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Wyszukujesz frazę ""Interleukin-6"" wg kryterium: Temat


Tytuł:
Mechanistic computational modeling of monospecific and bispecific antibodies targeting interleukin-6/8 receptors.
Autorzy:
Ray CMP; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.; Medical-Scientist Training Program, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.; Institute for Computational Medicine, Johns Hopkins University, Baltimore, Maryland, United States of America.
Yang H; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, Maryland, United States of America.; Translational Tissue Engineering Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.
Spangler JB; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, Maryland, United States of America.; Translational Tissue Engineering Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.; Sidney Kimmel Cancer Center, Johns Hopkins University, Baltimore, Maryland, United States of America.; Bloomberg Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University, Baltimore, Maryland, United States of America.; Department of Ophthalmology, Johns Hopkins School of Medicine, Baltimore, Maryland, United States of America.
Mac Gabhann F; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.; Institute for Computational Medicine, Johns Hopkins University, Baltimore, Maryland, United States of America.; Institute for Nano Biotechnology (INBT), Johns Hopkins University, Baltimore, Maryland, United States of America.
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Źródło:
PLoS computational biology [PLoS Comput Biol] 2024 Jun 07; Vol. 20 (6), pp. e1012157. Date of Electronic Publication: 2024 Jun 07 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Antibodies, Bispecific*/pharmacology
Antibodies, Bispecific*/immunology
Antibodies, Bispecific*/chemistry
Receptors, Interleukin-6*/antagonists & inhibitors
Receptors, Interleukin-6*/immunology
Receptors, Interleukin-6*/metabolism
Receptors, Interleukin-8*/metabolism
Receptors, Interleukin-8*/antagonists & inhibitors
Humans ; Animals ; Computational Biology ; Computer Simulation ; Interleukin-6/metabolism ; Interleukin-6/immunology ; Mice ; Interleukin-8/metabolism ; Interleukin-8/immunology ; Interleukin-8/antagonists & inhibitors ; Neoplasms/immunology ; Neoplasms/drug therapy
Czasopismo naukowe
Tytuł:
Autocrine Regulation of Interleukin-6 via the Activation of STAT3 and Akt in Cardiac Myxoma Cells.
Autorzy:
Jougasaki M; Institute for Clinical Research, NHO Kagoshima Medical Center, Kagoshima 892-0853, Japan.
Takenoshita Y; Institute for Clinical Research, NHO Kagoshima Medical Center, Kagoshima 892-0853, Japan.
Umebashi K; Institute for Clinical Research, NHO Kagoshima Medical Center, Kagoshima 892-0853, Japan.
Yamamoto M; Institute for Clinical Research, NHO Kagoshima Medical Center, Kagoshima 892-0853, Japan.
Sudou K; Institute for Clinical Research, NHO Kagoshima Medical Center, Kagoshima 892-0853, Japan.
Nakashima H; Institute for Clinical Research, NHO Kagoshima Medical Center, Kagoshima 892-0853, Japan.
Sonoda M; Institute for Clinical Research, NHO Kagoshima Medical Center, Kagoshima 892-0853, Japan.
Kinjo T; Institute for Clinical Research, NHO Kagoshima Medical Center, Kagoshima 892-0853, Japan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 13; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 13.
Typ publikacji:
Journal Article
MeSH Terms:
Interleukin-6*/metabolism
Myxoma*/metabolism
Humans ; Cells, Cultured ; Proto-Oncogene Proteins c-akt/metabolism ; Receptors, Interleukin-6/metabolism ; Signal Transduction ; STAT3 Transcription Factor/metabolism
Czasopismo naukowe
Tytuł:
Nonspecific Inhibition of IL6 Family Cytokine Signalling by Soluble gp130.
Autorzy:
Widjaja AA; Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School, 8 College Road, Singapore 169857, Singapore.
Cook SA; Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School, 8 College Road, Singapore 169857, Singapore.; National Heart Centre Singapore, National Heart Research Institute Singapore, Singapore 169609, Singapore.; MRC-London Institute of Medical Sciences, Hammersmith Hospital Campus, London W6 8RF, UK.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 23; Vol. 25 (3). Date of Electronic Publication: 2024 Jan 23.
Typ publikacji:
Journal Article
MeSH Terms:
Cytokines*/pharmacology
Interleukin-6*/metabolism
Mice ; Humans ; Animals ; Cytokine Receptor gp130/metabolism ; Signal Transduction ; Receptors, Interleukin-6
Czasopismo naukowe
Tytuł:
Associations between serum estradiol and IL-6/sIL-6R/sgp130 complex in female patients with major depressive disorder.
Autorzy:
Sun T; Department of Clinical Laboratory, Renmin Hospital of Wuhan University, Zhangzhidong Road, Wuchang District, Wuhan, 430060, Hubei, China.
Chen Q; Department of Clinical Laboratory, Renmin Hospital of Wuhan University, Zhangzhidong Road, Wuchang District, Wuhan, 430060, Hubei, China.
Mei J; Department of Clinical Laboratory, Renmin Hospital of Wuhan University, Zhangzhidong Road, Wuchang District, Wuhan, 430060, Hubei, China.
Li Y; Department of Clinical Laboratory, Renmin Hospital of Wuhan University, Zhangzhidong Road, Wuchang District, Wuhan, 430060, Hubei, China. .
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Źródło:
BMC psychiatry [BMC Psychiatry] 2023 Oct 12; Vol. 23 (1), pp. 742. Date of Electronic Publication: 2023 Oct 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Depressive Disorder, Major*/diagnosis
Receptors, Interleukin-6*
Female ; Humans ; Biomarkers ; Cytokine Receptor gp130 ; Estradiol ; Interleukin-6
Czasopismo naukowe
Tytuł:
An epithelial gene signature of trans-IL-6 signaling defines a subgroup of type 2-low asthma.
Autorzy:
El-Husseini ZW; Department of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children's Hospital, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD (GRIAC), Groningen, The Netherlands.; Department of Molecular Pharmacology, Faculty of Science and Engineering, Groningen Research Institute of Pharmacy, University of Groningen, 9713 AV, Groningen, The Netherlands.
Khalenkow D; Department of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children's Hospital, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD (GRIAC), Groningen, The Netherlands.
Lan A; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD (GRIAC), Groningen, The Netherlands.; Department of Molecular Pharmacology, Faculty of Science and Engineering, Groningen Research Institute of Pharmacy, University of Groningen, 9713 AV, Groningen, The Netherlands.
van der Molen T; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD (GRIAC), Groningen, The Netherlands.
Brightling C; Department of Infection, Immunity and Inflammation, Institute for Lung Health, University of Leicester, Leicester, UK.
Papi A; Department of Respiratory Medicine, University of Ferrara, Ferrara, Italy.
Rabe KF; Department of Medicine, Christian Albrechts University Kiel, Kiel and Lungen Clinic Grosshansdorf (Members of the German Center for Lung Research (DZL)), Grosshansdorf, Germany.
Siddiqui S; National Heart and Lung Institute, Imperial College and Imperial NIHR Biomedical Research Centre, London, UK.
Singh D; Medicines Evaluation Unit, Manchester University NHS Foundation Hospital Trust, University of Manchester, Manchester, UK.
Kraft M; Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, USA.
Beghe B; University of Modena and Reggio Emilia, AOU of Modena, Modena, Italy.
van den Berge M; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD (GRIAC), Groningen, The Netherlands.; Department of Pulmonary Diseases, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
van Gosliga D; Department of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children's Hospital, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD (GRIAC), Groningen, The Netherlands.; Department of Pathology and Medical Biology, Experimental Pulmonary and Inflammatory Research (EXPIRE), University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands.
Nawijn MC; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD (GRIAC), Groningen, The Netherlands.; Department of Pathology and Medical Biology, Experimental Pulmonary and Inflammatory Research (EXPIRE), University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands.
Rose-John S; Biochemical Institute, University of Kiel, Kiel, Germany.
Koppelman GH; Department of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children's Hospital, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD (GRIAC), Groningen, The Netherlands.
Gosens R; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD (GRIAC), Groningen, The Netherlands. .; Department of Molecular Pharmacology, Faculty of Science and Engineering, Groningen Research Institute of Pharmacy, University of Groningen, 9713 AV, Groningen, The Netherlands. .
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Źródło:
Respiratory research [Respir Res] 2023 Dec 07; Vol. 24 (1), pp. 308. Date of Electronic Publication: 2023 Dec 07.
Typ publikacji:
Journal Article
MeSH Terms:
Asthma*/diagnosis
Asthma*/drug therapy
Asthma*/genetics
Interleukin-6*/metabolism
Humans ; Cytokine Receptor gp130/genetics ; Cytokine Receptor gp130/metabolism ; Inflammation ; Receptors, Interleukin-6/genetics ; Receptors, Interleukin-6/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł:
Association of Polymorphisms of IL-6 Pathway Genes (IL6, IL6R and IL6ST) with COVID-19 Severity in an Amazonian Population.
Autorzy:
Rodrigues FBB; Laboratório de Genética de Doenças Complexas, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 58255-000, Brazil.; Programa de Pós-Graduação em Biologia de Agentes Infecciosos e Parasitários, Universidade Federal do Pará, Belém 58255-000, Brazil.
da Silva R; Laboratório de Genética de Doenças Complexas, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 58255-000, Brazil.; Programa de Pós-Graduação em Biologia de Agentes Infecciosos e Parasitários, Universidade Federal do Pará, Belém 58255-000, Brazil.
Santos EFD; Laboratório de Genética de Doenças Complexas, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 58255-000, Brazil.; Programa de Pós-Graduação em Biologia de Agentes Infecciosos e Parasitários, Universidade Federal do Pará, Belém 58255-000, Brazil.
de Brito MTFM; Laboratório de Genética de Doenças Complexas, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 58255-000, Brazil.
da Silva ALS; Laboratório de Genética de Doenças Complexas, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 58255-000, Brazil.
de Meira Leite M; Laboratório de Genética de Doenças Complexas, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 58255-000, Brazil.
Póvoa da Costa F; Laboratório de Genética de Doenças Complexas, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 58255-000, Brazil.; Programa de Pós-Graduação em Biologia de Agentes Infecciosos e Parasitários, Universidade Federal do Pará, Belém 58255-000, Brazil.
de Nazaré do Socorro de Almeida Viana M; Laboratório de Genética de Doenças Complexas, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 58255-000, Brazil.; Programa de Pós-Graduação em Biologia de Agentes Infecciosos e Parasitários, Universidade Federal do Pará, Belém 58255-000, Brazil.
de Sarges KML; Laboratório de Genética de Doenças Complexas, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 58255-000, Brazil.; Programa de Pós-Graduação em Biologia de Agentes Infecciosos e Parasitários, Universidade Federal do Pará, Belém 58255-000, Brazil.
Cantanhede MHD; Laboratório de Genética de Doenças Complexas, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 58255-000, Brazil.; Programa de Pós-Graduação em Biologia de Agentes Infecciosos e Parasitários, Universidade Federal do Pará, Belém 58255-000, Brazil.
Veríssimo AOL; Hospital Adventista de Belém, Belém 66093-681, Brazil.
Carvalho MDS; Hospital Adventista de Belém, Belém 66093-681, Brazil.
Henriques DF; Seção de Arbovirologia e Febres Hemorrágicas, Instituto Evandro Chagas, Secretaria de Vigilância em Saúde, Ministério da Saúde do Brasil, Ananindeua 67000-000, Brazil.
Silva CPD; Seção de Arbovirologia e Febres Hemorrágicas, Instituto Evandro Chagas, Secretaria de Vigilância em Saúde, Ministério da Saúde do Brasil, Ananindeua 67000-000, Brazil.
Costa IB; Laboratório de Imunologia, Seção de Virologia, Instituto Evandro Chagas, Secretaria de Vigilância em Saúde, Ministério da Saúde do Brasil, Ananindeua 67000-000, Brazil.
Nunes JAL; Laboratório de Imunologia, Seção de Virologia, Instituto Evandro Chagas, Secretaria de Vigilância em Saúde, Ministério da Saúde do Brasil, Ananindeua 67000-000, Brazil.
Costa IB; Laboratório de Imunologia, Seção de Virologia, Instituto Evandro Chagas, Secretaria de Vigilância em Saúde, Ministério da Saúde do Brasil, Ananindeua 67000-000, Brazil.
Viana GMR; Laboratório de Pesquisas Básicas em Malária, Seção de Parasitologia, Instituto Evandro Chagas, secretaria de Vigilância em Saúde, Ministério da Saúde do Brasil, Ananindeua 67000-000, Brazil.
Queiroz MAF; Laboratório de Virologia, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 58255-000, Brazil.
Lima SS; Laboratório de Virologia, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 58255-000, Brazil.
Lopes JDC; Programa de Pós-Graduação em Biologia de Agentes Infecciosos e Parasitários, Universidade Federal do Pará, Belém 58255-000, Brazil.; Laboratório de Virologia, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 58255-000, Brazil.
Torres MKDS; Programa de Pós-Graduação em Biologia de Agentes Infecciosos e Parasitários, Universidade Federal do Pará, Belém 58255-000, Brazil.; Laboratório de Virologia, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 58255-000, Brazil.
Vallinoto IMVC; Programa de Pós-Graduação em Biologia de Agentes Infecciosos e Parasitários, Universidade Federal do Pará, Belém 58255-000, Brazil.; Laboratório de Virologia, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 58255-000, Brazil.
Bichara CDA; Programa de Pós-Graduação em Biologia de Agentes Infecciosos e Parasitários, Universidade Federal do Pará, Belém 58255-000, Brazil.; Laboratório de Virologia, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 58255-000, Brazil.
Vallinoto ACR; Laboratório de Virologia, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 58255-000, Brazil.
Santos EJMD; Laboratório de Genética de Doenças Complexas, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 58255-000, Brazil.
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Źródło:
Viruses [Viruses] 2023 May 19; Vol. 15 (5). Date of Electronic Publication: 2023 May 19.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Interleukin-6*/genetics
COVID-19*/genetics
Humans ; Cross-Sectional Studies ; Receptors, Interleukin-6/genetics ; Genotype ; Polymorphism, Single Nucleotide ; Genetic Predisposition to Disease ; Cytokine Receptor gp130/genetics
Czasopismo naukowe
Tytuł:
Causal relationship of interleukin-6 and its receptor on sarcopenia traits using mendelian randomization.
Autorzy:
Chen B; Department of Development and Regeneration, KU Leuven, Leuven, Belgium.
Li S; Wuxi Affiliated Hospital of Nanjing University of Chinese Medicine, Wuxi, China.
Lin S; Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, China.
Dong H; Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, China. .; Department of traumatology, The First Affiliated Hospital, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, China. .
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Źródło:
Nutrition journal [Nutr J] 2024 May 15; Vol. 23 (1), pp. 51. Date of Electronic Publication: 2024 May 15.
Typ publikacji:
Journal Article
MeSH Terms:
Interleukin-6*/genetics
Interleukin-6*/blood
Sarcopenia*/genetics
Mendelian Randomization Analysis*/methods
Polymorphism, Single Nucleotide*
Receptors, Interleukin-6*/genetics
Hand Strength*/physiology
Genome-Wide Association Study*/methods
Humans
Czasopismo naukowe
Tytuł:
No Association of Polymorphisms in the Genes Encoding Interleukin-6 and Interleukin-6 Receptor Subunit Alpha with the Risk of Keloids in Polish Patients.
Autorzy:
Dmytrzak A; Aesthetic Med, 71-403 Szczecin, Poland.
Lewandowska K; Department of Clinical and Molecular Biochemistry, Pomeranian Medical University, 70-111 Szczecin, Poland.
Boroń A; Department of Clinical and Molecular Biochemistry, Pomeranian Medical University, 70-111 Szczecin, Poland.
Łoniewska B; Department of Neonatal Diseases, Pomeranian Medical University, 70-111 Szczecin, Poland.
Grzesch N; Department of Clinical and Molecular Biochemistry, Pomeranian Medical University, 70-111 Szczecin, Poland.
Brodkiewicz A; Department of Pediatrics, Child Nephrology, Dialysotherapy and Management of Acute Poisoning, Pomeranian Medical University, 70-780 Szczecin, Poland.
Clark JSC; Department of Clinical and Molecular Biochemistry, Pomeranian Medical University, 70-111 Szczecin, Poland.
Ciechanowicz A; Department of Clinical and Molecular Biochemistry, Pomeranian Medical University, 70-111 Szczecin, Poland.
Kostrzewa-Nowak D; Department of Clinical and Molecular Biochemistry, Pomeranian Medical University, 70-111 Szczecin, Poland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 May 13; Vol. 25 (10). Date of Electronic Publication: 2024 May 13.
Typ publikacji:
Journal Article
MeSH Terms:
Keloid*/genetics
Keloid*/pathology
Interleukin-6*/genetics
Receptors, Interleukin-6*/genetics
Polymorphism, Single Nucleotide*
Genetic Predisposition to Disease*
Humans ; Male ; Female ; Adult ; Poland ; Middle Aged ; Promoter Regions, Genetic ; Case-Control Studies ; Haplotypes ; Alleles ; Adolescent ; Young Adult ; Gene Frequency ; Genotype ; Infant, Newborn ; Genetic Association Studies
Czasopismo naukowe
Tytuł:
Left atrial volume index and interleukin-6 as predictors for postoperative atrial fibrillation.
Autorzy:
Tao H; Department of Critical Care Medicine, Nanjing First Hospital, Nanjing Medical University, 68 Changle Road, Nanjing, Jiangsu Province, 210006, China.
Shen X; Department of Critical Care Medicine, Nanjing First Hospital, Nanjing Medical University, 68 Changle Road, Nanjing, Jiangsu Province, 210006, China.
Zou L; Department of Critical Care Medicine, Nanjing First Hospital, Nanjing Medical University, 68 Changle Road, Nanjing, Jiangsu Province, 210006, China.
Zhang C; Department of Critical Care Medicine, Nanjing First Hospital, Nanjing Medical University, 68 Changle Road, Nanjing, Jiangsu Province, 210006, China. .
Hong L; Department of Critical Care Medicine, Nanjing First Hospital, Nanjing Medical University, 68 Changle Road, Nanjing, Jiangsu Province, 210006, China. .
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Źródło:
Journal of cardiothoracic surgery [J Cardiothorac Surg] 2024 Jun 07; Vol. 19 (1), pp. 325. Date of Electronic Publication: 2024 Jun 07.
Typ publikacji:
Journal Article
MeSH Terms:
Atrial Fibrillation*/etiology
Interleukin-6*/blood
Postoperative Complications*/diagnosis
Cardiac Surgical Procedures*/adverse effects
Heart Atria*/diagnostic imaging
Humans ; Female ; Male ; Middle Aged ; Aged ; Predictive Value of Tests ; Retrospective Studies ; Risk Factors ; Biomarkers/blood ; ROC Curve
Czasopismo naukowe
Tytuł:
The fibroid phenotype of biological naïve patients with rheumatoid arthritis are less likely to respond to anti-IL-6R treatment.
Autorzy:
Madsen SF; Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark. .; ImmunoScience, Nordic Bioscience, Herlev Hovedgade 205, 2730, Herlev, Denmark. .
Sinkeviciute D; ImmunoScience, Nordic Bioscience, Herlev Hovedgade 205, 2730, Herlev, Denmark.
Thudium CS; ImmunoScience, Nordic Bioscience, Herlev Hovedgade 205, 2730, Herlev, Denmark.
Karsdal MA; ImmunoScience, Nordic Bioscience, Herlev Hovedgade 205, 2730, Herlev, Denmark.
Bay-Jensen AC; ImmunoScience, Nordic Bioscience, Herlev Hovedgade 205, 2730, Herlev, Denmark.
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Źródło:
Scientific reports [Sci Rep] 2024 May 10; Vol. 14 (1), pp. 10751. Date of Electronic Publication: 2024 May 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Arthritis, Rheumatoid*/drug therapy
Arthritis, Rheumatoid*/metabolism
Arthritis, Rheumatoid*/pathology
Receptors, Interleukin-6*/metabolism
Receptors, Interleukin-6*/antagonists & inhibitors
Antibodies, Monoclonal, Humanized*/therapeutic use
Antirheumatic Agents*/therapeutic use
Humans ; Female ; Male ; Middle Aged ; Methotrexate/therapeutic use ; Phenotype ; Biomarkers ; Adult ; Aged ; Treatment Outcome
Czasopismo naukowe
Tytuł:
Targeting interleukin-6 as a treatment approach for peritoneal carcinomatosis.
Autorzy:
Dadgar N; Translational Hematology & Oncology Research, Enterprise Cancer Institute, Cleveland Clinic, Cleveland, OH, 44106, USA.
Sherry C; Allegheny Health Network Cancer Institute, 314 E. North Ave, Pittsburgh, PA, 15212, USA.
Zimmerman J; Allegheny Health Network Cancer Institute, 314 E. North Ave, Pittsburgh, PA, 15212, USA.
Park H; Allegheny Health Network Cancer Institute, 314 E. North Ave, Pittsburgh, PA, 15212, USA.
Lewis C; Allegheny Health Network Cancer Institute, 314 E. North Ave, Pittsburgh, PA, 15212, USA.
Donnenberg A; Allegheny Health Network Cancer Institute, 314 E. North Ave, Pittsburgh, PA, 15212, USA.
Zaidi AH; Allegheny Health Network Cancer Institute, 314 E. North Ave, Pittsburgh, PA, 15212, USA.
Fan Y; Allegheny Health Network Cancer Institute, 314 E. North Ave, Pittsburgh, PA, 15212, USA.
Xiao K; Center for Proteomics & Artificial Intelligence, Center for Clinical Mass Spectrometry, Allegheny Health Network Cancer Institute, Pittsburgh, PA, 15224, USA.
Bartlett D; Allegheny Health Network Cancer Institute, 314 E. North Ave, Pittsburgh, PA, 15212, USA.
Donnenberg V; University of Pittsburgh School of MedicineDepartment of Cardiothoracic SurgeryUPMC Hillman Cancer Center Wagner, Patrick; Allegheny Health Network Cancer Institute, Pittsburgh, USA.
Wagner PL; Allegheny Health Network Cancer Institute, 314 E. North Ave, Pittsburgh, PA, 15212, USA. .
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Źródło:
Journal of translational medicine [J Transl Med] 2024 Apr 30; Vol. 22 (1), pp. 402. Date of Electronic Publication: 2024 Apr 30.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Peritoneal Neoplasms*/drug therapy
Peritoneal Neoplasms*/secondary
Interleukin-6*/metabolism
Interleukin-6*/antagonists & inhibitors
Humans ; Animals ; Molecular Targeted Therapy ; Signal Transduction
Czasopismo naukowe
Tytuł:
Cholesterol-Modified Anti-Il6 siRNA Reduces the Severity of Acute Lung Injury in Mice.
Autorzy:
Chernikov IV; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Acad. Lavrentiev Ave. 8, 630090 Novosibirsk, Russia.
Bachkova IK; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Acad. Lavrentiev Ave. 8, 630090 Novosibirsk, Russia.; Faculty of Natural Sciences, Novosibirsk State University, Pirogova Str., 1, 630090 Novosibirsk, Russia.
Sen'kova AV; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Acad. Lavrentiev Ave. 8, 630090 Novosibirsk, Russia.
Meschaninova MI; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Acad. Lavrentiev Ave. 8, 630090 Novosibirsk, Russia.
Savin IA; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Acad. Lavrentiev Ave. 8, 630090 Novosibirsk, Russia.
Vlassov VV; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Acad. Lavrentiev Ave. 8, 630090 Novosibirsk, Russia.
Zenkova MA; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Acad. Lavrentiev Ave. 8, 630090 Novosibirsk, Russia.
Chernolovskaya EL; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Acad. Lavrentiev Ave. 8, 630090 Novosibirsk, Russia.
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Źródło:
Cells [Cells] 2024 Apr 30; Vol. 13 (9). Date of Electronic Publication: 2024 Apr 30.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
RNA, Small Interfering*/metabolism
RNA, Small Interfering*/genetics
Acute Lung Injury*/therapy
Acute Lung Injury*/genetics
Acute Lung Injury*/pathology
Acute Lung Injury*/metabolism
Interleukin-6*/metabolism
Interleukin-6*/genetics
Cholesterol*/metabolism
Animals ; Mice ; Lipopolysaccharides ; Male ; Disease Models, Animal ; Mice, Inbred C57BL ; Cell Line ; Lung/pathology ; Lung/metabolism
Czasopismo naukowe
Tytuł:
Investigating the Impact of IL6 on Insulin Secretion: Evidence from INS-1 Cells, Human Pancreatic Islets, and Serum Analysis.
Autorzy:
Taneera J; College of Medicine, University of Sharjah, Sharjah P.O. Box 27272, United Arab Emirates.; Research Institute of Medical and Health Sciences, University of Sharjah, Sharjah P.O. Box 27272, United Arab Emirates.
Khalique A; Research Institute of Medical and Health Sciences, University of Sharjah, Sharjah P.O. Box 27272, United Arab Emirates.
Mohammed AK; Research Institute of Medical and Health Sciences, University of Sharjah, Sharjah P.O. Box 27272, United Arab Emirates.
Mussa BM; College of Medicine, University of Sharjah, Sharjah P.O. Box 27272, United Arab Emirates.; Research Institute of Medical and Health Sciences, University of Sharjah, Sharjah P.O. Box 27272, United Arab Emirates.
Sulaiman N; College of Medicine, University of Sharjah, Sharjah P.O. Box 27272, United Arab Emirates.; Research Institute of Medical and Health Sciences, University of Sharjah, Sharjah P.O. Box 27272, United Arab Emirates.
Abu-Gharbieh E; College of Medicine, University of Sharjah, Sharjah P.O. Box 27272, United Arab Emirates.; Research Institute of Medical and Health Sciences, University of Sharjah, Sharjah P.O. Box 27272, United Arab Emirates.; School of Pharmacy, The University of Jordan, Amman 11942, Jordan.
El-Huneidi W; College of Medicine, University of Sharjah, Sharjah P.O. Box 27272, United Arab Emirates.; Research Institute of Medical and Health Sciences, University of Sharjah, Sharjah P.O. Box 27272, United Arab Emirates.
Saber-Ayad MM; College of Medicine, University of Sharjah, Sharjah P.O. Box 27272, United Arab Emirates.; Research Institute of Medical and Health Sciences, University of Sharjah, Sharjah P.O. Box 27272, United Arab Emirates.
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Źródło:
Cells [Cells] 2024 Apr 15; Vol. 13 (8). Date of Electronic Publication: 2024 Apr 15.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Interleukin-6*/metabolism
Interleukin-6*/blood
Insulin Secretion*/drug effects
Islets of Langerhans*/metabolism
Islets of Langerhans*/drug effects
Diabetes Mellitus, Type 2*/metabolism
Diabetes Mellitus, Type 2*/blood
Humans ; Male ; Middle Aged ; Female ; Adult ; Glucose/metabolism ; Insulin/metabolism ; Insulin/blood ; Rats ; Insulin-Secreting Cells/metabolism ; Insulin-Secreting Cells/drug effects ; Animals ; Cell Line ; Aged ; Apoptosis/drug effects
Czasopismo naukowe
Tytuł:
Constitutive knockout of interleukin-6 ameliorates memory deficits and entorhinal astrocytosis in the MRL/lpr mouse model of neuropsychiatric lupus.
Autorzy:
Reynolds J; Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York, NY, USA.
Huang M; Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York, NY, USA.
Li Y; University of Houston, Houston, TX, USA.
Meineck M; University Medical Center of the Johannes Gutenberg University, University of Mainz, Mainz, Germany.
Moeckel T; University Medical Center of the Johannes Gutenberg University, University of Mainz, Mainz, Germany.
Weinmann-Menke J; University Medical Center of the Johannes Gutenberg University, University of Mainz, Mainz, Germany.
Mohan C; University of Houston, Houston, TX, USA.
Schwarting A; University Medical Center of the Johannes Gutenberg University, University of Mainz, Mainz, Germany.
Putterman C; Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York, NY, USA. .; Azrieli Faculty of Medicine, Bar-Ilan University, Zefat, Israel. .
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Źródło:
Journal of neuroinflammation [J Neuroinflammation] 2024 Apr 10; Vol. 21 (1), pp. 89. Date of Electronic Publication: 2024 Apr 10.
Typ publikacji:
Journal Article
MeSH Terms:
Interleukin-6*/genetics
Lupus Erythematosus, Systemic*
Lupus Vasculitis, Central Nervous System*
Animals ; Mice ; Depression ; Gliosis ; Memory Disorders/genetics ; Mice, Inbred MRL lpr
Czasopismo naukowe
Tytuł:
Interferon-γ Induces Interleukin-6 Production and Alpha-smooth Muscle Actin Expression in Systemic Sclerosis Fibroblasts.
Autorzy:
Rokni M; Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran AND Rheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran AND Department of Immunology, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran. .
Farhadi E; Rheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran AND Research Center for Chronic Inflammatory Diseases, Tehran University of Medical Sciences, Tehran, Iran. .
Kavosi H; Tobacco Prevention and Control Research Center (TPCRC), National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran. .
Akhtari M; Rheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran AND Research Center for Chronic Inflammatory Diseases, Tehran University of Medical Sciences, Tehran, Iran. .
Madreseh E; Rheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran AND Research Center for Chronic Inflammatory Diseases, Tehran University of Medical Sciences, Tehran, Iran. .
Enayati S; Rheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran. .
Sadeghi Shaker M; Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran AND Rheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran. .
Mostafaei S; Rheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran. .
Gharibdoost F; Rheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran. .
Mahmoudi M; Rheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran AND Research Center for Chronic Inflammatory Diseases, Tehran University of Medical Sciences, Tehran, Iran. .
Vodjgani M; Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. .
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Źródło:
Iranian journal of allergy, asthma, and immunology [Iran J Allergy Asthma Immunol] 2024 Apr 07; Vol. 23 (2), pp. 197-220. Date of Electronic Publication: 2024 Apr 07.
Typ publikacji:
Journal Article
MeSH Terms:
Actins*/metabolism
Actins*/genetics
Fibroblasts*/metabolism
Fibroblasts*/pathology
Fibroblasts*/drug effects
Interferon-gamma*/pharmacology
Interleukin-6*/metabolism
Interleukin-6*/genetics
Scleroderma, Systemic*/metabolism
Scleroderma, Systemic*/pathology
Scleroderma, Systemic*/immunology
Adult ; Female ; Humans ; Male ; Middle Aged ; Cells, Cultured ; Dexamethasone/pharmacology ; Fibrosis ; Gene Expression Regulation/drug effects ; Interferon Regulatory Factor-1/metabolism ; Interferon Regulatory Factor-1/genetics ; Myofibroblasts/metabolism ; Myofibroblasts/pathology
Czasopismo naukowe
Tytuł:
Interleukin-6 signaling requires EHD1-mediated alteration of membrane rafts.
Autorzy:
Woo JH; Inflamm-aging Translational Research Center, Ajou University School of Medicine, Suwon, Korea.
Park SJ; Inflamm-aging Translational Research Center, Ajou University School of Medicine, Suwon, Korea.
Park SM; Department of Pharmacology, Ajou University School of Medicine, Suwon, Korea.; Center for Convergence Research of Neurological Disorders, Ajou University School of Medicine, Suwon, Korea.
Joe EH; Department of Pharmacology, Ajou University School of Medicine, Suwon, Korea.; Center for Convergence Research of Neurological Disorders, Ajou University School of Medicine, Suwon, Korea.
Jou I; Inflamm-aging Translational Research Center, Ajou University School of Medicine, Suwon, Korea.; Department of Pharmacology, Ajou University School of Medicine, Suwon, Korea.
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Źródło:
The FEBS journal [FEBS J] 2022 Oct; Vol. 289 (19), pp. 5914-5932. Date of Electronic Publication: 2022 Apr 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cholera Toxin*/metabolism
Interleukin-6*/genetics
Interleukin-6*/metabolism
Cholesterol/metabolism ; Cytokine Receptor gp130/genetics ; Cytokine Receptor gp130/metabolism ; Membrane Microdomains/metabolism ; Membrane Proteins/metabolism ; Receptors, Interleukin-6/genetics ; Receptors, Interleukin-6/metabolism
Czasopismo naukowe
Tytuł:
IFI16 promotes the progression of clear cell renal cell carcinoma through the IL6/PI3K/AKT axis.
Autorzy:
Lu K; Department of Urology, The First Affiliated Hospital of Soochow University, Suzhou, 215000, Jiangsu, China.; Department of Urology, Affiliated Changshu Hospital of Nantong University, Changshu, 215500, Jiangsu, China.
Zhao Y; Department of Urology, Xuzhou Cancer Hospital, Affiliated Hospital of Jiangsu University, Xuzhou, 221000, Jiangsu, China.
Li Y; Department of Urology, The First Affiliated Hospital of Soochow University, Suzhou, 215000, Jiangsu, China.
Fu Z; Department of Urology, Affiliated Changshu Hospital of Nantong University, Changshu, 215500, Jiangsu, China.
Chen Y; Department of Urology, Affiliated Changshu Hospital of Nantong University, Changshu, 215500, Jiangsu, China. .
Kong Y; Department of Urology, The First Affiliated Hospital of Soochow University, Suzhou, 215000, Jiangsu, China. .
Li G; Department of Urology, The First Affiliated Hospital of Soochow University, Suzhou, 215000, Jiangsu, China. .
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Źródło:
Journal of translational medicine [J Transl Med] 2024 Jun 03; Vol. 22 (1), pp. 533. Date of Electronic Publication: 2024 Jun 03.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Renal Cell*/genetics
Carcinoma, Renal Cell*/pathology
Carcinoma, Renal Cell*/metabolism
Proto-Oncogene Proteins c-akt*/metabolism
Phosphatidylinositol 3-Kinases*/metabolism
Kidney Neoplasms*/pathology
Kidney Neoplasms*/genetics
Kidney Neoplasms*/metabolism
Signal Transduction*
Interleukin-6*/metabolism
Cell Proliferation*
Phosphoproteins*/metabolism
Phosphoproteins*/genetics
Nuclear Proteins*/metabolism
Nuclear Proteins*/genetics
Disease Progression*
Cell Movement*/genetics
Epithelial-Mesenchymal Transition*/genetics
Humans ; Cell Line, Tumor ; Animals ; Gene Expression Regulation, Neoplastic ; Mice, Nude ; Neoplasm Invasiveness ; Male ; Female ; Prognosis
Czasopismo naukowe
Tytuł:
The Interleukin-6 gene variants may protect against SARS-CoV-2 infection and the severity of COVID-19: a case-control study in a Moroccan population.
Autorzy:
Noureddine R; Virology Unit, Viral Hepatitis Laboratory, Institut Pasteur du Maroc, 1 Place Louis Pasteur, Casablanca, 20360, Maroc.; Laboratory of Genetics and Molecular Pathology, Medical School, University Hassan II, Casablanca, Maroc.; Laboratoire Morizgo d'analyses médicales, Casablanca, Maroc.
Baba H; Virology Unit, Viral Hepatitis Laboratory, Institut Pasteur du Maroc, 1 Place Louis Pasteur, Casablanca, 20360, Maroc.
Aqillouch S; Virology Unit, Viral Hepatitis Laboratory, Institut Pasteur du Maroc, 1 Place Louis Pasteur, Casablanca, 20360, Maroc.
Abounouh K; Virology Unit, Viral Hepatitis Laboratory, Institut Pasteur du Maroc, 1 Place Louis Pasteur, Casablanca, 20360, Maroc.
Laazaazia O; Virology Unit, Viral Hepatitis Laboratory, Institut Pasteur du Maroc, 1 Place Louis Pasteur, Casablanca, 20360, Maroc.
Elmessaoudi-Idrissi M; Virology Unit, Viral Hepatitis Laboratory, Institut Pasteur du Maroc, 1 Place Louis Pasteur, Casablanca, 20360, Maroc.
Bahmani FZ; Laboratoire Morizgo d'analyses médicales, Casablanca, Maroc.
Tanouti IA; Virology Unit, Viral Hepatitis Laboratory, Institut Pasteur du Maroc, 1 Place Louis Pasteur, Casablanca, 20360, Maroc.
Ouladlahsen A; Service des maladies Infectieuses, CHU Ibn Rochd, Casablanca, Maroc.
Sarih M; Service de Parasitologie et des Maladies Vectorielles, Institut Pasteur du Maroc, Casablanca, Morocco.
Dehbi H; Laboratory of Genetics and Molecular Pathology, Medical School, University Hassan II, Casablanca, Maroc.
Ezzikouri S; Virology Unit, Viral Hepatitis Laboratory, Institut Pasteur du Maroc, 1 Place Louis Pasteur, Casablanca, 20360, Maroc. .
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Źródło:
BMC medical genomics [BMC Med Genomics] 2024 May 23; Vol. 17 (1), pp. 139. Date of Electronic Publication: 2024 May 23.
Typ publikacji:
Journal Article
MeSH Terms:
COVID-19*/genetics
COVID-19*/virology
Interleukin-6*/genetics
Polymorphism, Single Nucleotide*
SARS-CoV-2*
Genetic Predisposition to Disease*
Severity of Illness Index*
Humans ; Female ; Male ; Case-Control Studies ; Morocco ; Middle Aged ; Adult ; Promoter Regions, Genetic ; Aged ; Gene Frequency ; Haplotypes
Czasopismo naukowe
Tytuł:
Mesothelioma-Associated Fibroblasts Modulate the Response of Mesothelioma Patient-Derived Organoids to Chemotherapy via Interleukin-6.
Autorzy:
Cioce M; Laboratory of Molecular Medicine and Biotechnology, Department of Medicine, University of Campus-Biomedico of Rome, 00128 Rome, Italy.; Institute of Translational Pharmacology, National Research Council of Italy (CNR), 00133 Rome, Italy.
Gatti V; Laboratory of Molecular Medicine and Biotechnology, Department of Medicine, University of Campus-Biomedico of Rome, 00128 Rome, Italy.
Napolitano F; Department of Translational Medical Sciences, University of Naples Federico II, 81025 Naples, Italy.
Giorgiano NM; Thoracic Surgery Unity, Department of Translational Medical Sciences, University of Campania Luigi Vanvitelli, 80138 Naples, Italy.
Marra A; Laboratory of Molecular Medicine and Biotechnology, Department of Medicine, University of Campus-Biomedico of Rome, 00128 Rome, Italy.; Institute of Translational Pharmacology, National Research Council of Italy (CNR), 00133 Rome, Italy.
Portella G; Department of Translational Medical Sciences, University of Naples Federico II, 81025 Naples, Italy.
Fiorelli A; Thoracic Surgery Unity, Department of Translational Medical Sciences, University of Campania Luigi Vanvitelli, 80138 Naples, Italy.
Pentimalli F; Department of Medicine and Surgery, LUM University, 70010 Casamassima, Italy.
Fazio VM; Laboratory of Molecular Medicine and Biotechnology, Department of Medicine, University of Campus-Biomedico of Rome, 00128 Rome, Italy.; Institute of Translational Pharmacology, National Research Council of Italy (CNR), 00133 Rome, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 May 14; Vol. 25 (10). Date of Electronic Publication: 2024 May 14.
Typ publikacji:
Journal Article
MeSH Terms:
Organoids*/metabolism
Organoids*/drug effects
Organoids*/pathology
Interleukin-6*/metabolism
Cisplatin*/pharmacology
Pemetrexed*/pharmacology
Mesothelioma, Malignant*/drug therapy
Mesothelioma, Malignant*/pathology
Mesothelioma, Malignant*/metabolism
Cancer-Associated Fibroblasts*/metabolism
Cancer-Associated Fibroblasts*/drug effects
Cancer-Associated Fibroblasts*/pathology
Mesothelioma*/pathology
Mesothelioma*/drug therapy
Mesothelioma*/metabolism
Humans ; Tumor Microenvironment/drug effects ; Male ; Female ; Fibroblasts/metabolism ; Fibroblasts/drug effects ; Fibroblasts/pathology ; Middle Aged ; Aged ; Antineoplastic Agents/pharmacology ; Neoplastic Stem Cells/metabolism ; Neoplastic Stem Cells/drug effects ; Neoplastic Stem Cells/pathology ; Lung Neoplasms/drug therapy ; Lung Neoplasms/metabolism ; Lung Neoplasms/pathology
Czasopismo naukowe
Tytuł:
An On-Treatment Decreased Trend of Serum IL-6 and IL-8 as Predictive Markers Quickly Reflects Short-Term Efficacy of PD-1 Blockade Immunochemotherapy in Patients with Advanced Gastric Cancer.
Autorzy:
Liu J; Department of Nuclear Medicine, The Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu 212001, China.
Mao Y; Department of Ultrasound Medicine, The Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu 212001, China.
Mao C; Department of Nuclear Medicine, The Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu 212001, China.
Wang D; Department of Oncology, Institute of Digestive Diseases, The Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu 212001, China.
Dong L; Department of Nuclear Medicine, The Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu 212001, China.
Zhu W; School of Medicine, Jiangsu University, Zhenjiang, Jiangsu 212013, China.
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Źródło:
Journal of immunology research [J Immunol Res] 2024 May 14; Vol. 2024, pp. 3604935. Date of Electronic Publication: 2024 May 14 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Stomach Neoplasms*/drug therapy
Stomach Neoplasms*/diagnosis
Stomach Neoplasms*/therapy
Stomach Neoplasms*/immunology
Biomarkers, Tumor*/blood
Immune Checkpoint Inhibitors*/therapeutic use
Interleukin-6*/blood
Programmed Cell Death 1 Receptor*/antagonists & inhibitors
Interleukin-8*/blood
Humans ; Female ; Male ; Middle Aged ; Aged ; Retrospective Studies ; Treatment Outcome ; Adult ; Prognosis ; Immunotherapy/methods ; Neoplasm Staging ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use
Czasopismo naukowe

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