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Wyszukujesz frazę ""Interleukin-6"" wg kryterium: Wszystkie pola


Tytuł :
The bio-mission of interleukin-6 in the pathogenesis of COVID-19: A brief look at potential therapeutic tactics.
Autorzy :
Abbasifard M; Molecular Medicine Research Center, Research Institute of Basic Medical Sciences, Rafsanjan University of Medical Sciences, Rafsanjan, Iran; Department of Internal Medicine, Ali-Ibn-Abi-talib Hospital, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Khorramdelazad H; Molecular Medicine Research Center, Research Institute of Basic Medical Sciences, Rafsanjan University of Medical Sciences, Rafsanjan, Iran; Department of Immunology, School of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran; Department of Immunology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 Sep 15; Vol. 257, pp. 118097. Date of Electronic Publication: 2020 Jul 15.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Betacoronavirus/*immunology
Coronavirus Infections/*immunology
Interleukin-6/*immunology
Pneumonia, Viral/*immunology
Betacoronavirus/metabolism ; Coronavirus Infections/metabolism ; Cytokines/immunology ; Humans ; Inflammation/immunology ; Interleukin-6/metabolism ; Interleukin-6/pharmacology ; Middle East Respiratory Syndrome Coronavirus/immunology ; Pandemics ; Pneumonia, Viral/metabolism ; SARS Virus/immunology
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Taste and Smell Disorders in COVID-19 Patients: Role of Interleukin-6.
Autorzy :
Cazzolla AP; Department of Clinical and Experimental Medicine, Università degli Studi di Foggia, Foggia 71122, Italy.
Lovero R; AOU Policlinico Consorziale di Bari - Ospedale Giovanni XXIII, Clinical Pathology Unit, Bari 70124, Italy.
Lo Muzio L; Department of Clinical and Experimental Medicine, Università degli Studi di Foggia, Foggia 71122, Italy.
Testa NF; Department of Clinical and Experimental Medicine, Università degli Studi di Foggia, Foggia 71122, Italy.
Schirinzi A; AOU Policlinico Consorziale di Bari - Ospedale Giovanni XXIII, Clinical Pathology Unit, Bari 70124, Italy.
Palmieri G; Private practice, Bari 70124, Italy.
Pozzessere P; AOU Policlinico Consorziale di Bari - Ospedale Giovanni XXIII, Emergency Medicine and Surgery Unit, Bari 70124, Italy.
Procacci V; AOU Policlinico Consorziale di Bari - Ospedale Giovanni XXIII, Emergency Medicine and Surgery Unit, Bari 70124, Italy.
Di Comite M; Department of Basic Medical Sciences, Neurosciences and Sensory Organs, Human Anatomy Section, Università degli Studi di Bari, Bari 70124, Italy.
Ciavarella D; Department of Clinical and Experimental Medicine, Università degli Studi di Foggia, Foggia 71122, Italy.
Pepe M; AOU Policlinico Consorziale di Bari - Ospedale Giovanni XXIII, Clinical Pathology Unit, Bari 70124, Italy.
De Ruvo C; Maugeri Clinical Research Institutes IRCCS of Bari, Bari 70124, Italy.
Crincoli V; Department of Basic Medical Sciences, Neurosciences and Sensory Organs, Human Anatomy Section, Università degli Studi di Bari, Bari 70124, Italy.
Di Serio F; AOU Policlinico Consorziale di Bari - Ospedale Giovanni XXIII, Clinical Pathology Unit, Bari 70124, Italy.
Santacroce L; Ionian Department (DJSGEM), Microbiology and Virology Lab, Università degli Studi di Bari, Bari 70124, Italy.
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Źródło :
ACS chemical neuroscience [ACS Chem Neurosci] 2020 Sep 02; Vol. 11 (17), pp. 2774-2781. Date of Electronic Publication: 2020 Aug 19.
Typ publikacji :
Journal Article; Observational Study
MeSH Terms :
Betacoronavirus*
Coronavirus Infections/*blood
Interleukin-6/*blood
Olfaction Disorders/*blood
Pneumonia, Viral/*blood
Taste Disorders/*blood
Aged ; Aged, 80 and over ; Biomarkers/blood ; Coronavirus Infections/complications ; Coronavirus Infections/diagnosis ; Female ; Health Surveys/methods ; Humans ; Interleukin-6/physiology ; Male ; Middle Aged ; Olfaction Disorders/diagnosis ; Olfaction Disorders/etiology ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/diagnosis ; Taste/physiology ; Taste Disorders/diagnosis ; Taste Disorders/etiology
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Effect of NMO-IgG on the interleukin-6 cascade in astrocytes via activation of the JAK/STAT3 signaling pathway.
Autorzy :
Du L; Department of Neurology, Beijing Tiantan Hospital; China National Clinical Research Center for Neurological Diseases; Advanced Innovation Center for Human Brain Protection, Beijing Institute of Brain Disorders, Capital Medical University, No.119 South 4th Ring West Road, Fengtai District, Beijing 100070, China.
Chang H; Department of Neurology, Beijing Tiantan Hospital; China National Clinical Research Center for Neurological Diseases; Advanced Innovation Center for Human Brain Protection, Beijing Institute of Brain Disorders, Capital Medical University, No.119 South 4th Ring West Road, Fengtai District, Beijing 100070, China.
Xu W; Department of Neurology, Beijing Tiantan Hospital; China National Clinical Research Center for Neurological Diseases; Advanced Innovation Center for Human Brain Protection, Beijing Institute of Brain Disorders, Capital Medical University, No.119 South 4th Ring West Road, Fengtai District, Beijing 100070, China.
Wei Y; Department of Neurology, Beijing Tiantan Hospital; China National Clinical Research Center for Neurological Diseases; Advanced Innovation Center for Human Brain Protection, Beijing Institute of Brain Disorders, Capital Medical University, No.119 South 4th Ring West Road, Fengtai District, Beijing 100070, China.
Wang Y; Department of Neurology, Beijing Tiantan Hospital; China National Clinical Research Center for Neurological Diseases; Advanced Innovation Center for Human Brain Protection, Beijing Institute of Brain Disorders, Capital Medical University, No.119 South 4th Ring West Road, Fengtai District, Beijing 100070, China.
Yin L; Department of Neurology, Beijing Tiantan Hospital; China National Clinical Research Center for Neurological Diseases; Advanced Innovation Center for Human Brain Protection, Beijing Institute of Brain Disorders, Capital Medical University, No.119 South 4th Ring West Road, Fengtai District, Beijing 100070, China. Electronic address: .
Zhang X; Department of Neurology, Beijing Tiantan Hospital; China National Clinical Research Center for Neurological Diseases; Advanced Innovation Center for Human Brain Protection, Beijing Institute of Brain Disorders, Capital Medical University, No.119 South 4th Ring West Road, Fengtai District, Beijing 100070, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 Oct 01; Vol. 258, pp. 118217. Date of Electronic Publication: 2020 Aug 06.
Typ publikacji :
Journal Article
MeSH Terms :
Astrocytes/*metabolism
Immunoglobulin G/*blood
Interleukin-6/*metabolism
Janus Kinases/*metabolism
Neuromyelitis Optica/*blood
STAT3 Transcription Factor/*metabolism
Adult ; Aged ; Animals ; Astrocytes/drug effects ; Autoantibodies/blood ; Autoantibodies/pharmacology ; Cells, Cultured ; Female ; Humans ; Immunoglobulin G/pharmacology ; Interleukin-6/agonists ; Male ; Middle Aged ; Rats ; Rats, Wistar ; STAT3 Transcription Factor/agonists ; Signal Transduction/drug effects ; Signal Transduction/physiology ; Young Adult
Czasopismo naukowe
Tytuł :
Interleukin-6: Molecule in the Intersection of Cancer, Ageing and COVID-19.
Autorzy :
Brábek J; Department of Cell Biology, Faculty of Science, Charles University, 120 00 Prague 2, Czech Republic.; BIOCEV, Faculty of Science, Charles University, 252 50 Vestec, Czech Republic.; Centre for Tumour Ecology, First Faculty of Medicine, Charles University, 120 00 Prague 2, Czech Republic.
Jakubek M; Centre for Tumour Ecology, First Faculty of Medicine, Charles University, 120 00 Prague 2, Czech Republic.; Department of Paediatrics and Adolescent Medicine, First Faculty of Medicine, Charles University and General University Hospital, 120 00 Prague, Czech Republic.; BIOCEV, First Faculty of Medicine, Charles University, 252 50 Vestec, Czech Republic.; Department of Analytical Chemistry, University of Chemistry and Technology Prague, 166 28 Praha 6, Czech Republic.
Vellieux F; Centre for Tumour Ecology, First Faculty of Medicine, Charles University, 120 00 Prague 2, Czech Republic.; BIOCEV, First Faculty of Medicine, Charles University, 252 50 Vestec, Czech Republic.
Novotný J; Centre for Tumour Ecology, First Faculty of Medicine, Charles University, 120 00 Prague 2, Czech Republic.; Laboratory of Genomics and Bioinformatics, Institute of Molecular Genetics, Czech Academy of Sciences, 140 00 Prague 4, Czech Republic.
Kolář M; Centre for Tumour Ecology, First Faculty of Medicine, Charles University, 120 00 Prague 2, Czech Republic.; Laboratory of Genomics and Bioinformatics, Institute of Molecular Genetics, Czech Academy of Sciences, 140 00 Prague 4, Czech Republic.
Lacina L; Centre for Tumour Ecology, First Faculty of Medicine, Charles University, 120 00 Prague 2, Czech Republic.; BIOCEV, First Faculty of Medicine, Charles University, 252 50 Vestec, Czech Republic.; Institute of Anatomy, Fist Faculty of Medicine, Charles University, 120 00 Prague 2, Czech Republic.; Department of Dermatovenereology, First Faculty of Medicine, Charles University and General University Hospital, 120 00 Prague 2, Czech Republic.
Szabo P; Institute of Anatomy, Fist Faculty of Medicine, Charles University, 120 00 Prague 2, Czech Republic.
Strnadová K; Centre for Tumour Ecology, First Faculty of Medicine, Charles University, 120 00 Prague 2, Czech Republic.; BIOCEV, First Faculty of Medicine, Charles University, 252 50 Vestec, Czech Republic.; Institute of Anatomy, Fist Faculty of Medicine, Charles University, 120 00 Prague 2, Czech Republic.
Rösel D; Department of Cell Biology, Faculty of Science, Charles University, 120 00 Prague 2, Czech Republic.; BIOCEV, Faculty of Science, Charles University, 252 50 Vestec, Czech Republic.; Centre for Tumour Ecology, First Faculty of Medicine, Charles University, 120 00 Prague 2, Czech Republic.
Dvořánková B; Centre for Tumour Ecology, First Faculty of Medicine, Charles University, 120 00 Prague 2, Czech Republic.; BIOCEV, First Faculty of Medicine, Charles University, 252 50 Vestec, Czech Republic.; Institute of Anatomy, Fist Faculty of Medicine, Charles University, 120 00 Prague 2, Czech Republic.
Smetana K Jr; Centre for Tumour Ecology, First Faculty of Medicine, Charles University, 120 00 Prague 2, Czech Republic.; BIOCEV, First Faculty of Medicine, Charles University, 252 50 Vestec, Czech Republic.; Institute of Anatomy, Fist Faculty of Medicine, Charles University, 120 00 Prague 2, Czech Republic.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Oct 26; Vol. 21 (21). Date of Electronic Publication: 2020 Oct 26.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Aging/*metabolism
Coronavirus Infections/*metabolism
Interleukin-6/*metabolism
Neoplasms/*metabolism
Pneumonia, Viral/*metabolism
Aging/pathology ; Animals ; Coronavirus Infections/pathology ; Humans ; Interleukin-6/genetics ; Neoplasms/pathology ; Pandemics ; Pneumonia, Viral/pathology ; Signal Transduction
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Interleukin-6 trans-signaling is a candidate mechanism to drive progression of human DCCs during clinical latency.
Autorzy :
Werner-Klein M; Experimental Medicine and Therapy Research, University of Regensburg, Regensburg, Germany. .
Grujovic A; Experimental Medicine and Therapy Research, University of Regensburg, Regensburg, Germany.; Telexos GmbH, Weilheim, Germany.
Irlbeck C; Experimental Medicine and Therapy Research, University of Regensburg, Regensburg, Germany.; Division of Personalized Tumour Therapy, Fraunhofer Institute for Toxicology and Experimental Medicine, 93053, Regensburg, Germany.
Obradović M; Experimental Medicine and Therapy Research, University of Regensburg, Regensburg, Germany.; Wellmera AG, Basel, Switzerland.
Hoffmann M; Division of Personalized Tumour Therapy, Fraunhofer Institute for Toxicology and Experimental Medicine, 93053, Regensburg, Germany.
Koerkel-Qu H; Experimental Medicine and Therapy Research, University of Regensburg, Regensburg, Germany.
Lu X; Division of Personalized Tumour Therapy, Fraunhofer Institute for Toxicology and Experimental Medicine, 93053, Regensburg, Germany.
Treitschke S; Division of Personalized Tumour Therapy, Fraunhofer Institute for Toxicology and Experimental Medicine, 93053, Regensburg, Germany.
Köstler C; Division of Personalized Tumour Therapy, Fraunhofer Institute for Toxicology and Experimental Medicine, 93053, Regensburg, Germany.
Botteron C; Division of Personalized Tumour Therapy, Fraunhofer Institute for Toxicology and Experimental Medicine, 93053, Regensburg, Germany.
Weidele K; Division of Personalized Tumour Therapy, Fraunhofer Institute for Toxicology and Experimental Medicine, 93053, Regensburg, Germany.
Werno C; Division of Personalized Tumour Therapy, Fraunhofer Institute for Toxicology and Experimental Medicine, 93053, Regensburg, Germany.
Polzer B; Division of Personalized Tumour Therapy, Fraunhofer Institute for Toxicology and Experimental Medicine, 93053, Regensburg, Germany.
Kirsch S; Division of Personalized Tumour Therapy, Fraunhofer Institute for Toxicology and Experimental Medicine, 93053, Regensburg, Germany.
Gužvić M; Experimental Medicine and Therapy Research, University of Regensburg, Regensburg, Germany.
Warfsmann J; Division of Personalized Tumour Therapy, Fraunhofer Institute for Toxicology and Experimental Medicine, 93053, Regensburg, Germany.
Honarnejad K; Division of Personalized Tumour Therapy, Fraunhofer Institute for Toxicology and Experimental Medicine, 93053, Regensburg, Germany.
Czyz Z; Experimental Medicine and Therapy Research, University of Regensburg, Regensburg, Germany.
Feliciello G; Division of Personalized Tumour Therapy, Fraunhofer Institute for Toxicology and Experimental Medicine, 93053, Regensburg, Germany.
Blochberger I; Experimental Medicine and Therapy Research, University of Regensburg, Regensburg, Germany.
Grunewald S; Experimental Medicine and Therapy Research, University of Regensburg, Regensburg, Germany.
Schneider E; Experimental Medicine and Therapy Research, University of Regensburg, Regensburg, Germany.
Haunschild G; Experimental Medicine and Therapy Research, University of Regensburg, Regensburg, Germany.
Patwary N; Experimental Medicine and Therapy Research, University of Regensburg, Regensburg, Germany.
Guetter S; Experimental Medicine and Therapy Research, University of Regensburg, Regensburg, Germany.
Huber S; Experimental Medicine and Therapy Research, University of Regensburg, Regensburg, Germany.
Rack B; Department OB&GYN and CCCLMU, Breast Center, LMU University Hospital, 80337, Munich, Germany.; Department of Gynecology, Ulm University Hospital, Ulm, Germany.
Harbeck N; Department OB&GYN and CCCLMU, Breast Center, LMU University Hospital, 80337, Munich, Germany.
Buchholz S; Clinic of Gynecology and Obstetrics, University Medical Center Regensburg, 93053, Regensburg, Germany.
Rümmele P; Department of Pathology, University of Regensburg, 93053, Regensburg, Germany.; Institute of Pathology, University Hospital, Friedrich-Alexander-University Erlangen-Nürnberg, 91054, Erlangen, Germany.
Heine N; University Center of Plastic-, Aesthetic, Hand- and Reconstructive Surgery, University of Regensburg, Regensburg, Germany.
Rose-John S; Institute of Biochemistry, Christian-Albrechts-Universität Kiel, Kiel, Germany.
Klein CA; Experimental Medicine and Therapy Research, University of Regensburg, Regensburg, Germany. .; Division of Personalized Tumour Therapy, Fraunhofer Institute for Toxicology and Experimental Medicine, 93053, Regensburg, Germany. .
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Źródło :
Nature communications [Nat Commun] 2020 Oct 05; Vol. 11 (1), pp. 4977. Date of Electronic Publication: 2020 Oct 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Signal Transduction*
Interleukin-6/*metabolism
Neoplastic Stem Cells/*metabolism
Neoplastic Stem Cells/*pathology
Bone Marrow/pathology ; Breast/cytology ; Breast Neoplasms/pathology ; Class I Phosphatidylinositol 3-Kinases/genetics ; Class I Phosphatidylinositol 3-Kinases/metabolism ; Cytokine Receptor gp130/metabolism ; Epithelial Cells/metabolism ; Epithelial Cells/pathology ; Female ; Humans ; Interleukin-6/genetics ; Mutation ; Neoplasm Metastasis/genetics ; Receptors, Interleukin-6/deficiency ; Receptors, Interleukin-6/metabolism ; Stromal Cells/metabolism ; Tumor Microenvironment
Czasopismo naukowe
Tytuł :
Duplex Shiny app quantification of the sepsis biomarkers C-reactive protein and interleukin-6 in a fast quantum dot labeled lateral flow assay.
Autorzy :
Ruppert C; Medical and Life Sciences Faculty, Furtwangen University, Jakob-Kienzle Str. 17, 78054, Villingen-Schwenningen, Germany.; Institute of Precision Medicine, Furtwangen University, Jakob-Kienzle Str. 17, 78054, Villingen-Schwenningen, Germany.; Department of Pharmaceutical Chemistry, Pharmaceutical Institute, University of Tuebingen, Auf der Morgenstelle 8, 72076, Tübingen, Germany.
Kaiser L; Medical and Life Sciences Faculty, Furtwangen University, Jakob-Kienzle Str. 17, 78054, Villingen-Schwenningen, Germany.; Institute of Precision Medicine, Furtwangen University, Jakob-Kienzle Str. 17, 78054, Villingen-Schwenningen, Germany.; Institute of Pharmaceutical Sciences, University of Freiburg, Albertstraße 25, 79104, Freiburg, Germany.
Jacob LJ; Medical and Life Sciences Faculty, Furtwangen University, Jakob-Kienzle Str. 17, 78054, Villingen-Schwenningen, Germany.; Institute of Precision Medicine, Furtwangen University, Jakob-Kienzle Str. 17, 78054, Villingen-Schwenningen, Germany.
Laufer S; Department of Pharmaceutical Chemistry, Pharmaceutical Institute, University of Tuebingen, Auf der Morgenstelle 8, 72076, Tübingen, Germany.
Kohl M; Medical and Life Sciences Faculty, Furtwangen University, Jakob-Kienzle Str. 17, 78054, Villingen-Schwenningen, Germany. .; Institute of Precision Medicine, Furtwangen University, Jakob-Kienzle Str. 17, 78054, Villingen-Schwenningen, Germany. .
Deigner HP; Medical and Life Sciences Faculty, Furtwangen University, Jakob-Kienzle Str. 17, 78054, Villingen-Schwenningen, Germany. .; Institute of Precision Medicine, Furtwangen University, Jakob-Kienzle Str. 17, 78054, Villingen-Schwenningen, Germany. .; EXIM Department, Fraunhofer Institute IZI, Leipzig, Schillingallee 68, 18057, Rostock, Germany. .; Faculty of Science, Tuebingen University, Auf der Morgenstelle 8, 72076, Tübingen, Germany. .
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Źródło :
Journal of nanobiotechnology [J Nanobiotechnology] 2020 Sep 10; Vol. 18 (1), pp. 130. Date of Electronic Publication: 2020 Sep 10.
Typ publikacji :
Journal Article
MeSH Terms :
Biomarkers/*analysis
C-Reactive Protein/*analysis
Immunoassay/*methods
Interleukin-6/*analysis
Quantum Dots/*chemistry
Sepsis/*diagnosis
Antibodies/immunology ; Betacoronavirus/isolation & purification ; C-Reactive Protein/immunology ; Coronavirus Infections/diagnosis ; Coronavirus Infections/virology ; Humans ; Interleukin-6/immunology ; Limit of Detection ; Pandemics ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/virology ; Point-of-Care Systems ; Sepsis/metabolism ; Software ; Ultraviolet Rays
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Interleukin-6 blockade with sarilumab in severe COVID-19 pneumonia with systemic hyperinflammation: an open-label cohort study.
Autorzy :
Della-Torre E; Unit of Immunology, Rheumatology, Allergy, and Rare Diseases, San Raffaele Hospital, Milano, Lombardia, Italy .; Università Vita-Salute San Raffaele, Milan, Italy.
Campochiaro C; Unit of Immunology, Rheumatology, Allergy, and Rare Diseases, San Raffaele Hospital, Milano, Lombardia, Italy.; Università Vita-Salute San Raffaele, Milan, Italy.
Cavalli G; Unit of Immunology, Rheumatology, Allergy, and Rare Diseases, San Raffaele Hospital, Milano, Lombardia, Italy.; Università Vita-Salute San Raffaele, Milan, Italy.
De Luca G; Unit of Immunology, Rheumatology, Allergy, and Rare Diseases, San Raffaele Hospital, Milano, Lombardia, Italy.; Università Vita-Salute San Raffaele, Milan, Italy.
Napolitano A; Università Vita-Salute San Raffaele, Milan, Italy.; Clinical and Experimental Radiology Unit, Experimental Imaging Center, San Raffaele Hospital, Milan, Italy.
La Marca S; Università Vita-Salute San Raffaele, Milan, Italy.; Clinical and Experimental Radiology Unit, Experimental Imaging Center, San Raffaele Hospital, Milan, Italy.
Boffini N; Unit of Immunology, Rheumatology, Allergy, and Rare Diseases, San Raffaele Hospital, Milano, Lombardia, Italy.
Da Prat V; General Medicine and Advanced Care Unit, San Raffaele Hospital, Milan, Italy.
Di Terlizzi G; General Medicine and Advanced Care Unit, San Raffaele Hospital, Milan, Italy.
Lanzillotta M; Unit of Immunology, Rheumatology, Allergy, and Rare Diseases, San Raffaele Hospital, Milano, Lombardia, Italy.; Università Vita-Salute San Raffaele, Milan, Italy.
Rovere Querini P; Università Vita-Salute San Raffaele, Milan, Italy.; Internal Medicine, Diabetes & Endocrinology Unit, San Raffaele Hospital, Milan, Italy.
Ruggeri A; Hematology and Bone Marrow Transplant Unit, San Raffaele Hospital, Milan, Italy.
Landoni G; Università Vita-Salute San Raffaele, Milan, Italy.; Department of Anesthesia and Intensive Care, San Raffaele Hospital, Milan, Italy.
Tresoldi M; General Medicine and Advanced Care Unit, San Raffaele Hospital, Milan, Italy.
Ciceri F; Università Vita-Salute San Raffaele, Milan, Italy.; Hematology and Bone Marrow Transplant Unit, San Raffaele Hospital, Milan, Italy.
Zangrillo A; Università Vita-Salute San Raffaele, Milan, Italy.; Department of Anesthesia and Intensive Care, San Raffaele Hospital, Milan, Italy.
De Cobelli F; Università Vita-Salute San Raffaele, Milan, Italy.; Clinical and Experimental Radiology Unit, Experimental Imaging Center, San Raffaele Hospital, Milan, Italy.
Dagna L; Unit of Immunology, Rheumatology, Allergy, and Rare Diseases, San Raffaele Hospital, Milano, Lombardia, Italy .; Università Vita-Salute San Raffaele, Milan, Italy.
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Corporate Authors :
SARI-RAF Study Group
SARI-RAF Study Group members
Źródło :
Annals of the rheumatic diseases [Ann Rheum Dis] 2020 Oct; Vol. 79 (10), pp. 1277-1285. Date of Electronic Publication: 2020 Jul 03.
Typ publikacji :
Journal Article; Observational Study
MeSH Terms :
Antibodies, Monoclonal, Humanized/*therapeutic use
C-Reactive Protein/*immunology
Coronavirus Infections/*drug therapy
Inflammation/*immunology
Interleukin-6/*immunology
Pneumonia, Viral/*drug therapy
Administration, Intravenous ; Anti-Bacterial Agents/therapeutic use ; Antiviral Agents/therapeutic use ; Azithromycin/therapeutic use ; Bacteremia/epidemiology ; Betacoronavirus ; Cohort Studies ; Coinfection/epidemiology ; Coronavirus Infections/diagnostic imaging ; Coronavirus Infections/immunology ; Coronavirus Infections/mortality ; Drug Combinations ; Enzyme Inhibitors/therapeutic use ; Female ; Humans ; Hydroxychloroquine/therapeutic use ; Italy ; Lopinavir/therapeutic use ; Lung/diagnostic imaging ; Male ; Middle Aged ; Noninvasive Ventilation ; Oxygen Inhalation Therapy ; Pandemics ; Pneumonia, Viral/diagnostic imaging ; Pneumonia, Viral/immunology ; Pneumonia, Viral/mortality ; Proportional Hazards Models ; Receptors, Interleukin-6/antagonists & inhibitors ; Ritonavir/therapeutic use ; Severity of Illness Index ; Time Factors ; Tomography, X-Ray Computed ; Treatment Outcome
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Changes in the cerebrospinal fluid lipid profile following subarachnoid hemorrhage in a closed cranium model: Correlations to cerebral vasospasm, neuronal cell death and Interleukin-6 synthesis. A pilot study.
Autorzy :
Croci D; Cerebrovascular Research Group, Department of BioMedical Research, University of Bern, Switzerland; Department of Neurosurgery, Neurocenter of Southern Switzerland, Regional Hospital Lugano, Switzerland. Electronic address: .
Nevzati E; Department of Neurosurgery, Kantonsspital Aarau, Aarau, Switzerland; Cerebrovascular Research Group, Department of BioMedical Research, University of Bern, Switzerland; Department of Neurosurgery, Kantonsspital Luzern, Lucerne, Switzerland. Electronic address: .
Muroi C; Department of Neurosurgery, Kantonsspital Aarau, Aarau, Switzerland.
Schöpf S; Department of Neurosurgery, Kantonsspital Aarau, Aarau, Switzerland. Electronic address: .
Hornemann T; Institute of Clinical Chemistry, University and University Hospital Zurich, Switzerland. Electronic address: .
Widmer HR; Department of Neurosurgery, Bern University Hospital, Inselspital Bern, Switzerland. Electronic address: .
Danura H; Department of Neurosurgery, Kantonsspital Aarau, Aarau, Switzerland; Cerebrovascular Research Group, Department of BioMedical Research, University of Bern, Switzerland. Electronic address: .
Fandino J; Department of Neurosurgery, Kantonsspital Aarau, Aarau, Switzerland; Cerebrovascular Research Group, Department of BioMedical Research, University of Bern, Switzerland. Electronic address: .
Marbacher S; Department of Neurosurgery, Kantonsspital Aarau, Aarau, Switzerland; Cerebrovascular Research Group, Department of BioMedical Research, University of Bern, Switzerland. Electronic address: .
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Źródło :
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association [J Stroke Cerebrovasc Dis] 2020 Sep; Vol. 29 (9), pp. 105054. Date of Electronic Publication: 2020 Jun 23.
Typ publikacji :
Journal Article
MeSH Terms :
Vasoconstriction*
Basilar Artery/*physiopathology
Interleukin-6/*cerebrospinal fluid
Lipids/*cerebrospinal fluid
Neurons/*metabolism
Subarachnoid Hemorrhage/*cerebrospinal fluid
Vasospasm, Intracranial/*cerebrospinal fluid
Animals ; Apoptosis ; Basilar Artery/diagnostic imaging ; Biomarkers/cerebrospinal fluid ; Disease Models, Animal ; Interleukin-6/biosynthesis ; Intracranial Pressure ; Neurons/pathology ; Phosphatidylcholines/cerebrospinal fluid ; Phosphatidylethanolamines/cerebrospinal fluid ; Pilot Projects ; Rabbits ; Subarachnoid Hemorrhage/diagnostic imaging ; Subarachnoid Hemorrhage/pathology ; Subarachnoid Hemorrhage/physiopathology ; Vasospasm, Intracranial/diagnostic imaging ; Vasospasm, Intracranial/pathology ; Vasospasm, Intracranial/physiopathology
Czasopismo naukowe
Tytuł :
Sepsis-associated severe interleukin-6 storm in critical coronavirus disease 2019.
Autorzy :
Huang L; Biotherapy Center, The First Affiliated Hospital, Zhengzhou University, No. 1 Jianshe East Road, 450052, Zhengzhou, Henan, China. .
Zhao X; Biotherapy Center, The First Affiliated Hospital, Zhengzhou University, No. 1 Jianshe East Road, 450052, Zhengzhou, Henan, China.
Qi Y; Department of Thoracic Surgery, The First Affiliated Hospital, Zhengzhou University, No. 1 Jianshe East Road, 450052, Zhengzhou, Henan, China.
Li H; Biotherapy Center, The First Affiliated Hospital, Zhengzhou University, No. 1 Jianshe East Road, 450052, Zhengzhou, Henan, China.
Ye G; Department of Thoracic Surgery, The First Affiliated Hospital, Zhengzhou University, No. 1 Jianshe East Road, 450052, Zhengzhou, Henan, China.
Liu Y; Department of Thoracic Surgery, The First Affiliated Hospital, Zhengzhou University, No. 1 Jianshe East Road, 450052, Zhengzhou, Henan, China.
Zhang Y; Biotherapy Center, The First Affiliated Hospital, Zhengzhou University, No. 1 Jianshe East Road, 450052, Zhengzhou, Henan, China. .
Gou J; Department of Clinical Laboratory, The First Affiliated Hospital, Zhengzhou University, No. 1 Jianshe East Road, 450052, Zhengzhou, Henan, China. .
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Źródło :
Cellular & molecular immunology [Cell Mol Immunol] 2020 Oct; Vol. 17 (10), pp. 1092-1094. Date of Electronic Publication: 2020 Sep 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Betacoronavirus/*pathogenicity
Coronavirus Infections/*complications
Cytokine Release Syndrome/*complications
Interleukin-6/*immunology
Lymphopenia/*complications
Pneumonia, Viral/*complications
Sepsis/*complications
Acute Disease ; Betacoronavirus/immunology ; Biomarkers/blood ; Coronavirus Infections/immunology ; Coronavirus Infections/mortality ; Coronavirus Infections/virology ; Critical Illness ; Cytokine Release Syndrome/immunology ; Cytokine Release Syndrome/mortality ; Cytokine Release Syndrome/virology ; Humans ; Interferon-gamma/blood ; Interferon-gamma/immunology ; Interleukin-10/blood ; Interleukin-10/immunology ; Interleukin-2/blood ; Interleukin-2/immunology ; Interleukin-4/blood ; Interleukin-4/immunology ; Interleukin-6/blood ; Lymphopenia/immunology ; Lymphopenia/mortality ; Lymphopenia/virology ; Pandemics ; Pneumonia, Viral/immunology ; Pneumonia, Viral/mortality ; Pneumonia, Viral/virology ; Procalcitonin/blood ; Procalcitonin/immunology ; Sepsis/immunology ; Sepsis/mortality ; Sepsis/virology ; Survival Analysis ; Tumor Necrosis Factor-alpha/blood ; Tumor Necrosis Factor-alpha/immunology
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Impact of interleukin-6 blockade with tocilizumab on SARS-CoV-2 viral kinetics and antibody responses in patients with COVID-19: A prospective cohort study.
Autorzy :
Masiá M; Hospital General Universitario de Elche and Universidad Miguel Hernández, Camí de la Almazara 11, Elche, Alicante 03203, Spain. Electronic address: .
Fernández-González M; Hospital General Universitario de Elche, Camí de la Almazara 11, Elche, Alicante 03203, Spain.
Padilla S; Hospital General Universitario de Elche, Camí de la Almazara 11, Elche, Alicante 03203, Spain.
Ortega P; Hospital General Universitario de Elche, Camí de la Almazara 11, Elche, Alicante 03203, Spain.
García JA; Operational Research Center, Universidad Miguel Hernández, Elche, Alicante, Spain.
Agulló V; Hospital General Universitario de Elche, Camí de la Almazara 11, Elche, Alicante 03203, Spain.
García-Abellán J; Hospital General Universitario de Elche, Camí de la Almazara 11, Elche, Alicante 03203, Spain.
Telenti G; Hospital General Universitario de Elche, Camí de la Almazara 11, Elche, Alicante 03203, Spain.
Guillén L; Hospital General Universitario de Elche, Camí de la Almazara 11, Elche, Alicante 03203, Spain.
Gutiérrez F; Hospital General Universitario de Elche and Universidad Miguel Hernández, Camí de la Almazara 11, Elche, Alicante 03203, Spain. Electronic address: .
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Źródło :
EBioMedicine [EBioMedicine] 2020 Oct; Vol. 60, pp. 102999. Date of Electronic Publication: 2020 Sep 16.
Typ publikacji :
Journal Article
MeSH Terms :
Antibodies, Monoclonal, Humanized/*immunology
Betacoronavirus/*physiology
Coronavirus Infections/*pathology
Interleukin-6/*immunology
Pneumonia, Viral/*pathology
Aged ; Antibodies, Monoclonal, Humanized/therapeutic use ; Antibodies, Viral/blood ; Antibody Formation ; Betacoronavirus/isolation & purification ; Coronavirus Infections/drug therapy ; Coronavirus Infections/virology ; Female ; Humans ; Immunoglobulin G/blood ; Interleukin-6/analysis ; Kinetics ; Male ; Middle Aged ; Pandemics ; Pneumonia, Viral/drug therapy ; Pneumonia, Viral/virology ; Proportional Hazards Models ; Prospective Studies ; RNA, Viral/blood ; Viral Load
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Inhibition of interleukin-6 on matrix protein production by glomerular mesangial cells and the pathway involved.
Autorzy :
Chaudhari S; Department of Physiology and Anatomy, University of North Texas Health Science Center, Fort Worth, Texas.
Yazdizadeh Shotorbani P; Department of Physiology and Anatomy, University of North Texas Health Science Center, Fort Worth, Texas.
Tao Y; Department of Physiology and Anatomy, University of North Texas Health Science Center, Fort Worth, Texas.
Davis ME; Chemical Engineering, California Institute of Technology, Pasadena, California.
Mallet RT; Department of Physiology and Anatomy, University of North Texas Health Science Center, Fort Worth, Texas.
Ma R; Department of Physiology and Anatomy, University of North Texas Health Science Center, Fort Worth, Texas.
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Źródło :
American journal of physiology. Renal physiology [Am J Physiol Renal Physiol] 2020 Jun 01; Vol. 318 (6), pp. F1478-F1488. Date of Electronic Publication: 2020 May 11.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Extracellular Matrix Proteins/*metabolism
Interleukin-6/*metabolism
Mesangial Cells/*metabolism
Receptors, Interleukin-6/*metabolism
Animals ; Cells, Cultured ; Down-Regulation ; Extracellular Matrix Proteins/genetics ; Glucagon-Like Peptide-1 Receptor/genetics ; Glucagon-Like Peptide-1 Receptor/metabolism ; Humans ; Interleukin-6/genetics ; Male ; Mice, Inbred C57BL ; NF-kappa B/genetics ; NF-kappa B/metabolism ; ORAI1 Protein/genetics ; ORAI1 Protein/metabolism ; Receptors, Interleukin-6/genetics ; Signal Transduction
Czasopismo naukowe
Tytuł :
Role of Interleukin-6 in Lung Complications in Patients With COVID-19: Therapeutic Implications.
Autorzy :
Smetana K Jr; Institute of Anatomy, First Faculty of Medicine, Charles University, Prague, Czech Republic .; BIOCEV, Vestec, Czech Republic.
Brábek J; BIOCEV, Vestec, Czech Republic .; Department of Cell Biology, Faculty of Sciences, Charles University, Prague, Czech Republic.
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Źródło :
In vivo (Athens, Greece) [In Vivo] 2020 Jun; Vol. 34 (3 Suppl), pp. 1589-1592.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Coronavirus Infections/*complications
Cytokine Release Syndrome/*etiology
Interleukin-6/*physiology
Pneumonia, Viral/*complications
Anti-Inflammatory Agents/therapeutic use ; Antibodies, Monoclonal/therapeutic use ; Antibodies, Monoclonal, Humanized/therapeutic use ; Antiviral Agents/therapeutic use ; Clinical Trials as Topic ; Coronavirus Infections/drug therapy ; Coronavirus Infections/immunology ; Coronavirus Infections/physiopathology ; Cytokine Receptor gp130/antagonists & inhibitors ; Cytokine Receptor gp130/physiology ; Cytokine Release Syndrome/drug therapy ; Cytokine Release Syndrome/immunology ; Cytokine Release Syndrome/physiopathology ; Humans ; Immunotherapy ; Indoles/therapeutic use ; Interleukin-6/antagonists & inhibitors ; Lung/pathology ; Pandemics ; Pneumonia, Viral/drug therapy ; Pneumonia, Viral/immunology ; Pneumonia, Viral/physiopathology ; Receptors, Interleukin-6/antagonists & inhibitors ; Receptors, Interleukin-6/physiology ; Receptors, Virus/drug effects ; Signal Transduction
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Interleukin-6 and severe COVID-19: a systematic review and meta-analysis.
Autorzy :
Mojtabavi H; Universal Scientific Education and Research Network (USERN), Systematic Review and Meta-Analysis Expert Group (SRMEG), Tehran, Iran, Tehran University of Medical Sciences, Children's Medical Center, Research Center for Immunodeficiencies, Tehran, Iran.
Saghazadeh A; Universal Scientific Education and Research Network (USERN), Systematic Review and Meta-Analysis Expert Group (SRMEG), Tehran, Iran, Tehran University of Medical Sciences, Children's Medical Center, Research Center for Immunodeficiencies, Tehran, Iran.
Rezaei N; Tehran University of Medical Sciences, Children's Medical Center, Research Center for Immunodeficiencies, Tehran, Iran, Tehran University of Medical Sciences, School of Medicine, Department of Immunology, Tehran, Iran, Universal Scientific Education and Research Network (USERN), Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Tehran, Iran.
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Źródło :
European cytokine network [Eur Cytokine Netw] 2020 Jun 01; Vol. 31 (2), pp. 44-49.
Typ publikacji :
Journal Article; Meta-Analysis; Systematic Review
MeSH Terms :
Anti-Inflammatory Agents/*therapeutic use
Antibodies, Monoclonal, Humanized/*administration & dosage
Antiviral Agents/*therapeutic use
Betacoronavirus/*immunology
Coronavirus Infections/*drug therapy
Cytokine Release Syndrome/*drug therapy
Interleukin-6/*antagonists & inhibitors
Pneumonia, Viral/*drug therapy
Aged ; Betacoronavirus/pathogenicity ; Coronavirus Infections/immunology ; Coronavirus Infections/mortality ; Coronavirus Infections/virology ; Cytokine Release Syndrome/immunology ; Cytokine Release Syndrome/mortality ; Cytokine Release Syndrome/virology ; Female ; Gene Expression ; Humans ; Intensive Care Units ; Interleukin-6/genetics ; Interleukin-6/immunology ; Male ; Middle Aged ; Pandemics ; Pneumonia, Viral/immunology ; Pneumonia, Viral/mortality ; Pneumonia, Viral/virology ; Receptors, Interleukin-6/genetics ; Receptors, Interleukin-6/immunology ; Severity of Illness Index ; Survival Analysis ; Treatment Outcome
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Can we use interleukin-6 (IL-6) blockade for coronavirus disease 2019 (COVID-19)-induced cytokine release syndrome (CRS)?
Autorzy :
Liu B; Department of Metabolism and Endocrinology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China; National Clinical Research Center for Metabolic Diseases, Key Laboratory of Diabetes Immunology, Ministry of Education, Changsha, Hunan, China.
Li M; Department of Respiratory Medicine, Xiangya Hospital, Central South University, Changsha, Hunan, China; Xiangya Lung Cancer Center, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Zhou Z; Department of Metabolism and Endocrinology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China; National Clinical Research Center for Metabolic Diseases, Key Laboratory of Diabetes Immunology, Ministry of Education, Changsha, Hunan, China.
Guan X; Department of Internal Medicine, AdventHealth Orlando, Orlando, Florida, USA. Electronic address: .
Xiang Y; Department of Metabolism and Endocrinology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China; National Clinical Research Center for Metabolic Diseases, Key Laboratory of Diabetes Immunology, Ministry of Education, Changsha, Hunan, China. Electronic address: .
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Źródło :
Journal of autoimmunity [J Autoimmun] 2020 Jul; Vol. 111, pp. 102452. Date of Electronic Publication: 2020 Apr 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Antibodies, Monoclonal, Humanized/*therapeutic use
Coronavirus Infections/*pathology
Cytokine Release Syndrome/*therapy
Interleukin-6/*antagonists & inhibitors
Pneumonia, Viral/*pathology
Anti-Inflammatory Agents/therapeutic use ; Betacoronavirus/pathogenicity ; Humans ; Immunomodulation/drug effects ; Interleukin-6/blood ; Pandemics ; Severe Acute Respiratory Syndrome/pathology
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Serum interleukin-6 is an indicator for severity in 901 patients with SARS-CoV-2 infection: a cohort study.
Autorzy :
Zhang J; Department of Medical Oncology, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430079, Hubei, China.
Hao Y; Department of Rheumatology and Immunology, The First Hospital of Shanxi Medical University, Taiyuan, 030001, Shanxi, China.
Ou W; Department of Medical Oncology, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430079, Hubei, China.
Ming F; Department of Thoracic Surgery, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430079, Hubei, China.
Liang G; Department of Radiation Oncology, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430079, Hubei, China.
Qian Y; Department of Medical Oncology, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430079, Hubei, China.
Cai Q; Department of Medical Oncology, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430079, Hubei, China.
Dong S; Department of Medical Oncology, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430079, Hubei, China.
Hu S; Department of Medical Oncology, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430079, Hubei, China.
Wang W; Department of Hematological Oncology, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, No. 651 Dongfeng East Road, Yuexiu District, Guangzhou, 510060, Guangdong, China. .
Wei S; Department of Gastrointestinal Surgery & Colorectal Cancer Center of Hubei Province, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 116 Zhuodaoquan South Road, Hongshan District, Wuhan, 430079, Hubei, China. .
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Źródło :
Journal of translational medicine [J Transl Med] 2020 Oct 29; Vol. 18 (1), pp. 406. Date of Electronic Publication: 2020 Oct 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Coronavirus Infections/*blood
Coronavirus Infections/*drug therapy
Interleukin-6/*blood
Pneumonia, Viral/*blood
Pneumonia, Viral/*drug therapy
Aged ; Antibodies, Monoclonal, Humanized/administration & dosage ; Betacoronavirus ; Comorbidity ; Female ; Humans ; Kinetics ; Male ; Middle Aged ; Pandemics ; Propensity Score ; Retrospective Studies ; Treatment Outcome
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Early administration of interleukin-6 inhibitors for patients with severe COVID-19 disease is associated with decreased intubation, reduced mortality, and increased discharge.
Autorzy :
Sinha P; Section of Infectious Diseases, Department of Medicine, Boston University School of Medicine, Boston, MA, USA.
Mostaghim A; Department of Medicine, Boston University School of Medicine, Boston, MA, USA.
Bielick CG; Department of Medicine, Boston University School of Medicine, Boston, MA, USA.
McLaughlin A; Section of Infectious Diseases, Department of Medicine, Boston University School of Medicine, Boston, MA, USA.
Hamer DH; Section of Infectious Diseases, Department of Medicine, Boston University School of Medicine, Boston, MA, USA; Department of Global Health, Boston University School of Public Health, Boston, MA, USA.
Wetzler LM; Section of Infectious Diseases, Department of Medicine, Boston University School of Medicine, Boston, MA, USA.
Bhadelia N; Section of Infectious Diseases, Department of Medicine, Boston University School of Medicine, Boston, MA, USA; National Emerging Infectious Disease Laboratory, Boston, MA, USA.
Fagan MA; Section of Infectious Diseases, Department of Medicine, Boston University School of Medicine, Boston, MA, USA.
Linas BP; Section of Infectious Diseases, Department of Medicine, Boston University School of Medicine, Boston, MA, USA.
Assoumou SA; Section of Infectious Diseases, Department of Medicine, Boston University School of Medicine, Boston, MA, USA.
Ieong MH; Pulmonary Center, Boston University School of Medicine, Boston, MA, USA.
Lin NH; Section of Infectious Diseases, Department of Medicine, Boston University School of Medicine, Boston, MA, USA.
Cooper ER; Section of Pediatric Infectious Diseases, Boston Medical Center, Boston, MA, USA.
Brade KD; Department of Pharmacy, Boston Medical Center, Boston, MA, USA.
White LF; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
Barlam TF; Section of Infectious Diseases, Department of Medicine, Boston University School of Medicine, Boston, MA, USA.
Sagar M; Section of Infectious Diseases, Department of Medicine, Boston University School of Medicine, Boston, MA, USA. Electronic address: .
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Corporate Authors :
Boston Medical Center Covid-19 Treatment Panel
Źródło :
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases [Int J Infect Dis] 2020 Oct; Vol. 99, pp. 28-33. Date of Electronic Publication: 2020 Jul 25.
Typ publikacji :
Journal Article
MeSH Terms :
Betacoronavirus*
Antibodies, Monoclonal, Humanized/*therapeutic use
Coronavirus Infections/*drug therapy
Interleukin-6/*antagonists & inhibitors
Pneumonia, Viral/*drug therapy
Coronavirus Infections/mortality ; Coronavirus Infections/pathology ; Female ; Humans ; Intubation, Intratracheal ; Male ; Middle Aged ; Pandemics ; Patient Discharge ; Pneumonia, Viral/mortality ; Pneumonia, Viral/pathology ; Treatment Outcome
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Associations between serum amyloid A, interleukin-6, and COVID-19: A cross-sectional study.
Autorzy :
Liu Q; Department of Laboratory Medicine, The Second People's Hospital of Lianyungang, Lianyungang, China.
Dai Y; Department of Laboratory Medicine, Wuxi Fifth People's Hospital, Wuxi, China.
Feng M; Department of General Pediatrics, Zaozhuang Maternal and Child Health Hospital, Zaozhuang, China.
Wang X; Department of Laboratory Medicine, Wuxi Fifth People's Hospital, Wuxi, China.
Liang W; Department of Laboratory Medicine, The Second People's Hospital of Lianyungang, Lianyungang, China.
Yang F; Department of Laboratory Medicine, The Second People's Hospital of Lianyungang, Lianyungang, China.
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Źródło :
Journal of clinical laboratory analysis [J Clin Lab Anal] 2020 Oct; Vol. 34 (10), pp. e23527. Date of Electronic Publication: 2020 Aug 28.
Typ publikacji :
Journal Article
MeSH Terms :
Coronavirus Infections*/blood
Coronavirus Infections*/diagnosis
Coronavirus Infections*/epidemiology
Pandemics*
Pneumonia, Viral*/blood
Pneumonia, Viral*/diagnosis
Pneumonia, Viral*/epidemiology
Interleukin-6/*blood
Serum Amyloid A Protein/*analysis
Adult ; Betacoronavirus ; Cross-Sectional Studies ; Female ; Humans ; Male ; Middle Aged ; ROC Curve ; Risk Factors
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Elevated interleukin-6 and adverse outcomes in COVID-19 patients: a meta-analysis based on adjusted effect estimates.
Autorzy :
Zhang P; Department of Epidemiology, College of Public Health, Zhengzhou University, Zhengzhou, 450001, China.
Shi L; Department of Epidemiology, College of Public Health, Zhengzhou University, Zhengzhou, 450001, China.
Xu J; Department of Epidemiology, College of Public Health, Zhengzhou University, Zhengzhou, 450001, China.
Wang Y; Department of Toxicology, Henan Center for Disease Control and Prevention, Zhengzhou, 450016, China.
Yang H; Department of Epidemiology, College of Public Health, Zhengzhou University, Zhengzhou, 450001, China. .
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Źródło :
Immunogenetics [Immunogenetics] 2020 Oct; Vol. 72 (8), pp. 431-437. Date of Electronic Publication: 2020 Oct 17.
Typ publikacji :
Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't
MeSH Terms :
Coronavirus Infections/*epidemiology
Coronavirus Infections/*pathology
Interleukin-6/*blood
Pneumonia, Viral/*epidemiology
Pneumonia, Viral/*pathology
Betacoronavirus ; Biomarkers/blood ; Humans ; Pandemics ; Prognosis ; Risk Factors
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Interleukin-6 role in the severity of COVID-19 and intensive care unit stay length.
Autorzy :
Taher Al Barzin RMG; Microbiology Unit, Department of Basic Science, College of Medicine, Hawler Medical University, Erbil, Kurdistan Region-Iraq.
Ghafour Raheem S; Microbiology Unit, Department of Basic Science, College of Medicine, Hawler Medical University, Erbil, Kurdistan Region-Iraq.
Khudhur PK; Microbiology Unit, Department of Basic Science, College of Medicine, Hawler Medical University, Erbil, Kurdistan Region-Iraq.
Abdulkarimi R; Department of Environment, Boukan Office, West Azerbaijan Province, Iran.
Mohammadnejad E; Nursing Education, Department of Medical-Surgical Nursing and Basic Sciences, School of Nursing & Midwifery, Tehran University of Medical Sciences, Tehran, Iran.
Tabatabaee A; Nursing Department, Quchan Branch, Islamic Azad University, Quchan, Iran.
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Źródło :
Cellular and molecular biology (Noisy-le-Grand, France) [Cell Mol Biol (Noisy-le-grand)] 2020 Sep 30; Vol. 66 (6), pp. 15-18. Date of Electronic Publication: 2020 Sep 30.
Typ publikacji :
Journal Article
MeSH Terms :
Intensive Care Units*
Length of Stay*
Severity of Illness Index*
Betacoronavirus/*genetics
Coronavirus Infections/*epidemiology
Interleukin-6/*blood
Pneumonia, Viral/*epidemiology
Adult ; Coronavirus Infections/virology ; Cross-Sectional Studies ; Energy Intake ; Female ; Humans ; Male ; Middle Aged ; Nutritional Status ; Pandemics ; Pneumonia, Viral/virology ; Real-Time Polymerase Chain Reaction ; Serum Albumin, Human/analysis
SCR Disease Name :
COVID-19
Czasopismo naukowe

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