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Wyszukujesz frazę ""Intestinal absorption"" wg kryterium: Temat


Tytuł :
Novel Case Report: A Previously Reported, but Pathophysiologically Unexplained, Association Between Collagenous Colitis and Protein-Losing Enteropathy May Be Explained by an Undetected Link with Collagenous Duodenitis.
Autorzy :
Gill I; Division of Gastroenterology, Department of Internal Medicine, William Beaumont Hospital at Royal Oak, 3535 W. Thirteen Mile Rd, Royal Oak, MI, 48073, USA.
Shaheen AA; Division of Gastroenterology, Department of Internal Medicine, William Beaumont Hospital at Royal Oak, 3535 W. Thirteen Mile Rd, Royal Oak, MI, 48073, USA.
Edhi AI; Division of Gastroenterology, Department of Internal Medicine, William Beaumont Hospital at Royal Oak, 3535 W. Thirteen Mile Rd, Royal Oak, MI, 48073, USA.
Amin M; Department of Pathology, William Beaumont Hospital at Royal Oak, 3600 W. Thirteen Mile Rd, Royal Oak, MI, 48073, USA.; Department of Pathology, Oakland University William Beaumont School of Medicine, 3600 W. Thirteen Mile Rd, Royal Oak, MI, 48073, USA.
Rana K; Division of Gastroenterology, Department of Internal Medicine, William Beaumont Hospital at Royal Oak, 3535 W. Thirteen Mile Rd, Royal Oak, MI, 48073, USA.
Cappell MS; Division of Gastroenterology, Department of Internal Medicine, William Beaumont Hospital at Royal Oak, 3535 W. Thirteen Mile Rd, Royal Oak, MI, 48073, USA. .; Division of Gastroenterology, Department of Internal Medicine, Oakland University William Beaumont School of Medicine, 3535 W. Thirteen Mile Rd, Royal Oak, MI, 48073, USA. .
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Źródło :
Digestive diseases and sciences [Dig Dis Sci] 2021 Dec; Vol. 66 (12), pp. 4557-4564. Date of Electronic Publication: 2021 Feb 04.
Typ publikacji :
Case Reports
MeSH Terms :
Intestinal Absorption*
Amino Acids/*metabolism
COVID-19/*etiology
Colitis, Collagenous/*complications
Duodenitis/*complications
Duodenum/*physiopathology
Intestinal Mucosa/*physiopathology
Protein-Losing Enteropathies/*etiology
Aged ; COVID-19/diagnosis ; COVID-19/drug therapy ; COVID-19/physiopathology ; Colitis, Collagenous/diagnosis ; Colitis, Collagenous/physiopathology ; Colitis, Collagenous/therapy ; Duodenitis/diagnosis ; Duodenitis/physiopathology ; Duodenitis/therapy ; Duodenum/metabolism ; Female ; Fluid Therapy ; Glucocorticoids/therapeutic use ; Humans ; Intestinal Mucosa/metabolism ; Nutritional Status ; Parenteral Nutrition, Total ; Protein-Losing Enteropathies/diagnosis ; Protein-Losing Enteropathies/physiopathology ; Protein-Losing Enteropathies/therapy ; Risk Factors ; Treatment Outcome
SCR Protocol :
COVID-19 drug treatment
Raport
Tytuł :
Dual effects of quercetin on protein digestion and absorption in the digestive tract.
Autorzy :
Cheng Y; College of Chemistry, National & Local Joint Biomedical Engineering Research Center on Photodynamic Technologies, Fuzhou University, Fuzhou, China.
Liu Y; College of Chemistry, National & Local Joint Biomedical Engineering Research Center on Photodynamic Technologies, Fuzhou University, Fuzhou, China.
Chen D; College of Chemistry, National & Local Joint Biomedical Engineering Research Center on Photodynamic Technologies, Fuzhou University, Fuzhou, China.
Zhou Y; College of Chemistry, National & Local Joint Biomedical Engineering Research Center on Photodynamic Technologies, Fuzhou University, Fuzhou, China.
Yu S; College of Chemistry, National & Local Joint Biomedical Engineering Research Center on Photodynamic Technologies, Fuzhou University, Fuzhou, China.
Lin H; College of Chemistry, National & Local Joint Biomedical Engineering Research Center on Photodynamic Technologies, Fuzhou University, Fuzhou, China.
Liao CK; Department of Chemistry, Columbia University, NY, USA.
Lin H; Department of Pharmacy, The Peoples Hospital of Fujian Province, Fuzhou, China.
Xu P; College of Biological Science and Engineering, National & Local Joint Biomedical Engineering Research Center on Photodynamic Technologies, Fuzhou University, Fuzhou, China; Fujian Key Laboratory of Marine Enzyme Engineering, Fuzhou University, Fuzhou, China. Electronic address: .
Huang M; College of Chemistry, National & Local Joint Biomedical Engineering Research Center on Photodynamic Technologies, Fuzhou University, Fuzhou, China; College of Biological Science and Engineering, National & Local Joint Biomedical Engineering Research Center on Photodynamic Technologies, Fuzhou University, Fuzhou, China; Fujian Key Laboratory of Marine Enzyme Engineering, Fuzhou University, Fuzhou, China. Electronic address: .
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Źródło :
Food chemistry [Food Chem] 2021 Oct 01; Vol. 358, pp. 129891. Date of Electronic Publication: 2021 Apr 20.
Typ publikacji :
Journal Article
MeSH Terms :
Dietary Proteins/*pharmacokinetics
Intestinal Absorption/*drug effects
Quercetin/*pharmacology
Animals ; Body Fluids/drug effects ; Body Fluids/metabolism ; Dietary Proteins/metabolism ; Digestion/drug effects ; Dogs ; Flavonoids/pharmacology ; Intestinal Absorption/physiology ; Intestinal Mucosa/drug effects ; Intestinal Mucosa/metabolism ; Madin Darby Canine Kidney Cells ; Male ; Permeability ; Proteolysis ; Rats, Sprague-Dawley ; Trypsin/metabolism ; Trypsin Inhibitors/pharmacology
Czasopismo naukowe
Tytuł :
Prediction of permeability across intestinal cell monolayers for 219 disparate chemicals using in vitro experimental coefficients in a pH gradient system and in silico analyses by trivariate linear regressions and machine learning.
Autorzy :
Kamiya Y; Laboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, 3-3165 Higashi-tamagawa Gakuen, Machida, Tokyo 194-8543, Japan.
Omura A; Laboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, 3-3165 Higashi-tamagawa Gakuen, Machida, Tokyo 194-8543, Japan.
Hayasaka R; Laboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, 3-3165 Higashi-tamagawa Gakuen, Machida, Tokyo 194-8543, Japan.
Saito R; Laboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, 3-3165 Higashi-tamagawa Gakuen, Machida, Tokyo 194-8543, Japan.
Sano I; Laboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, 3-3165 Higashi-tamagawa Gakuen, Machida, Tokyo 194-8543, Japan.
Handa K; Fujitsu, Nakahara-ku, Kawasaki 211-8588, Japan.
Ohori J; Fujitsu, Nakahara-ku, Kawasaki 211-8588, Japan.
Kitajima M; Fujitsu, Nakahara-ku, Kawasaki 211-8588, Japan.
Shono F; Data Science Center Tokyo Office, Nara Institute of Science and Technology, Minato-ku, Tokyo 108-0023, Japan.
Funatsu K; Data Science Center Tokyo Office, Nara Institute of Science and Technology, Minato-ku, Tokyo 108-0023, Japan.
Yamazaki H; Laboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, 3-3165 Higashi-tamagawa Gakuen, Machida, Tokyo 194-8543, Japan. Electronic address: .
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Źródło :
Biochemical pharmacology [Biochem Pharmacol] 2021 Oct; Vol. 192, pp. 114749. Date of Electronic Publication: 2021 Aug 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Computer Simulation*
Machine Learning*
Cell Membrane Permeability/*physiology
Inorganic Chemicals/*metabolism
Intestinal Absorption/*physiology
Caco-2 Cells ; Cell Membrane Permeability/drug effects ; Forecasting ; Humans ; Inorganic Chemicals/pharmacology ; Intestinal Absorption/drug effects ; Linear Models
Czasopismo naukowe
Tytuł :
Intestinal Phosphorus Absorption in Moderate CKD and Healthy Adults Determined Using a Radioisotopic Tracer.
Autorzy :
Stremke ER; Department of Nutrition Science, Purdue University, West Lafayette, Indiana.; Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, Minnesota.
Wiese GN; Department of Nutrition Science, Purdue University, West Lafayette, Indiana.
Moe SM; Division of Nephrology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana.; Department of Medicine, Roudebush Veterans Administration Medical Center, Indianapolis, Indiana.
Wastney ME; Department of Nutrition Science, Purdue University, West Lafayette, Indiana.; Metabolic Modeling Services, West Lafayette, Indiana.
Moorthi RN; Division of Nephrology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana.
Hill Gallant KM; Department of Nutrition Science, Purdue University, West Lafayette, Indiana .; Division of Nephrology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana.; Department of Food Science and Nutrition, University of Minnesota, St. Paul, Minnesota.
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Źródło :
Journal of the American Society of Nephrology : JASN [J Am Soc Nephrol] 2021 Aug; Vol. 32 (8), pp. 2057-2069. Date of Electronic Publication: 2021 Jul 08.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Intestinal Absorption*
Phosphorus/*metabolism
Renal Insufficiency, Chronic/*physiopathology
Adult ; Aged ; Case-Control Studies ; Female ; Fibroblast Growth Factors/blood ; Glomerular Filtration Rate ; Humans ; Male ; Middle Aged ; Parathyroid Hormone/blood ; Phosphorus/urine ; Phosphorus Radioisotopes ; Radioactive Tracers ; Renal Insufficiency, Chronic/blood ; Vitamin D/analogs & derivatives ; Vitamin D/blood
Czasopismo naukowe
Tytuł :
New Nanocarrier System for Liposomes Coated with Lactobacillus acidophilus S-Layer Protein to Improve Leu-Gln-Pro-Glu Absorption through the Intestinal Epithelium.
Autorzy :
Jiang X; Department of Food Science and Technology, School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, Nanjing 210023, Jiangsu, China.
Pan D; College of Food and Pharmaceutical Sciences, Ningbo University, Ningbo 315211, Zhejiang, P. R. China.
Tao M; Department of Food Science and Technology, School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, Nanjing 210023, Jiangsu, China.
Zhang T; Department of Food Science and Technology, School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, Nanjing 210023, Jiangsu, China.
Zeng X; College of Food and Pharmaceutical Sciences, Ningbo University, Ningbo 315211, Zhejiang, P. R. China.
Wu Z; College of Food and Pharmaceutical Sciences, Ningbo University, Ningbo 315211, Zhejiang, P. R. China.
Guo Y; Department of Food Science and Technology, School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, Nanjing 210023, Jiangsu, China.
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Źródło :
Journal of agricultural and food chemistry [J Agric Food Chem] 2021 Jul 14; Vol. 69 (27), pp. 7593-7602. Date of Electronic Publication: 2021 Jun 30.
Typ publikacji :
Journal Article
MeSH Terms :
Intestinal Absorption*
Lactobacillus acidophilus*
Liposomes*/metabolism
Peptides/*metabolism
Animals ; Intestinal Mucosa/metabolism ; Mice ; Particle Size
Czasopismo naukowe
Tytuł :
Oral epigallocatechin gallate reduces intestinal nadolol absorption via modulation of Oatp1a5 and Oct1 transcriptional levels in spontaneously hypertensive rats.
Autorzy :
Tan HJ; Faculty of Medicine and Health Sciences, Universiti Tunku Abdul Rahman, 43000 Kajang, Bandar Sungai Long, Selangor, Malaysia.
Ling WC; Faculty of Medicine and Health Sciences, Universiti Tunku Abdul Rahman, 43000 Kajang, Bandar Sungai Long, Selangor, Malaysia.
Chua AL; Faculty of Medicine, Universiti Teknologi Malaysia, Sungai Buloh, Selangor, Malaysia.
Lee SK; Faculty of Medicine and Health Sciences, Universiti Tunku Abdul Rahman, 43000 Kajang, Bandar Sungai Long, Selangor, Malaysia. Electronic address: .
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Źródło :
Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2021 Sep; Vol. 90, pp. 153623. Date of Electronic Publication: 2021 Jun 11.
Typ publikacji :
Journal Article
MeSH Terms :
Catechin*/analogs & derivatives
Catechin*/pharmacology
Intestinal Absorption*
Nadolol*/metabolism
Catecholamine Plasma Membrane Transport Proteins/*metabolism
Organic Anion Transporters, Sodium-Independent/*metabolism
Animals ; Male ; Rats ; Rats, Inbred SHR
Czasopismo naukowe
Tytuł :
No Correlation between Positive Fructose Hydrogen Breath Test and Clinical Symptoms in Children with Functional Gastrointestinal Disorders: A Retrospective Single-Centre Study.
Autorzy :
Kwiecień J; Department of Paediatrics, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, 41-800 Zabrze, Poland.
Hajzler W; Faculty of Medical Sciences in Zabrze, Doctoral School, Medical University of Silesia, 41-800 Zabrze, Poland.
Kosek K; Faculty of Medical Sciences in Zabrze, Students' Scientific Association of the Medical University in Silesia, 41-800 Zabrze, Poland.
Balcerowicz S; Clinical Hospital No 1 in Zabrze, Medical University of Silesia, 41-800 Zabrze, Poland.
Grzanka D; Faculty of Medical Sciences in Zabrze, Students' Scientific Association of the Medical University in Silesia, 41-800 Zabrze, Poland.
Gościniak W; Faculty of Medical Sciences in Zabrze, Students' Scientific Association of the Medical University in Silesia, 41-800 Zabrze, Poland.
Górowska-Kowolik K; Department of Paediatrics, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, 41-800 Zabrze, Poland.
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Źródło :
Nutrients [Nutrients] 2021 Aug 23; Vol. 13 (8). Date of Electronic Publication: 2021 Aug 23.
Typ publikacji :
Journal Article
MeSH Terms :
Breath Tests*
Intestinal Absorption*
Dietary Sugars/*adverse effects
Fructose/*adverse effects
Gastrointestinal Diseases/*etiology
Hydrogen/*analysis
Intestine, Small/*metabolism
Malabsorption Syndromes/*complications
Adolescent ; Age Factors ; Child ; Child, Preschool ; Dietary Sugars/metabolism ; Female ; Fructose/metabolism ; Gastrointestinal Diseases/diagnosis ; Gastrointestinal Diseases/metabolism ; Hospitalization ; Humans ; Malabsorption Syndromes/diagnosis ; Malabsorption Syndromes/metabolism ; Male ; Poland ; Predictive Value of Tests ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Evaluating the Impact of Physiological Properties of the Gastrointestinal Tract On Drug In Vivo Performance Using Physiologically Based Biopharmaceutics Modeling and Virtual Clinical Trials.
Autorzy :
Jereb R; University of Ljubljana, Faculty of Pharmacy, Aškerčeva cesta 7, 1000 Ljubljana, Slovenia; Lek Pharmaceuticals d.d., a Sandoz Company, Verovškova ulica 57, 1526 Ljubljana, Slovenia. Electronic address: .
Opara J; Lek Pharmaceuticals d.d., a Sandoz Company, Verovškova ulica 57, 1526 Ljubljana, Slovenia.
Bajc A; Lek Pharmaceuticals d.d., a Sandoz Company, Verovškova ulica 57, 1526 Ljubljana, Slovenia.
Petek B; Lek Pharmaceuticals d.d., a Sandoz Company, Verovškova ulica 57, 1526 Ljubljana, Slovenia.
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Źródło :
Journal of pharmaceutical sciences [J Pharm Sci] 2021 Aug; Vol. 110 (8), pp. 3069-3081. Date of Electronic Publication: 2021 Apr 18.
Typ publikacji :
Clinical Trial; Journal Article
MeSH Terms :
Biopharmaceutics*
Intestinal Absorption*
Administration, Oral ; Computer Simulation ; Gastrointestinal Tract/metabolism ; Humans ; Models, Biological ; Solubility ; Tablets/metabolism
Czasopismo naukowe
Tytuł :
Effect of Lanthanum Carbonate on Blood Pressure in CKD.
Autorzy :
Jamshidian MS; Department of Medicine, University of California San Diego, San Diego, CA. Electronic address: .
Larive B; Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH.
Gassman J; Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH.
Raphael KL; Division of Nephrology and Hypertension, University of Utah, Salt Lake City, UT.
Chonchol MB; Division of Renal Diseases and Hypertension, University of Anschutz Medical Center, Aurora, CO.
Ix JH; Division of Nephrology-Hypertension, University of California San Diego, San Diego, CA; Nephrology Section, Veterans Affairs San Diego Healthcare System, La Jolla, CA.
Ginsberg C; Division of Nephrology-Hypertension, University of California San Diego, San Diego, CA.
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Źródło :
American journal of kidney diseases : the official journal of the National Kidney Foundation [Am J Kidney Dis] 2021 Aug; Vol. 78 (2), pp. 312-314. Date of Electronic Publication: 2021 Jan 09.
Typ publikacji :
Letter; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Intestinal Absorption*
Antihypertensive Agents/*metabolism
Hypertension/*drug therapy
Lanthanum/*adverse effects
Phosphates/*metabolism
Renal Insufficiency, Chronic/*drug therapy
Aged ; Aged, 80 and over ; Antihypertensive Agents/therapeutic use ; Blood Pressure ; Drug Interactions ; Female ; Humans ; Hypertension/complications ; Hypertension/physiopathology ; Male ; Middle Aged ; Renal Insufficiency, Chronic/complications ; Renal Insufficiency, Chronic/metabolism
Raport
Tytuł :
Gastrointestinal Tolerance and Protein Absorption Markers with a New Peptide Enteral Formula Compared to a Standard Intact Protein Enteral Formula in Critically Ill Patients.
Autorzy :
de Brito-Ashurst I; Royal Brompton and Harefield NHS Foundation Trust, Royal Brompton Hospital, Sydney Street, London SW3 6NP, UK.; The Royal Marsden NHS Foundation Trust, Fulham Road, London SW3 6JJ, UK.
Klebach M; Danone Nutricia Research, Utrecht University, 3584 CT Utrecht, The Netherlands.
Tsompanaki E; Royal Brompton and Harefield NHS Foundation Trust, Royal Brompton Hospital, Sydney Street, London SW3 6NP, UK.; Imperial College Healthcare NHS Trust, St Mary's Hospital, London W2 1NY, UK.
Kaul S; Royal Brompton and Harefield NHS Foundation Trust, Royal Brompton Hospital, Sydney Street, London SW3 6NP, UK.
van Horssen P; Danone Nutricia Research, Utrecht University, 3584 CT Utrecht, The Netherlands.
Hofman Z; Danone Nutricia Research, Utrecht University, 3584 CT Utrecht, The Netherlands.
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Źródło :
Nutrients [Nutrients] 2021 Jul 10; Vol. 13 (7). Date of Electronic Publication: 2021 Jul 10.
Typ publikacji :
Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial
MeSH Terms :
Enteral Nutrition*/adverse effects
Food, Formulated*/adverse effects
Intestinal Absorption*
Nutritive Value*
Critical Illness/*therapy
Dietary Proteins/*administration & dosage
Protein Hydrolysates/*administration & dosage
Adult ; Aged ; Biomarkers/blood ; Biomarkers/urine ; Dietary Proteins/adverse effects ; Double-Blind Method ; Energy Intake ; Female ; Humans ; London ; Male ; Middle Aged ; Protein Hydrolysates/adverse effects ; Time Factors ; Treatment Outcome
Czasopismo naukowe
Tytuł :
In vitro models replicating the human intestinal epithelium for absorption and metabolism studies: A systematic review.
Autorzy :
Fedi A; Department of Computer Science, Bioengineering, Robotics and Systems Engineering, University of Genoa, 16126 Genoa, Italy; National Research Council of Italy, Institute of Electronics, Computer and Telecommunications (IEIIT) Institute, 16149 Genoa, Italy.
Vitale C; National Research Council of Italy, Institute of Electronics, Computer and Telecommunications (IEIIT) Institute, 16149 Genoa, Italy.
Ponschin G; Department of Computer Science, Bioengineering, Robotics and Systems Engineering, University of Genoa, 16126 Genoa, Italy.
Ayehunie S; MatTek Corporation, Ashland, MA, USA.
Fato M; Department of Computer Science, Bioengineering, Robotics and Systems Engineering, University of Genoa, 16126 Genoa, Italy; National Research Council of Italy, Institute of Electronics, Computer and Telecommunications (IEIIT) Institute, 16149 Genoa, Italy.
Scaglione S; National Research Council of Italy, Institute of Electronics, Computer and Telecommunications (IEIIT) Institute, 16149 Genoa, Italy. Electronic address: .
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Źródło :
Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 2021 Jul 10; Vol. 335, pp. 247-268. Date of Electronic Publication: 2021 May 24.
Typ publikacji :
Journal Article; Review; Systematic Review
MeSH Terms :
Intestinal Absorption*
Pharmaceutical Preparations*/metabolism
Animal Testing Alternatives ; Animals ; Biological Availability ; Humans ; Intestinal Mucosa/metabolism ; Intestines ; Models, Biological
Czasopismo naukowe
Tytuł :
Combining species specific in vitro & in silico models to predict in vivo food effect in a preclinical stage - case study of Venetoclax.
Autorzy :
Henze LJ; School of Pharmacy, University College Cork, Cork, Ireland.
Koehl NJ; Drug Product Development, Janssen Research and Development, Johnson & Johnson, Turnhoutseweg 30, 2340 Beerse, Belgium.
O'Shea JP; School of Pharmacy, University College Cork, Cork, Ireland.
Holm R; Drug Product Development, Janssen Research and Development, Johnson & Johnson, Turnhoutseweg 30, 2340 Beerse, Belgium; Department of Science and Environment, Roskilde University, 4000 Roskilde, Denmark.
Vertzoni M; Department of Pharmacy, School of Health Science, National and Kapodistrian University of Athens, Athens, Greece.
Griffin BT; School of Pharmacy, University College Cork, Cork, Ireland. Electronic address: .
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Źródło :
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences [Eur J Pharm Sci] 2021 Jul 01; Vol. 162, pp. 105840. Date of Electronic Publication: 2021 Apr 15.
Typ publikacji :
Journal Article
MeSH Terms :
Intestinal Absorption*
Models, Biological*
Animals ; Bridged Bicyclo Compounds, Heterocyclic ; Computer Simulation ; Fasting ; Solubility ; Sulfonamides ; Swine
Czasopismo naukowe
Tytuł :
Impact of gastrointestinal tract variability on oral drug absorption and pharmacokinetics: An UNGAP review.
Autorzy :
Vinarov Z; Drug Delivery and Disposition, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium; Department of Chemical and Pharmaceutical Engineering, Sofia University, Sofia, Bulgaria.
Abdallah M; Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Australia.
Agundez JAG; University Institute of Molecular Pathology Biomarkers, UEx. ARADyAL, Instituto de Salud Carlos III, Cáceres, Spain.
Allegaert K; Department of Hospital Pharmacy, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands; Department of Development and Regeneration and Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium.
Basit AW; UCL School of Pharmacy, University College London, London, United Kingdom.
Braeckmans M; Drug Delivery and Disposition, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium.
Ceulemans J; Pharmaceutical Sciences, Janssen Research & Development, Beerse, Belgium.
Corsetti M; NIHR Nottingham Biomedical Research Centre (BRC), Nottingham University Hospitals NHS Trust and the University of Nottingham, Nottingham, United Kingdom; Nottingham Digestive Diseases Centre, School of Medicine, University of Nottingham, Nottingham, United Kingdom.
Griffin BT; School of Pharmacy, University College Cork, Cavanagh Pharmacy Building, Cork, Ireland.
Grimm M; Department of Biopharmaceutics and Pharmaceutical Technology, Center of Drug Absorption and Transport, University of Greifswald, Greifswald, Germany.
Keszthelyi D; Division of Gastroenterology-Hepatology, Department of Internal Medicine, NUTRIM, Maastricht University Medical Center, Maastricht, the Netherlands.
Koziolek M; NCE Formulation Sciences, AbbVie Deutschland GmbH & Co. KG, Ludwigshafen, Germany.
Madla CM; UCL School of Pharmacy, University College London, London, United Kingdom.
Matthys C; Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium; Department of Endocrinology, University Hospitals Leuven, Leuven, Belgium.
McCoubrey LE; UCL School of Pharmacy, University College London, London, United Kingdom.
Mitra A; Clinical Pharmacology and Pharmacometrics, Janssen Research & Development, Spring House, Pennsylvania, United States.
Reppas C; Department of Pharmacy, School of Health Sciences, National and Kapodistrian University of Athens, Athens, Greece.
Stappaerts J; Pharmaceutical Sciences, Janssen Research & Development, Beerse, Belgium.
Steenackers N; Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium.
Trevaskis NL; Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Australia.
Vanuytsel T; Translational Research Centre for Gastrointestinal Disorders (TARGID), Department of Chronic Diseases, Metabolism and Ageing (ChroMeTa), KU Leuven, Leuven, Belgium.
Vertzoni M; Department of Pharmacy, School of Health Sciences, National and Kapodistrian University of Athens, Athens, Greece.
Weitschies W; Department of Biopharmaceutics and Pharmaceutical Technology, Center of Drug Absorption and Transport, University of Greifswald, Greifswald, Germany.
Wilson C; Strathclyde Institute of Pharmacy and Biomedical Sciences (SIPBS), University of Strathclyde, United Kingdom.
Augustijns P; Drug Delivery and Disposition, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium; Chairperson of the UNGAP network, COST CA 16205. Electronic address: .
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Źródło :
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences [Eur J Pharm Sci] 2021 Jul 01; Vol. 162, pp. 105812. Date of Electronic Publication: 2021 Mar 20.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Intestinal Absorption*
Pharmaceutical Preparations*/metabolism
Administration, Oral ; Aged ; Child ; Female ; Food-Drug Interactions ; Gastrointestinal Tract/metabolism ; Humans ; Male ; Pharmacokinetics
Czasopismo naukowe
Tytuł :
The effect of hypergravity in intestinal permeability of nanoformulations and molecules.
Autorzy :
Azevedo C; INEB - Instituto Nacional de Engenharia Biomédica, Universidade do Porto, Rua Alfredo Allen, 208, 4200-135 Porto, Portugal; i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Rua Alfredo Allen, 208, 4200-135 Porto, Portugal; Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto, Rua Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal.
Macedo MH; INEB - Instituto Nacional de Engenharia Biomédica, Universidade do Porto, Rua Alfredo Allen, 208, 4200-135 Porto, Portugal; i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Rua Alfredo Allen, 208, 4200-135 Porto, Portugal; Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto, Rua Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal.
Almeida A; INEB - Instituto Nacional de Engenharia Biomédica, Universidade do Porto, Rua Alfredo Allen, 208, 4200-135 Porto, Portugal; i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Rua Alfredo Allen, 208, 4200-135 Porto, Portugal; Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto, Rua Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal.
Pinto S; INEB - Instituto Nacional de Engenharia Biomédica, Universidade do Porto, Rua Alfredo Allen, 208, 4200-135 Porto, Portugal; i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Rua Alfredo Allen, 208, 4200-135 Porto, Portugal; Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto, Rua Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal.
van Loon JJWA; Department of Oral and Maxillofacial Surgery/Oral Pathology, Amsterdam Movement Sciences & Amsterdam Bone Center (ABC), Amsterdam University Medical Center Location VUmc, De Boelelaan 1117, 1118, 1081 Amsterdam, the Netherlands; European Space Agency (ESA), Technology Center (ESTEC), TEC-MMG LIS Lab, Keplerlaan 1, 2201 AZ Noordwijk, the Netherlands.
Sarmento B; INEB - Instituto Nacional de Engenharia Biomédica, Universidade do Porto, Rua Alfredo Allen, 208, 4200-135 Porto, Portugal; i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Rua Alfredo Allen, 208, 4200-135 Porto, Portugal; CESPU, Instituto de Investigação e Formação Avançada em Ciências e Tecnologias da Saúde, Rua Central da Gandra, 137, 4585-116 Gandra, Portugal. Electronic address: .
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Źródło :
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V [Eur J Pharm Biopharm] 2021 Jun; Vol. 163, pp. 38-48. Date of Electronic Publication: 2021 Mar 27.
Typ publikacji :
Journal Article
MeSH Terms :
Hypergravity*
Intestinal Absorption*
Intestinal Mucosa/*metabolism
Administration, Oral ; Caco-2 Cells ; Camptothecin/administration & dosage ; Camptothecin/chemistry ; Camptothecin/pharmacokinetics ; Dextrans/administration & dosage ; Dextrans/chemistry ; Dextrans/pharmacokinetics ; Drug Carriers/chemistry ; Electric Impedance ; Fluorescein-5-isothiocyanate/administration & dosage ; Fluorescein-5-isothiocyanate/analogs & derivatives ; Fluorescein-5-isothiocyanate/chemistry ; Fluorescein-5-isothiocyanate/pharmacokinetics ; Humans ; Insulin/administration & dosage ; Insulin/chemistry ; Insulin/pharmacokinetics ; Micelles ; Molecular Weight ; Nanoparticles/chemistry ; Permeability ; Tight Junctions/metabolism
Czasopismo naukowe
Tytuł :
Nanoemulsion for Improving the Oral Bioavailability of Hesperetin: Formulation Optimization and Absorption Mechanism.
Autorzy :
Zeng F; School of Pharmaceutical Sciences, Chongqing University, Chongqing, 401331, China.
Wang D; School of Pharmaceutical Sciences, Chongqing University, Chongqing, 401331, China.
Tian Y; School of Pharmaceutical Sciences, Chongqing University, Chongqing, 401331, China.
Wang M; School of Pharmaceutical Sciences, Chongqing University, Chongqing, 401331, China.
Liu R; School of Pharmaceutical Sciences, Chongqing University, Chongqing, 401331, China.
Xia Z; School of Pharmaceutical Sciences, Chongqing University, Chongqing, 401331, China. Electronic address: .
Huang Y; College of Pharmacy, Chongqing Medical University, Chongqing, 400016, China. Electronic address: .
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Źródło :
Journal of pharmaceutical sciences [J Pharm Sci] 2021 Jun; Vol. 110 (6), pp. 2555-2561. Date of Electronic Publication: 2021 Feb 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Intestinal Absorption*
Administration, Oral ; Animals ; Biological Availability ; Emulsions ; Hesperidin ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
Enhancing Intestinal Absorption of a Model Macromolecule via the Paracellular Pathway using E-Cadherin Peptides.
Autorzy :
Dening TJ; Department of Pharmaceutical Chemistry, School of Pharmacy, The University of Kansas, Lawrence, KS 66047, USA.
Siahaan TJ; Department of Pharmaceutical Chemistry, School of Pharmacy, The University of Kansas, Lawrence, KS 66047, USA.
Hageman MJ; Department of Pharmaceutical Chemistry, School of Pharmacy, The University of Kansas, Lawrence, KS 66047, USA. Electronic address: .
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Źródło :
Journal of pharmaceutical sciences [J Pharm Sci] 2021 May; Vol. 110 (5), pp. 2139-2148. Date of Electronic Publication: 2020 Dec 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Intestinal Absorption*
Intestinal Mucosa*/metabolism
Caco-2 Cells ; Cadherins/metabolism ; Humans ; Peptides/metabolism ; Permeability
Czasopismo naukowe
Tytuł :
Nanocrystals for Improving Oral Bioavailability of Drugs: Intestinal Transport Mechanisms and Influencing Factors.
Autorzy :
Tian Z; Department of Pharmaceutics, School of Pharmacy, Ningxia Medical University, Yinchuan, China.
Mai Y; Department of Medical Science and Technology Research Center, Ningxia Medical University, Yinchuan, China.
Meng T; Department of Pharmaceutics, School of Pharmacy, Ningxia Medical University, Yinchuan, China.
Ma S; Department of Pharmaceutics, School of Pharmacy, Ningxia Medical University, Yinchuan, China.
Gou G; Department of Medical Chemistry, School of Basic Medicine, Ningxia Medical University, Yinchuan, China. .
Yang J; Department of Pharmaceutics, School of Pharmacy, Ningxia Medical University, Yinchuan, China. .
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Źródło :
AAPS PharmSciTech [AAPS PharmSciTech] 2021 Jun 14; Vol. 22 (5), pp. 179. Date of Electronic Publication: 2021 Jun 14.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Drug Delivery Systems/*methods
Intestinal Absorption/*drug effects
Nanoparticles/*administration & dosage
Pharmaceutical Preparations/*administration & dosage
Administration, Oral ; Animals ; Biological Availability ; Humans ; Intestinal Absorption/physiology ; Nanoparticles/chemistry ; Nanoparticles/metabolism ; Pharmaceutical Preparations/chemistry ; Pharmaceutical Preparations/metabolism ; Solubility
Czasopismo naukowe
Tytuł :
An imaging approach for determining the mechanism of enhancement of intestinal absorption of an L-theanine supplement.
Autorzy :
Sato Y; Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Hokkaido, Japan.
Yamaguchi K; Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Hokkaido, Japan.
Ogawa M; Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Hokkaido, Japan.; Global Station for Biosurfaces and Drug Discovery, Global Institution for Collaborative Research and Education (GI-CoRE), Hokkaido University, Sapporo, Hokkaido, Japan.
Takekuma Y; Department of Pharmacy, Hokkaido University Hospital, Sapporo, Hokkaido, Japan.
Sugawara M; Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Hokkaido, Japan.; Global Station for Biosurfaces and Drug Discovery, Global Institution for Collaborative Research and Education (GI-CoRE), Hokkaido University, Sapporo, Hokkaido, Japan.; Department of Pharmacy, Hokkaido University Hospital, Sapporo, Hokkaido, Japan.
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Źródło :
PloS one [PLoS One] 2021 Jun 11; Vol. 16 (6), pp. e0253066. Date of Electronic Publication: 2021 Jun 11 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Dietary Supplements*
Intestinal Absorption*
Glutamates/*pharmacokinetics
Animals ; Caco-2 Cells ; Chromatography, High Pressure Liquid ; Glutamates/blood ; Humans ; Male ; Rats ; Rats, Wistar ; Regional Blood Flow
Czasopismo naukowe
Tytuł :
Permeability-enhancing effects of three laurate-disaccharide monoesters across isolated rat intestinal mucosae.
Autorzy :
McCartney F; UCD School of Veterinary Medicine and UCD Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland.
Perinelli DR; School of Pharmacy, University of Camerino, Via Gentile III da Varano, 62032 Camerino, MC, Italy.
Tiboni M; Department of Biomolecular Sciences, University of Urbino Carlo Bo, Piazza del Rinascimento, 6, 61029 Urbino, PU, Italy.
Cavanagh R; Division of Molecular Therapeutics and Formulation, School of Pharmacy, University of Nottingham, Nottingham NG7 2RD, United Kingdom.
Lucarini S; Department of Biomolecular Sciences, University of Urbino Carlo Bo, Piazza del Rinascimento, 6, 61029 Urbino, PU, Italy.
Filippo Palmieri G; School of Pharmacy, University of Camerino, Via Gentile III da Varano, 62032 Camerino, MC, Italy.
Casettari L; Department of Biomolecular Sciences, University of Urbino Carlo Bo, Piazza del Rinascimento, 6, 61029 Urbino, PU, Italy. Electronic address: .
Brayden DJ; UCD School of Veterinary Medicine and UCD Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland. Electronic address: .
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Źródło :
International journal of pharmaceutics [Int J Pharm] 2021 May 15; Vol. 601, pp. 120593. Date of Electronic Publication: 2021 Apr 20.
Typ publikacji :
Journal Article
MeSH Terms :
Intestinal Absorption*
Laurates*
Animals ; Caco-2 Cells ; Disaccharides ; Humans ; Intestinal Mucosa/metabolism ; Permeability ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Effect of dietary macronutrients on intestinal cholesterol absorption and endogenous cholesterol synthesis: a randomized crossover trial.
Autorzy :
Schroor MM; Department of Nutrition and Movement Sciences, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University, 6200 MD, Maastricht, the Netherlands. Electronic address: .
Plat J; Department of Nutrition and Movement Sciences, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University, 6200 MD, Maastricht, the Netherlands.
Konings MCJM; Department of Nutrition and Movement Sciences, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University, 6200 MD, Maastricht, the Netherlands.
Smeets ETHC; Department of Nutrition and Movement Sciences, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University, 6200 MD, Maastricht, the Netherlands.
Mensink RP; Department of Nutrition and Movement Sciences, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University, 6200 MD, Maastricht, the Netherlands.
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Źródło :
Nutrition, metabolism, and cardiovascular diseases : NMCD [Nutr Metab Cardiovasc Dis] 2021 May 06; Vol. 31 (5), pp. 1579-1585. Date of Electronic Publication: 2021 Jan 29.
Typ publikacji :
Comparative Study; Journal Article; Randomized Controlled Trial
MeSH Terms :
Diet, High-Fat*
Diet, High-Protein*
Intestinal Absorption*
Cholesterol/*metabolism
Dietary Carbohydrates/*administration & dosage
Aged ; Biomarkers/blood ; Cholesterol/biosynthesis ; Cholesterol/blood ; Cross-Over Studies ; Dietary Carbohydrates/metabolism ; Double-Blind Method ; Energy Intake ; Humans ; Male ; Middle Aged ; Netherlands ; Postprandial Period ; Time Factors
Czasopismo naukowe

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