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Wyszukujesz frazę ""Intercalating Agents"" wg kryterium: Temat


Tytuł:
Controlling Chiroptical Responses via Chemo-Mechanical Deformation of DNA Origami Structures.
Autorzy:
Kim T; Department of Mechanical Engineering, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, Korea.
Lee C; Institute of Advanced Machines and Design, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, Korea.
Lee JY; Institute of Advanced Machines and Design, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, Korea.
Kim DN; Department of Mechanical Engineering, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, Korea.; Institute of Advanced Machines and Design, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, Korea.; Institute of Engineering Research, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, Korea.
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Źródło:
ACS nano [ACS Nano] 2024 Jan 30; Vol. 18 (4), pp. 3414-3423. Date of Electronic Publication: 2024 Jan 18.
Typ publikacji:
Journal Article
MeSH Terms:
Intercalating Agents*
Metal Nanoparticles*/chemistry
Gold/chemistry ; DNA/chemistry ; Silver/chemistry
Czasopismo naukowe
Tytuł:
cGAS-STING Pathway Activation and Systemic Anti-Tumor Immunity Induction via Photodynamic Nanoparticles with Potent Toxic Platinum DNA Intercalator Against Uveal Melanoma.
Autorzy:
Tao H; Department of Ophthalmology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, 410013, P. R. China.
Tan J; Eye Center of Xiangya Hospital, Central South University, Changsha, Hunan, 410008, P. R. China.; Hunan Key Laboratory of Ophthalmology and National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, P. R. China.
Zhang H; Beijing National Laboratory for Molecular Sciences, Laboratory of Polymer Physics and Chemistry, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, China.; University of Chinese Academy of Sciences, Beijing, 100049, China.
Ren H; Department of Ophthalmology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, 410013, P. R. China.
Cai Z; Department of Ophthalmology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, 410013, P. R. China.
Liu H; Department of Ophthalmology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, 410013, P. R. China.
Wen B; Department of Ophthalmology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, 410013, P. R. China.
Du J; Department of Ophthalmology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, 410013, P. R. China.
Li G; Department of Ophthalmology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, 410013, P. R. China.
Chen S; Department of Spine Surgery, The Third Xiangya Hospital, Central South University, Changsha, Hunan, 410013, P. R. China.
Xiao H; Beijing National Laboratory for Molecular Sciences, Laboratory of Polymer Physics and Chemistry, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, China.; University of Chinese Academy of Sciences, Beijing, 100049, China.
Deng Z; Department of Ophthalmology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, 410013, P. R. China.
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Źródło:
Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2023 Nov; Vol. 10 (33), pp. e2302895. Date of Electronic Publication: 2023 Oct 09.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Intercalating Agents*
Nanoparticles*
Animals ; Mice ; Platinum ; Reactive Oxygen Species ; Nucleotidyltransferases
SCR Disease Name:
Uveal melanoma
Czasopismo naukowe
Tytuł:
Multi intercalators FRET enhanced detection of minute amounts of DNA.
Autorzy:
Ceresa L; Department of Physics and Astronomy, Texas Christian University, Fort Worth, TX, 76109, USA. .
Chavez J; Department of Physics and Astronomy, Texas Christian University, Fort Worth, TX, 76109, USA.
Bus MM; Center for Human Identification, University of North Texas Health Science Center, 3500 Camp Bowie Blvd., Fort Worth, TX, 76107, USA.; Department of Microbiology, Immunology and Genetics, Graduate School of Biomedical Sciences, University of North Texas Health Science Center, 3500 Camp Bowie Blvd., Fort Worth, TX, 76107, USA.
Budowle B; Department of Forensic Medicine, University of Helsinki, Helsinki, Finland.; Forensic Science Institute, Radford University, Radford, VA, USA.
Kitchner E; Department of Physics and Astronomy, Texas Christian University, Fort Worth, TX, 76109, USA.
Kimball J; Department of Physics and Astronomy, Texas Christian University, Fort Worth, TX, 76109, USA.
Gryczynski I; Department of Physics and Astronomy, Texas Christian University, Fort Worth, TX, 76109, USA.
Gryczynski Z; Department of Physics and Astronomy, Texas Christian University, Fort Worth, TX, 76109, USA.
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Źródło:
European biophysics journal : EBJ [Eur Biophys J] 2023 Oct; Vol. 52 (6-7), pp. 593-605. Date of Electronic Publication: 2023 May 04.
Typ publikacji:
Journal Article
MeSH Terms:
Fluorescence Resonance Energy Transfer*/methods
Intercalating Agents*
Humans ; DNA ; Sensitivity and Specificity
Czasopismo naukowe
Tytuł:
Development of an Innovative Colorimetric DNA Biosensor Based on Sugar Measurement.
Autorzy:
El Aamri M; Laboratory of Process Engineering & Environment, Faculty of Sciences and Techniques, Hassan II, University of Casablanca, B.P.146, Mohammedia 28806, Morocco.
Khalki Y; Laboratory of Process Engineering & Environment, Faculty of Sciences and Techniques, Hassan II, University of Casablanca, B.P.146, Mohammedia 28806, Morocco.
Mohammadi H; Laboratory of Process Engineering & Environment, Faculty of Sciences and Techniques, Hassan II, University of Casablanca, B.P.146, Mohammedia 28806, Morocco.
Amine A; Laboratory of Process Engineering & Environment, Faculty of Sciences and Techniques, Hassan II, University of Casablanca, B.P.146, Mohammedia 28806, Morocco.
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Źródło:
Biosensors [Biosensors (Basel)] 2023 Aug 28; Vol. 13 (9). Date of Electronic Publication: 2023 Aug 28.
Typ publikacji:
Journal Article
MeSH Terms:
Colorimetry*
Intercalating Agents*
Reproducibility of Results ; DNA ; Phenol ; Phenols ; RNA
Czasopismo naukowe
Tytuł:
Switching between DNA binding modes with a photo- and redox-active DNA-targeting ligand, part II: the influence of the substitution pattern.
Autorzy:
Dohmen C; Department of Chemistry - Biology, University of Siegen, and Center of Micro- and Nanochemistry and (Bio)Technology (Cμ), Adolf-Reichwein-Str. 2, 57068 Siegen, Germany. .
Ihmels H; Department of Chemistry - Biology, University of Siegen, and Center of Micro- and Nanochemistry and (Bio)Technology (Cμ), Adolf-Reichwein-Str. 2, 57068 Siegen, Germany. .
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Źródło:
Organic & biomolecular chemistry [Org Biomol Chem] 2023 Jul 19; Vol. 21 (28), pp. 5799-5808. Date of Electronic Publication: 2023 Jul 19.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Intercalating Agents*/chemistry
DNA*/chemistry
Ligands ; Oxidation-Reduction
Czasopismo naukowe
Tytuł:
Comparison of Salvianolic Acid A Adsorption by Phenylboronic-Acid-Functionalized Montmorillonites with Different Intercalators.
Autorzy:
Qian J; Zhejiang Provincial TCM Key Laboratory of Chinese Medicine Resource Innovation and Transformation, Zhejiang Provincial International S&T Cooperation Base for Active Ingredients of Medicinal and Edible Plants and Health, School of Pharmaceutical Sciences, Jinhua Academy, Zhejiang Chinese Medical University, Hangzhou 311402, China.
Su J; Zhejiang Provincial TCM Key Laboratory of Chinese Medicine Resource Innovation and Transformation, Zhejiang Provincial International S&T Cooperation Base for Active Ingredients of Medicinal and Edible Plants and Health, School of Pharmaceutical Sciences, Jinhua Academy, Zhejiang Chinese Medical University, Hangzhou 311402, China.
Zeng W; Zhejiang Provincial TCM Key Laboratory of Chinese Medicine Resource Innovation and Transformation, Zhejiang Provincial International S&T Cooperation Base for Active Ingredients of Medicinal and Edible Plants and Health, School of Pharmaceutical Sciences, Jinhua Academy, Zhejiang Chinese Medical University, Hangzhou 311402, China.
Wang Y; Zhejiang Provincial TCM Key Laboratory of Chinese Medicine Resource Innovation and Transformation, Zhejiang Provincial International S&T Cooperation Base for Active Ingredients of Medicinal and Edible Plants and Health, School of Pharmaceutical Sciences, Jinhua Academy, Zhejiang Chinese Medical University, Hangzhou 311402, China.
Hu Y; School of Chemistry and Life Sciences, Suzhou University of Science and Technology, Suzhou 215009, China.
Kai G; Zhejiang Provincial TCM Key Laboratory of Chinese Medicine Resource Innovation and Transformation, Zhejiang Provincial International S&T Cooperation Base for Active Ingredients of Medicinal and Edible Plants and Health, School of Pharmaceutical Sciences, Jinhua Academy, Zhejiang Chinese Medical University, Hangzhou 311402, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Jul 06; Vol. 28 (13). Date of Electronic Publication: 2023 Jul 06.
Typ publikacji:
Journal Article
MeSH Terms:
Bentonite*/chemistry
Intercalating Agents*
Adsorption ; Indicators and Reagents
Czasopismo naukowe
Tytuł:
In silico study of HASDI (high-affinity selective DNA intercalator) as a new agent capable of highly selective recognition of the DNA sequence.
Autorzy:
Zaremba AA; Zabolotny Institute of Microbiology and Virology of NASU, 154 Acad. Zabolotny Str., Kyiv, 03143, Ukraine. .
Zaremba PY; Zabolotny Institute of Microbiology and Virology of NASU, 154 Acad. Zabolotny Str., Kyiv, 03143, Ukraine.
Zahorodnia SD; Zabolotny Institute of Microbiology and Virology of NASU, 154 Acad. Zabolotny Str., Kyiv, 03143, Ukraine.
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Źródło:
Scientific reports [Sci Rep] 2023 Apr 03; Vol. 13 (1), pp. 5395. Date of Electronic Publication: 2023 Apr 03.
Typ publikacji:
Journal Article
MeSH Terms:
Intercalating Agents*/chemistry
DNA*/chemistry
Humans ; Base Sequence ; Molecular Dynamics Simulation ; Nucleotides ; Phenazines ; Nucleic Acid Conformation
Czasopismo naukowe
Tytuł:
Isatin-indoloquinoxaline click adducts with a potential to overcome platinum-based drug-resistance in ovarian cancer.
Autorzy:
Chowdhary S; Department of Chemistry, Guru Nanak Dev University, Amritsar, India.
Raza A; Department of Pharmacology, Penn State Cancer Institute, The Pennsylvania State University College of Medicine, Hershey, PA 17033, USA.
Preeti; Department of Chemistry, Guru Nanak Dev University, Amritsar, India.
Kaur S; Department of Chemistry, Khalsa College, Amritsar, India.
Anand A; Department of Chemistry, Khalsa College, Amritsar, India.
Sharma AK; Department of Pharmacology, Penn State Cancer Institute, The Pennsylvania State University College of Medicine, Hershey, PA 17033, USA. Electronic address: .
Kumar V; Department of Chemistry, Guru Nanak Dev University, Amritsar, India. Electronic address: vipan_.
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Źródło:
Bioorganic chemistry [Bioorg Chem] 2024 Jan; Vol. 142, pp. 106953. Date of Electronic Publication: 2023 Nov 01.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Isatin*/pharmacology
Antineoplastic Agents*/chemistry
Ovarian Neoplasms*/drug therapy
Ovarian Neoplasms*/metabolism
Humans ; Female ; Intercalating Agents/pharmacology ; Intercalating Agents/chemistry ; Cell Line, Tumor ; DNA/metabolism ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł:
Target-regulated photoactivities of CdS/Ni-MOF heterojunction with [Ru(bpy) 2 dppz] intercalator: a bisphenol A photoelectrochemical aptasensor.
Autorzy:
Tanjung AP; College of Geography and Environmental Sciences, Key Laboratory of Watershed Earth Surface Processes and Ecological Security, College of Chemistry and Materials Sciences, Key Laboratory of the Ministry of Education for Advanced Catalysis Materials, Zhejiang Normal University, Jinhua, 321004, China.
Yin K; College of Geography and Environmental Sciences, Key Laboratory of Watershed Earth Surface Processes and Ecological Security, College of Chemistry and Materials Sciences, Key Laboratory of the Ministry of Education for Advanced Catalysis Materials, Zhejiang Normal University, Jinhua, 321004, China.
Zhao L; College of Geography and Environmental Sciences, Key Laboratory of Watershed Earth Surface Processes and Ecological Security, College of Chemistry and Materials Sciences, Key Laboratory of the Ministry of Education for Advanced Catalysis Materials, Zhejiang Normal University, Jinhua, 321004, China.
Wu JZ; College of Geography and Environmental Sciences, Key Laboratory of Watershed Earth Surface Processes and Ecological Security, College of Chemistry and Materials Sciences, Key Laboratory of the Ministry of Education for Advanced Catalysis Materials, Zhejiang Normal University, Jinhua, 321004, China.
Wang AJ; College of Geography and Environmental Sciences, Key Laboratory of Watershed Earth Surface Processes and Ecological Security, College of Chemistry and Materials Sciences, Key Laboratory of the Ministry of Education for Advanced Catalysis Materials, Zhejiang Normal University, Jinhua, 321004, China.
Mei LP; College of Geography and Environmental Sciences, Key Laboratory of Watershed Earth Surface Processes and Ecological Security, College of Chemistry and Materials Sciences, Key Laboratory of the Ministry of Education for Advanced Catalysis Materials, Zhejiang Normal University, Jinhua, 321004, China. .
Song P; College of Geography and Environmental Sciences, Key Laboratory of Watershed Earth Surface Processes and Ecological Security, College of Chemistry and Materials Sciences, Key Laboratory of the Ministry of Education for Advanced Catalysis Materials, Zhejiang Normal University, Jinhua, 321004, China. .; Central Laboratory, Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Jinhua, 321000, China. .
Feng JJ; College of Geography and Environmental Sciences, Key Laboratory of Watershed Earth Surface Processes and Ecological Security, College of Chemistry and Materials Sciences, Key Laboratory of the Ministry of Education for Advanced Catalysis Materials, Zhejiang Normal University, Jinhua, 321004, China. .
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Źródło:
Mikrochimica acta [Mikrochim Acta] 2024 Feb 16; Vol. 191 (3), pp. 139. Date of Electronic Publication: 2024 Feb 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Metal-Organic Frameworks*
Biosensing Techniques*/methods
Phenols*
Child ; Humans ; Intercalating Agents ; Benzhydryl Compounds ; DNA
Czasopismo naukowe
Tytuł:
Supercoiling-dependent DNA binding: quantitative modeling and applications to bulk and single-molecule experiments.
Autorzy:
Kolbeck PJ; Department of Physics and Center for NanoScience, LMU Munich, Amalienstrasse 54, 80799 Munich, Germany.; Soft Condensed Matter and Biophysics, Department of Physics and Debye Institute for Nanomaterials Science, Utrecht University, Princetonplein 1, 3584 CC Utrecht, The Netherlands.
Tišma M; Department of Bionanoscience, Kavli Institute of Nanoscience, Delft University of Technology, 2629 HZ Delft, The Netherlands.
Analikwu BT; Department of Bionanoscience, Kavli Institute of Nanoscience, Delft University of Technology, 2629 HZ Delft, The Netherlands.
Vanderlinden W; Department of Physics and Center for NanoScience, LMU Munich, Amalienstrasse 54, 80799 Munich, Germany.; Soft Condensed Matter and Biophysics, Department of Physics and Debye Institute for Nanomaterials Science, Utrecht University, Princetonplein 1, 3584 CC Utrecht, The Netherlands.
Dekker C; Department of Bionanoscience, Kavli Institute of Nanoscience, Delft University of Technology, 2629 HZ Delft, The Netherlands.
Lipfert J; Department of Physics and Center for NanoScience, LMU Munich, Amalienstrasse 54, 80799 Munich, Germany.; Soft Condensed Matter and Biophysics, Department of Physics and Debye Institute for Nanomaterials Science, Utrecht University, Princetonplein 1, 3584 CC Utrecht, The Netherlands.
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Źródło:
Nucleic acids research [Nucleic Acids Res] 2024 Jan 11; Vol. 52 (1), pp. 59-72.
Typ publikacji:
Journal Article
MeSH Terms:
DNA, Superhelical*
DNA ; Fluorescence ; Intercalating Agents/chemistry ; Plasmids/genetics
Czasopismo naukowe
Tytuł:
Study of nitrogen heterocycles as DNA/HSA binder, topoisomerase inhibitors and toxicological safety.
Autorzy:
Dos Santos JC; Molecular Biology Laboratory, University of Pernambuco (UPE), Multicampi Garanhuns, Garanhuns, PE 55290-000, Brazil.
Alves JEF; Keizo Asami Immunopathology Laboratory (LIKA), Federal University of Pernambuco, Recife, PE, Brazil.
de Azevedo RDS; Molecular Biology Laboratory, University of Pernambuco (UPE), Multicampi Garanhuns, Garanhuns, PE 55290-000, Brazil.
de Lima ML; Molecular Biology Laboratory, University of Pernambuco (UPE), Multicampi Garanhuns, Garanhuns, PE 55290-000, Brazil.
de Oliveira Silva MR; Molecular Biology Laboratory, University of Pernambuco (UPE), Multicampi Garanhuns, Garanhuns, PE 55290-000, Brazil.
da Silva JG; Molecular Biology Laboratory, University of Pernambuco (UPE), Multicampi Garanhuns, Garanhuns, PE 55290-000, Brazil.
da Silva JM; Department of Pharmacy, Laboratory of Synthesis and Vectorization of Molecules, State University of Paraíba (UEPB), Campus Campina Grande, 58429-500, PB, Brazil.
de Carvalho Correia AC; Molecular Biology Laboratory, University of Pernambuco (UPE), Multicampi Garanhuns, Garanhuns, PE 55290-000, Brazil.
do Carmo Alves de Lima M; Chemistry and Therapeutic Innovation Laboratory (LQIT), Department of Antibiotics, Federal University of Pernambuco, Recife, PE, Brazil.
de Oliveira JF; University of International Integration of Afro-Brazilian Lusophony (UNILAB), 62790-970 Redenção, CE, Brazil.
de Moura RO; Department of Pharmacy, Laboratory of Synthesis and Vectorization of Molecules, State University of Paraíba (UEPB), Campus Campina Grande, 58429-500, PB, Brazil.
de Almeida SMV; Molecular Biology Laboratory, University of Pernambuco (UPE), Multicampi Garanhuns, Garanhuns, PE 55290-000, Brazil; Keizo Asami Immunopathology Laboratory (LIKA), Federal University of Pernambuco, Recife, PE, Brazil; Chemistry and Therapeutic Innovation Laboratory (LQIT), Department of Antibiotics, Federal University of Pernambuco, Recife, PE, Brazil. Electronic address: .
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Źródło:
International journal of biological macromolecules [Int J Biol Macromol] 2024 Jan; Vol. 254 (Pt 3), pp. 127651. Date of Electronic Publication: 2023 Nov 08.
Typ publikacji:
Journal Article
MeSH Terms:
Topoisomerase Inhibitors*/pharmacology
Topoisomerase Inhibitors*/chemistry
Antineoplastic Agents*/chemistry
Structure-Activity Relationship ; Molecular Docking Simulation ; DNA/chemistry ; Intercalating Agents/pharmacology ; Acridines/pharmacology ; Acridines/chemistry ; Cell Proliferation ; Drug Screening Assays, Antitumor ; Molecular Structure
Czasopismo naukowe
Tytuł:
Discovery of novel benzimidazole acyclic C-nucleoside DNA intercalators halting breast cancer growth.
Autorzy:
Abd Al Moaty MN; Chemistry Department, Faculty of Science, Alexandria University, Alexandria, Egypt.
El Kilany Y; Chemistry Department, Faculty of Science, Alexandria University, Alexandria, Egypt.
Awad LF; Chemistry Department, Faculty of Science, Alexandria University, Alexandria, Egypt.
Ibrahim NA; Chemistry Department, Faculty of Science, Alexandria University, Alexandria, Egypt.
Abu-Serie MM; Medical Biotechnology Department, Genetic Engineering and Biotechnology Research Institute, City of Scientific Research and Technological Applications (SRTA-City), Alexandria, Egypt.
El-Yazbi A; Department of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt.
Teleb M; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt.
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Źródło:
Archiv der Pharmazie [Arch Pharm (Weinheim)] 2024 Jan; Vol. 357 (1), pp. e2300454. Date of Electronic Publication: 2023 Oct 22.
Typ publikacji:
Journal Article
MeSH Terms:
Breast Neoplasms*/drug therapy
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/chemistry
Humans ; Female ; Intercalating Agents/pharmacology ; Nucleosides/pharmacology ; Structure-Activity Relationship ; Doxorubicin/pharmacology ; DNA ; Benzimidazoles/pharmacology ; Sugars
Czasopismo naukowe
Tytuł:
Targeting the Major Groove of the Palindromic d(GGCGCC) 2 Sequence by Oligopeptide Derivatives of Anthraquinone Intercalators.
Autorzy:
El Hage K; SABNP, Univ Evry, INSERM U1204, Université Paris-Saclay, 91000 Evry, France.
Ribaudo G; Dipartimento di Medicina Molecolare e Traslazionale, Universita degli Studi di Brescia, 25123 Brescia, Italy.
Lagardère L; LCT, UMR7616 CNRS, Sorbonne Université Paris, 75005 Paris, France.
Ongaro A; Dipartimento di Medicina Molecolare e Traslazionale, Universita degli Studi di Brescia, 25123 Brescia, Italy.
Kahn PH; CNRS, 75005 Paris, France.
Demange L; Université Paris Cité, CiTCoM, UMR 8038 CNRS, 75006 Paris, France.
Piquemal JP; LCT, UMR7616 CNRS, Sorbonne Université Paris, 75005 Paris, France.; The University of Texas at Austin, Department of Biomedical Engineering, Austin, Texas 78705, United States.
Zagotto G; Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Via Marzolo, 35131 Padova, Italy.
Gresh N; LCT, UMR7616 CNRS, Sorbonne Université Paris, 75005 Paris, France.
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Źródło:
Journal of chemical information and modeling [J Chem Inf Model] 2022 Dec 26; Vol. 62 (24), pp. 6649-6666. Date of Electronic Publication: 2022 Jul 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Intercalating Agents*/pharmacology
Intercalating Agents*/chemistry
Oligopeptides*
Mitoxantrone/pharmacology ; DNA/chemistry ; Molecular Dynamics Simulation ; Nucleic Acid Conformation
Czasopismo naukowe
Tytuł:
Triazoloquinoxalines-based DNA intercalators-Topo II inhibitors: design, synthesis, docking, ADMET and anti-proliferative evaluations.
Autorzy:
Elwan A; Pharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt.
Sakr H; Pharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt.
El-Helby AA; Pharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt.
El-Morsy A; Pharmaceutical Chemistry Department, College of Pharmacy, The Islamic University, Najaf, Iraq.
Abdelgawad MA; Department of Pharmaceutical Chemistry, College of Pharmacy, Jouf University, Sakaka, Saudi Arabia.
Ghoneim MM; Department of Pharmacy Practice, Faculty of Pharmacy, AlMaarefa University, Ad Diriyah, Saudi Arabia.
El-Sherbiny M; Department of Basic Medical Sciences, College of Medicine, AlMaarefa University, Riyadh, Saudi Arabia.; Department of Anatomy, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
El-Adl K; Pharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt.; Chemistry Department, Faculty of Pharmacy, Heliopolis University for Sustainable Development, Cairo, Egypt.
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Źródło:
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2022 Dec; Vol. 37 (1), pp. 1556-1567.
Typ publikacji:
Journal Article
MeSH Terms:
Intercalating Agents*/pharmacology
Topoisomerase II Inhibitors*/chemistry
Topoisomerase II Inhibitors*/pharmacology
DNA ; DNA Topoisomerases, Type II/metabolism ; Dose-Response Relationship, Drug ; Doxorubicin/pharmacology ; Molecular Docking Simulation ; Molecular Structure ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł:
Hoogsteen triplexes stabilized through ethynyl-linked pyrene-indole synthesized by high-temperature Sonogashira coupling.
Autorzy:
Géci I; Department of Medical and Clinical Biophysics, Faculty of Medicine, P. J. Šafárik University in Košice, Trieda SNP 1, 04011 Košice, Slovakia. .; Department of Physics, Chemistry and Pharmacy, University of Southern Denmark, Campusvej 55, DK-5230, Odense M, Denmark.
Fatthalla MI; Department of Chemistry, Faculty of Science, Helwan University, 11795 Ain Helwan, Cairo, Egypt.; Department of Physics, Chemistry and Pharmacy, University of Southern Denmark, Campusvej 55, DK-5230, Odense M, Denmark.; Universite Paris-Sud, CNRS, Faculte de Pharmacie, 5 rue J.-B. Clement, Chatenay-Malabry, 92296 France.
Heintz M; Department of Physics, Chemistry and Pharmacy, University of Southern Denmark, Campusvej 55, DK-5230, Odense M, Denmark.
Jørgensen PT; Department of Physics, Chemistry and Pharmacy, University of Southern Denmark, Campusvej 55, DK-5230, Odense M, Denmark.
Pedersen EB; Department of Physics, Chemistry and Pharmacy, University of Southern Denmark, Campusvej 55, DK-5230, Odense M, Denmark.
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Źródło:
Organic & biomolecular chemistry [Org Biomol Chem] 2022 Nov 23; Vol. 20 (45), pp. 8873-8884. Date of Electronic Publication: 2022 Nov 23.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Intercalating Agents*/chemistry
Nucleic Acids*/chemistry
Temperature ; Oligonucleotides/chemistry ; Pyrenes/chemistry ; DNA/chemistry ; Indoles ; Nucleic Acid Conformation ; Nucleic Acid Denaturation
Czasopismo naukowe
Tytuł:
Excited-State Dynamics of Proflavine after Intercalation into DNA Duplex.
Autorzy:
Zhou J; State Key Laboratory of Precision Spectroscopy, East China Normal University, Shanghai 200241, China.
Jia Y; Key Laboratory for Advanced Materials, Feringa Nobel Prize Scientist Joint Research Center, Institute of Fine Chemicals, School of Chemistry & Molecular Engineering, East China University of Science and Technology, Shanghai 200237, China.
Wang X; State Key Laboratory of Precision Spectroscopy, East China Normal University, Shanghai 200241, China.
Jia M; State Key Laboratory of Precision Spectroscopy, East China Normal University, Shanghai 200241, China.
Pan H; State Key Laboratory of Precision Spectroscopy, East China Normal University, Shanghai 200241, China.
Sun Z; State Key Laboratory of Precision Spectroscopy, East China Normal University, Shanghai 200241, China.
Chen J; State Key Laboratory of Precision Spectroscopy, East China Normal University, Shanghai 200241, China.; Collaborative Innovation Center of Extreme Optics, Shanxi University, Taiyuan 030006, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2022 Nov 23; Vol. 27 (23). Date of Electronic Publication: 2022 Nov 23.
Typ publikacji:
Journal Article
MeSH Terms:
Proflavine*/chemistry
Intercalating Agents*
DNA/chemistry ; Acridines
Czasopismo naukowe
Tytuł:
Thermal stabilisation of the short DNA duplexes by acridine-4-carboxamide derivatives.
Autorzy:
Kostelansky F; Faculty of Pharmacy in Hradec Králové, Charles University, Ak. Heyrovskeho 1203, Hradec Kralove, 500 05, Czech Republic.
Miletin M; Faculty of Pharmacy in Hradec Králové, Charles University, Ak. Heyrovskeho 1203, Hradec Kralove, 500 05, Czech Republic.
Havlinova Z; Generi Biotech, Machkova 587, Hradec Kralove, 500 11, Czech Republic.
Szotakova B; Generi Biotech, Machkova 587, Hradec Kralove, 500 11, Czech Republic.
Libra A; Generi Biotech, Machkova 587, Hradec Kralove, 500 11, Czech Republic.
Kucera R; Faculty of Pharmacy in Hradec Králové, Charles University, Ak. Heyrovskeho 1203, Hradec Kralove, 500 05, Czech Republic.
Novakova V; Faculty of Pharmacy in Hradec Králové, Charles University, Ak. Heyrovskeho 1203, Hradec Kralove, 500 05, Czech Republic.
Zimcik P; Faculty of Pharmacy in Hradec Králové, Charles University, Ak. Heyrovskeho 1203, Hradec Kralove, 500 05, Czech Republic.
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Źródło:
Nucleic acids research [Nucleic Acids Res] 2022 Oct 14; Vol. 50 (18), pp. 10212-10229.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Acridines*
Intercalating Agents*
Carbon ; DNA/genetics ; DNA/metabolism ; Oligodeoxyribonucleotides
Czasopismo naukowe
Tytuł:
Left versus right: Exploring the effects of chiral threading intercalators using optical tweezers.
Autorzy:
Jabak AA; Department of Physics, Photonics and Optical Engineering, Bridgewater State University, Bridgewater, Massachusetts.
Bryden N; Department of Physics, Photonics and Optical Engineering, Bridgewater State University, Bridgewater, Massachusetts.
Westerlund F; Department of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden.
Lincoln P; Department of Chemistry and Chemical Engineering, Chalmers University of Technology, Gothenburg, Sweden.
McCauley MJ; Department of Physics, Northeastern University, Boston, Massachusetts.
Rouzina I; Department of Chemistry and Biochemistry, The Ohio State University, Columbus, Ohio.
Williams MC; Department of Physics, Northeastern University, Boston, Massachusetts. Electronic address: .
Paramanathan T; Department of Physics, Photonics and Optical Engineering, Bridgewater State University, Bridgewater, Massachusetts. Electronic address: .
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Źródło:
Biophysical journal [Biophys J] 2022 Oct 04; Vol. 121 (19), pp. 3745-3752. Date of Electronic Publication: 2022 Apr 25.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Intercalating Agents*/chemistry
Ruthenium*/chemistry
DNA/chemistry ; Optical Tweezers ; Stereoisomerism
Czasopismo naukowe
Tytuł:
Carboranyl-1,8-naphthalimide intercalators induce lysosomal membrane permeabilization and ferroptosis in cancer cell lines.
Autorzy:
Rykowski S; Institute of Medical Biology, Polish Academy of Sciences, Łódź, Poland.
Gurda-Woźna D; Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Poland.
Fedoruk-Wyszomirska A; Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Poland.
Orlicka-Płocka M; Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Poland.
Kowalczyk A; Department of Molecular Microbiology, Faculty of Biology and Environmental Protection, University of Lodz, Łódź, Poland.
Stączek P; Department of Molecular Microbiology, Faculty of Biology and Environmental Protection, University of Lodz, Łódź, Poland.
Denel-Bobrowska M; Institute of Medical Biology, Polish Academy of Sciences, Łódź, Poland.
Biniek-Antosiak K; Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Poland.
Rypniewski W; Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Poland.
Wyszko E; Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Poland.
Olejniczak AB; Institute of Medical Biology, Polish Academy of Sciences, Łódź, Poland.
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Źródło:
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2023 Dec; Vol. 38 (1), pp. 2171028.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents*/chemistry
Ferroptosis*
Neoplasms*
Intercalating Agents ; Naphthalimides ; Cell Line ; DNA/chemistry ; Lysosomes/metabolism ; Cell Line, Tumor
Czasopismo naukowe
Tytuł:
Investigating the potential anticancer activities of antibiotics as topoisomerase II inhibitors and DNA intercalators: in vitro , molecular docking, molecular dynamics, and SAR studies.
Autorzy:
Farouk F; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Ahram Canadian University, Giza, Egypt.
Elmaaty AA; Department of Medicinal Chemistry, Faculty of Pharmacy, Port Said University, Port Said, Egypt.
Elkamhawy A; BK21 FOUR Team and Integrated Research Institute for Drug Development, College of Pharmacy, Dongguk University-Seoul, Goyang, Republic of Korea.; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.
Tawfik HO; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Tanta University, Tanta, Egypt.
Alnajjar R; Department of Chemistry, Faculty of Science, University of Benghazi, Benghazi, Libya.; PharmD, Faculty of Pharmacy, Libyan International Medical University, Benghazi, Libya.; Department of Chemistry, University of Cape Town, Rondebosch, South Africa.
Abourehab MAS; Department of Pharmaceutics, Faculty of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia.
Saleh MA; Department of Clinical Sciences, College of Medicine, University of Sharjah, Sharjah, the United Arab Emirates.; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.
Eldehna WM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, Egypt.; School of Biotechnology, Badr University in Cairo, Badr City, Egypt.
Al-Karmalawy AA; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Ahram Canadian University, Giza, Egypt.
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Źródło:
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2023 Dec; Vol. 38 (1), pp. 2171029.
Typ publikacji:
Journal Article
MeSH Terms:
Topoisomerase II Inhibitors*/pharmacology
Topoisomerase II Inhibitors*/chemistry
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/chemistry
Humans ; Molecular Docking Simulation ; Molecular Structure ; Intercalating Agents/pharmacology ; Anti-Bacterial Agents/pharmacology ; Structure-Activity Relationship ; Molecular Dynamics Simulation ; Cell Line, Tumor ; DNA ; DNA Topoisomerases, Type II/metabolism ; Drug Screening Assays, Antitumor
Czasopismo naukowe

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