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Tytuł :
Interleukin-6: A Masterplayer in the Cytokine Network.
Autorzy :
Uciechowski P; Institute of Immunology, Medical Faculty, RWTH, Aachen, Germany.
Dempke WCM; University of Munich, Medical Faculty, Munich, Germany, .
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Źródło :
Oncology [Oncology] 2020; Vol. 98 (3), pp. 131-137. Date of Electronic Publication: 2020 Jan 20.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Signal Transduction*
Inflammation/*metabolism
Inflammation Mediators/*metabolism
Interleukin-6/*metabolism
Anti-Inflammatory Agents/therapeutic use ; Humans ; Inflammation/drug therapy ; Inflammation/enzymology ; Inflammation Mediators/antagonists & inhibitors ; Interleukin-6/antagonists & inhibitors ; Janus Kinase Inhibitors/therapeutic use ; Janus Kinases/antagonists & inhibitors ; Janus Kinases/metabolism ; Molecular Targeted Therapy ; Receptors, Interleukin-6/antagonists & inhibitors ; Receptors, Interleukin-6/metabolism ; STAT Transcription Factors/antagonists & inhibitors ; STAT Transcription Factors/metabolism
Czasopismo naukowe
Tytuł :
A benefit and the prospects of IL-6 inhibitors in idiopathic multicentric Castleman's disease.
Autorzy :
Koga T; a Unit of Advanced Preventive Medical Sciences , Nagasaki University Graduate School of Biomedical Sciences , Nagasaki , Japan.; b Center for Bioinformatics and Molecular Medicine , Nagasaki University Graduate School of Biomedical Sciences , Nagasaki , Japan.
Sumiyoshi R; a Unit of Advanced Preventive Medical Sciences , Nagasaki University Graduate School of Biomedical Sciences , Nagasaki , Japan.
Kawakami A; a Unit of Advanced Preventive Medical Sciences , Nagasaki University Graduate School of Biomedical Sciences , Nagasaki , Japan.
Yoshizaki K; c Department of Biomolecular Science and Regulation , The Institute of Scientific and Industrial Research, Osaka University , Osaka , Japan.
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Źródło :
Modern rheumatology [Mod Rheumatol] 2019 Mar; Vol. 29 (2), pp. 302-305. Date of Electronic Publication: 2019 Jan 14.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Castleman Disease*/diagnosis
Castleman Disease*/immunology
Castleman Disease*/therapy
Interleukin-6*/antagonists & inhibitors
Interleukin-6*/blood
Antibodies, Monoclonal, Humanized/*pharmacology
Glucocorticoids/*pharmacology
Antibodies/blood ; Herpesvirus 8, Human/immunology ; Humans ; Immunologic Factors/pharmacology ; Japan ; Prognosis ; Receptors, Interleukin-6/immunology ; Treatment Outcome
SCR Disease Name :
Multi-centric Castleman's Disease
Czasopismo naukowe
Tytuł :
Inhibition of interleukin-6 on matrix protein production by glomerular mesangial cells and the pathway involved.
Autorzy :
Chaudhari S; Department of Physiology and Anatomy, University of North Texas Health Science Center, Fort Worth, Texas.
Yazdizadeh Shotorbani P; Department of Physiology and Anatomy, University of North Texas Health Science Center, Fort Worth, Texas.
Tao Y; Department of Physiology and Anatomy, University of North Texas Health Science Center, Fort Worth, Texas.
Davis ME; Chemical Engineering, California Institute of Technology, Pasadena, California.
Mallet RT; Department of Physiology and Anatomy, University of North Texas Health Science Center, Fort Worth, Texas.
Ma R; Department of Physiology and Anatomy, University of North Texas Health Science Center, Fort Worth, Texas.
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Źródło :
American journal of physiology. Renal physiology [Am J Physiol Renal Physiol] 2020 Jun 01; Vol. 318 (6), pp. F1478-F1488. Date of Electronic Publication: 2020 May 11.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Extracellular Matrix Proteins/*metabolism
Interleukin-6/*metabolism
Mesangial Cells/*metabolism
Receptors, Interleukin-6/*metabolism
Animals ; Cells, Cultured ; Down-Regulation ; Extracellular Matrix Proteins/genetics ; Glucagon-Like Peptide-1 Receptor/genetics ; Glucagon-Like Peptide-1 Receptor/metabolism ; Humans ; Interleukin-6/genetics ; Male ; Mice, Inbred C57BL ; NF-kappa B/genetics ; NF-kappa B/metabolism ; ORAI1 Protein/genetics ; ORAI1 Protein/metabolism ; Receptors, Interleukin-6/genetics ; Signal Transduction
Czasopismo naukowe
Tytuł :
EBV Rta-induced IL-6 Promotes Migration of Bystander Tumor Cells Through IL-6R/JAK/STAT3 Pathway In Vitro .
Autorzy :
Tung KL; Department of Dental Technology, Shu-Zen Junior College of Medicine and Management, Kaohsiung, Taiwan, R.O.C.
Wu YT; Department of Pathology, Golden Hospital, Pingtung, Taiwan, R.O.C.
Liu C; Department of Dental Technology, Shu-Zen Junior College of Medicine and Management, Kaohsiung, Taiwan, R.O.C.; Department of Health and Beauty, Shu-Zen Junior College of Medicine and Management, Kaohsiung, Taiwan, R.O.C.
Lin SC; Department of Dental Technology, Shu-Zen Junior College of Medicine and Management, Kaohsiung, Taiwan, R.O.C.
Wu CH; Department of Dental Technology, Shu-Zen Junior College of Medicine and Management, Kaohsiung, Taiwan, R.O.C.
Wu SY; Department of Pathology, Golden Hospital, Pingtung, Taiwan, R.O.C.
Chang Y; National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Tainan, Taiwan, R.O.C.
Lan YY; Department of Physical Therapy, Shu-Zen Junior College of Medicine and Management, Kaohsiung, Taiwan, R.O.C. .
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Źródło :
Anticancer research [Anticancer Res] 2020 Jun; Vol. 40 (6), pp. 3255-3264.
Typ publikacji :
Journal Article
MeSH Terms :
Immediate-Early Proteins/*metabolism
Interleukin-6/*metabolism
Janus Kinases/*metabolism
Neoplasms/*metabolism
Receptors, Interleukin-6/*metabolism
STAT3 Transcription Factor/*metabolism
Trans-Activators/*metabolism
Breast Neoplasms/genetics ; Breast Neoplasms/metabolism ; Breast Neoplasms/pathology ; Breast Neoplasms/virology ; Cell Line, Tumor ; Cell Movement/physiology ; Humans ; Immediate-Early Proteins/genetics ; Interleukin-6/biosynthesis ; Interleukin-6/genetics ; MAP Kinase Signaling System ; MCF-7 Cells ; Nasopharyngeal Carcinoma/genetics ; Nasopharyngeal Carcinoma/metabolism ; Nasopharyngeal Carcinoma/pathology ; Nasopharyngeal Carcinoma/virology ; Nasopharyngeal Neoplasms/genetics ; Nasopharyngeal Neoplasms/metabolism ; Nasopharyngeal Neoplasms/pathology ; Nasopharyngeal Neoplasms/virology ; Neoplasms/genetics ; Neoplasms/pathology ; Neoplasms/virology ; Signal Transduction ; Stomach Neoplasms/genetics ; Stomach Neoplasms/metabolism ; Stomach Neoplasms/pathology ; Stomach Neoplasms/virology ; Trans-Activators/genetics ; Transcription Factor AP-1/metabolism ; Transfection ; Up-Regulation
Czasopismo naukowe
Tytuł :
IL-6-induced CD39 expression on tumor-infiltrating NK cells predicts poor prognosis in esophageal squamous cell carcinoma.
Autorzy :
Zheng Y; Biotherapy Center, the First Affiliated Hospital of Zhengzhou University, 1 Jianshe East Road, Zhengzhou, 450052, Henan, People's Republic of China.
Li Y; Biotherapy Center, the First Affiliated Hospital of Zhengzhou University, 1 Jianshe East Road, Zhengzhou, 450052, Henan, People's Republic of China.
Tang B; Biotherapy Center, the First Affiliated Hospital of Zhengzhou University, 1 Jianshe East Road, Zhengzhou, 450052, Henan, People's Republic of China.
Zhao Q; Biotherapy Center, the First Affiliated Hospital of Zhengzhou University, 1 Jianshe East Road, Zhengzhou, 450052, Henan, People's Republic of China.
Wang D; Biotherapy Center, the First Affiliated Hospital of Zhengzhou University, 1 Jianshe East Road, Zhengzhou, 450052, Henan, People's Republic of China.
Liu Y; Biotherapy Center, the First Affiliated Hospital of Zhengzhou University, 1 Jianshe East Road, Zhengzhou, 450052, Henan, People's Republic of China.
Guo M; Biotherapy Center, the First Affiliated Hospital of Zhengzhou University, 1 Jianshe East Road, Zhengzhou, 450052, Henan, People's Republic of China.
Zhao S; Department of Thoracic Surgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, People's Republic of China.
Qi Y; Department of Thoracic Surgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, People's Republic of China.
Zhang Y; Biotherapy Center, the First Affiliated Hospital of Zhengzhou University, 1 Jianshe East Road, Zhengzhou, 450052, Henan, People's Republic of China. .
Huang L; Biotherapy Center, the First Affiliated Hospital of Zhengzhou University, 1 Jianshe East Road, Zhengzhou, 450052, Henan, People's Republic of China. .
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Źródło :
Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2020 Nov; Vol. 69 (11), pp. 2371-2380. Date of Electronic Publication: 2020 Jun 10.
Typ publikacji :
Journal Article
MeSH Terms :
Apyrase/*immunology
Esophageal Neoplasms/*immunology
Esophageal Squamous Cell Carcinoma/*immunology
Interleukin-6/*immunology
Killer Cells, Natural/*immunology
Apyrase/biosynthesis ; Female ; Humans ; Interleukin-6/metabolism ; Killer Cells, Natural/metabolism ; Lymphocytes, Tumor-Infiltrating/immunology ; Lymphocytes, Tumor-Infiltrating/metabolism ; Male ; Prognosis ; Tumor Escape/immunology ; Tumor Microenvironment/immunology
Czasopismo naukowe
Tytuł :
The role of Interleukin 6 inhibitors in therapy of severe COVID-19.
Autorzy :
Nasonov E; V.A. Nasonova Research Institute of Rheumatology, Moscow, Russia; I.M. Sechenov First Moscow State Medical University, MOH, Moscow, Russia; Kashirskoye roadway, 34А, 1115522, Moscow, Russia; Trubetskaya str, 8, bdg. 2, 2119991, Moscow, Russia. Electronic address: .
Samsonov M; RPharm JSC, Leninsky prospect 111, 11942, Moscow, Russia. Electronic address: .
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2020 Nov; Vol. 131, pp. 110698. Date of Electronic Publication: 2020 Aug 28.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Coronavirus Infections/*drug therapy
Interleukin-6/*antagonists & inhibitors
Pneumonia, Viral/*drug therapy
Anti-Inflammatory Agents/pharmacology ; Betacoronavirus/immunology ; Betacoronavirus/isolation & purification ; Coronavirus Infections/complications ; Coronavirus Infections/immunology ; Cytokine Release Syndrome/drug therapy ; Cytokine Release Syndrome/immunology ; Cytokine Release Syndrome/virology ; Cytokines/immunology ; Humans ; Interleukin-6/immunology ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/immunology ; Prognosis ; Severity of Illness Index
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Upregulation of TNF-α and IL-6 induces preterm premature rupture of membranes by activation of ADAMTS-9 in embryonic membrane cells.
Autorzy :
Li W; Tianjin Key Laboratory of Human Development and Reproductive Regulation, China; Maternity Hospital of Nankai University, China.
Zhao X; Tianjin Central Hospital of Gynecology Obstetrics, China.
Li S; Tianjin Key Laboratory of Human Development and Reproductive Regulation, China; Tianjin Central Hospital of Gynecology Obstetrics, China.
Chen X; Tianjin Key Laboratory of Human Development and Reproductive Regulation, China; Tianjin Central Hospital of Gynecology Obstetrics, China.
Cui H; Tianjin Central Hospital of Gynecology Obstetrics, China.
Chang Y; Tianjin Key Laboratory of Human Development and Reproductive Regulation, China; Tianjin Central Hospital of Gynecology Obstetrics, China. Electronic address: .
Zhang R; Guangdong Province Key Laboratory for Biotechnology Drug Candidates, School of Life Sciences and Biopharmaceutics, China; Guangdong Pharmaceutical University, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 Nov 01; Vol. 260, pp. 118237. Date of Electronic Publication: 2020 Aug 08.
Typ publikacji :
Journal Article
MeSH Terms :
ADAMTS9 Protein/*physiology
Fetal Membranes, Premature Rupture/*physiopathology
Interleukin-6/*physiology
Tumor Necrosis Factor-alpha/*physiology
ADAMTS9 Protein/genetics ; Adult ; Animals ; Apoptosis ; Cell Line ; Female ; Gene Knockdown Techniques ; Gestational Age ; Humans ; Inflammation/physiopathology ; Interleukin-6/genetics ; Macrophages/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Placenta/chemistry ; Pregnancy ; Premature Birth/physiopathology ; RNA, Messenger/analysis ; THP-1 Cells ; Tumor Necrosis Factor-alpha/genetics ; Up-Regulation
SCR Disease Name :
Preterm Premature Rupture of the Membranes
Czasopismo naukowe
Tytuł :
Expression profiles and function of IL6 in polymorphonuclear myeloid-derived suppressor cells.
Autorzy :
Ibrahim ML; Department of Biochemistry and Molecular Biology, Medical College of Georgia, 1410 Laney Walker Blvd, Augusta, GA, 30912, USA.; Georgia Cancer Center, Medical College of Georgia, Augusta, GA, 30912, USA.; Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, Cairo University, Cairo, Egypt.
Lu C; Department of Biochemistry and Molecular Biology, Medical College of Georgia, 1410 Laney Walker Blvd, Augusta, GA, 30912, USA.; Georgia Cancer Center, Medical College of Georgia, Augusta, GA, 30912, USA.; Charlie Norwood VA Medical Center, Augusta, GA, 30904, USA.
Klement JD; Department of Biochemistry and Molecular Biology, Medical College of Georgia, 1410 Laney Walker Blvd, Augusta, GA, 30912, USA.; Georgia Cancer Center, Medical College of Georgia, Augusta, GA, 30912, USA.; Charlie Norwood VA Medical Center, Augusta, GA, 30904, USA.
Redd PS; Department of Biochemistry and Molecular Biology, Medical College of Georgia, 1410 Laney Walker Blvd, Augusta, GA, 30912, USA.; Georgia Cancer Center, Medical College of Georgia, Augusta, GA, 30912, USA.; Charlie Norwood VA Medical Center, Augusta, GA, 30904, USA.
Yang D; Department of Biochemistry and Molecular Biology, Medical College of Georgia, 1410 Laney Walker Blvd, Augusta, GA, 30912, USA.; Georgia Cancer Center, Medical College of Georgia, Augusta, GA, 30912, USA.; Charlie Norwood VA Medical Center, Augusta, GA, 30904, USA.
Smith AD; Department of Biochemistry and Molecular Biology, Medical College of Georgia, 1410 Laney Walker Blvd, Augusta, GA, 30912, USA.; Georgia Cancer Center, Medical College of Georgia, Augusta, GA, 30912, USA.; Charlie Norwood VA Medical Center, Augusta, GA, 30904, USA.
Liu K; Department of Biochemistry and Molecular Biology, Medical College of Georgia, 1410 Laney Walker Blvd, Augusta, GA, 30912, USA. .; Georgia Cancer Center, Medical College of Georgia, Augusta, GA, 30912, USA. .; Charlie Norwood VA Medical Center, Augusta, GA, 30904, USA. .
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Źródło :
Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2020 Nov; Vol. 69 (11), pp. 2233-2245. Date of Electronic Publication: 2020 Jun 01.
Typ publikacji :
Journal Article
MeSH Terms :
Adenocarcinoma/*immunology
Colorectal Neoplasms/*immunology
Interleukin-6/*immunology
Myeloid-Derived Suppressor Cells/*immunology
Tumor Microenvironment/*immunology
Adenocarcinoma/pathology ; Animals ; Colorectal Neoplasms/pathology ; Gene Expression Regulation, Neoplastic/physiology ; Humans ; Interleukin-6/metabolism ; Mice ; Mice, Inbred BALB C ; Myeloid-Derived Suppressor Cells/metabolism ; Signal Transduction/immunology ; Transcriptome
Czasopismo naukowe
Tytuł :
Interleukin-6: Molecule in the Intersection of Cancer, Ageing and COVID-19.
Autorzy :
Brábek J; Department of Cell Biology, Faculty of Science, Charles University, 120 00 Prague 2, Czech Republic.; BIOCEV, Faculty of Science, Charles University, 252 50 Vestec, Czech Republic.; Centre for Tumour Ecology, First Faculty of Medicine, Charles University, 120 00 Prague 2, Czech Republic.
Jakubek M; Centre for Tumour Ecology, First Faculty of Medicine, Charles University, 120 00 Prague 2, Czech Republic.; Department of Paediatrics and Adolescent Medicine, First Faculty of Medicine, Charles University and General University Hospital, 120 00 Prague, Czech Republic.; BIOCEV, First Faculty of Medicine, Charles University, 252 50 Vestec, Czech Republic.; Department of Analytical Chemistry, University of Chemistry and Technology Prague, 166 28 Praha 6, Czech Republic.
Vellieux F; Centre for Tumour Ecology, First Faculty of Medicine, Charles University, 120 00 Prague 2, Czech Republic.; BIOCEV, First Faculty of Medicine, Charles University, 252 50 Vestec, Czech Republic.
Novotný J; Centre for Tumour Ecology, First Faculty of Medicine, Charles University, 120 00 Prague 2, Czech Republic.; Laboratory of Genomics and Bioinformatics, Institute of Molecular Genetics, Czech Academy of Sciences, 140 00 Prague 4, Czech Republic.
Kolář M; Centre for Tumour Ecology, First Faculty of Medicine, Charles University, 120 00 Prague 2, Czech Republic.; Laboratory of Genomics and Bioinformatics, Institute of Molecular Genetics, Czech Academy of Sciences, 140 00 Prague 4, Czech Republic.
Lacina L; Centre for Tumour Ecology, First Faculty of Medicine, Charles University, 120 00 Prague 2, Czech Republic.; BIOCEV, First Faculty of Medicine, Charles University, 252 50 Vestec, Czech Republic.; Institute of Anatomy, Fist Faculty of Medicine, Charles University, 120 00 Prague 2, Czech Republic.; Department of Dermatovenereology, First Faculty of Medicine, Charles University and General University Hospital, 120 00 Prague 2, Czech Republic.
Szabo P; Institute of Anatomy, Fist Faculty of Medicine, Charles University, 120 00 Prague 2, Czech Republic.
Strnadová K; Centre for Tumour Ecology, First Faculty of Medicine, Charles University, 120 00 Prague 2, Czech Republic.; BIOCEV, First Faculty of Medicine, Charles University, 252 50 Vestec, Czech Republic.; Institute of Anatomy, Fist Faculty of Medicine, Charles University, 120 00 Prague 2, Czech Republic.
Rösel D; Department of Cell Biology, Faculty of Science, Charles University, 120 00 Prague 2, Czech Republic.; BIOCEV, Faculty of Science, Charles University, 252 50 Vestec, Czech Republic.; Centre for Tumour Ecology, First Faculty of Medicine, Charles University, 120 00 Prague 2, Czech Republic.
Dvořánková B; Centre for Tumour Ecology, First Faculty of Medicine, Charles University, 120 00 Prague 2, Czech Republic.; BIOCEV, First Faculty of Medicine, Charles University, 252 50 Vestec, Czech Republic.; Institute of Anatomy, Fist Faculty of Medicine, Charles University, 120 00 Prague 2, Czech Republic.
Smetana K Jr; Centre for Tumour Ecology, First Faculty of Medicine, Charles University, 120 00 Prague 2, Czech Republic.; BIOCEV, First Faculty of Medicine, Charles University, 252 50 Vestec, Czech Republic.; Institute of Anatomy, Fist Faculty of Medicine, Charles University, 120 00 Prague 2, Czech Republic.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Oct 26; Vol. 21 (21). Date of Electronic Publication: 2020 Oct 26.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Aging/*metabolism
Coronavirus Infections/*metabolism
Interleukin-6/*metabolism
Neoplasms/*metabolism
Pneumonia, Viral/*metabolism
Aging/pathology ; Animals ; Coronavirus Infections/pathology ; Humans ; Interleukin-6/genetics ; Neoplasms/pathology ; Pandemics ; Pneumonia, Viral/pathology ; Signal Transduction
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
The Inhibition of NLRP3 Inflammasome and IL-6 Production by Hibiscus noldeae Baker f. Derived Constituents Provides a Link to Its Anti-Inflammatory Therapeutic Potentials.
Autorzy :
Tomani JCD; School of Medicine and Pharmacy, College of Medicine and Health Sciences, University of Rwanda, P.O. Box 3286 Kigali, Rwanda.; Department of Molecular Biology, Institute for Molecular Biology and Medicine, Université Libre de Bruxelles, 6041 Gosselies, Belgium.
Kagisha V; School of Medicine and Pharmacy, College of Medicine and Health Sciences, University of Rwanda, P.O. Box 3286 Kigali, Rwanda.; Laboratory of Pharmacognosy, Centre for Interdisciplinary Research on Medicines (CIRM), University of Liège, B36, 4000 Liège, Belgium.
Tchinda AT; Laboratory of Phytochemistry, Centre for Research on Medicinal Plants and Traditional Medicine, Institute of Medical Research and Medicinal Plants Studies, Yaoundé P.O. Box 6163, Cameroon.
Jansen O; Laboratory of Pharmacognosy, Centre for Interdisciplinary Research on Medicines (CIRM), University of Liège, B36, 4000 Liège, Belgium.
Ledoux A; Laboratory of Pharmacognosy, Centre for Interdisciplinary Research on Medicines (CIRM), University of Liège, B36, 4000 Liège, Belgium.
Vanhamme L; Department of Molecular Biology, Institute for Molecular Biology and Medicine, Université Libre de Bruxelles, 6041 Gosselies, Belgium.
Frederich M; Laboratory of Pharmacognosy, Centre for Interdisciplinary Research on Medicines (CIRM), University of Liège, B36, 4000 Liège, Belgium.
Muganga R; School of Medicine and Pharmacy, College of Medicine and Health Sciences, University of Rwanda, P.O. Box 3286 Kigali, Rwanda.
Souopgui J; Department of Molecular Biology, Institute for Molecular Biology and Medicine, Université Libre de Bruxelles, 6041 Gosselies, Belgium.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2020 Oct 14; Vol. 25 (20). Date of Electronic Publication: 2020 Oct 14.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Inflammatory Agents/*pharmacology
Hibiscus/*chemistry
Inflammasomes/*drug effects
Inflammation/*drug therapy
Interleukin-6/*antagonists & inhibitors
NLR Family, Pyrin Domain-Containing 3 Protein/*antagonists & inhibitors
Plant Extracts/*pharmacology
Animals ; Inflammasomes/immunology ; Inflammasomes/metabolism ; Inflammation/immunology ; Inflammation/metabolism ; Inflammation/pathology ; Interleukin-6/metabolism ; Macrophages/drug effects ; Macrophages/immunology ; Macrophages/metabolism ; Mice ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; RAW 264.7 Cells
Czasopismo naukowe
Tytuł :
Interleukin 6 levels after tocilizumab administration in transplant recipients with COVID-19.
Autorzy :
Gade AR; Internal Medicine Residency Program, Department of Medicine, Medical City Fort Worth, Fort Worth, Texas, USA.
Alavala H; Division of Transplant Nephrology, Tarrant Nephrology Associates/Premier Physicians Group Health, Fort Worth, Texas, USA.
Allam SR; Division of Transplant Nephrology, Tarrant Nephrology Associates/Premier Physicians Group Health, Fort Worth, Texas, USA. Electronic address: .
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Źródło :
Kidney international [Kidney Int] 2020 Oct; Vol. 98 (4), pp. 1054. Date of Electronic Publication: 2020 Jul 08.
Typ publikacji :
Letter; Comment
MeSH Terms :
Coronavirus Infections*
Interleukin-6*
Kidney Transplantation*
Pandemics*
Pneumonia, Viral*
Antibodies, Monoclonal, Humanized ; Betacoronavirus ; Cytokine Release Syndrome ; Humans ; Transplant Recipients
SCR Disease Name :
COVID-19
Opinia redakcyjna
Tytuł :
Sepsis-associated severe interleukin-6 storm in critical coronavirus disease 2019.
Autorzy :
Huang L; Biotherapy Center, The First Affiliated Hospital, Zhengzhou University, No. 1 Jianshe East Road, 450052, Zhengzhou, Henan, China. .
Zhao X; Biotherapy Center, The First Affiliated Hospital, Zhengzhou University, No. 1 Jianshe East Road, 450052, Zhengzhou, Henan, China.
Qi Y; Department of Thoracic Surgery, The First Affiliated Hospital, Zhengzhou University, No. 1 Jianshe East Road, 450052, Zhengzhou, Henan, China.
Li H; Biotherapy Center, The First Affiliated Hospital, Zhengzhou University, No. 1 Jianshe East Road, 450052, Zhengzhou, Henan, China.
Ye G; Department of Thoracic Surgery, The First Affiliated Hospital, Zhengzhou University, No. 1 Jianshe East Road, 450052, Zhengzhou, Henan, China.
Liu Y; Department of Thoracic Surgery, The First Affiliated Hospital, Zhengzhou University, No. 1 Jianshe East Road, 450052, Zhengzhou, Henan, China.
Zhang Y; Biotherapy Center, The First Affiliated Hospital, Zhengzhou University, No. 1 Jianshe East Road, 450052, Zhengzhou, Henan, China. .
Gou J; Department of Clinical Laboratory, The First Affiliated Hospital, Zhengzhou University, No. 1 Jianshe East Road, 450052, Zhengzhou, Henan, China. .
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Źródło :
Cellular & molecular immunology [Cell Mol Immunol] 2020 Oct; Vol. 17 (10), pp. 1092-1094. Date of Electronic Publication: 2020 Sep 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Betacoronavirus/*pathogenicity
Coronavirus Infections/*complications
Cytokine Release Syndrome/*complications
Interleukin-6/*immunology
Lymphopenia/*complications
Pneumonia, Viral/*complications
Sepsis/*complications
Acute Disease ; Betacoronavirus/immunology ; Biomarkers/blood ; Coronavirus Infections/immunology ; Coronavirus Infections/mortality ; Coronavirus Infections/virology ; Critical Illness ; Cytokine Release Syndrome/immunology ; Cytokine Release Syndrome/mortality ; Cytokine Release Syndrome/virology ; Humans ; Interferon-gamma/blood ; Interferon-gamma/immunology ; Interleukin-10/blood ; Interleukin-10/immunology ; Interleukin-2/blood ; Interleukin-2/immunology ; Interleukin-4/blood ; Interleukin-4/immunology ; Interleukin-6/blood ; Lymphopenia/immunology ; Lymphopenia/mortality ; Lymphopenia/virology ; Pandemics ; Pneumonia, Viral/immunology ; Pneumonia, Viral/mortality ; Pneumonia, Viral/virology ; Procalcitonin/blood ; Procalcitonin/immunology ; Sepsis/immunology ; Sepsis/mortality ; Sepsis/virology ; Survival Analysis ; Tumor Necrosis Factor-alpha/blood ; Tumor Necrosis Factor-alpha/immunology
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Impact of interleukin-6 blockade with tocilizumab on SARS-CoV-2 viral kinetics and antibody responses in patients with COVID-19: A prospective cohort study.
Autorzy :
Masiá M; Hospital General Universitario de Elche and Universidad Miguel Hernández, Camí de la Almazara 11, Elche, Alicante 03203, Spain. Electronic address: .
Fernández-González M; Hospital General Universitario de Elche, Camí de la Almazara 11, Elche, Alicante 03203, Spain.
Padilla S; Hospital General Universitario de Elche, Camí de la Almazara 11, Elche, Alicante 03203, Spain.
Ortega P; Hospital General Universitario de Elche, Camí de la Almazara 11, Elche, Alicante 03203, Spain.
García JA; Operational Research Center, Universidad Miguel Hernández, Elche, Alicante, Spain.
Agulló V; Hospital General Universitario de Elche, Camí de la Almazara 11, Elche, Alicante 03203, Spain.
García-Abellán J; Hospital General Universitario de Elche, Camí de la Almazara 11, Elche, Alicante 03203, Spain.
Telenti G; Hospital General Universitario de Elche, Camí de la Almazara 11, Elche, Alicante 03203, Spain.
Guillén L; Hospital General Universitario de Elche, Camí de la Almazara 11, Elche, Alicante 03203, Spain.
Gutiérrez F; Hospital General Universitario de Elche and Universidad Miguel Hernández, Camí de la Almazara 11, Elche, Alicante 03203, Spain. Electronic address: .
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Źródło :
EBioMedicine [EBioMedicine] 2020 Oct; Vol. 60, pp. 102999. Date of Electronic Publication: 2020 Sep 16.
Typ publikacji :
Journal Article
MeSH Terms :
Antibodies, Monoclonal, Humanized/*immunology
Betacoronavirus/*physiology
Coronavirus Infections/*pathology
Interleukin-6/*immunology
Pneumonia, Viral/*pathology
Aged ; Antibodies, Monoclonal, Humanized/therapeutic use ; Antibodies, Viral/blood ; Antibody Formation ; Betacoronavirus/isolation & purification ; Coronavirus Infections/drug therapy ; Coronavirus Infections/virology ; Female ; Humans ; Immunoglobulin G/blood ; Interleukin-6/analysis ; Kinetics ; Male ; Middle Aged ; Pandemics ; Pneumonia, Viral/drug therapy ; Pneumonia, Viral/virology ; Proportional Hazards Models ; Prospective Studies ; RNA, Viral/blood ; Viral Load
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
COVID-19: Clean up on IL-6.
Autorzy :
Hedrick TL; University of North Carolina Medical Center, Chapel Hill, North Carolina and.
Murray BP; University of North Carolina Medical Center, Chapel Hill, North Carolina and.
Hagan RS; University of North Carolina, Chapel Hill, North Carolina.
Mock JR; University of North Carolina, Chapel Hill, North Carolina.
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Źródło :
American journal of respiratory cell and molecular biology [Am J Respir Cell Mol Biol] 2020 Oct; Vol. 63 (4), pp. 541-543.
Typ publikacji :
Letter; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Betacoronavirus/*drug effects
Coronavirus Infections/*drug therapy
Interleukin-6/*antagonists & inhibitors
Pneumonia, Viral/*drug therapy
Betacoronavirus/pathogenicity ; Humans ; Interleukin-6/metabolism ; Pandemics
SCR Disease Name :
COVID-19
Raport
Tytuł :
Glucose transporter 4 mediates LPS-induced IL-6 production in osteoblasts under high glucose conditions.
Autorzy :
Kato S; Division of Applied Oral Sciences, Nihon University Graduate School of Dentistry.
Tanabe N; Department of Biochemistry, Nihon University School of Dentistry.; Division of Functional Morphology, Dental Research Center, Nihon University School of Dentistry.
Nagao M; Department of Physiology and Pharmacology, Schulich School of Medicine & Dentistry, and Bone and Joint Institute, Western University.
Sekino J; Department of Dysphagia Rehabilitation, Nihon University School of Dentistry.
Tomita K; Division of Applied Oral Sciences, Nihon University Graduate School of Dentistry.
Sakai M; Division of Applied Oral Sciences, Nihon University Graduate School of Dentistry.
Abe K; Division of Functional Morphology, Dental Research Center, Nihon University School of Dentistry.; Department of Dysphagia Rehabilitation, Nihon University School of Dentistry.
Suzuki N; Department of Biochemistry, Nihon University School of Dentistry.; Division of Functional Morphology, Dental Research Center, Nihon University School of Dentistry.
Ueda K; Division of Functional Morphology, Dental Research Center, Nihon University School of Dentistry.; Department of Dysphagia Rehabilitation, Nihon University School of Dentistry.
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Źródło :
Journal of oral science [J Oral Sci] 2020 Sep 26; Vol. 62 (4), pp. 423-426. Date of Electronic Publication: 2020 Aug 31.
Typ publikacji :
Journal Article
MeSH Terms :
Interleukin-6*/metabolism
Lipopolysaccharides*
Glucose Transporter Type 4/*physiology
Glucose ; Glucose Transport Proteins, Facilitative ; Osteoblasts/metabolism
Czasopismo naukowe
Tytuł :
Duplex Shiny app quantification of the sepsis biomarkers C-reactive protein and interleukin-6 in a fast quantum dot labeled lateral flow assay.
Autorzy :
Ruppert C; Medical and Life Sciences Faculty, Furtwangen University, Jakob-Kienzle Str. 17, 78054, Villingen-Schwenningen, Germany.; Institute of Precision Medicine, Furtwangen University, Jakob-Kienzle Str. 17, 78054, Villingen-Schwenningen, Germany.; Department of Pharmaceutical Chemistry, Pharmaceutical Institute, University of Tuebingen, Auf der Morgenstelle 8, 72076, Tübingen, Germany.
Kaiser L; Medical and Life Sciences Faculty, Furtwangen University, Jakob-Kienzle Str. 17, 78054, Villingen-Schwenningen, Germany.; Institute of Precision Medicine, Furtwangen University, Jakob-Kienzle Str. 17, 78054, Villingen-Schwenningen, Germany.; Institute of Pharmaceutical Sciences, University of Freiburg, Albertstraße 25, 79104, Freiburg, Germany.
Jacob LJ; Medical and Life Sciences Faculty, Furtwangen University, Jakob-Kienzle Str. 17, 78054, Villingen-Schwenningen, Germany.; Institute of Precision Medicine, Furtwangen University, Jakob-Kienzle Str. 17, 78054, Villingen-Schwenningen, Germany.
Laufer S; Department of Pharmaceutical Chemistry, Pharmaceutical Institute, University of Tuebingen, Auf der Morgenstelle 8, 72076, Tübingen, Germany.
Kohl M; Medical and Life Sciences Faculty, Furtwangen University, Jakob-Kienzle Str. 17, 78054, Villingen-Schwenningen, Germany. .; Institute of Precision Medicine, Furtwangen University, Jakob-Kienzle Str. 17, 78054, Villingen-Schwenningen, Germany. .
Deigner HP; Medical and Life Sciences Faculty, Furtwangen University, Jakob-Kienzle Str. 17, 78054, Villingen-Schwenningen, Germany. .; Institute of Precision Medicine, Furtwangen University, Jakob-Kienzle Str. 17, 78054, Villingen-Schwenningen, Germany. .; EXIM Department, Fraunhofer Institute IZI, Leipzig, Schillingallee 68, 18057, Rostock, Germany. .; Faculty of Science, Tuebingen University, Auf der Morgenstelle 8, 72076, Tübingen, Germany. .
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Źródło :
Journal of nanobiotechnology [J Nanobiotechnology] 2020 Sep 10; Vol. 18 (1), pp. 130. Date of Electronic Publication: 2020 Sep 10.
Typ publikacji :
Journal Article
MeSH Terms :
Biomarkers/*analysis
C-Reactive Protein/*analysis
Immunoassay/*methods
Interleukin-6/*analysis
Quantum Dots/*chemistry
Sepsis/*diagnosis
Antibodies/immunology ; Betacoronavirus/isolation & purification ; C-Reactive Protein/immunology ; Coronavirus Infections/diagnosis ; Coronavirus Infections/virology ; Humans ; Interleukin-6/immunology ; Limit of Detection ; Pandemics ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/virology ; Point-of-Care Systems ; Sepsis/metabolism ; Software ; Ultraviolet Rays
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Impaired immune cell cytotoxicity in severe COVID-19 is IL-6 dependent.
Autorzy :
Mazzoni A; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Salvati L; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Maggi L; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Capone M; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Vanni A; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Spinicci M; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.; Infectious and Tropical Diseases Unit.
Mencarini J; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.; Infectious and Tropical Diseases Unit.
Caporale R; Flow Cytometry Diagnostic Center and Immunotherapy (CDCI).
Peruzzi B; Flow Cytometry Diagnostic Center and Immunotherapy (CDCI).
Antonelli A; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Trotta M; Infectious and Tropical Diseases Unit.
Zammarchi L; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.; Infectious and Tropical Diseases Unit.
Ciani L; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Gori L; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Lazzeri C; Intensive Care Unit and Regional Extracorporeal Membrane Oxygenation (ECMO) Referral Centre.
Matucci A; Immunoallergology Unit.
Vultaggio A; Immunoallergology Unit.
Rossi O; Immunoallergology Unit.
Almerigogna F; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.; Immunoallergology Unit.
Parronchi P; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.; Immunology and Cell Therapy Unit.
Fontanari P; Cardiac Anesthesia and Intensive Care Unit.
Lavorini F; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.; Pneumology and Intensive Care Unit, and.
Peris A; Intensive Care Unit and Regional Extracorporeal Membrane Oxygenation (ECMO) Referral Centre.
Rossolini GM; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.; Clinical Microbiology and Virology Unit, Careggi University Hospital, Florence, Italy.
Bartoloni A; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.; Infectious and Tropical Diseases Unit.
Romagnani S; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Liotta F; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.; Immunology and Cell Therapy Unit.
Annunziato F; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.; Flow Cytometry Diagnostic Center and Immunotherapy (CDCI).
Cosmi L; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.; Immunology and Cell Therapy Unit.
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Źródło :
The Journal of clinical investigation [J Clin Invest] 2020 Sep 01; Vol. 130 (9), pp. 4694-4703.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Betacoronavirus*
Cytotoxicity, Immunologic*
Coronavirus Infections/*immunology
Interleukin-6/*immunology
Pneumonia, Viral/*immunology
Adult ; Aged ; Aged, 80 and over ; B-Lymphocytes/immunology ; CD4-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/immunology ; Coronavirus Infections/blood ; Coronavirus Infections/epidemiology ; Critical Care ; Cytokines/blood ; Cytokines/immunology ; Female ; Granzymes/blood ; Granzymes/immunology ; Humans ; Interleukin-6/blood ; Killer Cells, Natural/immunology ; Male ; Middle Aged ; Models, Immunological ; Pandemics ; Pneumonia, Viral/blood ; Pneumonia, Viral/epidemiology
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
IL-6 dysregulation originates in dendritic cells and mediates graft-versus-host disease via classical signaling.
Autorzy :
Wilkinson AN; QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.; Faculty of Medicine, University of Queensland, Brisbane, QLD, Australia.
Chang K; QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
Kuns RD; QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
Henden AS; QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.; Faculty of Medicine, University of Queensland, Brisbane, QLD, Australia.; Royal Brisbane and Women's Hospital, Brisbane, QLD, Australia.
Minnie SA; QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.; Faculty of Medicine, University of Queensland, Brisbane, QLD, Australia.
Ensbey KS; QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
Clouston AD; Envoi Specialist Pathologists, Brisbane, QLD, Australia.
Zhang P; QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
Koyama M; QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA.
Hidalgo J; Animal Physiology Unit, Department of Cellular Biology, Physiology and Immunology, Faculty of Biosciences, and.; Institute of Neurosciences, Universitat Autònoma de Barcelona, Bellaterra, Spain.
Rose-John S; Institute of Biochemistry, Christian-Albrechts-Universität zu Kiel, Kiel, Germany; and.
Varelias A; QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.; Faculty of Medicine, University of Queensland, Brisbane, QLD, Australia.
Vuckovic S; QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.; Faculty of Medicine, University of Queensland, Brisbane, QLD, Australia.
Gartlan KH; QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.; Faculty of Medicine, University of Queensland, Brisbane, QLD, Australia.; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA.
Hill GR; QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.; Royal Brisbane and Women's Hospital, Brisbane, QLD, Australia.; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA.; Division of Medical Oncology, University of Washington, Seattle, WA.
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Źródło :
Blood [Blood] 2019 Dec 05; Vol. 134 (23), pp. 2092-2106.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Stem Cell Transplantation*
Dendritic Cells/*immunology
Graft vs Host Disease/*immunology
Interleukin-6/*immunology
Signal Transduction/*immunology
Skin Diseases/*immunology
Allografts ; Animals ; Cell Differentiation/immunology ; Dendritic Cells/pathology ; Gene Deletion ; Graft vs Host Disease/genetics ; Graft vs Host Disease/pathology ; Graft vs Leukemia Effect/genetics ; Graft vs Leukemia Effect/immunology ; Interleukin-6/genetics ; Interleukins/genetics ; Interleukins/immunology ; Mice ; Mice, Transgenic ; Receptors, Interleukin-6/genetics ; Receptors, Interleukin-6/immunology ; Signal Transduction/genetics ; Skin Diseases/genetics ; Skin Diseases/pathology ; Th17 Cells/immunology ; Th17 Cells/pathology
Czasopismo naukowe
Tytuł :
One week of magnesium supplementation lowers IL-6, muscle soreness and increases post-exercise blood glucose in response to downhill running.
Autorzy :
Steward CJ; Department of Exercise Physiology, Beijing Sport University, Beijing, 100084, China.; School of Sport and Exercise Science, University of Worcester, Henwick Grove, Worcester, WR2 6AJ, UK.
Zhou Y; Department of Exercise Physiology, Beijing Sport University, Beijing, 100084, China.
Keane G; School of Sport and Exercise Science, University of Worcester, Henwick Grove, Worcester, WR2 6AJ, UK.
Cook MD; School of Sport and Exercise Science, University of Worcester, Henwick Grove, Worcester, WR2 6AJ, UK.
Liu Y; Department of Exercise Physiology, Beijing Sport University, Beijing, 100084, China.
Cullen T; School of Sport and Exercise Science, University of Worcester, Henwick Grove, Worcester, WR2 6AJ, UK. .; Centre for Sport, Exercise and Life Sciences, Coventry University, Priory Street, Coventry, CV1 5FB, UK. .
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Źródło :
European journal of applied physiology [Eur J Appl Physiol] 2019 Dec; Vol. 119 (11-12), pp. 2617-2627. Date of Electronic Publication: 2019 Oct 17.
Typ publikacji :
Clinical Trial; Journal Article
MeSH Terms :
Blood Glucose/*drug effects
Exercise/*physiology
Interleukin-6/*metabolism
Magnesium/*administration & dosage
Muscle, Skeletal/*drug effects
Myalgia/*drug therapy
Adult ; Blood Glucose/metabolism ; Creatine Kinase/metabolism ; Cross-Over Studies ; Dietary Supplements ; Double-Blind Method ; Humans ; Inflammation/drug therapy ; Inflammation/metabolism ; Male ; Muscle, Skeletal/metabolism ; Myalgia/metabolism ; Receptors, Interleukin-6/metabolism ; Running/physiology
Czasopismo naukowe
Tytuł :
IL-6 Trans-signaling Controls Liver Regeneration After Partial Hepatectomy.
Autorzy :
Fazel Modares N; Institute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany.
Polz R; Institute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany.
Haghighi F; Institute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany.
Lamertz L; Institute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany.
Behnke K; Institute of Molecular Medicine II, Medical Faculty, Heinrich-Heine-University, Düsseldorf, Germany.
Zhuang Y; Institute of Molecular Medicine II, Medical Faculty, Heinrich-Heine-University, Düsseldorf, Germany.
Kordes C; Clinic for Gastroenterology, Hepatology and Infectious Diseases, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany.
Häussinger D; Clinic for Gastroenterology, Hepatology and Infectious Diseases, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany.
Sorg UR; Institute of Medical Microbiology and Hospital Hygiene, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany.
Pfeffer K; Institute of Medical Microbiology and Hospital Hygiene, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany.
Floss DM; Institute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany.
Moll JM; Institute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany.
Piekorz RP; Institute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany.
Ahmadian MR; Institute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany.
Lang PA; Institute of Molecular Medicine II, Medical Faculty, Heinrich-Heine-University, Düsseldorf, Germany.
Scheller J; Institute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany.
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Źródło :
Hepatology (Baltimore, Md.) [Hepatology] 2019 Dec; Vol. 70 (6), pp. 2075-2091. Date of Electronic Publication: 2019 Jul 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Hepatectomy*
Interleukin-6/*physiology
Liver Regeneration/*physiology
Animals ; Hepatic Stellate Cells/physiology ; Hepatocyte Growth Factor/physiology ; Mice ; Mice, Inbred C57BL ; Receptors, Interleukin-6/blood ; Receptors, Interleukin-6/physiology ; Signal Transduction/physiology
Czasopismo naukowe

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