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Tytuł:
Autocrine Regulation of Interleukin-6 via the Activation of STAT3 and Akt in Cardiac Myxoma Cells.
Autorzy:
Jougasaki M; Institute for Clinical Research, NHO Kagoshima Medical Center, Kagoshima 892-0853, Japan.
Takenoshita Y; Institute for Clinical Research, NHO Kagoshima Medical Center, Kagoshima 892-0853, Japan.
Umebashi K; Institute for Clinical Research, NHO Kagoshima Medical Center, Kagoshima 892-0853, Japan.
Yamamoto M; Institute for Clinical Research, NHO Kagoshima Medical Center, Kagoshima 892-0853, Japan.
Sudou K; Institute for Clinical Research, NHO Kagoshima Medical Center, Kagoshima 892-0853, Japan.
Nakashima H; Institute for Clinical Research, NHO Kagoshima Medical Center, Kagoshima 892-0853, Japan.
Sonoda M; Institute for Clinical Research, NHO Kagoshima Medical Center, Kagoshima 892-0853, Japan.
Kinjo T; Institute for Clinical Research, NHO Kagoshima Medical Center, Kagoshima 892-0853, Japan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 13; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 13.
Typ publikacji:
Journal Article
MeSH Terms:
Interleukin-6*/metabolism
Myxoma*/metabolism
Humans ; Cells, Cultured ; Proto-Oncogene Proteins c-akt/metabolism ; Receptors, Interleukin-6/metabolism ; Signal Transduction ; STAT3 Transcription Factor/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
An epithelial gene signature of trans-IL-6 signaling defines a subgroup of type 2-low asthma.
Autorzy:
El-Husseini ZW; Department of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children's Hospital, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD (GRIAC), Groningen, The Netherlands.; Department of Molecular Pharmacology, Faculty of Science and Engineering, Groningen Research Institute of Pharmacy, University of Groningen, 9713 AV, Groningen, The Netherlands.
Khalenkow D; Department of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children's Hospital, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD (GRIAC), Groningen, The Netherlands.
Lan A; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD (GRIAC), Groningen, The Netherlands.; Department of Molecular Pharmacology, Faculty of Science and Engineering, Groningen Research Institute of Pharmacy, University of Groningen, 9713 AV, Groningen, The Netherlands.
van der Molen T; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD (GRIAC), Groningen, The Netherlands.
Brightling C; Department of Infection, Immunity and Inflammation, Institute for Lung Health, University of Leicester, Leicester, UK.
Papi A; Department of Respiratory Medicine, University of Ferrara, Ferrara, Italy.
Rabe KF; Department of Medicine, Christian Albrechts University Kiel, Kiel and Lungen Clinic Grosshansdorf (Members of the German Center for Lung Research (DZL)), Grosshansdorf, Germany.
Siddiqui S; National Heart and Lung Institute, Imperial College and Imperial NIHR Biomedical Research Centre, London, UK.
Singh D; Medicines Evaluation Unit, Manchester University NHS Foundation Hospital Trust, University of Manchester, Manchester, UK.
Kraft M; Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, USA.
Beghe B; University of Modena and Reggio Emilia, AOU of Modena, Modena, Italy.
van den Berge M; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD (GRIAC), Groningen, The Netherlands.; Department of Pulmonary Diseases, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
van Gosliga D; Department of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children's Hospital, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD (GRIAC), Groningen, The Netherlands.; Department of Pathology and Medical Biology, Experimental Pulmonary and Inflammatory Research (EXPIRE), University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands.
Nawijn MC; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD (GRIAC), Groningen, The Netherlands.; Department of Pathology and Medical Biology, Experimental Pulmonary and Inflammatory Research (EXPIRE), University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands.
Rose-John S; Biochemical Institute, University of Kiel, Kiel, Germany.
Koppelman GH; Department of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children's Hospital, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD (GRIAC), Groningen, The Netherlands.
Gosens R; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD (GRIAC), Groningen, The Netherlands. .; Department of Molecular Pharmacology, Faculty of Science and Engineering, Groningen Research Institute of Pharmacy, University of Groningen, 9713 AV, Groningen, The Netherlands. .
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Źródło:
Respiratory research [Respir Res] 2023 Dec 07; Vol. 24 (1), pp. 308. Date of Electronic Publication: 2023 Dec 07.
Typ publikacji:
Journal Article
MeSH Terms:
Asthma*/diagnosis
Asthma*/drug therapy
Asthma*/genetics
Interleukin-6*/metabolism
Humans ; Cytokine Receptor gp130/genetics ; Cytokine Receptor gp130/metabolism ; Inflammation ; Receptors, Interleukin-6/genetics ; Receptors, Interleukin-6/metabolism ; Signal Transduction
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Nonspecific Inhibition of IL6 Family Cytokine Signalling by Soluble gp130.
Autorzy:
Widjaja AA; Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School, 8 College Road, Singapore 169857, Singapore.
Cook SA; Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School, 8 College Road, Singapore 169857, Singapore.; National Heart Centre Singapore, National Heart Research Institute Singapore, Singapore 169609, Singapore.; MRC-London Institute of Medical Sciences, Hammersmith Hospital Campus, London W6 8RF, UK.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 23; Vol. 25 (3). Date of Electronic Publication: 2024 Jan 23.
Typ publikacji:
Journal Article
MeSH Terms:
Cytokines*/pharmacology
Interleukin-6*/metabolism
Mice ; Humans ; Animals ; Cytokine Receptor gp130/metabolism ; Signal Transduction ; Receptors, Interleukin-6
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Associations between serum estradiol and IL-6/sIL-6R/sgp130 complex in female patients with major depressive disorder.
Autorzy:
Sun T; Department of Clinical Laboratory, Renmin Hospital of Wuhan University, Zhangzhidong Road, Wuchang District, Wuhan, 430060, Hubei, China.
Chen Q; Department of Clinical Laboratory, Renmin Hospital of Wuhan University, Zhangzhidong Road, Wuchang District, Wuhan, 430060, Hubei, China.
Mei J; Department of Clinical Laboratory, Renmin Hospital of Wuhan University, Zhangzhidong Road, Wuchang District, Wuhan, 430060, Hubei, China.
Li Y; Department of Clinical Laboratory, Renmin Hospital of Wuhan University, Zhangzhidong Road, Wuchang District, Wuhan, 430060, Hubei, China. .
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Źródło:
BMC psychiatry [BMC Psychiatry] 2023 Oct 12; Vol. 23 (1), pp. 742. Date of Electronic Publication: 2023 Oct 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Depressive Disorder, Major*/diagnosis
Receptors, Interleukin-6*
Female ; Humans ; Biomarkers ; Cytokine Receptor gp130 ; Estradiol ; Interleukin-6
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Association of Polymorphisms of IL-6 Pathway Genes (IL6, IL6R and IL6ST) with COVID-19 Severity in an Amazonian Population.
Autorzy:
Rodrigues FBB; Laboratório de Genética de Doenças Complexas, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 58255-000, Brazil.; Programa de Pós-Graduação em Biologia de Agentes Infecciosos e Parasitários, Universidade Federal do Pará, Belém 58255-000, Brazil.
da Silva R; Laboratório de Genética de Doenças Complexas, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 58255-000, Brazil.; Programa de Pós-Graduação em Biologia de Agentes Infecciosos e Parasitários, Universidade Federal do Pará, Belém 58255-000, Brazil.
Santos EFD; Laboratório de Genética de Doenças Complexas, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 58255-000, Brazil.; Programa de Pós-Graduação em Biologia de Agentes Infecciosos e Parasitários, Universidade Federal do Pará, Belém 58255-000, Brazil.
de Brito MTFM; Laboratório de Genética de Doenças Complexas, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 58255-000, Brazil.
da Silva ALS; Laboratório de Genética de Doenças Complexas, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 58255-000, Brazil.
de Meira Leite M; Laboratório de Genética de Doenças Complexas, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 58255-000, Brazil.
Póvoa da Costa F; Laboratório de Genética de Doenças Complexas, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 58255-000, Brazil.; Programa de Pós-Graduação em Biologia de Agentes Infecciosos e Parasitários, Universidade Federal do Pará, Belém 58255-000, Brazil.
de Nazaré do Socorro de Almeida Viana M; Laboratório de Genética de Doenças Complexas, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 58255-000, Brazil.; Programa de Pós-Graduação em Biologia de Agentes Infecciosos e Parasitários, Universidade Federal do Pará, Belém 58255-000, Brazil.
de Sarges KML; Laboratório de Genética de Doenças Complexas, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 58255-000, Brazil.; Programa de Pós-Graduação em Biologia de Agentes Infecciosos e Parasitários, Universidade Federal do Pará, Belém 58255-000, Brazil.
Cantanhede MHD; Laboratório de Genética de Doenças Complexas, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 58255-000, Brazil.; Programa de Pós-Graduação em Biologia de Agentes Infecciosos e Parasitários, Universidade Federal do Pará, Belém 58255-000, Brazil.
Veríssimo AOL; Hospital Adventista de Belém, Belém 66093-681, Brazil.
Carvalho MDS; Hospital Adventista de Belém, Belém 66093-681, Brazil.
Henriques DF; Seção de Arbovirologia e Febres Hemorrágicas, Instituto Evandro Chagas, Secretaria de Vigilância em Saúde, Ministério da Saúde do Brasil, Ananindeua 67000-000, Brazil.
Silva CPD; Seção de Arbovirologia e Febres Hemorrágicas, Instituto Evandro Chagas, Secretaria de Vigilância em Saúde, Ministério da Saúde do Brasil, Ananindeua 67000-000, Brazil.
Costa IB; Laboratório de Imunologia, Seção de Virologia, Instituto Evandro Chagas, Secretaria de Vigilância em Saúde, Ministério da Saúde do Brasil, Ananindeua 67000-000, Brazil.
Nunes JAL; Laboratório de Imunologia, Seção de Virologia, Instituto Evandro Chagas, Secretaria de Vigilância em Saúde, Ministério da Saúde do Brasil, Ananindeua 67000-000, Brazil.
Costa IB; Laboratório de Imunologia, Seção de Virologia, Instituto Evandro Chagas, Secretaria de Vigilância em Saúde, Ministério da Saúde do Brasil, Ananindeua 67000-000, Brazil.
Viana GMR; Laboratório de Pesquisas Básicas em Malária, Seção de Parasitologia, Instituto Evandro Chagas, secretaria de Vigilância em Saúde, Ministério da Saúde do Brasil, Ananindeua 67000-000, Brazil.
Queiroz MAF; Laboratório de Virologia, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 58255-000, Brazil.
Lima SS; Laboratório de Virologia, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 58255-000, Brazil.
Lopes JDC; Programa de Pós-Graduação em Biologia de Agentes Infecciosos e Parasitários, Universidade Federal do Pará, Belém 58255-000, Brazil.; Laboratório de Virologia, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 58255-000, Brazil.
Torres MKDS; Programa de Pós-Graduação em Biologia de Agentes Infecciosos e Parasitários, Universidade Federal do Pará, Belém 58255-000, Brazil.; Laboratório de Virologia, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 58255-000, Brazil.
Vallinoto IMVC; Programa de Pós-Graduação em Biologia de Agentes Infecciosos e Parasitários, Universidade Federal do Pará, Belém 58255-000, Brazil.; Laboratório de Virologia, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 58255-000, Brazil.
Bichara CDA; Programa de Pós-Graduação em Biologia de Agentes Infecciosos e Parasitários, Universidade Federal do Pará, Belém 58255-000, Brazil.; Laboratório de Virologia, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 58255-000, Brazil.
Vallinoto ACR; Laboratório de Virologia, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 58255-000, Brazil.
Santos EJMD; Laboratório de Genética de Doenças Complexas, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 58255-000, Brazil.
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Źródło:
Viruses [Viruses] 2023 May 19; Vol. 15 (5). Date of Electronic Publication: 2023 May 19.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Interleukin-6*/genetics
COVID-19*/genetics
Humans ; Cross-Sectional Studies ; Receptors, Interleukin-6/genetics ; Genotype ; Polymorphism, Single Nucleotide ; Genetic Predisposition to Disease ; Cytokine Receptor gp130/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Constitutive knockout of interleukin-6 ameliorates memory deficits and entorhinal astrocytosis in the MRL/lpr mouse model of neuropsychiatric lupus.
Autorzy:
Reynolds J; Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York, NY, USA.
Huang M; Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York, NY, USA.
Li Y; University of Houston, Houston, TX, USA.
Meineck M; University Medical Center of the Johannes Gutenberg University, University of Mainz, Mainz, Germany.
Moeckel T; University Medical Center of the Johannes Gutenberg University, University of Mainz, Mainz, Germany.
Weinmann-Menke J; University Medical Center of the Johannes Gutenberg University, University of Mainz, Mainz, Germany.
Mohan C; University of Houston, Houston, TX, USA.
Schwarting A; University Medical Center of the Johannes Gutenberg University, University of Mainz, Mainz, Germany.
Putterman C; Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York, NY, USA. .; Azrieli Faculty of Medicine, Bar-Ilan University, Zefat, Israel. .
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Źródło:
Journal of neuroinflammation [J Neuroinflammation] 2024 Apr 10; Vol. 21 (1), pp. 89. Date of Electronic Publication: 2024 Apr 10.
Typ publikacji:
Journal Article
MeSH Terms:
Interleukin-6*/genetics
Lupus Erythematosus, Systemic*
Lupus Vasculitis, Central Nervous System*
Animals ; Mice ; Depression ; Gliosis ; Memory Disorders/genetics ; Mice, Inbred MRL lpr
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Circadian gene Rev-erbα influenced by sleep conduces to pregnancy by promoting endometrial decidualization via IL-6-PR-C/EBPβ axis.
Autorzy:
Cui L; NHC Key Lab of Reproduction Regulation (Shanghai Institute of Planned Parenthood Research), Hospital of Obstetrics and Gynecology, Fudan University Shanghai Medical College, Shanghai, 200090, China.; Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Shanghai, 200090, China.
Xu F; NHC Key Lab of Reproduction Regulation (Shanghai Institute of Planned Parenthood Research), Hospital of Obstetrics and Gynecology, Fudan University Shanghai Medical College, Shanghai, 200090, China.; Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Shanghai, 200090, China.
Xu C; NHC Key Lab of Reproduction Regulation (Shanghai Institute of Planned Parenthood Research), Hospital of Obstetrics and Gynecology, Fudan University Shanghai Medical College, Shanghai, 200090, China.; Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Shanghai, 200090, China.
Ding Y; NHC Key Lab of Reproduction Regulation (Shanghai Institute of Planned Parenthood Research), Hospital of Obstetrics and Gynecology, Fudan University Shanghai Medical College, Shanghai, 200090, China.; Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Shanghai, 200090, China.
Wang S; NHC Key Lab of Reproduction Regulation (Shanghai Institute of Planned Parenthood Research), Hospital of Obstetrics and Gynecology, Fudan University Shanghai Medical College, Shanghai, 200090, China. .; Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Shanghai, 200090, China. .; Laboratory for Reproductive Immunology, Hospital of Obstetrics and Gynecology, Fudan University Shanghai Medical College, ZhaoZhou Road 413, Shanghai, 200011, China. .
Du M; NHC Key Lab of Reproduction Regulation (Shanghai Institute of Planned Parenthood Research), Hospital of Obstetrics and Gynecology, Fudan University Shanghai Medical College, Shanghai, 200090, China. .; Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Shanghai, 200090, China. .; Laboratory for Reproductive Immunology, Hospital of Obstetrics and Gynecology, Fudan University Shanghai Medical College, ZhaoZhou Road 413, Shanghai, 200011, China. .; State Key Laboratory of Quality Research in Chinese Medicine and School of Pharmacy, Macau University of Science and Technology, Macau, SAR, China. .; Department of Obstetrics and Gynecology, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Guangzhou, 510180, China. .
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Źródło:
Journal of biomedical science [J Biomed Sci] 2022 Nov 24; Vol. 29 (1), pp. 101. Date of Electronic Publication: 2022 Nov 24.
Typ publikacji:
Journal Article
MeSH Terms:
Interleukin-6*/genetics
Nuclear Receptor Subfamily 1, Group D, Member 1*/genetics
Nuclear Receptor Subfamily 1, Group D, Member 1*/metabolism
Animals ; Female ; Mice ; Pregnancy ; Circadian Rhythm/genetics ; Receptors, Interleukin-6 ; Sleep ; CCAAT-Enhancer-Binding Protein-beta/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Interleukin-6 signaling requires EHD1-mediated alteration of membrane rafts.
Autorzy:
Woo JH; Inflamm-aging Translational Research Center, Ajou University School of Medicine, Suwon, Korea.
Park SJ; Inflamm-aging Translational Research Center, Ajou University School of Medicine, Suwon, Korea.
Park SM; Department of Pharmacology, Ajou University School of Medicine, Suwon, Korea.; Center for Convergence Research of Neurological Disorders, Ajou University School of Medicine, Suwon, Korea.
Joe EH; Department of Pharmacology, Ajou University School of Medicine, Suwon, Korea.; Center for Convergence Research of Neurological Disorders, Ajou University School of Medicine, Suwon, Korea.
Jou I; Inflamm-aging Translational Research Center, Ajou University School of Medicine, Suwon, Korea.; Department of Pharmacology, Ajou University School of Medicine, Suwon, Korea.
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Źródło:
The FEBS journal [FEBS J] 2022 Oct; Vol. 289 (19), pp. 5914-5932. Date of Electronic Publication: 2022 Apr 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cholera Toxin*/metabolism
Interleukin-6*/genetics
Interleukin-6*/metabolism
Cholesterol/metabolism ; Cytokine Receptor gp130/genetics ; Cytokine Receptor gp130/metabolism ; Membrane Microdomains/metabolism ; Membrane Proteins/metabolism ; Receptors, Interleukin-6/genetics ; Receptors, Interleukin-6/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Immunization with a peptide mimicking lipoteichoic acid induces memory B cells in BALB/c mice.
Autorzy:
Yi XY; Department of Immunology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, Guangdong, P.R. China.; Department of Clinical Laboratory, The First People's Hospital of Wuhu, Wuhu, Anhui, P.R. China.
Hou XR; Department of Immunology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, Guangdong, P.R. China.
Huang ZX; Department of Immunology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, Guangdong, P.R. China.; Guangdong Provincial Engineering Research Center of Molecular Imaging, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, Guangdong, P.R. China.
Zhu P; Department of Immunology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, Guangdong, P.R. China.
Liu BY; Department of Immunology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, Guangdong, P.R. China. .
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Źródło:
BMC infectious diseases [BMC Infect Dis] 2024 Apr 02; Vol. 24 (1), pp. 371. Date of Electronic Publication: 2024 Apr 02.
Typ publikacji:
Journal Article
MeSH Terms:
Memory B Cells*
Interleukin-6*
Lipopolysaccharides*
Teichoic Acids*
Mice ; Animals ; Mice, Inbred BALB C ; Staphylococcus aureus ; Immunization ; Vaccination ; Peptides
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The effect of Dendrobium officinale extract in inhibiting the senescence of H 2 O 2 -induced fibroblasts based on the senescence-associated secretory phenotype.
Autorzy:
Li L; Shanghai Jahwa United Co., Ltd., Shanghai, China.
Zhu L; Shanghai Jahwa United Co., Ltd., Shanghai, China.
Chen M; Shanghai Jahwa United Co., Ltd., Shanghai, China.
Zhao Y; Shanghai Jahwa United Co., Ltd., Shanghai, China.
Jia H; Shanghai Jahwa United Co., Ltd., Shanghai, China.
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Źródło:
Journal of cosmetic dermatology [J Cosmet Dermatol] 2024 Apr; Vol. 23 (4), pp. 1360-1364. Date of Electronic Publication: 2023 Dec 06.
Typ publikacji:
Journal Article
MeSH Terms:
Interleukin-6*
Dendrobium*
Humans ; Senescence-Associated Secretory Phenotype ; Cellular Senescence ; Matrix Metalloproteinase 1 ; Hydrogen Peroxide/pharmacology ; Fibroblasts
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The mRNA-Binding Protein KSRP Limits the Inflammatory Response of Macrophages.
Autorzy:
Bolduan V; Department of Dermatology, University Medical Center, Langenbeckstr. 1, 55131 Mainz, Germany.
Palzer KA; Department of Pharmacology, University Medical Center, Langenbeckstr. 1, 55131 Mainz, Germany.
Hieber C; Department of Dermatology, University Medical Center, Langenbeckstr. 1, 55131 Mainz, Germany.
Schunke J; Department of Dermatology, University Medical Center, Langenbeckstr. 1, 55131 Mainz, Germany.
Fichter M; Department of Dermatology, University Medical Center, Langenbeckstr. 1, 55131 Mainz, Germany.; Max Planck Institute for Polymer Research, Ackermannweg 10, 55128 Mainz, Germany.
Schneider P; Department of Dermatology, University Medical Center, Langenbeckstr. 1, 55131 Mainz, Germany.
Grabbe S; Department of Dermatology, University Medical Center, Langenbeckstr. 1, 55131 Mainz, Germany.
Pautz A; Department of Pharmacology, University Medical Center, Langenbeckstr. 1, 55131 Mainz, Germany.
Bros M; Department of Dermatology, University Medical Center, Langenbeckstr. 1, 55131 Mainz, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Mar 30; Vol. 25 (7). Date of Electronic Publication: 2024 Mar 30.
Typ publikacji:
Journal Article
MeSH Terms:
Carrier Proteins*
Interleukin-6*/genetics
Animals ; Mice ; Lipopolysaccharides ; Macrophages ; Cytokines ; 3' Untranslated Regions
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Activated fibroblasts modify keratinocyte stem niche through TET1 and IL-6 to promote their rapid transformation in a mouse model of prenatal arsenic exposure.
Autorzy:
Chauhan A; Academy of Scientific and Innovative Research, Ghaziabad, 201002, India.; Systems Toxicology Group, FEST Division, CSIR-Indian Institute of Toxicology Research, Vishvigyan Bhawan, 31, Mahatma Gandhi Marg, Lucknow, 226001, Uttar Pradesh, India.
Gangopadhyay S; Academy of Scientific and Innovative Research, Ghaziabad, 201002, India.; Systems Toxicology Group, FEST Division, CSIR-Indian Institute of Toxicology Research, Vishvigyan Bhawan, 31, Mahatma Gandhi Marg, Lucknow, 226001, Uttar Pradesh, India.
Koshta K; Academy of Scientific and Innovative Research, Ghaziabad, 201002, India.; Systems Toxicology Group, FEST Division, CSIR-Indian Institute of Toxicology Research, Vishvigyan Bhawan, 31, Mahatma Gandhi Marg, Lucknow, 226001, Uttar Pradesh, India.
Singh S; Academy of Scientific and Innovative Research, Ghaziabad, 201002, India.; Systems Toxicology Group, FEST Division, CSIR-Indian Institute of Toxicology Research, Vishvigyan Bhawan, 31, Mahatma Gandhi Marg, Lucknow, 226001, Uttar Pradesh, India.
Singh D; Animal Facility, CSIR-Indian Institute of Toxicology Research (CSIR-IITR), Vishvigyan Bhawan, 31, Mahatma Gandhi Marg, Lucknow, 226001, Uttar Pradesh, India.
Srivastava V; Academy of Scientific and Innovative Research, Ghaziabad, 201002, India. .; Systems Toxicology Group, FEST Division, CSIR-Indian Institute of Toxicology Research, Vishvigyan Bhawan, 31, Mahatma Gandhi Marg, Lucknow, 226001, Uttar Pradesh, India. .
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Źródło:
Scientific reports [Sci Rep] 2024 Mar 22; Vol. 14 (1), pp. 6904. Date of Electronic Publication: 2024 Mar 22.
Typ publikacji:
Journal Article
MeSH Terms:
Interleukin-6*
Arsenic*
Mice ; Female ; Pregnancy ; Animals ; Keratinocytes/metabolism ; Signal Transduction/physiology ; Fibroblasts/metabolism ; DNA-Binding Proteins ; Proto-Oncogene Proteins/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Postoperative hyper-inflammation as a predictor of poor outcomes in patients with acute type A aortic dissection (ATAAD) undergoing surgical repair.
Autorzy:
Luo YX; Department of Cardio-Thoracic Surgery, Nanjing Drum Tower Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing, China.
Matniyaz Y; Department of Cardio-Thoracic Surgery, Nanjing Drum Tower Hospital, affiliated Hospital of Medical School, Nanjing University, Number 321 Zhongshan Road, Nanjing, 210008, Jiangsu, China.; Department of Cardio-Thoracic Surgery, Affiliated Drum Tower Hospital, Medical School of Nanjing University, Nanjing, 210008, China.
Tang YX; Department of Cardio-Thoracic Surgery, Nanjing Drum Tower Hospital Clinical College of Nanjing University of Chinese Medicine, Nanjing, China.
Xue YX; Department of Cardio-Thoracic Surgery, Nanjing Drum Tower Hospital, affiliated Hospital of Medical School, Nanjing University, Number 321 Zhongshan Road, Nanjing, 210008, Jiangsu, China.
Jiang Y; Department of Cardio-Thoracic Surgery, Nanjing Drum Tower Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing, China.
Pan K; Department of Cardio-Thoracic Surgery, Nanjing Drum Tower Hospital Clinical College of Xuzhou Medical University, Nanjing, China.
Lv ZK; Department of Cardio-Thoracic Surgery, Nanjing Drum Tower Hospital, affiliated Hospital of Medical School, Nanjing University, Number 321 Zhongshan Road, Nanjing, 210008, Jiangsu, China.
Fan ZW; Department of Cardio-Thoracic Surgery, Nanjing Drum Tower Hospital Clinical College of Nanjing University of Chinese Medicine, Nanjing, China.
Wang K; Department of Cardio-Thoracic Surgery, Nanjing Drum Tower Hospital Clinical College of Xuzhou Medical University, Nanjing, China.
Zhang HT; Department of Cardio-Thoracic Surgery, Nanjing Drum Tower Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing, China.
Zhang H; Department of Cardio-Thoracic Surgery, Nanjing Drum Tower Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing, China.
Wang WZ; Department of Cardio-Thoracic Surgery, Nanjing Drum Tower Hospital, affiliated Hospital of Medical School, Nanjing University, Number 321 Zhongshan Road, Nanjing, 210008, Jiangsu, China.
Pan T; Department of Cardio-Thoracic Surgery, Nanjing Drum Tower Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing, China. pan_.; Department of Cardio-Thoracic Surgery, Nanjing Drum Tower Hospital, affiliated Hospital of Medical School, Nanjing University, Number 321 Zhongshan Road, Nanjing, 210008, Jiangsu, China. pan_.
Wang DJ; Department of Cardio-Thoracic Surgery, Nanjing Drum Tower Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing, China. dongjin_.; Department of Cardio-Thoracic Surgery, Nanjing Drum Tower Hospital, affiliated Hospital of Medical School, Nanjing University, Number 321 Zhongshan Road, Nanjing, 210008, Jiangsu, China. dongjin_.; Department of Cardio-Thoracic Surgery, Nanjing Drum Tower Hospital Clinical College of Nanjing University of Chinese Medicine, Nanjing, China. dongjin_.; Department of Cardio-Thoracic Surgery, Nanjing Drum Tower Hospital Clinical College of Xuzhou Medical University, Nanjing, China. dongjin_.
Fan FD; Department of Cardio-Thoracic Surgery, Nanjing Drum Tower Hospital, affiliated Hospital of Medical School, Nanjing University, Number 321 Zhongshan Road, Nanjing, 210008, Jiangsu, China. .
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Źródło:
Journal of cardiothoracic surgery [J Cardiothorac Surg] 2024 Mar 19; Vol. 19 (1), pp. 138. Date of Electronic Publication: 2024 Mar 19.
Typ publikacji:
Journal Article
MeSH Terms:
Interleukin-6*
Aortic Dissection*/surgery
Humans ; Inflammation ; Biomarkers ; Risk Factors ; Procalcitonin ; C-Reactive Protein ; Retrospective Studies
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
ART1 knockdown decreases the IL-6-induced proliferation of colorectal cancer cells.
Autorzy:
Lin T; Department of Pathology, Molecular Medicine and Cancer Research Center, Basic Medicine College, Chongqing Medical University, Chongqing, 400016, P.R. China.
Zhang S; Department of Pathology, Molecular Medicine and Cancer Research Center, Basic Medicine College, Chongqing Medical University, Chongqing, 400016, P.R. China.; Molecular Medicine Diagnostic and Testing Center, Chongqing Medical University, Chongqing, 400016, P.R. China.
Tang Y; Department of Pathology, Molecular Medicine and Cancer Research Center, Basic Medicine College, Chongqing Medical University, Chongqing, 400016, P.R. China.; Department of Pathology, the First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, P.R. China.
Xiao M; Department of Pathology, Molecular Medicine and Cancer Research Center, Basic Medicine College, Chongqing Medical University, Chongqing, 400016, P.R. China.; Molecular Medicine Diagnostic and Testing Center, Chongqing Medical University, Chongqing, 400016, P.R. China.
Li M; Department of Pathology, Molecular Medicine and Cancer Research Center, Basic Medicine College, Chongqing Medical University, Chongqing, 400016, P.R. China.; Department of Pathology, the First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, P.R. China.
Gong H; Department of Pathology, Molecular Medicine and Cancer Research Center, Basic Medicine College, Chongqing Medical University, Chongqing, 400016, P.R. China.
Xie H; Department of Pathology, Molecular Medicine and Cancer Research Center, Basic Medicine College, Chongqing Medical University, Chongqing, 400016, P.R. China.
Wang Y; Department of Pathology, Molecular Medicine and Cancer Research Center, Basic Medicine College, Chongqing Medical University, Chongqing, 400016, P.R. China. .; Molecular Medicine Diagnostic and Testing Center, Chongqing Medical University, Chongqing, 400016, P.R. China. .; Department of Pathology, the First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, P.R. China. .
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Źródło:
BMC cancer [BMC Cancer] 2024 Mar 19; Vol. 24 (1), pp. 354. Date of Electronic Publication: 2024 Mar 19.
Typ publikacji:
Journal Article
MeSH Terms:
Interleukin-6*/genetics
Colorectal Neoplasms*/pathology
Humans ; Animals ; Mice ; ADP Ribose Transferases/genetics ; ADP Ribose Transferases/metabolism ; Cytokine Receptor gp130/genetics ; Cell Line, Tumor ; Poly(ADP-ribose) Polymerases/genetics ; Cell Proliferation ; GPI-Linked Proteins/metabolism
Czasopismo naukowe
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Tytuł:
Mechanical Stress Induces Sodium Entry and Osmoprotective Responses in Murine Synovial Fibroblasts.
Autorzy:
Proff A; Institute for Medical Microbiology, Immunology, and Hygiene, Center for Molecular Medicine Cologne (CMMC), University Hospital Cologne and Faculty of Medicine, University of Cologne, 50935 Cologne, Germany.
Nazet U; Department of Orthodontics, University Hospital Regensburg, 93053 Regensburg, Germany.
Schröder A; Department of Orthodontics, University Hospital Regensburg, 93053 Regensburg, Germany.; Institute for Medical Microbiology and Hygiene, University Hospital Regensburg, 93053 Regensburg, Germany.
Jantsch J; Institute for Medical Microbiology, Immunology, and Hygiene, Center for Molecular Medicine Cologne (CMMC), University Hospital Cologne and Faculty of Medicine, University of Cologne, 50935 Cologne, Germany.
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Źródło:
Cells [Cells] 2024 Mar 13; Vol. 13 (6). Date of Electronic Publication: 2024 Mar 13.
Typ publikacji:
Journal Article
MeSH Terms:
Interleukin-6*/metabolism
Osteoarthritis*/metabolism
Animals ; Mice ; Cyclooxygenase 2/metabolism ; Sodium/metabolism ; Stress, Mechanical ; Receptor Activator of Nuclear Factor-kappa B/metabolism ; Fibroblasts/metabolism
Czasopismo naukowe
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Tytuł:
Interleukin-6: An Under-Appreciated Inducer of Thermogenic Adipocyte Differentiation.
Autorzy:
Radványi Á; Department of Pediatrics, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary.
Röszer T; Department of Pediatrics, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 28; Vol. 25 (5). Date of Electronic Publication: 2024 Feb 28.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Interleukin-6*
Adipose Tissue*
Humans ; Adipocytes ; Cytokines ; Thermogenesis ; Inflammation ; Adipose Tissue, Brown
Czasopismo naukowe
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Tytuł:
The Prolonged Activation of the p65 Subunit of the NF-Kappa-B Nuclear Factor Sustains the Persistent Effect of Advanced Glycation End Products on Inflammatory Sensitization in Macrophages.
Autorzy:
Assis SIS; Laboratório de Lípides (LIM 10), Hospital das Clínicas (HCFMUSP) da Faculdade de Medicina da Universidade de São Paulo, São Paulo 01246-000, Brazil.
Amendola LS; Laboratório de Lípides (LIM 10), Hospital das Clínicas (HCFMUSP) da Faculdade de Medicina da Universidade de São Paulo, São Paulo 01246-000, Brazil.
Okamoto MM; Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of São Paulo, São Paulo 05508-000, Brazil.
Ferreira GDS; Laboratório de Lípides (LIM 10), Hospital das Clínicas (HCFMUSP) da Faculdade de Medicina da Universidade de São Paulo, São Paulo 01246-000, Brazil.
Iborra RT; Ciências Biológicas e da Saúde, Campos Mooca, Universidade São Judas Tadeu, São Paulo 03408-050, Brazil.
Santos DR; Laboratório de Lípides (LIM 10), Hospital das Clínicas (HCFMUSP) da Faculdade de Medicina da Universidade de São Paulo, São Paulo 01246-000, Brazil.
Santana MFM; Laboratório de Lípides (LIM 10), Hospital das Clínicas (HCFMUSP) da Faculdade de Medicina da Universidade de São Paulo, São Paulo 01246-000, Brazil.
Santana KG; Laboratório de Lípides (LIM 10), Hospital das Clínicas (HCFMUSP) da Faculdade de Medicina da Universidade de São Paulo, São Paulo 01246-000, Brazil.
Correa-Giannella ML; Laboratório de Carboidratos e Radioimunoensaio (LIM 18), Hospital das Clínicas (HCFMUSP) da Faculdade de Medicina da Universidade de São Paulo, São Paulo 01246-000, Brazil.
Barbeiro DF; Laboratório de Emergências Clínicas (LIM 51), Hospital das Clínicas (HCFMUSP) da Faculdade de Medicina da Universidade de São Paulo, São Paulo 01246-000, Brazil.
Soriano FG; Laboratório de Emergências Clínicas (LIM 51), Hospital das Clínicas (HCFMUSP) da Faculdade de Medicina da Universidade de São Paulo, São Paulo 01246-000, Brazil.
Machado UF; Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of São Paulo, São Paulo 05508-000, Brazil.
Passarelli M; Laboratório de Lípides (LIM 10), Hospital das Clínicas (HCFMUSP) da Faculdade de Medicina da Universidade de São Paulo, São Paulo 01246-000, Brazil.; Programa de Pós-Graduação em Medicina, Universidade Nove de Julho, São Paulo 01525-000, Brazil.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 27; Vol. 25 (5). Date of Electronic Publication: 2024 Feb 27.
Typ publikacji:
Journal Article
MeSH Terms:
NF-kappa B*/metabolism
Interleukin-6*/metabolism
Lipopolysaccharides/pharmacology ; Macrophages/metabolism ; Glycation End Products, Advanced/metabolism ; Albumins/metabolism
Czasopismo naukowe
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Tytuł:
Inhibitory Effects of Eicosapentaenoic Acid on Vascular Endothelial Growth Factor-Induced Monocyte Chemoattractant Protein-1, Interleukin-6, and Interleukin-8 in Human Vascular Endothelial Cells.
Autorzy:
Takenoshita Y; Institute for Clinical Research, NHO Kagoshima Medical Center, Kagoshima 892-0853, Japan.
Tokito A; Institute for Clinical Research, NHO Kagoshima Medical Center, Kagoshima 892-0853, Japan.
Jougasaki M; Institute for Clinical Research, NHO Kagoshima Medical Center, Kagoshima 892-0853, Japan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 27; Vol. 25 (5). Date of Electronic Publication: 2024 Feb 27.
Typ publikacji:
Journal Article
MeSH Terms:
Chemokine CCL2*/metabolism
Interleukin-6*/metabolism
Humans ; Interleukin-8/metabolism ; NF-kappa B/metabolism ; Vascular Endothelial Growth Factor A/metabolism ; Eicosapentaenoic Acid/pharmacology ; Human Umbilical Vein Endothelial Cells/metabolism ; p38 Mitogen-Activated Protein Kinases/metabolism
Czasopismo naukowe
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Tytuł:
Immunoassay System Based on the Technology of Time-Resolved Fluorescence Resonance Energy Transfer.
Autorzy:
Xu Z; Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, China.
Zhou H; Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, China.
Li L; Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, China.
Chen Z; Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, China.
Zhang X; Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, China.
Feng Y; Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, China.
Wang J; Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, China.
Li Y; Chongqing Guoke Medical Innovation Technology Development Co., Ltd., Chongqing 401122, China.
Wu Y; Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, China.
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Źródło:
Sensors (Basel, Switzerland) [Sensors (Basel)] 2024 Feb 22; Vol. 24 (5). Date of Electronic Publication: 2024 Feb 22.
Typ publikacji:
Journal Article
MeSH Terms:
Fluorescence Resonance Energy Transfer*/methods
Interleukin-6*
Immunoassay/methods ; Procalcitonin ; Luminescence ; C-Reactive Protein
Czasopismo naukowe
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Tytuł:
Semen Protein CRISP3 Promotes Reproductive Performance of Boars through Immunomodulation.
Autorzy:
Bu Y; State Key Laboratory of Swine and Poultry Breeding Industry, National Engineering Research Center for Breeding Swine Industry, Guangdong Provincial Key Laboratory of Agro-Animal Genomics and Molecular Breeding, College of Animal Science, South China Agricultural University, Guangdong 510642, China.
Wang P; State Key Laboratory of Swine and Poultry Breeding Industry, National Engineering Research Center for Breeding Swine Industry, Guangdong Provincial Key Laboratory of Agro-Animal Genomics and Molecular Breeding, College of Animal Science, South China Agricultural University, Guangdong 510642, China.
Li S; State Key Laboratory of Swine and Poultry Breeding Industry, National Engineering Research Center for Breeding Swine Industry, Guangdong Provincial Key Laboratory of Agro-Animal Genomics and Molecular Breeding, College of Animal Science, South China Agricultural University, Guangdong 510642, China.
Li L; State Key Laboratory of Swine and Poultry Breeding Industry, National Engineering Research Center for Breeding Swine Industry, Guangdong Provincial Key Laboratory of Agro-Animal Genomics and Molecular Breeding, College of Animal Science, South China Agricultural University, Guangdong 510642, China.
Zhang S; State Key Laboratory of Swine and Poultry Breeding Industry, National Engineering Research Center for Breeding Swine Industry, Guangdong Provincial Key Laboratory of Agro-Animal Genomics and Molecular Breeding, College of Animal Science, South China Agricultural University, Guangdong 510642, China.
Wei H; State Key Laboratory of Swine and Poultry Breeding Industry, National Engineering Research Center for Breeding Swine Industry, Guangdong Provincial Key Laboratory of Agro-Animal Genomics and Molecular Breeding, College of Animal Science, South China Agricultural University, Guangdong 510642, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 14; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 14.
Typ publikacji:
Journal Article
MeSH Terms:
Fertility*/genetics
Interleukin-6*/metabolism
Semen*/physiology
Seminal Proteins*/physiology
Swine*/growth & development
Swine*/immunology
Immunomodulation*
Animals ; Female ; Male ; Pregnancy ; Litter Size ; Semen Analysis ; Sperm Motility ; Spermatozoa/metabolism
Czasopismo naukowe
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