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Wyszukujesz frazę ""Interferon Type I"" wg kryterium: Temat


Tytuł:
MicroRNA-218-5p-Ddx41 axis restrains microglia-mediated neuroinflammation through downregulating type I interferon response in a mouse model of Parkinson's disease.
Autorzy:
Wang D; Department of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Gao H; Department of Neurology, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
Qin Q; Department of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Li J; Department of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Zhao J; Department of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Qu Y; Department of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Li J; Department of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Xiong Y; Department of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Min Z; Department of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Mao Z; Department of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. .
Xue Z; Department of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. .; Department of General Practice, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. .
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Źródło:
Journal of translational medicine [J Transl Med] 2024 Jan 16; Vol. 22 (1), pp. 63. Date of Electronic Publication: 2024 Jan 16.
Typ publikacji:
Journal Article
MeSH Terms:
MicroRNAs*/genetics
MicroRNAs*/metabolism
Parkinson Disease*/genetics
Parkinson Disease*/pathology
Interferon Type I*/adverse effects
Interferon Type I*/metabolism
Neuroblastoma*/metabolism
Neuroblastoma*/pathology
Humans ; Mice ; Animals ; Microglia/metabolism ; Neuroinflammatory Diseases ; Dopaminergic Neurons/metabolism ; Inflammation/pathology ; Dopamine/adverse effects ; Dopamine/metabolism ; Luciferases/metabolism ; Mice, Inbred C57BL
Czasopismo naukowe
Tytuł:
Microtubule disruption synergizes with STING signaling to show potent and broad-spectrum antiviral activity.
Autorzy:
Han J; State Key Laboratory of Membrane Biology, School of Pharmaceutical Sciences, Tsinghua University, Beijing, China.; Tsinghua-Peking Center for Life Sciences, Beijing, China.
Wang Z; State Key Laboratory of Membrane Biology, School of Pharmaceutical Sciences, Tsinghua University, Beijing, China.; Tsinghua-Peking Center for Life Sciences, Beijing, China.
Han F; State Key Laboratory of Membrane Biology, School of Pharmaceutical Sciences, Tsinghua University, Beijing, China.; Tsinghua-Peking Center for Life Sciences, Beijing, China.
Peng B; Department of Microbiology Laboratory, Shenzhen Center for Disease Control and Prevention, Shenzhen, China.
Du J; State Key Laboratory of Membrane Biology, School of Pharmaceutical Sciences, Tsinghua University, Beijing, China.; MOE Key Laboratory of Bioorganic Phosphorus Chemistry &Chemical Biology, Tsinghua University Beijing, China.
Zhang C; State Key Laboratory of Membrane Biology, School of Pharmaceutical Sciences, Tsinghua University, Beijing, China.; Tsinghua-Peking Center for Life Sciences, Beijing, China.
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Źródło:
PLoS pathogens [PLoS Pathog] 2024 Feb 26; Vol. 20 (2), pp. e1012048. Date of Electronic Publication: 2024 Feb 26 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Membrane Proteins*/genetics
Interferon Type I*/pharmacology
Immunity, Innate ; Signal Transduction ; Cytokines
Czasopismo naukowe
Tytuł:
Type I IFN in Glomerular Disease: Scarring beyond the STING.
Autorzy:
Jimenez-Uribe AP; Department of Internal Medicine, Division of Nephrology, Rush University Medical Center, Chicago, IL 60612, USA.
Mangos S; Department of Internal Medicine, Division of Nephrology, Rush University Medical Center, Chicago, IL 60612, USA.
Hahm E; Department of Internal Medicine, Division of Nephrology, Rush University Medical Center, Chicago, IL 60612, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 21; Vol. 25 (5). Date of Electronic Publication: 2024 Feb 21.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Interferon Type I*/metabolism
Virus Diseases*
Humans ; Immunity, Innate ; Signal Transduction/physiology ; Cicatrix ; Toll-Like Receptors ; Inflammation
Czasopismo naukowe
Tytuł:
SARS-CoV-2 ORF7a Mutation Found in BF.5 and BF.7 Sublineages Impacts Its Functions.
Autorzy:
Timilsina U; Department of Microbiology and Immunology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY 14203, USA.
Ivey EB; Department of Microbiology and Immunology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY 14203, USA.
Duffy S; Department of Microbiology and Immunology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY 14203, USA.
Plianchaisuk A; Division of Systems Virology, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo, Tokyo 108-8369, Japan.
The Genotype To Phenotype Japan G P-Japan Consortium
Ito J; Division of Systems Virology, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo, Tokyo 108-8369, Japan.
Sato K; Division of Systems Virology, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo, Tokyo 108-8369, Japan.; International Research Center for Infectious Diseases, The Institute of Medical Science, The University of Tokyo, Tokyo 108-8369, Japan.; Graduate School of Medicine, The University of Tokyo, Tokyo 113-8654, Japan.; Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa 277-8581, Japan.; International Vaccine Design Center, The Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan.; Collaboration Unit for Infection, Joint Research Center for Human Retrovirus Infection, Kumamoto University, Kumamoto 860-0862, Japan.; CREST, Japan Science and Technology Agency, Kawaguchi 332-0012, Japan.
Stavrou S; Department of Microbiology and Immunology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY 14203, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 16; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 16.
Typ publikacji:
Journal Article
MeSH Terms:
COVID-19*/genetics
Interferon Type I*/metabolism
Humans ; SARS-CoV-2/genetics ; SARS-CoV-2/metabolism ; Mutation ; China
Czasopismo naukowe
Tytuł:
Translational Control of Alphavirus-Host Interactions: Implications in Viral Evolution, Tropism and Antiviral Response.
Autorzy:
Ventoso I; Centro de Biología Molecular 'Severo Ochoa' (CSIC-UAM) and Departamento de Biología Molecular, Universidad Autónoma de Madrid (UAM), 28049 Madrid, Spain.
Berlanga JJ; Centro de Biología Molecular 'Severo Ochoa' (CSIC-UAM) and Departamento de Biología Molecular, Universidad Autónoma de Madrid (UAM), 28049 Madrid, Spain.
Toribio R; Centro de Biotecnología y Genómica de Plantas, Universidad Politécnica de Madrid-Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (UPM-INIA), 28049 Madrid, Spain.
Díaz-López I; MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK.
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Źródło:
Viruses [Viruses] 2024 Jan 30; Vol. 16 (2). Date of Electronic Publication: 2024 Jan 30.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Alphavirus*/physiology
Interferon Type I*/genetics
Animals ; Cell Line ; Vertebrates ; Tropism ; Antiviral Agents/pharmacology ; Virus Replication
Czasopismo naukowe
Tytuł:
Antiviral Defence Mechanisms during Early Mammalian Development.
Autorzy:
Mueller F; Institute of Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, King's Buildings, Charlotte Auerbach Road, Edinburgh EH9 3FL, UK.; Centre for Virus Research, MRC-University of Glasgow, Garscube Campus, 464 Bearsden Road, Glasgow G61 1QH, UK.
Witteveldt J; Institute of Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, King's Buildings, Charlotte Auerbach Road, Edinburgh EH9 3FL, UK.
Macias S; Institute of Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, King's Buildings, Charlotte Auerbach Road, Edinburgh EH9 3FL, UK.
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Źródło:
Viruses [Viruses] 2024 Jan 24; Vol. 16 (2). Date of Electronic Publication: 2024 Jan 24.
Typ publikacji:
Meta-Analysis; Journal Article; Review
MeSH Terms:
Interferon Type I*
Viruses*
Animals ; Mammals ; Antiviral Agents ; Immunity, Innate
Czasopismo naukowe
Tytuł:
A bibliometric analysis of m6A methylation in viral infection from 2000 to 2022.
Autorzy:
Tao X; Guangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health, Guangxi Medical University, Nanning, Guangxi, China.; China (Guangxi) - ASEAN Joint Laboratory of Emerging Infectious Diseases, Guangxi Medical University, Nanning, Guangxi, China.
Wang G; Guangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health, Guangxi Medical University, Nanning, Guangxi, China.; China (Guangxi) - ASEAN Joint Laboratory of Emerging Infectious Diseases, Guangxi Medical University, Nanning, Guangxi, China.
Wei W; Guangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health, Guangxi Medical University, Nanning, Guangxi, China.; China (Guangxi) - ASEAN Joint Laboratory of Emerging Infectious Diseases, Guangxi Medical University, Nanning, Guangxi, China.; Biosafety Level -3 Laboratory, Life Sciences Institute, Guangxi Medical University, Nanning, Guangxi, China.
Su J; Guangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health, Guangxi Medical University, Nanning, Guangxi, China.; China (Guangxi) - ASEAN Joint Laboratory of Emerging Infectious Diseases, Guangxi Medical University, Nanning, Guangxi, China.; Biosafety Level -3 Laboratory, Life Sciences Institute, Guangxi Medical University, Nanning, Guangxi, China.
Chen X; Guangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health, Guangxi Medical University, Nanning, Guangxi, China.; China (Guangxi) - ASEAN Joint Laboratory of Emerging Infectious Diseases, Guangxi Medical University, Nanning, Guangxi, China.
Shi M; Guangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health, Guangxi Medical University, Nanning, Guangxi, China.; China (Guangxi) - ASEAN Joint Laboratory of Emerging Infectious Diseases, Guangxi Medical University, Nanning, Guangxi, China.
Liao Y; Guangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health, Guangxi Medical University, Nanning, Guangxi, China.; China (Guangxi) - ASEAN Joint Laboratory of Emerging Infectious Diseases, Guangxi Medical University, Nanning, Guangxi, China.
Qin T; Guangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health, Guangxi Medical University, Nanning, Guangxi, China.; China (Guangxi) - ASEAN Joint Laboratory of Emerging Infectious Diseases, Guangxi Medical University, Nanning, Guangxi, China.
Wu Y; Guangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health, Guangxi Medical University, Nanning, Guangxi, China.; China (Guangxi) - ASEAN Joint Laboratory of Emerging Infectious Diseases, Guangxi Medical University, Nanning, Guangxi, China.
Lu B; Guangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health, Guangxi Medical University, Nanning, Guangxi, China.; China (Guangxi) - ASEAN Joint Laboratory of Emerging Infectious Diseases, Guangxi Medical University, Nanning, Guangxi, China.
Liang H; Guangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health, Guangxi Medical University, Nanning, Guangxi, China. .; China (Guangxi) - ASEAN Joint Laboratory of Emerging Infectious Diseases, Guangxi Medical University, Nanning, Guangxi, China. .; Biosafety Level -3 Laboratory, Life Sciences Institute, Guangxi Medical University, Nanning, Guangxi, China. .
Ye L; Guangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health, Guangxi Medical University, Nanning, Guangxi, China. .; China (Guangxi) - ASEAN Joint Laboratory of Emerging Infectious Diseases, Guangxi Medical University, Nanning, Guangxi, China. .
Jiang J; Guangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health, Guangxi Medical University, Nanning, Guangxi, China. .; China (Guangxi) - ASEAN Joint Laboratory of Emerging Infectious Diseases, Guangxi Medical University, Nanning, Guangxi, China. .; Biosafety Level -3 Laboratory, Life Sciences Institute, Guangxi Medical University, Nanning, Guangxi, China. .
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Źródło:
Virology journal [Virol J] 2024 Jan 18; Vol. 21 (1), pp. 20. Date of Electronic Publication: 2024 Jan 18.
Typ publikacji:
Journal Article
MeSH Terms:
Virus Diseases*
Interferon Type I*
Neoplasms*
Adenine/*analogs & derivatives
Humans ; Bibliometrics ; Methylation ; Methyltransferases
Czasopismo naukowe
Tytuł:
A rare manifestation of STING-associated vasculopathy with onset in infancy: a case report.
Autorzy:
Weidler S; Department of Pediatrics, Medizinische Fakultät Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany. .
Koss S; Department of Pediatrics, Medizinische Fakultät Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Wolf C; Department of Pediatrics, Medizinische Fakultät Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Lucas N; Department of Pediatrics, Medizinische Fakultät Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Brunner J; Department of Pediatrics, Innsbruck Medical University, Innsbruck, Austria.; Faculty of Medicine and Dentistry, Danube Private University, 3500, Krems, Austria.
Lee-Kirsch MA; Department of Pediatrics, Medizinische Fakultät Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
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Źródło:
Pediatric rheumatology online journal [Pediatr Rheumatol Online J] 2024 Jan 04; Vol. 22 (1), pp. 9. Date of Electronic Publication: 2024 Jan 04.
Typ publikacji:
Case Reports; Journal Article
MeSH Terms:
Immunologic Deficiency Syndromes*
Interferon Type I*/genetics
Vascular Diseases*/genetics
Child, Preschool ; Humans ; Inflammation/genetics ; Lung ; Mutation ; Male ; Female
Czasopismo naukowe
Tytuł:
Transfer of cGAMP from neuron to microglia activates microglial type I interferon responses after subarachnoid hemorrhage.
Autorzy:
Chang H; Department of Neurosurgery, Jiangsu Province Hospital and Nanjing Medical University First Affiliated Hospital, Nanjing, 210029, Jiangsu, China.
Li Z; Department of Neurosurgery, Jiangsu Province Hospital and Nanjing Medical University First Affiliated Hospital, Nanjing, 210029, Jiangsu, China.
Zhang W; Department of Ophthalmology, Third Medical Center of Chinese, PLA General Hospital, Beijing, 100000, China.
Lin C; Department of Neurosurgery, Jiangsu Province Hospital and Nanjing Medical University First Affiliated Hospital, Nanjing, 210029, Jiangsu, China.
Shen Y; Department of Neurosurgery, Jiangsu Province Hospital and Nanjing Medical University First Affiliated Hospital, Nanjing, 210029, Jiangsu, China.
Zhang G; Department of Neurosurgery, Jiangsu Province Hospital and Nanjing Medical University First Affiliated Hospital, Nanjing, 210029, Jiangsu, China.
Mao L; Department of Neurosurgery, Jiangsu Province Hospital and Nanjing Medical University First Affiliated Hospital, Nanjing, 210029, Jiangsu, China.
Ma C; Department of Neurosurgery, Jiangsu Province Hospital and Nanjing Medical University First Affiliated Hospital, Nanjing, 210029, Jiangsu, China.
Liu N; Department of Neurosurgery, Jiangsu Province Hospital and Nanjing Medical University First Affiliated Hospital, Nanjing, 210029, Jiangsu, China. .
Lu H; Department of Neurosurgery, Jiangsu Province Hospital and Nanjing Medical University First Affiliated Hospital, Nanjing, 210029, Jiangsu, China. .
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Źródło:
Cell communication and signaling : CCS [Cell Commun Signal] 2024 Jan 02; Vol. 22 (1), pp. 3. Date of Electronic Publication: 2024 Jan 02.
Typ publikacji:
Video-Audio Media; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Interferon Type I*
Subarachnoid Hemorrhage*/complications
Subarachnoid Hemorrhage*/drug therapy
Humans ; Microglia ; Neuroinflammatory Diseases ; Nucleotidyltransferases/genetics ; DNA, Mitochondrial ; Neurons
Czasopismo naukowe
Tytuł:
ISGF3 and STAT2/IRF9 Control Basal and IFN-Induced Transcription through Genome-Wide Binding of Phosphorylated and Unphosphorylated Complexes to Common ISRE-Containing ISGs.
Autorzy:
Nowicka H; Human Molecular Genetics Research Unit, Faculty of Biology, Institute of Molecular Biology and Biotechnology, Adam Mickiewicz University, 61-614 Poznan, Poland.
Sekrecka A; Human Molecular Genetics Research Unit, Faculty of Biology, Institute of Molecular Biology and Biotechnology, Adam Mickiewicz University, 61-614 Poznan, Poland.
Blaszczyk K; Human Molecular Genetics Research Unit, Faculty of Biology, Institute of Molecular Biology and Biotechnology, Adam Mickiewicz University, 61-614 Poznan, Poland.
Kluzek K; Human Molecular Genetics Research Unit, Faculty of Biology, Institute of Molecular Biology and Biotechnology, Adam Mickiewicz University, 61-614 Poznan, Poland.
Chang CY; Graduate Institute of Immunology, National Taiwan University College of Medicine, Taipei 100, Taiwan.
Wesoly J; Laboratory of High Throughput Technologies, Faculty of Biology, Adam Mickiewicz University, 61-614 Poznan, Poland.
Lee CK; Graduate Institute of Immunology, National Taiwan University College of Medicine, Taipei 100, Taiwan.
Bluyssen HAR; Human Molecular Genetics Research Unit, Faculty of Biology, Institute of Molecular Biology and Biotechnology, Adam Mickiewicz University, 61-614 Poznan, Poland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Dec 18; Vol. 24 (24). Date of Electronic Publication: 2023 Dec 18.
Typ publikacji:
Journal Article
MeSH Terms:
Interferon Type I*/metabolism
Interleukin-1 Receptor-Like 1 Protein*/metabolism
Interferon-Stimulated Gene Factor 3*/metabolism
STAT2 Transcription Factor*/metabolism
Antiviral Agents/pharmacology ; DNA/pharmacology ; Immunoglobulins/metabolism ; Signal Transduction ; STAT1 Transcription Factor/metabolism ; Humans
Czasopismo naukowe
Tytuł:
Transcriptomic Changes in Response to Form of Selenium on the Interferon-Tau Signaling Mechanism in the Caruncular Tissue of Beef Heifers at Maternal Recognition of Pregnancy.
Autorzy:
Carr SN; Department of Animal and Food Sciences, University of Kentucky, Lexington, KY 40546, USA.
Crites BR; Department of Animal and Food Sciences, University of Kentucky, Lexington, KY 40546, USA.
Shinde H; Department of Animal and Food Sciences, University of Kentucky, Lexington, KY 40546, USA.
Bridges PJ; Department of Animal and Food Sciences, University of Kentucky, Lexington, KY 40546, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Dec 10; Vol. 24 (24). Date of Electronic Publication: 2023 Dec 10.
Typ publikacji:
Journal Article
MeSH Terms:
Selenium*/pharmacology
Interferon Type I*/genetics
Interferon Type I*/pharmacology
Pregnancy ; Cattle ; Animals ; Female ; Dietary Supplements ; Progesterone/pharmacology ; Gene Expression Profiling ; Endometrium
Czasopismo naukowe
Tytuł:
Mechanism and therapeutic potential of targeting cGAS-STING signaling in neurological disorders.
Autorzy:
Huang Y; Helen and Robert Appel Alzheimer Disease Research Institute, Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY, USA.; Weill Cornell Graduate School of Medical Sciences, Weill Cornell Medicine, New York, NY, USA.
Liu B; Helen and Robert Appel Alzheimer Disease Research Institute, Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY, USA.; Weill Cornell Graduate School of Medical Sciences, Weill Cornell Medicine, New York, NY, USA.
Sinha SC; Helen and Robert Appel Alzheimer Disease Research Institute, Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY, USA.
Amin S; Helen and Robert Appel Alzheimer Disease Research Institute, Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY, USA.
Gan L; Helen and Robert Appel Alzheimer Disease Research Institute, Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY, USA. .; Weill Cornell Graduate School of Medical Sciences, Weill Cornell Medicine, New York, NY, USA. .
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Źródło:
Molecular neurodegeneration [Mol Neurodegener] 2023 Nov 08; Vol. 18 (1), pp. 79. Date of Electronic Publication: 2023 Nov 08.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Interferon Type I*/genetics
Interferon Type I*/metabolism
Nervous System Diseases*
Humans ; Signal Transduction/physiology ; Nucleotidyltransferases/genetics ; Nucleotidyltransferases/metabolism ; DNA/metabolism
Czasopismo naukowe
Tytuł:
Bacillus amyloliquefaciens B10 Alleviates the Immunosuppressive Effects of Deoxynivalenol and Porcine Circovirus Type 2 Infection.
Autorzy:
Xiao H; Joint Research Center for Foodborne Functional Factors and Green Preparation, School of Food and Biological Engineering, Engineering Research Center of Bio-Process, Ministry of Education, Hefei University of Technology, Hefei 230009, China.; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China.; Department of Chemistry, Faculty of Science, University of Hradec Kralove, 50003 Hradec Kralove, Czech Republic.
Qin Z; Joint Research Center for Foodborne Functional Factors and Green Preparation, School of Food and Biological Engineering, Engineering Research Center of Bio-Process, Ministry of Education, Hefei University of Technology, Hefei 230009, China.; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China.; Department of Chemistry, Faculty of Science, University of Hradec Kralove, 50003 Hradec Kralove, Czech Republic.
Xu B; Joint Research Center for Foodborne Functional Factors and Green Preparation, School of Food and Biological Engineering, Engineering Research Center of Bio-Process, Ministry of Education, Hefei University of Technology, Hefei 230009, China.
Long M; Key Laboratory of Zoonosis of Liaoning Province, College of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang 110866, China.
Wu Q; Department of Chemistry, Faculty of Science, University of Hradec Kralove, 50003 Hradec Kralove, Czech Republic.; College of Life Science, Yangtze University, Jingzhou 434025, China.
Guo X; Joint Research Center for Foodborne Functional Factors and Green Preparation, School of Food and Biological Engineering, Engineering Research Center of Bio-Process, Ministry of Education, Hefei University of Technology, Hefei 230009, China.; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China.; Department of Chemistry, Faculty of Science, University of Hradec Kralove, 50003 Hradec Kralove, Czech Republic.
Zhang H; Joint Research Center for Foodborne Functional Factors and Green Preparation, School of Food and Biological Engineering, Engineering Research Center of Bio-Process, Ministry of Education, Hefei University of Technology, Hefei 230009, China.; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China.; Department of Chemistry, Faculty of Science, University of Hradec Kralove, 50003 Hradec Kralove, Czech Republic.
Li Z; Joint Research Center for Foodborne Functional Factors and Green Preparation, School of Food and Biological Engineering, Engineering Research Center of Bio-Process, Ministry of Education, Hefei University of Technology, Hefei 230009, China.; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China.; Department of Chemistry, Faculty of Science, University of Hradec Kralove, 50003 Hradec Kralove, Czech Republic.
Wu W; Joint Research Center for Foodborne Functional Factors and Green Preparation, School of Food and Biological Engineering, Engineering Research Center of Bio-Process, Ministry of Education, Hefei University of Technology, Hefei 230009, China.; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China.; Department of Chemistry, Faculty of Science, University of Hradec Kralove, 50003 Hradec Kralove, Czech Republic.
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Źródło:
Toxins [Toxins (Basel)] 2023 Dec 27; Vol. 16 (1). Date of Electronic Publication: 2023 Dec 27.
Typ publikacji:
Journal Article
MeSH Terms:
Bacillus amyloliquefaciens*
Circovirus*
Interferon Type I*
Mycotoxins*
Trichothecenes*
Animals ; Swine ; Crops, Agricultural ; Nucleotidyltransferases ; Antiviral Agents
Czasopismo naukowe
Tytuł:
The Impact of Innate Components on Viral Pathogenesis in the Neurotropic Coronavirus Encephalomyelitis Mouse Model.
Autorzy:
Boylan BT; Department of Neurosciences, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44196, USA.; Department of Pathology, Case Western Reserve University, Cleveland, OH 44106, USA.
Hwang M; Department of Neurosciences, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44196, USA.; Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA.
Bergmann CC; Department of Neurosciences, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44196, USA.; Department of Pathology, Case Western Reserve University, Cleveland, OH 44106, USA.; Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA.; Department of Biological, Geological and Environmental Sciences, Cleveland State University, Cleveland, OH 44115, USA.; School of Biological Sciences, Kent State University, Kent, OH 44242, USA.
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Źródło:
Viruses [Viruses] 2023 Dec 09; Vol. 15 (12). Date of Electronic Publication: 2023 Dec 09.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Coronavirus*
Encephalomyelitis*
Interferon Type I*
Coronavirus Infections*
Mice ; Animals ; Central Nervous System ; Immunity, Innate
Czasopismo naukowe
Tytuł:
A bispecific Clec9A-PD-L1 targeted type I interferon profoundly reshapes the tumor microenvironment towards an antitumor state.
Autorzy:
Van Lint S; Center for Medical Biotechnology, VIB & Department of Biomolecular Medicine, Ghent University, Ghent, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, Belgium.
Van Parys A; Center for Medical Biotechnology, VIB & Department of Biomolecular Medicine, Ghent University, Ghent, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, Belgium.; Present Affiliation: Orionis Biosciences, Ghent, Belgium.
Van Den Eeckhout B; Center for Medical Biotechnology, VIB & Department of Biomolecular Medicine, Ghent University, Ghent, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, Belgium.
Vandamme N; Cancer Research Institute Ghent (CRIG), Ghent, Belgium.; VIB Single Cell Core, VIB, Ghent-Leuven, Belgium.; Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium.
Plaisance S; VIB Nucleomics Core, Leuven, Belgium.
Verhee A; Center for Medical Biotechnology, VIB & Department of Biomolecular Medicine, Ghent University, Ghent, Belgium.
Catteeuw D; Center for Medical Biotechnology, VIB & Department of Biomolecular Medicine, Ghent University, Ghent, Belgium.
Rogge E; Center for Medical Biotechnology, VIB & Department of Biomolecular Medicine, Ghent University, Ghent, Belgium.; Present Affiliation: Orionis Biosciences, Ghent, Belgium.
De Geest J; Center for Medical Biotechnology, VIB & Department of Biomolecular Medicine, Ghent University, Ghent, Belgium.; Present Affiliation: Orionis Biosciences, Ghent, Belgium.
Vanderroost N; Center for Medical Biotechnology, VIB & Department of Biomolecular Medicine, Ghent University, Ghent, Belgium.
Roels J; VIB Single Cell Core, VIB, Ghent-Leuven, Belgium.; Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium.
Saeys Y; Data Mining and Modelling for Biomedicine, VIB & Center for inflammation research, Ghent University, Ghent, Belgium.; Department of Applied Mathematics, Computer Science and Statistics, Faculty of Science, Ghent University, Ghent, Belgium.
Uzé G; IRMB, University Montpellier, INSERM, CNRS, Montpellier, France.
Kley N; Orionis Biosciences, Ghent, Belgium.; Orionis Biosciences, Boston, USA.
Cauwels A; Center for Medical Biotechnology, VIB & Department of Biomolecular Medicine, Ghent University, Ghent, Belgium.; Present Affiliation: Orionis Biosciences, Ghent, Belgium.
Tavernier J; Center for Medical Biotechnology, VIB & Department of Biomolecular Medicine, Ghent University, Ghent, Belgium. .; Cancer Research Institute Ghent (CRIG), Ghent, Belgium. .; Orionis Biosciences, Ghent, Belgium. .; Orionis Biosciences, Boston, USA. .
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Źródło:
Molecular cancer [Mol Cancer] 2023 Nov 29; Vol. 22 (1), pp. 191. Date of Electronic Publication: 2023 Nov 29.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Interferon Type I*/metabolism
Neoplasms*/metabolism
Humans ; CD8-Positive T-Lymphocytes ; Tumor Microenvironment ; B7-H1 Antigen/metabolism ; Immunotherapy ; Cell Line, Tumor
Czasopismo naukowe
Tytuł:
Human Metapneumovirus-Induced Host microRNA Expression Impairs the Interferon Response in Macrophages and Epithelial Cells.
Autorzy:
Martínez-Espinoza I; Department of Pathobiological Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA 70803, USA.
Bungwon AD; Department of Pathobiological Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA 70803, USA.
Guerrero-Plata A; Department of Pathobiological Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA 70803, USA.
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Źródło:
Viruses [Viruses] 2023 Nov 18; Vol. 15 (11). Date of Electronic Publication: 2023 Nov 18.
Typ publikacji:
Journal Article
MeSH Terms:
Metapneumovirus*
Paramyxoviridae Infections*
MicroRNAs*/genetics
MicroRNAs*/metabolism
Interferon Type I*
Humans ; Epithelial Cells ; Macrophages/metabolism
Czasopismo naukowe
Tytuł:
SARS-CoV-2 Nsp8 suppresses MDA5 antiviral immune responses by impairing TRIM4-mediated K63-linked polyubiquitination.
Autorzy:
Zhang X; Institute of Human Virology, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, Guangdong, China.
Yang Z; Institute of Human Virology, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, Guangdong, China.
Pan T; Center for Infection and Immunity Studies, School of Medicine, Sun Yat-Sen University, Shenzhen, Guangdong, China.
Sun Q; Institute of Human Virology, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, Guangdong, China.
Chen Q; Institute of Human Virology, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, Guangdong, China.
Wang PH; Key Laboratory for Experimental Teratology of Ministry of Education and Advanced Medical Research Institute, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.
Li X; College of Clinical Medicine, Hubei University of Chinese Medicine, Wuhan, Hubei, China.
Kuang E; Institute of Human Virology, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, Guangdong, China.; Key Laboratory of Tropical Disease Control (Sun Yat-Sen University), Ministry of Education, Guangzhou, Guangdong, China.
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Źródło:
PLoS pathogens [PLoS Pathog] 2023 Nov 13; Vol. 19 (11), pp. e1011792. Date of Electronic Publication: 2023 Nov 13 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
COVID-19*/genetics
Interferon Type I*/metabolism
SARS-CoV-2*/metabolism
Humans ; Immunity, Innate ; Interferon-Induced Helicase, IFIH1/genetics ; Interferon-Induced Helicase, IFIH1/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł:
The common H232 STING allele shows impaired activities in DNA sensing, susceptibility to viral infection, and in monocyte cell function, while the HAQ variant possesses wild-type properties.
Autorzy:
Froechlich G; Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli Federico II, Via Pansini 5, 80131, Napoli, NA, Italy.; CEINGE Biotecnologie Avanzate Franco Salvatore S.C.aR.L., Via Gaetano Salvatore 486, 80145, Naples, Italy.
Finizio A; Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli Federico II, Via Pansini 5, 80131, Napoli, NA, Italy.; CEINGE Biotecnologie Avanzate Franco Salvatore S.C.aR.L., Via Gaetano Salvatore 486, 80145, Naples, Italy.
Napolano A; Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli Federico II, Via Pansini 5, 80131, Napoli, NA, Italy.; CEINGE Biotecnologie Avanzate Franco Salvatore S.C.aR.L., Via Gaetano Salvatore 486, 80145, Naples, Italy.
Amiranda S; Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli Federico II, Via Pansini 5, 80131, Napoli, NA, Italy.; CEINGE Biotecnologie Avanzate Franco Salvatore S.C.aR.L., Via Gaetano Salvatore 486, 80145, Naples, Italy.
De Chiara A; Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli Federico II, Via Pansini 5, 80131, Napoli, NA, Italy.; CEINGE Biotecnologie Avanzate Franco Salvatore S.C.aR.L., Via Gaetano Salvatore 486, 80145, Naples, Italy.
Pagano P; Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli Federico II, Via Pansini 5, 80131, Napoli, NA, Italy.; CEINGE Biotecnologie Avanzate Franco Salvatore S.C.aR.L., Via Gaetano Salvatore 486, 80145, Naples, Italy.
Mallardo M; Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli Federico II, Via Pansini 5, 80131, Napoli, NA, Italy.
Leoni G; Nouscom S.R.L., Rome, Italy.
Zambrano N; Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli Federico II, Via Pansini 5, 80131, Napoli, NA, Italy. .; CEINGE Biotecnologie Avanzate Franco Salvatore S.C.aR.L., Via Gaetano Salvatore 486, 80145, Naples, Italy. .
Sasso E; Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli Federico II, Via Pansini 5, 80131, Napoli, NA, Italy. .; CEINGE Biotecnologie Avanzate Franco Salvatore S.C.aR.L., Via Gaetano Salvatore 486, 80145, Naples, Italy. .; ImGen-T Srl, Viale del Parco Carelli, Napoli, NA, Italy. .
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Źródło:
Scientific reports [Sci Rep] 2023 Nov 09; Vol. 13 (1), pp. 19541. Date of Electronic Publication: 2023 Nov 09.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Communicable Diseases*/genetics
Interferon Type I*/metabolism
Neoplasms*/genetics
Virus Diseases*/genetics
Humans ; Alleles ; DNA ; Immunity, Innate/genetics ; Monocytes/metabolism
Czasopismo naukowe
Tytuł:
Generation of porcine PK-15 cells lacking the Ifnar1 or Stat2 gene to optimize the efficiency of viral isolation.
Autorzy:
Shofa M; Department of Veterinary Science, Faculty of Agriculture, University of Miyazaki, Miyazaki, Japan.; Graduate School of Medicine and Veterinary Medicine, University of Miyazaki, Miyazaki, Japan.
Saito A; Department of Veterinary Science, Faculty of Agriculture, University of Miyazaki, Miyazaki, Japan.; Graduate School of Medicine and Veterinary Medicine, University of Miyazaki, Miyazaki, Japan.; Center for Animal Disease Control, University of Miyazaki, Miyazaki, Japan.
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Źródło:
PloS one [PLoS One] 2023 Nov 08; Vol. 18 (11), pp. e0289863. Date of Electronic Publication: 2023 Nov 08 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Interferon Type I*/metabolism
Viruses*
Animals ; Swine ; STAT2 Transcription Factor/metabolism ; Cell Line ; Interferon-alpha/metabolism
Czasopismo naukowe
Tytuł:
High frequency of type I interferon auto-antibodies in a group of middle-aged HIV-infected patients: A cross-sectional exploratory study.
Autorzy:
Imberti L; Section of Microbiology, University of Brescia, Brescia, Italy.
Magro P; Department of Infectious and Tropical Diseases, University of Brescia, Brescia, Italy.
Sottini A; Clinical Chemistry Laboratory, ASST Spedali Civili of Brescia, Brescia, Italy.
Quaresima V; Clinical Chemistry Laboratory, ASST Spedali Civili of Brescia, Brescia, Italy.
Castelli F; Department of Infectious and Tropical Diseases, University of Brescia, Brescia, Italy.
Quiros-Roldan E; Department of Infectious and Tropical Diseases, University of Brescia, Brescia, Italy.
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Źródło:
Immunity, inflammation and disease [Immun Inflamm Dis] 2023 Nov; Vol. 11 (11), pp. e1056.
Typ publikacji:
Journal Article
MeSH Terms:
HIV Infections*/complications
Interferon Type I*
COVID-19*/epidemiology
COVID-19*/complications
Middle Aged ; Humans ; Cross-Sectional Studies ; SARS-CoV-2 ; Antibodies
Czasopismo naukowe

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