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Tytuł:
Cytokine and T cell responses in post-chikungunya viral arthritis: A cross-sectional study.
Autorzy:
Chang AY; Department of Medicine, George Washington University, Washington, DC, United States of America.
Tritsch SR; Department of Global Health, Milken Institute School of Public Health, George Washington University, Washington, DC, United States of America.
Herrera Gomez CA; Department of Medicine, George Washington University, Washington, DC, United States of America.
Encinales L; Department of Medicine, Allied Research Society, Barranquilla, Atlántico, Colombia.
Cadena Bonfanti A; Centro de Investigación, Clínica de la Costa SAS, Barranquilla, Atlántico, Colombia.
Rosales W; Advanced Biomedicine Research Group, Universidad Libre de Colombia, Seccional Barranquilla, Barranquilla, Atlántico, Colombia.
Mendoza-Torres E; Advanced Biomedicine Research Group, Universidad Libre de Colombia, Seccional Barranquilla, Barranquilla, Atlántico, Colombia.
Simmens S; Department of Biostatistics and Bioinformatics, Milken Institute School of Public Health, George Washington University, Washington, DC, United States of America.
Amdur RL; Feinstein Institute for Medical Research, Northwell Health, Manhasset, New York, United States of America.
Mores CN; Department of Global Health, Milken Institute School of Public Health, George Washington University, Washington, DC, United States of America.
Fierbaugh P; Department of Medicine, George Washington University, Washington, DC, United States of America.
Perez Hernandez CA; Centro de Investigación, Clínica de la Costa SAS, Barranquilla, Atlántico, Colombia.
Avendaño G; Centro de Investigación, Clínica de la Costa SAS, Barranquilla, Atlántico, Colombia.
Silvera PB; Centro de Investigación, Clínica de la Costa SAS, Barranquilla, Atlántico, Colombia.
Crespo YG; Centro de Investigación, Clínica de la Costa SAS, Barranquilla, Atlántico, Colombia.
Jimenez ADC; Centro de Investigación, Clínica de la Costa SAS, Barranquilla, Atlántico, Colombia.
Martinez Zapata JC; Centro de Investigación, Clínica de la Costa SAS, Barranquilla, Atlántico, Colombia.
Jimenez D; Centro de Investigación, Clínica de la Costa SAS, Barranquilla, Atlántico, Colombia.
Osorio-Llanes E; Advanced Biomedicine Research Group, Universidad Libre de Colombia, Seccional Barranquilla, Barranquilla, Atlántico, Colombia.
Castellar-Lopez J; Advanced Biomedicine Research Group, Universidad Libre de Colombia, Seccional Barranquilla, Barranquilla, Atlántico, Colombia.
Suchowiecki K; Department of Medicine, George Washington University, Washington, DC, United States of America.
Martins K; U.S. Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America.
Gregory M; Henry M. Jackson Foundation, In Support of Austere Environments Consortium for Enhanced Sepsis Outcomes (ACESO), Bethesda, Maryland, United States of America.
Zuluaga I; Universidad Libre de Barranquilla, Clínica Iberoamérica, Barranquilla, Atlántico, Colombia.
Proctor A; Department of Global Health, Milken Institute School of Public Health, George Washington University, Washington, DC, United States of America.
Hernández AS; Department of Medicine, George Washington University, Washington, DC, United States of America.
Sierra-Carrero L; Centro de Investigación, Clínica de la Costa SAS, Barranquilla, Atlántico, Colombia.
Colpas MV; Centro de Investigación, Clínica de la Costa SAS, Barranquilla, Atlántico, Colombia.
Hernandez JCP; Centro de Investigación, Clínica de la Costa SAS, Barranquilla, Atlántico, Colombia.
Quast AAF; Centro de Investigación, Clínica de la Costa SAS, Barranquilla, Atlántico, Colombia.
De Barros JAC; Centro de Investigación, Clínica de la Costa SAS, Barranquilla, Atlántico, Colombia.
Mejía JF; Centro de Investigación, Clínica de la Costa SAS, Barranquilla, Atlántico, Colombia.
Ruiz JP; Centro de Investigación, Clínica de la Costa SAS, Barranquilla, Atlántico, Colombia.
Boyle D; Department of Medicine, UC San Diego School of Medicine, San Diego, CA, United States of America.
Firestein GS; Department of Medicine, UC San Diego School of Medicine, San Diego, CA, United States of America.
Simon GL; Department of Medicine, George Washington University, Washington, DC, United States of America.
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Źródło:
PloS one [PLoS One] 2024 Mar 20; Vol. 19 (3), pp. e0299521. Date of Electronic Publication: 2024 Mar 20 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Chikungunya Fever*/complications
Arthritis, Infectious*
Humans ; Cytokines/metabolism ; Interleukin-10/metabolism ; Cross-Sectional Studies ; Interleukin-2/metabolism ; Interleukin-6/metabolism ; T-Lymphocytes, Regulatory/metabolism ; CD4-Positive T-Lymphocytes/metabolism ; Tumor Necrosis Factor-alpha/metabolism ; Immunosuppressive Agents
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Role of beta-(1→3)(1→6)-D-glucan derived from yeast on natural killer (NK) cells and breast cancer cell lines in 2D and 3D cultures.
Autorzy:
Boulifa A; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Charitéplatz 1, Berlin, 10117, Germany.; Competence Center of Immuno-Oncology and Translational Cell Therapy (KITZ), Department of Hematology, Oncology and Tumor Immunology, CCM, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, Berlin, 10117, Germany.
Raftery MJ; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Charitéplatz 1, Berlin, 10117, Germany.; Competence Center of Immuno-Oncology and Translational Cell Therapy (KITZ), Department of Hematology, Oncology and Tumor Immunology, CCM, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, Berlin, 10117, Germany.
Franzén AS; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Charitéplatz 1, Berlin, 10117, Germany.; Competence Center of Immuno-Oncology and Translational Cell Therapy (KITZ), Department of Hematology, Oncology and Tumor Immunology, CCM, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, Berlin, 10117, Germany.
Radecke C; Competence Center of Immuno-Oncology and Translational Cell Therapy (KITZ), Department of Hematology, Oncology and Tumor Immunology, CCM, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, Berlin, 10117, Germany.
Stintzing S; Competence Center of Immuno-Oncology and Translational Cell Therapy (KITZ), Department of Hematology, Oncology and Tumor Immunology, CCM, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, Berlin, 10117, Germany.
Blohmer JU; Department of Gynecology with Breast Center Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, Berlin, 10117, Germany.
Pecher G; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Charitéplatz 1, Berlin, 10117, Germany. .; Competence Center of Immuno-Oncology and Translational Cell Therapy (KITZ), Department of Hematology, Oncology and Tumor Immunology, CCM, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, Berlin, 10117, Germany. .
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Źródło:
BMC cancer [BMC Cancer] 2024 Mar 14; Vol. 24 (1), pp. 339. Date of Electronic Publication: 2024 Mar 14.
Typ publikacji:
Journal Article
MeSH Terms:
Breast Neoplasms*/pathology
beta-Glucans*/pharmacology
Humans ; Female ; MCF-7 Cells ; Glucans/pharmacology ; Saccharomyces cerevisiae ; Interleukin-2 ; Killer Cells, Natural
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A single-agent fusion of human IL-2 and anti-IL-2 antibody that selectively expands regulatory T cells.
Autorzy:
Lin Y; Shanghai Shengdi Pharmaceutical Co. Ltd, Shanghai, 200100, China.; Jiangsu Hengrui Pharmaceutical Co. Ltd, Lianyungang, 222000, China.
Wang X; Shanghai Shengdi Pharmaceutical Co. Ltd, Shanghai, 200100, China.; Jiangsu Hengrui Pharmaceutical Co. Ltd, Lianyungang, 222000, China.
Qin Y; Shanghai Shengdi Pharmaceutical Co. Ltd, Shanghai, 200100, China.; Jiangsu Hengrui Pharmaceutical Co. Ltd, Lianyungang, 222000, China.
Wang C; Shanghai Shengdi Pharmaceutical Co. Ltd, Shanghai, 200100, China.; Jiangsu Hengrui Pharmaceutical Co. Ltd, Lianyungang, 222000, China.
Zhou T; Shanghai Shengdi Pharmaceutical Co. Ltd, Shanghai, 200100, China.; Jiangsu Hengrui Pharmaceutical Co. Ltd, Lianyungang, 222000, China.
Zhang L; Shanghai Shengdi Pharmaceutical Co. Ltd, Shanghai, 200100, China.; Jiangsu Hengrui Pharmaceutical Co. Ltd, Lianyungang, 222000, China.
Su L; Shanghai Shengdi Pharmaceutical Co. Ltd, Shanghai, 200100, China.; Jiangsu Hengrui Pharmaceutical Co. Ltd, Lianyungang, 222000, China.
Ren W; Shanghai Shengdi Pharmaceutical Co. Ltd, Shanghai, 200100, China.; Jiangsu Hengrui Pharmaceutical Co. Ltd, Lianyungang, 222000, China.
Liao C; Shanghai Shengdi Pharmaceutical Co. Ltd, Shanghai, 200100, China. .; Jiangsu Hengrui Pharmaceutical Co. Ltd, Lianyungang, 222000, China. .
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Źródło:
Communications biology [Commun Biol] 2024 Mar 09; Vol. 7 (1), pp. 299. Date of Electronic Publication: 2024 Mar 09.
Typ publikacji:
Journal Article
MeSH Terms:
Lupus Erythematosus, Systemic*/drug therapy
Lupus Erythematosus, Systemic*/therapy
T-Lymphocytes, Regulatory*
Antibodies*/pharmacology
Antibodies*/therapeutic use
Animals ; Humans ; Autoimmune Diseases/drug therapy ; Autoimmune Diseases/therapy ; Cytokines ; Interleukin-2/immunology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Interleukin-2/anti-interleukin-2 immune complex attenuates cold ischemia-reperfusion injury after kidney transplantation by increasing renal regulatory T cells.
Autorzy:
Jang JY; Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
Kim HW; Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
Yan JJ; Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
Kang TK; Natural Product Research Center, Korea Institute of Science and Technology, Gangneung, Republic of Korea.
Lee WB; Natural Product Research Center, Korea Institute of Science and Technology, Gangneung, Republic of Korea.
Kim BS; Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
Yang J; Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
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Źródło:
Clinical and translational medicine [Clin Transl Med] 2024 Mar; Vol. 14 (3), pp. e1631.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Kidney Transplantation*/adverse effects
Reperfusion Injury*/drug therapy
Reperfusion Injury*/metabolism
Acute Kidney Injury*/drug therapy
Acute Kidney Injury*/etiology
Acute Kidney Injury*/metabolism
Animals ; Mice ; Interleukin-2/metabolism ; T-Lymphocytes, Regulatory ; Antigen-Antibody Complex ; Antioxidants/pharmacology ; Reactive Oxygen Species/metabolism ; Kidney ; Fibrosis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Associations between Th1-related cytokines and complicated pediatric appendicitis.
Autorzy:
Elliver M; Department of Clinical Sciences in Lund, Lund University, Lund, Sweden. .
Salö M; Department of Clinical Sciences in Lund, Lund University, Lund, Sweden.; Department of Pediatric Surgery, Skåne University Hospital, Lund, Sweden.
Roth B; Department of Clinical Sciences in Malmö, Lund University, Lund, Sweden.; Department of Internal Medicine, Skåne University Hospital, Malmö, Sweden.
Ohlsson B; Department of Clinical Sciences in Malmö, Lund University, Lund, Sweden.; Department of Internal Medicine, Skåne University Hospital, Malmö, Sweden.
Hagander L; Department of Clinical Sciences in Lund, Lund University, Lund, Sweden.; Department of Pediatric Surgery, Skåne University Hospital, Lund, Sweden.
Gudjonsdottir J; Department of Clinical Sciences in Lund, Lund University, Lund, Sweden.; Department of Surgery, Skåne University Hospital, Malmö, Sweden.
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Źródło:
Scientific reports [Sci Rep] 2024 Feb 26; Vol. 14 (1), pp. 4613. Date of Electronic Publication: 2024 Feb 26.
Typ publikacji:
Journal Article
MeSH Terms:
Cytokines*
Appendicitis*/complications
Male ; Humans ; Child ; Female ; Interleukin-10 ; Interleukin-17 ; Interleukin-6 ; Interleukin-2 ; Lymphotoxin-alpha ; Prospective Studies ; Interleukin-1beta
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The effects of low-dose IL-2 on Th17/Treg cell imbalance in primary biliary cholangitis mouse models.
Autorzy:
Wang Z; Beijing Key Laboratory of Hepatitis C and Immunotherapy for Liver Diseases, Peking University People's Hospital, Peking University Hepatology Institute, Beijing International Cooperation Base for Science and Technology on NAFLD Diagnosis, Beijing, China.
Liu Z; Beijing Key Laboratory of Hepatitis C and Immunotherapy for Liver Diseases, Peking University People's Hospital, Peking University Hepatology Institute, Beijing International Cooperation Base for Science and Technology on NAFLD Diagnosis, Beijing, China.
Zheng J; Beijing Key Laboratory of Hepatitis C and Immunotherapy for Liver Diseases, Peking University People's Hospital, Peking University Hepatology Institute, Beijing International Cooperation Base for Science and Technology on NAFLD Diagnosis, Beijing, China.
Huang L; Beijing Key Laboratory of Hepatitis C and Immunotherapy for Liver Diseases, Peking University People's Hospital, Peking University Hepatology Institute, Beijing International Cooperation Base for Science and Technology on NAFLD Diagnosis, Beijing, China.
Jin R; Beijing Key Laboratory of Hepatitis C and Immunotherapy for Liver Diseases, Peking University People's Hospital, Peking University Hepatology Institute, Beijing International Cooperation Base for Science and Technology on NAFLD Diagnosis, Beijing, China.
Wang X; Beijing Key Laboratory of Hepatitis C and Immunotherapy for Liver Diseases, Peking University People's Hospital, Peking University Hepatology Institute, Beijing International Cooperation Base for Science and Technology on NAFLD Diagnosis, Beijing, China.
Chen D; Beijing Key Laboratory of Hepatitis C and Immunotherapy for Liver Diseases, Peking University People's Hospital, Peking University Hepatology Institute, Beijing International Cooperation Base for Science and Technology on NAFLD Diagnosis, Beijing, China.
Xie Y; Beijing Key Laboratory of Hepatitis C and Immunotherapy for Liver Diseases, Peking University People's Hospital, Peking University Hepatology Institute, Beijing International Cooperation Base for Science and Technology on NAFLD Diagnosis, Beijing, China. .
Feng B; Beijing Key Laboratory of Hepatitis C and Immunotherapy for Liver Diseases, Peking University People's Hospital, Peking University Hepatology Institute, Beijing International Cooperation Base for Science and Technology on NAFLD Diagnosis, Beijing, China. .
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Źródło:
BMC gastroenterology [BMC Gastroenterol] 2024 Feb 26; Vol. 24 (1), pp. 87. Date of Electronic Publication: 2024 Feb 26.
Typ publikacji:
Journal Article
MeSH Terms:
T-Lymphocytes, Regulatory*
Liver Cirrhosis, Biliary*/drug therapy
Humans ; Mice ; Animals ; Female ; Th17 Cells/pathology ; Interleukin-2 ; Mice, Inbred C57BL
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Comparison of IL-2-antibody to IL-2-Fc with or without stereotactic radiation therapy in CEA immunocompetent mice with CEA positive tumors.
Autorzy:
Williams L; Department of Immunology and Theranostics, Riggs Diabetes, Metabolism, and Research Institute, Beckman Research Institute of City of Hope, Duarte, California, USA.
Li L; Department of Immunology and Theranostics, Riggs Diabetes, Metabolism, and Research Institute, Beckman Research Institute of City of Hope, Duarte, California, USA.
Yazaki PJ; Department of Immunology and Theranostics, Riggs Diabetes, Metabolism, and Research Institute, Beckman Research Institute of City of Hope, Duarte, California, USA.
Wong P; Department of Immunology and Theranostics, Riggs Diabetes, Metabolism, and Research Institute, Beckman Research Institute of City of Hope, Duarte, California, USA.
Hong T; Department of Immunology and Theranostics, Riggs Diabetes, Metabolism, and Research Institute, Beckman Research Institute of City of Hope, Duarte, California, USA.
Poku EK; Radiopharmacy, City of Hope, Duarte, California, USA.; Beckman Research Institute of City of Hope, Duarte, California, USA.
Hui S; Department of Radiation Oncology, City of Hope, Duarte, California, USA.; City of Hope Medical Center, Duarte, California, USA.
Ghimire H; Department of Radiation Oncology, City of Hope, Duarte, California, USA.; City of Hope Medical Center, Duarte, California, USA.
Shively JE; Department of Immunology and Theranostics, Riggs Diabetes, Metabolism, and Research Institute, Beckman Research Institute of City of Hope, Duarte, California, USA.
Kujawski M; Department of Immunology and Theranostics, Riggs Diabetes, Metabolism, and Research Institute, Beckman Research Institute of City of Hope, Duarte, California, USA.
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Źródło:
Cancer medicine [Cancer Med] 2024 Feb; Vol. 13 (3), pp. e6909. Date of Electronic Publication: 2024 Feb 05.
Typ publikacji:
Journal Article
MeSH Terms:
Radiosurgery*
Neoplasms*/therapy
Mice ; Animals ; Interleukin-2/pharmacology ; CD8-Positive T-Lymphocytes ; Antibodies ; Mice, Transgenic
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Regulation of Cx43 Gap Junction Intercellular Communication by Bruton's Tyrosine Kinase and Interleukin-2-Inducible T-Cell Kinase.
Autorzy:
Basu I; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Li H; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Trease AJ; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Sorgen PL; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE 68198, USA.
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Źródło:
Biomolecules [Biomolecules] 2023 Apr 08; Vol. 13 (4). Date of Electronic Publication: 2023 Apr 08.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Interleukin-2*/metabolism
Connexin 43*/genetics
Connexin 43*/metabolism
Humans ; Agammaglobulinaemia Tyrosine Kinase/metabolism ; Focal Adhesion Kinase 2 ; Cell Communication/physiology ; Phosphorylation ; Gap Junctions/metabolism ; Receptors, Antigen, B-Cell/metabolism ; Tyrosine/metabolism ; T-Lymphocytes/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
IL-2-based approaches to Treg enhancement.
Autorzy:
Harris F; Department of Immunobiology, Faculty of Life Sciences and Medicine, King's College, London, UK.
Berdugo YA; Department of Immunobiology, Faculty of Life Sciences and Medicine, King's College, London, UK.
Tree T; Department of Immunobiology, Faculty of Life Sciences and Medicine, King's College, London, UK.; National Institute of Health Research Biomedical Research Centre at Guy's and St. Thomas' National Health Service Foundation Trust, King's College London, London, UK.
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Źródło:
Clinical and experimental immunology [Clin Exp Immunol] 2023 Mar 16; Vol. 211 (2), pp. 149-163.
Typ publikacji:
Review; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Interleukin-2*/therapeutic use
Autoimmune Diseases*/genetics
Humans ; T-Lymphocytes, Regulatory ; Cytokines ; Immunotherapy
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
GRB2 dimerization mediated by SH2 domain-swapping is critical for T cell signaling and cytokine production.
Autorzy:
Sandouk A; Interdisciplinary Graduate Program in Immunology, University of Iowa, Iowa City, IA, 52242, USA.
Xu Z; Protein and Crystallography Facility, University of Iowa, Iowa City, IA, 52242, USA.
Baruah S; Protein and Crystallography Facility, University of Iowa, Iowa City, IA, 52242, USA.
Tremblay M; Department of Microbiology and Immunology, University of Iowa, Iowa City, IA, 52242, USA.
Hopkins JB; Biophysics Collaborative Access Team, Argonne National Laboratory, Argonne, IL, 60439, USA.
Chakravarthy S; Biophysics Collaborative Access Team, Argonne National Laboratory, Argonne, IL, 60439, USA.
Gakhar L; Protein and Crystallography Facility, University of Iowa, Iowa City, IA, 52242, USA.; Department of Biochemistry and Molecular Biology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA, 52242, USA.
Schnicker NJ; Protein and Crystallography Facility, University of Iowa, Iowa City, IA, 52242, USA.
Houtman JCD; Interdisciplinary Graduate Program in Immunology, University of Iowa, Iowa City, IA, 52242, USA. .; Department of Microbiology and Immunology, University of Iowa, Iowa City, IA, 52242, USA. .
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Źródło:
Scientific reports [Sci Rep] 2023 Mar 02; Vol. 13 (1), pp. 3505. Date of Electronic Publication: 2023 Mar 02.
Typ publikacji:
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural
MeSH Terms:
src Homology Domains*
Interleukin-2*
Humans ; Dimerization ; Scattering, Small Angle ; T-Lymphocytes ; X-Ray Diffraction ; Signal Transduction ; Adaptor Proteins, Signal Transducing/genetics ; Polymers ; GRB2 Adaptor Protein/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Incubation of Lymphocytes with IL-2 Causes the Appearance of Antitumor T Cells Carrying FC, CD25, and LFA-1 on the Surface.
Autorzy:
Ivanova OK; Institute of Gene Biology of the Russian Academy of Sciences, Moscow, Russia. .
Sharapova TN; Institute of Gene Biology of the Russian Academy of Sciences, Moscow, Russia.
Romanova EA; Institute of Gene Biology of the Russian Academy of Sciences, Moscow, Russia.
Yashin DV; Institute of Gene Biology of the Russian Academy of Sciences, Moscow, Russia.
Sashchenko LP; Institute of Gene Biology of the Russian Academy of Sciences, Moscow, Russia.
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Źródło:
Doklady. Biochemistry and biophysics [Dokl Biochem Biophys] 2023 Feb; Vol. 508 (1), pp. 12-16. Date of Electronic Publication: 2023 Jan 18.
Typ publikacji:
Journal Article
MeSH Terms:
Interleukin-2*/metabolism
Lymphocyte Function-Associated Antigen-1*/metabolism
Humans ; Apoptosis ; CD8-Positive T-Lymphocytes ; Cytokines ; T-Lymphocytes/immunology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Synthetic cytokine circuits that drive T cells into immune-excluded tumors.
Autorzy:
Allen GM; Cell Design Institute; University of California San Francisco, San Francisco, CA 94158, USA.; Department of Medicine, University of California San Francisco; San Francisco, CA 94158, USA.
Frankel NW; Cell Design Institute; University of California San Francisco, San Francisco, CA 94158, USA.; Department of Cellular and Molecular Pharmacology, University of California San Francisco; San Francisco, CA 94158, USA.
Reddy NR; Cell Design Institute; University of California San Francisco, San Francisco, CA 94158, USA.; Department of Cellular and Molecular Pharmacology, University of California San Francisco; San Francisco, CA 94158, USA.
Bhargava HK; Cell Design Institute; University of California San Francisco, San Francisco, CA 94158, USA.; Biophysics Graduate Program, University of California San Francisco; San Francisco, CA 94158, USA.
Yoshida MA; Cell Design Institute; University of California San Francisco, San Francisco, CA 94158, USA.; Department of Cellular and Molecular Pharmacology, University of California San Francisco; San Francisco, CA 94158, USA.
Stark SR; Cell Design Institute; University of California San Francisco, San Francisco, CA 94158, USA.; Department of Cellular and Molecular Pharmacology, University of California San Francisco; San Francisco, CA 94158, USA.
Purl M; Cell Design Institute; University of California San Francisco, San Francisco, CA 94158, USA.; Department of Cellular and Molecular Pharmacology, University of California San Francisco; San Francisco, CA 94158, USA.
Lee J; Cell Design Institute; University of California San Francisco, San Francisco, CA 94158, USA.; Department of Cellular and Molecular Pharmacology, University of California San Francisco; San Francisco, CA 94158, USA.
Yee JL; Department of Microbiology and Immunology, University of California San Francisco; San Francisco, CA 94158, USA.
Yu W; Cell Design Institute; University of California San Francisco, San Francisco, CA 94158, USA.; Department of Cellular and Molecular Pharmacology, University of California San Francisco; San Francisco, CA 94158, USA.
Li AW; Cell Design Institute; University of California San Francisco, San Francisco, CA 94158, USA.; Department of Cellular and Molecular Pharmacology, University of California San Francisco; San Francisco, CA 94158, USA.
Garcia KC; Department of Molecular and Cellular Physiology and Structural Biology, Howard Hughes Medical Institute, Stanford University; Stanford, USA.
El-Samad H; Cell Design Institute; University of California San Francisco, San Francisco, CA 94158, USA.; Department of Biochemistry and Biophysics, University of California San Francisco; San Francisco, CA 94158, USA.
Roybal KT; Cell Design Institute; University of California San Francisco, San Francisco, CA 94158, USA.; Department of Microbiology and Immunology, University of California San Francisco; San Francisco, CA 94158, USA.; Parker Institute for Cancer Immunotherapy, University of California San Francisco; San Francisco, CA 94158, USA.
Spitzer MH; Department of Microbiology and Immunology, University of California San Francisco; San Francisco, CA 94158, USA.; Parker Institute for Cancer Immunotherapy, University of California San Francisco; San Francisco, CA 94158, USA.; Department of Otolaryngology-Head and Neck Surgery, University of California San Francisco; San Francisco, CA 94158, USA.
Lim WA; Cell Design Institute; University of California San Francisco, San Francisco, CA 94158, USA.; Department of Cellular and Molecular Pharmacology, University of California San Francisco; San Francisco, CA 94158, USA.; Department of Biochemistry and Biophysics, University of California San Francisco; San Francisco, CA 94158, USA.; Parker Institute for Cancer Immunotherapy, University of California San Francisco; San Francisco, CA 94158, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2022 Dec 16; Vol. 378 (6625), pp. eaba1624. Date of Electronic Publication: 2022 Dec 16.
Typ publikacji:
Journal Article
MeSH Terms:
Immunotherapy, Adoptive*/methods
Interleukin-2*/genetics
Interleukin-2*/metabolism
Neoplasms*/immunology
Neoplasms*/therapy
T-Lymphocytes*/immunology
T-Lymphocytes*/transplantation
Receptors, Chimeric Antigen*/genetics
Receptors, Chimeric Antigen*/metabolism
Immunosuppression Therapy*/methods
Humans ; Receptors, Antigen, T-Cell/genetics ; Tumor Microenvironment ; Animals ; Mice ; Cell Engineering ; Receptors, Notch/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Pro- and Anti-Tumoral Factors Involved in Total Body Irradiation and Interleukin-2 Conditioning in Adoptive T Cell Therapy of Melanoma-Bearing Rag1 Knock-Out Mice.
Autorzy:
Kim SH; Immuno-Oncology Branch, Division of Rare and Refractory Cancer, Research Institute, National Cancer Center, Goyang 10408, Republic of Korea.; Department of Biomedical Laboratory Science, Catholic Kwandong University, Gangneung 25601, Republic of Korea.
Go EM; Immuno-Oncology Branch, Division of Rare and Refractory Cancer, Research Institute, National Cancer Center, Goyang 10408, Republic of Korea.
Shin DH; Targeted Therapy Branch, Division of Rare and Refractory Cancer, Research Institute, National Cancer Center, Goyang 10408, Republic of Korea.; Department of Cancer Biomedical Science, Graduate School of Cancer Science and Policy, National Cancer Center, Goyang 10408, Republic of Korea.
Choi BK; Biomedicine Production Branch, Cancer Immunotherapy Working Group, Research Institute, National Cancer Center, Goyang 10408, Republic of Korea.
Han C; Immuno-Oncology Branch, Division of Rare and Refractory Cancer, Research Institute, National Cancer Center, Goyang 10408, Republic of Korea.; Department of Cancer Biomedical Science, Graduate School of Cancer Science and Policy, National Cancer Center, Goyang 10408, Republic of Korea.
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Źródło:
Cells [Cells] 2022 Dec 02; Vol. 11 (23). Date of Electronic Publication: 2022 Dec 02.
Typ publikacji:
Journal Article
MeSH Terms:
Immunotherapy, Adoptive*
Interleukin-2*/pharmacology
Melanoma*/therapy
Animals ; Mice ; Cell- and Tissue-Based Therapy ; Mice, Knockout ; Whole-Body Irradiation ; T-Lymphocytes
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Development of Innate-Immune-Cell-Based Immunotherapy for Adult T-Cell Leukemia-Lymphoma.
Autorzy:
Nakashima M; Department of Dermatology, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki 852-8501, Japan.
Tanaka Y; Center for Medical Innovation, Nagasaki University, Nagasaki 852-8588, Japan.
Okamura H; Department of Tumor Cell Therapy, Hyogo College of Medicine, Nishinomiya 663-8501, Japan.
Kato T; Department of Hematology, Nagasaki University Hospital, Nagasaki 852-8501, Japan.
Imaizumi Y; Department of Hematology, National Hospital Organization Nagasaki Medical Center, Omura 856-8562, Japan.
Nagai K; Department of Clinical Laboratory, National Hospital Organization Nagasaki Medical Center, Omura 856-8562, Japan.
Miyazaki Y; Department of Hematology, Atomic Bomb Disease Institute, Nagasaki University, Nagasaki 852-8523, Japan.
Murota H; Department of Dermatology, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki 852-8501, Japan.; Leading Medical Research Core Unit, Life Science Innovation, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8521, Japan.
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Źródło:
Cells [Cells] 2024 Jan 10; Vol. 13 (2). Date of Electronic Publication: 2024 Jan 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Leukemia-Lymphoma, Adult T-Cell*/therapy
Human T-lymphotropic virus 1*
Adult ; Aged ; Humans ; Interleukin-18 ; Interleukin-2 ; Leukocytes, Mononuclear ; Immunotherapy ; Antibodies, Monoclonal
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Changes in serum levels of pain mediators in hemiplegic shoulder pain.
Autorzy:
Lei M; Rehabilitation Center, The first Affiliated Hospital with Nanjing Medical University, Nanjing, China.; Children's Hospital Affiliated to Zhejiang University School of Medicine, Hangzhou, China.
Wang Y; Department of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing, China.
Chen Q; Department of Rehabilitation Medicine, Nanjing Qixia District Hospital, Nanjing, China.
Huang P; Department of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing, China.
Li Y; The Second Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Jia Y; Rehabilitation Center, The first Affiliated Hospital with Nanjing Medical University, Nanjing, China.
Meng D; Rehabilitation Center, The first Affiliated Hospital with Nanjing Medical University, Nanjing, China.
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Źródło:
Brain and behavior [Brain Behav] 2023 Dec; Vol. 13 (12), pp. e3289. Date of Electronic Publication: 2023 Oct 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Shoulder Pain*/therapy
Stroke*
Humans ; Interleukin-10 ; Calcitonin Gene-Related Peptide ; Tumor Necrosis Factor-alpha ; Nerve Growth Factor ; Dinoprostone ; Hemiplegia ; Cross-Sectional Studies ; Interleukin-2 ; Interleukin-6 ; Serotonin
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Sustaining the T-cell activity in xenografted psoriasis skin.
Autorzy:
Christensen PKF; LEO Pharma A/S, Ballerup, Denmark.; Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg C, Denmark.
Hansen AK; Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg C, Denmark.
Skov S; Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg C, Denmark.
Engkilde K; Amniotics AB, Lund, Sweden.
Larsen J; Bioneer A/S, Hørsholm, Denmark.
Høyer-Hansen MH; LEO Pharma A/S, Ballerup, Denmark.
Koch J; LEO Pharma A/S, Ballerup, Denmark.
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Źródło:
PloS one [PLoS One] 2023 Jan 17; Vol. 18 (1), pp. e0278390. Date of Electronic Publication: 2023 Jan 17 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Interleukin-2*
Psoriasis*/pathology
Humans ; Mice ; Animals ; Transplantation, Heterologous ; T-Lymphocytes/pathology ; Skin/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Proton-Pump Inhibitors Suppress T Cell Response by Shifting Intracellular Zinc Distribution.
Autorzy:
Liu W; Institute of Immunology, Faculty of Medicine, RWTH Aachen University Hospital, Pauwelsstraße 30, 52074 Aachen, Germany.
Jakobs J; Institute of Immunology, Faculty of Medicine, RWTH Aachen University Hospital, Pauwelsstraße 30, 52074 Aachen, Germany.
Rink L; Institute of Immunology, Faculty of Medicine, RWTH Aachen University Hospital, Pauwelsstraße 30, 52074 Aachen, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jan 07; Vol. 24 (2). Date of Electronic Publication: 2023 Jan 07.
Typ publikacji:
Journal Article
MeSH Terms:
Proton Pump Inhibitors*/pharmacology
Interleukin-2*
Pantoprazole/pharmacology ; 2-Pyridinylmethylsulfinylbenzimidazoles/pharmacology ; Zinc/pharmacology ; T-Lymphocytes ; Acids
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Absolute decrease in regulatory T cells and low-dose interleukin-2 therapy: restoring and expanding regulatory T cells to treat systemic sclerosis: a 24-week study.
Autorzy:
Yu Z; Department of Rheumatology, Shanxi Medical University Second Affiliated Hospital, Taiyuan, China.
Cheng H; Department of Rheumatology, Shanxi Medical University Second Affiliated Hospital, Taiyuan, China.
Ding T; Department of Rheumatology, Shanxi Medical University Second Affiliated Hospital, Taiyuan, China.
Liang Y; Department of Rheumatology, Shanxi Medical University Second Affiliated Hospital, Taiyuan, China.
Yan C; Department of Rheumatology, Shanxi Medical University Second Affiliated Hospital, Taiyuan, China.
Gao C; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Wen H; Department of Rheumatology, Shanxi Medical University Second Affiliated Hospital, Taiyuan, China.
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Źródło:
Clinical and experimental dermatology [Clin Exp Dermatol] 2022 Dec; Vol. 47 (12), pp. 2188-2195. Date of Electronic Publication: 2022 Oct 02.
Typ publikacji:
Journal Article
MeSH Terms:
Interleukin-2*/therapeutic use
Scleroderma, Systemic*/drug therapy
T-Lymphocytes, Regulatory*
Humans ; T-Lymphocyte Subsets ; Th17 Cells
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Diversity-Oriented Synthesis of a Molecular Library of Immunomodulatory α-Galactosylceramides with Fluorous-Tag-Assisted Purification and Evaluation of Their Bioactivities in Regard to IL-2 Secretion.
Autorzy:
Chen YN; Department of Chemistry, National Tsing Hua University, Hsinchu 30044, Taiwan.
Hung JT; Institute of Stem Cell and Translational Cancer Research, Chang Gung Memorial Hospital, and Chang Gung University, Linkou, Taoyuan 33302, Taiwan.
Jan FD; Department of Chemistry, National Tsing Hua University, Hsinchu 30044, Taiwan.
Su YY; Department of Chemistry, National Tsing Hua University, Hsinchu 30044, Taiwan.
Hwu JR; Department of Chemistry, National Tsing Hua University, Hsinchu 30044, Taiwan.
Yu AL; Institute of Stem Cell and Translational Cancer Research, Chang Gung Memorial Hospital, and Chang Gung University, Linkou, Taoyuan 33302, Taiwan.; Department of Pediatrics, University of California, San Diego, CA 92093, USA.
Adak AK; Department of Chemistry, National Tsing Hua University, Hsinchu 30044, Taiwan.
Lin CC; Department of Chemistry, National Tsing Hua University, Hsinchu 30044, Taiwan.; Department of Medicinal and Applied Chemistry, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Nov 02; Vol. 23 (21). Date of Electronic Publication: 2022 Nov 02.
Typ publikacji:
Journal Article
MeSH Terms:
Interleukin-2*
Natural Killer T-Cells*
Mice ; Animals ; Antigens, CD1d ; Glycolipids/pharmacology ; Fatty Acids
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 21-40 z 29412

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