Temat: "Integrin beta1" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: StarD7 deficiency hinders cell motility through p-ERK1/2/Cx43 reduction.
Autorzy:: Cruz Del Puerto M; Departamento de Bioquímica Clínica, Universidad Nacional de Córdoba, Facultad de Ciencias Químicas, Ciudad Universitaria, Córdoba, Argentina.; Consejo Nacional de Investigaciones Científicas y Tecnológicas (CONICET), Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI), Ciudad Universitaria, Córdoba, Argentina.
Rojas ML; Departamento de Bioquímica Clínica, Universidad Nacional de Córdoba, Facultad de Ciencias Químicas, Ciudad Universitaria, Córdoba, Argentina.; Consejo Nacional de Investigaciones Científicas y Tecnológicas (CONICET), Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI), Ciudad Universitaria, Córdoba, Argentina.
Racca AC; Departamento de Bioquímica Clínica, Universidad Nacional de Córdoba, Facultad de Ciencias Químicas, Ciudad Universitaria, Córdoba, Argentina.; Consejo Nacional de Investigaciones Científicas y Tecnológicas (CONICET), Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI), Ciudad Universitaria, Córdoba, Argentina.
Kourdova LT; Departamento de Bioquímica Clínica, Universidad Nacional de Córdoba, Facultad de Ciencias Químicas, Ciudad Universitaria, Córdoba, Argentina.; Consejo Nacional de Investigaciones Científicas y Tecnológicas (CONICET), Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI), Ciudad Universitaria, Córdoba, Argentina.
Miranda AL; Departamento de Bioquímica Clínica, Universidad Nacional de Córdoba, Facultad de Ciencias Químicas, Ciudad Universitaria, Córdoba, Argentina.; Consejo Nacional de Investigaciones Científicas y Tecnológicas (CONICET), Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI), Ciudad Universitaria, Córdoba, Argentina.
Panzetta-Dutari G; Departamento de Bioquímica Clínica, Universidad Nacional de Córdoba, Facultad de Ciencias Químicas, Ciudad Universitaria, Córdoba, Argentina.; Consejo Nacional de Investigaciones Científicas y Tecnológicas (CONICET), Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI), Ciudad Universitaria, Córdoba, Argentina.
Genti-Raimondi S; Departamento de Bioquímica Clínica, Universidad Nacional de Córdoba, Facultad de Ciencias Químicas, Ciudad Universitaria, Córdoba, Argentina.; Consejo Nacional de Investigaciones Científicas y Tecnológicas (CONICET), Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI), Ciudad Universitaria, Córdoba, Argentina.
Flores-Martín JB; Departamento de Bioquímica Clínica, Universidad Nacional de Córdoba, Facultad de Ciencias Químicas, Ciudad Universitaria, Córdoba, Argentina.; Consejo Nacional de Investigaciones Científicas y Tecnológicas (CONICET), Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI), Ciudad Universitaria, Córdoba, Argentina.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2022 Dec 30; Vol. 17 (12), pp. e0279912. Date of Electronic Publication: 2022 Dec 30 (Print Publication: 2022).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Carrier Proteins*/metabolism
Connexin 43*/genetics
Connexin 43*/metabolism
Integrin beta1/genetics ; Integrin beta1/metabolism ; MAP Kinase Signaling System ; Cell Movement/genetics ; Protein Isoforms/metabolism

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Skocz do pozycji: 2.

Tytuł:: An innovative strategy to identify new targets for delivering antibodies to the brain has led to the exploration of the integrin family.
Autorzy:: Cegarra C; Rare and Neurologic Diseases Research Therapeutic Area, Sanofi, Chilly Mazarin, France.
Cameron B; Biological Research, Sanofi, Vitry-Sur-Seine, France.
Chaves C; Rare and Neurologic Diseases Research Therapeutic Area, Sanofi, Chilly Mazarin, France.
Dabdoubi T; Biological Research, Sanofi, Vitry-Sur-Seine, France.
Do TM; Rare and Neurologic Diseases Research Therapeutic Area, Sanofi, Chilly Mazarin, France.
Genêt B; Integrated Drug Discovery, Sanofi, Vitry-Sur-Seine, France.
Roudières V; Rare and Neurologic Diseases Research Therapeutic Area, Sanofi, Chilly Mazarin, France.
Shi Y; Histology, Translational Sciences, Sanofi, Vitry-Sur-Seine, France.
Tchepikoff P; Histology, Translational Sciences, Sanofi, Vitry-Sur-Seine, France.
Lesuisse D; Rare and Neurologic Diseases Research Therapeutic Area, Sanofi, Chilly Mazarin, France.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2022 Sep 15; Vol. 17 (9), pp. e0274667. Date of Electronic Publication: 2022 Sep 15 (Print Publication: 2022).
Typ publikacji:: Journal Article
MeSH Terms:: Endothelial Cells*/metabolism
Integrins*/metabolism
Activated-Leukocyte Cell Adhesion Molecule ; Animals ; Antibodies/metabolism ; Brain/metabolism ; Integrin beta1/metabolism ; Mice

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Skocz do pozycji: 3.

Tytuł:: Vitronectin-derived bioactive peptide prevents spondyloarthritis by modulating Th17/Treg imbalance in mice with curdlan-induced spondyloarthritis.
Autorzy:: Min HK; Division of Rheumatology, Department of Internal Medicine, Konkuk University Medical Center, Seoul, Republic of Korea.
Choi J; Rheumatism Research Center, Catholic Research Institute of Medical Science, The Catholic University of Korea, Seoul, Republic of Korea.
Lee SY; Rheumatism Research Center, Catholic Research Institute of Medical Science, The Catholic University of Korea, Seoul, Republic of Korea.
Lee AR; Rheumatism Research Center, Catholic Research Institute of Medical Science, The Catholic University of Korea, Seoul, Republic of Korea.; Department of Biomedicine & Health Sciences, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Min BM; Department of Oral Biochemistry and Program in Cancer and Developmental Biology, Dental Research Institute, Seoul National University School of Dentistry, Seoul, Republic of Korea.
Cho ML; Rheumatism Research Center, Catholic Research Institute of Medical Science, The Catholic University of Korea, Seoul, Republic of Korea.; Department of Biomedicine & Health Sciences, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.; Laboratory of Immune Network, Conversant Research Consortium in Immunologic disease, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Park SH; Rheumatism Research Center, Catholic Research Institute of Medical Science, The Catholic University of Korea, Seoul, Republic of Korea.; Division of Rheumatology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2022 Jan 05; Vol. 17 (1), pp. e0262183. Date of Electronic Publication: 2022 Jan 05 (Print Publication: 2022).
Typ publikacji:: Journal Article
MeSH Terms:: Celecoxib/*administration & dosage
Peptides/*administration & dosage
Spondylarthritis/*drug therapy
T-Lymphocytes, Regulatory/*metabolism
Th17 Cells/*metabolism
Vitronectin/*chemistry
beta-Glucans/*adverse effects
Animals ; Celecoxib/pharmacology ; Cytokines/genetics ; Cytokines/metabolism ; Disease Models, Animal ; Disease Progression ; Female ; Gene Expression Regulation/drug effects ; Humans ; Integrin alphaVbeta3/metabolism ; Integrin beta1/metabolism ; Mice ; Peptides/pharmacology ; STAT3 Transcription Factor/genetics ; STAT3 Transcription Factor/metabolism ; Signal Transduction ; Spleen/immunology ; Spondylarthritis/chemically induced ; Spondylarthritis/genetics ; Spondylarthritis/immunology

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Skocz do pozycji: 4.

Tytuł:: Integrin beta 1 inhibition alleviates the chronic hyperproliferative dermatitis phenotype of SHARPIN-deficient mice.
Autorzy:: Peuhu E; Turku Centre for Biotechnology, University of Turku, Turku, Finland.
Salomaa SI; Turku Centre for Biotechnology, University of Turku, Turku, Finland.; Turku Drug Research Doctoral Programme, University of Turku, Turku, Finland.
De Franceschi N; Turku Centre for Biotechnology, University of Turku, Turku, Finland.
Potter CS; The Jackson Laboratory, Bar Harbor, Maine, United States of America.
Sundberg JP; The Jackson Laboratory, Bar Harbor, Maine, United States of America.
Pouwels J; Turku Centre for Biotechnology, University of Turku, Turku, Finland.; TEHO adaptive clinical trial design, University of Helsinki, Helsinki, Finland.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2017 Oct 17; Vol. 12 (10), pp. e0186628. Date of Electronic Publication: 2017 Oct 17 (Print Publication: 2017).
Typ publikacji:: Journal Article
MeSH Terms:: Carrier Proteins/*genetics
Dermatitis/*drug therapy
Epidermis/*drug effects
Integrin beta1/*genetics
Keratinocytes/*drug effects
Receptors, Tumor Necrosis Factor, Type I/*genetics
Animals ; Antibodies, Neutralizing/pharmacology ; Apoptosis ; Carrier Proteins/immunology ; Cell Proliferation ; Chronic Disease ; Dermatitis/genetics ; Dermatitis/immunology ; Dermatitis/pathology ; Epidermis/immunology ; Epidermis/pathology ; Female ; Gene Deletion ; Gene Expression Regulation ; Inflammation ; Integrin beta1/immunology ; Intracellular Signaling Peptides and Proteins ; Keratinocytes/immunology ; Keratinocytes/pathology ; Male ; Mice ; Mice, Knockout ; NF-kappa B/genetics ; NF-kappa B/immunology ; Phenotype ; Receptors, Tumor Necrosis Factor, Type I/deficiency ; Receptors, Tumor Necrosis Factor, Type I/immunology ; Signal Transduction ; Ubiquitin/genetics ; Ubiquitin/immunology

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Skocz do pozycji: 5.

Tytuł:: Proton beam irradiation inhibits the migration of melanoma cells.
Autorzy:: Jasińska-Konior K; Department of Biophysics, Faculty of Biochemistry, Biophysics and Biotechnology, Cracow, Poland.
Pochylczuk K; Department of Biophysics, Faculty of Biochemistry, Biophysics and Biotechnology, Cracow, Poland.
Czajka E; Department of Biophysics, Faculty of Biochemistry, Biophysics and Biotechnology, Cracow, Poland.
Michalik M; Department of Cell Biology, Faculty of Biochemistry, Biophysics and Biotechnology, Cracow, Poland.
Romanowska-Dixon B; Department of Ophthalmology and Ophthalmic Oncology, Jagiellonian University Medical College, Cracow, Poland.
Swakoń J; Institute of Nuclear Physics, PAS, Cracow, Poland.
Urbańska K; Department of Biophysics, Faculty of Biochemistry, Biophysics and Biotechnology, Cracow, Poland.
Elas M; Department of Biophysics, Faculty of Biochemistry, Biophysics and Biotechnology, Cracow, Poland.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2017 Oct 10; Vol. 12 (10), pp. e0186002. Date of Electronic Publication: 2017 Oct 10 (Print Publication: 2017).
Typ publikacji:: Journal Article
MeSH Terms:: Proton Therapy*
Cell Movement/*radiation effects
Integrin beta1/*genetics
Melanocytes/*radiation effects
Vimentin/*genetics
Cell Line, Tumor ; Cell Survival/radiation effects ; Clone Cells ; Gene Expression/radiation effects ; Humans ; Integrin beta1/metabolism ; Melanocytes/metabolism ; Melanocytes/pathology ; Organ Specificity ; Time-Lapse Imaging ; Vimentin/metabolism ; X-Rays

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Skocz do pozycji: 6.

Tytuł:: The characterization of exosomes from fibrosarcoma cell and the useful usage of Dynamic Light Scattering (DLS) for their evaluation.
Autorzy:: Lyu TS; College of Transdisciplinary Studies, School of Undergraduate Studies, DGIST, Daegu, Korea.
Ahn Y; College of Transdisciplinary Studies, School of Undergraduate Studies, DGIST, Daegu, Korea.
Im YJ; College of Transdisciplinary Studies, School of Undergraduate Studies, DGIST, Daegu, Korea.
Kim SS; College of Transdisciplinary Studies, School of Undergraduate Studies, DGIST, Daegu, Korea.
Lee KH; College of Transdisciplinary Studies, School of Undergraduate Studies, DGIST, Daegu, Korea.
Kim J; College of Transdisciplinary Studies, School of Undergraduate Studies, DGIST, Daegu, Korea.
Choi Y; College of Transdisciplinary Studies, School of Undergraduate Studies, DGIST, Daegu, Korea.
Lee D; College of Transdisciplinary Studies, School of Undergraduate Studies, DGIST, Daegu, Korea.
Kang E; College of Transdisciplinary Studies, School of Undergraduate Studies, DGIST, Daegu, Korea.
Jin G; College of Transdisciplinary Studies, School of Undergraduate Studies, DGIST, Daegu, Korea.
Hwang J; College of Transdisciplinary Studies, School of Undergraduate Studies, DGIST, Daegu, Korea.
Lee SI; College of Transdisciplinary Studies, School of Undergraduate Studies, DGIST, Daegu, Korea.; Department of New Biology, Graduate School, DGIST, Daegu, Korea.
Cho JA; College of Transdisciplinary Studies, School of Undergraduate Studies, DGIST, Daegu, Korea.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2021 Jan 26; Vol. 16 (1), pp. e0231994. Date of Electronic Publication: 2021 Jan 26 (Print Publication: 2021).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Exosomes/*metabolism
Fibrosarcoma/*metabolism
Cell Line, Tumor ; DNA-Binding Proteins/metabolism ; Dynamic Light Scattering ; Endosomal Sorting Complexes Required for Transport/metabolism ; Extracellular Vesicles/metabolism ; Female ; HSC70 Heat-Shock Proteins/metabolism ; Humans ; Integrin beta1/metabolism ; Tetraspanin 28/metabolism ; Tetraspanin 30/metabolism ; Transcription Factors/metabolism

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Skocz do pozycji: 7.

Tytuł:: Patient-derived and artificial ascites have minor effects on MeT-5A mesothelial cells and do not facilitate ovarian cancer cell adhesion.
Autorzy:: Estermann M; Adolphe Merkle Institute, University of Fribourg, Fribourg, Switzerland.
Huang YL; Department of Biomedicine, University Hospital Basel and University of Basel, Basel, Switzerland.
Septiadi D; Adolphe Merkle Institute, University of Fribourg, Fribourg, Switzerland.
Ritz D; Proteomics Core Facility, Biozentrum, University of Basel, Basel, Switzerland.
Liang CY; Department of Biomedicine, University Hospital Basel and University of Basel, Basel, Switzerland.
Jacob F; Department of Biomedicine, University Hospital Basel and University of Basel, Basel, Switzerland.
Drasler B; Adolphe Merkle Institute, University of Fribourg, Fribourg, Switzerland.
Petri-Fink A; Adolphe Merkle Institute, University of Fribourg, Fribourg, Switzerland.; Department of Chemistry, University of Fribourg, Fribourg, Switzerland.
Heinzelmann-Schwarz V; Department of Biomedicine, University Hospital Basel and University of Basel, Basel, Switzerland.
Rothen-Rutishauser B; Adolphe Merkle Institute, University of Fribourg, Fribourg, Switzerland.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2020 Dec 03; Vol. 15 (12), pp. e0241500. Date of Electronic Publication: 2020 Dec 03 (Print Publication: 2020).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cell Adhesion/*drug effects
Cytokines/*pharmacology
Neoplasms, Mesothelial/*drug therapy
Ovarian Neoplasms/*drug therapy
Ascites/metabolism ; Ascites/pathology ; Cell Line, Tumor ; Cytokines/metabolism ; Epithelial Cells/metabolism ; Epithelial Cells/pathology ; Female ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; Hyaluronan Receptors/genetics ; Integrin beta1/genetics ; Intercellular Adhesion Molecule-1/genetics ; Neoplasms, Mesothelial/genetics ; Neoplasms, Mesothelial/metabolism ; Neoplasms, Mesothelial/pathology ; Ovarian Neoplasms/genetics ; Ovarian Neoplasms/metabolism ; Ovarian Neoplasms/pathology ; Patients ; Peritoneum/chemistry ; Peritoneum/metabolism ; Signal Transduction/genetics ; cdc42 GTP-Binding Protein/genetics

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Skocz do pozycji: 8.

Tytuł:: RECK-Mediated β1-Integrin Regulation by TGF-β1 Is Critical for Wound Contraction in Mice.
Autorzy:: Gutiérrez J; Cellular Signaling and Differentiation Laboratory (CSDL), School of Medical Technology, Health Sciences Faculty, Universidad San Sebastian, Santiago, Chile; Centro de Regeneración y Envejecimiento (CARE), Departamento de Biología Celular y Molecular, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago, Chile.
Droppelmann CA; Centro de Regeneración y Envejecimiento (CARE), Departamento de Biología Celular y Molecular, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago, Chile; Molecular Medicine Group, Robarts Research Institute, Western University, London, Ontario, Canada.
Contreras O; Centro de Regeneración y Envejecimiento (CARE), Departamento de Biología Celular y Molecular, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago, Chile.
Takahashi C; Oncology and Molecular Biology, Cancer and Stem Cell Research Program, Cancer Research Institute, Kanazawa University, Kanazawa, Japan.
Brandan E; Centro de Regeneración y Envejecimiento (CARE), Departamento de Biología Celular y Molecular, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago, Chile.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2015 Aug 06; Vol. 10 (8), pp. e0135005. Date of Electronic Publication: 2015 Aug 06 (Print Publication: 2015).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: GPI-Linked Proteins/*genetics
Integrin beta1/*metabolism
Transforming Growth Factor beta1/*metabolism
Wound Healing/*genetics
Wounds, Nonpenetrating/*metabolism
Animals ; Extracellular Matrix/chemistry ; Extracellular Matrix/metabolism ; Fibroblasts/metabolism ; Fibroblasts/pathology ; Focal Adhesion Kinase 1/genetics ; Focal Adhesion Kinase 1/metabolism ; GPI-Linked Proteins/deficiency ; Gene Expression Regulation ; Hemizygote ; Integrin beta1/genetics ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; NIH 3T3 Cells ; Primary Cell Culture ; Signal Transduction ; Skin/injuries ; Skin/metabolism ; Transforming Growth Factor beta1/genetics ; Wounds, Nonpenetrating/genetics ; Wounds, Nonpenetrating/pathology

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Skocz do pozycji: 9.

Tytuł:: The use of mixed collagen-Matrigel matrices of increasing complexity recapitulates the biphasic role of cell adhesion in cancer cell migration: ECM sensing, remodeling and forces at the leading edge of cancer invasion.
Autorzy:: Anguiano M; IDISNA, Ciberonc and Solid Tumours and Biomarkers Program, Center for Applied Medical Research, University of Navarra, Pamplona, Spain.
Morales X; IDISNA, Ciberonc and Solid Tumours and Biomarkers Program, Center for Applied Medical Research, University of Navarra, Pamplona, Spain.
Castilla C; IDISNA, Ciberonc and Solid Tumours and Biomarkers Program, Center for Applied Medical Research, University of Navarra, Pamplona, Spain.
Pena AR; IDISNA, Ciberonc and Solid Tumours and Biomarkers Program, Center for Applied Medical Research, University of Navarra, Pamplona, Spain.
Ederra C; IDISNA, Ciberonc and Solid Tumours and Biomarkers Program, Center for Applied Medical Research, University of Navarra, Pamplona, Spain.
Martínez M; Neuroimaging Laboratory, Division of Neurosciences, Center for Applied Medical Research, University of Navarra, Pamplona, Spain.
Ariz M; IDISNA, Ciberonc and Solid Tumours and Biomarkers Program, Center for Applied Medical Research, University of Navarra, Pamplona, Spain.
Esparza M; IDISNA, Ciberonc and Solid Tumours and Biomarkers Program, Center for Applied Medical Research, University of Navarra, Pamplona, Spain.
Amaveda H; Department of Mechanical Engineering, Multiscale in Mechanical and Biological Engineering (M2BE), Aragon Institute of Engineering Research (I3A), University of Zaragoza, Zaragoza, Spain.
Mora M; Department of Mechanical Engineering, Multiscale in Mechanical and Biological Engineering (M2BE), Aragon Institute of Engineering Research (I3A), University of Zaragoza, Zaragoza, Spain.
Movilla N; Department of Mechanical Engineering, Multiscale in Mechanical and Biological Engineering (M2BE), Aragon Institute of Engineering Research (I3A), University of Zaragoza, Zaragoza, Spain.
Aznar JMG; Department of Mechanical Engineering, Multiscale in Mechanical and Biological Engineering (M2BE), Aragon Institute of Engineering Research (I3A), University of Zaragoza, Zaragoza, Spain.
Cortés-Domínguez I; IDISNA, Ciberonc and Solid Tumours and Biomarkers Program, Center for Applied Medical Research, University of Navarra, Pamplona, Spain.
Ortiz-de-Solorzano C; IDISNA, Ciberonc and Solid Tumours and Biomarkers Program, Center for Applied Medical Research, University of Navarra, Pamplona, Spain.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2020 Jan 16; Vol. 15 (1), pp. e0220019. Date of Electronic Publication: 2020 Jan 16 (Print Publication: 2020).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Mechanotransduction, Cellular*
Collagen/*pharmacology
Epithelial Cells/*drug effects
Extracellular Matrix/*drug effects
Focal Adhesions/*drug effects
Laminin/*pharmacology
Proteoglycans/*pharmacology
Cell Adhesion/drug effects ; Cell Line, Tumor ; Cell Movement/drug effects ; Collagen/chemistry ; Drug Combinations ; Epithelial Cells/metabolism ; Epithelial Cells/pathology ; Extracellular Matrix/chemistry ; Extracellular Matrix/metabolism ; Focal Adhesions/ultrastructure ; Gene Expression ; Humans ; Integrin beta1/genetics ; Integrin beta1/metabolism ; Laminin/chemistry ; Models, Biological ; Proteoglycans/chemistry ; Respiratory Mucosa/drug effects ; Respiratory Mucosa/metabolism ; Respiratory Mucosa/pathology ; Surface Properties ; Tumor Microenvironment/drug effects

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Skocz do pozycji: 10.

Tytuł:: β1-Integrin and integrin linked kinase regulate astrocytic differentiation of neural stem cells.
Autorzy:: Pan L; Department of Neurology, Northwestern University, Chicago, Illinois, United States of America.
North HA; Department of Neurology, Northwestern University, Chicago, Illinois, United States of America.
Sahni V; Department of Neurology, Northwestern University, Chicago, Illinois, United States of America.
Jeong SJ; Department of Neurology, Northwestern University, Chicago, Illinois, United States of America.
Mcguire TL; Department of Neurology, Northwestern University, Chicago, Illinois, United States of America.
Berns EJ; Department of Biomedical Engineering, Northwestern University, Evanston, Illinois, United States of America.
Stupp SI; Department of Materials Science and Engineering, Northwestern University, Evanston, Illinois, United States of America; Department of Chemistry, Northwestern University, Evanston, Illinois, United States of America; Department of Medicine and Institute for BioNanotechnology in Medicine, Northwestern University, Chicago, Illinois, United States of America.
Kessler JA; Department of Neurology, Northwestern University, Chicago, Illinois, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2014 Aug 06; Vol. 9 (8), pp. e104335. Date of Electronic Publication: 2014 Aug 06 (Print Publication: 2014).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Astrocytes/*metabolism
Cell Differentiation/*physiology
Integrin beta1/*metabolism
Neural Stem Cells/*metabolism
Protein Serine-Threonine Kinases/*metabolism
Signal Transduction/*physiology
Animals ; Astrocytes/cytology ; Cell Differentiation/drug effects ; Epitopes/pharmacology ; Integrin beta1/genetics ; Laminin/pharmacology ; Mice ; Neural Stem Cells/cytology ; Oligopeptides/pharmacology ; Peptide Fragments/pharmacology ; Protein Serine-Threonine Kinases/genetics ; Rats ; Rats, Long-Evans ; Signal Transduction/drug effects

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Skocz do pozycji: 11.

Tytuł:: C1GALT1 promotes invasive phenotypes of hepatocellular carcinoma cells by modulating integrin β1 glycosylation and activity.
Autorzy:: Liu CH; Graduate Institute of Anatomy and Cell Biology, National Taiwan University College of Medicine, Taipei, Taiwan.
Hu RH; Department of Surgery, National Taiwan University Hospital, Taipei, Taiwan.
Huang MJ; Graduate Institute of Anatomy and Cell Biology, National Taiwan University College of Medicine, Taipei, Taiwan; Research Center for Developmental Biology and Regenerative Medicine, National Taiwan University, Taipei, Taiwan.
Lai IR; Graduate Institute of Anatomy and Cell Biology, National Taiwan University College of Medicine, Taipei, Taiwan; Department of Surgery, National Taiwan University Hospital, Taipei, Taiwan.
Chen CH; Graduate Institute of Anatomy and Cell Biology, National Taiwan University College of Medicine, Taipei, Taiwan.
Lai HS; Department of Surgery, National Taiwan University Hospital, Taipei, Taiwan.
Wu YM; Department of Surgery, National Taiwan University Hospital, Taipei, Taiwan; Research Center for Developmental Biology and Regenerative Medicine, National Taiwan University, Taipei, Taiwan.
Huang MC; Graduate Institute of Anatomy and Cell Biology, National Taiwan University College of Medicine, Taipei, Taiwan; Research Center for Developmental Biology and Regenerative Medicine, National Taiwan University, Taipei, Taiwan.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2014 Aug 04; Vol. 9 (8), pp. e94995. Date of Electronic Publication: 2014 Aug 04 (Print Publication: 2014).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Gene Expression Regulation, Neoplastic*
Carcinoma, Hepatocellular/*genetics
Galactosyltransferases/*genetics
Integrin beta1/*genetics
Liver Neoplasms, Experimental/*genetics
Lung Neoplasms/*genetics
Animals ; Antibodies, Neutralizing/pharmacology ; Carcinoma, Hepatocellular/drug therapy ; Carcinoma, Hepatocellular/metabolism ; Carcinoma, Hepatocellular/secondary ; Cell Adhesion/drug effects ; Cell Line, Tumor ; Cell Movement/drug effects ; Extracellular Matrix Proteins/genetics ; Extracellular Matrix Proteins/metabolism ; Female ; Galactosyltransferases/antagonists & inhibitors ; Galactosyltransferases/metabolism ; Glycosylation ; Humans ; Integrin beta1/metabolism ; Liver Neoplasms, Experimental/drug therapy ; Liver Neoplasms, Experimental/metabolism ; Liver Neoplasms, Experimental/pathology ; Lung Neoplasms/drug therapy ; Lung Neoplasms/metabolism ; Lung Neoplasms/secondary ; Mice ; Mice, SCID ; Neoplasm Invasiveness ; Polysaccharides/chemistry ; Polysaccharides/metabolism ; Protein Binding ; RNA, Small Interfering/genetics ; RNA, Small Interfering/metabolism ; Signal Transduction

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Skocz do pozycji: 12.

Tytuł:: Effects of Kindlin-2 on proliferation and migration of VSMC and integrinβ1 andβ3 activity via FAK-PI3K signaling pathway.
Autorzy:: Wu X; Department of Cardiology, Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Xiangyang, Hubei, P.R. China.
Bian F; Department of Cardiology, Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Xiangyang, Hubei, P.R. China.
Hu H; Department of Cardiology, Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Xiangyang, Hubei, P.R. China.
Zhu T; Department of Cardiology, Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Xiangyang, Hubei, P.R. China.
Li C; Department of Cardiology, Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Xiangyang, Hubei, P.R. China.
Zhou Q; Department of Cardiology, Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Xiangyang, Hubei, P.R. China.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2020 Jun 30; Vol. 15 (6), pp. e0225173. Date of Electronic Publication: 2020 Jun 30 (Print Publication: 2020).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cell Movement*
Signal Transduction*
Focal Adhesion Kinase 1/*metabolism
Integrin beta1/*metabolism
Integrin beta3/*metabolism
Membrane Proteins/*metabolism
Muscle, Smooth, Vascular/*cytology
Neoplasm Proteins/*metabolism
Phosphatidylinositol 3-Kinases/*metabolism
Animals ; Cell Proliferation ; Gene Knockdown Techniques ; Hyperplasia/metabolism ; Hyperplasia/pathology ; Membrane Proteins/genetics ; Neoplasm Proteins/genetics ; Rats

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Skocz do pozycji: 13.

Tytuł:: Overexpression of PODXL/ITGB1 and BCL7B/ITGB1 accurately predicts unfavorable prognosis compared to the TNM staging system in postoperative pancreatic cancer patients.
Autorzy:: Taniuchi K; Department of Gastroenterology and Hepatology, Kochi Medical School, Kochi University, Nankoku, Kochi, Japan.; Department of Endoscopic Diagnostics and Therapeutics, Kochi Medical School, Kochi University, Nankoku, Kochi, Japan.
Furihata M; Department of Pathology, Kochi Medical School, Kochi University, Nankoku, Kochi, Japan.
Naganuma S; Department of Pathology, Kochi Medical School, Kochi University, Nankoku, Kochi, Japan.
Sakaguchi M; Integrated Center for Advanced Medical Technologies, Kochi Medical School, Kochi University, Nankoku, Kochi, Japan.; Cancer Prevention and Control Division, Kanagawa Cancer Center Research Institute, Yokohama, Kanagawa, Japan.
Saibara T; Department of Gastroenterology and Hepatology, Kochi Medical School, Kochi University, Nankoku, Kochi, Japan.; Department of Endoscopic Diagnostics and Therapeutics, Kochi Medical School, Kochi University, Nankoku, Kochi, Japan.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2019 Jun 05; Vol. 14 (6), pp. e0217920. Date of Electronic Publication: 2019 Jun 05 (Print Publication: 2019).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Integrin beta1/*metabolism
Pancreatic Neoplasms/*metabolism
Pancreatic Neoplasms/*pathology
Proteins/*metabolism
Sialoglycoproteins/*metabolism
Adult ; Aged ; Aged, 80 and over ; Female ; Humans ; Kaplan-Meier Estimate ; Male ; Middle Aged ; Multivariate Analysis ; Neoplasm Staging ; Postoperative Period ; Prognosis ; Proportional Hazards Models ; Rho Guanine Nucleotide Exchange Factors/metabolism ; Treatment Outcome ; Tumor Burden

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Skocz do pozycji: 14.

Tytuł:: Transmembrane collagen XVII modulates integrin dependent keratinocyte migration via PI3K/Rac1 signaling.
Autorzy:: Löffek S; Department of Dermatology and Venerology, University Medical Center Freiburg, Freiburg, Germany.
Hurskainen T; Department of Dermatology, Oulu Center for Cell-Matrix Research, University of Oulu, and Clinical Research Center, Oulu University Hospital, Oulu, Finland.
Jackow J; Department of Dermatology and Venerology, University Medical Center Freiburg, Freiburg, Germany.
Sigloch FC; Institute of Molecular Medicine and Cell Research, University of Freiburg, Freiburg, Germany ; Faculty of Biology, University of Freiburg, Freiburg, Germany.
Schilling O; Institute of Molecular Medicine and Cell Research, University of Freiburg, Freiburg, Germany ; Bioss Centre for Biological Studies, University of Freiburg, Freiburg, Germany.
Tasanen K; Department of Dermatology, Oulu Center for Cell-Matrix Research, University of Oulu, and Clinical Research Center, Oulu University Hospital, Oulu, Finland.
Bruckner-Tuderman L; Department of Dermatology and Venerology, University Medical Center Freiburg, Freiburg, Germany ; Freiburg Institute of Advanced Studies, School of Life Sciences - LifeNet, University of Freiburg, Freiburg, Germany.
Franzke CW; Department of Dermatology and Venerology, University Medical Center Freiburg, Freiburg, Germany.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2014 Feb 05; Vol. 9 (2), pp. e87263. Date of Electronic Publication: 2014 Feb 05 (Print Publication: 2014).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Autoantigens/*metabolism
Cell Movement/*physiology
Integrin beta1/*metabolism
Integrin beta4/*metabolism
Keratinocytes/*metabolism
Neuropeptides/*metabolism
Non-Fibrillar Collagens/*metabolism
Phosphatidylinositol 3-Kinases/*metabolism
Signal Transduction/*physiology
rac1 GTP-Binding Protein/*metabolism
Animals ; Autoantigens/genetics ; Carcinoma, Squamous Cell/genetics ; Carcinoma, Squamous Cell/metabolism ; Carcinoma, Squamous Cell/pathology ; Cell Adhesion/physiology ; Cell Adhesion Molecules/genetics ; Cell Adhesion Molecules/metabolism ; Focal Adhesion Kinase 1/genetics ; Focal Adhesion Kinase 1/metabolism ; Integrin beta1/genetics ; Integrin beta4/genetics ; Keratinocytes/cytology ; Mice ; Mice, Knockout ; Neoplasm Invasiveness ; Neuropeptides/genetics ; Non-Fibrillar Collagens/genetics ; Phosphatidylinositol 3-Kinases/genetics ; Pseudopodia/genetics ; Pseudopodia/metabolism ; Skin Neoplasms/genetics ; Skin Neoplasms/metabolism ; Skin Neoplasms/pathology ; Wound Healing/physiology ; rac1 GTP-Binding Protein/genetics ; Kalinin ; Collagen Type XVII

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Skocz do pozycji: 15.

Tytuł:: MicroRNA- 130b suppresses migration and invasion of colorectal cancer cells through downregulation of integrin β1 [corrected].
Autorzy:: Zhao Y; The Key Laboratory of Geriatrics, Beijing Hospital & Beijing Institute of Geriatrics, Ministry of Health, Beijing, China.
Miao G; Department of Surgery, Beijing Hospital, Ministry of Health, Beijing, China.
Li Y; Department of Surgery, Beijing Hospital, Ministry of Health, Beijing, China.
Isaji T; Division of Regulatory Glycobiology, Institute of Molecular Biomembrane and Glycobiology, Tohoku Pharmaceutical University, Sendai, Miyagi, Japan.
Gu J; Division of Regulatory Glycobiology, Institute of Molecular Biomembrane and Glycobiology, Tohoku Pharmaceutical University, Sendai, Miyagi, Japan.
Li J; The Key Laboratory of Geriatrics, Beijing Hospital & Beijing Institute of Geriatrics, Ministry of Health, Beijing, China.
Qi R; The Key Laboratory of Geriatrics, Beijing Hospital & Beijing Institute of Geriatrics, Ministry of Health, Beijing, China.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2014 Feb 03; Vol. 9 (2), pp. e87938. Date of Electronic Publication: 2014 Feb 03 (Print Publication: 2014).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cell Movement*
Cell Proliferation*
Biomarkers, Tumor/*genetics
Colorectal Neoplasms/*pathology
Integrin beta1/*metabolism
MicroRNAs/*genetics
Apoptosis ; Biomarkers, Tumor/metabolism ; Blotting, Western ; Colorectal Neoplasms/genetics ; Colorectal Neoplasms/metabolism ; Female ; Humans ; Immunoenzyme Techniques ; Integrin beta1/genetics ; Male ; Middle Aged ; Neoplasm Invasiveness ; RNA, Messenger/genetics ; Real-Time Polymerase Chain Reaction ; Reverse Transcriptase Polymerase Chain Reaction ; Tumor Cells, Cultured

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Skocz do pozycji: 16.

Tytuł:: β1 integrin signaling maintains human epithelial progenitor cell survival in situ and controls proliferation, apoptosis and migration of their progeny.
Autorzy:: Ernst N; Department of Dermatology, University of Luebeck, Luebeck, Germany.
Yay A; Department of Histology and Embryology, University of Erciyes, Kayseri, Turkey.
Bíró T; DE-MTA ''Lendület'' Cellular Physiology Group, Department of Physiology, University of Debrecen, Debrecen, Hungary.
Tiede S; Institute of Experimental Immunology, Euroimmun AG, Luebeck, Germany.
Humphries M; Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom.
Paus R; Department of Dermatology, University of Luebeck, Luebeck, Germany ; Institute of Inflammation and Repair, University of Manchester, Manchester, United Kingdom.
Kloepper JE; Department of Dermatology, University of Luebeck, Luebeck, Germany.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2013 Dec 27; Vol. 8 (12), pp. e84356. Date of Electronic Publication: 2013 Dec 27 (Print Publication: 2013).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Apoptosis*/drug effects
Cell Movement*/drug effects
Signal Transduction*
Epithelial Cells/*cytology
Integrin beta1/*metabolism
Stem Cells/*cytology
Adult ; Aged ; Azo Compounds/pharmacology ; Cell Proliferation/drug effects ; Cell Survival ; DNA/biosynthesis ; Extracellular Matrix/drug effects ; Extracellular Matrix/metabolism ; Female ; Gene Silencing ; Hair Follicle/cytology ; Humans ; Integrin beta1/genetics ; Keratinocytes/cytology ; Keratinocytes/drug effects ; Ligands ; Middle Aged ; Pyrazoles/pharmacology ; Stem Cells/drug effects ; Stem Cells/metabolism ; Young Adult