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Tytuł :
Upregulation of TNF-α and IL-6 induces preterm premature rupture of membranes by activation of ADAMTS-9 in embryonic membrane cells.
Autorzy :
Li W; Tianjin Key Laboratory of Human Development and Reproductive Regulation, China; Maternity Hospital of Nankai University, China.
Zhao X; Tianjin Central Hospital of Gynecology Obstetrics, China.
Li S; Tianjin Key Laboratory of Human Development and Reproductive Regulation, China; Tianjin Central Hospital of Gynecology Obstetrics, China.
Chen X; Tianjin Key Laboratory of Human Development and Reproductive Regulation, China; Tianjin Central Hospital of Gynecology Obstetrics, China.
Cui H; Tianjin Central Hospital of Gynecology Obstetrics, China.
Chang Y; Tianjin Key Laboratory of Human Development and Reproductive Regulation, China; Tianjin Central Hospital of Gynecology Obstetrics, China. Electronic address: .
Zhang R; Guangdong Province Key Laboratory for Biotechnology Drug Candidates, School of Life Sciences and Biopharmaceutics, China; Guangdong Pharmaceutical University, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 Nov 01; Vol. 260, pp. 118237. Date of Electronic Publication: 2020 Aug 08.
Typ publikacji :
Journal Article
MeSH Terms :
ADAMTS9 Protein/*physiology
Fetal Membranes, Premature Rupture/*physiopathology
Interleukin-6/*physiology
Tumor Necrosis Factor-alpha/*physiology
ADAMTS9 Protein/genetics ; Adult ; Animals ; Apoptosis ; Cell Line ; Female ; Gene Knockdown Techniques ; Gestational Age ; Humans ; Inflammation/physiopathology ; Interleukin-6/genetics ; Macrophages/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Placenta/chemistry ; Pregnancy ; Premature Birth/physiopathology ; RNA, Messenger/analysis ; THP-1 Cells ; Tumor Necrosis Factor-alpha/genetics ; Up-Regulation
SCR Disease Name :
Preterm Premature Rupture of the Membranes
Czasopismo naukowe
Tytuł :
Cytokine prediction of mortality in COVID19 patients.
Autorzy :
Mandel M; Blood Bank, Sheba Medical Center, Tel-Hashomer, Sackler School of Medicine, Tel-Aviv University, Israel. Electronic address: .
Harari G; Medistat, Tel-Aviv, Sackler School of Medicine, Tel-Aviv University, Israel.
Gurevich M; Neuroimmune Laboratory, Sheba Medical Center, Tel-Hashomer, and Sackler School of Medicine, Tel-Aviv University, Israel.
Achiron A; Neuroimmune Laboratory, Sheba Medical Center, Tel-Hashomer, and Sackler School of Medicine, Tel-Aviv University, Israel.
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Źródło :
Cytokine [Cytokine] 2020 Oct; Vol. 134, pp. 155190. Date of Electronic Publication: 2020 Jul 10.
Typ publikacji :
Journal Article
MeSH Terms :
Coronavirus Infections/*mortality
Interleukin-1beta/*blood
Interleukin-6/*blood
Interleukin-8/*blood
Pneumonia, Viral/*mortality
Tumor Necrosis Factor-alpha/*blood
Betacoronavirus/immunology ; Coronavirus Infections/blood ; Coronavirus Infections/immunology ; Cytokine Release Syndrome/blood ; Cytokine Release Syndrome/mortality ; Enzyme-Linked Immunosorbent Assay ; Female ; Humans ; Kaplan-Meier Estimate ; Male ; Middle Aged ; Pandemics ; Pneumonia, Viral/blood ; Pneumonia, Viral/immunology ; Prognosis ; Prospective Studies
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Immunomodulatory activity of a novel polysaccharide extracted from Huangshui on THP-1 cells through NO production and increased IL-6 and TNF-α expression.
Autorzy :
Huo J; School of Food Science and Engineering, South China University of Technology, Guangzhou 510640, China; Key Laboratory of Brewing Molecular Engineering of China Light Industry, Beijing Technology and Business University, Beijing 100048, China; Beijing Laboratory of Food Quality and Safety, Beijing Technology and Business University, Beijing 100048, China.
Wu J; Key Laboratory of Brewing Molecular Engineering of China Light Industry, Beijing Technology and Business University, Beijing 100048, China; Beijing Laboratory of Food Quality and Safety, Beijing Technology and Business University, Beijing 100048, China. Electronic address: .
Zhao M; School of Food Science and Engineering, South China University of Technology, Guangzhou 510640, China.
Sun W; School of Food Science and Engineering, South China University of Technology, Guangzhou 510640, China.
Sun J; Key Laboratory of Brewing Molecular Engineering of China Light Industry, Beijing Technology and Business University, Beijing 100048, China; Beijing Laboratory of Food Quality and Safety, Beijing Technology and Business University, Beijing 100048, China.
Li H; Key Laboratory of Brewing Molecular Engineering of China Light Industry, Beijing Technology and Business University, Beijing 100048, China; Beijing Laboratory of Food Quality and Safety, Beijing Technology and Business University, Beijing 100048, China.
Huang M; Key Laboratory of Brewing Molecular Engineering of China Light Industry, Beijing Technology and Business University, Beijing 100048, China; Beijing Laboratory of Food Quality and Safety, Beijing Technology and Business University, Beijing 100048, China. Electronic address: .
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Źródło :
Food chemistry [Food Chem] 2020 Nov 15; Vol. 330, pp. 127257. Date of Electronic Publication: 2020 Jun 05.
Typ publikacji :
Journal Article
MeSH Terms :
Immunosuppressive Agents/*pharmacology
Interleukin-6/*metabolism
Nitric Oxide/*biosynthesis
Polysaccharides/*pharmacology
Rivers/*chemistry
Tumor Necrosis Factor-alpha/*metabolism
Humans ; Immunosuppressive Agents/chemistry ; Molecular Weight ; Polysaccharides/chemistry ; THP-1 Cells
Czasopismo naukowe
Tytuł :
An inflammatory cytokine signature predicts COVID-19 severity and survival.
Autorzy :
Del Valle DM; Human Immune Monitoring Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Kim-Schulze S; Human Immune Monitoring Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Huang HH; Institute for Health Care Delivery Science, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; TCI Biostatistics Shared Resource Facility, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Beckmann ND; Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Nirenberg S; Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Scientific Computing, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Wang B; Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Lavin Y; Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Swartz TH; Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Madduri D; Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Stock A; Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Marron TU; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Xie H; Human Immune Monitoring Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Patel M; Human Immune Monitoring Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Tuballes K; Human Immune Monitoring Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Van Oekelen O; Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Rahman A; Human Immune Monitoring Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Kovatch P; Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Scientific Computing, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Aberg JA; Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Schadt E; Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Jagannath S; Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Mazumdar M; Institute for Health Care Delivery Science, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; TCI Biostatistics Shared Resource Facility, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Charney AW; Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Firpo-Betancourt A; Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Mendu DR; Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Jhang J; Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Reich D; Anesthesiology, Perioperative and Pain Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Sigel K; Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Cordon-Cardo C; Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Feldmann M; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK.
Parekh S; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Merad M; Human Immune Monitoring Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Gnjatic S; Human Immune Monitoring Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA. .; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. .; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. .; Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA. .; Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA. .; Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA. .
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Źródło :
Nature medicine [Nat Med] 2020 Oct; Vol. 26 (10), pp. 1636-1643. Date of Electronic Publication: 2020 Aug 24.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Coronavirus Infections/*immunology
Interleukin-1beta/*immunology
Interleukin-6/*immunology
Interleukin-8/*immunology
Pneumonia, Viral/*immunology
Tumor Necrosis Factor-alpha/*immunology
Aged ; Betacoronavirus ; Coronavirus Infections/mortality ; Coronavirus Infections/physiopathology ; Coronavirus Infections/therapy ; Cytokines/immunology ; Female ; Hospitalization ; Humans ; Male ; Middle Aged ; Pandemics ; Pneumonia, Viral/mortality ; Pneumonia, Viral/physiopathology ; Pneumonia, Viral/therapy ; Severity of Illness Index ; Survival Rate
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
First trimester inflammatory mediators in women with chronic hypertension.
Autorzy :
Nzelu D; Fetal Medicine Research Institute, King's College Hospital, London, UK.
Dumitrascu-Biris D; Fetal Medicine Research Institute, King's College Hospital, London, UK.
Karampitsakos T; Fetal Medicine Research Institute, King's College Hospital, London, UK.
Nicolaides KK; Fetal Medicine Research Institute, King's College Hospital, London, UK.; King's College London, London, UK.
Kametas NA; Fetal Medicine Research Institute, King's College Hospital, London, UK.; King's College London, London, UK.
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Źródło :
Acta obstetricia et gynecologica Scandinavica [Acta Obstet Gynecol Scand] 2020 Sep; Vol. 99 (9), pp. 1198-1205. Date of Electronic Publication: 2020 Jun 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Endothelins/*blood
Hypertension/*blood
Inflammation Mediators/*blood
Interleukin-6/*blood
Pregnancy Trimester, First/*blood
Tumor Necrosis Factor-alpha/*blood
Vascular Cell Adhesion Molecule-1/*blood
Adult ; Biomarkers/blood ; Case-Control Studies ; Female ; Gestational Age ; Humans ; Pre-Eclampsia/blood ; Pregnancy
Czasopismo naukowe
Tytuł :
Inhibition of Pro-Inflammatory Cytokine Secretion by Select Antioxidants in Human Coronary Artery Endothelial Cells.
Autorzy :
Haas MJ; Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Florida Jacksonville College of Medicine, Jacksonville, FL 32209.
Jurado-Flores M; Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Florida Jacksonville College of Medicine, Jacksonville, FL 32209.
Hammoud R; Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Florida Jacksonville College of Medicine, Jacksonville, FL 32209.
Feng V; Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Florida Jacksonville College of Medicine, Jacksonville, FL 32209.
Gonzales K; Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Florida Jacksonville College of Medicine, Jacksonville, FL 32209.
Onstead-Haas L; Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Florida Jacksonville College of Medicine, Jacksonville, FL 32209.
D Mooradian A; Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Florida Jacksonville College of Medicine, Jacksonville, FL 32209.
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Źródło :
International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition [Int J Vitam Nutr Res] 2020 Jan; Vol. 90 (1-2), pp. 103-112. Date of Electronic Publication: 2019 Mar 07.
Typ publikacji :
Journal Article
MeSH Terms :
Antioxidants*
Endothelial Cells*/drug effects
Endothelial Cells*/metabolism
Anti-Inflammatory Agents/*pharmacology
Coronary Vessels/*drug effects
Cytokines/*antagonists & inhibitors
Interleukin-6/*pharmacology
Tumor Necrosis Factor-alpha/*pharmacology
Cells, Cultured ; Coronary Vessels/cytology ; Cytokines/metabolism ; Humans ; Interleukin-6/metabolism
Czasopismo naukowe
Tytuł :
Blood biomarkers of traumatic brain injury and cognitive impairment in older veterans.
Autorzy :
Peltz CB; From San Francisco Veterans Affairs Health Care System (C.B.P., R.C.G., K.Y.), CA; Northern California Institute for Research and Education (C.B.P.), San Francisco; Uniformed Services University of the Health Sciences (K.K.), Rockville; NIH (J.G.), Bethesda, MD; Department of Neurology (R.D.-A.), University of Pennsylvania, Philadelphia; and Departments of Neurology (R.C.G., K.Y.), Psychiatry (K.Y.), and Epidemiology and Biostatistics (K.Y.), University of California, San Francisco. .
Kenney K; From San Francisco Veterans Affairs Health Care System (C.B.P., R.C.G., K.Y.), CA; Northern California Institute for Research and Education (C.B.P.), San Francisco; Uniformed Services University of the Health Sciences (K.K.), Rockville; NIH (J.G.), Bethesda, MD; Department of Neurology (R.D.-A.), University of Pennsylvania, Philadelphia; and Departments of Neurology (R.C.G., K.Y.), Psychiatry (K.Y.), and Epidemiology and Biostatistics (K.Y.), University of California, San Francisco.
Gill J; From San Francisco Veterans Affairs Health Care System (C.B.P., R.C.G., K.Y.), CA; Northern California Institute for Research and Education (C.B.P.), San Francisco; Uniformed Services University of the Health Sciences (K.K.), Rockville; NIH (J.G.), Bethesda, MD; Department of Neurology (R.D.-A.), University of Pennsylvania, Philadelphia; and Departments of Neurology (R.C.G., K.Y.), Psychiatry (K.Y.), and Epidemiology and Biostatistics (K.Y.), University of California, San Francisco.
Diaz-Arrastia R; From San Francisco Veterans Affairs Health Care System (C.B.P., R.C.G., K.Y.), CA; Northern California Institute for Research and Education (C.B.P.), San Francisco; Uniformed Services University of the Health Sciences (K.K.), Rockville; NIH (J.G.), Bethesda, MD; Department of Neurology (R.D.-A.), University of Pennsylvania, Philadelphia; and Departments of Neurology (R.C.G., K.Y.), Psychiatry (K.Y.), and Epidemiology and Biostatistics (K.Y.), University of California, San Francisco.
Gardner RC; From San Francisco Veterans Affairs Health Care System (C.B.P., R.C.G., K.Y.), CA; Northern California Institute for Research and Education (C.B.P.), San Francisco; Uniformed Services University of the Health Sciences (K.K.), Rockville; NIH (J.G.), Bethesda, MD; Department of Neurology (R.D.-A.), University of Pennsylvania, Philadelphia; and Departments of Neurology (R.C.G., K.Y.), Psychiatry (K.Y.), and Epidemiology and Biostatistics (K.Y.), University of California, San Francisco.
Yaffe K; From San Francisco Veterans Affairs Health Care System (C.B.P., R.C.G., K.Y.), CA; Northern California Institute for Research and Education (C.B.P.), San Francisco; Uniformed Services University of the Health Sciences (K.K.), Rockville; NIH (J.G.), Bethesda, MD; Department of Neurology (R.D.-A.), University of Pennsylvania, Philadelphia; and Departments of Neurology (R.C.G., K.Y.), Psychiatry (K.Y.), and Epidemiology and Biostatistics (K.Y.), University of California, San Francisco.
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Źródło :
Neurology [Neurology] 2020 Sep 01; Vol. 95 (9), pp. e1126-e1133. Date of Electronic Publication: 2020 Jun 22.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Veterans*
Brain Injuries, Traumatic/*blood
Cognitive Dysfunction/*blood
Interleukin-6/*blood
Neurofilament Proteins/*blood
Tumor Necrosis Factor-alpha/*blood
tau Proteins/*blood
Aged ; Aged, 80 and over ; Amyloid beta-Peptides/blood ; Biomarkers/blood ; Case-Control Studies ; Exosomes/metabolism ; Female ; Glial Fibrillary Acidic Protein/blood ; Humans ; Interleukin-10/blood ; Male ; Mental Status and Dementia Tests ; Neural Cell Adhesion Molecule L1/metabolism ; Neuropsychological Tests ; Peptide Fragments/blood ; Phosphorylation ; alpha-Synuclein/blood
Czasopismo naukowe
Tytuł :
Melatonin regulates the expression of inflammatory cytokines, VEGF and apoptosis in diabetic retinopathy in rats.
Autorzy :
Ferreira de Melo IM; Department of Morphology and Animal Physiology, Federal Rural University of Pernambuco, Recife, Brazil. Electronic address: .
Martins Ferreira CG; Department of Morphology and Animal Physiology, Federal Rural University of Pernambuco, Recife, Brazil. Electronic address: .
Lima da Silva Souza EH; Department of Veterinary Medicine, Federal Rural University of Pernambuco, Recife, Brazil. Electronic address: .
Almeida LL; Department of Biological Sciences, Cariri Regional University, Crato, Brazil. Electronic address: .
Bezerra de Sá F; Department of Morphology and Animal Physiology, Federal Rural University of Pernambuco, Recife, Brazil. Electronic address: .
Cavalcanti Lapa Neto CJ; Department of Morphology and Animal Physiology, Federal Rural University of Pernambuco, Recife, Brazil. Electronic address: .
Paz de Castro MV; Department of Morphology and Animal Physiology, Federal Rural University of Pernambuco, Recife, Brazil. Electronic address: .
Teixeira VW; Department of Morphology and Animal Physiology, Federal Rural University of Pernambuco, Recife, Brazil. Electronic address: .
Coelho Teixeira ÁA; Department of Morphology and Animal Physiology, Federal Rural University of Pernambuco, Recife, Brazil. Electronic address: .
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Źródło :
Chemico-biological interactions [Chem Biol Interact] 2020 Aug 25; Vol. 327, pp. 109183. Date of Electronic Publication: 2020 Jun 15.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis/*drug effects
Diabetic Retinopathy/*drug therapy
Interleukin-6/*metabolism
Melatonin/*therapeutic use
Tumor Necrosis Factor-alpha/*metabolism
Vascular Endothelial Growth Factor A/*metabolism
Animals ; Diabetes Mellitus, Experimental/complications ; Diabetic Retinopathy/etiology ; Diabetic Retinopathy/pathology ; Rats, Wistar ; Retina/pathology
Czasopismo naukowe
Tytuł :
Pediatric Crohn Disease and Multisystem Inflammatory Syndrome in Children (MIS-C) and COVID-19 Treated With Infliximab.
Autorzy :
Dolinger MT; Department of Pediatric Gastroenterology, Susan and Leonard Feinstein IBD Clinical Center, Icahn School of Medicine at Mount Sinai, New York, NY.
Person H
Smith R
Jarchin L
Pittman N
Dubinsky MC
Lai J
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Źródło :
Journal of pediatric gastroenterology and nutrition [J Pediatr Gastroenterol Nutr] 2020 Aug; Vol. 71 (2), pp. 153-155.
Typ publikacji :
Case Reports; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Coronavirus Infections/*drug therapy
Crohn Disease/*complications
Genetic Diseases, X-Linked/*complications
Ichthyosiform Erythroderma, Congenital/*complications
Infliximab/*therapeutic use
Interleukin-6/*blood
Interleukin-8/*blood
Limb Deformities, Congenital/*complications
Pneumonia, Viral/*drug therapy
Tumor Necrosis Factor-alpha/*antagonists & inhibitors
Abnormalities, Multiple ; Adolescent ; Antirheumatic Agents/therapeutic use ; Betacoronavirus ; Coronavirus Infections/complications ; Coronavirus Infections/virology ; Humans ; Male ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/virology ; Tumor Necrosis Factor-alpha/blood
SCR Disease Name :
COVID-19; Congenital Hemidysplasia with Ichthyosiform Erythroderma and Limb Defects; Pediatric Crohn's disease
Czasopismo naukowe
Tytuł :
TNF deficiency dysregulates inflammatory cytokine production, leading to lung pathology and death during respiratory poxvirus infection.
Autorzy :
Tuazon Kels MJ; Infection and Immunity Group, Department of Immunology, The John Curtin School of Medical Research, Australian National University, Canberra, ACT 2601, Australia.
Ng E; Infection and Immunity Group, Department of Immunology, The John Curtin School of Medical Research, Australian National University, Canberra, ACT 2601, Australia.
Al Rumaih Z; Infection and Immunity Group, Department of Immunology, The John Curtin School of Medical Research, Australian National University, Canberra, ACT 2601, Australia.
Pandey P; Viral Immunology and Immunopathology Group, Tasmanian School of Medicine, University of Tasmania, Hobart, TAS 7000, Australia.
Ruuls SR; Genmab, 3584 CT Utrecht, The Netherlands.
Korner H; Menzies Institute for Medical Research, University of Tasmania, Hobart, TAS 7000, Australia.
Newsome TP; School of Life and Environmental Sciences, University of Sydney, Sydney, NSW 2006, Australia.
Chaudhri G; Infection and Immunity Group, Department of Immunology, The John Curtin School of Medical Research, Australian National University, Canberra, ACT 2601, Australia.; Research School of Population Health, Australian National University, Canberra, ACT 2601, Australia.
Karupiah G; Infection and Immunity Group, Department of Immunology, The John Curtin School of Medical Research, Australian National University, Canberra, ACT 2601, Australia; .; Viral Immunology and Immunopathology Group, Tasmanian School of Medicine, University of Tasmania, Hobart, TAS 7000, Australia.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Jul 07; Vol. 117 (27), pp. 15935-15946. Date of Electronic Publication: 2020 Jun 22.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cytokines/*metabolism
Poxviridae/*metabolism
Poxviridae Infections/*virology
Tumor Necrosis Factor-alpha/*genetics
Tumor Necrosis Factor-alpha/*metabolism
Animals ; Cell Line, Tumor ; Female ; Interferon-gamma/metabolism ; Interleukin-10/metabolism ; Interleukin-6/metabolism ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Poxviridae/immunology ; Poxviridae Infections/immunology ; Poxviridae Infections/pathology ; Respiratory Tract Infections/immunology ; Respiratory Tract Infections/virology ; STAT3 Transcription Factor/genetics ; STAT3 Transcription Factor/metabolism ; Suppressor of Cytokine Signaling 3 Protein/metabolism ; Transforming Growth Factor beta/metabolism
Czasopismo naukowe
Tytuł :
High serum levels of IL-2R, IL-6, and TNF-α are associated with higher tumor burden and poorer outcome of follicular lymphoma patients in the rituximab era.
Autorzy :
Mozas P; Department of Hematology, Hospital Clínic de Barcelona, Barcelona, Spain. Electronic address: .
Rivas-Delgado A; Department of Hematology, Hospital Clínic de Barcelona, Barcelona, Spain. Electronic address: .
Rivero A; Department of Hematology, Hospital Clínic de Barcelona, Barcelona, Spain. Electronic address: .
Dlouhy I; Department of Hematology, Hospital Clínic de Barcelona, Barcelona, Spain. Electronic address: .
Nadeu F; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain. Electronic address: .
Balagué O; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain; Hematopathology Unit, Department of Pathology, Hospital Clínic de Barcelona, Barcelona, Spain; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain. Electronic address: .
González-Farré B; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain; Hematopathology Unit, Department of Pathology, Hospital Clínic de Barcelona, Barcelona, Spain; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain. Electronic address: .
Baumann T; Department of Hematology, Hospital Clínic de Barcelona, Barcelona, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain. Electronic address: .
Giné E; Department of Hematology, Hospital Clínic de Barcelona, Barcelona, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain. Electronic address: .
Delgado J; Department of Hematology, Hospital Clínic de Barcelona, Barcelona, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain. Electronic address: .
Villamor N; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain; Hematopathology Unit, Department of Pathology, Hospital Clínic de Barcelona, Barcelona, Spain. Electronic address: .
Campo E; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain; Hematopathology Unit, Department of Pathology, Hospital Clínic de Barcelona, Barcelona, Spain; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain; Universitat de Barcelona, Barcelona, Spain. Electronic address: .
Pérez-Galán P; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain. Electronic address: .
Filella X; Department of Biochemistry and Molecular Genetics, Hospital Clínic de Barcelona, Barcelona, Spain. Electronic address: .
Magnano L; Department of Hematology, Hospital Clínic de Barcelona, Barcelona, Spain; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain. Electronic address: .
López-Guillermo A; Department of Hematology, Hospital Clínic de Barcelona, Barcelona, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain; Universitat de Barcelona, Barcelona, Spain. Electronic address: .
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Źródło :
Leukemia research [Leuk Res] 2020 Jul; Vol. 94, pp. 106371. Date of Electronic Publication: 2020 May 19.
Typ publikacji :
Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Lymphoma, Follicular*/blood
Lymphoma, Follicular*/drug therapy
Lymphoma, Follicular*/mortality
Interleukin-6/*blood
Neoplasm Proteins/*blood
Receptors, Interleukin-2/*blood
Rituximab/*administration & dosage
Tumor Necrosis Factor-alpha/*blood
Adult ; Aged ; Aged, 80 and over ; Cost of Illness ; Disease-Free Survival ; Female ; Humans ; Male ; Middle Aged ; Survival Rate
Czasopismo naukowe
Tytuł :
Risk factors for insulin resistance in midlife Singaporean women.
Autorzy :
Sundström-Poromaa I; Department of Obstetrics and Gynecology, National University Hospital, National University of Singapore, Singapore 119228; Department of Women's and Children's Health, Uppsala University, 751 85 Uppsala, Sweden.
Thu WPP; Department of Obstetrics and Gynecology, National University Hospital, National University of Singapore, Singapore 119228.
Kramer MS; Department of Obstetrics and Gynecology, National University Hospital, National University of Singapore, Singapore 119228; Departments of Epidemiology, Biostatistics & Occupational Health and of Pediatrics, McGill University Faculty of Medicine, Montreal, QC H3G 1Y6, Canada.
Logan S; Department of Obstetrics and Gynecology, National University Hospital, National University of Singapore, Singapore 119228.
Cauley JA; Department of Epidemiology, University of Pittsburgh, Graduate School of Public Health, Pittsburgh, PA, United States.
Yong EL; Department of Obstetrics and Gynecology, National University Hospital, National University of Singapore, Singapore 119228. Electronic address: .
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Źródło :
Maturitas [Maturitas] 2020 Jul; Vol. 137, pp. 50-56. Date of Electronic Publication: 2020 Apr 27.
Typ publikacji :
Journal Article
MeSH Terms :
Intra-Abdominal Fat*
Insulin Resistance/*ethnology
Interleukin-6/*blood
Obesity/*physiopathology
Tumor Necrosis Factor-alpha/*blood
Aged ; Biomarkers/blood ; Blood Glucose/metabolism ; Body Mass Index ; C-Reactive Protein/metabolism ; China/ethnology ; Exercise ; Female ; Hand Strength ; Humans ; India/ethnology ; Insulin ; Malaysia/ethnology ; Middle Aged ; Obesity/blood ; Physical Functional Performance ; Risk Factors ; Singapore
Czasopismo naukowe
Tytuł :
Successful treatment of tumor necrosis factor inhibitor-resistant cutaneous polyarteritis nodosa with tocilizumab.
Autorzy :
Inoue N; Department of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan.
Shimizu M; Department of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan.
Mizuta M; Department of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan.
Yachie A; Department of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan.
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Źródło :
Pediatrics international : official journal of the Japan Pediatric Society [Pediatr Int] 2020 Jun; Vol. 62 (6), pp. 753-755. Date of Electronic Publication: 2020 Jun 08.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Antibodies, Monoclonal, Humanized/*administration & dosage
Polyarteritis Nodosa/*drug therapy
Tumor Necrosis Factor-alpha/*metabolism
Child ; Drug Resistance ; Female ; Humans ; Interleukin-6/blood ; Polyarteritis Nodosa/diagnosis ; Positron-Emission Tomography ; Skin/pathology ; Treatment Outcome ; Tumor Necrosis Factor Inhibitors/adverse effects ; Tumor Necrosis Factor Inhibitors/therapeutic use
Czasopismo naukowe
Tytuł :
Rapid alterations in neuroimmune gene expression after acute ethanol: Timecourse, sex differences and sensitivity to cranial surgery.
Autorzy :
Gano A; Developmental Exposure Alcohol Research Center (DEARC), Behavioral Neuroscience Program, Department of Psychology, Binghamton University, Binghamton, NY 13902-6000, United States of America.
Mondello JE; Developmental Exposure Alcohol Research Center (DEARC), Behavioral Neuroscience Program, Department of Psychology, Binghamton University, Binghamton, NY 13902-6000, United States of America.
Doremus-Fitzwater TL; Department of Psychology, Williams Hall, Ithaca College, 953 Danby Road, Ithaca, NY 14850, United States of America.
Deak T; Developmental Exposure Alcohol Research Center (DEARC), Behavioral Neuroscience Program, Department of Psychology, Binghamton University, Binghamton, NY 13902-6000, United States of America. Electronic address: .
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Źródło :
Journal of neuroimmunology [J Neuroimmunol] 2019 Dec 15; Vol. 337, pp. 577083. Date of Electronic Publication: 2019 Oct 15.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Catheterization*/methods
Sex Characteristics*
Ethanol/*administration & dosage
Interleukin-1beta/*biosynthesis
Interleukin-6/*biosynthesis
Tumor Necrosis Factor-alpha/*biosynthesis
Animals ; Ethanol/toxicity ; Female ; Gene Expression ; Interleukin-1beta/immunology ; Interleukin-6/immunology ; Male ; Rats ; Rats, Sprague-Dawley ; Skull/surgery ; Time Factors ; Tumor Necrosis Factor-alpha/immunology
Czasopismo naukowe
Tytuł :
Synthesis and in vitro and in vivo anti-inflammatory activity of novel 4-ferrocenylchroman-2-one derivatives.
Autorzy :
Guo WY; School of Food and Biological Engineering, Hefei University of Technology , Hefei , PR China.
Chen LZ; School of Pharmacy, Anhui Province Key Laboratory of Major Autoimmune Diseases, Anhui Medical University , Hefei , PR China.
Shen BN; School of Food and Biological Engineering, Hefei University of Technology , Hefei , PR China.
Liu XH; School of Pharmacy, Anhui Province Key Laboratory of Major Autoimmune Diseases, Anhui Medical University , Hefei , PR China.
Tai GP; Key Lab of Biofabrication of Anhui Higher Education Institution Centre for Advanced Biofabrication, Hefei University , Hefei , PR China.
Li QS; School of Food and Biological Engineering, Hefei University of Technology , Hefei , PR China.
Gao L; School of Food and Biological Engineering, Hefei University of Technology , Hefei , PR China.
Ruan BF; School of Food and Biological Engineering, Hefei University of Technology , Hefei , PR China.
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Źródło :
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2019 Dec; Vol. 34 (1), pp. 1678-1689.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Inflammatory Agents, Non-Steroidal/*pharmacology
Arthritis/*drug therapy
Chromones/*pharmacology
Interleukin-6/*antagonists & inhibitors
Mitogen-Activated Protein Kinases/*antagonists & inhibitors
NF-kappa B/*antagonists & inhibitors
Tumor Necrosis Factor-alpha/*antagonists & inhibitors
Animals ; Anti-Inflammatory Agents, Non-Steroidal/chemical synthesis ; Anti-Inflammatory Agents, Non-Steroidal/chemistry ; Arthritis/metabolism ; Cell Survival/drug effects ; Chromones/chemical synthesis ; Chromones/chemistry ; Dose-Response Relationship, Drug ; Freund's Adjuvant ; Interleukin-6/biosynthesis ; Lipopolysaccharides/antagonists & inhibitors ; Lipopolysaccharides/pharmacology ; Male ; Mice ; Mitogen-Activated Protein Kinases/metabolism ; Molecular Structure ; NF-kappa B/metabolism ; RAW 264.7 Cells ; Rats ; Rats, Sprague-Dawley ; Signal Transduction/drug effects ; Structure-Activity Relationship ; Tumor Necrosis Factor-alpha/biosynthesis
Czasopismo naukowe
Tytuł :
[The effect and mechanism of transient receptor potential M(2) in antigen-induced arthritis mice].
Autorzy :
Li MY; Department of Rheumatology and Immunology, Subsidiary Hospital, Southwestern Medical University, Luzhou, Sichuan Province 646000, China.
Zhao Y; Department of Rheumatology and Immunology, West China Hospital, Sichuan University, Chengdu 610041, China.
Luo YB; Department of Rheumatology and Immunology, West China Hospital, Sichuan University, Chengdu 610041, China.
Li YH; Department of Rheumatology and Immunology, West China Hospital, Sichuan University, Chengdu 610041, China.
Liu Y; Department of Rheumatology and Immunology, Subsidiary Hospital, Southwestern Medical University, Luzhou, Sichuan Province 646000, China; Department of Rheumatology and Immunology, West China Hospital, Sichuan University, Chengdu 610041, China.
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Źródło :
Zhonghua nei ke za zhi [Zhonghua Nei Ke Za Zhi] 2019 Dec 01; Vol. 58 (12), pp. 911-914.
Typ publikacji :
Journal Article
MeSH Terms :
Arthritis, Experimental/*immunology
Arthritis, Rheumatoid/*immunology
Chemokine CXCL6/*immunology
Interleukin-6/*immunology
Interleukin-8/*immunology
Serum Albumin, Bovine/*immunology
Tumor Necrosis Factor-alpha/*immunology
Animals ; Antigens/immunology ; Arthritis, Rheumatoid/genetics ; Chemokine CXCL6/genetics ; Interleukin-6/genetics ; Interleukin-8/genetics ; Knee Joint/immunology ; Knee Joint/pathology ; Mice ; Mice, Inbred C57BL ; Real-Time Polymerase Chain Reaction ; Synovial Membrane ; Tumor Necrosis Factor-alpha/genetics
Czasopismo naukowe
Tytuł :
MicroRNA-181b-5p modulates tumor necrosis factor-α-induced inflammatory responses by targeting interleukin-6 in cementoblasts.
Autorzy :
Wang X; The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) & Key Laboratory of Oral Biomedicine Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, China.
Sun H; The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) & Key Laboratory of Oral Biomedicine Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, China.; Department of Periodontology, School and Hospital of Stomatology, Wuhan University, Wuhan, China.
Liu H; The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) & Key Laboratory of Oral Biomedicine Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, China.; Department of Periodontology, School and Hospital of Stomatology, Wuhan University, Wuhan, China.
Ma L; The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) & Key Laboratory of Oral Biomedicine Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, China.
Jiang C; The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) & Key Laboratory of Oral Biomedicine Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, China.
Liao H; The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) & Key Laboratory of Oral Biomedicine Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, China.
Xu S; The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) & Key Laboratory of Oral Biomedicine Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, China.
Xiang J; The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) & Key Laboratory of Oral Biomedicine Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, China.; Department of Periodontology, School and Hospital of Stomatology, Wuhan University, Wuhan, China.
Cao Z; The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) & Key Laboratory of Oral Biomedicine Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, China.; Department of Periodontology, School and Hospital of Stomatology, Wuhan University, Wuhan, China.
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Źródło :
Journal of cellular physiology [J Cell Physiol] 2019 Dec; Vol. 234 (12), pp. 22719-22730. Date of Electronic Publication: 2019 May 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Dental Cementum/*drug effects
Interleukin-6/*metabolism
MicroRNAs/*metabolism
Periodontitis/*metabolism
Tumor Necrosis Factor-alpha/*pharmacology
Animals ; Apoptosis/drug effects ; Cell Line ; Dental Cementum/immunology ; Dental Cementum/metabolism ; Dental Cementum/pathology ; Disease Models, Animal ; Gene Expression Regulation ; Interleukin-6/genetics ; Mice ; MicroRNAs/genetics ; NF-kappa B/metabolism ; Periodontitis/genetics ; Periodontitis/immunology ; Periodontitis/pathology ; Signal Transduction
Czasopismo naukowe
Tytuł :
Trimethoxystilbene Reduces Nuclear Factor Kappa B, Interleukin-6, and Tumor Necrosis Factor- α Levels in Rats with Pulmonary Artery Hypertension.
Autorzy :
Shu J; The Department of Cardiothoracic Surgery, Xiangya Hospital, Central South University, Changsha, Hunan Province, China.
Liu W; The Department of Cardiothoracic Surgery, Xiangya Hospital, Central South University, Changsha, Hunan Province, China.
Han F; The Department of Cardiothoracic Surgery, Xiangya Hospital, Central South University, Changsha, Hunan Province, China.
Luo F; The Department of Cardiothoracic Surgery, Xiangya Hospital, Central South University, Changsha, Hunan Province, China.
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Źródło :
BioMed research international [Biomed Res Int] 2019 Nov 26; Vol. 2019, pp. 1219848. Date of Electronic Publication: 2019 Nov 26 (Print Publication: 2019).
Typ publikacji :
Journal Article
MeSH Terms :
Interleukin-6/*metabolism
NF-kappa B/*metabolism
Pulmonary Arterial Hypertension/*drug therapy
Pulmonary Artery/*drug effects
Tumor Necrosis Factor-alpha/*metabolism
Animals ; Cytokines/metabolism ; Disease Models, Animal ; Female ; Immunohistochemistry ; Interleukin-6/blood ; Lung/pathology ; Male ; Monocrotaline/therapeutic use ; NF-kappa B/blood ; Pregnancy ; Pulmonary Arterial Hypertension/pathology ; Pulmonary Artery/pathology ; Rats ; Rats, Sprague-Dawley ; Tumor Necrosis Factor-alpha/blood
Czasopismo naukowe
Tytuł :
Diastereoselective Synthesis of 3,4-Dihydropyran-3-carboxamides with in Vitro Anti-inflammatory Activity.
Autorzy :
Zeng LY; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences , Southern Medical University , Guangzhou 510515 , China.
Xi B; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences , Southern Medical University , Guangzhou 510515 , China.
Huang K; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences , Southern Medical University , Guangzhou 510515 , China.
Bi J; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences , Southern Medical University , Guangzhou 510515 , China.
Wei L; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences , Southern Medical University , Guangzhou 510515 , China.
Cai C; Chemical Engineering College , Nanjing University of Science and Technology , Nanjing 210094 , China.
Liu S; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences , Southern Medical University , Guangzhou 510515 , China.; State Key Laboratory of Organ Failure Research, Guangdong Provincial Institute of Nephrology , Southern Medical University , Guangzhou 510515 , China.
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Źródło :
ACS combinatorial science [ACS Comb Sci] 2019 Oct 14; Vol. 21 (10), pp. 656-665. Date of Electronic Publication: 2019 Sep 11.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Inflammatory Agents, Non-Steroidal/*pharmacology
Interleukin-6/*antagonists & inhibitors
Pyrans/*pharmacology
Tumor Necrosis Factor-alpha/*antagonists & inhibitors
Animals ; Anti-Inflammatory Agents, Non-Steroidal/chemical synthesis ; Anti-Inflammatory Agents, Non-Steroidal/chemistry ; Cell Survival/drug effects ; Cells, Cultured ; Combinatorial Chemistry Techniques ; Drug Design ; Humans ; Interleukin-6/biosynthesis ; Lipopolysaccharides/antagonists & inhibitors ; Lipopolysaccharides/pharmacology ; Mice ; Molecular Conformation ; Pyrans/chemical synthesis ; Pyrans/chemistry ; RAW 264.7 Cells ; Stereoisomerism ; Tumor Necrosis Factor-alpha/biosynthesis
Czasopismo naukowe
Tytuł :
Gut metabolites and inflammation factors in non-alcoholic fatty liver disease: A systematic review and meta-analysis.
Autorzy :
Pan X; Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha, China.
Wen SW; OMNI Research Group, Ottawa Hospital Research Institute, Ottawa, Canada.; Department of Obstetrics and Gynaecology and School of Epidemiology and Public Health, University of Ottawa Faculty of Medicine, Ottawa, Ontario, Canada.
Kaminga AC; Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha, China.; Department of Mathematics and Statistics, Mzuzu University, Mzuzu, Malawi.
Liu A; Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha, China. .
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Źródło :
Scientific reports [Sci Rep] 2020 Jun 01; Vol. 10 (1), pp. 8848. Date of Electronic Publication: 2020 Jun 01.
Typ publikacji :
Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't; Systematic Review
MeSH Terms :
Gastrointestinal Tract/*metabolism
Non-alcoholic Fatty Liver Disease/*pathology
Tumor Necrosis Factor-alpha/*metabolism
C-Reactive Protein/analysis ; Gastrointestinal Microbiome ; Humans ; Interleukin-6/metabolism ; Non-alcoholic Fatty Liver Disease/metabolism
Czasopismo naukowe

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