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Wyszukujesz frazę ""Intracellular Signaling Peptides and Proteins metabolism"" wg kryterium: Temat


Tytuł :
Autophagy induction by histone deacetylase inhibitors inhibits HIV type 1
Autorzy :
Campbell, GR
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Index Terms :
Autophagy: drug effects
Female
HIV Infections: drug therapy
enzymology
pathology
HIV-1: physiology
Histone Deacetylase Inhibitors: pharmacology
Humans
Intracellular Signaling Peptides and Proteins: metabolism
Lysosomes: pathology
virology
Macrophages: enzymology
Male
Protein-Serine-Threonine Kinases: metabolism
TOR Serine-Threonine Kinases: metabolism
Virus Latency: drug effects
article
Źródło :
Journal of Biological Chemistry vol 290, iss 8, 5028-5040 0021-9258
URL :
https://escholarship.org/uc/item/78z3d9mb">https://escholarship.org/uc/item/78z3d9mb
https://escholarship.org/">https://escholarship.org/
Zasób elektroniczny
Tytuł :
Live-cell imaging of receptors around postsynaptic membranes.
Index Terms :
Cell Culture Techniques
Cell Membrane/metabolism
HEK293 Cells
Humans
Intracellular Signaling Peptides and Proteins/metabolism
Membrane Proteins/metabolism
Nerve Tissue Proteins/metabolism
Neuronal Plasticity
Optical Imaging/methods
Receptors, Glutamate/metabolism
Journal Article
URL :
http://hdl.handle.net/2433/196745">http://hdl.handle.net/2433/196745
10.1038/nprot.2013.171
Zasób elektroniczny
Tytuł :
Autophagy induction by histone deacetylase inhibitors inhibits HIV type 1.
Index Terms :
Life Sciences
Autophagy: drug effects
Female
HIV Infections: drug therapy; enzymology; pathology
HIV-1: physiology
Histone Deacetylase Inhibitors: pharmacology
Humans
Intracellular Signaling Peptides and Proteins: metabolism
Lysosomes: pathology; virology
Macrophages: enzymology; pathology; virology
Male
Protein-Serine-Threonine Kinases: metabolism
TOR Serine-Threonine Kinases: metabolism
Virus Latency: drug effects
article
Źródło :
The Journal of Biological Chemistry vol 290, no 8, 5028-5040; 1083-351X
URL :
http://www.escholarship.org/uc/item/78z3d9mb">http://www.escholarship.org/uc/item/78z3d9mb
Zasób elektroniczny
Tytuł :
Autophagy induction by histone deacetylase inhibitors inhibits HIV type 1.
Index Terms :
Life Sciences
Autophagy: drug effects
Female
HIV Infections: drug therapy; enzymology; pathology
HIV-1: physiology
Histone Deacetylase Inhibitors: pharmacology
Humans
Intracellular Signaling Peptides and Proteins: metabolism
Lysosomes: pathology; virology
Macrophages: enzymology; pathology; virology
Male
Protein-Serine-Threonine Kinases: metabolism
TOR Serine-Threonine Kinases: metabolism
Virus Latency: drug effects
article
Źródło :
The Journal of Biological Chemistry vol 290, no 8, 5028-5040; 1083-351X
URL :
http://www.escholarship.org/uc/item/19z491cc">http://www.escholarship.org/uc/item/19z491cc
Zasób elektroniczny
Tytuł :
Targeting myristoylated alanine-rich C kinase substrate phosphorylation site domain in lung cancer. Mechanisms and therapeutic implications.
Autorzy :
Chen, Ching-Hsien
Pokaż więcej
Index Terms :
Animals
Cell Culture Techniques
Cell Line
Tumor
Disease Models
Animal
Humans
Intracellular Signaling Peptides and Proteins: metabolism
Lung Neoplasms: drug therapy
metabolism
pathology
Membrane Proteins: metabolism
Mice
Phosphatidylinositol 3-Kinase: metabolism
Phosphatidylinositol Phosphates: metabolism
Phosphorylation: physiology
Protein Kinase Inhibitors: therapeutic use
Quinazolines: therapeutic use
Signal Transduction: physiology
article
Źródło :
American journal of respiratory and critical care medicine vol 190, iss 10, 1127-1138 1535-4970
URL :
https://escholarship.org/uc/item/7jm9t4vv">https://escholarship.org/uc/item/7jm9t4vv
https://escholarship.org/">https://escholarship.org/
Zasób elektroniczny
Tytuł :
Targeting myristoylated alanine-rich C kinase substrate phosphorylation site domain in lung cancer. Mechanisms and therapeutic implications.
Index Terms :
Medicine and Health Sciences
Animals
Cell Culture Techniques
Cell Line, Tumor
Disease Models, Animal
Humans
Intracellular Signaling Peptides and Proteins: metabolism
Lung Neoplasms: drug therapy; metabolism; pathology
Membrane Proteins: metabolism
Mice
Phosphatidylinositol 3-Kinase: metabolism
Phosphatidylinositol Phosphates: metabolism
Phosphorylation: physiology
Protein Kinase Inhibitors: therapeutic use
Quinazolines: therapeutic use
Signal Transduction: physiology
article
Źródło :
American journal of respiratory and critical care medicine vol 190, no 10, 1127-1138; 1535-4970
URL :
http://www.escholarship.org/uc/item/7jm9t4vv">http://www.escholarship.org/uc/item/7jm9t4vv
Zasób elektroniczny
Tytuł :
Arabidopsis SABRE and CLASP interact to stabilize cell division plane orientation and planar polarity
Index Terms :
Arabidopsis/cytology; Arabidopsis/physiology; Arabidopsis Proteins/genetics; Arabidopsis Proteins/metabolism; Cell Division/physiology; Cell Polarity/physiology; Gene Expression Regulation, Plant/physiology; Intracellular Signaling Peptides and Proteins/genetics; Intracellular Signaling Peptides and Proteins/metabolism; Microtubule-Associated Proteins/genetics; Microtubule-Associated Proteins/metabolism
info:eu-repo/semantics/article
article
URL :
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_84A51323B2E35">http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_84A51323B2E35
Zasób elektroniczny
Tytuł :
Overfeeding reduces insulin sensitivity and increases oxidative stress, without altering markers of mitochondrial content and function in humans
Index Terms :
Adult Biopsy Blood Glucose Body Weight Citrate (si)-Synthase/metabolism Cohort Studies *Diabetes Mellitus, Type 2/metabolism/physiopathology Diet, High-Fat Female Humans *Insulin/blood *Insulin Resistance Intracellular Signaling Peptides and Proteins/metabolism Lipid Metabolism Male Mitochondria/metabolism/physiology Muscle, Skeletal/enzymology/metabolism *Obesity/metabolism/pathology *Oxidative Stress Weight Gain/physiology
110306 Endocrinology
text
Journal Article
JOUR
URL :
http://handle.unsw.edu.au/1959.4/unsworks_36309">http://handle.unsw.edu.au/1959.4/unsworks_36309
http://www.ncbi.nlm.nih.gov/pubmed/22586466">http://www.ncbi.nlm.nih.gov/pubmed/22586466
https://orcid.org/0000-0001-9422-7852">https://orcid.org/0000-0001-9422-7852
https://orcid.org/0000-0002-0866-0973">https://orcid.org/0000-0002-0866-0973
https://orcid.org/0000-0002-0119-9328">https://orcid.org/0000-0002-0119-9328
Samocha-Bonet, Dorit Campbell, Lesley V Mori, Trevor A Croft, Kevin D Greenfield, Jerry R Turner, Nigel Heilbronn, Leonie K PLoS One. 2012;7(5):e36320. Epub 2012 May 7.BACKGROUND: Mitochondrial dysfunction and increased oxidative stress are associated with obesity and type 2 diabetes. High fat feeding induces insulin resistance and increases skeletal muscle oxidative stress in rodents, but there is controversy as to whether skeletal muscle mitochondrial biogenesis and function is altered. METHODOLOGY AND PRINCIPAL FINDINGS: Forty (37 +/- 2 y) non-obese (25.6 +/- 0.6 kg/m(2)) sedentary men (n = 20) and women (n = 20) were overfed (+1040 +/- 100 kcal/day, 46 +/- 1% of energy from fat) for 28 days. Hyperinsulinemic-euglycemic clamps were performed at baseline and day 28 of overfeeding and skeletal muscle biopsies taken at baseline, day 3 and day 28 of overfeeding in a sub cohort of 26 individuals (13 men and 13 women) that consented to having all 3 biopsies performed. Weight increased on average in the whole cohort by 0.6 +/- 0.1 and 2.7 +/- 0.3 kg at days 3 and 28, respectively (P<0.0001, without a significant difference in the response between men and women (P = 0.4). Glucose infusion rate during the hyperinsulinemic-euglycemic clamp decreased from 54.8 +/- 2.8 at baseline to 50.3 +/- 2.5 micromol/min/kg FFM at day 28 of overfeeding (P = 0.03) without a significant difference between men and women (P = 0.4). Skeletal muscle protein carbonyls and urinary F2-isoprostanes increased with overfeeding (P<0.05). Protein levels of muscle peroxisome proliferator-activated receptor gamma coactivator-1alpha (PGC1alpha) and subunits from complex I, II and V of the electron transport chain were increased at day 3 (all P<0.05) and returned to basal levels at day 28. No changes were detected in muscle citrate synthase activity or ex vivo CO(2) production at either time point. CONCLUSIONS: Peripheral insulin resistance was induced by overfeeding, without reducing any of the markers
PLoS One, 7, 5
Zasób elektroniczny
Tytuł :
Phytochrome Kinase Substrate 4 is phosphorylated by the phototropin 1 photoreceptor.
Index Terms :
Arabidopsis/enzymology; Arabidopsis/physiology; Arabidopsis Proteins/metabolism; Intracellular Signaling Peptides and Proteins/metabolism; Phosphoproteins/metabolism; Phosphorylation; Phototrophic Processes; Protein Processing, Post-Translational; Signal Transduction
info:eu-repo/semantics/article
article
URL :
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_D17C87E21DB28">http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_D17C87E21DB28
Zasób elektroniczny

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