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Tytuł :
Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability.
Autorzy :
Lagou V; Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.; Department of Microbiology and Immunology, Laboratory of Adaptive Immunity, KU Leuven, Leuven, Belgium.; VIB-KU Leuven Center for Brain and Disease Research, Leuven, Belgium.
Mägi R; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.
Hottenga JJ; Department of Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands.; Amsterdam Public Health Research Institute, VU University medical center, Amsterdam, the Netherlands.
Grallert H; Research Unit of Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research (DZD, München-Neuherberg, Germany.
Perry JRB; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom.
Bouatia-Naji N; University of Lille Nord de France, Lille, France.; CNRS UMR8199, Institut Pasteur de Lille, Lille, France.; INSERM U970, Paris Cardiovascular Research Center PARCC, 75006, Paris, France.
Marullo L; Department of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Italy.
Rybin D; Boston University Data Coordinating Center, Boston, MA, USA.
Jansen R; Department of Psychiatry, VU University Medical Center, Amsterdam, the Netherlands.
Min JL; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Bristol Medical School, University of Bristol, Bristol, United Kingdom.
Dimas AS; Institute for Bioinnovation, Biomedical Sciences Research Center Al. Fleming, Vari, Greece.
Ulrich A; Department of Medicine, Imperial College London, London, UK.
Zudina L; Department of Medicine, Imperial College London, London, UK.
Gådin JR; Cardiovascular Medicine Unit, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Karolinska University Hospital, Solna, Sweden.
Jiang L; Department of Medicine, Imperial College London, London, UK.; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, 4072, Australia.
Faggian A; Department of Medicine, Imperial College London, London, UK.
Bonnefond A; University of Lille Nord de France, Lille, France.; CNRS UMR8199, Institut Pasteur de Lille, Lille, France.; Department of Medicine, Imperial College London, London, UK.
Fadista J; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.
Stathopoulou MG; Université de Lorraine, IGE-PCV, F-54000, Nancy, France.
Isaacs A; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.; CARIM School for Cardiovascular Diseases and Maastricht Centre for Systems Biology (MaCSBio, Maastricht University, Maastricht, the Netherlands.; Department of Physiology, Maastricht University, Maastricht, the Netherlands.
Willems SM; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.
Navarro P; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, UK.
Tanaka T; Translational Gerontology Branch, Longitudinal Study Section, National Institute on Aging, Baltimore, MD, USA.
Jackson AU; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.
Montasser ME; Division of Endocrinology, Diabetes, and Nutrition, Department of Medicine, University of Maryland, School of Medicine, Baltimore, MD, USA.
O'Connell JR; Division of Endocrinology, Diabetes, and Nutrition, Department of Medicine, University of Maryland, School of Medicine, Baltimore, MD, USA.
Bielak LF; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.
Webster RJ; Laboratory for Cancer Medicine, Harry Perkins Institute of Medical Research, University of Western Australia Centre for Medical Research, Nedlands, WA, Australia.
Saxena R; Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, MA, USA.; Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA, USA.; Department of Genetics, Harvard Medical School, Boston, MA, USA.; Departmentartment of Anesthesia, Critical Care and Pain Medicine, MGH, Boston, MA, USA.
Stafford JM; Department of Biostatistics and Data Science, Division of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Pourcain BS; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Bristol Medical School, University of Bristol, Bristol, United Kingdom.
Timpson NJ; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Bristol Medical School, University of Bristol, Bristol, United Kingdom.
Salo P; Public Health Genomics Unit, Department of Chronic Disease Prevention, Finnish Institute for Health and Welfare, Helsinki, Finland.
Shin SY; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK.
Amin N; Department of Epidemiology Erasmus MC, Rotterdam, the Netherlands.
Smith AV; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.; Icelandic Heart Association, Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.
Li G; Cardiovascular Health Research Unit, University of Washington, Seattle, WA, USA.; Department of Medicine, University of Washington, Seattle, WA, USA.
Verweij N; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Goel A; Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.; Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
Ford I; Robertson Centre for Biostatistics, University of Glasgow, Glasgow, UK.
Johnson PCD; Robertson Centre for Biostatistics, University of Glasgow, Glasgow, UK.; Institute of Biodiversity, Animal Health & Comparative Medicine, University of Glasgow, Glasgow, UK.
Johnson T; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; NIHR Barts Cardiovascular Biomedical Research Unit, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Kapur K; Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland.
Thorleifsson G; deCODE Genetics, Reykjavik, Iceland.
Strawbridge RJ; Cardiovascular Medicine Unit, Department of Medicine, Solna, Karolinska Institutet, Stockholm, Sweden.; Center for Molecular Medicine, Karolinska University Hospital Solna, Stockholm, Sweden.; Institute of Health and Wellbeing, University of Glasgow, Glasgow, UK.
Rasmussen-Torvik LJ; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Esko T; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.
Mihailov E; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.
Fall T; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
Fraser RM; Usher Institute, University of Edinburgh, Edinburgh, UK.; Synpromics Ltd, Roslin Innovation Centre, Easter Bush Campus, Edinburgh, EH25 9RG, UK.
Mahajan A; Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.; Genentech, 340 Point San Bruno Boulevard, South San Francisco, CA, 94080, USA.
Kanoni S; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Wellcome Trust Sanger Institute, Hinxton, UK.
Giedraitis V; Department of Public Health and Caring Sciences, Uppsala Universitet, Uppsala, Sweden.
Kleber ME; Vth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Silbernagel G; Division of Angiology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.
Meyer J; Institute of Genetic Epidemiology,Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.
Müller-Nurasyid M; Institute of Genetic Epidemiology,Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Medical Informatics, Biometry and Epidemiology, Chair of Epidemiology and Chair of Genetic Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany.; Department of Medicine I, University Hospital Grosshadern, Ludwig-Maximilians-University, Munich, Germany.; Institute of Medical Biostatistics, Epidemiology and Informatics (IMBEI, University Medical Center, Johannes Gutenberg University, 55101, Mainz, Germany.
Ganna A; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Sarin AP; Institute for Molecular Medicine Finland, FIMM, University of Helsinki, Helsinki, Finland.; Public Health Genomics Unit, Finnish Institute for Health and Welfare, Helsinki, Finland.
Yengo L; University of Lille Nord de France, Lille, France.; CNRS UMR8199, Institut Pasteur de Lille, Lille, France.; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, 4072, Australia.
Shungin D; Department of Public Health & Clinical Medicine, Umeå University, Umeå, Sweden.; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Skåne University Hospital Malmö, Malmö, Sweden.; Department of Odontology, Umeå University, Umeå, Sweden.
Luan J; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom.
Horikoshi M; Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK.; RIKEN, Center for Integrative Medical Sciences, Laboratory for Endocrinology, Metabolism and Kidney Disease, Yokohama, Japan.
An P; Division of Statistical Genomics, Washington University School of Medicine, St. Louis, MO, USA.
Sanna S; Istituto di Ricerca Genetica e Biomedica, CNR, Monserrato, Italy.; Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
Boettcher Y; Department of Medicine, University of Leipzig, Leipzig, Germany.; IFB AdiposityDiseases, University of Leipzig, Leipzig, Germany.
Rayner NW; Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.; Wellcome Trust Sanger Institute, Hinxton, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK.
Nolte IM; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Zemunik T; Faculty of Medicine, University of Split, Split, Croatia.
Iperen EV; Department of Clinical Epidemiology and Biostatistics, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands.
Kovacs P; IFB AdiposityDiseases, University of Leipzig, Leipzig, Germany.
Hastie ND; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, UK.
Wild SH; Usher Institute, University of Edinburgh, Edinburgh, UK.
McLachlan S; Usher Institute, University of Edinburgh, Edinburgh, UK.
Campbell S; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, UK.
Polasek O; Faculty of Medicine, University of Split, Split, Croatia.
Carlson O; Laboratory of Clinical Investigation, National Institute of Aging, Baltimore, MD, USA.
Egan J; Laboratory of Clinical Investigation, National Institute of Aging, Baltimore, MD, USA.
Kiess W; IFB AdiposityDiseases, University of Leipzig, Leipzig, Germany.; Pediatric Research Center, Department of Women's & Child Health, University of Leipzig, Leipzig, Germany.
Willemsen G; Department of Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands.
Kuusisto J; Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland.
Laakso M; Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland.
Dimitriou M; Department of Dietetics-Nutrition, Harokopio University, Athens, Greece.
Hicks AA; Center for Biomedicine, European Academy Bozen/Bolzano (EURAC) (Affiliated Institute of the University of LübeckLübeckGermany), Bolzano, Italy.
Rauramaa R; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland.
Bandinelli S; Geriatric Unit, Azienda Sanitaria Firenze (ASF), Florence, Italy.
Thorand B; German Center for Diabetes Research (DZD, München-Neuherberg, Germany.; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.
Liu Y; Department of Epidemiology and Prevention, Division of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Miljkovic I; Department of Epidemiology, Center for Aging and Population Health, University of Pittsburgh, Pittsburgh, PA, USA.
Lind L; Department of Medical Sciences, Uppsala University, Akademiska sjukhuset, Uppsala, Sweden.
Doney A; Pat McPherson Centre for Pharmacogenetics and Pharmacogenomics, Division of Molecular and Clinical Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK.
Perola M; Public Health Genomics Unit, Department of Chronic Disease Prevention, Finnish Institute for Health and Welfare, Helsinki, Finland.; Institute for Molecular Medicine Finland, FIMM, University of Helsinki, Helsinki, Finland.; Estonian Genome Center, University of Tartu, Tartu, Estonia.
Hingorani A; Department of Epidemiology and Public Health, University College London, London, UK.
Kivimaki M; Department of Epidemiology and Public Health, University College London, London, UK.
Kumari M; Department of Epidemiology and Public Health, University College London, London, UK.; University of Essex, Wivenhoe Park, Colchester, Essex, UK.
Bennett AJ; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK.
Groves CJ; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK.
Herder C; German Center for Diabetes Research (DZD, München-Neuherberg, Germany.; Institute of Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University Düsseldorf, Düsseldorf, Germany.; Division of Endocrinology and Diabetology, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
Koistinen HA; Department of Public Health Solutions, Finnish Institute for Health and Welfare, P.O. Box 30, Helsinki, FI-00271, Finland.; Department of Medicine, University of Helsinki and Helsinki University Central Hospital, P.O. Box 340, Haartmaninkatu 4, Helsinki, FI-00029, Finland.; Minerva Foundation Institute for Medical Research, Biomedicum 2U, Tukholmankatu 8, Helsinki, FI-00290, Finland.
Kinnunen L; Department of Public Health Solutions, Finnish Institute for Health and Welfare, P.O. Box 30, Helsinki, FI-00271, Finland.
Faire U; Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Bakker SJL; Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Uusitupa M; Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland.
Palmer CNA; Pat McPherson Centre for Pharmacogenetics and Pharmacogenomics, Division of Molecular and Clinical Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK.
Jukema JW; Dept of Cardiology, Leiden University Medical Center, Leiden, the Netherlands.; Netherlands Heart Institute, Utrecht, the Netherlands.
Sattar N; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, United Kingdom.
Pouta A; Department of Government Services, Finnish Institute for Health and Welfare, Helsinki, Finland.; PEDEGO Research Unit, Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland.
Snieder H; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Boerwinkle E; IMM Center for Human Genetics, University of Texas Health Science Center at Houston, Houston, TX, USA.; Division of Epidemiology, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA.
Pankow JS; Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MiI, USA.
Magnusson PK; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Krus U; Department of Clinical Sciences, Diabetes and Endocrinology Research Unit, University Hospital Malmö, Lund University, Malmö, Sweden.
Scapoli C; Department of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Italy.
de Geus EJCN; Department of Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands.; Amsterdam Public Health Research Institute, VU University medical center, Amsterdam, the Netherlands.
Blüher M; Department of Medicine, University of Leipzig, Leipzig, Germany.; Department of Preventive Medicine, Keck School of Medicine of USC, Los Angeles, CA, USA.
Wolffenbuttel BHR; Department of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Province MA; Division of Statistical Genomics, Washington University School of Medicine, St. Louis, MO, USA.
Abecasis GR; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.
Meigs JB; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; General Medicine Division, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.
Hovingh GK; Department of Vascular Medicine, Amsterdam UMC, Amsterdam, the Netherlands.; Novo Nordisk A/S, Copenhagen, Denmark.
Lindström J; Finnish Institute for Health and Welfare, Diabetes Prevention Unit, Helsinki, Finland.
Wilson JF; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, UK.; Usher Institute, University of Edinburgh, Edinburgh, UK.
Wright AF; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, UK.
Dedoussis GV; Department of Dietetics-Nutrition, Harokopio University, Athens, Greece.
Bornstein SR; Department of Medicine, Division for Prevention and Care of Diabetes, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Schwarz PEH; Department for Prevention and Care of Diabetes, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.; Paul Langerhans Institute Dresden of the Helmholtz Center Munich at University Hospital and Faculty of Medicine, TU Dresden, Dresden, Germany.; German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany.
Tönjes A; Department of Medicine, University of Leipzig, Leipzig, Germany.; IFB AdiposityDiseases, University of Leipzig, Leipzig, Germany.
Winkelmann BR; Cardiology Group, Frankfurt-Sachsenhausen, Germany.
Boehm BO; Lee Kong Chian School of Medicine, Nanyang Technological University Singapore and Imperial College London, Singapore, Singapore.
März W; Vth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; Synlab Academy, Synlab Holding Deutschland GmbH, Mannheim, Germany.
Metspalu A; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.
Price JF; Usher Institute, University of Edinburgh, Edinburgh, UK.
Deloukas P; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Wellcome Trust Sanger Institute, Hinxton, UK.; Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD, King Abdulaziz University, Jeddah, Saudi Arabia.
Körner A; IFB AdiposityDiseases, University of Leipzig, Leipzig, Germany.; Diabetes Research Center, Diabetes Unit, Massachusetts General Hospital, Boston, MA, USA.
Lakka TA; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Institute of Biomedicine/Physiology, University of Eastern Finland, Kuopio Campus, Kuopio, Finland.
Keinanen-Kiukaanniemi SM; Faculty of Medicine, Center for Life Course Health Research, University of Oulu, Oulu, Finland.; Unit of General Practice, Oulu University Hospital, Oulu, Finland.
Saaristo TE; Finnish Diabetes Association, Tampere, Finland.; Pirkanmaa Hospital District, Tampere, Finland.
Bergman RN; Diabetes and Obesity Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Tuomilehto J; Department of Chronic Disease Prevention, Finnish Institute for Health and Welfare, Helsinki, Finland.; Department of Public Health, University of Helsinki, Helsinki, Finland.; Centre for Vascular Prevention, Danube-University Krems, Krems, Austria.; Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia.
Wareham NJ; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom.
Langenberg C; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom.
Männistö S; Department of Public Health Solutions, Finnish Institute for Health and Welfare, P.O. Box 30, Helsinki, FI-00271, Finland.
Franks PW; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Skåne University Hospital Malmö, Malmö, Sweden.; Department of Nutrition, Harvard School of Public Health, Boston, MA, USA.; Department of Public Health & Clinical Medicine, Units of Medicine and Nutritional Research, Umeå University, Umeå, Sweden.
Hayward C; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, UK.
Vitart V; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, UK.
Kaprio J; Institute for Molecular Medicine Finland, FIMM, University of Helsinki, Helsinki, Finland.; Department of Public Health, University of Helsinki, Helsinki, Finland.
Visvikis-Siest S; Université de Lorraine, IGE-PCV, F-54000, Nancy, France.
Balkau B; Inserm, CESP Center for Research in Epidemiology and Public Health, U1018, Villejuif, France.; Univ Paris-Saclay, Univ Paris Sud, UVSQ, UMRS 1018, UMRS 1018, Villejuif, France.
Altshuler D; Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, MA, USA.; Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.
Rudan I; Usher Institute, University of Edinburgh, Edinburgh, UK.
Stumvoll M; Department of Medicine, University of Leipzig, Leipzig, Germany.; IFB AdiposityDiseases, University of Leipzig, Leipzig, Germany.
Campbell H; Usher Institute, University of Edinburgh, Edinburgh, UK.
van Duijn CM; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.; Centre for Medical Systems Biology, Leiden, the Netherlands.
Gieger C; Research Unit of Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research (DZD, München-Neuherberg, Germany.; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.
Illig T; Research Unit of Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München Research Center for Environmental Health, Neuherberg, Germany.; Hannover Unified Biobank, Hannover Medical School, Hannover, Germany.; Institute of Human Genetics, Hannover Medical School, Hannover, Germany.
Ferrucci L; Clinical Research Branch, National Institute on Aging, Baltimore, Maryland, USA.
Pedersen NL; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Pramstaller PP; Center for Biomedicine, European Academy Bozen/Bolzano (EURAC) (Affiliated Institute of the University of LübeckLübeckGermany), Bolzano, Italy.; Department of Neurology, General Central Hospital, Bolzano, Italy.; Department of Neurology, University of Lübeck, Lübeck, Germany.
Boehnke M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.
Frayling TM; Genetics of Complex Traits, Peninsula Medical School, University of Exeter, Exeter, UK.
Shuldiner AR; Division of Endocrinology, Diabetes, and Nutrition, Department of Medicine, University of Maryland, School of Medicine, Baltimore, MD, USA.; The Regeneron Genetics Center, Regeneron Pharmaceuticals, Tarrytown, NY, USA.
Peyser PA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.
Kardia SLR; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.
Palmer LJ; School of Public Health, University of Adelaide, Adelaide, Australia.
Penninx BW; Department of Psychiatry, VU University Medical Center, Amsterdam, the Netherlands.
Meneton P; U872 Institut National de la Santé et de la Recherche Médicale, Centre de Recherche des Cordeliers, 75006, Paris, France.
Harris TB; Geriatric Epidemiology Section, Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Bethesda, MD, USA.
Navis G; Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Harst PV; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.; Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
Smith GD; MRC Integrative Epidemiology Unit (IEU), University of Bristol, Bristol, UK.
Forouhi NG; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom.
Loos RJF; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom.; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Salomaa V; Finnish Institute for Health and Welfare, Helsinki, Finland.
Soranzo N; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK.
Boomsma DI; Department of Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands.
Groop L; Institute for Molecular Medicine Finland, FIMM, University of Helsinki, Helsinki, Finland.; Department of Clinical Sciences, Diabetes and Endocrinology Research Unit, University Hospital Malmö, Lund University, Malmö, Sweden.
Tuomi T; Institute for Molecular Medicine Finland, FIMM, University of Helsinki, Helsinki, Finland.; Department of Clinical Sciences, Diabetes and Endocrinology Research Unit, University Hospital Malmö, Lund University, Malmö, Sweden.; Endocrinology, Abdominal Centre, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.; Research Program for Clinical and Molecular Metabolism, University of Helsinki and Folkhälsan Research Center, Helsinki, Finland.
Hofman A; Department of Epidemiology Erasmus MC, Rotterdam, the Netherlands.; Netherlands Consortium for healthy ageing, the Hague, the Netherlands.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, USA.
Munroe PB; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; NIHR Barts Cardiovascular Biomedical Research Unit, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Gudnason V; Icelandic Heart Association, Kopavogur, Iceland.; Faculty of Medicine University of Iceland, Reykjavik, Iceland.
Siscovick DS; Cardiovascular Health Research Unit, University of Washington, Seattle, WA, USA.; Department of Medicine, University of Washington, Seattle, WA, USA.; Department of Epidemiology, University of Washington, Seattle, WA, USA.
Watkins H; Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.; Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
Lecoeur C; University of Lille Nord de France, Lille, France.; CNRS UMR8199, Institut Pasteur de Lille, Lille, France.
Vollenweider P; Department of Medicine, University Hospital Lausanne, Lausanne, Switzerland.
Franco-Cereceda A; Cardiothoracic Surgery Unit, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
Eriksson P; Cardiovascular Medicine Unit, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Karolinska University Hospital, Solna, Sweden.
Jarvelin MR; Department of Epidemiology and Biostatistics and HPA-MRC Center, School of Public Health, Imperial College London, London, UK.; Institue of Health Sciences, University of Oulu, Oulu, Finland.
Stefansson K; deCODE Genetics, Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavík, Iceland.
Hamsten A; Cardiovascular Medicine Unit, Department of Medicine, Solna, Karolinska Institutet, Stockholm, Sweden.; Center for Molecular Medicine, Karolinska University Hospital Solna, Stockholm, Sweden.; Department of Cardiology, Karolinska University Hospital Solna, Stockholm, Sweden.
Nicholson G; Department of Statistics, University of Oxford, Oxford, UK.
Karpe F; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK.; Oxford National Institute for Health Research Biomedical Research Centre, Churchill Hospital, Oxford, UK.
Dermitzakis ET; Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland.
Lindgren CM; Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.; Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, MA, USA.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK.; Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK.
McCarthy MI; Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK.; Oxford National Institute for Health Research Biomedical Research Centre, Churchill Hospital, Oxford, UK.; Genentech, 340 Point San Bruno Boulevard, South San Francisco, CA, 94080, USA.
Froguel P; University of Lille Nord de France, Lille, France.; CNRS UMR8199, Institut Pasteur de Lille, Lille, France.; Department of Medicine, Imperial College London, London, UK.
Kaakinen MA; Department of Medicine, Imperial College London, London, UK.; School of Biosciences and Medicine, Department of Clinical and Experimental Medicine, University of Surrey, Guildford, UK.
Lyssenko V; Department of Clinical Sciences, Diabetes and Endocrinology Research Unit, University Hospital Malmö, Lund University, Malmö, Sweden.; Department of Clinical Science, University of Bergen, Bergen, Norway.
Watanabe RM; Department of Preventive Medicine, Keck School of Medicine of USC, Los Angeles, CA, USA.; Department of Physiology & Neuroscience, Keck School of Medicine of USC, Los Angeles, CA, USA.; USC Diabetes and Obesity Research Institute, Los Angeles, CA, USA.
Ingelsson E; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.; Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, USA.; Stanford Cardiovascular Institute, Stanford University, Stanford, CA, 94305, USA.
Florez JC; Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA, USA.; Diabetes Research Center, Diabetes Unit, Massachusetts General Hospital, Boston, MA, USA.
Dupuis J; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
Barroso I; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK.; University of Cambridge Metabolic Research Laboratories and NIHR Cambridge Biomedical Research Centre, Wellcome Trust-MRC Institute of Metabolic Science, Cambridge, UK.; Exeter Centre of ExcEllence in Diabetes (ExCEED), University of Exeter Medical School, Exeter, UK.
Morris AP; Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.; Estonian Genome Center, University of Tartu, Tartu, Estonia.; Department of Biostatistics, University of Liverpool, Liverpool, UK.; Centre for Genetics and Genomics Versus Arthritis, Centre for Musculoskeletal Research, The University of Manchester, Manchester, UK.
Prokopenko I; Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom. .; Department of Medicine, Imperial College London, London, UK. .; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK. .; School of Biosciences and Medicine, Department of Clinical and Experimental Medicine, University of Surrey, Guildford, UK. .; Institute of Biochemistry and Genetics, Ufa Federal Research Centre Russian Academy of Sciences, Ufa, Russian Federation. .
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Corporate Authors :
Meta-Analyses of Glucose and Insulin-related traits Consortium (MAGIC)
Źródło :
Nature communications [Nat Commun] 2021 Jan 05; Vol. 12 (1), pp. 24. Date of Electronic Publication: 2021 Jan 05.
Typ publikacji :
Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Anorexia Nervosa/*genetics
Blood Glucose/*metabolism
Glucose Intolerance/*genetics
Insulin/*blood
Insulin Receptor Substrate Proteins/*genetics
Insulin Resistance/*genetics
Kruppel-Like Transcription Factors/*genetics
Adult ; Anorexia Nervosa/blood ; Anorexia Nervosa/ethnology ; Anorexia Nervosa/physiopathology ; European Continental Ancestry Group ; Fasting/blood ; Female ; Gene Expression ; Genetic Loci ; Genome-Wide Association Study ; Glucose Intolerance/blood ; Glucose Intolerance/ethnology ; Glucose Intolerance/physiopathology ; Humans ; Insulin Receptor Substrate Proteins/blood ; Kruppel-Like Transcription Factors/blood ; Male ; Middle Aged ; Phenotype ; Sex Characteristics ; Sex Factors ; Waist-Hip Ratio
Czasopismo naukowe
Tytuł :
Toward targeted prevention: risk factors for prediabetes defined by impaired fasting glucose, impaired glucose tolerance and increased HbA1c in the population-based KORA study from Germany.
Autorzy :
Greiner GG; Institute for Health Services Research and Health Economics, German Diabetes Center, Auf'm Hennekamp 65, 40225, Duesseldorf, Germany. .; Medical Faculty, Centre for Health and Society, Institute for Health Services Research and Health Economics, Heinrich Heine University, Moorenstr. 5, 40225, Duesseldorf, Germany. .; Institute of Health Economics and Health Care Management, Helmholtz Zentrum München GmbH, German Research Center for Environmental Health, Ingolstädter Landstraße 1, 85764, Neuherberg, Germany. .
Emmert-Fees KMF; Institute of Health Economics and Health Care Management, Helmholtz Zentrum München GmbH, German Research Center for Environmental Health, Ingolstädter Landstraße 1, 85764, Neuherberg, Germany.
Becker J; Institute of Health Economics and Health Care Management, Helmholtz Zentrum München GmbH, German Research Center for Environmental Health, Ingolstädter Landstraße 1, 85764, Neuherberg, Germany.; Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, University Hospital Munich, Ludwig-Maximilians-University Munich, Ziemssenstr. 1, 80336, Munich, Germany.
Rathmann W; Institute for Biometry and Epidemiology, German Diabetes Center, Auf'm Hennekamp 65, 40225, Duesseldorf, Germany.; German Centre for Diabetes Research (DZD), Ingolstädter Landstraße 1, 85764, Munich-Neuherberg, Germany.
Thorand B; German Centre for Diabetes Research (DZD), Ingolstädter Landstraße 1, 85764, Munich-Neuherberg, Germany.; Institute of Epidemiology, Helmholtz Zentrum München GmbH, German Research Center for Environmental Health, Ingolstädter Landstraße 1, 85764, Neuherberg, Germany.
Peters A; German Centre for Diabetes Research (DZD), Ingolstädter Landstraße 1, 85764, Munich-Neuherberg, Germany.; Institute of Epidemiology, Helmholtz Zentrum München GmbH, German Research Center for Environmental Health, Ingolstädter Landstraße 1, 85764, Neuherberg, Germany.
Quante AS; Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), Ingolstädter Landstraße 1, 85764, Neuherberg, Germany.; Department of Gynecology and Obstetrics, Klinikum Rechts der Isar der Technischen Universität München, Ismaninger Str. 22, 81675, Munich, Germany.
Schwettmann L; Institute of Health Economics and Health Care Management, Helmholtz Zentrum München GmbH, German Research Center for Environmental Health, Ingolstädter Landstraße 1, 85764, Neuherberg, Germany.; Department of Economics, Martin Luther University Halle-Wittenberg, 06099, Halle (Saale), Germany.
Laxy M; Institute of Health Economics and Health Care Management, Helmholtz Zentrum München GmbH, German Research Center for Environmental Health, Ingolstädter Landstraße 1, 85764, Neuherberg, Germany.; German Centre for Diabetes Research (DZD), Ingolstädter Landstraße 1, 85764, Munich-Neuherberg, Germany.; Global Diabetes Research Center, Rollins School of Public Health, Emory University, 1518 Clifton Rd., NE, Atlanta, GA, 30322, USA.
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Źródło :
Acta diabetologica [Acta Diabetol] 2020 Dec; Vol. 57 (12), pp. 1481-1491. Date of Electronic Publication: 2020 Aug 03.
Typ publikacji :
Journal Article; Observational Study
MeSH Terms :
Diabetes Mellitus, Type 2/*prevention & control
Glucose Intolerance/*diagnosis
Glycated Hemoglobin A/*metabolism
Prediabetic State/*diagnosis
Prediabetic State/*epidemiology
Preventive Medicine/*trends
Adult ; Aged ; Blood Glucose/analysis ; Blood Glucose/metabolism ; Diabetes Mellitus, Type 2/diagnosis ; Diabetes Mellitus, Type 2/epidemiology ; Diabetes Mellitus, Type 2/etiology ; Fasting/blood ; Female ; Germany/epidemiology ; Glucose Intolerance/blood ; Glucose Intolerance/epidemiology ; Glucose Intolerance/etiology ; Glycated Hemoglobin A/analysis ; Health Services Needs and Demand/organization & administration ; Health Services Needs and Demand/trends ; Humans ; Male ; Middle Aged ; Prediabetic State/blood ; Prediabetic State/etiology ; Preventive Medicine/methods ; Risk Factors ; Socioeconomic Factors ; Young Adult
Czasopismo naukowe
Tytuł :
Prediabetic Dysglycemia: Call for Action.
Autorzy :
Sjöholm Å; Department of Internal Medicine, Division of Endocrinology and Diabetology, Gavle Hospital, SE-80324 Gavle, Sweden.
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Źródło :
Current diabetes reviews [Curr Diabetes Rev] 2021; Vol. 17 (1), pp. 21-25.
Typ publikacji :
Journal Article
MeSH Terms :
Diabetes Mellitus, Type 2*/complications
Diabetes Mellitus, Type 2*/epidemiology
Glucose Intolerance*
Prediabetic State*/epidemiology
Prediabetic State*/therapy
Blood Glucose ; Glucose Tolerance Test ; Humans ; Risk Factors
Czasopismo naukowe
Tytuł :
Asymmetrical dimethylarginine induces dysfunction of insulin signal transduction via endoplasmic reticulum stress in the liver of diabetic rats.
Autorzy :
Qiu N; Department of Central Laboratory, The Fifth Affiliated Hospital of Guangzhou Medical University, Guangzhou 510700, Guangdong, PR China; Department of Breast Surgery, Clinical Key Specialty Project of Guangzhou Medical University, Affiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou 510095, Guangdong, PR China; Guangzhou Institute of Snake Venom Research, Guangzhou 511436, Guangdong, PR China.
Wei XM; Guangzhou Institute of Snake Venom Research, Guangzhou 511436, Guangdong, PR China.
Zhang ZJ; Department of Breast Surgery, Clinical Key Specialty Project of Guangzhou Medical University, Affiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou 510095, Guangdong, PR China.
He YL; Guangzhou Institute of Snake Venom Research, Guangzhou 511436, Guangdong, PR China.
Zhou XK; Department of Central Laboratory, The Fifth Affiliated Hospital of Guangzhou Medical University, Guangzhou 510700, Guangdong, PR China. Electronic address: .
Xiong Y; Department of Central Laboratory, The Fifth Affiliated Hospital of Guangzhou Medical University, Guangzhou 510700, Guangdong, PR China; Guangzhou Institute of Snake Venom Research, Guangzhou 511436, Guangdong, PR China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 Nov 01; Vol. 260, pp. 118373. Date of Electronic Publication: 2020 Sep 06.
Typ publikacji :
Journal Article
MeSH Terms :
Insulin Resistance*
Arginine/*analogs & derivatives
Diabetes Mellitus, Experimental/*pathology
Endoplasmic Reticulum Stress/*drug effects
Glucose Intolerance/*pathology
Insulin/*metabolism
Liver/*pathology
Animals ; Apoptosis ; Arginine/toxicity ; Diabetes Mellitus, Experimental/chemically induced ; Glucose Intolerance/chemically induced ; Hepatocytes/drug effects ; Hepatocytes/pathology ; Liver/drug effects ; Male ; Rats ; Rats, Sprague-Dawley ; Signal Transduction
Czasopismo naukowe
Tytuł :
Epigenetic repression of AT2 receptor is involved in β cell dysfunction and glucose intolerance of adult female offspring rats exposed to dexamethasone prenatally.
Autorzy :
Kou H; Department of Pharmacology, School of Basic Medical Sciences, Wuhan University, Wuhan 430071, China; Department of Pharmacy, Zhongnan Hospital of Wuhan University, Wuhan 40071, China; Hubei Provincial Key Laboratory of Developmentally Originated Diseases, Wuhan 430071, China.
Gui S; Department of Pharmacology, School of Basic Medical Sciences, Wuhan University, Wuhan 430071, China.
Dai Y; Department of Pharmacology, School of Basic Medical Sciences, Wuhan University, Wuhan 430071, China.
Guo Y; Department of Pharmacology, School of Basic Medical Sciences, Wuhan University, Wuhan 430071, China; Hubei Provincial Key Laboratory of Developmentally Originated Diseases, Wuhan 430071, China. Electronic address: .
Wang H; Department of Pharmacology, School of Basic Medical Sciences, Wuhan University, Wuhan 430071, China; Hubei Provincial Key Laboratory of Developmentally Originated Diseases, Wuhan 430071, China. Electronic address: .
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Źródło :
Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2020 Oct 01; Vol. 404, pp. 115187. Date of Electronic Publication: 2020 Aug 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Glucose Intolerance*
Prenatal Exposure Delayed Effects*
Dexamethasone/*toxicity
Insulin-Secreting Cells/*metabolism
Receptor, Angiotensin, Type 2/*metabolism
Animals ; Epigenesis, Genetic ; Female ; Gene Expression Regulation/drug effects ; Glucocorticoids/toxicity ; Pregnancy ; Rats ; Receptor, Angiotensin, Type 2/genetics
Czasopismo naukowe
Tytuł :
The Effect of Self-Reported Lactose Intolerance and Dairy Consumption on Bone Mineral Density Among American Hip Arthroplasty Patients: A Cross-Sectional Study.
Autorzy :
Hamilton NK; School of Life Sciences, University of Westminster, London W1W 6UW, UK.
Ojo O; School of Health Sciences, Faculty of Education, Health and Human Sciences, University of Greenwich, London SE9 2UG, UK.
Adegboye ARA; School of Human Sciences, Faculty of Education, Health and Human Sciences, University of Greenwich, London SE10 9LS, UK.
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Źródło :
International journal of environmental research and public health [Int J Environ Res Public Health] 2020 Sep 30; Vol. 17 (19). Date of Electronic Publication: 2020 Sep 30.
Typ publikacji :
Journal Article
MeSH Terms :
Arthroplasty, Replacement, Hip*/adverse effects
Dairy Products*
Lactose Intolerance*/epidemiology
Absorptiometry, Photon ; Animals ; Bone Density ; Cross-Sectional Studies ; Diet ; Female ; Femur Neck ; Humans ; Lumbar Vertebrae ; Male ; Retrospective Studies ; Self Report ; United States
Czasopismo naukowe
Tytuł :
Artificial Intelligence Uncovered Clinical Factors for Cardiovascular Events in Myocardial Infarction Patients with Glucose Intolerance.
Autorzy :
Shindo K; Saha Cardiovascular Research Center, University of Kentucky, Lexington, KY, USA.
Fukuda H; Department of Clinical Research and Development, National Cerebral and Cardiovascular Center, 6-1 Kishibe-Shimmachi, Suita, Osaka, Japan.
Hitsumoto T; Department of Clinical Research and Development, National Cerebral and Cardiovascular Center, 6-1 Kishibe-Shimmachi, Suita, Osaka, Japan.
Miyashita Y; Department of Legal Medicine, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, Japan.
Kim J; Kim Cardiovascular Clinic, 3-6-8 Katsuyama, Tennoji-ku, Osaka, Japan.
Ito S; Department of Clinical Research and Development, National Cerebral and Cardiovascular Center, 6-1 Kishibe-Shimmachi, Suita, Osaka, Japan.
Washio T; The Institute of Scientific and Industrial Research, Osaka University, 1-1 Yamadaoka, Suita, Osaka, Japan.
Kitakaze M; Department of Clinical Research and Development, National Cerebral and Cardiovascular Center, 6-1 Kishibe-Shimmachi, Suita, Osaka, Japan. .; Hanwa Daini Senboku Hospital, 3176 Fukaikitamachi, Naka-ku, Sakai, Osaka, Japan. .
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Źródło :
Cardiovascular drugs and therapy [Cardiovasc Drugs Ther] 2020 Aug; Vol. 34 (4), pp. 535-545.
Typ publikacji :
Journal Article
MeSH Terms :
Artificial Intelligence*
Data Mining*
Angina, Stable/*etiology
Coronary Artery Disease/*etiology
Glucose Intolerance/*complications
Myocardial Infarction/*etiology
Aged ; Angina, Stable/diagnosis ; Angina, Stable/therapy ; Biomarkers/blood ; Blood Glucose/metabolism ; Coronary Artery Disease/diagnosis ; Coronary Artery Disease/therapy ; Databases, Factual ; Female ; Glucose Intolerance/blood ; Glucose Intolerance/diagnosis ; Heart Failure/etiology ; Heart Failure/therapy ; Hospitalization ; Humans ; Male ; Middle Aged ; Myocardial Infarction/diagnosis ; Myocardial Infarction/therapy ; Natriuretic Peptide, Brain/blood ; Percutaneous Coronary Intervention ; Prognosis ; Proton Pump Inhibitors/therapeutic use ; Randomized Controlled Trials as Topic ; Recurrence ; Retrospective Studies ; Risk Factors
Czasopismo naukowe
Tytuł :
Exposure to Low Doses of Dechlorane Plus Promotes Adipose Tissue Dysfunction and Glucose Intolerance in Male Mice.
Autorzy :
Peshdary V; Environmental Health Science and Research Bureau, Health Canada, 50 Colombine Driveway, Ottawa, Canada.; Departments of Medicine and of Biochemistry, Microbiology, and Immunology, University of Ottawa, Ottawa, Canada.
Styles G; Environmental Health Science and Research Bureau, Health Canada, 50 Colombine Driveway, Ottawa, Canada.
Rigden M; Environmental Health Science and Research Bureau, Health Canada, 50 Colombine Driveway, Ottawa, Canada.
Caldwell D; Scientific Services Division, Health Products and Foods Branch, Health Canada, Ottawa, Ontario, Canada.
Kawata A; Environmental Health Science and Research Bureau, Health Canada, 50 Colombine Driveway, Ottawa, Canada.
Sorisky A; Departments of Medicine and of Biochemistry, Microbiology, and Immunology, University of Ottawa, Ottawa, Canada.; Chronic Disease Program, Ottawa Hospital Research Institute, Ottawa, Canada.
Atlas E; Environmental Health Science and Research Bureau, Health Canada, 50 Colombine Driveway, Ottawa, Canada.; Departments of Medicine and of Biochemistry, Microbiology, and Immunology, University of Ottawa, Ottawa, Canada.
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Źródło :
Endocrinology [Endocrinology] 2020 Aug 01; Vol. 161 (8).
Typ publikacji :
Journal Article
MeSH Terms :
Adipose Tissue, White/*drug effects
Endocrine Disruptors/*pharmacology
Glucose Intolerance/*chemically induced
Hydrocarbons, Chlorinated/*pharmacology
Lipid Metabolism Disorders/*chemically induced
Polycyclic Compounds/*pharmacology
3T3-L1 Cells ; Adipose Tissue, White/metabolism ; Adipose Tissue, White/physiopathology ; Adult ; Aged ; Animals ; Cells, Cultured ; Dose-Response Relationship, Drug ; Female ; Glucose Intolerance/metabolism ; Glucose Intolerance/pathology ; Humans ; Lipid Metabolism/drug effects ; Lipid Metabolism Disorders/metabolism ; Lipid Metabolism Disorders/pathology ; Male ; Mice ; Mice, Inbred C57BL ; Middle Aged ; Pregnancy
Czasopismo naukowe
Tytuł :
Importance of food allergy and food intolerance in allergic multimorbidity.
Autorzy :
Skoczylas D; Faculty of Health Sciences, Medical University, Warsaw, Poland.
Gujski M; Department of Prevention of Environmental Hazards and Allergology, Medical University, Warsaw, Poland.
Bojar I; Department of Women's Health, Institute of Rural Health, Lublin, Poland.
Raciborski F; Department of Prevention of Environmental Hazards and Allergology, Medical University, Warsaw, Poland.
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Źródło :
Annals of agricultural and environmental medicine : AAEM [Ann Agric Environ Med] 2020 Sep 11; Vol. 27 (3), pp. 413-417. Date of Electronic Publication: 2020 Jun 09.
Typ publikacji :
Journal Article
MeSH Terms :
Multimorbidity*
Food Hypersensitivity/*epidemiology
Food Intolerance/*epidemiology
Adolescent ; Child ; Cross-Sectional Studies ; Female ; Food Hypersensitivity/etiology ; Food Intolerance/etiology ; Humans ; Hypersensitivity/epidemiology ; Hypersensitivity/etiology ; Male ; Poland/epidemiology ; Prevalence
Czasopismo naukowe
Tytuł :
KHK inhibition for the treatment of hereditary fructose intolerance and nonalcoholic fatty liver disease: a double-edged sword.
Autorzy :
Pinheiro FC; Graduate Program in Genetics and Molecular Biology, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, Rio Grande do Sul RS, Brazil. .; BRAIN Laboratory, Experimental Research Center, Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, RS, Brazil. .; Federal University of Pampa (Unipampa), Itaqui, RS, Brazil. .; Medical Genetic Service, Hospital de Clínicas de Porto Alegre, Rua Ramiro Barcelos, 350, Porto Alegre, RS, 90035-903, Brazil. .
Sperb-Ludwig F; Graduate Program in Genetics and Molecular Biology, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, Rio Grande do Sul RS, Brazil.; BRAIN Laboratory, Experimental Research Center, Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, RS, Brazil.
Schwartz IVD; Graduate Program in Genetics and Molecular Biology, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, Rio Grande do Sul RS, Brazil.; BRAIN Laboratory, Experimental Research Center, Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, RS, Brazil.; Genetics Department, Biosciences Institute, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil.; Medical Genetics Department, HCPA, Porto Alegre, RS, Brazil.
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Źródło :
Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2020 Sep; Vol. 77 (17), pp. 3465-3466. Date of Electronic Publication: 2020 Jun 26.
Typ publikacji :
Journal Article; Comment
MeSH Terms :
Fructose Intolerance*
Non-alcoholic Fatty Liver Disease*
Fructose ; Humans
Czasopismo naukowe
Tytuł :
The association of subchronic exposure to low concentration of PM 2.5 and high-fat diet potentiates glucose intolerance development, by impairing adipose tissue antioxidant defense and eHSP72 levels.
Autorzy :
Costa Beber LC; Research Group in Physiology, Department of Life Sciences, Regional University of Northwestern Rio Grande do Sul State (UNIJUI), Rua do Comércio, 3000 - Bairro Universitário -, Ijuí, RS, 98700-000, Brazil. .; Postgraduate Program in Integral Attention to Health (PPGAIS-UNIJUÍ/UNICRUZ), Ijuí, RS, Brazil. .
da Silva MOAF; Research Group in Physiology, Department of Life Sciences, Regional University of Northwestern Rio Grande do Sul State (UNIJUI), Rua do Comércio, 3000 - Bairro Universitário -, Ijuí, RS, 98700-000, Brazil.
Dos Santos AB; Research Group in Physiology, Department of Life Sciences, Regional University of Northwestern Rio Grande do Sul State (UNIJUI), Rua do Comércio, 3000 - Bairro Universitário -, Ijuí, RS, 98700-000, Brazil.; Postgraduate Program in Integral Attention to Health (PPGAIS-UNIJUÍ/UNICRUZ), Ijuí, RS, Brazil.
Mai AS; Research Group in Physiology, Department of Life Sciences, Regional University of Northwestern Rio Grande do Sul State (UNIJUI), Rua do Comércio, 3000 - Bairro Universitário -, Ijuí, RS, 98700-000, Brazil.; Postgraduate Program in Integral Attention to Health (PPGAIS-UNIJUÍ/UNICRUZ), Ijuí, RS, Brazil.
Goettems-Fiorin PB; Research Group in Physiology, Department of Life Sciences, Regional University of Northwestern Rio Grande do Sul State (UNIJUI), Rua do Comércio, 3000 - Bairro Universitário -, Ijuí, RS, 98700-000, Brazil.; Atmospheric Pollution Laboratory, Postgraduate Program in Health Sciences, Federal University of Health Sciences of Porto Alegre (UFCSPA), Rua Sarmento Leite, Porto Alegre, RS, 245, Brazil.
Frizzo MN; Research Group in Physiology, Department of Life Sciences, Regional University of Northwestern Rio Grande do Sul State (UNIJUI), Rua do Comércio, 3000 - Bairro Universitário -, Ijuí, RS, 98700-000, Brazil.; Postgraduate Program in Integral Attention to Health (PPGAIS-UNIJUÍ/UNICRUZ), Ijuí, RS, Brazil.
Hirsch GE; Research Group in Physiology, Department of Life Sciences, Regional University of Northwestern Rio Grande do Sul State (UNIJUI), Rua do Comércio, 3000 - Bairro Universitário -, Ijuí, RS, 98700-000, Brazil.; Postgraduate Program in Integral Attention to Health (PPGAIS-UNIJUÍ/UNICRUZ), Ijuí, RS, Brazil.
Ludwig MS; Research Group in Physiology, Department of Life Sciences, Regional University of Northwestern Rio Grande do Sul State (UNIJUI), Rua do Comércio, 3000 - Bairro Universitário -, Ijuí, RS, 98700-000, Brazil.; Postgraduate Program in Integral Attention to Health (PPGAIS-UNIJUÍ/UNICRUZ), Ijuí, RS, Brazil.
Heck TG; Research Group in Physiology, Department of Life Sciences, Regional University of Northwestern Rio Grande do Sul State (UNIJUI), Rua do Comércio, 3000 - Bairro Universitário -, Ijuí, RS, 98700-000, Brazil.; Postgraduate Program in Integral Attention to Health (PPGAIS-UNIJUÍ/UNICRUZ), Ijuí, RS, Brazil.
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Źródło :
Environmental science and pollution research international [Environ Sci Pollut Res Int] 2020 Sep; Vol. 27 (25), pp. 32006-32016. Date of Electronic Publication: 2020 Jun 06.
Typ publikacji :
Journal Article
MeSH Terms :
Glucose Intolerance*
Insulin Resistance*
Adipose Tissue ; Animals ; Antioxidants ; Diet, High-Fat ; Male ; Mice ; Mice, Inbred C57BL ; Particulate Matter
Czasopismo naukowe
Tytuł :
Baseline characteristics and risk factors for short-term outcomes in 132 COVID-19 patients with diabetes in Wuhan China: A retrospective study.
Autorzy :
Li Y; Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China; Hubei Province Key Laboratory of Molecular Imaging, Wuhan 430022, China.
Han X; Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China; Hubei Province Key Laboratory of Molecular Imaging, Wuhan 430022, China.
Alwalid O; Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China; Hubei Province Key Laboratory of Molecular Imaging, Wuhan 430022, China.
Cui Y; Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China; Hubei Province Key Laboratory of Molecular Imaging, Wuhan 430022, China.
Cao Y; Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China; Hubei Province Key Laboratory of Molecular Imaging, Wuhan 430022, China.
Liu J; Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China; Hubei Province Key Laboratory of Molecular Imaging, Wuhan 430022, China.
Gu J; Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China; Hubei Province Key Laboratory of Molecular Imaging, Wuhan 430022, China.
Wang L; Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China; Hubei Province Key Laboratory of Molecular Imaging, Wuhan 430022, China. Electronic address: .
Fan Y; Department of Radiology, Wuhan Jinyintan Hospital, No.1 Yintan Road, Dongxihu District, Wuhan 430022, China. Electronic address: .
Shi H; Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China; Hubei Province Key Laboratory of Molecular Imaging, Wuhan 430022, China. Electronic address: .
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Źródło :
Diabetes research and clinical practice [Diabetes Res Clin Pract] 2020 Aug; Vol. 166, pp. 108299. Date of Electronic Publication: 2020 Jul 03.
Typ publikacji :
Journal Article
MeSH Terms :
Betacoronavirus/*isolation & purification
Blood Glucose/*metabolism
Coronavirus Infections/*mortality
Diabetes Complications/*mortality
Diabetes Mellitus/*physiopathology
Glucose Intolerance/*complications
Hyperglycemia/*complications
Pneumonia, Viral/*mortality
Aged ; COVID-19 ; China/epidemiology ; Coronavirus Infections/complications ; Coronavirus Infections/transmission ; Coronavirus Infections/virology ; Diabetes Complications/epidemiology ; Diabetes Complications/virology ; Diabetes Mellitus/virology ; Female ; Glucose Intolerance/virology ; Hospitalization/statistics & numerical data ; Humans ; Hyperglycemia/virology ; Intensive Care Units ; Male ; Middle Aged ; Pandemics ; Patient Discharge/statistics & numerical data ; Pneumonia, Viral/complications ; Pneumonia, Viral/transmission ; Pneumonia, Viral/virology ; Prognosis ; Retrospective Studies ; Risk Factors ; SARS-CoV-2 ; Survival Rate
Czasopismo naukowe
Tytuł :
Dietary Cyanidin-3-Glucoside Attenuates High-Fat-Diet-Induced Body-Weight Gain and Impairment of Glucose Tolerance in Mice via Effects on the Hepatic Hormone FGF21.
Autorzy :
Tian L; Division of Advanced Diagnostics, Toronto General Hospital Research Institute, University Health Network, Toronto, Canada.; Department of Physiology, University of Toronto, Toronto, Canada.; Banting and Best Diabetes Centre, Faculty of Medicine, University of Toronto, Toronto, Canada.
Ning H; Division of Advanced Diagnostics, Toronto General Hospital Research Institute, University Health Network, Toronto, Canada.; Henan Institute of Science and Technology, Xinxiang, Henan, China.
Shao W; Division of Advanced Diagnostics, Toronto General Hospital Research Institute, University Health Network, Toronto, Canada.; Department of Physiology, University of Toronto, Toronto, Canada.; Banting and Best Diabetes Centre, Faculty of Medicine, University of Toronto, Toronto, Canada.
Song Z; Division of Advanced Diagnostics, Toronto General Hospital Research Institute, University Health Network, Toronto, Canada.; Department of Physiology, University of Toronto, Toronto, Canada.; Banting and Best Diabetes Centre, Faculty of Medicine, University of Toronto, Toronto, Canada.
Badakhshi Y; Division of Advanced Diagnostics, Toronto General Hospital Research Institute, University Health Network, Toronto, Canada.; Department of Physiology, University of Toronto, Toronto, Canada.; Banting and Best Diabetes Centre, Faculty of Medicine, University of Toronto, Toronto, Canada.
Ling W; Department of Nutrition, School of Public Health, Sun Yet-Sen University, Guangzhou, China.
Yang BB; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada.
Brubaker PL; Department of Physiology, University of Toronto, Toronto, Canada.; Department of Medicine, University of Toronto, Toronto, Canada.
Jin T; Division of Advanced Diagnostics, Toronto General Hospital Research Institute, University Health Network, Toronto, Canada.; Department of Physiology, University of Toronto, Toronto, Canada.; Banting and Best Diabetes Centre, Faculty of Medicine, University of Toronto, Toronto, Canada.; Department of Medicine, University of Toronto, Toronto, Canada.
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Źródło :
The Journal of nutrition [J Nutr] 2020 Aug 01; Vol. 150 (8), pp. 2101-2111.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Glucose Intolerance*
Anthocyanins/*pharmacology
Diet, High-Fat/*adverse effects
Dietary Fats/*administration & dosage
Fibroblast Growth Factors/*metabolism
Glucosides/*pharmacology
Weight Gain/*drug effects
Animals ; Dietary Fats/adverse effects ; Fibroblast Growth Factors/genetics ; Gene Expression Regulation/drug effects ; Glucagon-Like Peptide 1/metabolism ; Incretins/genetics ; Incretins/metabolism ; Leptin/metabolism ; Liver ; Male ; Mice ; Random Allocation ; Weight Loss/drug effects
Czasopismo naukowe
Tytuł :
Assessment of Glycemic status, Insulin Resistance and Hypogonadism in HIV Infected Male Patients.
Autorzy :
Bajaj S; Director, Professor and Head, Department of Medicine, MLN Medical College, Prayagaraj, Uttar Pradesh.
Sonkar KK; Associate Professor, Department of Medicine, MLN Medical College, Prayagaraj, Uttar Pradesh.
Verma S; Associate Professor, Department of Medicine, MLN Medical College, Prayagaraj, Uttar Pradesh.
Varma S; Senior Medical Officer, ART Centre, Department of Medicine, MLN Medical College, Prayagaraj, Uttar Pradesh.
Singh AK; Junior Resident, Department of Medicine, MLN Medical College, Prayagaraj, Uttar Pradesh.
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Źródło :
The Journal of the Association of Physicians of India [J Assoc Physicians India] 2020 Aug; Vol. 68 (8), pp. 43-46.
Typ publikacji :
Journal Article
MeSH Terms :
Diabetes Mellitus, Type 2*
Glucose Intolerance*
HIV Infections*
Hypogonadism*
Insulin Resistance*
Adolescent ; Adult ; Aged ; Blood Glucose ; Case-Control Studies ; Fasting ; Glucose Tolerance Test ; Humans ; Insulin ; Male ; Middle Aged ; Young Adult
Czasopismo naukowe
Tytuł :
Pitfalls in the Diagnosis of Hereditary Fructose Intolerance.
Autorzy :
Kim AY; Department of Genetic Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland; and .
Hughes JJ; National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland.
Pipitone Dempsey A; Department of Genetic Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland; and.
Sondergaard Schatz K; Department of Genetic Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland; and.
Wang T; Department of Genetic Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland; and.
Gunay-Aygun M; Department of Genetic Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland; and.
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Źródło :
Pediatrics [Pediatrics] 2020 Aug; Vol. 146 (2).
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Fructose Intolerance/*diagnosis
Adult ; Aged ; Asymptomatic Diseases ; Child ; Child, Preschool ; Developmental Disabilities/genetics ; Direct-To-Consumer Screening and Testing ; Dwarfism/genetics ; Failure to Thrive/genetics ; Female ; Food Preferences ; Fructose Intolerance/genetics ; Fructose-Bisphosphate Aldolase/genetics ; Fruit/adverse effects ; Genetic Testing ; Humans ; Incidental Findings ; Infertility, Female ; Male ; Preconception Care ; Vegetables/adverse effects ; Whole Exome Sequencing
Czasopismo naukowe
Tytuł :
Differential unfolded protein response in skeletal muscle from non-diabetic glucose tolerant or intolerant patients with obesity before and after bariatric surgery.
Autorzy :
Marciniak C; Univ. Lille, Inserm, CHU Lille, U1190 - EGID, F-59000, Lille, France.
Duhem C; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011 - EGID, F-59000, Lille, France.
Boulinguiez A; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011 - EGID, F-59000, Lille, France.
Raverdy V; Univ. Lille, Inserm, CHU Lille, U1190 - EGID, F-59000, Lille, France.
Baud G; Univ. Lille, Inserm, CHU Lille, U1190 - EGID, F-59000, Lille, France.
Verkindt H; Univ. Lille, Inserm, CHU Lille, U1190 - EGID, F-59000, Lille, France.
Caiazzo R; Univ. Lille, Inserm, CHU Lille, U1190 - EGID, F-59000, Lille, France.
Staels B; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011 - EGID, F-59000, Lille, France.
Duez H; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011 - EGID, F-59000, Lille, France.
Pattou F; Univ. Lille, Inserm, CHU Lille, U1190 - EGID, F-59000, Lille, France.
Lancel S; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011 - EGID, F-59000, Lille, France. .
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Źródło :
Acta diabetologica [Acta Diabetol] 2020 Jul; Vol. 57 (7), pp. 819-826. Date of Electronic Publication: 2020 Feb 21.
Typ publikacji :
Journal Article
MeSH Terms :
Bariatric Surgery*
Unfolded Protein Response*
Glucose Intolerance/*surgery
Muscle, Skeletal/*metabolism
Obesity, Morbid/*surgery
Activating Transcription Factor 6/genetics ; Activating Transcription Factor 6/metabolism ; Adult ; Biopsy ; Blood Glucose/metabolism ; Case-Control Studies ; Cohort Studies ; Endoplasmic Reticulum Stress/genetics ; Endoplasmic Reticulum Stress/physiology ; Female ; Gene Expression Regulation ; Glucose Intolerance/complications ; Glucose Intolerance/metabolism ; Glucose Intolerance/pathology ; Glucose Tolerance Test ; Humans ; Insulin Resistance/physiology ; Male ; Muscle, Skeletal/pathology ; Obesity, Morbid/complications ; Obesity, Morbid/metabolism ; Obesity, Morbid/pathology ; Transcription Factor CHOP/genetics ; Transcription Factor CHOP/metabolism
Czasopismo naukowe
Tytuł :
Diagnostic Utility of Carbohydrate Breath Tests for SIBO, Fructose, and Lactose Intolerance.
Autorzy :
Amieva-Balmori M; Division of Gastroenterology and Hepatology, Department of Medicine, Augusta University, 1120 15th Street, Augusta, GA, 30912, USA.; Universidad Veracruzana, Veracruz, Mexico.
Coss-Adame E; Division of Gastroenterology and Hepatology, Department of Medicine, Augusta University, 1120 15th Street, Augusta, GA, 30912, USA.; Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubiran, Mexico City, Mexico.
Rao NS; Division of Gastroenterology and Hepatology, Department of Medicine, Augusta University, 1120 15th Street, Augusta, GA, 30912, USA.
Dávalos-Pantoja BM; Division of Gastroenterology and Hepatology, Department of Medicine, Augusta University, 1120 15th Street, Augusta, GA, 30912, USA.
Rao SSC; Division of Gastroenterology and Hepatology, Department of Medicine, Augusta University, 1120 15th Street, Augusta, GA, 30912, USA. .
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Źródło :
Digestive diseases and sciences [Dig Dis Sci] 2020 May; Vol. 65 (5), pp. 1405-1413. Date of Electronic Publication: 2019 Oct 15.
Typ publikacji :
Evaluation Study; Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Blind Loop Syndrome/*diagnosis
Breath Tests/*methods
Carbohydrates/*analysis
Fructose Metabolism, Inborn Errors/*diagnosis
Lactose Intolerance/*diagnosis
Adult ; Blind Loop Syndrome/epidemiology ; Diagnosis, Differential ; Female ; Fructose/analysis ; Fructose Metabolism, Inborn Errors/epidemiology ; Glucose/analysis ; Humans ; Lactose/analysis ; Lactose Intolerance/epidemiology ; Male ; Middle Aged ; Predictive Value of Tests ; Prevalence
Czasopismo naukowe
Tytuł :
Recent advances in the pathogenesis of hereditary fructose intolerance: implications for its treatment and the understanding of fructose-induced non-alcoholic fatty liver disease.
Autorzy :
Buziau AM; Division of Endocrinology, Department of Internal Medicine, Maastricht University Medical Center, Maastricht, The Netherlands.; Laboratory for Metabolism and Vascular Medicine, Division of General Internal Medicine, Department of Internal Medicine, Maastricht University Medical Center, Maastricht, The Netherlands.; Cardiovascular Research Institute Maastricht (CARIM), Maastricht, The Netherlands.
Schalkwijk CG; Laboratory for Metabolism and Vascular Medicine, Division of General Internal Medicine, Department of Internal Medicine, Maastricht University Medical Center, Maastricht, The Netherlands.; Cardiovascular Research Institute Maastricht (CARIM), Maastricht, The Netherlands.
Stehouwer CDA; Laboratory for Metabolism and Vascular Medicine, Division of General Internal Medicine, Department of Internal Medicine, Maastricht University Medical Center, Maastricht, The Netherlands.; Cardiovascular Research Institute Maastricht (CARIM), Maastricht, The Netherlands.; Division of General Internal Medicine, Department of Internal Medicine, Maastricht University Medical Center, Maastricht, The Netherlands.
Tolan DR; Department of Biology, Boston University, Boston, MA, USA. .
Brouwers MCGJ; Division of Endocrinology, Department of Internal Medicine, Maastricht University Medical Center, Maastricht, The Netherlands. .; Laboratory for Metabolism and Vascular Medicine, Division of General Internal Medicine, Department of Internal Medicine, Maastricht University Medical Center, Maastricht, The Netherlands. .; Cardiovascular Research Institute Maastricht (CARIM), Maastricht, The Netherlands. .
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Źródło :
Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2020 May; Vol. 77 (9), pp. 1709-1719. Date of Electronic Publication: 2019 Nov 12.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Genetic Predisposition to Disease*
Fructose/*adverse effects
Fructose Intolerance/*pathology
Non-alcoholic Fatty Liver Disease/*pathology
Animals ; Fructose/metabolism ; Fructose Intolerance/drug therapy ; Fructose Intolerance/etiology ; Humans ; Mice ; Non-alcoholic Fatty Liver Disease/chemically induced ; Non-alcoholic Fatty Liver Disease/drug therapy
Czasopismo naukowe
Tytuł :
Lactose Intolerance: A Concise Review to Skim the Surface.
Autorzy :
Jansson-Knodell CL; Division of Gastroenterology and Hepatology, Indiana University, Indianapolis, IN.
Krajicek EJ; Division of Gastroenterology and Hepatology, Indiana University, Indianapolis, IN.
Savaiano DA; Department of Nutrition Science, Purdue University, West Lafayette, IN.
Shin AS; Division of Gastroenterology and Hepatology, Indiana University, Indianapolis, IN. Electronic address: .
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Źródło :
Mayo Clinic proceedings [Mayo Clin Proc] 2020 Jul; Vol. 95 (7), pp. 1499-1505.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Lactose Intolerance*/diagnosis
Lactose Intolerance*/genetics
Lactose Intolerance*/physiopathology
Lactose Intolerance*/therapy
Dairy Products/adverse effects ; Dairy Products/analysis ; Humans
Czasopismo naukowe
Tytuł :
Prediction of Persistent Impaired Glucose Tolerance in Patients with Minor Ischemic Stroke or Transient Ischemic Attack.
Autorzy :
Osei E; Flevoziekenhuis, Almere, the Netherland. Electronic address: .
den Hertog HM; Isala, Zwolle, the Netherlands.
Fonville S; Spaarne Gasthuis, Haarlem, the Netherlands.
Brouwers PJAM; Medisch Spectrum Twente, Enschede, the Netherlands.
Mulder LJMM; Ikazia Ziekenhuis, Rotterdam, the Netherlands.
Koudstaal PJ; Erasmus Medical Center, Rotterdam, the Netherlands.
Dippel DWJ; Erasmus Medical Center, Rotterdam, the Netherlands.
Zandbergen AAM; Erasmus Medical Center, Rotterdam, the Netherlands.
Lingsma HF; Erasmus Medical Center, Rotterdam, the Netherlands.
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Źródło :
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association [J Stroke Cerebrovasc Dis] 2020 Jun; Vol. 29 (6), pp. 104815. Date of Electronic Publication: 2020 Apr 14.
Typ publikacji :
Journal Article; Validation Study
MeSH Terms :
Decision Support Techniques*
Glucose Tolerance Test*
Blood Glucose/*metabolism
Glucose Intolerance/*blood
Ischemic Attack, Transient/*blood
Stroke/*blood
Aged ; Aged, 80 and over ; Biomarkers/blood ; Female ; Glucose Intolerance/diagnosis ; Glucose Intolerance/physiopathology ; Glucose Intolerance/therapy ; Humans ; Ischemic Attack, Transient/diagnosis ; Ischemic Attack, Transient/physiopathology ; Ischemic Attack, Transient/prevention & control ; Male ; Middle Aged ; Predictive Value of Tests ; Prognosis ; Prospective Studies ; Recurrence ; Reproducibility of Results ; Risk Assessment ; Risk Factors ; Secondary Prevention ; Stroke/diagnosis ; Stroke/physiopathology ; Stroke/prevention & control ; Time Factors
Czasopismo naukowe

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