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Tytuł :
Utility of interferon gamma/tumor necrosis factor alpha FluoroSpot assay in differentiation between active tuberculosis and latent tuberculosis infection: a pilot study.
Autorzy :
Zhang L; Division of Infectious Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100730, China.; Clinical Epidemiology Unit, International Epidemiology Network, Peking Union Medical College Hospital, Chinese Academy of Medical Science, Beijing, 100730, China.; Centre for Tuberculosis Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Wan S; Division of Infectious Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100730, China.
Zhou Z; Peking Union Medical College Hospital, Peking Union Medical College, Beijing, China.
Zhang Y; Division of Infectious Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100730, China.
Liu X; Division of Infectious Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100730, China. .; Clinical Epidemiology Unit, International Epidemiology Network, Peking Union Medical College Hospital, Chinese Academy of Medical Science, Beijing, 100730, China. .; Centre for Tuberculosis Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. .
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Źródło :
BMC infectious diseases [BMC Infect Dis] 2021 Jul 06; Vol. 21 (1), pp. 651. Date of Electronic Publication: 2021 Jul 06.
Typ publikacji :
Journal Article
MeSH Terms :
Interferon-gamma Release Tests*
Latent Tuberculosis/*diagnosis
Tuberculosis/*diagnosis
Tumor Necrosis Factor-alpha/*blood
Adolescent ; Adult ; Aged ; Case-Control Studies ; Diagnosis, Differential ; Humans ; Interferon-gamma/blood ; Latent Tuberculosis/immunology ; Male ; Middle Aged ; Pilot Projects ; Tuberculosis/immunology ; Young Adult
Czasopismo naukowe
Tytuł :
Tuberculosis infection screening in children with close contact: a hospital-based study.
Autorzy :
Sun L; National Clinical Research Center for Respiratory Diseases, National Key Discipline of Pediatrics, Capital Medical University, Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.
Qi X; National Clinical Research Center for Respiratory Diseases, National Key Discipline of Pediatrics, Capital Medical University, Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.; Department of Respiratory, Qilu Children's Hospital of Shandong University, Jinan, China.
Guo Y; National Clinical Research Center for Respiratory Diseases, National Key Discipline of Pediatrics, Capital Medical University, Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.
Qi H; National Clinical Research Center for Respiratory Diseases, National Key Discipline of Pediatrics, Capital Medical University, Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.
Li J; National Clinical Research Center for Respiratory Diseases, National Key Discipline of Pediatrics, Capital Medical University, Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.
Wu X; National Clinical Research Center for Respiratory Diseases, National Key Discipline of Pediatrics, Capital Medical University, Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.
Yin Q; National Clinical Research Center for Respiratory Diseases, National Key Discipline of Pediatrics, Capital Medical University, Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.
Guo Y; National Clinical Research Center for Respiratory Diseases, National Key Discipline of Pediatrics, Capital Medical University, Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.
Xu B; National Clinical Research Center for Respiratory Diseases, National Key Discipline of Pediatrics, Capital Medical University, Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.
Wang Y; National Clinical Research Center for Respiratory Diseases, National Key Discipline of Pediatrics, Capital Medical University, Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.
Jin Q; MOH Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, and Centre for Tuberculosis, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Gao L; MOH Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, and Centre for Tuberculosis, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. .
Shen A; National Clinical Research Center for Respiratory Diseases, National Key Discipline of Pediatrics, Capital Medical University, Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China. .
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Źródło :
BMC infectious diseases [BMC Infect Dis] 2021 Aug 13; Vol. 21 (1), pp. 815. Date of Electronic Publication: 2021 Aug 13.
Typ publikacji :
Journal Article
MeSH Terms :
Interferon-gamma Release Tests/*methods
Latent Tuberculosis/*diagnosis
Mass Screening/*methods
Tuberculin Test/*methods
Child ; Child, Preschool ; Contact Tracing/methods ; Female ; Hospitals ; Humans ; Interferon-gamma/metabolism ; Latent Tuberculosis/epidemiology ; Male ; Tuberculosis/diagnosis ; Tuberculosis/epidemiology
Czasopismo naukowe
Tytuł :
Broad T Cell Targeting of Structural Proteins After SARS-CoV-2 Infection: High Throughput Assessment of T Cell Reactivity Using an Automated Interferon Gamma Release Assay.
Autorzy :
Brand I; Division of Infectious Diseases and Tropical Medicine, University Hospital, Ludwig-Maximilians-Universität (LMU) Munich, Munich, Germany.; Division of Clinical Pharmacology, Department of Medicine IV, University Hospital, LMU Munich, Munich, Germany.
Gilberg L; Division of Infectious Diseases and Tropical Medicine, University Hospital, Ludwig-Maximilians-Universität (LMU) Munich, Munich, Germany.; Department of Infectious Diseases, University Hospital, LMU Munich, Munich, Germany.
Bruger J; Division of Infectious Diseases and Tropical Medicine, University Hospital, Ludwig-Maximilians-Universität (LMU) Munich, Munich, Germany.
Garí M; Institute of Computational Biology, Helmholtz Zentrum München - German Research Center for Environmental Health (HMGU), Neuherberg, Germany.
Wieser A; Division of Infectious Diseases and Tropical Medicine, University Hospital, Ludwig-Maximilians-Universität (LMU) Munich, Munich, Germany.; German Center for Infection Research (DZIF), Partner Site Munich, Munich, Germany.
Eser TM; Division of Infectious Diseases and Tropical Medicine, University Hospital, Ludwig-Maximilians-Universität (LMU) Munich, Munich, Germany.; German Center for Infection Research (DZIF), Partner Site Munich, Munich, Germany.
Frese J; Division of Infectious Diseases and Tropical Medicine, University Hospital, Ludwig-Maximilians-Universität (LMU) Munich, Munich, Germany.
Ahmed MIM; Division of Infectious Diseases and Tropical Medicine, University Hospital, Ludwig-Maximilians-Universität (LMU) Munich, Munich, Germany.; German Center for Infection Research (DZIF), Partner Site Munich, Munich, Germany.
Rubio-Acero R; Division of Infectious Diseases and Tropical Medicine, University Hospital, Ludwig-Maximilians-Universität (LMU) Munich, Munich, Germany.
Guggenbuehl Noller JM; Division of Infectious Diseases and Tropical Medicine, University Hospital, Ludwig-Maximilians-Universität (LMU) Munich, Munich, Germany.
Castelletti N; Division of Infectious Diseases and Tropical Medicine, University Hospital, Ludwig-Maximilians-Universität (LMU) Munich, Munich, Germany.
Diekmannshemke J; Institute of Computational Biology, Helmholtz Zentrum München - German Research Center for Environmental Health (HMGU), Neuherberg, Germany.; Faculty of Business Administration and Economics, Bielefeld University, Bielefeld, Germany.
Thiesbrummel S; Institute of Computational Biology, Helmholtz Zentrum München - German Research Center for Environmental Health (HMGU), Neuherberg, Germany.; Faculty of Business Administration and Economics, Bielefeld University, Bielefeld, Germany.
Huynh D; Division of Clinical Pharmacology, Department of Medicine IV, University Hospital, LMU Munich, Munich, Germany.
Winter S; Division of Infectious Diseases and Tropical Medicine, University Hospital, Ludwig-Maximilians-Universität (LMU) Munich, Munich, Germany.
Kroidl I; Division of Infectious Diseases and Tropical Medicine, University Hospital, Ludwig-Maximilians-Universität (LMU) Munich, Munich, Germany.; German Center for Infection Research (DZIF), Partner Site Munich, Munich, Germany.
Fuchs C; Institute of Computational Biology, Helmholtz Zentrum München - German Research Center for Environmental Health (HMGU), Neuherberg, Germany.; Faculty of Business Administration and Economics, Bielefeld University, Bielefeld, Germany.; Center for Mathematics, Technische Universität München, Garching, Germany.
Hoelscher M; Division of Infectious Diseases and Tropical Medicine, University Hospital, Ludwig-Maximilians-Universität (LMU) Munich, Munich, Germany.; German Center for Infection Research (DZIF), Partner Site Munich, Munich, Germany.; Center for International Health (CIH), University Hospital, LMU Munich, Munich, Germany.
Roider J; Department of Infectious Diseases, University Hospital, LMU Munich, Munich, Germany.; German Center for Infection Research (DZIF), Partner Site Munich, Munich, Germany.
Kobold S; Division of Clinical Pharmacology, Department of Medicine IV, University Hospital, LMU Munich, Munich, Germany.; German Center for Translational Cancer Research (DKTK), Partner Site Munich, Munich, Germany.; Unit for Clinical Pharmacology (EKLiP), Helmholtz Zentrum München - German Research Center for Environmental Health (HMGU), Neuherberg, Germany.
Pritsch M; Division of Infectious Diseases and Tropical Medicine, University Hospital, Ludwig-Maximilians-Universität (LMU) Munich, Munich, Germany.; German Center for Infection Research (DZIF), Partner Site Munich, Munich, Germany.
Geldmacher C; Division of Infectious Diseases and Tropical Medicine, University Hospital, Ludwig-Maximilians-Universität (LMU) Munich, Munich, Germany.; German Center for Infection Research (DZIF), Partner Site Munich, Munich, Germany.
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Źródło :
Frontiers in immunology [Front Immunol] 2021 May 20; Vol. 12, pp. 688436. Date of Electronic Publication: 2021 May 20 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
COVID-19/*immunology
Interferon-gamma/*immunology
SARS-CoV-2/*immunology
T-Lymphocytes/*immunology
Viral Structural Proteins/*immunology
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Antibodies, Viral/blood ; COVID-19/blood ; Female ; Humans ; Interferon-gamma Release Tests ; Male ; Middle Aged ; Young Adult
Czasopismo naukowe
Tytuł :
Reporting of interferon-gamma release assay results close to cut-off values.
Autorzy :
Folkvardsen DB; International Reference Laboratory of Mycobacteriology, Statens Serum Institut, Copenhagen, Denmark.
Holicka Y; National Mycobacterium Reference Service South, Public Health England, London, UK.
Ködmön C; European Center for Disease Prevention and Control, Stockholm, Sweden.
van der Werf MJ; European Center for Disease Prevention and Control, Stockholm, Sweden.
Lillebaek T; International Reference Laboratory of Mycobacteriology, Statens Serum Institut, Copenhagen, Denmark, Global Health Section, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Nikolayevskyy V; National Mycobacterium Reference Service South, Public Health England, London, UK, Imperial College London, London, UK.
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Źródło :
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease [Int J Tuberc Lung Dis] 2021 Jan 01; Vol. 25 (1), pp. 66-68.
Typ publikacji :
Letter; Research Support, Non-U.S. Gov't
MeSH Terms :
Interferon-gamma Release Tests*
Tuberculin Test*
Humans ; Interferon-gamma
Raport
Tytuł :
The co-stimulation of anti-CD28 and IL-2 enhances the sensitivity of ELISPOT assays for detection of neoantigen-specific T cells in PBMC.
Autorzy :
Tang Y; BGI Education Center, University of Chinese Academy of Sciences, Shenzhen 518083, China; BGI-Shenzhen, Shenzhen 518083, China.
Zhu L; BGI-Shenzhen, Shenzhen 518083, China.
Xu Q; BGI-Shenzhen, Shenzhen 518083, China.
Zhang X; BGI Education Center, University of Chinese Academy of Sciences, Shenzhen 518083, China; BGI-Shenzhen, Shenzhen 518083, China; BGI-GenoImmune, Wuhan 490079, China. Electronic address: .
Li B; BGI-Shenzhen, Shenzhen 518083, China; BGI-GenoImmune, Wuhan 490079, China. Electronic address: .
Lee LJ; BGI-Shenzhen, Shenzhen 518083, China; BGI-GenoImmune, Wuhan 490079, China; Department of Electrical and Computer Engineering, Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario M5S 3G4, Canada. Electronic address: .
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Źródło :
Journal of immunological methods [J Immunol Methods] 2020 Sep - Oct; Vol. 484-485, pp. 112831. Date of Electronic Publication: 2020 Aug 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Enzyme-Linked Immunospot Assay*
Interferon-gamma Release Tests*
Antibodies/*pharmacology
Antigens, Neoplasm/*immunology
CD28 Antigens/*immunology
Interleukin-2/*pharmacology
Lymphocyte Activation/*drug effects
Neoplasms/*immunology
T-Lymphocytes/*drug effects
Antigens, Neoplasm/genetics ; Antigens, Neoplasm/metabolism ; Cells, Cultured ; Drug Synergism ; Humans ; Interferon-gamma/immunology ; Interferon-gamma/metabolism ; MART-1 Antigen/immunology ; Mutation ; Neoplasms/genetics ; Neoplasms/metabolism ; Peptide Fragments/immunology ; Reproducibility of Results ; Signal Transduction ; T-Lymphocytes/immunology ; T-Lymphocytes/metabolism ; Viral Matrix Proteins/immunology
Czasopismo naukowe
Tytuł :
Alternative biomarkers for classification of latent tuberculosis infection status in pregnant women with borderline Quantiferon plus results.
Autorzy :
Tesfaye F; Clinical Infection Medicine, Department of Translational Medicine, Lund University, Malmö, Sweden; Armauer Hansen Research Institute, Addis Ababa, Ethiopia. Electronic address: .
Sturegård E; Clinical Infection Medicine, Department of Translational Medicine, Lund University, Malmö, Sweden; Clinical Microbiology, Division of Laboratory Medicine, Lund, Sweden.
Walles J; Clinical Infection Medicine, Department of Translational Medicine, Lund University, Malmö, Sweden; Department of Infectious Diseases, Central Hospital, Kristianstad, Sweden.
Winqvist N; Clinical Infection Medicine, Department of Translational Medicine, Lund University, Malmö, Sweden.
Balcha TT; Clinical Infection Medicine, Department of Translational Medicine, Lund University, Malmö, Sweden.
Karlson S; Medical Microbiology, Department of Laboratory Medicine, Lund University, Lund, Sweden.
Mulleta D; Adama Public Health Research and Referral Laboratory Center, Adama, Ethiopia.
Isberg PE; Department of Statistics, School of Economics and Management, Lund University, Lund, Sweden.
Jansson M; Medical Microbiology, Department of Laboratory Medicine, Lund University, Lund, Sweden.
Björkman P; Clinical Infection Medicine, Department of Translational Medicine, Lund University, Malmö, Sweden; Department of Infectious Diseases, Skane University Hospital, Malmö, Sweden.
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Źródło :
Tuberculosis (Edinburgh, Scotland) [Tuberculosis (Edinb)] 2020 Sep; Vol. 124, pp. 101984. Date of Electronic Publication: 2020 Aug 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Interferon-gamma Release Tests*
Cytokines/*blood
Latent Tuberculosis/*diagnosis
Mycobacterium tuberculosis/*immunology
Pregnancy Complications, Infectious/*diagnosis
Adult ; Biomarkers/blood ; Chemokine CCL8/blood ; Chemokine CXCL10/blood ; Ethiopia ; Female ; Host-Pathogen Interactions ; Humans ; Interferon-gamma/blood ; Interleukin 1 Receptor Antagonist Protein/blood ; Latent Tuberculosis/blood ; Latent Tuberculosis/immunology ; Latent Tuberculosis/microbiology ; Mycobacterium tuberculosis/pathogenicity ; Predictive Value of Tests ; Pregnancy ; Pregnancy Complications, Infectious/blood ; Pregnancy Complications, Infectious/immunology ; Pregnancy Complications, Infectious/microbiology ; Prospective Studies ; Reproducibility of Results ; Young Adult
Czasopismo naukowe
Tytuł :
Type I, II, and III Interferon Signatures Correspond to Coronavirus Disease 2019 Severity.
Autorzy :
Kim MH; Liver Center, GI Division, Massachusetts General Hospital, Boston, Massachusetts, USA.
Salloum S; Liver Center, GI Division, Massachusetts General Hospital, Boston, Massachusetts, USA.
Wang JY; Liver Center, GI Division, Massachusetts General Hospital, Boston, Massachusetts, USA.
Wong LP; Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts,USA.
Regan J; Department of Infectious Diseases, Brigham and Women's Hospital, Boston, Massachusetts,USA.
Lefteri K; Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts,USA.
Manickas-Hill Z; Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts,USA.
Gao C; Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts,USA.
Li JZ; Department of Infectious Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts,USA.
Sadreyev RI; Department of Molecular Biology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts,USA.
Yu XG; Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts,USA.; Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts,USA.
Chung RT; Liver Center, GI Division, Massachusetts General Hospital, Boston, Massachusetts, USA.
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Corporate Authors :
MGH COVID-19 Collection & Processing Team
Źródło :
The Journal of infectious diseases [J Infect Dis] 2021 Sep 01; Vol. 224 (5), pp. 777-782.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
COVID-19/*immunology
Interferon Type I/*immunology
Interferon-gamma/*immunology
Interferons/*immunology
COVID-19/blood ; Chemokines/blood ; Cytokines/blood ; Humans ; Interferon Type I/blood ; Interferon Type I/genetics ; Interferon-gamma/blood ; Interferon-gamma/genetics ; Interferons/blood ; Leukocytes, Mononuclear/immunology ; SARS-CoV-2/isolation & purification
Czasopismo naukowe
Tytuł :
Enhancement of interferon gamma stability as an anticancer therapeutic protein against hepatocellular carcinoma upon interaction with calycosin.
Autorzy :
Yang H; Department of Gastroenterology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, PR China. Electronic address: .
Khan S; Department of Cerebrovascular Diseases, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, PR China.
Sun A; Henan Institute of Medical and Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, PR China.
Bai Q; Department of Anesthesiology, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, PR China. Electronic address: .
Cheng H; Henan Institute of Medical and Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, PR China.
Akhtari K; Department of Physics, University of Kurdistan, Sanandaj, Iran.
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Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2021 Aug 31; Vol. 185, pp. 813-820. Date of Electronic Publication: 2021 Jun 27.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*pharmacology
Carcinoma, Hepatocellular/*metabolism
Caspase 3/*metabolism
Caspase 9/*metabolism
Interferon-gamma/*pharmacology
Isoflavones/*chemistry
Liver Neoplasms/*metabolism
Antineoplastic Agents/chemistry ; Carcinoma, Hepatocellular/drug therapy ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Drug Stability ; Gene Expression Regulation, Neoplastic/drug effects ; Hep G2 Cells ; Humans ; Interferon-gamma/chemistry ; Liver Neoplasms/drug therapy ; Protein Folding/drug effects ; Thermodynamics
Czasopismo naukowe
Tytuł :
Effect of refrigeration of blood samples in lithium-heparin tubes on QuantiFERON TB Gold Plus test result.
Autorzy :
Uwamino Y; Department of Laboratory Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, Japan; Department of Infectious Diseases, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, Japan.
Sakai A; Department of Laboratory Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, Japan.
Nishimura T; Health Center, Keio University, 35 Shinanomachi, Shinjuku-ku, Tokyo, Japan.
Noguchi M; Department of Laboratory Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, Japan.
Uno S; Department of Infectious Diseases, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, Japan.
Fujiwara H; Department of Infectious Diseases, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, Japan.
Mori M; Health Center, Keio University, 35 Shinanomachi, Shinjuku-ku, Tokyo, Japan.
Wakui M; Department of Laboratory Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, Japan.
Murata M; Department of Laboratory Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, Japan.
Hasegawa N; Department of Infectious Diseases, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, Japan. Electronic address: .
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Źródło :
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy [J Infect Chemother] 2020 Mar; Vol. 26 (3), pp. 312-314. Date of Electronic Publication: 2019 Dec 10.
Typ publikacji :
Journal Article
MeSH Terms :
Interferon-gamma Release Tests*/methods
Interferon-gamma Release Tests*/standards
Blood Specimen Collection/*methods
Latent Tuberculosis/*diagnosis
Adult ; Aged ; Cold Temperature ; Female ; Heparin ; Humans ; Interferon-gamma/analysis ; Interferon-gamma/metabolism ; Lithium ; Male ; Middle Aged ; Reproducibility of Results
Czasopismo naukowe
Tytuł :
An interferon-gamma release assay as a novel biomarker in systemic lupus erythematosus.
Autorzy :
Thomason JL; Department of Medicine, Division of Rheumatology, University of Washington.
Obih UM; Department of Medicine, Division of Rheumatology, University of Washington.; Department of Rheumatology, Swedish Medical Center.
Koelle DM; Department of Medicine, Division of Infectious Diseases, University of Washington.; Department of Laboratory Medicine, University of Washington.; Department of Global Health, University of Washington.; Fred Hutchinson Cancer Research Center.; Benaroya Research Institute, Seattle, WA, USA.
Lood C; Department of Medicine, Division of Rheumatology, University of Washington.
Hughes AG; Department of Medicine, Division of Rheumatology, University of Washington.
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Źródło :
Rheumatology (Oxford, England) [Rheumatology (Oxford)] 2020 Nov 01; Vol. 59 (11), pp. 3479-3487.
Typ publikacji :
Journal Article
MeSH Terms :
Interferon-gamma Release Tests*
Autoantibodies/*immunology
Interferon-gamma/*immunology
Lupus Erythematosus, Systemic/*immunology
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Arthritis/physiopathology ; Complement System Proteins/immunology ; Female ; Fever/physiopathology ; HIV Infections/immunology ; Humans ; Leukopenia/physiopathology ; Lupus Erythematosus, Cutaneous/immunology ; Lupus Erythematosus, Cutaneous/physiopathology ; Lupus Erythematosus, Systemic/physiopathology ; Lymphohistiocytosis, Hemophagocytic/immunology ; Male ; Middle Aged ; Serositis/physiopathology ; Thrombocytopenia/physiopathology ; Tuberculosis/immunology ; Young Adult
Czasopismo naukowe
Tytuł :
Neutralizing Anti-interferon-γ Autoantibodies: an Ameliorating Factor in COVID-19 Infection?
Autorzy :
Kacar M; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Wellcome Trust Brenner Building, St. James University, Beckett Street, Leeds, LS9 7TF, UK.; Department of Clinical Immunology and Allergy, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Cortes-Acevedo P; Laboratorio 2 Inmunologia, FES-Cuautitlán, UNAM, Cuautitlán Izcalli, Mexico.
Patel V; Department of Infectious Diseases, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Carter C; Department of Transplant and Cellular Immunology, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Hughes P; Department of Transplant and Cellular Immunology, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
McGann HP; Department of Infectious Diseases, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Gkrania-Klotsas E; Department of Infectious Diseases, Cambridge University NHS Hospitals Foundation Trust, Cambridge, UK.
Baxendale HE; Royal Papworth Hospital NHS Foundation Trust, Cambridge, UK.
Barcenas-Morales G; Laboratorio 2 Inmunologia, FES-Cuautitlán, UNAM, Cuautitlán Izcalli, Mexico.
Doffinger R; Department of Clinical Biochemistry and Immunology, Addenbrooke's Hospital, Cambridge, CB2 2QQ, UK.
Savic S; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Wellcome Trust Brenner Building, St. James University, Beckett Street, Leeds, LS9 7TF, UK. .; Department of Clinical Immunology and Allergy, Leeds Teaching Hospitals NHS Trust, Leeds, UK. .
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Źródło :
Journal of clinical immunology [J Clin Immunol] 2021 Oct; Vol. 41 (7), pp. 1531-1535. Date of Electronic Publication: 2021 Jul 26.
Typ publikacji :
Case Reports; Letter; Research Support, Non-U.S. Gov't
MeSH Terms :
Antibodies, Neutralizing/*metabolism
Autoantibodies/*metabolism
COVID-19/*diagnosis
Interferon-gamma/*genetics
Mycobacterium Infections, Nontuberculous/*diagnosis
Nontuberculous Mycobacteria/*physiology
SARS-CoV-2/*physiology
Coinfection ; Humans ; Interferon-gamma/immunology ; Male ; Middle Aged ; Severity of Illness Index
Raport
Tytuł :
Between immunomodulation and immunotolerance: The role of IFNγ in SARS-CoV-2 disease.
Autorzy :
Todorović-Raković N; Department of Experimental Oncology, Institute for Oncology and Radiology of Serbia, Belgrade, Serbia. Electronic address: .
Whitfield JR; Vall d'Hebron Institute of Oncology (VHIO), Carrer Natzaret 115, Vall d'Hebron Barcelona Hospital Campus, 08035 Barcelona, Spain.
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Źródło :
Cytokine [Cytokine] 2021 Oct; Vol. 146, pp. 155637. Date of Electronic Publication: 2021 Jul 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Adaptive Immunity/*immunology
COVID-19/*immunology
Immune Tolerance/*immunology
Immunity, Innate/*immunology
Interferon-gamma/*immunology
Antiviral Agents/immunology ; Antiviral Agents/therapeutic use ; COVID-19/drug therapy ; COVID-19/virology ; Humans ; Interferon-gamma/therapeutic use ; Receptors, Interferon/immunology ; SARS-CoV-2/drug effects ; SARS-CoV-2/immunology ; SARS-CoV-2/physiology ; Signal Transduction/immunology
Czasopismo naukowe
Tytuł :
Characterisation and analysis of IFN-gamma producing cells in rainbow trout Oncorhynchus mykiss.
Autorzy :
Hu Y; Scottish Fish Immunology Research Centre, University of Aberdeen, Aberdeen, UK.
Alnabulsi A; Vertebrate Antibodies Ltd, Aberdeen, UK.
Alnabulsi A; AiBIOLOGICS, Dublin, Ireland.
Scott C; Scottish Fish Immunology Research Centre, University of Aberdeen, Aberdeen, UK.
Tafalla C; INIA, Madrid, Spain.
Secombes CJ; Scottish Fish Immunology Research Centre, University of Aberdeen, Aberdeen, UK.
Wang T; Scottish Fish Immunology Research Centre, University of Aberdeen, Aberdeen, UK. Electronic address: .
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Źródło :
Fish & shellfish immunology [Fish Shellfish Immunol] 2021 Oct; Vol. 117, pp. 328-338. Date of Electronic Publication: 2021 Jul 31.
Typ publikacji :
Journal Article
MeSH Terms :
Fish Proteins/*immunology
Interferon-gamma/*immunology
Oncorhynchus mykiss/*immunology
Aeromonas salmonicida ; Animals ; Antibodies, Monoclonal/immunology ; Fish Diseases/immunology ; Fish Proteins/genetics ; Gram-Negative Bacterial Infections/immunology ; Gram-Negative Bacterial Infections/veterinary ; HEK293 Cells ; Head Kidney/immunology ; Humans ; Interferon-gamma/genetics ; Leukocytes/immunology ; Oncorhynchus mykiss/genetics ; Oncorhynchus mykiss/microbiology ; Spleen/immunology
Czasopismo naukowe
Tytuł :
The Initial QuantiFERON-Lyme Prototype is Unsuitable for European Patients.
Autorzy :
Baarsma ME; Amsterdam UMC, University of Amsterdam, Center for Experimental and Molecular Medicine, Amsterdam Institute for Infection and Immunology, Amsterdam, The Netherlands.
van de Schoor FR; Radboudumc, Department of Internal Medicine, Radboud Center for Infectious Diseases (RCI) and Radboud Institute of Health Sciences (RIHS), Nijmegen, The Netherlands.
Van den Wijngaard CC; National Institute for Public Health and the Environment (RIVM), Center of Infectious Disease Control, Bilthoven, The Netherlands.
Joosten LAB; Radboudumc, Department of Internal Medicine, Radboud Center for Infectious Diseases (RCI) and Radboud Institute of Health Sciences (RIHS), Nijmegen, The Netherlands.
Kullberg BJ; Radboudumc, Department of Internal Medicine, Radboud Center for Infectious Diseases (RCI) and Radboud Institute of Health Sciences (RIHS), Nijmegen, The Netherlands.
Hovius JW; Amsterdam UMC, University of Amsterdam, Center for Experimental and Molecular Medicine, Amsterdam Institute for Infection and Immunology, Amsterdam, The Netherlands.
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Źródło :
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2021 Sep 15; Vol. 73 (6), pp. 1125-1126.
Typ publikacji :
Letter; Research Support, Non-U.S. Gov't; Comment
MeSH Terms :
Interferon-gamma Release Tests*
Lyme Disease*
Antibodies, Bacterial ; Humans
Raport
Tytuł :
Fewer losses in the cascade of care for latent tuberculosis with solo interferon-gamma release assay screening compared to sequential screening.
Autorzy :
Lim RK; Cumming School of Medicine, University of Calgary, Alberta, Canada. .
Talavlikar R; Mosaic Refugee Health Clinic, Mosaic Primary Care Network, Calgary, AB, Canada.
Chiazor O; Mosaic Refugee Health Clinic, Mosaic Primary Care Network, Calgary, AB, Canada.
Bietz J; Mosaic Refugee Health Clinic, Mosaic Primary Care Network, Calgary, AB, Canada.
Gardiner H; Calgary Tuberculosis Services, Alberta Health Services, Calgary, AB, Canada.
Fisher D; Cumming School of Medicine, University of Calgary, Alberta, Canada.
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Źródło :
BMC infectious diseases [BMC Infect Dis] 2021 Sep 09; Vol. 21 (1), pp. 936. Date of Electronic Publication: 2021 Sep 09.
Typ publikacji :
Journal Article
MeSH Terms :
Interferon-gamma Release Tests*
Latent Tuberculosis*/diagnosis
Latent Tuberculosis*/epidemiology
Humans ; Mass Screening ; Retrospective Studies ; Tuberculin Test
Czasopismo naukowe
Tytuł :
Suppression of CD80 Expression by ICP22 Affects Herpes Simplex Virus Type 1 Replication and CD8 Infiltrates in the Eyes of Infected Mice but Not Latency Reactivation.
Autorzy :
Matundan HH; Center for Neurobiology and Vaccine Development, Ophthalmology Research, Department of Surgery, Cedars-Sinai Burns and Allen Research Institute, CSMC-SSB3, Los Angeles, California, USA.
Wang S; Center for Neurobiology and Vaccine Development, Ophthalmology Research, Department of Surgery, Cedars-Sinai Burns and Allen Research Institute, CSMC-SSB3, Los Angeles, California, USA.
Jaggi U; Center for Neurobiology and Vaccine Development, Ophthalmology Research, Department of Surgery, Cedars-Sinai Burns and Allen Research Institute, CSMC-SSB3, Los Angeles, California, USA.
Yu J; Center for Neurobiology and Vaccine Development, Ophthalmology Research, Department of Surgery, Cedars-Sinai Burns and Allen Research Institute, CSMC-SSB3, Los Angeles, California, USA.
Ghiasi H; Center for Neurobiology and Vaccine Development, Ophthalmology Research, Department of Surgery, Cedars-Sinai Burns and Allen Research Institute, CSMC-SSB3, Los Angeles, California, USA.
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Źródło :
Journal of virology [J Virol] 2021 Sep 09; Vol. 95 (19), pp. e0103621. Date of Electronic Publication: 2021 Sep 09.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Virus Latency*
B7-1 Antigen/*genetics
Herpesvirus 1, Human/*physiology
Immediate-Early Proteins/*metabolism
Interferon-gamma/*metabolism
Keratitis, Herpetic/*virology
Animals ; B7-1 Antigen/metabolism ; CD4-Positive T-Lymphocytes/immunology ; CD4-Positive T-Lymphocytes/metabolism ; CD8-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/metabolism ; Cell Line ; Cornea/immunology ; Cornea/virology ; Dendritic Cells/immunology ; Dendritic Cells/metabolism ; Herpesvirus 1, Human/genetics ; Herpesvirus 1, Human/immunology ; Humans ; Immediate-Early Proteins/chemistry ; Immediate-Early Proteins/genetics ; Immune Evasion ; Interferon-gamma/genetics ; Mice ; Mice, Inbred BALB C ; Promoter Regions, Genetic ; Recombinant Proteins/chemistry ; Recombinant Proteins/metabolism ; Tears/virology ; Up-Regulation ; Virus Activation ; Virus Replication
Czasopismo naukowe
Tytuł :
Infection-induced type I interferons critically modulate the homeostasis and function of CD8 naïve T cells.
Autorzy :
Jergović M; Department of Immunobiology and the University of Arizona Center on Aging, University of Arizona College of Medicine, Tucson, AZ, USA.
Coplen CP; Department of Immunobiology and the University of Arizona Center on Aging, University of Arizona College of Medicine, Tucson, AZ, USA.
Uhrlaub JL; Department of Immunobiology and the University of Arizona Center on Aging, University of Arizona College of Medicine, Tucson, AZ, USA.
Besselsen DG; University Animal Care, University of Arizona, Tucson, AZ, USA.
Cheng S; Department of Medicine, University of Arizona College of Medicine, Tucson, AZ, USA.
Smithey MJ; Department of Immunobiology and the University of Arizona Center on Aging, University of Arizona College of Medicine, Tucson, AZ, USA.; Vir, Inc., San Francisco, CA, USA.
Nikolich-Žugich J; Department of Immunobiology and the University of Arizona Center on Aging, University of Arizona College of Medicine, Tucson, AZ, USA. .
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Źródło :
Nature communications [Nat Commun] 2021 Sep 06; Vol. 12 (1), pp. 5303. Date of Electronic Publication: 2021 Sep 06.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Antigens, Ly/*genetics
CD8-Positive T-Lymphocytes/*immunology
Homeostasis/*genetics
Immunologic Memory/*genetics
Interferon-alpha/*genetics
Interferon-gamma/*genetics
West Nile Fever/*genetics
Animals ; Antigens, Ly/immunology ; CD4-Positive T-Lymphocytes/immunology ; CD4-Positive T-Lymphocytes/virology ; CD5 Antigens/genetics ; CD5 Antigens/immunology ; CD8 Antigens/genetics ; CD8 Antigens/immunology ; CD8-Positive T-Lymphocytes/virology ; Cell Differentiation ; Female ; Gene Expression Profiling ; Gene Expression Regulation ; Homeostasis/immunology ; Interferon-alpha/immunology ; Interferon-gamma/immunology ; Interleukin-7/genetics ; Interleukin-7/immunology ; Lymphocyte Activation ; Mice ; Mice, Inbred C57BL ; Receptors, Antigen, T-Cell/genetics ; Receptors, Antigen, T-Cell/immunology ; Signal Transduction ; West Nile Fever/immunology ; West Nile Fever/pathology ; West Nile Fever/virology ; West Nile virus/immunology ; West Nile virus/pathogenicity
Czasopismo naukowe
Tytuł :
IFN- γ Licensing Does Not Enhance the Reduced Immunomodulatory Potential and Migratory Ability of Differentiation-Induced Porcine Bone Marrow-Derived Mesenchymal Stem Cells in an In Vitro Xenogeneic Application.
Autorzy :
Lee HJ; College of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Republic of Korea.
Kim HD; College of Veterinary Medicine, Kyungpook National University, Daegu 41566, Republic of Korea.; Department of Veterinary Research, Daegu Metropolitan City Institute of Health & Environment, Daegu 42183, Republic of Korea.
Jo CH; College of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Republic of Korea.
Bok EY; College of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Republic of Korea.
Kim SB; College of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Republic of Korea.
Lee SL; College of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Republic of Korea.
Jang M; College of Veterinary Medicine, Kyungpook National University, Daegu 41566, Republic of Korea.
Bae SG; College of Veterinary Medicine, Kyungpook National University, Daegu 41566, Republic of Korea.
Yun SH; College of Veterinary Medicine, Kyungpook National University, Daegu 41566, Republic of Korea.
Kim SJ; College of Veterinary Medicine, Kyungpook National University, Daegu 41566, Republic of Korea.
Rho GJ; College of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Republic of Korea.
Lee WJ; College of Veterinary Medicine, Kyungpook National University, Daegu 41566, Republic of Korea.
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Źródło :
BioMed research international [Biomed Res Int] 2021 Sep 04; Vol. 2021, pp. 4604856. Date of Electronic Publication: 2021 Sep 04 (Print Publication: 2021).
Typ publikacji :
Journal Article
MeSH Terms :
Interferon-gamma/*metabolism
Mesenchymal Stem Cell Transplantation/*methods
Mesenchymal Stem Cells/*metabolism
Animals ; Bone Marrow/metabolism ; Bone Marrow Cells/metabolism ; Cell Differentiation/drug effects ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Cells, Cultured ; Coculture Techniques ; Cytokines/metabolism ; Heterografts/metabolism ; Humans ; Immunomodulation/drug effects ; Interferon-gamma/physiology ; Mesenchymal Stem Cells/physiology ; Osteogenesis/drug effects ; Swine ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł :
An Interferon-γ Release Assay for Evaluation of Cell-mediated Immunity in Infants With Congenital Cytomegalovirus Infection.
Autorzy :
Gibson L; University of Massachusetts Medical School, Departments of Medicine and Pediatrics, Division of Infectious Diseases and Immunology, Worcester, Massachusetts, USA.
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Źródło :
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2021 Aug 02; Vol. 73 (3), pp. 374-375.
Typ publikacji :
Editorial; Comment
MeSH Terms :
Cytomegalovirus Infections*/diagnosis
Interferon-gamma Release Tests*
DNA ; Humans ; Immunity, Cellular ; Infant ; Monitoring, Immunologic
Opinia redakcyjna
Tytuł :
Interferon γ neutralization reduces blood pressure, uterine artery resistance index, and placental oxidative stress in placental ischemic rats.
Autorzy :
Travis OK; Department of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, Mississippi.
Tardo GA; Department of Emergency Medicine, University of Mississippi Medical Center, Jackson, Mississippi.
Giachelli C; Department of Emergency Medicine, University of Mississippi Medical Center, Jackson, Mississippi.
Siddiq S; Department of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, Mississippi.
Nguyen HT; Department of Emergency Medicine, University of Mississippi Medical Center, Jackson, Mississippi.
Crosby MT; Department of Emergency Medicine, University of Mississippi Medical Center, Jackson, Mississippi.
Johnson TD; Department of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, Mississippi.
Brown AK; Department of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, Mississippi.
Booz GW; Department of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, Mississippi.
Smith AN; Department of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, Mississippi.
Williams JM; Department of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, Mississippi.
Cornelius DC; Department of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, Mississippi.; Department of Emergency Medicine, University of Mississippi Medical Center, Jackson, Mississippi.
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Źródło :
American journal of physiology. Regulatory, integrative and comparative physiology [Am J Physiol Regul Integr Comp Physiol] 2021 Aug 01; Vol. 321 (2), pp. R112-R124. Date of Electronic Publication: 2021 Jun 02.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Antibodies, Monoclonal/*pharmacology
Arterial Pressure/*drug effects
Interferon-gamma/*antagonists & inhibitors
Killer Cells, Natural/*drug effects
Oxidative Stress/*drug effects
Placenta/*blood supply
Placenta/*drug effects
Pre-Eclampsia/*prevention & control
Uterine Artery/*drug effects
Vascular Resistance/*drug effects
Angiogenic Proteins/metabolism ; Animals ; Disease Models, Animal ; Female ; Fetal Growth Retardation/metabolism ; Fetal Growth Retardation/physiopathology ; Fetal Growth Retardation/prevention & control ; Interferon-gamma/metabolism ; Ischemia/metabolism ; Ischemia/physiopathology ; Killer Cells, Natural/metabolism ; Placenta/metabolism ; Placental Circulation ; Pre-Eclampsia/metabolism ; Pre-Eclampsia/physiopathology ; Pregnancy ; Rats, Sprague-Dawley ; Reactive Oxygen Species/metabolism ; Uterine Artery/metabolism ; Uterine Artery/physiopathology
Czasopismo naukowe

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