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Wyszukujesz frazę ""Interleukin-6"" wg kryterium: Temat


Tytuł:
Tumour-associated CD204 microglia/macrophages accumulate in perivascular and perinecrotic niches and correlate with an interleukin-6-enriched inflammatory profile in glioblastoma.
Autorzy:
Sørensen MD; Department of Pathology, Odense University Hospital, Odense, Denmark.; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
Kristensen BW; Department of Pathology, Odense University Hospital, Odense, Denmark.; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; Department of Pathology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.; Department of Clinical Medicine and Biotech Research and Innovation Center (BRIC), University of Copenhagen, Copenhagen, Denmark.
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Źródło:
Neuropathology and applied neurobiology [Neuropathol Appl Neurobiol] 2022 Feb; Vol. 48 (2), pp. e12772. Date of Electronic Publication: 2022 Jan 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Brain Neoplasms/*metabolism
Glioblastoma/*metabolism
Inflammation/*metabolism
Interleukin-6/*metabolism
Macrophages/*metabolism
Microglia/*metabolism
Aged ; Biomarkers, Tumor/metabolism ; Brain Neoplasms/pathology ; Female ; Glioblastoma/pathology ; Humans ; Immunohistochemistry ; Inflammation/pathology ; Macrophages/pathology ; Male ; Microglia/pathology ; Middle Aged ; Prognosis ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Mutant glucocorticoid receptor binding elements on the interleukin-6 promoter regulate dexamethasone effects.
Autorzy:
Chang WT; Department of Biological Science and Technology, Chung Hwa University of Medical Technology, Tainan, 701, Taiwan.
Hong MY; Department of Emergency Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Chen CL; Department of Physical Therapy, I-Shou University, Kaohsiung, Taiwan.
Hwang CY; Department of Emergency Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Tsai CC; Department of Nursing, Chung Hwa University of Medical Technology, Tainan, 701, Taiwan.
Chuang CC; Department of Emergency Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan. .
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Źródło:
BMC immunology [BMC Immunol] 2021 Mar 26; Vol. 22 (1), pp. 24. Date of Electronic Publication: 2021 Mar 26.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Anti-Inflammatory Agents/*pharmacology
Dexamethasone/*pharmacology
Inflammation/*immunology
Macrophages/*immunology
Receptors, Glucocorticoid/*metabolism
Animals ; Binding Sites/genetics ; Humans ; Inflammation/drug therapy ; Interleukin-6/metabolism ; Lipopolysaccharides/immunology ; Macrophages/drug effects ; Mice ; Mutation/genetics ; NF-kappa B/metabolism ; Promoter Regions, Genetic/genetics ; Protein Binding ; Protein Kinases/metabolism ; RAW 264.7 Cells ; Receptors, Glucocorticoid/genetics ; Transcription Factor AP-1/metabolism
Czasopismo naukowe
Tytuł:
Propolis attenuates lipopolysaccharide-induced inflammatory responses through intracellular ROS and NO levels along with downregulation of IL-1β and IL-6 expressions in murine RAW 264.7 macrophages.
Autorzy:
Asgharpour F; Student Research Committee, Babol University of Medical sciences, Babol, Iran.; Dental Materials Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.
Moghadamnia AA; Neuroscience Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.; Cellular and Molecular Biology Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.
Motallebnejad M; Oral Health Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.
Nouri HR; Cellular and Molecular Biology Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.
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Źródło:
Journal of food biochemistry [J Food Biochem] 2019 Aug; Vol. 43 (8), pp. e12926. Date of Electronic Publication: 2019 Jun 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Inflammation/*chemically induced
Interleukin-1beta/*metabolism
Interleukin-6/*metabolism
Lipopolysaccharides/*toxicity
Macrophages/*drug effects
Propolis/*pharmacology
Animals ; Cell Survival ; Gene Expression Regulation/drug effects ; Inflammation/drug therapy ; Interleukin-1beta/genetics ; Interleukin-6/genetics ; Macrophages/metabolism ; Mice ; Nitric Oxide/metabolism ; RAW 264.7 Cells ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł:
Isoorientin Inhibits Inflammation in Macrophages and Endotoxemia Mice by Regulating Glycogen Synthase Kinase 3 β .
Autorzy:
Li Y; Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, China.
Zhao Y; Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, China.
Tan X; Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, China.; Department of Molecular Biosciences and Bioengineering, University of Hawaii at Manoa, Honolulu, Hawaii 96822, USA.
Liu J; Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, China.
Zhi Y; Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, China.
Yi L; Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, China.
Bai S; Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, China.
Du Q; Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, China.
Li QX; Department of Molecular Biosciences and Bioengineering, University of Hawaii at Manoa, Honolulu, Hawaii 96822, USA.
Dong Y; Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, China.
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Źródło:
Mediators of inflammation [Mediators Inflamm] 2020 Oct 27; Vol. 2020, pp. 8704146. Date of Electronic Publication: 2020 Oct 27 (Print Publication: 2020).
Typ publikacji:
Journal Article
MeSH Terms:
Endotoxemia/*drug therapy
Glycogen Synthase Kinase 3 beta/*genetics
Inflammation/*drug therapy
Luteolin/*pharmacology
Macrophages/*drug effects
Animals ; Endotoxemia/metabolism ; Enzyme-Linked Immunosorbent Assay ; Extracellular Signal-Regulated MAP Kinases/metabolism ; Glycogen Synthase Kinase 3 beta/metabolism ; Heme Oxygenase-1/metabolism ; Heterocyclic Compounds, 3-Ring/pharmacology ; Interleukin-6/metabolism ; Lithium Chloride/pharmacology ; Macrophages/metabolism ; Male ; Membrane Proteins/metabolism ; Mice ; Mice, Inbred BALB C ; NF-E2-Related Factor 2/metabolism ; NF-kappa B p50 Subunit/metabolism ; Occludin/biosynthesis ; Phosphorylation ; RAW 264.7 Cells ; Real-Time Polymerase Chain Reaction ; Zonula Occludens-1 Protein/metabolism
Czasopismo naukowe
Tytuł:
Characterization of hepatic macrophages and evaluation of inflammatory response in heme oxygenase-1 deficient mice exposed to scAAV9 vectors.
Autorzy:
Tomczyk M; Department of Medical Biotechnology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Kraków, Poland.
Kraszewska I; Department of Medical Biotechnology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Kraków, Poland.
Mąka R; Department of Medical Biotechnology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Kraków, Poland.
Waligórska A; Department of Cell Biophysics, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Kraków, Poland.
Dulak J; Department of Medical Biotechnology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Kraków, Poland.
Jaźwa-Kusior A; Department of Medical Biotechnology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Kraków, Poland.
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Źródło:
PloS one [PLoS One] 2020 Oct 15; Vol. 15 (10), pp. e0240691. Date of Electronic Publication: 2020 Oct 15 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Genetic Vectors/*metabolism
Heme Oxygenase-1/*deficiency
Inflammation/*pathology
Liver/*pathology
Macrophages/*pathology
Animals ; Cells, Cultured ; Chemokine CCL2/metabolism ; Dependovirus/metabolism ; Gene Expression Regulation ; Green Fluorescent Proteins/metabolism ; HEK293 Cells ; Heme Oxygenase-1/metabolism ; Humans ; Inflammation/blood ; Inflammation/genetics ; Interleukin-6/blood ; Kupffer Cells/pathology ; Mice, Inbred C57BL ; Mice, Knockout ; Phenotype ; Signal Transduction/genetics ; Toll-Like Receptor 9/metabolism ; Transgenes
Czasopismo naukowe
Tytuł:
Acotiamide attenuates central urocortin 2-induced intestinal inflammatory responses, and urocortin 2 treatment reduces TNF-α productions in LPS-stimulated macrophage cell lines.
Autorzy:
Yamawaki H; Division of Gastroenterology, Nippon Medical School, Tokyo, Japan.
Futagami S; Division of Gastroenterology, Nippon Medical School, Tokyo, Japan.
Sakasegawa N; Division of Gastroenterology, Nippon Medical School, Tokyo, Japan.
Murakami M; Division of Gastroenterology, Nippon Medical School, Tokyo, Japan.
Agawa S; Division of Gastroenterology, Nippon Medical School, Tokyo, Japan.
Ikeda G; Division of Gastroenterology, Nippon Medical School, Tokyo, Japan.
Noda H; Division of Gastroenterology, Nippon Medical School, Tokyo, Japan.
Kirita K; Division of Gastroenterology, Nippon Medical School, Tokyo, Japan.
Gudis K; Division of Gastroenterology, Nippon Medical School, Tokyo, Japan.
Higuchi K; Division of Gastroenterology, Nippon Medical School, Tokyo, Japan.
Kodaka Y; Division of Gastroenterology, Nippon Medical School, Tokyo, Japan.
Ueki N; Division of Gastroenterology, Nippon Medical School, Tokyo, Japan.
Iwakiri K; Division of Gastroenterology, Nippon Medical School, Tokyo, Japan.
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Źródło:
Neurogastroenterology and motility [Neurogastroenterol Motil] 2020 Aug; Vol. 32 (8), pp. e13813. Date of Electronic Publication: 2020 Feb 07.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Urocortins*
Benzamides/*pharmacology
Gastrointestinal Agents/*pharmacology
Inflammation/*drug therapy
Intestines/*drug effects
Macrophages/*drug effects
Thiazoles/*pharmacology
Tumor Necrosis Factor-alpha/*metabolism
Animals ; Benzamides/therapeutic use ; Cell Line ; Gastrointestinal Agents/therapeutic use ; Inflammation/chemically induced ; Inflammation/metabolism ; Interleukin-6/metabolism ; Lipopolysaccharides ; Macrophages/metabolism ; Male ; Phosphorylation/drug effects ; Rats ; Rats, Sprague-Dawley ; Signal Transduction/drug effects ; Thiazoles/therapeutic use
Czasopismo naukowe
Tytuł:
Adipose-Derived Stromal Cells Attenuate Adipose Inflammation in Obesity through Adipocyte Browning and Polarization of M2 Macrophages.
Autorzy:
Zhang WC; Division of Plastic and Reconstructive Surgery, Department of Plastic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100032, China.
Qin F; Division of Plastic and Reconstructive Surgery, Department of Plastic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100032, China.
Wang XJ; Division of Plastic and Reconstructive Surgery, Department of Plastic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100032, China.
Liu ZF; Division of Plastic and Reconstructive Surgery, Department of Plastic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100032, China.
Zhu L; Division of Plastic and Reconstructive Surgery, Department of Plastic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100032, China.
Zeng A; Division of Plastic and Reconstructive Surgery, Department of Plastic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100032, China.
Zhang MZ; Division of Plastic and Reconstructive Surgery, Department of Plastic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100032, China.
Yu NZ; Division of Plastic and Reconstructive Surgery, Department of Plastic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100032, China.
Long X; Division of Plastic and Reconstructive Surgery, Department of Plastic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100032, China.
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Źródło:
Mediators of inflammation [Mediators Inflamm] 2019 Dec 04; Vol. 2019, pp. 1731540. Date of Electronic Publication: 2019 Dec 04 (Print Publication: 2019).
Typ publikacji:
Journal Article
MeSH Terms:
Adipocytes/*drug effects
Inflammation/*metabolism
Macrophages/*immunology
Macrophages/*metabolism
Obesity/*immunology
Obesity/*metabolism
Adiposity/genetics ; Adiposity/physiology ; Animals ; Blotting, Western ; Female ; Flow Cytometry ; Interleukin-10/metabolism ; Interleukin-1beta/metabolism ; Interleukin-6/metabolism ; Male ; Mice ; Random Allocation ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł:
miR-221 Alleviates the Ox-LDL-Induced Macrophage Inflammatory Response via the Inhibition of DNMT3b-Mediated NCoR Promoter Methylation.
Autorzy:
Ye J; Department of Cardiology, 920 Hospital of PLA Joint Logistic Support Force, Yunnan 650032, China.; Department of Cardiology, Tongren Hospital, Yunnan 650032, China.
Wu Y; Institution of Cardiovascular Research, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China.
Guo R; Department of Cardiology, 920 Hospital of PLA Joint Logistic Support Force, Yunnan 650032, China.
Zeng W; Department of Cardiology, Tongren Hospital, Yunnan 650032, China.
Duan Y; Department of Cardiology, Tongren Hospital, Yunnan 650032, China.
Yang Z; Department of Cardiology, Tongren Hospital, Yunnan 650032, China.
Yang L; Department of Cardiology, 920 Hospital of PLA Joint Logistic Support Force, Yunnan 650032, China.
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Źródło:
Mediators of inflammation [Mediators Inflamm] 2019 Sep 03; Vol. 2019, pp. 4530534. Date of Electronic Publication: 2019 Sep 03 (Print Publication: 2019).
Typ publikacji:
Journal Article
MeSH Terms:
Inflammation/*metabolism
Lipoproteins, LDL/*metabolism
Macrophages/*metabolism
MicroRNAs/*metabolism
Blotting, Western ; DNA (Cytosine-5-)-Methyltransferases/metabolism ; HEK293 Cells ; Humans ; Interleukin-6/metabolism ; Promoter Regions, Genetic/genetics ; Real-Time Polymerase Chain Reaction ; THP-1 Cells ; Tumor Necrosis Factor-alpha/metabolism ; DNA Methyltransferase 3B
Czasopismo naukowe
Tytuł:
On the use of abiotic sialic acids to attenuate cell inflammation.
Autorzy:
Xue Z; Department of Chemical Biology, College of Chemistry and Chemical Engineering, State Key Laboratory for Physical Chemistry of Solid Surfaces, the Key Laboratory for Chemical Biology of Fujian Province, The MOE Key Laboratory of Spectrochemical Analysis & Instrumentation, and Innovation Center for Cell Biology, Xiamen University, Xiamen, 361005, China.
Zhao H; Department of Chemical Biology, College of Chemistry and Chemical Engineering, State Key Laboratory for Physical Chemistry of Solid Surfaces, the Key Laboratory for Chemical Biology of Fujian Province, The MOE Key Laboratory of Spectrochemical Analysis & Instrumentation, and Innovation Center for Cell Biology, Xiamen University, Xiamen, 361005, China.
Zhu R; Department of Chemical Biology, College of Chemistry and Chemical Engineering, State Key Laboratory for Physical Chemistry of Solid Surfaces, the Key Laboratory for Chemical Biology of Fujian Province, The MOE Key Laboratory of Spectrochemical Analysis & Instrumentation, and Innovation Center for Cell Biology, Xiamen University, Xiamen, 361005, China.
Chen C; National Glycoengineering research center, Shandong University, Jinan, 250012, China.
Cao H; National Glycoengineering research center, Shandong University, Jinan, 250012, China.
Han J; State key Laboratory of Cellular Stress Biology, Innovation Center for Cell Biology, School of Life Sciences, Xiamen University, Xiamen, 361005, China.
Han S; Department of Chemical Biology, College of Chemistry and Chemical Engineering, State Key Laboratory for Physical Chemistry of Solid Surfaces, the Key Laboratory for Chemical Biology of Fujian Province, The MOE Key Laboratory of Spectrochemical Analysis & Instrumentation, and Innovation Center for Cell Biology, Xiamen University, Xiamen, 361005, China. .
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Źródło:
Scientific reports [Sci Rep] 2018 Nov 23; Vol. 8 (1), pp. 17320. Date of Electronic Publication: 2018 Nov 23.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Anti-Inflammatory Agents/*pharmacology
Gene Expression Regulation/*drug effects
Inflammation/*prevention & control
Macrophages/*drug effects
Mitogen-Activated Protein Kinases/*antagonists & inhibitors
NF-kappa B/*antagonists & inhibitors
Sialic Acids/*pharmacology
Animals ; Inflammation/metabolism ; Inflammation/pathology ; Interleukin-6/genetics ; Interleukin-6/metabolism ; Macrophages/immunology ; Macrophages/metabolism ; Macrophages/pathology ; Mice ; Phosphorylation ; RAW 264.7 Cells ; Signal Transduction ; Stress, Physiological
Czasopismo naukowe
Tytuł:
Anti-Inflammatory Effects of Aurantiochytrium limacinum 4W-1b Ethanol Extract on Murine Macrophage RAW264 Cells.
Autorzy:
Takahashi S; Faculty of Life and Environmental Sciences, University of Tsukuba, Tsukuba City 305-8572, Japan.; Master's/Doctoral Program in Life Science Innovation, School of Integrative and Global Majors (SIGMA), University of Tsukuba, Tsukuba City 305-8572, Japan.; Alliance for Research on the Mediterranean and North Africa (ARENA), University of Tsukuba, Tsukuba City 305-8572, Japan.
Yoshida M; Faculty of Life and Environmental Sciences, University of Tsukuba, Tsukuba City 305-8572, Japan.; Algae Biomass and Energy System R&D Center (ABES), University of Tsukuba, Tsukuba City 305-8572, Japan.
Watanabe MM; Faculty of Life and Environmental Sciences, University of Tsukuba, Tsukuba City 305-8572, Japan.; Algae Biomass and Energy System R&D Center (ABES), University of Tsukuba, Tsukuba City 305-8572, Japan.
Isoda H; Faculty of Life and Environmental Sciences, University of Tsukuba, Tsukuba City 305-8572, Japan.; Master's/Doctoral Program in Life Science Innovation, School of Integrative and Global Majors (SIGMA), University of Tsukuba, Tsukuba City 305-8572, Japan.; Alliance for Research on the Mediterranean and North Africa (ARENA), University of Tsukuba, Tsukuba City 305-8572, Japan.
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Źródło:
BioMed research international [Biomed Res Int] 2019 Jan 28; Vol. 2019, pp. 3104057. Date of Electronic Publication: 2019 Jan 28 (Print Publication: 2019).
Typ publikacji:
Journal Article
MeSH Terms:
Inflammation/*drug therapy
Macrophages/*drug effects
Plant Extracts/*pharmacology
Stramenopiles/*chemistry
Animals ; Ethanol/chemistry ; Gene Expression Regulation/drug effects ; Humans ; Inflammation/chemically induced ; Inflammation/pathology ; Interleukin-1beta/genetics ; Interleukin-6/genetics ; Lipopolysaccharides/toxicity ; Mice ; NF-kappa B/genetics ; Nitric Oxide/genetics ; Nitriles/pharmacology ; Plant Extracts/chemistry ; RAW 264.7 Cells ; Sulfones/pharmacology
Czasopismo naukowe
Tytuł:
Centella asiatica (L.) extract attenuates inflammation and improve insulin sensitivity in a coculture of lipopolysaccharide (LPS)-induced 3T3-L1 adipocytes and RAW 264.7 macrophages.
Autorzy:
Kusumastuti SA; Center of Pharmaceutical and Medicine Technology, Agency for the Assessment and Application of Technology (BPPT), Jakarta, Indonesia.
Nugrahaningsih DAA; Department of Pharmacology and Therapy, Medical Faculty, Universitas Gadjah Mada, Yogyakarta, Indonesia.
Wahyuningsih MSH; Department of Pharmacology and Therapy, Medical Faculty, Universitas Gadjah Mada, Yogyakarta, Indonesia.
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Źródło:
Drug discoveries & therapeutics [Drug Discov Ther] 2019; Vol. 13 (5), pp. 261-267.
Typ publikacji:
Journal Article
MeSH Terms:
Insulin Resistance*
Adipocytes/*drug effects
Inflammation/*prevention & control
Macrophages/*drug effects
Triterpenes/*pharmacology
Adipocytes/metabolism ; Animals ; Anti-Inflammatory Agents/pharmacology ; Centella ; Coculture Techniques ; Glucose/metabolism ; Glucose Transporter Type 4/biosynthesis ; Inflammation/chemically induced ; Insulin Receptor Substrate Proteins/biosynthesis ; Interleukin-6/biosynthesis ; Lipopolysaccharides ; Macrophages/metabolism ; Mice ; Plant Extracts
Czasopismo naukowe
Tytuł:
Ferulic acid but not alpha-lipoic acid effectively protects THP-1-derived macrophages from oxidant and pro-inflammatory response to LPS.
Autorzy:
Szulc-Kielbik I; a Institute of Medical Biology , Polish Academy of Sciences , Lodz , Poland.
Kielbik M; a Institute of Medical Biology , Polish Academy of Sciences , Lodz , Poland.
Klink M; b Faculty of Cosmetology , The Academy of Cosmetics and Health Care , Warsaw , Poland.
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Źródło:
Immunopharmacology and immunotoxicology [Immunopharmacol Immunotoxicol] 2017 Dec; Vol. 39 (6), pp. 330-337. Date of Electronic Publication: 2017 Sep 05.
Typ publikacji:
Journal Article
MeSH Terms:
Anti-Inflammatory Agents/*pharmacology
Coumaric Acids/*pharmacology
Inflammation/*drug therapy
Macrophages/*drug effects
Oxidants/*metabolism
Thioctic Acid/*pharmacology
Antioxidants/pharmacology ; Biphenyl Compounds/pharmacology ; Cell Line ; Free Radical Scavengers/pharmacology ; Humans ; Inflammation/chemically induced ; Inflammation/metabolism ; Interleukin-1beta/metabolism ; Interleukin-6/metabolism ; Lipopolysaccharides/pharmacology ; Macrophages/metabolism ; Picrates/pharmacology ; Reactive Oxygen Species/metabolism ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł:
Antioxidant, anti-inflammatory and anti-septic potential of phenolic acids and flavonoid fractions isolated from Lolium multiflorum.
Autorzy:
Choi KC; a Grassland and Forages Research Center , National Institute of Animal Science , Cheonan , South Korea.
Son YO; b Cell Dynamics Research Center and School of Life Sciences , Gwangju Institute of Science and Technology , Gwangju , South Korea.
Hwang JM; c Research Center of Bioactive Materials , Chonbuk National University , Jeonju , South Korea.
Kim BT; c Research Center of Bioactive Materials , Chonbuk National University , Jeonju , South Korea.
Chae M; c Research Center of Bioactive Materials , Chonbuk National University , Jeonju , South Korea.
Lee JC; c Research Center of Bioactive Materials , Chonbuk National University , Jeonju , South Korea.; d Institute of Oral Biosciences and School of Dentistry , Chonbuk National University , Jeonju , South Korea.
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Źródło:
Pharmaceutical biology [Pharm Biol] 2017 Dec; Vol. 55 (1), pp. 611-619.
Typ publikacji:
Journal Article
MeSH Terms:
Anti-Infective Agents, Local/*pharmacology
Anti-Inflammatory Agents/*pharmacology
Antioxidants/*pharmacology
Flavonoids/*pharmacology
Hydroxybenzoates/*pharmacology
Inflammation/*prevention & control
Lolium/*chemistry
Macrophages/*drug effects
Plant Extracts/*pharmacology
Sepsis/*prevention & control
Animals ; Anti-Infective Agents, Local/isolation & purification ; Anti-Inflammatory Agents/isolation & purification ; Antioxidants/isolation & purification ; Chromatography, High Pressure Liquid ; Disease Models, Animal ; Female ; Flavonoids/isolation & purification ; Hydroxybenzoates/isolation & purification ; Inflammation/chemically induced ; Inflammation/metabolism ; Inflammation Mediators/metabolism ; Interleukin-6/metabolism ; Lipopolysaccharides ; Macrophages/metabolism ; Mice ; Mice, Inbred BALB C ; Mice, Inbred ICR ; Mitogen-Activated Protein Kinases/metabolism ; NF-kappa B/metabolism ; Nitric Oxide/metabolism ; Oxidative Stress/drug effects ; Phytotherapy ; Plant Extracts/isolation & purification ; Plants, Medicinal ; RAW 264.7 Cells ; Sepsis/chemically induced ; Sepsis/metabolism ; Silage ; Solvents/chemistry ; Time Factors ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł:
Para-hydroxyphenylpyruvate inhibits the pro-inflammatory stimulation of macrophage preventing LPS-mediated nitro-oxidative unbalance and immunometabolic shift.
Autorzy:
Scrima R; Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy.
Menga M; Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy.
Pacelli C; Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy.
Agriesti F; Laboratory of Pre-Clinical and Translational Research, IRCCS CROB, Rionero in Vulture, Potenza, Italy.
Cela O; Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy.
Piccoli C; Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy.
Cotoia A; Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy.
De Gregorio A; Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy.
Gefter JV; Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, United States of America.
Cinnella G; Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy.
Capitanio N; Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy.
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Źródło:
PloS one [PLoS One] 2017 Nov 27; Vol. 12 (11), pp. e0188683. Date of Electronic Publication: 2017 Nov 27 (Print Publication: 2017).
Typ publikacji:
Journal Article
MeSH Terms:
Inflammation/*immunology
Inflammation/*metabolism
Lipopolysaccharides/*pharmacology
Macrophages/*immunology
Macrophages/*metabolism
Animals ; Anti-Inflammatory Agents/pharmacology ; Cell Respiration/drug effects ; Fibroblasts/drug effects ; Fibroblasts/metabolism ; Humans ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism ; Inflammation/pathology ; Interleukin-6/metabolism ; Macrophages/drug effects ; Metabolic Flux Analysis ; Mice ; Mitochondria/drug effects ; Mitochondria/metabolism ; Models, Biological ; Nitrates/metabolism ; Nitric Oxide/biosynthesis ; Nitric Oxide Synthase Type II/metabolism ; Nitrites/metabolism ; Nitrosation ; Oxidation-Reduction ; Peroxides/metabolism ; Phenylpyruvic Acids/chemistry ; Phenylpyruvic Acids/pharmacology ; Pyruvates/chemistry ; Pyruvates/pharmacology ; RAW 264.7 Cells
Czasopismo naukowe
Tytuł:
Regulation of Leukocyte Recruitment to the Spleen and Peritoneal Cavity during Pristane-Induced Inflammation.
Autorzy:
Li Y; Department of Basic Medicine, Haihe Clinical College of Tianjin Medical University, Tianjin, China.
Wu J; Key Research Laboratory for Infectious Disease Prevention for State Administration of Traditional Chinese Medicine, Tianjin Institute of Respiratory Diseases, Tianjin Haihe Hospital, Tianjin 300350, China.; Department of Respiratory Medicine, Tianjin Haihe Hospital, Tianjin 300350, China.
Xu L; Key Research Laboratory for Infectious Disease Prevention for State Administration of Traditional Chinese Medicine, Tianjin Institute of Respiratory Diseases, Tianjin Haihe Hospital, Tianjin 300350, China.
Wu Q; Key Research Laboratory for Infectious Disease Prevention for State Administration of Traditional Chinese Medicine, Tianjin Institute of Respiratory Diseases, Tianjin Haihe Hospital, Tianjin 300350, China.
Wan Z; Department of Basic Medicine, Haihe Clinical College of Tianjin Medical University, Tianjin, China.
Li L; Department of Respiratory Medicine, Tianjin Haihe Hospital, Tianjin 300350, China.
Yu H; Department of Respiratory Medicine, Tianjin Haihe Hospital, Tianjin 300350, China.
Li X; Department of Basic Medicine, Haihe Clinical College of Tianjin Medical University, Tianjin, China.
Li K; Department of Basic Medicine, Haihe Clinical College of Tianjin Medical University, Tianjin, China.
Zhang Q; Department of Basic Medicine, Haihe Clinical College of Tianjin Medical University, Tianjin, China.
Hou Z; Department of Tuberculosis, Tianjin Haihe Hospital, Tianjin 300350, China.
Sun X; Department of Basic Medicine, Haihe Clinical College of Tianjin Medical University, Tianjin, China.; Key Research Laboratory for Infectious Disease Prevention for State Administration of Traditional Chinese Medicine, Tianjin Institute of Respiratory Diseases, Tianjin Haihe Hospital, Tianjin 300350, China.
Chen H; Department of Basic Medicine, Haihe Clinical College of Tianjin Medical University, Tianjin, China.
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Źródło:
Journal of immunology research [J Immunol Res] 2017; Vol. 2017, pp. 9891348. Date of Electronic Publication: 2017 Oct 19.
Typ publikacji:
Journal Article
MeSH Terms:
Inflammation/*immunology
Macrophages/*immunology
Neutrophils/*immunology
Peritoneal Cavity/*pathology
Spleen/*immunology
Animals ; Cell Movement ; Cell Separation ; Flow Cytometry ; Inflammation/chemically induced ; Interleukin-6/genetics ; Interleukin-6/metabolism ; Lymphotoxin-alpha/genetics ; Lymphotoxin-alpha/metabolism ; Mice ; Mice, Knockout ; Terpenes ; Tumor Necrosis Factor-alpha/genetics ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł:
Uprolides N, O and P from the Panamanian Octocoral Eunicea succinea.
Autorzy:
Torres-Mendoza D; Center for Biodiversity and Drug Discovery, Institute for Scientific Research and Technology Services (INDICASAT), Clayton, City of Knowledge 0843-01103, Panama. .; Department of Biotechnology, Acharya Nagarjuna University, Nagarjuna Nagar, Guntur 522510, India. .
González Y; Department of Biotechnology, Acharya Nagarjuna University, Nagarjuna Nagar, Guntur 522510, India. .; Center for Molecular and Cellular Biology of Diseases, Institute for Scientific Research and Technology Services (INDICASAT), Clayton, City of Knowledge 0843-01103, Panama. .
Gómez-Reyes JF; Center for Biodiversity and Drug Discovery, Institute for Scientific Research and Technology Services (INDICASAT), Clayton, City of Knowledge 0843-01103, Panama. .
Guzmán HM; Smithsonian Tropical Research Institute, Balboa, Ancon 0843-03092, Panama. .
López-Perez JL; Department of Pharmaceutical Sciences, Faculty of Pharmacy, University of Salamanca, Ave. Campo Charro, s/n, Salamanca 37007, Spain. .
Gerwick WH; Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography and The Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California at San Diego, La Jolla, CA 92037, USA. .
Fernandez PL; Center for Molecular and Cellular Biology of Diseases, Institute for Scientific Research and Technology Services (INDICASAT), Clayton, City of Knowledge 0843-01103, Panama. .
Gutiérrez M; Center for Biodiversity and Drug Discovery, Institute for Scientific Research and Technology Services (INDICASAT), Clayton, City of Knowledge 0843-01103, Panama. .
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2016 Jun 22; Vol. 21 (6). Date of Electronic Publication: 2016 Jun 22.
Typ publikacji:
Journal Article
MeSH Terms:
Anthozoa/*chemistry
Diterpenes/*chemistry
Inflammation/*drug therapy
Macrophages/*drug effects
Animals ; Diterpenes/administration & dosage ; Diterpenes/isolation & purification ; Gene Expression Regulation/drug effects ; Inflammation/chemically induced ; Inflammation/genetics ; Interleukin-6/biosynthesis ; Interleukin-6/genetics ; Magnetic Resonance Spectroscopy ; Mass Spectrometry ; Models, Molecular ; Panama ; Plant Extracts/chemistry ; Tumor Cells, Cultured ; Tumor Necrosis Factor-alpha/biosynthesis ; Tumor Necrosis Factor-alpha/genetics
Czasopismo naukowe
Tytuł:
Ascofuranone inhibits lipopolysaccharide-induced inflammatory response via NF-kappaB and AP-1, p-ERK, TNF-α, IL-6 and IL-1β in RAW 264.7 macrophages.
Autorzy:
Park JY; Molecular and Cellular Glycobiology Unit, Department of Biological Sciences, SungKyunKwan University, Seoburo 2066, Jangan-Gu, Suwon, Gyunggi-Do, Korea.
Chung TW; School of Korean Medicine and Healthy Aging Korean Medicine Research Center, Pusan National University, Yangsan City, Gyeongsangnam-Do, Republic of Korea.
Jeong YJ; Research Institute of Biomedical Engineering and Department of Medicine, Catholic University of Daegu School of Medicine, Daegu, Republic of Korea.
Kwak CH; Molecular and Cellular Glycobiology Unit, Department of Biological Sciences, SungKyunKwan University, Seoburo 2066, Jangan-Gu, Suwon, Gyunggi-Do, Korea.
Ha SH; Molecular and Cellular Glycobiology Unit, Department of Biological Sciences, SungKyunKwan University, Seoburo 2066, Jangan-Gu, Suwon, Gyunggi-Do, Korea.
Kwon KM; Molecular and Cellular Glycobiology Unit, Department of Biological Sciences, SungKyunKwan University, Seoburo 2066, Jangan-Gu, Suwon, Gyunggi-Do, Korea.
Abekura F; Molecular and Cellular Glycobiology Unit, Department of Biological Sciences, SungKyunKwan University, Seoburo 2066, Jangan-Gu, Suwon, Gyunggi-Do, Korea.
Cho SH; Division of Enteric Diseases, Center for Infectious Diseases Research, Korea National Institute of Health, Heungdeok-gu, Cheongju, Korea.
Lee YC; Faculty of Medicinal Biotechnology, Dong-A University, Busan, Republic of Korea.
Ha KT; School of Korean Medicine and Healthy Aging Korean Medicine Research Center, Pusan National University, Yangsan City, Gyeongsangnam-Do, Republic of Korea.
Magae J; Magae Bioscience Institute, 49-4 Fujimidai, Tsukuba, Japan.
Chang YC; Research Institute of Biomedical Engineering and Department of Medicine, Catholic University of Daegu School of Medicine, Daegu, Republic of Korea.
Kim CH; Molecular and Cellular Glycobiology Unit, Department of Biological Sciences, SungKyunKwan University, Seoburo 2066, Jangan-Gu, Suwon, Gyunggi-Do, Korea.; Samsung Advanced Institute for Health Sciences & Technology (SAIHST), Sungkyunkwan University, Seoul, South Korea.
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Źródło:
PloS one [PLoS One] 2017 Feb 16; Vol. 12 (2), pp. e0171322. Date of Electronic Publication: 2017 Feb 16 (Print Publication: 2017).
Typ publikacji:
Journal Article
MeSH Terms:
Anti-Inflammatory Agents/*pharmacology
Inflammation/*drug therapy
Inflammation Mediators/*metabolism
Macrophages/*drug effects
Sesquiterpenes/*pharmacology
Animals ; Cells, Cultured ; Extracellular Signal-Regulated MAP Kinases/metabolism ; Inflammation/chemically induced ; Inflammation/metabolism ; Interleukin-1beta/metabolism ; Interleukin-6/metabolism ; Lipopolysaccharides/toxicity ; Macrophages/cytology ; Macrophages/metabolism ; Mice ; NF-kappa B/metabolism ; Phosphorylation/drug effects ; Signal Transduction/drug effects ; Transcription Factor AP-1/metabolism ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł:
Intrinsic Properties of Brown and White Adipocytes Have Differential Effects on Macrophage Inflammatory Responses.
Autorzy:
Dowal L; Berg LLC, Framingham, MA, USA.
Parameswaran P; Berg LLC, Framingham, MA, USA.
Phat S; Berg LLC, Framingham, MA, USA.
Akella S; Berg LLC, Framingham, MA, USA.
Majumdar ID; Berg LLC, Framingham, MA, USA.
Ranjan J; Berg LLC, Framingham, MA, USA.
Shah C; Berg LLC, Framingham, MA, USA.
Mogre S; Berg LLC, Framingham, MA, USA.
Guntur K; Berg LLC, Framingham, MA, USA.
Thapa K; Berg LLC, Framingham, MA, USA.
Gesta S; Berg LLC, Framingham, MA, USA.
Vishnudas VK; Berg LLC, Framingham, MA, USA.
Narain NR; Berg LLC, Framingham, MA, USA.
Sarangarajan R; Berg LLC, Framingham, MA, USA.
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Źródło:
Mediators of inflammation [Mediators Inflamm] 2017; Vol. 2017, pp. 9067049. Date of Electronic Publication: 2017 Mar 26.
Typ publikacji:
Journal Article
MeSH Terms:
Adipocytes, Brown/*metabolism
Adipocytes, White/*metabolism
Inflammation/*metabolism
Macrophages/*metabolism
Adipocytes, Brown/drug effects ; Adipocytes, Brown/immunology ; Adipocytes, White/drug effects ; Adipocytes, White/immunology ; Adult ; Cell Differentiation/drug effects ; Cell Line ; Cells, Cultured ; Enzyme-Linked Immunosorbent Assay ; Female ; Gene Expression Profiling ; Humans ; Inflammation/immunology ; Interleukin-4/pharmacology ; Interleukin-6/metabolism ; Lipopolysaccharides/pharmacology ; Macrophages/drug effects ; Macrophages/immunology ; Middle Aged
Czasopismo naukowe
Tytuł:
Differences in Proinflammatory Property of Six Subtypes of Peroxiredoxins and Anti-Inflammatory Effect of Ligustilide in Macrophages.
Autorzy:
Zhao LX; Department of Pharmacology, Key Laboratory of Drug Targeting and Drug Delivery Systems, West China School of Pharmacy, Sichuan University, Chengdu, China.
Du JR; Department of Pharmacology, Key Laboratory of Drug Targeting and Drug Delivery Systems, West China School of Pharmacy, Sichuan University, Chengdu, China.
Zhou HJ; Department of Pharmacology, Key Laboratory of Drug Targeting and Drug Delivery Systems, West China School of Pharmacy, Sichuan University, Chengdu, China.
Liu DL; Department of Pharmacology, Key Laboratory of Drug Targeting and Drug Delivery Systems, West China School of Pharmacy, Sichuan University, Chengdu, China.
Gu MX; Department of Pharmacology, Key Laboratory of Drug Targeting and Drug Delivery Systems, West China School of Pharmacy, Sichuan University, Chengdu, China.
Long FY; Department of Pharmacology, Key Laboratory of Drug Targeting and Drug Delivery Systems, West China School of Pharmacy, Sichuan University, Chengdu, China.
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Źródło:
PloS one [PLoS One] 2016 Oct 07; Vol. 11 (10), pp. e0164586. Date of Electronic Publication: 2016 Oct 07 (Print Publication: 2016).
Typ publikacji:
Journal Article
MeSH Terms:
4-Butyrolactone/*analogs & derivatives
Anti-Inflammatory Agents/*metabolism
Inflammation/*metabolism
Macrophages/*metabolism
Peroxiredoxins/*metabolism
4-Butyrolactone/metabolism ; Animals ; Cell Line ; Interleukin-6/metabolism ; Mice ; NF-kappa B/metabolism ; Nitric Oxide/metabolism ; Nitric Oxide Synthase Type II/metabolism ; Signal Transduction/physiology ; Toll-Like Receptor 4/metabolism ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł:
Rice bran prevents high-fat diet-induced inflammation and macrophage content in adipose tissue.
Autorzy:
Justo ML; Department of Pharmacology, School of Pharmacy, University of Seville, C/Profesor Garcia-Gonzalez 2, 41012, Seville, Spain.
Claro C; Department of Pharmacology, School of Pharmacy, University of Seville, C/Profesor Garcia-Gonzalez 2, 41012, Seville, Spain.
Zeyda M; Christian Doppler Laboratory for Cardio-Metabolic Immunotherapy and Clinical Division for Endocrinology and Metabolism, Department of Medicine III, Medical University Vienna, 1090, Vienna, Austria.
Stulnig TM; Christian Doppler Laboratory for Cardio-Metabolic Immunotherapy and Clinical Division for Endocrinology and Metabolism, Department of Medicine III, Medical University Vienna, 1090, Vienna, Austria.
Herrera MD; Department of Pharmacology, School of Pharmacy, University of Seville, C/Profesor Garcia-Gonzalez 2, 41012, Seville, Spain.
Rodríguez-Rodríguez R; Department of Pharmacology, School of Pharmacy, University of Seville, C/Profesor Garcia-Gonzalez 2, 41012, Seville, Spain. .; Department of Health Sciences, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya (UiC), Sant Cugat del Vallés, Spain. .; Basic Sciences Department, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya (UiC), Josep Trueta s/n, 08195, Sant Cugat del Vallés, Barcelona, Spain. .
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Źródło:
European journal of nutrition [Eur J Nutr] 2016 Sep; Vol. 55 (6), pp. 2011-9. Date of Electronic Publication: 2015 Aug 13.
Typ publikacji:
Journal Article
MeSH Terms:
Adipose Tissue, White/*metabolism
Diet, High-Fat/*adverse effects
Dietary Fiber/*administration & dosage
Inflammation/*diet therapy
Macrophages/*metabolism
Oryza/*chemistry
Adipocytes ; Adiponectin/metabolism ; Animals ; Biomarkers/blood ; Calcium-Binding Proteins ; Cholesterol/blood ; Dyslipidemias/diet therapy ; Dyslipidemias/etiology ; Inflammation/etiology ; Insulin/blood ; Insulin Resistance ; Interleukin-1beta/blood ; Interleukin-6/blood ; Male ; Mice ; Mice, Inbred C57BL ; Obesity/diet therapy ; Obesity/etiology ; PPAR gamma/metabolism ; Receptors, Cell Surface/metabolism ; Receptors, G-Protein-Coupled ; Triglycerides/blood ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe

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