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Tytuł:
IL-4Rα signalling in B cells and T cells play differential roles in acute and chronic atopic dermatitis.
Autorzy:
Scibiorek M; Division of Immunology, Department of Pathology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa. .; Division of Immunology, International Centre for Genetic Engineering and Biotechnology (ICGEB), Institute of Infectious Diseases and Molecular Medicine (IDM), Health Science Faculty, University of Cape Town, Cape Town, South Africa. .
Mthembu N; Division of Immunology, Department of Pathology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa. .
Mangali S; Division of Immunology, Department of Pathology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.; Division of Immunology, International Centre for Genetic Engineering and Biotechnology (ICGEB), Institute of Infectious Diseases and Molecular Medicine (IDM), Health Science Faculty, University of Cape Town, Cape Town, South Africa.
Ngomti A; Division of Immunology, Department of Pathology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Ikwegbue P; Division of Immunology, Department of Pathology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Brombacher F; Division of Immunology, Department of Pathology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.; Division of Immunology, International Centre for Genetic Engineering and Biotechnology (ICGEB), Institute of Infectious Diseases and Molecular Medicine (IDM), Health Science Faculty, University of Cape Town, Cape Town, South Africa.; Wellcome Centre for Infectious Diseases Research in Africa (CIDRI-Africa), Institute of Infectious Diseases and Molecular Medicine (IDM), Faculty of Health Sciences, University of Cape Town, Cape Town, 7925, South Africa.
Hadebe S; Division of Immunology, Department of Pathology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa. .
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Źródło:
Scientific reports [Sci Rep] 2023 Jan 04; Vol. 13 (1), pp. 144. Date of Electronic Publication: 2023 Jan 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
B-Lymphocytes*/metabolism
B-Lymphocytes*/pathology
Dermatitis, Atopic*/metabolism
Dermatitis, Atopic*/pathology
Interleukin-4 Receptor alpha Subunit*/metabolism
Th2 Cells*/metabolism
Th2 Cells*/pathology
Animals ; Mice ; Allergens/adverse effects ; Immunoglobulin E/blood ; Immunoglobulin E/chemistry ; Mice, Inbred BALB C ; Mice, Knockout ; Receptors, Interleukin-4/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Apoptotic cell identity induces distinct functional responses to IL-4 in efferocytic macrophages.
Autorzy:
Liebold I; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Protozoa Immunology, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.
Al Jawazneh A; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Protozoa Immunology, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.
Casar C; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Bioinformatics Core, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.
Lanzloth C; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Protozoa Immunology, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.
Leyk S; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Protozoa Immunology, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.
Hamley M; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Protozoa Immunology, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.
Wong MN; III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Hamburg Center for Kidney Health (HCKH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.; Department of Pathology, Aarhus University Hospital, Aarhus, Denmark.
Kylies D; III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Hamburg Center for Kidney Health (HCKH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Gräfe SK; III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Hamburg Center for Kidney Health (HCKH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Edenhofer I; III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Hamburg Center for Kidney Health (HCKH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Aranda-Pardos I; Institute of Immunology, University of Münster, Münster, Germany.
Kriwet M; Institute of Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Haas H; helminGuard, Sülfeld/Borstel, Germany.
Krause J; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Hadjilaou A; Protozoa Immunology, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.; Institute of Neuroimmunology and Multiple Sclerosis, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Schromm AB; Division of Immunobiophysics, Research Center Borstel, Leibniz Lung Center, Borstel, Germany.
Richardt U; Protozoa Immunology, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.
Eggert P; Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.
Tappe D; Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.
Weidemann SA; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Ghosh S; Department of Neurology, Yale University School of Medicine, New Haven, CT, USA.; Department of Pharmacology, Yale University School of Medicine, New Haven, CT, USA.
Krebs CF; III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Hamburg Center for Translational Immunology (HCTI), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
A-Gonzalez N; Institute of Immunology, University of Münster, Münster, Germany.
Worthmann A; Department of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Lohse AW; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Hamburg Center for Translational Immunology (HCTI), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; European Reference Network on Hepatological Diseases (ERN-RARE LIVER), Hamburg, Germany.
Huber S; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Hamburg Center for Translational Immunology (HCTI), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Rothlin CV; Department of Pharmacology, Yale University School of Medicine, New Haven, CT, USA.; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
Puelles VG; III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Hamburg Center for Kidney Health (HCKH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.; Department of Pathology, Aarhus University Hospital, Aarhus, Denmark.
Jacobs T; Protozoa Immunology, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.
Gagliani N; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Hamburg Center for Translational Immunology (HCTI), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Bosurgi L; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Protozoa Immunology, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.; Hamburg Center for Translational Immunology (HCTI), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
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Źródło:
Science (New York, N.Y.) [Science] 2024 Apr 05; Vol. 384 (6691), pp. eabo7027. Date of Electronic Publication: 2024 Apr 05.
Typ publikacji:
Journal Article
MeSH Terms:
Interleukin-4*
Apoptosis*
Mice ; Animals ; Mice, Knockout ; Macrophages ; Phagocytosis ; Neutrophils
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Tyrosine Sulfation at Antibody Light Chain CDR-1 Increases Binding Affinity and Neutralization Potency to Interleukine-4.
Autorzy:
D'Antona AM; BioMedicine Design, Pfizer Research & Development, 610 Main Street, Cambridge, MA 02139, USA.
Lee JM; Translational Clinical Sciences, Pfizer Discovery & Early Development, 610 Main Street, Cambridge, MA 02139, USA.
Zhang M; Inflammation and Immunology Research Unit, Pfizer Research & Development, 610 Main Street, Cambridge, MA 02139, USA.
Friedman C; BioMedicine Design, Pfizer Research & Development, 610 Main Street, Cambridge, MA 02139, USA.
He T; BioMedicine Design, Pfizer Research & Development, 610 Main Street, Cambridge, MA 02139, USA.
Mosyak L; BioMedicine Design, Pfizer Research & Development, 610 Main Street, Cambridge, MA 02139, USA.
Bennett E; BioMedicine Design, Pfizer Research & Development, 610 Main Street, Cambridge, MA 02139, USA.
Lin L; BioMedicine Design, Pfizer Research & Development, 610 Main Street, Cambridge, MA 02139, USA.
Silverman M; BioMedicine Design, Pfizer Research & Development, 610 Main Street, Cambridge, MA 02139, USA.
Cometa F; BioMedicine Design, Pfizer Research & Development, 610 Main Street, Cambridge, MA 02139, USA.
Meade C; BioMedicine Design, Pfizer Research & Development, 610 Main Street, Cambridge, MA 02139, USA.
Hageman T; BioMedicine Design, Pfizer Research & Development, 610 Main Street, Cambridge, MA 02139, USA.
Sousa E; BioMedicine Design, Pfizer Research & Development, 610 Main Street, Cambridge, MA 02139, USA.
Cohen J; BioMedicine Design, Pfizer Research & Development, 610 Main Street, Cambridge, MA 02139, USA.
Marquette K; BioMedicine Design, Pfizer Research & Development, 610 Main Street, Cambridge, MA 02139, USA.
Ferguson D; BioMedicine Design, Pfizer Research & Development, 610 Main Street, Cambridge, MA 02139, USA.
Zhong X; BioMedicine Design, Pfizer Research & Development, 610 Main Street, Cambridge, MA 02139, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 05; Vol. 25 (3). Date of Electronic Publication: 2024 Feb 05.
Typ publikacji:
Journal Article
MeSH Terms:
Tyrosine*/metabolism
Interleukin-4*
Humans ; HEK293 Cells ; Golgi Apparatus/metabolism ; Mutagenesis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
PRMT2 silencing regulates macrophage polarization through activation of STAT1 or inhibition of STAT6.
Autorzy:
Liu T; Department of Anesthesiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.
Li Y; Department of Anesthesiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.
Xu M; Department of Anesthesiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.
Huang H; Department of Anesthesiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China. .
Luo Y; Department of Anesthesiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China. .
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Źródło:
BMC immunology [BMC Immunol] 2024 Jan 03; Vol. 25 (1), pp. 1. Date of Electronic Publication: 2024 Jan 03.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Interleukin-4*/metabolism
Lipopolysaccharides*/pharmacology
Lipopolysaccharides*/metabolism
Animals ; Mice ; Inflammation/metabolism ; Interferon-gamma/metabolism ; Macrophage Activation ; Macrophages ; Signal Transduction ; STAT6 Transcription Factor/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Elevated Serum Levels of Soluble Transferrin Receptor Are Associated with an Increased Risk of Cardiovascular, Pulmonary, and Hematological Manifestations and a Decreased Risk of Neuropsychiatric Manifestations in Systemic Lupus Erythematosus Patients.
Autorzy:
Winikajtis-Burzyńska A; Individual Laboratory for Rheumatologic Diagnostics, Pomeranian Medical University in Szczecin, Unii Lubelskiej 1, 71-252 Szczecin, Poland.
Brzosko M; Department of Rheumatology, Internal Medicine, Geriatrics and Clinical Immunology, Pomeranian Medical University in Szczecin, Unii Lubelskiej 1, 71-252 Szczecin, Poland.
Przepiera-Będzak H; Department of Rheumatology, Internal Medicine, Geriatrics and Clinical Immunology, Pomeranian Medical University in Szczecin, Unii Lubelskiej 1, 71-252 Szczecin, Poland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Dec 11; Vol. 24 (24). Date of Electronic Publication: 2023 Dec 11.
Typ publikacji:
Journal Article
MeSH Terms:
Interleukin-4*
Lupus Erythematosus, Systemic*
Humans ; Iron ; Receptors, Transferrin ; Interleukin-6 ; Lung
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Akt, IL-4, and STAT Proteins Play Distinct Roles in Prostaglandin Production in Human Follicular Dendritic Cell-like Cells.
Autorzy:
Jeong J; Interdisciplinary Graduate Program in BIT Medical Convergence, Department of Microbiology and Immunology, School of Medicine, Kangwon National University, Chuncheon 24341, Republic of Korea.
Choe J; Interdisciplinary Graduate Program in BIT Medical Convergence, Department of Microbiology and Immunology, School of Medicine, Kangwon National University, Chuncheon 24341, Republic of Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Nov 24; Vol. 24 (23). Date of Electronic Publication: 2023 Nov 24.
Typ publikacji:
Journal Article
MeSH Terms:
Dendritic Cells, Follicular*/metabolism
Interleukin-4*/metabolism
Humans ; Cells, Cultured ; Cyclooxygenase 2/metabolism ; Interleukin-1beta/metabolism ; Prostaglandins/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; STAT Transcription Factors/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The upregulation of peripheral CD3 natural killer cells correlates with Th1/Th2 imbalance in asthma patients during acute upper respiratory viral infections.
Autorzy:
Liu M; Department of Respiratory Medicine, Shanghai East Hospital, School of Medicine, Tongji University, 200123, Shanghai, China.
Zhang Y; Department of Pharmacy, Huadong Hospital, Fudan University, 200120, Shanghai, China.
Hu Y; Department of Respiratory Medicine, Shanghai East Hospital, School of Medicine, Tongji University, 200123, Shanghai, China.
Guo Z; Department of Respiratory Medicine, Shanghai East Hospital, School of Medicine, Tongji University, 200123, Shanghai, China. .
Dong L; Department of Thoracic Surgery, Shanghai East Hospital, School of Medicine, Tongji University, 200123, Shanghai, China. .
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Źródło:
BMC immunology [BMC Immunol] 2023 Oct 21; Vol. 24 (1), pp. 40. Date of Electronic Publication: 2023 Oct 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Interleukin-4*
Asthma*
Humans ; Up-Regulation ; Interleukin-5 ; Killer Cells, Natural ; Cytokines ; CD56 Antigen/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Proinflammatory IFNγ Is Produced by but Not Required for the Generation of Eomes Thymic Innate CD8 T Cells.
Autorzy:
Won HY; Experimental Immunology Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA.
Liman N; Experimental Immunology Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA.
Li C; Experimental Immunology Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA.
Park JH; Experimental Immunology Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA.
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Źródło:
Cells [Cells] 2023 Oct 11; Vol. 12 (20). Date of Electronic Publication: 2023 Oct 11.
Typ publikacji:
Journal Article; Research Support, N.I.H., Intramural
MeSH Terms:
Interleukin-4*
Thymus Gland*
Mice ; Animals ; CD8-Positive T-Lymphocytes ; Cytokines ; Mice, Transgenic ; Interferon-gamma ; T-Box Domain Proteins/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Choline metabolism underpins macrophage IL-4 polarization and RELMα up-regulation in helminth infection.
Autorzy:
Ghorbani P; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.; Centre for Infection, Immunity and Inflammation, University of Ottawa, Ottawa, Ontario, Canada.; Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, Ontario, Canada.
Kim SY; Division of Biomedical Sciences, School of Medicine, University of California Riverside, Riverside, California, United States of America.
Smith TKT; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.; Centre for Infection, Immunity and Inflammation, University of Ottawa, Ottawa, Ontario, Canada.; Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, Ontario, Canada.
Minarrieta L; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.; Centre for Infection, Immunity and Inflammation, University of Ottawa, Ottawa, Ontario, Canada.; Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, Ontario, Canada.
Robert-Gostlin V; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.; Centre for Infection, Immunity and Inflammation, University of Ottawa, Ottawa, Ontario, Canada.; Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, Ontario, Canada.
Kilgour MK; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.; Centre for Infection, Immunity and Inflammation, University of Ottawa, Ottawa, Ontario, Canada.
Ilijevska M; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.; Centre for Infection, Immunity and Inflammation, University of Ottawa, Ottawa, Ontario, Canada.
Alecu I; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.; Centre for Infection, Immunity and Inflammation, University of Ottawa, Ottawa, Ontario, Canada.; Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, Ontario, Canada.
Snider SA; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.
Margison KD; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.
Nunes JRC; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.; Centre for Infection, Immunity and Inflammation, University of Ottawa, Ottawa, Ontario, Canada.; Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, Ontario, Canada.
Woo D; Division of Biomedical Sciences, School of Medicine, University of California Riverside, Riverside, California, United States of America.
Pember C; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.; Centre for Infection, Immunity and Inflammation, University of Ottawa, Ottawa, Ontario, Canada.
O'Dwyer C; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.; Centre for Infection, Immunity and Inflammation, University of Ottawa, Ottawa, Ontario, Canada.; Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, Ontario, Canada.
Ouellette J; Neuroscience Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.
Kotchetkov P; Neuroscience Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.
St-Pierre J; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.; Centre for Infection, Immunity and Inflammation, University of Ottawa, Ottawa, Ontario, Canada.; Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, Ontario, Canada.
Bennett SAL; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.; Centre for Infection, Immunity and Inflammation, University of Ottawa, Ottawa, Ontario, Canada.; Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, Ontario, Canada.; Centre for Catalysis Research and Innovation, University of Ottawa, Ottawa, Ontario, Canada.; University of Ottawa Brain and Mind Institute, University of Ottawa, Ottawa, Ontario, Canada.
Lacoste B; Neuroscience Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.; University of Ottawa Brain and Mind Institute, University of Ottawa, Ottawa, Ontario, Canada.
Blais A; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.; Centre for Infection, Immunity and Inflammation, University of Ottawa, Ottawa, Ontario, Canada.; Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, Ontario, Canada.; University of Ottawa Brain and Mind Institute, University of Ottawa, Ottawa, Ontario, Canada.; Éric Poulin Centre for Neuromuscular Disease, Ottawa, Ontario, Canada.
Nair MG; Division of Biomedical Sciences, School of Medicine, University of California Riverside, Riverside, California, United States of America.
Fullerton MD; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.; Centre for Infection, Immunity and Inflammation, University of Ottawa, Ottawa, Ontario, Canada.; Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, Ontario, Canada.; Centre for Catalysis Research and Innovation, University of Ottawa, Ottawa, Ontario, Canada.
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Źródło:
PLoS pathogens [PLoS Pathog] 2023 Sep 25; Vol. 19 (9), pp. e1011658. Date of Electronic Publication: 2023 Sep 25 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Interleukin-4*/metabolism
Macrophage Activation*
Animals ; Mice ; Choline/metabolism ; Cytokines/metabolism ; Macrophages ; Mice, Inbred C57BL ; Up-Regulation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
ICG-mediated fluorescence-assisted debridement to promote wound healing.
Autorzy:
Zhu G; Department of General Surgery (Hepatobiliary Surgery), The Affiliated Hospital of Southwest Medical University, Luzhou, China.; Nuclear Medicine and Molecular Imaging Key Laboratory of Sichuan Province, Luzhou, China.; Department of Hepatobiliary Pancreatic and Splenic Surgery, Luzhou People's Hospital, Luzhou, China.
Gao B; Department of General Surgery (Hepatobiliary Surgery), The Affiliated Hospital of Southwest Medical University, Luzhou, China.; Nuclear Medicine and Molecular Imaging Key Laboratory of Sichuan Province, Luzhou, China.; Academician (Expert) Workstation of Sichuan Province, Luzhou, China.
Fan J; Department of General Surgery (Hepatobiliary Surgery), The Affiliated Hospital of Southwest Medical University, Luzhou, China.; Nuclear Medicine and Molecular Imaging Key Laboratory of Sichuan Province, Luzhou, China.; Academician (Expert) Workstation of Sichuan Province, Luzhou, China.
Chen J; Department of General Surgery (Hepatobiliary Surgery), The Affiliated Hospital of Southwest Medical University, Luzhou, China.; Nuclear Medicine and Molecular Imaging Key Laboratory of Sichuan Province, Luzhou, China.; Academician (Expert) Workstation of Sichuan Province, Luzhou, China.
Su S; Department of General Surgery (Hepatobiliary Surgery), The Affiliated Hospital of Southwest Medical University, Luzhou, China.; Nuclear Medicine and Molecular Imaging Key Laboratory of Sichuan Province, Luzhou, China.; Academician (Expert) Workstation of Sichuan Province, Luzhou, China.
Yang X; Department of General Surgery (Hepatobiliary Surgery), The Affiliated Hospital of Southwest Medical University, Luzhou, China.; Nuclear Medicine and Molecular Imaging Key Laboratory of Sichuan Province, Luzhou, China.; Academician (Expert) Workstation of Sichuan Province, Luzhou, China.
Li B; Department of General Surgery (Hepatobiliary Surgery), The Affiliated Hospital of Southwest Medical University, Luzhou, China.; Nuclear Medicine and Molecular Imaging Key Laboratory of Sichuan Province, Luzhou, China.; Academician (Expert) Workstation of Sichuan Province, Luzhou, China.
Fang C; Department of General Surgery (Hepatobiliary Surgery), The Affiliated Hospital of Southwest Medical University, Luzhou, China.; Nuclear Medicine and Molecular Imaging Key Laboratory of Sichuan Province, Luzhou, China.; Academician (Expert) Workstation of Sichuan Province, Luzhou, China.
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Źródło:
PloS one [PLoS One] 2023 Sep 21; Vol. 18 (9), pp. e0291508. Date of Electronic Publication: 2023 Sep 21 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Interleukin-4*
Interferon-gamma*
Animals ; Rats ; Debridement ; Body Weight ; Control Groups ; Necrosis ; Wound Healing
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Interlukin-4 weakens resistance to stress injury and megakaryocytic differentiation of hematopoietic stem cells by inhibiting Psmd13 expression.
Autorzy:
Gao A; Department of Medical Oncology, Tianjin Medical University General Hospital, Tianjin, China.
Xu S; Medical School, Kunming University of Science and Technology, The First People's Hospital of Yunnan Province, Kunming, China.
Li Q; State Key Laboratory of Experimental Hematology, Tianjin, China.; Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China.; Center for Stem Cell Medicine, Chinese Academy of Medical Sciences, Tianjin, China.; Department of Stem Cell and Regenerative Medicine, Peking Union Medical College, Tianjin, China.
Zhu C; State Key Laboratory of Experimental Hematology, Tianjin, China.; Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China.; Center for Stem Cell Medicine, Chinese Academy of Medical Sciences, Tianjin, China.; Department of Stem Cell and Regenerative Medicine, Peking Union Medical College, Tianjin, China.
Wang F; State Key Laboratory of Experimental Hematology, Tianjin, China.; Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China.; Center for Stem Cell Medicine, Chinese Academy of Medical Sciences, Tianjin, China.; Department of Stem Cell and Regenerative Medicine, Peking Union Medical College, Tianjin, China.
Wang Y; Medical School, Kunming University of Science and Technology, The First People's Hospital of Yunnan Province, Kunming, China.
Hao S; State Key Laboratory of Experimental Hematology, Tianjin, China.; Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China.; Center for Stem Cell Medicine, Chinese Academy of Medical Sciences, Tianjin, China.; Department of Stem Cell and Regenerative Medicine, Peking Union Medical College, Tianjin, China.
Dong F; State Key Laboratory of Experimental Hematology, Tianjin, China.; Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China.; Center for Stem Cell Medicine, Chinese Academy of Medical Sciences, Tianjin, China.; Department of Stem Cell and Regenerative Medicine, Peking Union Medical College, Tianjin, China.
Cheng H; State Key Laboratory of Experimental Hematology, Tianjin, China.; Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China.; Center for Stem Cell Medicine, Chinese Academy of Medical Sciences, Tianjin, China.; Department of Stem Cell and Regenerative Medicine, Peking Union Medical College, Tianjin, China.
Cheng T; State Key Laboratory of Experimental Hematology, Tianjin, China.; Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China.; Center for Stem Cell Medicine, Chinese Academy of Medical Sciences, Tianjin, China.; Department of Stem Cell and Regenerative Medicine, Peking Union Medical College, Tianjin, China.
Gong Y; Department of Hematology, The First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Nanjing, China. .
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Źródło:
Scientific reports [Sci Rep] 2023 Aug 31; Vol. 13 (1), pp. 14253. Date of Electronic Publication: 2023 Aug 31.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Interleukin-4*/genetics
Hematopoietic Stem Cells*
Humans ; Megakaryocytes ; Down-Regulation ; Cell Differentiation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Human Macrophages Polarized by Interaction with Apoptotic Cells Produce Fibrosis-Associated Mediators and Enhance Pro-Fibrotic Activity of Dermal Fibroblasts In Vitro.
Autorzy:
Maksimova A; Research Institute of Fundamental and Clinical Immunology, Novosibirsk 630099, Russia.
Shevela E; Research Institute of Fundamental and Clinical Immunology, Novosibirsk 630099, Russia.
Sakhno L; Research Institute of Fundamental and Clinical Immunology, Novosibirsk 630099, Russia.
Tikhonova M; Research Institute of Fundamental and Clinical Immunology, Novosibirsk 630099, Russia.
Ostanin A; Research Institute of Fundamental and Clinical Immunology, Novosibirsk 630099, Russia.
Chernykh E; Research Institute of Fundamental and Clinical Immunology, Novosibirsk 630099, Russia.
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Źródło:
Cells [Cells] 2023 Jul 25; Vol. 12 (15). Date of Electronic Publication: 2023 Jul 25.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Fibroblasts*/metabolism
Interleukin-4*/pharmacology
Interleukin-4*/metabolism
Humans ; Macrophages/metabolism ; Fibrosis ; Collagen/metabolism ; Apoptosis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Quantitative Evaluation of Interleukin-4 by Immunowall Devices Made of Gelatin Methacryloyl Hydrogel.
Autorzy:
Banno Y; Department of Applied Chemistry, Graduate School of Engineering, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan.
Nomiyama T; Department of Applied Chemistry, Graduate School of Engineering, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan.
Okuno S; Department of Applied Chemistry, Graduate School of Engineering, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan.
Ide S; Department of Applied Chemistry, Graduate School of Engineering, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan.
Kaji N; Department of Applied Chemistry, Graduate School of Engineering, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Jun 08; Vol. 28 (12). Date of Electronic Publication: 2023 Jun 08.
Typ publikacji:
Journal Article
MeSH Terms:
Interleukin-4*
Microfluidic Analytical Techniques*
Hydrogels/chemistry ; Enzyme-Linked Immunosorbent Assay ; Immunoassay/methods ; Gelatin ; Lab-On-A-Chip Devices
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Upregulation of LAG3 modulates the immune imbalance of CD4+ T-cell subsets and exacerbates disease progression in patients with alveolar echinococcosis and a mouse model.
Autorzy:
Li D; State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, Clinical Medicine Institute, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.; Basic Medical College, Xinjiang Medical University, Urumqi, Xinjiang, China.
Ainiwaer A; State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, Clinical Medicine Institute, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.; Basic Medical College, Xinjiang Medical University, Urumqi, Xinjiang, China.
Zheng X; State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, Clinical Medicine Institute, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.; Basic Medical College, Xinjiang Medical University, Urumqi, Xinjiang, China.
Wang M; State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, Clinical Medicine Institute, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.; Basic Medical College, Xinjiang Medical University, Urumqi, Xinjiang, China.
Shi Y; State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, Clinical Medicine Institute, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.; Basic Medical College, Xinjiang Medical University, Urumqi, Xinjiang, China.
Rousu Z; State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, Clinical Medicine Institute, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.; Basic Medical College, Xinjiang Medical University, Urumqi, Xinjiang, China.
Hou X; State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, Clinical Medicine Institute, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.; Basic Medical College, Xinjiang Medical University, Urumqi, Xinjiang, China.
Kang X; State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, Clinical Medicine Institute, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.; Basic Medical College, Xinjiang Medical University, Urumqi, Xinjiang, China.
Maimaiti M; State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, Clinical Medicine Institute, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.; Basic Medical College, Xinjiang Medical University, Urumqi, Xinjiang, China.
Wang H; State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, Clinical Medicine Institute, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.; Basic Medical College, Xinjiang Medical University, Urumqi, Xinjiang, China.; Xinjiang Key Laboratory of Echinococcosis, Clinical Medicine Institute, The First Affiliated Hospital of Xinjiang Medical University, and WHO Collaborating Centre on Prevention and Case Management of Echinococcosis, Urumqi, Xinjiang, China.
Li J; Basic Medical College, Xinjiang Medical University, Urumqi, Xinjiang, China.
Zhang C; State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, Clinical Medicine Institute, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.; Basic Medical College, Xinjiang Medical University, Urumqi, Xinjiang, China.; Xinjiang Key Laboratory of Echinococcosis, Clinical Medicine Institute, The First Affiliated Hospital of Xinjiang Medical University, and WHO Collaborating Centre on Prevention and Case Management of Echinococcosis, Urumqi, Xinjiang, China.
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Źródło:
PLoS pathogens [PLoS Pathog] 2023 May 12; Vol. 19 (5), pp. e1011396. Date of Electronic Publication: 2023 May 12 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
CD4-Positive T-Lymphocytes*
Interleukin-4*
Mice ; Animals ; Up-Regulation ; Th1 Cells ; Disease Progression
SCR Disease Name:
Alveolar echinococcosis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Poly-L-Lactic Acid Fillers Improved Dermal Collagen Synthesis by Modulating M2 Macrophage Polarization in Aged Animal Skin.
Autorzy:
Oh S; Functional Cellular Networks Laboratory, Lee Gil Ya Cancer and Diabetes Institute, Gachon University, Incheon 21999, Republic of Korea.
Lee JH; Doctorbom Clinic, Seoul 06614, Republic of Korea.; Department of Anatomy & Cell Biology, Gachon University College of Medicine, Incheon 21936, Republic of Korea.
Kim HM; Department of Anatomy & Cell Biology, Gachon University College of Medicine, Incheon 21936, Republic of Korea.
Batsukh S; Functional Cellular Networks Laboratory, Lee Gil Ya Cancer and Diabetes Institute, Gachon University, Incheon 21999, Republic of Korea.; Department of Anatomy & Cell Biology, Gachon University College of Medicine, Incheon 21936, Republic of Korea.
Sung MJ; SACCI Bio Co., Seoul 1007, Republic of Korea.
Lim TH; SACCI Bio Co., Seoul 1007, Republic of Korea.
Lee MH; SACCI Bio Co., Seoul 1007, Republic of Korea.
Son KH; Department of Thoracic and Cardiovascular Surgery, Gachon University Gil Medical Center, Gachon University, Incheon 21565, Republic of Korea.
Byun K; Functional Cellular Networks Laboratory, Lee Gil Ya Cancer and Diabetes Institute, Gachon University, Incheon 21999, Republic of Korea.; Department of Anatomy & Cell Biology, Gachon University College of Medicine, Incheon 21936, Republic of Korea.; Department of Health Sciences and Technology, Gachon Advanced Institute for Health & Sciences and Technology (GAIHST), Gachon University, Incheon 21999, Republic of Korea.
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Źródło:
Cells [Cells] 2023 May 05; Vol. 12 (9). Date of Electronic Publication: 2023 May 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Interleukin-4*/metabolism
Elastin*/metabolism
Animals ; Hydrogen Peroxide/pharmacology ; Hydrogen Peroxide/metabolism ; Interleukin-13/metabolism ; Transforming Growth Factor beta/metabolism ; Collagen/metabolism ; Macrophages/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
IL-4 Signaling Promotes Myoblast Differentiation and Fusion by Enhancing the Expression of MyoD, Myogenin, and Myomerger.
Autorzy:
Kurosaka M; Department of Physiology, St. Marianna University School of Medicine, Kanagawa 216-8511, Japan.
Hung YL; Institute of Health and Sports & Medicine, Juntendo University, Chiba 270-1695, Japan.
Machida S; Institute of Health and Sports & Medicine, Juntendo University, Chiba 270-1695, Japan.; Graduate School of Health and Sports Science, Juntendo University, Chiba 270-1695, Japan.
Kohda K; Department of Physiology, St. Marianna University School of Medicine, Kanagawa 216-8511, Japan.
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Źródło:
Cells [Cells] 2023 Apr 29; Vol. 12 (9). Date of Electronic Publication: 2023 Apr 29.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Interleukin-4*/pharmacology
Interleukin-4*/metabolism
Myogenic Regulatory Factors*/metabolism
Cell Differentiation/genetics ; Myoblasts/metabolism ; Myogenin/genetics ; Myogenin/metabolism ; Animals ; Mice
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Interleukin-4 from curcumin-activated OECs emerges as a central modulator for increasing M2 polarization of microglia/macrophage in OEC anti-inflammatory activity for functional repair of spinal cord injury.
Autorzy:
Guo J; Department of Joint Surgery, Hong Hui Hospital, Xi'an Jiaotong University, Xi'an, 710054, China.
Tang X; Basic Medical School Academy, Basic Medical School Academy, Shaanxi University of Chinese Medicine, Xianyang, 712046, China.; Translational Medicine Center, Hong Hui Hospital, Xi'an Jiaotong University, Xi'an, 710054, China.
Deng P; Basic Medical School Academy, Basic Medical School Academy, Shaanxi University of Chinese Medicine, Xianyang, 712046, China.; Translational Medicine Center, Hong Hui Hospital, Xi'an Jiaotong University, Xi'an, 710054, China.
Hui H; Department of Spine Surgery, Hong Hui Hospital, Xi'an Jiaotong University, Xi'an, 710054, China.
Chen B; Translational Medicine Center, Hong Hui Hospital, Xi'an Jiaotong University, Xi'an, 710054, China.
An J; Translational Medicine Center, Hong Hui Hospital, Xi'an Jiaotong University, Xi'an, 710054, China.
Zhang G; Translational Medicine Center, Hong Hui Hospital, Xi'an Jiaotong University, Xi'an, 710054, China.
Shi K; Translational Medicine Center, Hong Hui Hospital, Xi'an Jiaotong University, Xi'an, 710054, China.
Wang J; Translational Medicine Center, Hong Hui Hospital, Xi'an Jiaotong University, Xi'an, 710054, China.
He Y; School of Basic Medical Sciences, Ningxia Medical University, Yinchuan, 750004, Ningxia, China.
Hao D; Department of Spine Surgery, Hong Hui Hospital, Xi'an Jiaotong University, Xi'an, 710054, China. .
Yang H; Translational Medicine Center, Hong Hui Hospital, Xi'an Jiaotong University, Xi'an, 710054, China. yanghao71_.
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Źródło:
Cell communication and signaling : CCS [Cell Commun Signal] 2024 Mar 06; Vol. 22 (1), pp. 162. Date of Electronic Publication: 2024 Mar 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Curcumin*/pharmacology
Spinal Cord Injuries*/therapy
Animals ; Rats ; Microglia ; Interleukin-4/pharmacology ; Macrophages ; Anti-Inflammatory Agents
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Timing of Interleukin-4 Stimulation of Macrophages Determines Their Anti-Microbial Activity during Infection with Salmonella enterica Serovar Typhimurium.
Autorzy:
Brigo N; Department of Internal Medicine II, Medical University of Innsbruck, Anichstrasse 35, 6020 Innsbruck, Austria.
Neumaier E; Department of Internal Medicine II, Medical University of Innsbruck, Anichstrasse 35, 6020 Innsbruck, Austria.
Pfeifhofer-Obermair C; Department of Internal Medicine II, Medical University of Innsbruck, Anichstrasse 35, 6020 Innsbruck, Austria.
Grubwieser P; Department of Internal Medicine II, Medical University of Innsbruck, Anichstrasse 35, 6020 Innsbruck, Austria.
Engl S; Department of Internal Medicine II, Medical University of Innsbruck, Anichstrasse 35, 6020 Innsbruck, Austria.
Berger S; Department of Internal Medicine II, Medical University of Innsbruck, Anichstrasse 35, 6020 Innsbruck, Austria.
Seifert M; Department of Internal Medicine II, Medical University of Innsbruck, Anichstrasse 35, 6020 Innsbruck, Austria.; Christian Doppler Laboratory for Iron Metabolism and Anemia Research, Medical University of Innsbruck, Anichstrasse 35, 6020 Innsbruck, Austria.
Reinstadler V; Institute of Legal Medicine and Core Facility Metabolomics, Medical University of Innsbruck, Muellerstrasse 44, 6020 Innsbruck, Austria.
Oberacher H; Institute of Legal Medicine and Core Facility Metabolomics, Medical University of Innsbruck, Muellerstrasse 44, 6020 Innsbruck, Austria.
Weiss G; Department of Internal Medicine II, Medical University of Innsbruck, Anichstrasse 35, 6020 Innsbruck, Austria.; Christian Doppler Laboratory for Iron Metabolism and Anemia Research, Medical University of Innsbruck, Anichstrasse 35, 6020 Innsbruck, Austria.
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Źródło:
Cells [Cells] 2023 Apr 14; Vol. 12 (8). Date of Electronic Publication: 2023 Apr 14.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Salmonella typhimurium*
Interleukin-4*/metabolism
Mice ; Animals ; Serogroup ; Mice, Inbred C57BL ; Macrophages/metabolism ; Interferon-gamma/metabolism ; Arginine/pharmacology ; Arginine/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Distinct Responses to IL4 in Macrophages Mediated by JNK.
Autorzy:
Arpa L; Biology of Macrophages Group, Department of Cellular Biology, Physiology and Immunology, Universitat de Barcelona, 08007 Barcelona, Spain.
Batlle C; Biology of Macrophages Group, Department of Cellular Biology, Physiology and Immunology, Universitat de Barcelona, 08007 Barcelona, Spain.
Jiang P; Biology of Macrophages Group, Department of Cellular Biology, Physiology and Immunology, Universitat de Barcelona, 08007 Barcelona, Spain.
Caelles C; Institute of Biomedicine, Universitat de Barcelona (IBUB), 08028 Barcelona, Spain.; Department of Biochemistry and Physiology, School of Pharmacy and Food Sciences, Universitat de Barcelona, 08028 Barcelona, Spain.
Lloberas J; Biology of Macrophages Group, Department of Cellular Biology, Physiology and Immunology, Universitat de Barcelona, 08007 Barcelona, Spain.
Celada A; Biology of Macrophages Group, Department of Cellular Biology, Physiology and Immunology, Universitat de Barcelona, 08007 Barcelona, Spain.
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Źródło:
Cells [Cells] 2023 Apr 11; Vol. 12 (8). Date of Electronic Publication: 2023 Apr 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Arginase*/metabolism
Interleukin-4*/pharmacology
Interleukin-4*/metabolism
Macrophages/metabolism ; Mitogen-Activated Protein Kinases/metabolism ; Phosphorylation ; Animals ; Mice
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Intranasal administration of interleukin-4 ameliorates depression-like behavior and biochemical alterations in mouse submitted to the chronic unpredictable mild stress: modulation of neuroinflammation and oxidative stress.
Autorzy:
Smaniotto TÂ; Technology Development Center, Division of Biotechnology, Neurobiotechnology Research Group, Federal University of Pelotas, Pelotas, RS, 96010900, Brazil.
Casaril AM; Technology Development Center, Division of Biotechnology, Neurobiotechnology Research Group, Federal University of Pelotas, Pelotas, RS, 96010900, Brazil.
de Andrade Lourenço D; Technology Development Center, Division of Biotechnology, Neurobiotechnology Research Group, Federal University of Pelotas, Pelotas, RS, 96010900, Brazil.
Sousa FS; Technology Development Center, Division of Biotechnology, Cancer Biotechnology Laboratory, Federal University of Pelotas, Pelotas, RS, 96010900, Brazil.
Seixas FK; Technology Development Center, Division of Biotechnology, Cancer Biotechnology Laboratory, Federal University of Pelotas, Pelotas, RS, 96010900, Brazil.
Collares T; Technology Development Center, Division of Biotechnology, Cancer Biotechnology Laboratory, Federal University of Pelotas, Pelotas, RS, 96010900, Brazil.
Woloski R; Technology Development Center, Division of Biotechnology, Bioinformatics and Proteomics Laboratory, Federal University of Pelotas, Pelotas, RS, 96010900, Brazil.
da Silva Pinto L; Technology Development Center, Division of Biotechnology, Bioinformatics and Proteomics Laboratory, Federal University of Pelotas, Pelotas, RS, 96010900, Brazil.
Alves D; Center of Chemical, Pharmaceutical and Food Sciences, Laboratory of Clean Organic Synthesis, Federal University of Pelotas, Pelotas, RS, 96010900, Brazil.
Savegnago L; Technology Development Center, Division of Biotechnology, Neurobiotechnology Research Group, Federal University of Pelotas, Pelotas, RS, 96010900, Brazil. .; Center of Chemical, Pharmaceutical and Food Sciences, Laboratory of Clean Organic Synthesis, Federal University of Pelotas, Pelotas, RS, 96010900, Brazil. .
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Źródło:
Psychopharmacology [Psychopharmacology (Berl)] 2023 Apr; Vol. 240 (4), pp. 935-950. Date of Electronic Publication: 2023 Mar 01.
Typ publikacji:
Journal Article
MeSH Terms:
Depression*/psychology
Interleukin-4*
Mice ; Animals ; Neuroinflammatory Diseases ; Administration, Intranasal ; Oxidative Stress ; Stress, Psychological/psychology ; Disease Models, Animal ; Brain-Derived Neurotrophic Factor/metabolism ; Hippocampus
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 17148

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