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Tytuł :
Cytokine mRNA Degradation in Cardiomyocytes Restrains Sterile Inflammation in Pressure-Overloaded Hearts.
Autorzy :
Omiya S; The School of Cardiovascular Medicine and Sciences, King's College London British Heart Foundation Centre of Excellence, United Kingdom (S.O., Y.O., M.T., T.M., J.I., Y.T., K.N., A.M.S., K.O.).
Omori Y; The School of Cardiovascular Medicine and Sciences, King's College London British Heart Foundation Centre of Excellence, United Kingdom (S.O., Y.O., M.T., T.M., J.I., Y.T., K.N., A.M.S., K.O.).
Taneike M; The School of Cardiovascular Medicine and Sciences, King's College London British Heart Foundation Centre of Excellence, United Kingdom (S.O., Y.O., M.T., T.M., J.I., Y.T., K.N., A.M.S., K.O.).
Murakawa T; The School of Cardiovascular Medicine and Sciences, King's College London British Heart Foundation Centre of Excellence, United Kingdom (S.O., Y.O., M.T., T.M., J.I., Y.T., K.N., A.M.S., K.O.).
Ito J; The School of Cardiovascular Medicine and Sciences, King's College London British Heart Foundation Centre of Excellence, United Kingdom (S.O., Y.O., M.T., T.M., J.I., Y.T., K.N., A.M.S., K.O.).
Tanada Y; The School of Cardiovascular Medicine and Sciences, King's College London British Heart Foundation Centre of Excellence, United Kingdom (S.O., Y.O., M.T., T.M., J.I., Y.T., K.N., A.M.S., K.O.).
Nishida K; The School of Cardiovascular Medicine and Sciences, King's College London British Heart Foundation Centre of Excellence, United Kingdom (S.O., Y.O., M.T., T.M., J.I., Y.T., K.N., A.M.S., K.O.).
Yamaguchi O; Department of Cardiovascular Medicine, Graduate School of Medicine (O.Y.), Osaka University, Suita, Japan.
Satoh T; Laboratory of Host Defense, Research Institute for Microbial Diseases (T.S., S.A.), Osaka University, Suita, Japan.
Shah AM; The School of Cardiovascular Medicine and Sciences, King's College London British Heart Foundation Centre of Excellence, United Kingdom (S.O., Y.O., M.T., T.M., J.I., Y.T., K.N., A.M.S., K.O.).
Akira S; Laboratory of Host Defense, Research Institute for Microbial Diseases (T.S., S.A.), Osaka University, Suita, Japan.
Otsu K; The School of Cardiovascular Medicine and Sciences, King's College London British Heart Foundation Centre of Excellence, United Kingdom (S.O., Y.O., M.T., T.M., J.I., Y.T., K.N., A.M.S., K.O.).
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Źródło :
Circulation [Circulation] 2020 Feb 25; Vol. 141 (8), pp. 667-677. Date of Electronic Publication: 2020 Jan 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Inflammation/*pathology
Interleukin-6/*metabolism
Myocytes, Cardiac/*metabolism
RNA, Messenger/*metabolism
Ribonucleases/*genetics
Animals ; Antibodies/immunology ; Antibodies/therapeutic use ; Cardiomyopathy, Dilated/etiology ; Cardiomyopathy, Dilated/metabolism ; Cardiomyopathy, Dilated/pathology ; Genetic Vectors/metabolism ; Heart Failure/etiology ; Heart Failure/prevention & control ; Inflammation/prevention & control ; Interleukin-6/genetics ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Receptors, Interleukin-6/immunology ; Ribonucleases/deficiency ; Ribonucleases/metabolism ; Up-Regulation
Czasopismo naukowe
Tytuł :
Blood Vitronectin Induces Detrimental Brain Interleukin-6 and Correlates With Outcomes After Stroke Only in Female Mice.
Autorzy :
Jia C; From the Department of Biomedical Sciences, Quillen College of Medicine, East Tennessee State University, Johnson City.
Malone HM; From the Department of Biomedical Sciences, Quillen College of Medicine, East Tennessee State University, Johnson City.
Keasey MP; From the Department of Biomedical Sciences, Quillen College of Medicine, East Tennessee State University, Johnson City.
Lovins C; From the Department of Biomedical Sciences, Quillen College of Medicine, East Tennessee State University, Johnson City.
Elam J; From the Department of Biomedical Sciences, Quillen College of Medicine, East Tennessee State University, Johnson City.
Hagg T; From the Department of Biomedical Sciences, Quillen College of Medicine, East Tennessee State University, Johnson City.
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Źródło :
Stroke [Stroke] 2020 May; Vol. 51 (5), pp. 1587-1595. Date of Electronic Publication: 2020 Apr 21.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Blood-Brain Barrier/*metabolism
Infarction, Middle Cerebral Artery/*genetics
Inflammation/*genetics
Interleukin-6/*genetics
Vitronectin/*genetics
Animals ; Ciliary Neurotrophic Factor/genetics ; Ciliary Neurotrophic Factor/metabolism ; Female ; Infarction, Middle Cerebral Artery/metabolism ; Infarction, Middle Cerebral Artery/pathology ; Infarction, Middle Cerebral Artery/physiopathology ; Inflammation/metabolism ; Interleukin-6/metabolism ; Leukemia Inhibitory Factor/genetics ; Leukemia Inhibitory Factor/metabolism ; Macrophages/metabolism ; Macrophages/pathology ; Male ; Mice ; Mice, Knockout ; Microglia/metabolism ; Microglia/pathology ; RNA, Messenger/metabolism ; Sex Factors ; Stroke/genetics ; Stroke/metabolism ; Stroke/pathology ; Stroke/physiopathology ; Vitronectin/blood ; Vitronectin/metabolism
Czasopismo naukowe
Tytuł :
Interleukin-6 Receptor Signaling and Abdominal Aortic Aneurysm Growth Rates.
Autorzy :
Paige E; National Centre for Epidemiology and Population Health, Research School of Population Health, The Australian National University, Canberra, Australia (E.P.).; BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care (E.P., M.S., J.E.P., B.B.S., A.S.B., J.D., D.F.F., D.S.P.), University of Cambridge, United Kingdom.
Clément M; Division of Cardiovascular Medicine (M.C., F.L., J.R., C.G., A.F., J.H., Z.M.), University of Cambridge, United Kingdom.
Lareyre F; Division of Cardiovascular Medicine (M.C., F.L., J.R., C.G., A.F., J.H., Z.M.), University of Cambridge, United Kingdom.; Université Côte d'Azur, Institut National de la Sante et de la Recherche Medicale, Centre Mediterranéen de Recherche Moleculaire (F.L., J.R.).; University Hospital of Nice, France (F.L., J.R.).
Sweeting M; BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care (E.P., M.S., J.E.P., B.B.S., A.S.B., J.D., D.F.F., D.S.P.), University of Cambridge, United Kingdom.; Department of Health Sciences (M.S.), University of Leicester.
Raffort J; Division of Cardiovascular Medicine (M.C., F.L., J.R., C.G., A.F., J.H., Z.M.), University of Cambridge, United Kingdom.; Université Côte d'Azur, Institut National de la Sante et de la Recherche Medicale, Centre Mediterranéen de Recherche Moleculaire (F.L., J.R.).; University Hospital of Nice, France (F.L., J.R.).
Grenier C; Division of Cardiovascular Medicine (M.C., F.L., J.R., C.G., A.F., J.H., Z.M.), University of Cambridge, United Kingdom.
Finigan A; Division of Cardiovascular Medicine (M.C., F.L., J.R., C.G., A.F., J.H., Z.M.), University of Cambridge, United Kingdom.
Harrison J; Division of Cardiovascular Medicine (M.C., F.L., J.R., C.G., A.F., J.H., Z.M.), University of Cambridge, United Kingdom.
Peters JE; BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care (E.P., M.S., J.E.P., B.B.S., A.S.B., J.D., D.F.F., D.S.P.), University of Cambridge, United Kingdom.; British Heart Foundation Centre of Excellence, Division of Cardiovascular Medicine, Addenbrooke's Hospital, Cambridge, UK (J.E.P., A.S.B., S.C.H., J.D., D.F.F., D.S.P., Z.M.).
Sun BB; BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care (E.P., M.S., J.E.P., B.B.S., A.S.B., J.D., D.F.F., D.S.P.), University of Cambridge, United Kingdom.
Butterworth AS; BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care (E.P., M.S., J.E.P., B.B.S., A.S.B., J.D., D.F.F., D.S.P.), University of Cambridge, United Kingdom.; British Heart Foundation Centre of Excellence, Division of Cardiovascular Medicine, Addenbrooke's Hospital, Cambridge, UK (J.E.P., A.S.B., S.C.H., J.D., D.F.F., D.S.P., Z.M.).; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Cambridge, United Kingdom (A.S.B., J.D.).
Harrison SC; Department of Cardiovascular Sciences, NIHR Leicester Biomedical Research Centre (S.C.H., M.J.B.), University of Leicester.; British Heart Foundation Centre of Excellence, Division of Cardiovascular Medicine, Addenbrooke's Hospital, Cambridge, UK (J.E.P., A.S.B., S.C.H., J.D., D.F.F., D.S.P., Z.M.).
Bown MJ; Department of Cardiovascular Sciences, NIHR Leicester Biomedical Research Centre (S.C.H., M.J.B.), University of Leicester.
Lindholt JS; Department of Cardiovascular and Thoracic Surgery, Elitary Research Centre of Individualised Medicine in Arterial Disease, Odense University Hospital, Denmark (J.S.L.).
Badger SA; Regional Vascular Surgery Unit, Belfast Health and Social Care Trust, United Kingdom (S.A.B.).
Kullo IJ; Department of Cardiovascular Medicine, Gonda Vascular Center, Mayo Clinic, Rochester, MN (I.J.K.).
Powell J; Faculty of Medicine, Department of Surgery and Cancer, Imperial College London, United Kingdom (J.P.).
Norman PE; Medical School, University of Western Australia, Perth, Australia (P.E.N.).
Scott DJA; Leeds Vascular Institute, Leeds General Infirmary (D.J.A.S., M.A.B.).; Leeds Institute of Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, United Kingdom (D.J.A.S., M.A.B.).
Bailey MA; Leeds Vascular Institute, Leeds General Infirmary (D.J.A.S., M.A.B.).; Leeds Institute of Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, United Kingdom (D.J.A.S., M.A.B.).
Rose-John S; Department of Biochemistry, Christian-Albrechts-University, Kiel, Germany (S.R.-J.).
Danesh J; BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care (E.P., M.S., J.E.P., B.B.S., A.S.B., J.D., D.F.F., D.S.P.), University of Cambridge, United Kingdom.; British Heart Foundation Centre of Excellence, Division of Cardiovascular Medicine, Addenbrooke's Hospital, Cambridge, UK (J.E.P., A.S.B., S.C.H., J.D., D.F.F., D.S.P., Z.M.).; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Cambridge, United Kingdom (A.S.B., J.D.).; Department of Human Genetics, Wellcome Sanger Institute, Hinxton, United Kingdom (J.D.).
Freitag DF; BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care (E.P., M.S., J.E.P., B.B.S., A.S.B., J.D., D.F.F., D.S.P.), University of Cambridge, United Kingdom.; British Heart Foundation Centre of Excellence, Division of Cardiovascular Medicine, Addenbrooke's Hospital, Cambridge, UK (J.E.P., A.S.B., S.C.H., J.D., D.F.F., D.S.P., Z.M.).
Paul DS; BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care (E.P., M.S., J.E.P., B.B.S., A.S.B., J.D., D.F.F., D.S.P.), University of Cambridge, United Kingdom.; British Heart Foundation Centre of Excellence, Division of Cardiovascular Medicine, Addenbrooke's Hospital, Cambridge, UK (J.E.P., A.S.B., S.C.H., J.D., D.F.F., D.S.P., Z.M.).
Mallat Z; Division of Cardiovascular Medicine (M.C., F.L., J.R., C.G., A.F., J.H., Z.M.), University of Cambridge, United Kingdom.; British Heart Foundation Centre of Excellence, Division of Cardiovascular Medicine, Addenbrooke's Hospital, Cambridge, UK (J.E.P., A.S.B., S.C.H., J.D., D.F.F., D.S.P., Z.M.).; Institut National de la Santé et de la Recherche Médicale, Paris Cardiovascular Research Center, France (Z.M.).
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Źródło :
Circulation. Genomic and precision medicine [Circ Genom Precis Med] 2019 Feb; Vol. 12 (2), pp. e002413.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Aortic Aneurysm, Abdominal/*pathology
Receptors, Interleukin-6/*metabolism
Alleles ; Angiotensin II/toxicity ; Animals ; Antibodies/immunology ; Aortic Aneurysm, Abdominal/metabolism ; Aortic Aneurysm, Abdominal/mortality ; Biomarkers/metabolism ; Disease Models, Animal ; Humans ; Interleukin-6/blood ; Linear Models ; Mice ; Polymorphism, Single Nucleotide ; Receptors, Interleukin-6/genetics ; Receptors, Interleukin-6/immunology ; Signal Transduction ; Survival Rate ; Transforming Growth Factor beta/immunology
Czasopismo naukowe
Tytuł :
IL (Interleukin)-6 Contributes to Deep Vein Thrombosis and Is Negatively Regulated by miR-338-5p.
Autorzy :
Zhang Y; From the School of Medicine and Life Sciences, University of Jinan-Shandong Academy of Medical Sciences, China (Y.Z., C.C.).; Laboratory for Molecular Immunology, Institute of Basic Medicine, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China (Y.Z., Z.Z., R.W., S.S., C.C., L.Z., X.Z., Q.G., X.L.).
Zhang Z; Laboratory for Molecular Immunology, Institute of Basic Medicine, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China (Y.Z., Z.Z., R.W., S.S., C.C., L.Z., X.Z., Q.G., X.L.).
Wei R; Laboratory for Molecular Immunology, Institute of Basic Medicine, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China (Y.Z., Z.Z., R.W., S.S., C.C., L.Z., X.Z., Q.G., X.L.).
Miao X; Department of Peripheral Vascular Disease, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, China (X.M., G.L., B.W.).
Sun S; Laboratory for Molecular Immunology, Institute of Basic Medicine, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China (Y.Z., Z.Z., R.W., S.S., C.C., L.Z., X.Z., Q.G., X.L.).; Department of Cardiology, The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences, The State and Shandong Province Joint Key Laboratory of Translational Cardiovascular Medicine, Qilu Hospital of Shandong University, Jinan (S.S.).
Liang G; Department of Peripheral Vascular Disease, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, China (X.M., G.L., B.W.).
Chu C; From the School of Medicine and Life Sciences, University of Jinan-Shandong Academy of Medical Sciences, China (Y.Z., C.C.).; Laboratory for Molecular Immunology, Institute of Basic Medicine, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China (Y.Z., Z.Z., R.W., S.S., C.C., L.Z., X.Z., Q.G., X.L.).
Zhao L; Laboratory for Molecular Immunology, Institute of Basic Medicine, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China (Y.Z., Z.Z., R.W., S.S., C.C., L.Z., X.Z., Q.G., X.L.).
Zhu X; Laboratory for Molecular Immunology, Institute of Basic Medicine, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China (Y.Z., Z.Z., R.W., S.S., C.C., L.Z., X.Z., Q.G., X.L.).
Guo Q; Laboratory for Molecular Immunology, Institute of Basic Medicine, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China (Y.Z., Z.Z., R.W., S.S., C.C., L.Z., X.Z., Q.G., X.L.).
Wang B; Department of Peripheral Vascular Disease, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, China (X.M., G.L., B.W.).
Li X; Laboratory for Molecular Immunology, Institute of Basic Medicine, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China (Y.Z., Z.Z., R.W., S.S., C.C., L.Z., X.Z., Q.G., X.L.).
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Źródło :
Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2020 Feb; Vol. 40 (2), pp. 323-334. Date of Electronic Publication: 2019 Dec 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation*
Interleukin-6/*genetics
Lower Extremity/*blood supply
MicroRNAs/*genetics
Venous Thrombosis/*genetics
Angiography ; Animals ; Cells, Cultured ; Enzyme-Linked Immunosorbent Assay ; Female ; Humans ; Interleukin-6/biosynthesis ; Male ; Mice ; Mice, Inbred C57BL ; MicroRNAs/biosynthesis ; Middle Aged ; RNA/genetics ; Retrospective Studies ; Ultrasonography, Doppler, Color ; Venous Thrombosis/diagnosis ; Venous Thrombosis/metabolism
Czasopismo naukowe
Tytuł :
Human Cardiac Mesenchymal Stem Cells Remodel in Disease and Can Regulate Arrhythmia Substrates.
Autorzy :
Sattayaprasert P; Heart and Vascular Research Center, MetroHealth Campus, Case Western Reserve University, Cleveland, OH (P.S., S.K.V., M.H., K.R.L.).
Vasireddi SK; Heart and Vascular Research Center, MetroHealth Campus, Case Western Reserve University, Cleveland, OH (P.S., S.K.V., M.H., K.R.L.).
Bektik E; Department of Cardiology, Boston Children's Hospital, Harvard Medical School, Boston, MA (E.B.).
Jeon O; Departments of Biomedical Engineering (O.J., E.A.), University of Illinois at Chicago.
Hajjiri M; Heart and Vascular Research Center, MetroHealth Campus, Case Western Reserve University, Cleveland, OH (P.S., S.K.V., M.H., K.R.L.).
Mackall JA; Harrington Heart & Vascular Institute, University Hospitals Cleveland Medical Center (J.A.M.).
Moravec CS; Cardiovascular & Metabolic Sciences, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland (C.S.M.).
Alsberg E; Departments of Biomedical Engineering (O.J., E.A.), University of Illinois at Chicago.; Orthopaedics (E.A.), University of Illinois at Chicago.; Pharmacology (E.A.), University of Illinois at Chicago.; Mechanical & Industrial Engineering (E.A.), University of Illinois at Chicago.
Fu J; Department of Physiology & Cell Biology, The Dorothy M. Davis Heart & Lung Research Institute, The Ohio State University, Columbus (J.F.).
Laurita KR; Heart and Vascular Research Center, MetroHealth Campus, Case Western Reserve University, Cleveland, OH (P.S., S.K.V., M.H., K.R.L.).
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Źródło :
Circulation. Arrhythmia and electrophysiology [Circ Arrhythm Electrophysiol] 2020 Oct; Vol. 13 (10), pp. e008740. Date of Electronic Publication: 2020 Jul 29.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Action Potentials*
Calcium Signaling*
Paracrine Communication*
Arrhythmias, Cardiac/*metabolism
Heart Failure/*metabolism
Induced Pluripotent Stem Cells/*metabolism
Inflammation Mediators/*metabolism
Mesenchymal Stem Cells/*metabolism
Myocytes, Cardiac/*metabolism
Adult ; Aged ; Arrhythmias, Cardiac/pathology ; Arrhythmias, Cardiac/physiopathology ; Case-Control Studies ; Cell Lineage ; Cells, Cultured ; Coculture Techniques ; Female ; Heart Failure/pathology ; Heart Failure/physiopathology ; Humans ; Induced Pluripotent Stem Cells/pathology ; Interleukin-1beta/metabolism ; Interleukin-6/metabolism ; Kinetics ; Male ; Mesenchymal Stem Cells/pathology ; Middle Aged ; Myocytes, Cardiac/pathology ; Phenotype
Czasopismo naukowe
Tytuł :
Aerobic Exercise Induces Cardiac Fat Loss and Alters Cardiac Muscle Mass Through an Interleukin-6 Receptor-Dependent Mechanism: Cardiac Analysis of a Double-Blind Randomized Controlled Clinical Trial in Abdominally Obese Humans.
Autorzy :
Christensen RH; Centre of Inflammation and Metabolism and the Centre for Physical Activity Research, Rigshospitalet, University of Copenhagen, Denmark (R.H.C., L.L.L., A.-S.W.-N., G.E.L., M.R.-L., K.K., R.K.-M., B.K.P., H.E.).
Lehrskov LL; Centre of Inflammation and Metabolism and the Centre for Physical Activity Research, Rigshospitalet, University of Copenhagen, Denmark (R.H.C., L.L.L., A.-S.W.-N., G.E.L., M.R.-L., K.K., R.K.-M., B.K.P., H.E.).
Wedell-Neergaard AS; Centre of Inflammation and Metabolism and the Centre for Physical Activity Research, Rigshospitalet, University of Copenhagen, Denmark (R.H.C., L.L.L., A.-S.W.-N., G.E.L., M.R.-L., K.K., R.K.-M., B.K.P., H.E.).
Legaard GE; Centre of Inflammation and Metabolism and the Centre for Physical Activity Research, Rigshospitalet, University of Copenhagen, Denmark (R.H.C., L.L.L., A.-S.W.-N., G.E.L., M.R.-L., K.K., R.K.-M., B.K.P., H.E.).
Ried-Larsen M; Centre of Inflammation and Metabolism and the Centre for Physical Activity Research, Rigshospitalet, University of Copenhagen, Denmark (R.H.C., L.L.L., A.-S.W.-N., G.E.L., M.R.-L., K.K., R.K.-M., B.K.P., H.E.).
Karstoft K; Centre of Inflammation and Metabolism and the Centre for Physical Activity Research, Rigshospitalet, University of Copenhagen, Denmark (R.H.C., L.L.L., A.-S.W.-N., G.E.L., M.R.-L., K.K., R.K.-M., B.K.P., H.E.).
Krogh-Madsen R; Centre of Inflammation and Metabolism and the Centre for Physical Activity Research, Rigshospitalet, University of Copenhagen, Denmark (R.H.C., L.L.L., A.-S.W.-N., G.E.L., M.R.-L., K.K., R.K.-M., B.K.P., H.E.).
Pedersen BK; Centre of Inflammation and Metabolism and the Centre for Physical Activity Research, Rigshospitalet, University of Copenhagen, Denmark (R.H.C., L.L.L., A.-S.W.-N., G.E.L., M.R.-L., K.K., R.K.-M., B.K.P., H.E.).
Ellingsgaard H; Centre of Inflammation and Metabolism and the Centre for Physical Activity Research, Rigshospitalet, University of Copenhagen, Denmark (R.H.C., L.L.L., A.-S.W.-N., G.E.L., M.R.-L., K.K., R.K.-M., B.K.P., H.E.).
Rosenmeier JB; Department of Cardiology, Copenhagen University Hospital Bispebjerg, Denmark (J.B.R.).
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Źródło :
Circulation [Circulation] 2019 Nov 12; Vol. 140 (20), pp. 1684-1686. Date of Electronic Publication: 2019 Nov 11.
Typ publikacji :
Letter; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Adiposity*
Exercise Therapy*
Adipose Tissue/*metabolism
Myocardium/*metabolism
Obesity, Abdominal/*therapy
Receptors, Interleukin-6/*metabolism
Adipose Tissue/physiopathology ; Adult ; Antibodies, Monoclonal, Humanized/administration & dosage ; Double-Blind Method ; Female ; Humans ; Male ; Middle Aged ; Obesity, Abdominal/diagnosis ; Obesity, Abdominal/metabolism ; Obesity, Abdominal/physiopathology ; Receptors, Interleukin-6/antagonists & inhibitors ; Signal Transduction ; Time Factors ; Treatment Outcome
Raport
Tytuł :
Interleukin-6 trans-signaling and pathological low back pain in patients with Paget disease of bone.
Autorzy :
Rendina D; Department of Medicine and Surgery, Federico II University, Naples, Italy.
De Filippo G; Department of Medicine and Surgery, Federico II University, Naples, Italy.; Assistance Publique-Hôpitaux de Paris, CHU Bicêtre, Service de Médecine des Adolescents, Le Kremlin-Bicêtre, France.
Postiglione L; Department of Translational Medical Sciences, Medical School, 'Federico II' University, Naples, Italy.
Covelli B; Department of Translational Medical Sciences, Medical School, 'Federico II' University, Naples, Italy.
Ricciardone M; Department of Translational Medical Sciences, Medical School, 'Federico II' University, Naples, Italy.
Guillaume S; Assistance Publique-Hôpitaux de Paris, CHU Bicêtre, Service de Médecine des Adolescents, Le Kremlin-Bicêtre, France.
Di Spigna G; Department of Translational Medical Sciences, Medical School, 'Federico II' University, Naples, Italy.
Selleri C; Department of Medicine and Surgery, University of Salerno, Salerno, Italy.
Merlotti D; Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy.
Bianciardi S; Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy.
Materozzi M; Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy.
Muscariello R; Department of Medicine and Surgery, Federico II University, Naples, Italy.
De Pascale F; Department of Medicine and Surgery, Federico II University, Naples, Italy.
DʼElia L; Department of Medicine and Surgery, Federico II University, Naples, Italy.
Nuti R; Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy.
Strazzullo P; Department of Medicine and Surgery, Federico II University, Naples, Italy.
Gennari L; Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy.
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Źródło :
Pain [Pain] 2018 Aug; Vol. 159 (8), pp. 1664-1673.
Typ publikacji :
Journal Article
MeSH Terms :
Interleukin-6/*blood
Low Back Pain/*blood
Osteitis Deformans/*blood
Signal Transduction/*physiology
Aged ; Cytokine Receptor gp130/blood ; Female ; Humans ; Low Back Pain/complications ; Male ; Middle Aged ; Osteitis Deformans/complications ; Receptors, Interleukin-6/blood
Czasopismo naukowe
Tytuł :
Association of elevated inflammatory markers and severe COVID-19: A meta-analysis.
Autorzy :
Ji P; Department of Emergency Medicine, The Second Affiliated Hospital of Guangxi Medical University, Nanning, China.
Zhu J
Zhong Z
Li H
Pang J
Li B
Zhang J
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Źródło :
Medicine [Medicine (Baltimore)] 2020 Nov 20; Vol. 99 (47), pp. e23315.
Typ publikacji :
Journal Article; Meta-Analysis; Review
MeSH Terms :
Betacoronavirus*
Severity of Illness Index*
Biomarkers/*blood
Coronavirus Infections/*blood
Inflammation Mediators/*blood
Pneumonia, Viral/*blood
Adult ; Aged ; Blood Sedimentation ; C-Reactive Protein/analysis ; Coronavirus Infections/mortality ; Disease Progression ; Female ; Humans ; Inflammation ; Interleukin-10/blood ; Interleukin-6/blood ; Leukocyte Count ; Male ; Middle Aged ; Pandemics ; Pneumonia, Viral/mortality ; Procalcitonin/blood
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Endotheliopathy Is Induced by Plasma From Critically Ill Patients and Associated With Organ Failure in Severe COVID-19.
Autorzy :
Rauch A; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011- EGID, F-59000 Lille, France (A.R., A. Dupont, M.M., E.J., D.C., F.L., B.S., E.V.B., F.V., S. Susen).
Dupont A; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011- EGID, F-59000 Lille, France (A.R., A. Dupont, M.M., E.J., D.C., F.L., B.S., E.V.B., F.V., S. Susen).
Goutay J; Intensive Care Department, Pôle de Réanimation (J.G., M.C.), Centre Hospitalier Universitaire Lille, France.
Caplan M; Intensive Care Department, Pôle de Réanimation (J.G., M.C.), Centre Hospitalier Universitaire Lille, France.
Staessens S; Centre national de la recherche scientifique, Surgical Critical Care, Department of Anesthesiology and Critical Care, U1019 - Unité mixte de recherche 9017 - Center for Infection and Immunity of Lille (E.K.), Institut Pasteur de Lille, UMR1011-EGID (S. Staessens, D.C., B.S.), Univ. Lille, CHU Lille, France.; Laboratory for Thrombosis Research, Katholieke Universiteit Leuven Campus Kulak Kortrijk, Belgium (S. Staessens, S.F.D.M.).
Moussa M; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011- EGID, F-59000 Lille, France (A.R., A. Dupont, M.M., E.J., D.C., F.L., B.S., E.V.B., F.V., S. Susen).; Surgical Critical Care, Department of Anesthesiology and Critical Care (M.M.), Univ. Lille, CHU Lille, France.
Jeanpierre E; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011- EGID, F-59000 Lille, France (A.R., A. Dupont, M.M., E.J., D.C., F.L., B.S., E.V.B., F.V., S. Susen).
Corseaux D; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011- EGID, F-59000 Lille, France (A.R., A. Dupont, M.M., E.J., D.C., F.L., B.S., E.V.B., F.V., S. Susen).; Centre national de la recherche scientifique, Surgical Critical Care, Department of Anesthesiology and Critical Care, U1019 - Unité mixte de recherche 9017 - Center for Infection and Immunity of Lille (E.K.), Institut Pasteur de Lille, UMR1011-EGID (S. Staessens, D.C., B.S.), Univ. Lille, CHU Lille, France.
Lefevre G; Institut d'Immunologie, U1286 - INFINITE - Institute for Translational Research in Inflammation (G.L.), ULR 2694 - METRICS: Évaluation des technologies de santé et des pratiques médicales (A. Duhamel, J.L.), Univ. Lille, CHU Lille, France.
Lassalle F; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011- EGID, F-59000 Lille, France (A.R., A. Dupont, M.M., E.J., D.C., F.L., B.S., E.V.B., F.V., S. Susen).
Faure K; Department of Infectious Diseases (K.F.), Univ. Lille, CHU Lille, France.
Lambert M; Department of Internal Medicine, Institut national de la santé et de la recherche médicale U 1167 (M.L.), Univ. Lille, CHU Lille, France.
Duhamel A; Institut d'Immunologie, U1286 - INFINITE - Institute for Translational Research in Inflammation (G.L.), ULR 2694 - METRICS: Évaluation des technologies de santé et des pratiques médicales (A. Duhamel, J.L.), Univ. Lille, CHU Lille, France.
Labreuche J; Institut d'Immunologie, U1286 - INFINITE - Institute for Translational Research in Inflammation (G.L.), ULR 2694 - METRICS: Évaluation des technologies de santé et des pratiques médicales (A. Duhamel, J.L.), Univ. Lille, CHU Lille, France.
Garrigue D; Surgical Critical Care, Department of Anesthesiology and Critical Care (D.G.), Centre Hospitalier Universitaire Lille, France.
De Meyer SF; Laboratory for Thrombosis Research, Katholieke Universiteit Leuven Campus Kulak Kortrijk, Belgium (S. Staessens, S.F.D.M.).
Staels B; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011- EGID, F-59000 Lille, France (A.R., A. Dupont, M.M., E.J., D.C., F.L., B.S., E.V.B., F.V., S. Susen).; Centre national de la recherche scientifique, Surgical Critical Care, Department of Anesthesiology and Critical Care, U1019 - Unité mixte de recherche 9017 - Center for Infection and Immunity of Lille (E.K.), Institut Pasteur de Lille, UMR1011-EGID (S. Staessens, D.C., B.S.), Univ. Lille, CHU Lille, France.
Van Belle E; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011- EGID, F-59000 Lille, France (A.R., A. Dupont, M.M., E.J., D.C., F.L., B.S., E.V.B., F.V., S. Susen).; Department Cardiology (E.V.B., F.V.), Univ. Lille, CHU Lille, France.
Vincent F; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011- EGID, F-59000 Lille, France (A.R., A. Dupont, M.M., E.J., D.C., F.L., B.S., E.V.B., F.V., S. Susen).
Kipnis E; Centre national de la recherche scientifique, Surgical Critical Care, Department of Anesthesiology and Critical Care, U1019 - Unité mixte de recherche 9017 - Center for Infection and Immunity of Lille (E.K.), Institut Pasteur de Lille, UMR1011-EGID (S. Staessens, D.C., B.S.), Univ. Lille, CHU Lille, France.
Lenting PJ
Poissy J; Institut national de la santé et de la recherche médicale U1285, Pôle de réanimation, Centre national de la recherche scientifique, Unité mixte de recherche 8576 - Unité de Glycobiologie Structurale et Fonctionnelle (J.P.), Univ. Lille, CHU Lille, France.
Susen S; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011- EGID, F-59000 Lille, France (A.R., A. Dupont, M.M., E.J., D.C., F.L., B.S., E.V.B., F.V., S. Susen).
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Corporate Authors :
Lille COVID Research Network (LICORNE)
Members of the LICORNE Scientific Committee
Źródło :
Circulation [Circulation] 2020 Nov 10; Vol. 142 (19), pp. 1881-1884. Date of Electronic Publication: 2020 Sep 24.
Typ publikacji :
Letter; Research Support, Non-U.S. Gov't
MeSH Terms :
Coronavirus Infections/*pathology
Plasma/*chemistry
Pneumonia, Viral/*pathology
Betacoronavirus/isolation & purification ; Cell Survival ; Cell-Free Nucleic Acids/metabolism ; Cells, Cultured ; Coronavirus Infections/complications ; Coronavirus Infections/virology ; Critical Illness ; Endothelial Cells/cytology ; Endothelial Cells/metabolism ; Humans ; Interleukin-6/metabolism ; Microvessels/cytology ; Multiple Organ Failure/etiology ; Pandemics ; Plasma/metabolism ; Pneumonia, Viral/complications ; Pneumonia, Viral/virology ; Severity of Illness Index ; Syndecan-1/metabolism
SCR Disease Name :
COVID-19
Raport
Tytuł :
Treatment of Cytokine Storm in COVID-19 Patients With Immunomodulatory Therapy.
Autorzy :
Yessayan L; From the Division of Nephrology, Department of Medicine, University of Michigan, Ann Arbor, MI.
Szamosfalvi B; From the Division of Nephrology, Department of Medicine, University of Michigan, Ann Arbor, MI.
Napolitano L; Division of Acute Care Surgery, Department of Surgery, University of Michigan, Ann Arbor, MI.
Singer B; Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Michigan, Ann Arbor, MI.
Kurabayashi K; Department of Mechanical Engineering, University of Michigan, Ann Arbor, Michigan.; Department of Electrical Engineering and Computer Science, University of Michigan, Ann Arbor, Michigan.
Song Y; Department of Mechanical Engineering, University of Michigan, Ann Arbor, Michigan.
Westover A; From the Division of Nephrology, Department of Medicine, University of Michigan, Ann Arbor, MI.
Humes HD; From the Division of Nephrology, Department of Medicine, University of Michigan, Ann Arbor, MI.
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Źródło :
ASAIO journal (American Society for Artificial Internal Organs : 1992) [ASAIO J] 2020 Nov/Dec; Vol. 66 (10), pp. 1079-1083.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Coronavirus Infections/*immunology
Coronavirus Infections/*therapy
Critical Illness/*therapy
Cytapheresis/*methods
Interleukin-6/*blood
Pneumonia, Viral/*immunology
Pneumonia, Viral/*therapy
Adult ; Betacoronavirus ; Coronavirus Infections/blood ; Critical Care/methods ; Extracorporeal Membrane Oxygenation/methods ; Humans ; Immunomodulation ; Male ; Middle Aged ; Pandemics ; Pneumonia, Viral/blood ; Respiratory Distress Syndrome, Adult/therapy ; Respiratory Distress Syndrome, Adult/virology
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Propofol Attenuates Isoflurane-Induced Neurotoxicity and Cognitive Impairment in Fetal and Offspring Mice.
Autorzy :
Nie Y; From the Department of Anesthesiology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.; Department of Anesthesiology, The First Affiliated Hospital of Xiamen University, Xiamen, Fujian, China.
Li S; From the Department of Anesthesiology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Yan T; From the Department of Anesthesiology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Ma Y; State Key Laboratory of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Ni C; From the Department of Anesthesiology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Wang H; State Key Laboratory of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Zheng H; From the Department of Anesthesiology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
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Źródło :
Anesthesia and analgesia [Anesth Analg] 2020 Nov; Vol. 131 (5), pp. 1616-1625.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Anesthetics, Inhalation/*toxicity
Anesthetics, Intravenous/*pharmacology
Cognitive Dysfunction/*chemically induced
Cognitive Dysfunction/*prevention & control
Isoflurane/*antagonists & inhibitors
Isoflurane/*toxicity
Nervous System Diseases/*chemically induced
Nervous System Diseases/*prevention & control
Propofol/*pharmacology
Animals ; Animals, Newborn ; Brain Chemistry/drug effects ; CA1 Region, Hippocampal/drug effects ; CA1 Region, Hippocampal/metabolism ; Cognitive Dysfunction/psychology ; Disks Large Homolog 4 Protein/metabolism ; Female ; Fetus ; Interleukin-6/metabolism ; Maze Learning ; Mice ; Mice, Inbred C57BL ; Poly (ADP-Ribose) Polymerase-1/metabolism ; Pregnancy ; Synaptophysin/metabolism
Czasopismo naukowe
Tytuł :
Tocilizumab and Remdesivir in a Pregnant Patient With Coronavirus Disease 2019 (COVID-19).
Autorzy :
Naqvi M; Division of Maternal Fetal Medicine, Department of Obstetrics & Gynecology, the Division of Infectious Disease, Department of Internal Medicine, and the Department of Internal Medicine, Cedars Sinai Medical Center, Los Angeles, California.
Zakowski P
Glucksman L
Smithson S
Burwick RM
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Źródło :
Obstetrics and gynecology [Obstet Gynecol] 2020 Nov; Vol. 136 (5), pp. 1025-1029.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Coronavirus Infections*/blood
Coronavirus Infections*/diagnosis
Coronavirus Infections*/drug therapy
Coronavirus Infections*/physiopathology
Pandemics*
Pneumonia, Viral*/blood
Pneumonia, Viral*/diagnosis
Pneumonia, Viral*/drug therapy
Pneumonia, Viral*/etiology
Pneumonia, Viral*/physiopathology
Pregnancy Complications, Infectious*/blood
Pregnancy Complications, Infectious*/diagnosis
Pregnancy Complications, Infectious*/drug therapy
Adenosine Monophosphate/*analogs & derivatives
Alanine/*analogs & derivatives
Antibodies, Monoclonal, Humanized/*administration & dosage
Lung/*diagnostic imaging
Adenosine Monophosphate/administration & dosage ; Adult ; Alanine/administration & dosage ; Antiviral Agents/administration & dosage ; Betacoronavirus/isolation & purification ; C-Reactive Protein/analysis ; Female ; Humans ; Interleukin-6/blood ; Oximetry/methods ; Pregnancy ; Radiography, Thoracic/methods ; Treatment Outcome
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Serum Hydrogen Sulfide and Outcome Association in Pneumonia by the SARS-CoV-2 Coronavirus.
Autorzy :
Renieris G; 4th Department of Internal Medicine, National and Kapodistrian University of Athens, Medical School, Athens, Greece.
Katrini K; 4th Department of Internal Medicine, National and Kapodistrian University of Athens, Medical School, Athens, Greece.
Damoulari C; 4th Department of Internal Medicine, National and Kapodistrian University of Athens, Medical School, Athens, Greece.
Akinosoglou K; Department of Internal Medicine, University of Patras, Medical School, Patras, Greece.
Psarrakis C; 4th Department of Internal Medicine, National and Kapodistrian University of Athens, Medical School, Athens, Greece.
Kyriakopoulou M; 1st Department of Pulmonary Medicine and Intensive Care, National and Kapodistrian University of Athens, Medical School, Athens, Greece.
Dimopoulos G; 2nd Department of Critical Care Medicine, National and Kapodistrian University of Athens, Medical School, Athens, Greece.
Lada M; 2nd Department of Internal Medicine, Sismanogleion Athens General Hospital, Athens, Greece.
Koufargyris P; 4th Department of Internal Medicine, National and Kapodistrian University of Athens, Medical School, Athens, Greece.
Giamarellos-Bourboulis EJ; 4th Department of Internal Medicine, National and Kapodistrian University of Athens, Medical School, Athens, Greece.
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Źródło :
Shock (Augusta, Ga.) [Shock] 2020 Nov; Vol. 54 (5), pp. 633-637.
Typ publikacji :
Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
MeSH Terms :
Coronavirus Infections/*blood
Hydrogen Sulfide/*blood
Pneumonia, Viral/*blood
Aged ; Betacoronavirus/pathogenicity ; Biomarkers/blood ; C-Reactive Protein/metabolism ; Coronavirus Infections/diagnosis ; Coronavirus Infections/mortality ; Coronavirus Infections/virology ; Female ; Greece ; Host-Pathogen Interactions ; Humans ; Interleukin-6/blood ; Lymphocyte Count ; Male ; Middle Aged ; Pandemics ; Patient Admission ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/mortality ; Pneumonia, Viral/virology ; Predictive Value of Tests ; Prognosis ; Risk Factors ; Time Factors ; Up-Regulation
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Pancreatic Inflammation and Proenzyme Activation Are Associated With Clinically Relevant Postoperative Pancreatic Fistulas After Pancreas Resection.
Autorzy :
Wüster C; Department of General- and Visceral Surgery, University of Freiburg Medical Center, Faculty of Medicine, Freiburg, Germany.
Shi H
Kühlbrey CM
Biesel EA
Hopt UT
Fichtner-Feigl S
Wittel UA
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Źródło :
Annals of surgery [Ann Surg] 2020 Nov; Vol. 272 (5), pp. 863-870.
Typ publikacji :
Journal Article; Observational Study
MeSH Terms :
Pancreatectomy*
Pancreatic Fistula/*enzymology
Postoperative Complications/*enzymology
Amylases/metabolism ; Animals ; Cathepsin B/metabolism ; Enzyme Precursors/metabolism ; Female ; Humans ; Inflammation/enzymology ; Interleukin-6/metabolism ; Male ; Mice ; Peroxidase/metabolism ; Prospective Studies ; Trypsin/metabolism ; Trypsinogen/metabolism
Czasopismo naukowe
Tytuł :
COVID-19, Arrhythmic Risk, and Inflammation: Mind the Gap!
Autorzy :
Lazzerini PE; Department of Medical Sciences, Surgery, and Neurosciences, University of Siena, Italy (P.E.L., P.L.C.).
Boutjdir M; VA New York Harbor Healthcare System, SUNY Downstate Medical Center (M.B.).; NYU School of Medicine (M.B.).
Capecchi PL; Department of Medical Sciences, Surgery, and Neurosciences, University of Siena, Italy (P.E.L., P.L.C.).
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Źródło :
Circulation [Circulation] 2020 Jul 07; Vol. 142 (1), pp. 7-9. Date of Electronic Publication: 2020 Apr 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Arrhythmias, Cardiac/*pathology
Coronavirus Infections/*pathology
Pneumonia, Viral/*pathology
Antiviral Agents/chemistry ; Antiviral Agents/metabolism ; Antiviral Agents/therapeutic use ; Arrhythmias, Cardiac/etiology ; Betacoronavirus/isolation & purification ; Coronavirus Infections/complications ; Coronavirus Infections/drug therapy ; Coronavirus Infections/virology ; Cytochrome P-450 CYP2D6/chemistry ; Cytochrome P-450 CYP2D6/metabolism ; Cytochrome P-450 CYP3A/chemistry ; Cytochrome P-450 CYP3A/metabolism ; Electrocardiography ; Humans ; Inflammation ; Interleukin-6/chemistry ; Interleukin-6/metabolism ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/drug therapy ; Pneumonia, Viral/virology ; Risk Factors
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Interleukin 6 decreases nociceptor expression of the potassium channel KV1.4 in a rat model of hand-arm vibration syndrome.
Autorzy :
Alvarez P; Departments of Oral and Maxillofacial Surgery and.
Bogen O; Departments of Oral and Maxillofacial Surgery and.
Levine JD; Departments of Oral and Maxillofacial Surgery and.; Medicine, University of California, San Francisco, San Francisco, CA, United States.
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Źródło :
Pain [Pain] 2019 Aug; Vol. 160 (8), pp. 1876-1882.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Ganglia, Spinal/*metabolism
Hand-Arm Vibration Syndrome/*metabolism
Hyperalgesia/*metabolism
Interleukin-6/*metabolism
Kv1.4 Potassium Channel/*metabolism
Muscle, Skeletal/*metabolism
Musculoskeletal Pain/*metabolism
Animals ; Disease Models, Animal ; Gene Knockdown Techniques ; Hand-Arm Vibration Syndrome/genetics ; Interleukin-6/genetics ; Kv1.4 Potassium Channel/genetics ; Male ; Musculoskeletal Pain/genetics ; Rats ; Rats, Sprague-Dawley ; Vibration
Czasopismo naukowe
Tytuł :
Effect of traditional Chinese medicine injections on severe pneumonia: A protocol for systematic review and meta-analysis.
Autorzy :
Luo W; Department of Respiratory and Critical Care Medicine, Chongqing Jiangbei Hospital of Traditional Chinese Medicine.
Liu Y; Department of Dermatology, Chongqing Hospital of Traditional Chinese Medicine.
Zhang Q; Department of Oncology, Army Medical Center of PLA.
Zhong H; Department of Personnel Office, Chongqing Jiangbei Hospital of Traditional Chinese Medicine, Chongoing, China.
Deng J; Department of Respiratory and Critical Care Medicine, Chongqing Jiangbei Hospital of Traditional Chinese Medicine.
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Źródło :
Medicine [Medicine (Baltimore)] 2020 Sep 25; Vol. 99 (39), pp. e22012.
Typ publikacji :
Journal Article; Meta-Analysis; Systematic Review
MeSH Terms :
Medicine, Chinese Traditional/*methods
Pneumonia/*therapy
C-Reactive Protein/analysis ; Humans ; Injections ; Interleukin-6/blood ; Length of Stay ; Leukocyte Count ; Medicine, Chinese Traditional/adverse effects ; Pneumonia/mortality ; Procalcitonin/biosynthesis ; Randomized Controlled Trials as Topic ; Research Design ; Respiration, Artificial ; Tumor Necrosis Factor-alpha/blood
Czasopismo naukowe
Tytuł :
Acute necrotizing encephalopathy with SARS-CoV-2 RNA confirmed in cerebrospinal fluid.
Autorzy :
Virhammar J; From the Department of Neuroscience (J.V., E.K., S.J.), Neurology, Uppsala University, Uppsala, Sweden; Department of Surgical Sciences (D.F., J.W., A.G.), Radiology, Uppsala University, Uppsala, Sweden; Department of Surgical Sciences (R.F., H.D.P.D.O.-R.), Anaesthesia and Intensive Care, Uppsala University, Uppsala, Sweden; Department of Neuroscience (M.K.S., H.D.P.D.O.-R., E.R.), Neurosurgery, Uppsala University, Uppsala, Sweden; Department of Internal Medicine (M.K., J.L.), Nyköping Hospital, Nyköping, Sweden; Department of Radiology (J.F.), Nyköping Hospital, Nyköping, Sweden; Department of Neuroscience (J.L.C.), Psychiatry, Uppsala University, Uppsala, Sweden; Department of Medical Sciences (K.B.), Uppsala University, Uppsala, Sweden; Department of Chemistry-BMC (J.B.), Analytical Chemistry and Neurochemistry, Uppsala University, Uppsala, Sweden; Department of Psychiatry and Neurochemistry (H.Z.), Institute of Neuroscience & Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal; and Clinical Neurochemistry Laboratory (H.Z.), Sahlgrenska University Hospital, Mölndal, Sweden.
Kumlien E; From the Department of Neuroscience (J.V., E.K., S.J.), Neurology, Uppsala University, Uppsala, Sweden; Department of Surgical Sciences (D.F., J.W., A.G.), Radiology, Uppsala University, Uppsala, Sweden; Department of Surgical Sciences (R.F., H.D.P.D.O.-R.), Anaesthesia and Intensive Care, Uppsala University, Uppsala, Sweden; Department of Neuroscience (M.K.S., H.D.P.D.O.-R., E.R.), Neurosurgery, Uppsala University, Uppsala, Sweden; Department of Internal Medicine (M.K., J.L.), Nyköping Hospital, Nyköping, Sweden; Department of Radiology (J.F.), Nyköping Hospital, Nyköping, Sweden; Department of Neuroscience (J.L.C.), Psychiatry, Uppsala University, Uppsala, Sweden; Department of Medical Sciences (K.B.), Uppsala University, Uppsala, Sweden; Department of Chemistry-BMC (J.B.), Analytical Chemistry and Neurochemistry, Uppsala University, Uppsala, Sweden; Department of Psychiatry and Neurochemistry (H.Z.), Institute of Neuroscience & Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal; and Clinical Neurochemistry Laboratory (H.Z.), Sahlgrenska University Hospital, Mölndal, Sweden.
Fällmar D; From the Department of Neuroscience (J.V., E.K., S.J.), Neurology, Uppsala University, Uppsala, Sweden; Department of Surgical Sciences (D.F., J.W., A.G.), Radiology, Uppsala University, Uppsala, Sweden; Department of Surgical Sciences (R.F., H.D.P.D.O.-R.), Anaesthesia and Intensive Care, Uppsala University, Uppsala, Sweden; Department of Neuroscience (M.K.S., H.D.P.D.O.-R., E.R.), Neurosurgery, Uppsala University, Uppsala, Sweden; Department of Internal Medicine (M.K., J.L.), Nyköping Hospital, Nyköping, Sweden; Department of Radiology (J.F.), Nyköping Hospital, Nyköping, Sweden; Department of Neuroscience (J.L.C.), Psychiatry, Uppsala University, Uppsala, Sweden; Department of Medical Sciences (K.B.), Uppsala University, Uppsala, Sweden; Department of Chemistry-BMC (J.B.), Analytical Chemistry and Neurochemistry, Uppsala University, Uppsala, Sweden; Department of Psychiatry and Neurochemistry (H.Z.), Institute of Neuroscience & Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal; and Clinical Neurochemistry Laboratory (H.Z.), Sahlgrenska University Hospital, Mölndal, Sweden.
Frithiof R; From the Department of Neuroscience (J.V., E.K., S.J.), Neurology, Uppsala University, Uppsala, Sweden; Department of Surgical Sciences (D.F., J.W., A.G.), Radiology, Uppsala University, Uppsala, Sweden; Department of Surgical Sciences (R.F., H.D.P.D.O.-R.), Anaesthesia and Intensive Care, Uppsala University, Uppsala, Sweden; Department of Neuroscience (M.K.S., H.D.P.D.O.-R., E.R.), Neurosurgery, Uppsala University, Uppsala, Sweden; Department of Internal Medicine (M.K., J.L.), Nyköping Hospital, Nyköping, Sweden; Department of Radiology (J.F.), Nyköping Hospital, Nyköping, Sweden; Department of Neuroscience (J.L.C.), Psychiatry, Uppsala University, Uppsala, Sweden; Department of Medical Sciences (K.B.), Uppsala University, Uppsala, Sweden; Department of Chemistry-BMC (J.B.), Analytical Chemistry and Neurochemistry, Uppsala University, Uppsala, Sweden; Department of Psychiatry and Neurochemistry (H.Z.), Institute of Neuroscience & Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal; and Clinical Neurochemistry Laboratory (H.Z.), Sahlgrenska University Hospital, Mölndal, Sweden.
Jackmann S; From the Department of Neuroscience (J.V., E.K., S.J.), Neurology, Uppsala University, Uppsala, Sweden; Department of Surgical Sciences (D.F., J.W., A.G.), Radiology, Uppsala University, Uppsala, Sweden; Department of Surgical Sciences (R.F., H.D.P.D.O.-R.), Anaesthesia and Intensive Care, Uppsala University, Uppsala, Sweden; Department of Neuroscience (M.K.S., H.D.P.D.O.-R., E.R.), Neurosurgery, Uppsala University, Uppsala, Sweden; Department of Internal Medicine (M.K., J.L.), Nyköping Hospital, Nyköping, Sweden; Department of Radiology (J.F.), Nyköping Hospital, Nyköping, Sweden; Department of Neuroscience (J.L.C.), Psychiatry, Uppsala University, Uppsala, Sweden; Department of Medical Sciences (K.B.), Uppsala University, Uppsala, Sweden; Department of Chemistry-BMC (J.B.), Analytical Chemistry and Neurochemistry, Uppsala University, Uppsala, Sweden; Department of Psychiatry and Neurochemistry (H.Z.), Institute of Neuroscience & Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal; and Clinical Neurochemistry Laboratory (H.Z.), Sahlgrenska University Hospital, Mölndal, Sweden.
Sköld MK; From the Department of Neuroscience (J.V., E.K., S.J.), Neurology, Uppsala University, Uppsala, Sweden; Department of Surgical Sciences (D.F., J.W., A.G.), Radiology, Uppsala University, Uppsala, Sweden; Department of Surgical Sciences (R.F., H.D.P.D.O.-R.), Anaesthesia and Intensive Care, Uppsala University, Uppsala, Sweden; Department of Neuroscience (M.K.S., H.D.P.D.O.-R., E.R.), Neurosurgery, Uppsala University, Uppsala, Sweden; Department of Internal Medicine (M.K., J.L.), Nyköping Hospital, Nyköping, Sweden; Department of Radiology (J.F.), Nyköping Hospital, Nyköping, Sweden; Department of Neuroscience (J.L.C.), Psychiatry, Uppsala University, Uppsala, Sweden; Department of Medical Sciences (K.B.), Uppsala University, Uppsala, Sweden; Department of Chemistry-BMC (J.B.), Analytical Chemistry and Neurochemistry, Uppsala University, Uppsala, Sweden; Department of Psychiatry and Neurochemistry (H.Z.), Institute of Neuroscience & Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal; and Clinical Neurochemistry Laboratory (H.Z.), Sahlgrenska University Hospital, Mölndal, Sweden.
Kadir M; From the Department of Neuroscience (J.V., E.K., S.J.), Neurology, Uppsala University, Uppsala, Sweden; Department of Surgical Sciences (D.F., J.W., A.G.), Radiology, Uppsala University, Uppsala, Sweden; Department of Surgical Sciences (R.F., H.D.P.D.O.-R.), Anaesthesia and Intensive Care, Uppsala University, Uppsala, Sweden; Department of Neuroscience (M.K.S., H.D.P.D.O.-R., E.R.), Neurosurgery, Uppsala University, Uppsala, Sweden; Department of Internal Medicine (M.K., J.L.), Nyköping Hospital, Nyköping, Sweden; Department of Radiology (J.F.), Nyköping Hospital, Nyköping, Sweden; Department of Neuroscience (J.L.C.), Psychiatry, Uppsala University, Uppsala, Sweden; Department of Medical Sciences (K.B.), Uppsala University, Uppsala, Sweden; Department of Chemistry-BMC (J.B.), Analytical Chemistry and Neurochemistry, Uppsala University, Uppsala, Sweden; Department of Psychiatry and Neurochemistry (H.Z.), Institute of Neuroscience & Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal; and Clinical Neurochemistry Laboratory (H.Z.), Sahlgrenska University Hospital, Mölndal, Sweden.
Frick J; From the Department of Neuroscience (J.V., E.K., S.J.), Neurology, Uppsala University, Uppsala, Sweden; Department of Surgical Sciences (D.F., J.W., A.G.), Radiology, Uppsala University, Uppsala, Sweden; Department of Surgical Sciences (R.F., H.D.P.D.O.-R.), Anaesthesia and Intensive Care, Uppsala University, Uppsala, Sweden; Department of Neuroscience (M.K.S., H.D.P.D.O.-R., E.R.), Neurosurgery, Uppsala University, Uppsala, Sweden; Department of Internal Medicine (M.K., J.L.), Nyköping Hospital, Nyköping, Sweden; Department of Radiology (J.F.), Nyköping Hospital, Nyköping, Sweden; Department of Neuroscience (J.L.C.), Psychiatry, Uppsala University, Uppsala, Sweden; Department of Medical Sciences (K.B.), Uppsala University, Uppsala, Sweden; Department of Chemistry-BMC (J.B.), Analytical Chemistry and Neurochemistry, Uppsala University, Uppsala, Sweden; Department of Psychiatry and Neurochemistry (H.Z.), Institute of Neuroscience & Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal; and Clinical Neurochemistry Laboratory (H.Z.), Sahlgrenska University Hospital, Mölndal, Sweden.
Lindeberg J; From the Department of Neuroscience (J.V., E.K., S.J.), Neurology, Uppsala University, Uppsala, Sweden; Department of Surgical Sciences (D.F., J.W., A.G.), Radiology, Uppsala University, Uppsala, Sweden; Department of Surgical Sciences (R.F., H.D.P.D.O.-R.), Anaesthesia and Intensive Care, Uppsala University, Uppsala, Sweden; Department of Neuroscience (M.K.S., H.D.P.D.O.-R., E.R.), Neurosurgery, Uppsala University, Uppsala, Sweden; Department of Internal Medicine (M.K., J.L.), Nyköping Hospital, Nyköping, Sweden; Department of Radiology (J.F.), Nyköping Hospital, Nyköping, Sweden; Department of Neuroscience (J.L.C.), Psychiatry, Uppsala University, Uppsala, Sweden; Department of Medical Sciences (K.B.), Uppsala University, Uppsala, Sweden; Department of Chemistry-BMC (J.B.), Analytical Chemistry and Neurochemistry, Uppsala University, Uppsala, Sweden; Department of Psychiatry and Neurochemistry (H.Z.), Institute of Neuroscience & Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal; and Clinical Neurochemistry Laboratory (H.Z.), Sahlgrenska University Hospital, Mölndal, Sweden.
Olivero-Reinius H; From the Department of Neuroscience (J.V., E.K., S.J.), Neurology, Uppsala University, Uppsala, Sweden; Department of Surgical Sciences (D.F., J.W., A.G.), Radiology, Uppsala University, Uppsala, Sweden; Department of Surgical Sciences (R.F., H.D.P.D.O.-R.), Anaesthesia and Intensive Care, Uppsala University, Uppsala, Sweden; Department of Neuroscience (M.K.S., H.D.P.D.O.-R., E.R.), Neurosurgery, Uppsala University, Uppsala, Sweden; Department of Internal Medicine (M.K., J.L.), Nyköping Hospital, Nyköping, Sweden; Department of Radiology (J.F.), Nyköping Hospital, Nyköping, Sweden; Department of Neuroscience (J.L.C.), Psychiatry, Uppsala University, Uppsala, Sweden; Department of Medical Sciences (K.B.), Uppsala University, Uppsala, Sweden; Department of Chemistry-BMC (J.B.), Analytical Chemistry and Neurochemistry, Uppsala University, Uppsala, Sweden; Department of Psychiatry and Neurochemistry (H.Z.), Institute of Neuroscience & Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal; and Clinical Neurochemistry Laboratory (H.Z.), Sahlgrenska University Hospital, Mölndal, Sweden.
Ryttlefors M; From the Department of Neuroscience (J.V., E.K., S.J.), Neurology, Uppsala University, Uppsala, Sweden; Department of Surgical Sciences (D.F., J.W., A.G.), Radiology, Uppsala University, Uppsala, Sweden; Department of Surgical Sciences (R.F., H.D.P.D.O.-R.), Anaesthesia and Intensive Care, Uppsala University, Uppsala, Sweden; Department of Neuroscience (M.K.S., H.D.P.D.O.-R., E.R.), Neurosurgery, Uppsala University, Uppsala, Sweden; Department of Internal Medicine (M.K., J.L.), Nyköping Hospital, Nyköping, Sweden; Department of Radiology (J.F.), Nyköping Hospital, Nyköping, Sweden; Department of Neuroscience (J.L.C.), Psychiatry, Uppsala University, Uppsala, Sweden; Department of Medical Sciences (K.B.), Uppsala University, Uppsala, Sweden; Department of Chemistry-BMC (J.B.), Analytical Chemistry and Neurochemistry, Uppsala University, Uppsala, Sweden; Department of Psychiatry and Neurochemistry (H.Z.), Institute of Neuroscience & Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal; and Clinical Neurochemistry Laboratory (H.Z.), Sahlgrenska University Hospital, Mölndal, Sweden.
Cunningham JL; From the Department of Neuroscience (J.V., E.K., S.J.), Neurology, Uppsala University, Uppsala, Sweden; Department of Surgical Sciences (D.F., J.W., A.G.), Radiology, Uppsala University, Uppsala, Sweden; Department of Surgical Sciences (R.F., H.D.P.D.O.-R.), Anaesthesia and Intensive Care, Uppsala University, Uppsala, Sweden; Department of Neuroscience (M.K.S., H.D.P.D.O.-R., E.R.), Neurosurgery, Uppsala University, Uppsala, Sweden; Department of Internal Medicine (M.K., J.L.), Nyköping Hospital, Nyköping, Sweden; Department of Radiology (J.F.), Nyköping Hospital, Nyköping, Sweden; Department of Neuroscience (J.L.C.), Psychiatry, Uppsala University, Uppsala, Sweden; Department of Medical Sciences (K.B.), Uppsala University, Uppsala, Sweden; Department of Chemistry-BMC (J.B.), Analytical Chemistry and Neurochemistry, Uppsala University, Uppsala, Sweden; Department of Psychiatry and Neurochemistry (H.Z.), Institute of Neuroscience & Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal; and Clinical Neurochemistry Laboratory (H.Z.), Sahlgrenska University Hospital, Mölndal, Sweden.
Wikström J; From the Department of Neuroscience (J.V., E.K., S.J.), Neurology, Uppsala University, Uppsala, Sweden; Department of Surgical Sciences (D.F., J.W., A.G.), Radiology, Uppsala University, Uppsala, Sweden; Department of Surgical Sciences (R.F., H.D.P.D.O.-R.), Anaesthesia and Intensive Care, Uppsala University, Uppsala, Sweden; Department of Neuroscience (M.K.S., H.D.P.D.O.-R., E.R.), Neurosurgery, Uppsala University, Uppsala, Sweden; Department of Internal Medicine (M.K., J.L.), Nyköping Hospital, Nyköping, Sweden; Department of Radiology (J.F.), Nyköping Hospital, Nyköping, Sweden; Department of Neuroscience (J.L.C.), Psychiatry, Uppsala University, Uppsala, Sweden; Department of Medical Sciences (K.B.), Uppsala University, Uppsala, Sweden; Department of Chemistry-BMC (J.B.), Analytical Chemistry and Neurochemistry, Uppsala University, Uppsala, Sweden; Department of Psychiatry and Neurochemistry (H.Z.), Institute of Neuroscience & Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal; and Clinical Neurochemistry Laboratory (H.Z.), Sahlgrenska University Hospital, Mölndal, Sweden.
Grabowska A; From the Department of Neuroscience (J.V., E.K., S.J.), Neurology, Uppsala University, Uppsala, Sweden; Department of Surgical Sciences (D.F., J.W., A.G.), Radiology, Uppsala University, Uppsala, Sweden; Department of Surgical Sciences (R.F., H.D.P.D.O.-R.), Anaesthesia and Intensive Care, Uppsala University, Uppsala, Sweden; Department of Neuroscience (M.K.S., H.D.P.D.O.-R., E.R.), Neurosurgery, Uppsala University, Uppsala, Sweden; Department of Internal Medicine (M.K., J.L.), Nyköping Hospital, Nyköping, Sweden; Department of Radiology (J.F.), Nyköping Hospital, Nyköping, Sweden; Department of Neuroscience (J.L.C.), Psychiatry, Uppsala University, Uppsala, Sweden; Department of Medical Sciences (K.B.), Uppsala University, Uppsala, Sweden; Department of Chemistry-BMC (J.B.), Analytical Chemistry and Neurochemistry, Uppsala University, Uppsala, Sweden; Department of Psychiatry and Neurochemistry (H.Z.), Institute of Neuroscience & Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal; and Clinical Neurochemistry Laboratory (H.Z.), Sahlgrenska University Hospital, Mölndal, Sweden.
Bondeson K; From the Department of Neuroscience (J.V., E.K., S.J.), Neurology, Uppsala University, Uppsala, Sweden; Department of Surgical Sciences (D.F., J.W., A.G.), Radiology, Uppsala University, Uppsala, Sweden; Department of Surgical Sciences (R.F., H.D.P.D.O.-R.), Anaesthesia and Intensive Care, Uppsala University, Uppsala, Sweden; Department of Neuroscience (M.K.S., H.D.P.D.O.-R., E.R.), Neurosurgery, Uppsala University, Uppsala, Sweden; Department of Internal Medicine (M.K., J.L.), Nyköping Hospital, Nyköping, Sweden; Department of Radiology (J.F.), Nyköping Hospital, Nyköping, Sweden; Department of Neuroscience (J.L.C.), Psychiatry, Uppsala University, Uppsala, Sweden; Department of Medical Sciences (K.B.), Uppsala University, Uppsala, Sweden; Department of Chemistry-BMC (J.B.), Analytical Chemistry and Neurochemistry, Uppsala University, Uppsala, Sweden; Department of Psychiatry and Neurochemistry (H.Z.), Institute of Neuroscience & Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal; and Clinical Neurochemistry Laboratory (H.Z.), Sahlgrenska University Hospital, Mölndal, Sweden.
Bergquist J; From the Department of Neuroscience (J.V., E.K., S.J.), Neurology, Uppsala University, Uppsala, Sweden; Department of Surgical Sciences (D.F., J.W., A.G.), Radiology, Uppsala University, Uppsala, Sweden; Department of Surgical Sciences (R.F., H.D.P.D.O.-R.), Anaesthesia and Intensive Care, Uppsala University, Uppsala, Sweden; Department of Neuroscience (M.K.S., H.D.P.D.O.-R., E.R.), Neurosurgery, Uppsala University, Uppsala, Sweden; Department of Internal Medicine (M.K., J.L.), Nyköping Hospital, Nyköping, Sweden; Department of Radiology (J.F.), Nyköping Hospital, Nyköping, Sweden; Department of Neuroscience (J.L.C.), Psychiatry, Uppsala University, Uppsala, Sweden; Department of Medical Sciences (K.B.), Uppsala University, Uppsala, Sweden; Department of Chemistry-BMC (J.B.), Analytical Chemistry and Neurochemistry, Uppsala University, Uppsala, Sweden; Department of Psychiatry and Neurochemistry (H.Z.), Institute of Neuroscience & Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal; and Clinical Neurochemistry Laboratory (H.Z.), Sahlgrenska University Hospital, Mölndal, Sweden.
Zetterberg H; From the Department of Neuroscience (J.V., E.K., S.J.), Neurology, Uppsala University, Uppsala, Sweden; Department of Surgical Sciences (D.F., J.W., A.G.), Radiology, Uppsala University, Uppsala, Sweden; Department of Surgical Sciences (R.F., H.D.P.D.O.-R.), Anaesthesia and Intensive Care, Uppsala University, Uppsala, Sweden; Department of Neuroscience (M.K.S., H.D.P.D.O.-R., E.R.), Neurosurgery, Uppsala University, Uppsala, Sweden; Department of Internal Medicine (M.K., J.L.), Nyköping Hospital, Nyköping, Sweden; Department of Radiology (J.F.), Nyköping Hospital, Nyköping, Sweden; Department of Neuroscience (J.L.C.), Psychiatry, Uppsala University, Uppsala, Sweden; Department of Medical Sciences (K.B.), Uppsala University, Uppsala, Sweden; Department of Chemistry-BMC (J.B.), Analytical Chemistry and Neurochemistry, Uppsala University, Uppsala, Sweden; Department of Psychiatry and Neurochemistry (H.Z.), Institute of Neuroscience & Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal; and Clinical Neurochemistry Laboratory (H.Z.), Sahlgrenska University Hospital, Mölndal, Sweden.
Rostami E; From the Department of Neuroscience (J.V., E.K., S.J.), Neurology, Uppsala University, Uppsala, Sweden; Department of Surgical Sciences (D.F., J.W., A.G.), Radiology, Uppsala University, Uppsala, Sweden; Department of Surgical Sciences (R.F., H.D.P.D.O.-R.), Anaesthesia and Intensive Care, Uppsala University, Uppsala, Sweden; Department of Neuroscience (M.K.S., H.D.P.D.O.-R., E.R.), Neurosurgery, Uppsala University, Uppsala, Sweden; Department of Internal Medicine (M.K., J.L.), Nyköping Hospital, Nyköping, Sweden; Department of Radiology (J.F.), Nyköping Hospital, Nyköping, Sweden; Department of Neuroscience (J.L.C.), Psychiatry, Uppsala University, Uppsala, Sweden; Department of Medical Sciences (K.B.), Uppsala University, Uppsala, Sweden; Department of Chemistry-BMC (J.B.), Analytical Chemistry and Neurochemistry, Uppsala University, Uppsala, Sweden; Department of Psychiatry and Neurochemistry (H.Z.), Institute of Neuroscience & Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal; and Clinical Neurochemistry Laboratory (H.Z.), Sahlgrenska University Hospital, Mölndal, Sweden. .
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Źródło :
Neurology [Neurology] 2020 Sep 08; Vol. 95 (10), pp. 445-449. Date of Electronic Publication: 2020 Jun 25.
Typ publikacji :
Case Reports; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Brain/*diagnostic imaging
Coronavirus Infections/*cerebrospinal fluid
Leukoencephalitis, Acute Hemorrhagic/*cerebrospinal fluid
Pneumonia, Viral/*cerebrospinal fluid
RNA, Viral/*cerebrospinal fluid
Acyclovir/therapeutic use ; Antiviral Agents/therapeutic use ; Betacoronavirus/genetics ; Coronavirus Infections/diagnostic imaging ; Coronavirus Infections/physiopathology ; Coronavirus Infections/therapy ; Female ; Glial Fibrillary Acidic Protein/cerebrospinal fluid ; Humans ; Immunoglobulins, Intravenous/therapeutic use ; Immunologic Factors/therapeutic use ; Interleukin-6/cerebrospinal fluid ; Leukoencephalitis, Acute Hemorrhagic/diagnostic imaging ; Leukoencephalitis, Acute Hemorrhagic/physiopathology ; Leukoencephalitis, Acute Hemorrhagic/therapy ; Magnetic Resonance Imaging ; Middle Aged ; Neurofilament Proteins/cerebrospinal fluid ; Pandemics ; Plasma Exchange ; Pneumonia, Viral/diagnostic imaging ; Pneumonia, Viral/physiopathology ; Pneumonia, Viral/therapy ; Real-Time Polymerase Chain Reaction ; Tomography, X-Ray Computed ; Viral Tropism ; tau Proteins/cerebrospinal fluid
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Prospective Translational Study Investigating Molecular PrEdictors of Resistance to First-Line PazopanIb in Metastatic reNal CEll Carcinoma (PIPELINE Study).
Autorzy :
Sepe P; Department of Medical Oncology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan.
Martinetti A; Department of Medical Oncology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan.
Mennitto A; Department of Medical Oncology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan.
Verzoni E; Department of Medical Oncology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan.
Claps M; Department of Medical Oncology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan.
Raimondi A; Department of Medical Oncology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan.
Sottotetti E; Department of Medical Oncology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan.
Grassi P; Department of Medical Oncology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan.
Guadalupi V; Department of Medical Oncology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan.
Stellato M; Department of Medical Oncology, Campus Bio-Medico University of Rome, Rome.
Zattarin E; Department of Medical Oncology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan.
Di Maio M; Department of Oncology, Ordine Mauriziano Hospital, University of Turin, Turin, Italy.
Procopio G; Department of Medical Oncology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan.
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Źródło :
American journal of clinical oncology [Am J Clin Oncol] 2020 Sep; Vol. 43 (9), pp. 621-627.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Drug Resistance, Neoplasm*
Antineoplastic Agents/*therapeutic use
Carcinoma, Renal Cell/*drug therapy
Kidney Neoplasms/*drug therapy
Pyrimidines/*therapeutic use
Sulfonamides/*therapeutic use
Aged ; Angiogenesis Inhibitors/therapeutic use ; Carcinoma, Renal Cell/blood ; Carcinoma, Renal Cell/secondary ; Chemokine CXCL12/blood ; Disease Progression ; E-Selectin/blood ; Female ; Hepatocyte Growth Factor/blood ; Humans ; Interleukin-6/blood ; Interleukin-8/blood ; Kidney Neoplasms/blood ; Kidney Neoplasms/pathology ; Male ; Middle Aged ; Osteopontin/blood ; Progression-Free Survival ; Prospective Studies ; Response Evaluation Criteria in Solid Tumors ; Survival Rate ; Translational Medical Research ; Vascular Endothelial Growth Factor A/blood
Czasopismo naukowe
Tytuł :
IL-6 (Interleukin 6) Blockade and Heart Rate Corrected QT Interval Prolongation in COVID-19.
Autorzy :
Lazzerini PE; Department of Medical Sciences, Surgery and Neurosciences, University of Siena, Italy (P.E.L., F.L.-P., P.L.C.).
Laghi-Pasini F; Department of Medical Sciences, Surgery and Neurosciences, University of Siena, Italy (P.E.L., F.L.-P., P.L.C.).
Acampa M; Stroke Unit, University Hospital of Siena, Italy (M.A.).
Boutjdir M; VA New York Harbor Healthcare System, SUNY Downstate Medical Center (M.B.).; NYU School of Medicine, New York, NY (M.B.).
Leopoldo Capecchi P; Department of Medical Sciences, Surgery and Neurosciences, University of Siena, Italy (P.E.L., F.L.-P., P.L.C.).
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Źródło :
Circulation. Arrhythmia and electrophysiology [Circ Arrhythm Electrophysiol] 2020 Sep; Vol. 13 (9), pp. e008791. Date of Electronic Publication: 2020 Jul 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Antiviral Agents/*adverse effects
Coronavirus Infections/*drug therapy
Cross Infection/*prevention & control
Electrocardiography/*methods
Interleukin-6/*metabolism
Long QT Syndrome/*chemically induced
Pneumonia, Viral/*drug therapy
Aged ; Antibodies, Monoclonal, Humanized/administration & dosage ; Antibodies, Monoclonal, Humanized/adverse effects ; Antiviral Agents/administration & dosage ; Coronavirus Infections/diagnosis ; Electrocardiography, Ambulatory/methods ; Female ; Humans ; Italy ; Long QT Syndrome/diagnosis ; Long QT Syndrome/epidemiology ; Male ; Middle Aged ; Pandemics ; Patient Safety ; Pneumonia, Viral/diagnosis
SCR Disease Name :
COVID-19
Czasopismo naukowe

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