PC; Department of Medical Biotechnology and Laboratory Science, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Wu CC; Department of Medical Biotechnology and Laboratory Science, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Yang Y; Division of Hematology-Oncology, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.
Liu HP; Department of Veterinary Medicine, College of Veterinary Medicine, National Chung Hsing University, Taichung, Taiwan.; Pokaż więcej
Źródło:: Veterinary and comparative oncology [Vet Comp Oncol] 2021 Mar; Vol. 19 (1), pp. 172-182. Date of Electronic Publication: 2020 Oct 19.
Typ publikacji:: Journal Article
MeSH Terms:: Dog Diseases/*immunology
Extracellular Matrix Proteins/*metabolism
Insulin-Like Growth Factor Binding Protein 5/*metabolism
Mammary Neoplasms, Animal/*immunology
Proteoglycans/*metabolism
Thymidylate Synthase/*metabolism
Animals ; Autoantibodies/blood ; Biomarkers, Tumor ; Carcinoma/metabolism ; Carcinoma/veterinary ; Dog Diseases/blood ; Dogs ; Extracellular Matrix Proteins/genetics ; Female ; Gene Expression Regulation, Neoplastic ; Insulin-Like Growth Factor Binding Protein 5/genetics ; Mammary Neoplasms, Animal/metabolism ; Neoplasm Staging/veterinary ; Proteoglycans/genetics ; Thymidylate Synthase/genetics

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Skocz do pozycji: 8.

Tytuł:: Phenotypic Characterization of Transgenic Mice Expressing Human IGFBP-5.
Autorzy:: Nguyen XX; Division of Rheumatology & Immunology, Department of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.
Sanderson M; Division of Rheumatology & Immunology, Department of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.
Helke K; Departments of Comparative Medicine and Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.
Feghali-Bostwick C; Division of Rheumatology & Immunology, Department of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2020 Dec 30; Vol. 22 (1). Date of Electronic Publication: 2020 Dec 30.
Typ publikacji:: Journal Article
MeSH Terms:: Extracellular Matrix/*metabolism
Fibroblasts/*cytology
Fibrosis/*pathology
Insulin-Like Growth Factor Binding Protein 5/*metabolism
Lung/*cytology
Skin/*cytology
Animals ; Antibiotics, Antineoplastic/toxicity ; Bleomycin/toxicity ; Cells, Cultured ; Female ; Fibroblasts/metabolism ; Fibrosis/chemically induced ; Fibrosis/metabolism ; Humans ; Insulin-Like Growth Factor Binding Protein 5/genetics ; Lung/metabolism ; Male ; Mice ; Mice, Transgenic ; Phenotype ; Skin/metabolism

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Skocz do pozycji: 9.

Tytuł:: Insulin-Like Growth Factor Binding Protein 5-A Probable Target of Kidney Renal Papillary Renal Cell Carcinoma.
Autorzy:: Wang S; Department of Nephrology, Chinese PLA General Hospital, Chinese PLA Institute of Nephrology, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Diseases, China.
Hong Q; Department of Nephrology, Chinese PLA General Hospital, Chinese PLA Institute of Nephrology, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Diseases, China.
Geng X; Department of Nephrology, Chinese PLA General Hospital, Chinese PLA Institute of Nephrology, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Diseases, China.
Chi K; Department of Nephrology, Chinese PLA General Hospital, Chinese PLA Institute of Nephrology, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Diseases, China.
Cai G; Department of Nephrology, Chinese PLA General Hospital, Chinese PLA Institute of Nephrology, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Diseases, China.
Wu D; Department of Nephrology, Chinese PLA General Hospital, Chinese PLA Institute of Nephrology, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Diseases, China.; Pokaż więcej
Źródło:: BioMed research international [Biomed Res Int] 2019 Nov 11; Vol. 2019, pp. 3210324. Date of Electronic Publication: 2019 Nov 11 (Print Publication: 2019).
Typ publikacji:: Journal Article
MeSH Terms:: Databases, Genetic*
Gene Expression Regulation, Neoplastic*
Carcinoma, Renal Cell/*metabolism
Insulin-Like Growth Factor Binding Protein 5/*biosynthesis
Kidney Neoplasms/*metabolism
Neoplasm Proteins/*biosynthesis
Carcinoma, Renal Cell/genetics ; Carcinoma, Renal Cell/mortality ; Carcinoma, Renal Cell/pathology ; Cell Line, Tumor ; Disease-Free Survival ; Humans ; Insulin-Like Growth Factor Binding Protein 5/genetics ; Kidney Neoplasms/genetics ; Kidney Neoplasms/pathology ; Neoplasm Proteins/genetics ; Survival Rate ; Transforming Growth Factor beta/genetics ; Transforming Growth Factor beta/metabolism ; Vascular Endothelial Growth Factor A/genetics ; Vascular Endothelial Growth Factor A/metabolism

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Skocz do pozycji: 10.

Tytuł:: A common variant of the pregnancy-associated plasma protein-A (PAPPA) gene encodes a protein with reduced proteolytic activity towards IGF-binding proteins.
Autorzy:: Bøtkjær JA; Laboratory of Reproductive Biology, The Juliane Marie Centre for Women, Children and Reproduction, Rigshospitalet, Copenhagen University Hospital, Copenhagen University, Copenhagen, DK-2100, Denmark. .
Noer PR; Department of Molecular Biology and Genetics, University of Aarhus, Aarhus, DK-8000, Denmark.
Oxvig C; Department of Molecular Biology and Genetics, University of Aarhus, Aarhus, DK-8000, Denmark.
Yding Andersen C; Laboratory of Reproductive Biology, The Juliane Marie Centre for Women, Children and Reproduction, Rigshospitalet, Copenhagen University Hospital, Copenhagen University, Copenhagen, DK-2100, Denmark.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2019 Sep 13; Vol. 9 (1), pp. 13231. Date of Electronic Publication: 2019 Sep 13.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Polymorphism, Single Nucleotide*
Glycoproteins/*metabolism
Insulin-Like Growth Factor Binding Protein 3/*metabolism
Insulin-Like Growth Factor Binding Protein 4/*metabolism
Insulin-Like Growth Factor Binding Protein 5/*metabolism
Intercellular Signaling Peptides and Proteins/*metabolism
Pregnancy-Associated Plasma Protein-A/*genetics
Female ; Glycoproteins/genetics ; HEK293 Cells ; Humans ; Insulin-Like Growth Factor Binding Protein 3/genetics ; Insulin-Like Growth Factor Binding Protein 4/genetics ; Insulin-Like Growth Factor Binding Protein 5/genetics ; Intercellular Signaling Peptides and Proteins/genetics ; Pregnancy ; Pregnancy-Associated Plasma Protein-A/metabolism ; Protein Binding ; Proteolysis

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Skocz do pozycji: 11.

Tytuł:: Identification of Impacted Pathways and Transcriptomic Markers as Potential Mediators of Pulmonary Fibrosis in Transgenic Mice Expressing Human IGFBP5.
Autorzy:: Nguyen XX; Division of Rheumatology & Immunology, Department of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.
Renaud L; Division of Rheumatology & Immunology, Department of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.
Feghali-Bostwick C; Division of Rheumatology & Immunology, Department of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Nov 22; Vol. 22 (22). Date of Electronic Publication: 2021 Nov 22.
Typ publikacji:: Journal Article
MeSH Terms:: Insulin-Like Growth Factor Binding Protein 5/*genetics
Pulmonary Fibrosis/*genetics
Transcriptome/*genetics
Animals ; Biomarkers/metabolism ; Calcium Signaling/genetics ; Extracellular Matrix/genetics ; Fibroblasts/metabolism ; Humans ; Lung/metabolism ; Lung/pathology ; Mice ; Mice, Transgenic ; Pulmonary Fibrosis/pathology ; RNA-Seq

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Skocz do pozycji: 12.

Tytuł:: MiR-137 inhibited cell proliferation and migration of vascular smooth muscle cells via targeting IGFBP-5 and modulating the mTOR/STAT3 signaling.
Autorzy:: Pan J; Clinical Medical College, Xi'an Medical University, Xi'an City, Shaanxi Province, China.
Li K; Department of Cardiology, the First Affiliated Hospital of Xi'an Medical University, Xi'an City, Shaanxi Province, China.
Huang W; Clinical Medical College, Xi'an Medical University, Xi'an City, Shaanxi Province, China.
Zhang X; Clinical Medical College, Xi'an Medical University, Xi'an City, Shaanxi Province, China.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2017 Oct 10; Vol. 12 (10), pp. e0186245. Date of Electronic Publication: 2017 Oct 10 (Print Publication: 2017).
Typ publikacji:: Journal Article
MeSH Terms:: Signal Transduction*
Insulin-Like Growth Factor Binding Protein 5/*genetics
MicroRNAs/*genetics
Myocytes, Smooth Muscle/*metabolism
STAT3 Transcription Factor/*genetics
TOR Serine-Threonine Kinases/*genetics
Aorta/cytology ; Aorta/drug effects ; Aorta/metabolism ; Base Sequence ; Becaplermin ; Binding Sites ; Cell Line ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Computational Biology ; Diffusion Chambers, Culture ; Gene Expression Regulation ; Genes, Reporter ; Humans ; Insulin-Like Growth Factor Binding Protein 5/metabolism ; Luciferases/genetics ; Luciferases/metabolism ; MicroRNAs/metabolism ; Myocytes, Smooth Muscle/cytology ; Myocytes, Smooth Muscle/drug effects ; Proto-Oncogene Proteins c-sis/pharmacology ; STAT3 Transcription Factor/metabolism ; TOR Serine-Threonine Kinases/metabolism

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Skocz do pozycji: 13.

Tytuł:: IGF1R activation and the in vitro antiproliferative efficacy of IGF1R inhibitor are inversely correlated with IGFBP5 expression in bladder cancer.
Autorzy:: Neuzillet Y; Hôpital Foch, Département d'Urologie, 40 Rue Worth, 92151, Suresnes, France.; Université de Versailles - Saint-Quentin-en-Yvelines, 78000, Versailles, France.; Institut Curie, PSL Research University, CNRS, UMR144, Equipe Labellisée Ligue contre le Cancer, 75005, Paris, France.; Sorbonne Universités, UPMC Université Paris 06, CNRS, UMR144, 75005, Paris, France.
Chapeaublanc E; Institut Curie, PSL Research University, CNRS, UMR144, Equipe Labellisée Ligue contre le Cancer, 75005, Paris, France.; Sorbonne Universités, UPMC Université Paris 06, CNRS, UMR144, 75005, Paris, France.
Krucker C; Institut Curie, PSL Research University, CNRS, UMR144, Equipe Labellisée Ligue contre le Cancer, 75005, Paris, France.; Sorbonne Universités, UPMC Université Paris 06, CNRS, UMR144, 75005, Paris, France.
De Koning L; Institut Curie, PSL Research University, CNRS, UMR144, Equipe Labellisée Ligue contre le Cancer, 75005, Paris, France.; Département de Recherche Translationnelle, Cedex 05, 75248, Paris, France.
Lebret T; Hôpital Foch, Département d'Urologie, 40 Rue Worth, 92151, Suresnes, France.; Université de Versailles - Saint-Quentin-en-Yvelines, 78000, Versailles, France.
Radvanyi F; Institut Curie, PSL Research University, CNRS, UMR144, Equipe Labellisée Ligue contre le Cancer, 75005, Paris, France.; Sorbonne Universités, UPMC Université Paris 06, CNRS, UMR144, 75005, Paris, France.
Bernard-Pierrot I; Institut Curie, PSL Research University, CNRS, UMR144, Equipe Labellisée Ligue contre le Cancer, 75005, Paris, France. .; Sorbonne Universités, UPMC Université Paris 06, CNRS, UMR144, 75005, Paris, France. .; UMR 144 CNRS/IC, Institut Curie, 26 rue d'Ulm, CEDEX 05, 75248, Paris, France. .; Pokaż więcej
Źródło:: BMC cancer [BMC Cancer] 2017 Sep 07; Vol. 17 (1), pp. 636. Date of Electronic Publication: 2017 Sep 07.
Typ publikacji:: Journal Article
MeSH Terms:: Gene Expression Regulation, Neoplastic*
Insulin-Like Growth Factor Binding Protein 5/*genetics
Receptor, IGF Type 1/*agonists
Receptor, IGF Type 1/*antagonists & inhibitors
Urinary Bladder Neoplasms/*genetics
Urinary Bladder Neoplasms/*metabolism
Aged ; Aged, 80 and over ; Carrier Proteins ; Cell Line, Tumor ; Cell Proliferation ; Female ; Humans ; Insulin-Like Growth Factor Binding Protein 5/metabolism ; Ligands ; Male ; Middle Aged ; Neoplasm Grading ; Neoplasm Staging ; Protein Binding ; RNA, Messenger/genetics ; Signal Transduction ; Urinary Bladder Neoplasms/pathology

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Skocz do pozycji: 14.

Tytuł:: microRNA -140-5p inhibits colorectal cancer invasion and metastasis by targeting ADAMTS5 and IGFBP5.
Autorzy:: Yu L; Department of Pathology, Dalian Medical University, Dalian, 116044, People's Republic of China.
Lu Y; Department of Pathology, Dalian Medical University, Dalian, 116044, People's Republic of China.; Teaching Laboratory of Morphology, Dalian Medical University, No. 9 West Section, Lvshun South Road, Dalian, 116044, People's Republic of China.
Han X; Department of Pathology, Dalian Medical University, Dalian, 116044, People's Republic of China.
Zhao W; Department of Pathology, Dalian Medical University, Dalian, 116044, People's Republic of China.
Li J; Department of Pathology, Dalian Medical University, Dalian, 116044, People's Republic of China.
Mao J; Department of Pathology, Dalian Medical University, Dalian, 116044, People's Republic of China.; Key Laboratory of Tumor Stem Cell Research of Liaoning Province, Dalian Medical University, Dalian, 116044, People's Republic of China.
Wang B; Department of Pathology, Dalian Medical University, Dalian, 116044, People's Republic of China.
Shen J; Teaching Laboratory of Morphology, Dalian Medical University, No. 9 West Section, Lvshun South Road, Dalian, 116044, People's Republic of China.
Fan S; Department of Pathology, Dalian Medical University, Dalian, 116044, People's Republic of China.
Wang L; Department of Pathology, Dalian Medical University, Dalian, 116044, People's Republic of China.
Wang M; Department of Pathology, Dalian Medical University, Dalian, 116044, People's Republic of China.; Key Laboratory of Tumor Metastasis Research of Liaoning Province, Dalian Medical University, Dalian, 116044, People's Republic of China.
Li L; Department of Pathology, Dalian Medical University, Dalian, 116044, People's Republic of China.; Key Laboratory of Tumor Stem Cell Research of Liaoning Province, Dalian Medical University, Dalian, 116044, People's Republic of China.
Tang J; Department of Pathology, Dalian Medical University, Dalian, 116044, People's Republic of China.; Key Laboratory of Tumor Metastasis Research of Liaoning Province, Dalian Medical University, Dalian, 116044, People's Republic of China.
Song B; Department of Pathology, Dalian Medical University, Dalian, 116044, People's Republic of China. .; Teaching Laboratory of Morphology, Dalian Medical University, No. 9 West Section, Lvshun South Road, Dalian, 116044, People's Republic of China. .; Pokaż więcej
Źródło:: Stem cell research & therapy [Stem Cell Res Ther] 2016 Dec 01; Vol. 7 (1), pp. 180. Date of Electronic Publication: 2016 Dec 01.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Retracted Publication
MeSH Terms:: Gene Expression Regulation, Neoplastic*
ADAMTS5 Protein/*genetics
Colorectal Neoplasms/*genetics
Insulin-Like Growth Factor Binding Protein 5/*genetics
MicroRNAs/*genetics
ADAMTS5 Protein/antagonists & inhibitors ; ADAMTS5 Protein/metabolism ; Aged ; Cell Line, Tumor ; Cell Movement ; Colorectal Neoplasms/metabolism ; Colorectal Neoplasms/pathology ; Disease Progression ; Female ; HCT116 Cells ; Humans ; Insulin-Like Growth Factor Binding Protein 5/antagonists & inhibitors ; Insulin-Like Growth Factor Binding Protein 5/metabolism ; Male ; MicroRNAs/antagonists & inhibitors ; MicroRNAs/metabolism ; Middle Aged ; Neoplasm Invasiveness ; Neoplasm Metastasis ; Neoplasm Staging ; Oligoribonucleotides, Antisense/genetics ; Oligoribonucleotides, Antisense/metabolism ; RNA, Small Interfering/genetics ; RNA, Small Interfering/metabolism ; Signal Transduction

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Skocz do pozycji: 15.

Tytuł:: The C-terminus of IGFBP-5 suppresses tumor growth by inhibiting angiogenesis.
Autorzy:: Hwang JR; Samsung Biomedical Research Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 06351, Korea.
Cho YJ; Department of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 06351, Korea.; Institute for Refractory Cancer Research, Samsung Medical Center, Seoul, Korea.
Lee Y; Samsung Biomedical Research Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 06351, Korea.
Park Y; Samsung Biomedical Research Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 06351, Korea.
Han HD; Department of Immunology, School of Medicine, Konkuk University, Chungju 27478, Korea.
Ahn HJ; Center for Theragnosis, Biomedical Research Institute, Korea Institute of Science and Technology, Seongbuk-Gu, Seoul 02792, Korea.
Lee JH; Cancer Center, Cha Bundang Hospital, Seongnam-si, Gyeonggi-do 13496, Korea.
Lee JW; Department of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 06351, Korea.; Institute for Refractory Cancer Research, Samsung Medical Center, Seoul, Korea.; Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, Seoul, Korea.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2016 Dec 23; Vol. 6, pp. 39334. Date of Electronic Publication: 2016 Dec 23.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Neovascularization, Pathologic*
Insulin-Like Growth Factor Binding Protein 5/*metabolism
Ovarian Neoplasms/*pathology
Animals ; DNA Mutational Analysis ; Disease Models, Animal ; Female ; Heterografts ; Humans ; Insulin-Like Growth Factor Binding Protein 5/genetics ; Mice ; Neoplasm Transplantation ; Sequence Deletion ; Signal Transduction

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Skocz do pozycji: 16.

Tytuł:: Analysis of 17β-estradiol (E2) role in the regulation of corpus luteum function in pregnant rats: Involvement of IGFBP5 in the E2-mediated actions.
Autorzy:: Tripathy S; Department of Molecular Reproduction, Development and Genetics, Indian Institute of Science, Bangalore, 560012, India.
Asaithambi K; Department of Molecular Reproduction, Development and Genetics, Indian Institute of Science, Bangalore, 560012, India.
Jayaram P; Department of Molecular Reproduction, Development and Genetics, Indian Institute of Science, Bangalore, 560012, India.
Medhamurthy R; Department of Molecular Reproduction, Development and Genetics, Indian Institute of Science, Bangalore, 560012, India. .; Pokaż więcej
Źródło:: Reproductive biology and endocrinology : RB&E [Reprod Biol Endocrinol] 2016 Apr 12; Vol. 14, pp. 19. Date of Electronic Publication: 2016 Apr 12.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Corpus Luteum/*metabolism
Estradiol/*physiology
Insulin-Like Growth Factor Binding Protein 5/*physiology
Anastrozole ; Androgen Antagonists/pharmacology ; Animals ; Aromatase Inhibitors/pharmacology ; Cell Proliferation ; Female ; Flutamide/pharmacology ; Gene Expression/drug effects ; Gene Expression Profiling ; Insulin-Like Growth Factor Binding Protein 5/metabolism ; Nitriles/pharmacology ; Oligonucleotide Array Sequence Analysis ; Pregnancy ; Rats ; Triazoles/pharmacology

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Skocz do pozycji: 17.

Tytuł:: Age-related changes in miR-143-3p:Igfbp5 interactions affect muscle regeneration.
Autorzy:: Soriano-Arroquia A; Institute of Ageing and Chronic Disease, University of Liverpool, 6 West Derby Street, Liverpool, L7 8TX, UK.
McCormick R; Institute of Ageing and Chronic Disease, University of Liverpool, 6 West Derby Street, Liverpool, L7 8TX, UK.
Molloy AP; University Hospital Aintree, Liverpool, UK.
McArdle A; Institute of Ageing and Chronic Disease, University of Liverpool, 6 West Derby Street, Liverpool, L7 8TX, UK.
Goljanek-Whysall K; Institute of Ageing and Chronic Disease, University of Liverpool, 6 West Derby Street, Liverpool, L7 8TX, UK.; Pokaż więcej
Źródło:: Aging cell [Aging Cell] 2016 Apr; Vol. 15 (2), pp. 361-9. Date of Electronic Publication: 2016 Jan 13.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Aging/*physiology
Insulin-Like Growth Factor Binding Protein 5/*genetics
MicroRNAs/*genetics
Muscle, Skeletal/*physiology
Regeneration/*physiology
Adult ; Aged ; Aging/metabolism ; Aging/pathology ; Animals ; Carrier Proteins/genetics ; Carrier Proteins/metabolism ; Cellular Senescence/physiology ; Female ; Humans ; Insulin-Like Growth Factor Binding Protein 5/metabolism ; Mice ; Mice, Inbred C57BL ; MicroRNAs/biosynthesis ; Muscle, Skeletal/metabolism ; Myoblasts, Skeletal/cytology ; Myoblasts, Skeletal/metabolism ; Regeneration/genetics ; Satellite Cells, Skeletal Muscle/cytology ; Satellite Cells, Skeletal Muscle/metabolism

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Skocz do pozycji: 18.

Tytuł:: IGFBP-5 Promotes Fibrosis Independently of Its Translocation to the Nucleus and Its Interaction with Nucleolin and IGF.
Autorzy:: Su Y; Department of Medicine, Division of Rheumatology & Immunology, Medical University of South Carolina, Charleston, South Carolina, United States of America.
Nishimoto T; Department of Medicine, Division of Rheumatology & Immunology, Medical University of South Carolina, Charleston, South Carolina, United States of America.
Feghali-Bostwick C; Department of Medicine, Division of Rheumatology & Immunology, Medical University of South Carolina, Charleston, South Carolina, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2015 Jun 23; Vol. 10 (6), pp. e0130546. Date of Electronic Publication: 2015 Jun 23 (Print Publication: 2015).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Cell Nucleus/*metabolism
Insulin-Like Growth Factor Binding Protein 5/*physiology
Phosphoproteins/*metabolism
RNA-Binding Proteins/*metabolism
Somatomedins/*metabolism
Fibrosis ; Humans ; Insulin-Like Growth Factor Binding Protein 5/genetics ; Protein Transport ; Nucleolin

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Skocz do pozycji: 19.

Tytuł:: IRE1α and IGF signaling predict resistance to an endoplasmic reticulum stress-inducing drug in glioblastoma cells.
Autorzy:: Rodvold JJ; The Laboratory of Immunology, Department of Medicine and Moores Cancer Center, University of California, San Diego 9500 Gilman Drive, La Jolla, CA, 92093-0815, USA.
Xian S; Division of Medical Genetics, Department of Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA.
Nussbacher J; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, California, USA.
Tsui B; Division of Medical Genetics, Department of Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA.
Cameron Waller T; Division of Medical Genetics, Department of Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA.
Searles SC; The Laboratory of Immunology, Department of Medicine and Moores Cancer Center, University of California, San Diego 9500 Gilman Drive, La Jolla, CA, 92093-0815, USA.
Lew A; The Laboratory of Immunology, Department of Medicine and Moores Cancer Center, University of California, San Diego 9500 Gilman Drive, La Jolla, CA, 92093-0815, USA.
Jiang P; Department of Translational Neurosciences and Neurotherapeutics, John Wayne Cancer Institute/Pacific Neuroscience Institute, 2200 Santa Monica Boulevard, Santa Monica, CA, 90404, USA.
Babic I; Department of Translational Neurosciences and Neurotherapeutics, John Wayne Cancer Institute/Pacific Neuroscience Institute, 2200 Santa Monica Boulevard, Santa Monica, CA, 90404, USA.
Nomura N; Department of Translational Neurosciences and Neurotherapeutics, John Wayne Cancer Institute/Pacific Neuroscience Institute, 2200 Santa Monica Boulevard, Santa Monica, CA, 90404, USA.
Lin JH; Department of Pathology, Stanford University, Palo Alto, CA, 94305, USA.
Kesari S; Department of Translational Neurosciences and Neurotherapeutics, John Wayne Cancer Institute/Pacific Neuroscience Institute, 2200 Santa Monica Boulevard, Santa Monica, CA, 90404, USA. .
Carter H; Division of Medical Genetics, Department of Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA. .
Zanetti M; The Laboratory of Immunology, Department of Medicine and Moores Cancer Center, University of California, San Diego 9500 Gilman Drive, La Jolla, CA, 92093-0815, USA. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2020 May 20; Vol. 10 (1), pp. 8348. Date of Electronic Publication: 2020 May 20.
Typ publikacji:: Journal Article; Observational Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Brain Neoplasms/*drug therapy
Endoribonucleases/*metabolism
Glioblastoma/*drug therapy
Protein Serine-Threonine Kinases/*metabolism
Sarcoplasmic Reticulum Calcium-Transporting ATPases/*antagonists & inhibitors
Thapsigargin/*pharmacology
Adult ; Apoptosis/drug effects ; Brain/pathology ; Brain/surgery ; Brain Neoplasms/genetics ; Brain Neoplasms/mortality ; Brain Neoplasms/surgery ; Cell Line, Tumor ; Drug Resistance, Neoplasm/genetics ; Endoplasmic Reticulum Stress/drug effects ; Endoribonucleases/genetics ; Gene Expression Regulation, Neoplastic ; Glioblastoma/genetics ; Glioblastoma/mortality ; Glioblastoma/surgery ; Humans ; Insulin-Like Growth Factor Binding Protein 3/genetics ; Insulin-Like Growth Factor Binding Protein 3/metabolism ; Insulin-Like Growth Factor Binding Protein 5/genetics ; Insulin-Like Growth Factor Binding Protein 5/metabolism ; Primary Cell Culture ; Progression-Free Survival ; Protein Serine-Threonine Kinases/genetics ; RNA-Seq ; Signal Transduction/genetics ; Spheroids, Cellular ; Thapsigargin/analogs & derivatives ; Thapsigargin/therapeutic use ; Tumor Cells, Cultured ; Unfolded Protein Response/drug effects

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Skocz do pozycji: 20.

Tytuł:: IGFBP5 promotes angiogenic and neurogenic differentiation potential of dental pulp stem cells.
Autorzy:: Li J; Laboratory of Molecular Signaling and Stem Cells Therapy, Beijing Key Laboratory of Tooth Regeneration and Function Reconstruction, School of Stomatology Capital Medical University, Beijing, China.; Department of Preventive Dentistry, Beijing Stomatological Hospital，Capital Medical University, Beijing, China.
Diao S; Laboratory of Molecular Signaling and Stem Cells Therapy, Beijing Key Laboratory of Tooth Regeneration and Function Reconstruction, School of Stomatology Capital Medical University, Beijing, China.; Department of Pediatric Dentistry, Beijing Stomatological Hospital，Capital Medical University, Beijing, China.
Yang H; Laboratory of Molecular Signaling and Stem Cells Therapy, Beijing Key Laboratory of Tooth Regeneration and Function Reconstruction, School of Stomatology Capital Medical University, Beijing, China.
Cao Y; Laboratory of Molecular Signaling and Stem Cells Therapy, Beijing Key Laboratory of Tooth Regeneration and Function Reconstruction, School of Stomatology Capital Medical University, Beijing, China.
Du J; Laboratory of Molecular Signaling and Stem Cells Therapy, Beijing Key Laboratory of Tooth Regeneration and Function Reconstruction, School of Stomatology Capital Medical University, Beijing, China.; Molecular Laboratory for Gene Therapy and Tooth Regeneration, Beijing Key Laboratory of Tooth Regeneration and Function Reconstruction, school of Stomatology Capital Medical University, Beijing, China.
Yang D; Department of Pediatric Dentistry, Beijing Stomatological Hospital，Capital Medical University, Beijing, China.; Pokaż więcej
Źródło:: Development, growth & differentiation [Dev Growth Differ] 2019 Dec; Vol. 61 (9), pp. 457-465. Date of Electronic Publication: 2019 Oct 10.
Typ publikacji:: Journal Article
MeSH Terms:: Neovascularization, Physiologic*
Dental Pulp/*metabolism
Insulin-Like Growth Factor Binding Protein 5/*metabolism
Stem Cells/*metabolism
Cell Differentiation ; Cells, Cultured ; Dental Pulp/cytology ; Humans ; Stem Cells/cytology

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