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Wyszukujesz frazę ""Integrin"" wg kryterium: Temat


Tytuł:
Integrin alpha 6 is upregulated and drives hepatocellular carcinoma progression through integrin α6β4 complex.
Autorzy:
Zheng G; Department of Cell Systems & Anatomy, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.; Department of Clinical Laboratory, Qilu Hospital of Shandong University, Shandong, China.
Bouamar H; Department of Cell Systems & Anatomy, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Cserhati M; Department of Cell Systems & Anatomy, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Zeballos CR; Department of Cell Systems & Anatomy, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Mehta I; Department of Cell Systems & Anatomy, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Zare H; Department of Cell Systems & Anatomy, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Broome L; Department of Cell Systems & Anatomy, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Hu R; Department of Cell Systems & Anatomy, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Lai Z; Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.; Department of Molecular Medicine, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Chen Y; Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.; Department of Molecular Medicine, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.; Department of Population Health Sciences, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Sharkey FE; Department of Pathology and Laboratory Medicine, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Rani M; Transplant Center, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Halff GA; Transplant Center, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Cigarroa FG; Transplant Center, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Sun LZ; Department of Cell Systems & Anatomy, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
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Źródło:
International journal of cancer [Int J Cancer] 2022 Sep 15; Vol. 151 (6), pp. 930-943. Date of Electronic Publication: 2022 Jun 19.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Carcinoma, Hepatocellular*/genetics
Carcinoma, Hepatocellular*/pathology
Integrin alpha6*/genetics
Integrin alpha6*/metabolism
Integrin alpha6beta4*/genetics
Integrin alpha6beta4*/metabolism
Cell Line, Tumor ; Cell Proliferation ; Gene Expression Regulation, Neoplastic ; Humans ; Integrin beta4/genetics ; Integrin beta4/metabolism ; Liver Neoplasms/genetics ; Liver Neoplasms/pathology
Czasopismo naukowe
Tytuł:
SERPINA3C ameliorates adipose tissue inflammation through the Cathepsin G/Integrin/AKT pathway.
Autorzy:
Li BY; Key Laboratory of Metabolism and Molecular Medicine of the Ministry of Education, Department of Biochemistry and Molecular Biology of School of Basic Medical Sciences and Department of Endocrinology and Metabolism of Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Guo YY; Key Laboratory of Metabolism and Molecular Medicine of the Ministry of Education, Department of Biochemistry and Molecular Biology of School of Basic Medical Sciences and Department of Endocrinology and Metabolism of Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Xiao G; Key Laboratory of Metabolism and Molecular Medicine of the Ministry of Education, Department of Biochemistry and Molecular Biology of School of Basic Medical Sciences and Department of Endocrinology and Metabolism of Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Guo L; School of Kinesiology, and Shanghai Frontiers Science Research Base of Exercise and Metabolic Health, Shanghai University of Sport, Shanghai, 200438, China. Electronic address: .
Tang QQ; Key Laboratory of Metabolism and Molecular Medicine of the Ministry of Education, Department of Biochemistry and Molecular Biology of School of Basic Medical Sciences and Department of Endocrinology and Metabolism of Zhongshan Hospital, Fudan University, Shanghai, 200032, China. Electronic address: .
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Źródło:
Molecular metabolism [Mol Metab] 2022 Jul; Vol. 61, pp. 101500. Date of Electronic Publication: 2022 Apr 15.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Adipose Tissue*/metabolism
Cathepsin G*/metabolism
Cathepsin G*/pharmacology
Insulin Resistance*/physiology
Integrin alpha5beta1*/metabolism
Obesity*/etiology
Obesity*/metabolism
Serpins*/deficiency
Serpins*/metabolism
Adipocytes/metabolism ; Animals ; Diet, High-Fat/adverse effects ; Inflammation/drug therapy ; Inflammation/metabolism ; Integrin beta1/metabolism ; Integrins/metabolism ; Male ; Mice ; Mice, Knockout ; Proto-Oncogene Proteins c-akt/metabolism
Czasopismo naukowe
Tytuł:
Embigin is a fibronectin receptor that affects sebaceous gland differentiation and metabolism.
Autorzy:
Sipilä K; Centre for Gene Therapy & Regenerative Medicine, King's College London, London SE1 9RT, UK.
Rognoni E; Centre for Cell Biology and Cutaneous Research, Blizard Institute, Faculty of Medicine and Dentistry, Queen Mary University of London, London E1 2AT, UK.
Jokinen J; Department of Life Technologies, University of Turku, Turku 20014, Finland.
Tewary M; Centre for Gene Therapy & Regenerative Medicine, King's College London, London SE1 9RT, UK.
Vietri Rudan M; Centre for Gene Therapy & Regenerative Medicine, King's College London, London SE1 9RT, UK.
Talvi S; Department of Life Technologies, University of Turku, Turku 20014, Finland.
Jokinen V; Department of Life Technologies, University of Turku, Turku 20014, Finland.
Dahlström KM; Structural Bioinformatics Laboratory, InFLAMES Research Flagship Center, Faculty of Science and Engineering, Åbo Akademi University, Turku 20520, Finland.
Liakath-Ali K; Department of Molecular and Cellular Physiology, Stanford University, Stanford, CA 94305, USA.
Mobasseri A; Centre for Gene Therapy & Regenerative Medicine, King's College London, London SE1 9RT, UK.
Du-Harpur X; Centre for Gene Therapy & Regenerative Medicine, King's College London, London SE1 9RT, UK; The Francis Crick Institute, London NW1 1AT, UK.
Käpylä J; Department of Life Technologies, University of Turku, Turku 20014, Finland.
Nutt SL; The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, VIC 3052, Australia; Department of Medical Biology, University of Melbourne, Parkville, VIC 3010, Australia.
Salminen TA; Structural Bioinformatics Laboratory, InFLAMES Research Flagship Center, Faculty of Science and Engineering, Åbo Akademi University, Turku 20520, Finland.
Heino J; Department of Life Technologies, University of Turku, Turku 20014, Finland.
Watt FM; Centre for Gene Therapy & Regenerative Medicine, King's College London, London SE1 9RT, UK; European Molecular Biology Laboratory, Heidelberg 69117, Germany. Electronic address: .
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Źródło:
Developmental cell [Dev Cell] 2022 Jun 20; Vol. 57 (12), pp. 1453-1465.e7. Date of Electronic Publication: 2022 Jun 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Integrin alpha5beta1*
Sebaceous Glands*
Animals ; Cell Adhesion ; Cell Differentiation ; Fibronectins ; Integrin beta1 ; Integrins/metabolism ; Mice
Czasopismo naukowe
Tytuł:
Force-enhanced biophysical connectivity of platelet β3 integrin signaling through Talin is predicted by steered molecular dynamics simulations.
Autorzy:
Su S; Institute of Biomechanics/School of Biology and Biological Engineering, South China University of Technology, Guangzhou, 510006, China.
Ling Y; Institute of Biomechanics/School of Biology and Biological Engineering, South China University of Technology, Guangzhou, 510006, China.
Fang Y; Institute of Biomechanics/School of Biology and Biological Engineering, South China University of Technology, Guangzhou, 510006, China. .
Wu J; Institute of Biomechanics/School of Biology and Biological Engineering, South China University of Technology, Guangzhou, 510006, China. .
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Źródło:
Scientific reports [Sci Rep] 2022 Mar 17; Vol. 12 (1), pp. 4605. Date of Electronic Publication: 2022 Mar 17.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Integrin beta3*/metabolism
Talin*/metabolism
Integrin beta1/metabolism ; Mechanical Phenomena ; Molecular Dynamics Simulation ; Protein Binding
Czasopismo naukowe
Tytuł:
Contribution of Endothelial Laminin-Binding Integrins to Cellular Processes Associated with Angiogenesis.
Autorzy:
Xu H; Department of Regenerative and Cancer Cell Biology, Albany Medical College, 47 New Scotland Ave., Albany, NY 12208, USA.
LaFlamme SE; Department of Regenerative and Cancer Cell Biology, Albany Medical College, 47 New Scotland Ave., Albany, NY 12208, USA.
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Źródło:
Cells [Cells] 2022 Feb 26; Vol. 11 (5). Date of Electronic Publication: 2022 Feb 26.
Typ publikacji:
Journal Article
MeSH Terms:
Integrin alpha6beta4*/genetics
Integrin alpha6beta4*/metabolism
Laminin*/metabolism
Cell Adhesion/physiology ; Endothelial Cells/metabolism ; Integrin alpha3beta1/genetics ; Integrin alpha3beta1/metabolism
Czasopismo naukowe
Tytuł:
Integrin α 2 β 1 as a negative regulator of the laminin receptors α 6 β 1 and α 6 β 4 .
Autorzy:
Dao L; Center for Functional Nanostructures, Karlsruher Institut für Technologie (KIT), Wolfgang-Gaede-Strasse 1a, 76131, Karlsruhe, Germany.
Blaue C; Center for Functional Nanostructures, Karlsruher Institut für Technologie (KIT), Wolfgang-Gaede-Strasse 1a, 76131, Karlsruhe, Germany.
Franz CM; Center for Functional Nanostructures, Karlsruher Institut für Technologie (KIT), Wolfgang-Gaede-Strasse 1a, 76131, Karlsruhe, Germany; WPI Nano Life Science Institute, Kanazawa University, Kakuma-machi, Kanazawa, Japan. Electronic address: .
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Źródło:
Micron (Oxford, England : 1993) [Micron] 2021 Sep; Vol. 148, pp. 103106. Date of Electronic Publication: 2021 Jun 19.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Integrin alpha2beta1*/genetics
Receptors, Laminin*
Animals ; CHO Cells ; Cell Adhesion ; Cricetinae ; Cricetulus ; Humans ; Integrin alpha6beta1 ; Laminin
Czasopismo naukowe
Tytuł:
Sortase A-mediated cyclization of novel polycyclic RGD peptides for α ν β 3 integrin targeting.
Autorzy:
Chen Y; Anhui Engineering Laboratory for Medicinal and Food Homologous Natural Resources Exploration, Hefei Normal University, Hefei 230601, China.
Jia L; Anhui Engineering Laboratory for Medicinal and Food Homologous Natural Resources Exploration, Hefei Normal University, Hefei 230601, China.
Zhu G; Anhui Engineering Laboratory for Medicinal and Food Homologous Natural Resources Exploration, Hefei Normal University, Hefei 230601, China.
Wang W; Anhui Engineering Laboratory for Medicinal and Food Homologous Natural Resources Exploration, Hefei Normal University, Hefei 230601, China.
Geng M; Anhui Engineering Laboratory for Medicinal and Food Homologous Natural Resources Exploration, Hefei Normal University, Hefei 230601, China.
Lu H; Anhui Engineering Laboratory for Medicinal and Food Homologous Natural Resources Exploration, Hefei Normal University, Hefei 230601, China.
Zhang Y; Anhui Engineering Laboratory for Medicinal and Food Homologous Natural Resources Exploration, Hefei Normal University, Hefei 230601, China.
Zhou M; Anhui Engineering Laboratory for Medicinal and Food Homologous Natural Resources Exploration, Hefei Normal University, Hefei 230601, China.
Zhang F; Anhui Engineering Laboratory for Medicinal and Food Homologous Natural Resources Exploration, Hefei Normal University, Hefei 230601, China.
Cheng X; Anhui Engineering Laboratory for Medicinal and Food Homologous Natural Resources Exploration, Hefei Normal University, Hefei 230601, China. Electronic address: .
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Źródło:
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2022 Oct 01; Vol. 73, pp. 128888. Date of Electronic Publication: 2022 Jul 15.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Integrin alphaVbeta3*/metabolism
Integrin beta3*/metabolism
Aminoacyltransferases ; Bacterial Proteins ; Cyclization ; Cysteine Endopeptidases ; Oligopeptides/chemistry
Czasopismo naukowe
Tytuł:
Fibronectin and Integrin α5 play overlapping and independent roles in regulating the development of pharyngeal endoderm and cartilage.
Autorzy:
Gao Y; Department of Anatomy and Cell Biology, Carver College of Medicine, The University of Iowa, Iowa City, IA, 52242, USA.
Hu B; Department of Anatomy and Cell Biology, Carver College of Medicine, The University of Iowa, Iowa City, IA, 52242, USA.
Flores R; Department of Anatomy and Cell Biology, Carver College of Medicine, The University of Iowa, Iowa City, IA, 52242, USA.
Xie H; Department of Anatomy and Cell Biology, Carver College of Medicine, The University of Iowa, Iowa City, IA, 52242, USA.
Lin F; Department of Anatomy and Cell Biology, Carver College of Medicine, The University of Iowa, Iowa City, IA, 52242, USA. Electronic address: .
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Źródło:
Developmental biology [Dev Biol] 2022 Sep; Vol. 489, pp. 122-133. Date of Electronic Publication: 2022 Jun 19.
Typ publikacji:
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Endoderm*/metabolism
Integrin alpha5*/genetics
Integrin alpha5*/metabolism
Animals ; Branchial Region/metabolism ; Cartilage/metabolism ; Fibronectins/genetics ; Fibronectins/metabolism ; Gene Expression Regulation, Developmental ; Neural Crest ; Zebrafish/genetics ; Zebrafish/metabolism
Czasopismo naukowe
Tytuł:
The integrin ligand SVEP1 regulates GPCR-mediated vasoconstriction via integrins α9β1 and α4β1.
Autorzy:
Morris GE; Department of Cardiovascular Sciences, University of Leicester and National Institute for Health Research Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK.
Denniff MJ; Department of Cardiovascular Sciences, University of Leicester and National Institute for Health Research Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK.
Karamanavi E; Department of Cardiovascular Sciences, University of Leicester and National Institute for Health Research Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK.
Andrews SA; Department of Cardiovascular Sciences, University of Leicester and National Institute for Health Research Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK.
Kostogrys RB; Department of Human Nutrition, Faculty of Food Technology, University of Agriculture in Krakow, Krakow, Poland.
Bountziouka V; Department of Cardiovascular Sciences, University of Leicester and National Institute for Health Research Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK.
Ghaderi-Najafabadi M; Department of Cardiovascular Sciences, University of Leicester and National Institute for Health Research Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK.
Shamkhi N; Department of Cardiovascular Sciences, University of Leicester and National Institute for Health Research Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK.
McConnell G; Department of Cardiovascular Sciences, University of Leicester and National Institute for Health Research Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK.
Kaiser MA; Department of Cardiovascular Sciences, University of Leicester and National Institute for Health Research Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK.
Carleton L; Horizon Discovery Ltd., Cambridge, UK.
Schofield C; Horizon Discovery Ltd., Cambridge, UK.
Kessler T; Department of Cardiology, German Heart Centre Munich, Technical University of Munich, Munich, Germany.; German Centre of Cardiovascular Research (DZHK e. V.), Partner Site Munich Heart Alliance, Munich, Germany.
Rainbow RD; Department of Cardiovascular and Metabolic Medicine & Liverpool Centre for Cardiovascular Science, University of Liverpool, Liverpool, UK.
Samani NJ; Department of Cardiovascular Sciences, University of Leicester and National Institute for Health Research Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK.
Webb TR; Department of Cardiovascular Sciences, University of Leicester and National Institute for Health Research Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK.
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Źródło:
British journal of pharmacology [Br J Pharmacol] 2022 Nov; Vol. 179 (21), pp. 4958-4973. Date of Electronic Publication: 2022 Aug 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Induced Pluripotent Stem Cells*
Integrin alpha4beta1*
15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid ; Animals ; Calcium/metabolism ; Cell Adhesion Molecules ; Humans ; Integrins/genetics ; Integrins/metabolism ; Ligands ; Mice ; Vasoconstriction ; Vasoconstrictor Agents ; rho-Associated Kinases
Czasopismo naukowe
Tytuł:
Mesenchymal stem cell aggregation mediated by integrin α4/VCAM-1 after intrathecal transplantation in MCAO rats.
Autorzy:
Ran Y; Department of Neurology, The Chinese PLA General Hospital, Medical School of Chinese PLA, Beijing, 100853, China.
Dong Y; State Key Laboratory of Chemical Oncogenomics, Shenzhen Key Laboratory of Health Sciences and Technology, Institute of Biopharmaceutical and Health Engineering (iBHE), Shenzhen International Graduate School, Tsinghua University, Shenzhen, 518055, China.; School of Life Sciences, Tsinghua University, Beijing, 100084, China.
Li Y; State Key Laboratory of Chemical Oncogenomics, Shenzhen Key Laboratory of Health Sciences and Technology, Institute of Biopharmaceutical and Health Engineering (iBHE), Shenzhen International Graduate School, Tsinghua University, Shenzhen, 518055, China.; School of Life Sciences, Tsinghua University, Beijing, 100084, China.
Xie J; State Key Laboratory of Chemical Oncogenomics, Shenzhen Key Laboratory of Health Sciences and Technology, Institute of Biopharmaceutical and Health Engineering (iBHE), Shenzhen International Graduate School, Tsinghua University, Shenzhen, 518055, China.; Tsinghua-Berkeley Shenzhen Institute (TBSI), Tsinghua University, Shenzhen, 518055, China.
Zeng S; State Key Laboratory of Chemical Oncogenomics, Shenzhen Key Laboratory of Health Sciences and Technology, Institute of Biopharmaceutical and Health Engineering (iBHE), Shenzhen International Graduate School, Tsinghua University, Shenzhen, 518055, China.; Tsinghua-Berkeley Shenzhen Institute (TBSI), Tsinghua University, Shenzhen, 518055, China.
Liang C; State Key Laboratory of Chemical Oncogenomics, Shenzhen Key Laboratory of Health Sciences and Technology, Institute of Biopharmaceutical and Health Engineering (iBHE), Shenzhen International Graduate School, Tsinghua University, Shenzhen, 518055, China.; Tsinghua-Berkeley Shenzhen Institute (TBSI), Tsinghua University, Shenzhen, 518055, China.
Dai W; Department of Neurology, The Chinese PLA General Hospital, Medical School of Chinese PLA, Beijing, 100853, China.
Tang W; Department of Neurology, The Chinese PLA General Hospital, Medical School of Chinese PLA, Beijing, 100853, China.
Wu Y; State Key Laboratory of Chemical Oncogenomics, Shenzhen Key Laboratory of Health Sciences and Technology, Institute of Biopharmaceutical and Health Engineering (iBHE), Shenzhen International Graduate School, Tsinghua University, Shenzhen, 518055, China. .; Tsinghua-Berkeley Shenzhen Institute (TBSI), Tsinghua University, Shenzhen, 518055, China. .
Yu S; Department of Neurology, The Chinese PLA General Hospital, Medical School of Chinese PLA, Beijing, 100853, China. .
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Źródło:
Stem cell research & therapy [Stem Cell Res Ther] 2022 Oct 22; Vol. 13 (1), pp. 507. Date of Electronic Publication: 2022 Oct 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Infarction, Middle Cerebral Artery*/genetics
Infarction, Middle Cerebral Artery*/therapy
Integrin alpha4*/genetics
Integrin alpha4*/metabolism
Mesenchymal Stem Cell Transplantation*/methods
Mesenchymal Stem Cells*/metabolism
Vascular Cell Adhesion Molecule-1*/genetics
Vascular Cell Adhesion Molecule-1*/metabolism
Animals ; Rats
Czasopismo naukowe
Tytuł:
Integrin Alpha v Beta 6 (αvβ6) and Its Implications in Cancer Treatment.
Autorzy:
Brzozowska E; Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, St. R. Weigl 12, 53-114 Wroclaw, Poland.
Deshmukh S; Research and Development Department, Pure Biologics Ltd., 54-427 Wroclaw, Poland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Oct 15; Vol. 23 (20). Date of Electronic Publication: 2022 Oct 15.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Integrin alphaV*
Neoplasms*/therapy
Humans ; Aspartic Acid ; Integrins/metabolism ; Antigens, Neoplasm/metabolism ; Transforming Growth Factor beta/metabolism ; Oligopeptides ; Arginine ; Glycine
Czasopismo naukowe
Tytuł:
IGDQ motogenic peptide gradient induces directional cell migration through integrin (αv)β3 activation in MDA-MB-231 metastatic breast cancer cells.
Autorzy:
Ayama-Canden S; URBC - NARILIS, University of Namur, rue de Bruxelles 61, 5000 Namur, Belgium.
Tondo R; School of Chemistry, Cardiff University, Park Place, Main Building, CF10 3AT, Cardiff, Wales, United Kingdom.
Piñeros L; URBC - NARILIS, University of Namur, rue de Bruxelles 61, 5000 Namur, Belgium.
Ninane N; URBC - NARILIS, University of Namur, rue de Bruxelles 61, 5000 Namur, Belgium.
Demazy C; URBC - NARILIS, University of Namur, rue de Bruxelles 61, 5000 Namur, Belgium.
Dieu M; MaSUN, Mass Spectrometry Facility, University of Namur, 61, rue de Bruxelles, 5000 Namur, Belgium.
Fattaccioli A; URBC - NARILIS, University of Namur, rue de Bruxelles 61, 5000 Namur, Belgium.
Tabarrant T; LARN - NARILIS, University of Namur, rue de Bruxelles 61, 5000 Namur, Belgium.
Lucas S; LARN - NARILIS, University of Namur, rue de Bruxelles 61, 5000 Namur, Belgium.
Bonifazi D; School of Chemistry, Cardiff University, Park Place, Main Building, CF10 3AT, Cardiff, Wales, United Kingdom; Institute of Organic Chemistry, University of Vienna, Währinger Str. 38, 1090 Vienna, Austria.
Michiels C; URBC - NARILIS, University of Namur, rue de Bruxelles 61, 5000 Namur, Belgium. Electronic address: .
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Źródło:
Neoplasia (New York, N.Y.) [Neoplasia] 2022 Sep; Vol. 31, pp. 100816. Date of Electronic Publication: 2022 Jun 25.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Integrin alphaVbeta3*/genetics
Neoplasms*
Cell Adhesion/genetics ; Cell Line, Tumor ; Cell Movement/genetics ; Fibronectins/genetics ; Humans ; Peptides ; Proteomics
Czasopismo naukowe
Tytuł:
Activin A promotes human trophoblast invasion by upregulating integrin β3 via ALK4-SMAD4 signaling.
Autorzy:
Sun F; Center for Reproductive Medicine, Shandong University, Jinan, Shandong, 250012, China; Key Laboratory of Reproductive Endocrinology of Ministry of Education, Shandong University, Jinan, Shandong, 250012, China.
Cheng L; Center for Reproductive Medicine, Shandong University, Jinan, Shandong, 250012, China.
Guo L; Center for Reproductive Medicine, Shandong University, Jinan, Shandong, 250012, China; Key Laboratory of Reproductive Endocrinology of Ministry of Education, Shandong University, Jinan, Shandong, 250012, China.
Su S; Center for Reproductive Medicine, Shandong University, Jinan, Shandong, 250012, China; Key Laboratory of Reproductive Endocrinology of Ministry of Education, Shandong University, Jinan, Shandong, 250012, China.
Li Y; Center for Reproductive Medicine, Shandong University, Jinan, Shandong, 250012, China; Key Laboratory of Reproductive Endocrinology of Ministry of Education, Shandong University, Jinan, Shandong, 250012, China; Medical Integration and Practice Center, Shandong University, Jinan, Shandong, 250012, China; Suzhou Research Institute, Shandong University, Suzhou, Jiangsu, 215123, China. Electronic address: .
Yan J; Center for Reproductive Medicine, Shandong University, Jinan, Shandong, 250012, China; Key Laboratory of Reproductive Endocrinology of Ministry of Education, Shandong University, Jinan, Shandong, 250012, China. Electronic address: .
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Źródło:
Placenta [Placenta] 2022 Nov; Vol. 129, pp. 62-69. Date of Electronic Publication: 2022 Oct 10.
Typ publikacji:
Journal Article
MeSH Terms:
Trophoblasts*/metabolism
Integrin beta3*/metabolism
Pregnancy ; Female ; Humans ; Cell Movement/physiology ; Activins/metabolism ; Smad4 Protein/metabolism
Czasopismo naukowe
Tytuł:
Integrin β1 transduces the signal for LY6D-induced macropinocytosis and mediates senescence-inducing stress-evoked vacuole formation via FAK.
Autorzy:
Nakagawa K; Department of Biology, Graduate School of Science, Kobe University, Japan.
Nagano T; Biosignal Research Center, Kobe University, Japan.
Katasho R; Department of Biology, Graduate School of Science, Kobe University, Japan.
Iwasaki T; Department of Biology, Graduate School of Science, Kobe University, Japan.; Biosignal Research Center, Kobe University, Japan.
Kamada S; Department of Biology, Graduate School of Science, Kobe University, Japan.; Biosignal Research Center, Kobe University, Japan.
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Źródło:
FEBS letters [FEBS Lett] 2022 Nov; Vol. 596 (21), pp. 2768-2780. Date of Electronic Publication: 2022 Sep 02.
Typ publikacji:
Journal Article
MeSH Terms:
Integrin beta1*/genetics
Integrin beta1*/metabolism
Proteomics*
Vacuoles/metabolism ; Focal Adhesion Kinase 1/genetics ; Focal Adhesion Kinase 1/metabolism ; Focal Adhesion Protein-Tyrosine Kinases/metabolism ; Signal Transduction/physiology ; src-Family Kinases/metabolism ; Phosphorylation
Czasopismo naukowe
Tytuł:
Shear-Induced ITGB4 Promotes Endothelial Cell Inflammation and Atherosclerosis.
Autorzy:
Kong X; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, 210029, China.
Chen S; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, 210029, China.
Luo S; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, 210029, China.
Chen A; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, 210029, China.
Wang L; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, 210029, China.
Tang H; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, 210029, China.
Wang F; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, 210029, China.
Wang Z; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, 210029, China.
Gao X; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, 210029, China.; Department of Cardiology, Nanjing Heart Centre, Nanjing, China.
Zuo G; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, 210029, China.
Zhou W; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, 210029, China.
Gu Y; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, 210029, China.
Ge Z; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, 210029, China.
Zhang J; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, 210029, China.; Department of Cardiology, Nanjing Heart Centre, Nanjing, China.
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Źródło:
Oxidative medicine and cellular longevity [Oxid Med Cell Longev] 2022 Oct 25; Vol. 2022, pp. 5842677. Date of Electronic Publication: 2022 Oct 25 (Print Publication: 2022).
Typ publikacji:
Journal Article
MeSH Terms:
Integrin beta4*/genetics
Integrin beta4*/metabolism
Atherosclerosis*/pathology
Mice ; Humans ; Animals ; Human Umbilical Vein Endothelial Cells/metabolism ; Stress, Mechanical ; Inflammation/pathology ; NF-kappa B/metabolism
Czasopismo naukowe
Tytuł:
CD146 interaction with integrin β1 activates LATS1-YAP signaling and induces radiation-resistance in breast cancer cells.
Autorzy:
Liang Y; Department of Thyroid and Breast Surgery, Clinical Research Center, The First Affiliated Hospital of Shantou University Medical College (SUMC), 57 Changping Road, Shantou, 515000, China; Guangdong Provincial Key Laboratory for Diagnosis and Treatment of Breast Cancer, Shantou, 515000, China.
Zhou X; Department of Prenatal Diagnosis, The First Affiliated Hospital of SUMC, Shantou, 515000, China.
Xie Q; Guangdong Provincial Key Laboratory for Diagnosis and Treatment of Breast Cancer, Shantou, 515000, China; Department of Medical Oncology, Cancer Hospital of SUMC, Shantou, 515000, China.
Sun H; Department of Thyroid and Breast Surgery, Clinical Research Center, The First Affiliated Hospital of Shantou University Medical College (SUMC), 57 Changping Road, Shantou, 515000, China.
Huang K; Department of Thyroid and Breast Surgery, Clinical Research Center, The First Affiliated Hospital of Shantou University Medical College (SUMC), 57 Changping Road, Shantou, 515000, China.
Chen H; Guangdong Provincial Key Laboratory for Diagnosis and Treatment of Breast Cancer, Shantou, 515000, China.
Wang W; Guangdong Provincial Key Laboratory for Diagnosis and Treatment of Breast Cancer, Shantou, 515000, China; Department of Medical Oncology, Cancer Hospital of SUMC, Shantou, 515000, China.
Zhou B; Department of Biomedical Engineering, College of Engineering, Shantou University, Shantou, 515000, China.
Wei X; Department of Pathology, Cancer Hospital of SUMC, 515000, China.
Zeng; Guangdong Provincial Key Laboratory for Diagnosis and Treatment of Breast Cancer, Shantou, 515000, China; Department of Medical Oncology, Cancer Hospital of SUMC, Shantou, 515000, China. Electronic address: .
Lin H; Department of Thyroid and Breast Surgery, Clinical Research Center, The First Affiliated Hospital of Shantou University Medical College (SUMC), 57 Changping Road, Shantou, 515000, China; Guangdong Provincial Key Laboratory for Diagnosis and Treatment of Breast Cancer, Shantou, 515000, China. Electronic address: .
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Źródło:
Cancer letters [Cancer Lett] 2022 Oct 10; Vol. 546, pp. 215856. Date of Electronic Publication: 2022 Aug 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Integrin beta1*
Triple Negative Breast Neoplasms*
CD146 Antigen ; Cell Line, Tumor ; Humans ; Protein Serine-Threonine Kinases
Czasopismo naukowe
Tytuł:
Glucocorticoids increase the risk of preterm premature rupture of membranes possibly by inducing ITGA8 gene expression in the amnion.
Autorzy:
Okazaki Y; University of Tsukuba, Department of Obstetrics and Gynecology, Faculty of Medicine, Ibaraki, Japan; Department of Maternal-Fetal Biology, National Research Institute for Child Health and Development, Tokyo, Japan; Division of Maternal Medicine, Center of Maternal-Fetal, Neonatal and Reproductive Medicine, National Center for Child Heath and Development, Tokyo, Japan.
Taniguchi K; Department of Maternal-Fetal Biology, National Research Institute for Child Health and Development, Tokyo, Japan.
Miyamoto Y; Department of Reproductive Biology, National Research Institute for Child Health and Development, Tokyo, Japan.
Kinoshita S; Department of NCCHD Child Health and Development, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
Nakabayashi K; Department of Maternal-Fetal Biology, National Research Institute for Child Health and Development, Tokyo, Japan.
Kaneko K; Division of Maternal Medicine, Center of Maternal-Fetal, Neonatal and Reproductive Medicine, National Center for Child Heath and Development, Tokyo, Japan.
Hamada H; University of Tsukuba, Department of Obstetrics and Gynecology, Faculty of Medicine, Ibaraki, Japan.
Satoh T; University of Tsukuba, Department of Obstetrics and Gynecology, Faculty of Medicine, Ibaraki, Japan.
Murashima A; Division of Maternal Medicine, Center of Maternal-Fetal, Neonatal and Reproductive Medicine, National Center for Child Heath and Development, Tokyo, Japan.
Hata K; Department of Maternal-Fetal Biology, National Research Institute for Child Health and Development, Tokyo, Japan. Electronic address: .
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Źródło:
Placenta [Placenta] 2022 Oct; Vol. 128, pp. 73-82. Date of Electronic Publication: 2022 Aug 18.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Fetal Membranes, Premature Rupture*/metabolism
Glucocorticoids*/adverse effects
Integrin alpha Chains*/genetics
Integrin alpha Chains*/metabolism
Lupus Erythematosus, Systemic*/metabolism
Premature Birth*/metabolism
Amnion/metabolism ; Female ; Gene Expression ; Humans ; Infant, Newborn ; Pregnancy
SCR Disease Name:
Preterm Premature Rupture of the Membranes
Czasopismo naukowe
Tytuł:
Pro-Inflammatory Chemokines CCL5, CXCL12, and CX3CL1 Bind to and Activate Platelet Integrin αIIbβ3 in an Allosteric Manner.
Autorzy:
Takada YK; Department of Dermatology, School of Medicine, University of California-Davis, 4645 Second Ave., Research III Suite 3300, Sacramento, CA 95817, USA.; Department of Biochemistry and Molecular Medicine, University of California Davis School of Medicine, Sacramento, CA 95817, USA.
Fujita M; Department of Dermatology, School of Medicine, University of California-Davis, 4645 Second Ave., Research III Suite 3300, Sacramento, CA 95817, USA.
Takada Y; Department of Dermatology, School of Medicine, University of California-Davis, 4645 Second Ave., Research III Suite 3300, Sacramento, CA 95817, USA.; Department of Biochemistry and Molecular Medicine, University of California Davis School of Medicine, Sacramento, CA 95817, USA.
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Źródło:
Cells [Cells] 2022 Sep 29; Vol. 11 (19). Date of Electronic Publication: 2022 Sep 29.
Typ publikacji:
Journal Article
MeSH Terms:
Integrin alphaVbeta3*/metabolism
Platelet Glycoprotein GPIIb-IIIa Complex*/metabolism
Animals ; Chemokine CCL5 ; Cricetinae ; Cricetulus ; Endothelial Cells/metabolism ; Inflammation ; Ligands ; Proteoglycans ; Receptors, Chemokine
Czasopismo naukowe
Tytuł:
High-Resolution Conformational Analysis of RGDechi-Derived Peptides Based on a Combination of NMR Spectroscopy and MD Simulations.
Autorzy:
Acconcia C; Department of Environmental, Biological and Pharmaceutical Science and Technology, University of Campania-Luigi Vanvitelli, Via Vivaldi 43, 81100 Caserta, Italy.
Paladino A; Institute of Biostructures and Bioimaging, CNR, Via Castellino 101, 80131 Naples, Italy.
Valle MD; Department of Environmental, Biological and Pharmaceutical Science and Technology, University of Campania-Luigi Vanvitelli, Via Vivaldi 43, 81100 Caserta, Italy.
Farina B; Institute of Biostructures and Bioimaging, CNR, Via Castellino 101, 80131 Naples, Italy.; Advanced Accelerator Applications, A Novartis Company, Via Ribes, 510010 Colleretto Giacosa, Italy.
Del Gatto A; Institute of Biostructures and Bioimaging, CNR, Via Castellino 101, 80131 Naples, Italy.; Interdepartmental Center of Bioactive Peptide, University of Naples Federico II, Via Mezzocannone 16, 80134 Naples, Italy.
Gaetano SD; Institute of Biostructures and Bioimaging, CNR, Via Castellino 101, 80131 Naples, Italy.; Interdepartmental Center of Bioactive Peptide, University of Naples Federico II, Via Mezzocannone 16, 80134 Naples, Italy.
Capasso D; Interdepartmental Center of Bioactive Peptide, University of Naples Federico II, Via Mezzocannone 16, 80134 Naples, Italy.; Center for Life Sciences and Technologies (CESTEV), University of Naples Federico II, Via De Amicis 95, 80145 Naples, Italy.
Gentile MT; Department of Environmental, Biological and Pharmaceutical Science and Technology, University of Campania-Luigi Vanvitelli, Via Vivaldi 43, 81100 Caserta, Italy.
Malgieri G; Department of Environmental, Biological and Pharmaceutical Science and Technology, University of Campania-Luigi Vanvitelli, Via Vivaldi 43, 81100 Caserta, Italy.
Isernia C; Department of Environmental, Biological and Pharmaceutical Science and Technology, University of Campania-Luigi Vanvitelli, Via Vivaldi 43, 81100 Caserta, Italy.
Saviano M; Institute of Crystallography, CNR, URT Caserta, Via Vivaldi 43, 81100 Caserta, Italy.
Fattorusso R; Department of Environmental, Biological and Pharmaceutical Science and Technology, University of Campania-Luigi Vanvitelli, Via Vivaldi 43, 81100 Caserta, Italy.
Zaccaro L; Institute of Biostructures and Bioimaging, CNR, Via Castellino 101, 80131 Naples, Italy.; Interdepartmental Center of Bioactive Peptide, University of Naples Federico II, Via Mezzocannone 16, 80134 Naples, Italy.
Russo L; Department of Environmental, Biological and Pharmaceutical Science and Technology, University of Campania-Luigi Vanvitelli, Via Vivaldi 43, 81100 Caserta, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Sep 20; Vol. 23 (19). Date of Electronic Publication: 2022 Sep 20.
Typ publikacji:
Journal Article
MeSH Terms:
Integrin alphaVbeta3*/metabolism
Peptides*/chemistry
Magnetic Resonance Spectroscopy ; Oligopeptides/chemistry ; Pharmaceutical Preparations
Czasopismo naukowe
Tytuł:
A general chemical principle for creating closure-stabilizing integrin inhibitors.
Autorzy:
Lin FY; Department of Biological Chemistry and Molecular Pharmacology, Program in Cellular and Molecular Medicine, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Li J; Department of Biological Chemistry and Molecular Pharmacology, Program in Cellular and Molecular Medicine, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Xie Y; School of Pharmaceutical Sciences, Tsinghua University, Beijing 100084, PRC.
Zhu J; Department of Biological Chemistry and Molecular Pharmacology, Program in Cellular and Molecular Medicine, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Huong Nguyen TT; Blood Research Institute, Versiti, Milwaukee, WI 53226, USA; Department of Biochemistry, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Zhang Y; School of Pharmaceutical Sciences, Tsinghua University, Beijing 100084, PRC. Electronic address: .
Zhu J; Department of Biological Chemistry and Molecular Pharmacology, Program in Cellular and Molecular Medicine, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA; Blood Research Institute, Versiti, Milwaukee, WI 53226, USA; Department of Biochemistry, Medical College of Wisconsin, Milwaukee, WI 53226, USA. Electronic address: .
Springer TA; Department of Biological Chemistry and Molecular Pharmacology, Program in Cellular and Molecular Medicine, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA. Electronic address: .
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Źródło:
Cell [Cell] 2022 Sep 15; Vol. 185 (19), pp. 3533-3550.e27.
Typ publikacji:
Journal Article
MeSH Terms:
Drug Design*
Integrin alpha4beta1*
Protein Conformation ; Serine ; Water
Czasopismo naukowe

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