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Tytuł :
Characterisation of endogenous Galectin-1 and -9 expression in monocyte and macrophage subsets under resting and inflammatory conditions.
Autorzy :
Krautter F; Institute of Cardiovascular Sciences (ICVS), College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.
Recio C; Instituto Universitario de Investigaciones Biomédicas y Sanitarias (IUIBS), Universidad de Las Palmas de Gran Canaria, Farmacología Molecular y Traslacional - BIOPharm, Las Palmas de G.C, 35016, Spain.
Hussain MT; Institute of Cardiovascular Sciences (ICVS), College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.
Lezama DR; Institute of Cardiovascular Sciences (ICVS), College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.
Maione F; ImmunoPharmaLab, Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131, Naples, Italy. Electronic address: .
Chimen M; Institute of Cardiovascular Sciences (ICVS), College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.
Iqbal AJ; Institute of Cardiovascular Sciences (ICVS), College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom; ImmunoPharmaLab, Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131, Naples, Italy. Electronic address: a.j.iqbal@bham.ac.uk.
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2020 Oct; Vol. 130, pp. 110595. Date of Electronic Publication: 2020 Aug 06.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
The Role and Impact of Extracellular Vesicles in the Modulation and Delivery of Cytokines during Autoimmunity.
Autorzy :
Hussain MT; William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary University of London, London E1 4NS, UK.
Iqbal AJ; The Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, UK.
Norling LV; William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary University of London, London E1 4NS, UK.; Centre for Inflammation and Therapeutic Innovation, Queen Mary University of London, London E1 4NS, UK.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Sep 26; Vol. 21 (19). Date of Electronic Publication: 2020 Sep 26.
Typ publikacji :
Journal Article; Review
Czasopismo naukowe
Tytuł :
The functional link between microsomal prostaglandin E synthase-1 (mPGES-1) and peroxisome proliferator-activated receptor γ (PPARγ) in the onset of inflammation.
Autorzy :
Maione F; ImmunoPharmaLab, Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131, Naples, Italy. Electronic address: .
Casillo GM; ImmunoPharmaLab, Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131, Naples, Italy.
Raucci F; ImmunoPharmaLab, Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131, Naples, Italy.
Iqbal AJ; ImmunoPharmaLab, Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131, Naples, Italy; Institute of Cardiovascular Sciences (ICVS), College of Medical and Dental Sciences, University of Birmingham, Birmingham, B15 2TT, UK.
Mascolo N; ImmunoPharmaLab, Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131, Naples, Italy.
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Źródło :
Pharmacological research [Pharmacol Res] 2020 Jul; Vol. 157, pp. 104807. Date of Electronic Publication: 2020 Apr 22.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Czasopismo naukowe
Tytuł :
Interleukin-17A (IL-17A), a key molecule of innate and adaptive immunity, and its potential involvement in COVID-19-related thrombotic and vascular mechanisms.
Autorzy :
Raucci F; ImmunoPharmaLab, Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131 Naples, Italy.
Mansour AA; Institute of Cardiovascular Sciences (ICVS), College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, UK; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Khalid University, Guraiger, Abha 62529, Saudi Arabia.
Casillo GM; ImmunoPharmaLab, Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131 Naples, Italy.
Saviano A; ImmunoPharmaLab, Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131 Naples, Italy.
Caso F; Rheumatology Research Unit, Department of Clinical Medicine and Surgery, University of Naples Federico II, via S. Pansini 5, 80131 Naples, Italy.
Scarpa R; Rheumatology Research Unit, Department of Clinical Medicine and Surgery, University of Naples Federico II, via S. Pansini 5, 80131 Naples, Italy.
Mascolo N; ImmunoPharmaLab, Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131 Naples, Italy.
Iqbal AJ; Institute of Cardiovascular Sciences (ICVS), College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, UK; ImmunoPharmaLab, Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131 Naples, Italy. Electronic address: A.J.Iqbal@bham.ac.uk.
Maione F; ImmunoPharmaLab, Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131 Naples, Italy. Electronic address: .
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Źródło :
Autoimmunity reviews [Autoimmun Rev] 2020 Jul; Vol. 19 (7), pp. 102572. Date of Electronic Publication: 2020 May 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Coronavirus Infections/*immunology
Endothelium, Vascular/*physiopathology
Interleukin-17/*immunology
Pneumonia, Viral/*immunology
Thrombosis/*physiopathology
Adaptive Immunity ; Betacoronavirus ; Coronavirus Infections/physiopathology ; Humans ; Immunity, Innate ; Pandemics ; Pneumonia, Viral/physiopathology
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Could IL-17 represent a new therapeutic target for the treatment and/or management of COVID-19-related respiratory syndrome?
Autorzy :
Casillo GM; ImmunoPharmaLab, Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131, Naples, Italy.
Mansour AA; Institute of Cardiovascular Sciences (ICVS), College of Medical and Dental Sciences, University of Birmingham, Birmingham, B15 2TT, UK; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Khalid University, Guraiger, Abha, 62529, Saudi Arabia.
Raucci F; ImmunoPharmaLab, Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131, Naples, Italy.
Saviano A; ImmunoPharmaLab, Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131, Naples, Italy.
Mascolo N; ImmunoPharmaLab, Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131, Naples, Italy.
Iqbal AJ; ImmunoPharmaLab, Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131, Naples, Italy; Institute of Cardiovascular Sciences (ICVS), College of Medical and Dental Sciences, University of Birmingham, Birmingham, B15 2TT, UK. Electronic address: A.J.Iqbal@bham.ac.uk.
Maione F; ImmunoPharmaLab, Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131, Naples, Italy. Electronic address: .
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Źródło :
Pharmacological research [Pharmacol Res] 2020 Jun; Vol. 156, pp. 104791. Date of Electronic Publication: 2020 Apr 14.
Typ publikacji :
Letter; Research Support, Non-U.S. Gov't
MeSH Terms :
Betacoronavirus*
Coronavirus Infections/*drug therapy
Interleukin-17/*immunology
Pneumonia, Viral/*drug therapy
Coronavirus Infections/immunology ; Humans ; Pandemics ; Pneumonia, Viral/immunology
SCR Disease Name :
COVID-19
Raport
Tytuł :
Appropriation of GPIbα from platelet-derived extracellular vesicles supports monocyte recruitment in systemic inflammation.
Autorzy :
Chimen M; Institute of Cardiovascular Sciences, College of Medicine and Dentistry, University of Birmingham, Birmingham, UK .; NIHR Surgical Reconstruction and Microbiology Research Centre, Institute of Inflammation and Ageing, Birmingham University Medical School, Birmingham, UK.
Evryviadou A; Institute of Cardiovascular Sciences, College of Medicine and Dentistry, University of Birmingham, Birmingham, UK.
Box CL; Institute of Cardiovascular Sciences, College of Medicine and Dentistry, University of Birmingham, Birmingham, UK.
Harrison MJ; Institute of Cardiovascular Sciences, College of Medicine and Dentistry, University of Birmingham, Birmingham, UK.
Hazeldine J; NIHR Surgical Reconstruction and Microbiology Research Centre, Institute of Inflammation and Ageing, Birmingham University Medical School, Birmingham, UK.
Dib LH; Institute of Cardiovascular Sciences, College of Medicine and Dentistry, University of Birmingham, Birmingham, UK.
Kuravi SJ; Institute of Cardiovascular Sciences, College of Medicine and Dentistry, University of Birmingham, Birmingham, UK.
Payne H; Institute of Cardiovascular Sciences, College of Medicine and Dentistry, University of Birmingham, Birmingham, UK.
Price JMJ; NIHR Surgical Reconstruction and Microbiology Research Centre, Institute of Inflammation and Ageing, Birmingham University Medical School, Birmingham, UK.
Kavanagh D; Institute of Cardiovascular Sciences, College of Medicine and Dentistry, University of Birmingham, Birmingham, UK.
Iqbal AJ; Institute of Cardiovascular Sciences, College of Medicine and Dentistry, University of Birmingham, Birmingham, UK.
Lax S; Institute of Cardiovascular Sciences, College of Medicine and Dentistry, University of Birmingham, Birmingham, UK.
Kalia N; Institute of Cardiovascular Sciences, College of Medicine and Dentistry, University of Birmingham, Birmingham, UK.
Brill A; Institute of Cardiovascular Sciences, College of Medicine and Dentistry, University of Birmingham, Birmingham, UK.; Centre of Membrane Proteins and Receptors, University of Birmingham and Nottingham, The Midlands, UK.; Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.
Thomas SG; Institute of Cardiovascular Sciences, College of Medicine and Dentistry, University of Birmingham, Birmingham, UK.; Centre of Membrane Proteins and Receptors, University of Birmingham and Nottingham, The Midlands, UK.
Belli A; NIHR Surgical Reconstruction and Microbiology Research Centre, Institute of Inflammation and Ageing, Birmingham University Medical School, Birmingham, UK.
Crombie N; NIHR Surgical Reconstruction and Microbiology Research Centre, Institute of Inflammation and Ageing, Birmingham University Medical School, Birmingham, UK.
Adams RA; Cardiff School of Health Sciences, Cardiff Metropolitan University, Cardiff, UK.
Evans SA; Cardiff School of Health Sciences, Cardiff Metropolitan University, Cardiff, UK.
Deckmyn H; Laboratory for Thrombosis Research, KU Leuven Campus Kulak Kortrijk, Kortrijk, Belgium.
Lord JM; NIHR Surgical Reconstruction and Microbiology Research Centre, Institute of Inflammation and Ageing, Birmingham University Medical School, Birmingham, UK.
Harrison P; NIHR Surgical Reconstruction and Microbiology Research Centre, Institute of Inflammation and Ageing, Birmingham University Medical School, Birmingham, UK.
Watson SP; Institute of Cardiovascular Sciences, College of Medicine and Dentistry, University of Birmingham, Birmingham, UK.; Centre of Membrane Proteins and Receptors, University of Birmingham and Nottingham, The Midlands, UK.
Nash GB; Institute of Cardiovascular Sciences, College of Medicine and Dentistry, University of Birmingham, Birmingham, UK.
Rainger GE; Institute of Cardiovascular Sciences, College of Medicine and Dentistry, University of Birmingham, Birmingham, UK.
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Źródło :
Haematologica [Haematologica] 2020 May; Vol. 105 (5), pp. 1248-1261. Date of Electronic Publication: 2019 Aug 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Czasopismo naukowe
Tytuł :
A Pro-resolving Role for Galectin-1 in Acute Inflammation.
Autorzy :
Law HL; The William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.
Wright RD; The William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.; Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom.
Iqbal AJ; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.
Norling LV; The William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.; Centre for Inflammation and Therapeutic Innovation, Queen Mary University of London, London, United Kingdom.
Cooper D; The William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.; Centre for Inflammation and Therapeutic Innovation, Queen Mary University of London, London, United Kingdom.
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Źródło :
Frontiers in pharmacology [Front Pharmacol] 2020 Mar 20; Vol. 11, pp. 274. Date of Electronic Publication: 2020 Mar 20 (Print Publication: 2020).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Temporin L-derived peptide as a regulator of the acute inflammatory response in zymosan-induced peritonitis.
Autorzy :
Bellavita R; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131, Naples, Italy.
Raucci F; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131, Naples, Italy.
Merlino F; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131, Naples, Italy.
Piccolo M; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131, Naples, Italy.
Ferraro MG; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131, Naples, Italy.
Irace C; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131, Naples, Italy.
Santamaria R; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131, Naples, Italy.
Iqbal AJ; Institute of Cardiovascular Sciences (ICVS), College of Medical and Dental Sciences, University of Birmingham, Birmingham, B15 2TT, UK.
Novellino E; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131, Naples, Italy.
Grieco P; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131, Naples, Italy. Electronic address: .
Mascolo N; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131, Naples, Italy.
Maione F; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131, Naples, Italy. Electronic address: .
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2020 Mar; Vol. 123, pp. 109788. Date of Electronic Publication: 2019 Dec 25.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Anti-Inflammatory Agents/*pharmacology
Antimicrobial Cationic Peptides/*pharmacology
Inflammation/*drug therapy
Peritonitis/*drug therapy
Acute Disease ; Animals ; Anti-Inflammatory Agents/chemistry ; Antimicrobial Cationic Peptides/chemistry ; Cell Line ; Disease Models, Animal ; Inflammation/pathology ; Inflammation Mediators/metabolism ; Male ; Mice ; Monocytes/drug effects ; Monocytes/pathology ; Peritonitis/pathology ; Zymosan
Czasopismo naukowe
Tytuł :
The Impact of Cannabinoid Receptor 2 Deficiency on Neutrophil Recruitment and Inflammation.
Autorzy :
Hussain MT; Institute of Cardiovascular Sciences (ICVS), College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.
Greaves DR; Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom.
Iqbal AJ; Institute of Cardiovascular Sciences (ICVS), College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.
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Źródło :
DNA and cell biology [DNA Cell Biol] 2019 Oct; Vol. 38 (10), pp. 1025-1029. Date of Electronic Publication: 2019 Sep 18.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Atherosclerosis/*genetics
Colitis/*genetics
Multiple Sclerosis/*genetics
Neutrophils/*metabolism
Receptor, Cannabinoid, CB2/*genetics
Reperfusion Injury/*genetics
Animals ; Atherosclerosis/drug therapy ; Atherosclerosis/metabolism ; Atherosclerosis/pathology ; Cannabinoid Receptor Agonists/therapeutic use ; Cannabinoid Receptor Antagonists/therapeutic use ; Colitis/drug therapy ; Colitis/metabolism ; Colitis/pathology ; Cytokines/metabolism ; Cytokines/pharmacology ; Disease Models, Animal ; Gene Expression Regulation ; Humans ; Inflammation ; Ligands ; Mice ; Mice, Knockout ; Multiple Sclerosis/drug therapy ; Multiple Sclerosis/metabolism ; Multiple Sclerosis/pathology ; Neutrophil Infiltration ; Neutrophils/drug effects ; Neutrophils/pathology ; Receptor, Cannabinoid, CB2/agonists ; Receptor, Cannabinoid, CB2/antagonists & inhibitors ; Receptor, Cannabinoid, CB2/deficiency ; Reperfusion Injury/drug therapy ; Reperfusion Injury/metabolism ; Reperfusion Injury/pathology
Czasopismo naukowe
Tytuł :
Neutralization of IL-17 rescues amyloid-β-induced neuroinflammation and memory impairment.
Autorzy :
Cristiano C; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Naples, Italy.
Volpicelli F; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Naples, Italy.; Institute of Genetics and Biophysics 'Adriano Buzzati Traverso,' Developmental Biology and Genetics division, CNR, Naples, Italy.
Lippiello P; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Naples, Italy.
Buono B; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Naples, Italy.
Raucci F; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Naples, Italy.
Piccolo M; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Naples, Italy.
Iqbal AJ; Institute of Cardiovascular Sciences (ICVS), College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Irace C; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Naples, Italy.
Miniaci MC; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Naples, Italy.
Perrone Capano C; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Naples, Italy.; Institute of Genetics and Biophysics 'Adriano Buzzati Traverso,' Developmental Biology and Genetics division, CNR, Naples, Italy.
Calignano A; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Naples, Italy.
Mascolo N; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Naples, Italy.
Maione F; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Naples, Italy.
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Źródło :
British journal of pharmacology [Br J Pharmacol] 2019 Sep; Vol. 176 (18), pp. 3544-3557. Date of Electronic Publication: 2019 Mar 03.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Inflammatory Agents/*therapeutic use
Antibodies, Neutralizing/*therapeutic use
Interleukin-17/*immunology
Memory Disorders/*drug therapy
Neurodegenerative Diseases/*drug therapy
Neuroprotective Agents/*therapeutic use
Amyloid beta-Peptides ; Animals ; Behavior, Animal/drug effects ; Brain/drug effects ; Brain/metabolism ; Male ; Maze Learning/drug effects ; Memory Disorders/metabolism ; Mice ; Neurodegenerative Diseases/metabolism ; Peptide Fragments
Czasopismo naukowe
Tytuł :
IL-17A neutralizing antibody regulates monosodium urate crystal-induced gouty inflammation.
Autorzy :
Raucci F; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131, Naples, Italy.
Iqbal AJ; Institute of Cardiovascular Sciences (ICVS), College of Medical and Dental Sciences, University of Birmingham, Birmingham, B15 2TT, UK.
Saviano A; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131, Naples, Italy.
Minosi P; National Center for Drug Research and Evaluation, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161, Rome, Italy.
Piccolo M; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131, Naples, Italy.
Irace C; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131, Naples, Italy.
Caso F; Rheumatology Unit, Department of Clinical Medicine and Surgery, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131, Naples, Italy.
Scarpa R; Rheumatology Unit, Department of Clinical Medicine and Surgery, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131, Naples, Italy.
Pieretti S; National Center for Drug Research and Evaluation, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161, Rome, Italy.
Mascolo N; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131, Naples, Italy.
Maione F; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131, Naples, Italy. Electronic address: .
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Źródło :
Pharmacological research [Pharmacol Res] 2019 Sep; Vol. 147, pp. 104351. Date of Electronic Publication: 2019 Jul 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Uric Acid*
Antibodies, Neutralizing/*immunology
Gout/*immunology
Interleukin-17/*immunology
Animals ; Edema/immunology ; Edema/pathology ; Gout/pathology ; Inflammation/immunology ; Inflammation/pathology ; Injections, Intra-Articular ; Knee Joint/immunology ; Knee Joint/pathology ; Male ; Mice
Czasopismo naukowe
Tytuł :
In-depth immunophenotyping data relating to IL-17Ab modulation of circulating Treg/Th17 cells and of in situ infiltrated inflammatory monocytes in the onset of gouty inflammation.
Autorzy :
Raucci F; ImmunoPharmaLab, Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131, Naples, Italy.
Iqbal AJ; Institute of Cardiovascular Sciences (ICVS), College of Medical and Dental Sciences, University of Birmingham, Birmingham, B15 2TT, UK.; ImmunoPharmaLab, Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131, Naples, Italy.
Saviano A; ImmunoPharmaLab, Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131, Naples, Italy.
Casillo GM; ImmunoPharmaLab, Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131, Naples, Italy.
Russo M; ImmunoPharmaLab, Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131, Naples, Italy.
Lezama D; Institute of Cardiovascular Sciences (ICVS), College of Medical and Dental Sciences, University of Birmingham, Birmingham, B15 2TT, UK.
Mascolo N; ImmunoPharmaLab, Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131, Naples, Italy.
Maione F; ImmunoPharmaLab, Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131, Naples, Italy.
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Źródło :
Data in brief [Data Brief] 2019 Aug 12; Vol. 25, pp. 104381. Date of Electronic Publication: 2019 Aug 12 (Print Publication: 2019).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Cannabinoid receptor 2 deficiency exacerbates inflammation and neutrophil recruitment.
Autorzy :
Kapellos TS; Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom.
Taylor L; Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom.
Feuerborn A; Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom.
Valaris S; Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom.
Hussain MT; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.
Rainger GE; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.
Greaves DR; Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom.
Iqbal AJ; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.
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Źródło :
FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2019 May; Vol. 33 (5), pp. 6154-6167. Date of Electronic Publication: 2019 Feb 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Movement*
Transcriptome*
Neutrophils/*immunology
Receptor, Cannabinoid, CB2/*deficiency
Animals ; Cell Adhesion ; Cells, Cultured ; Chemokine CCL2/genetics ; Chemokine CCL2/metabolism ; Chemokine CCL4/genetics ; Chemokine CCL4/metabolism ; Chemokine CXCL10/genetics ; Chemokine CXCL10/metabolism ; Female ; Humans ; Immunity, Innate ; Male ; Matrix Metalloproteinase 9/genetics ; Matrix Metalloproteinase 9/metabolism ; Mice ; Mice, Inbred C57BL ; Neutrophils/physiology ; Receptor, Cannabinoid, CB2/genetics
Czasopismo naukowe
Tytuł :
Nanobiologics: a real game changer for targeted immunotherapy.
Autorzy :
Iqbal AJ; The Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham, UK.
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Źródło :
Cardiovascular research [Cardiovasc Res] 2019 May 01; Vol. 115 (6), pp. e52-e53.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Comment
MeSH Terms :
Immunologic Factors*
Immunotherapy*
Humans ; Inflammation ; Myeloid Cells
Czasopismo naukowe
Tytuł :
Repetitive Exposure of IL-17 Into the Murine Air Pouch Favors the Recruitment of Inflammatory Monocytes and the Release of IL-16 and TREM-1 in the Inflammatory Fluids.
Autorzy :
Maione F; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Naples, Italy.; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.
Iqbal AJ; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.
Raucci F; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Naples, Italy.
Letek M; Health Science Research Centre, Department of Life Science, University of Roehampton, London, United Kingdom.
Bauer M; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.
D'Acquisto F; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.; Health Science Research Centre, Department of Life Science, University of Roehampton, London, United Kingdom.
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Źródło :
Frontiers in immunology [Front Immunol] 2018 Nov 30; Vol. 9, pp. 2752. Date of Electronic Publication: 2018 Nov 30 (Print Publication: 2018).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Interleukin-16/*immunology
Interleukin-17/*immunology
Monocytes/*immunology
Triggering Receptor Expressed on Myeloid Cells-1/*immunology
Animals ; Inflammation/immunology ; Inflammation/pathology ; Mice ; Monocytes/pathology ; Neutrophils/immunology ; Neutrophils/pathology
Czasopismo naukowe
Tytuł :
Signalling through Src family kinase isoforms is not redundant in models of thrombo-inflammatory vascular disease.
Autorzy :
Harrison MJ; Institute of Cardiovascular Sciences, College of Medical and Dental Science, The Medical School, University of Birmingham, Birmingham, UK.
Chimen M; Institute of Cardiovascular Sciences, College of Medical and Dental Science, The Medical School, University of Birmingham, Birmingham, UK.
Hussain M; Institute of Cardiovascular Sciences, College of Medical and Dental Science, The Medical School, University of Birmingham, Birmingham, UK.
Iqbal AJ; Institute of Cardiovascular Sciences, College of Medical and Dental Science, The Medical School, University of Birmingham, Birmingham, UK.
Senis YA; Institute of Cardiovascular Sciences, College of Medical and Dental Science, The Medical School, University of Birmingham, Birmingham, UK.
Nash GB; Institute of Cardiovascular Sciences, College of Medical and Dental Science, The Medical School, University of Birmingham, Birmingham, UK.
Watson SP; Institute of Cardiovascular Sciences, College of Medical and Dental Science, The Medical School, University of Birmingham, Birmingham, UK.
Rainger GE; Institute of Cardiovascular Sciences, College of Medical and Dental Science, The Medical School, University of Birmingham, Birmingham, UK.
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Źródło :
Journal of cellular and molecular medicine [J Cell Mol Med] 2018 Sep; Vol. 22 (9), pp. 4317-4327. Date of Electronic Publication: 2018 Jul 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Apolipoproteins E/*genetics
Coronary Artery Disease/*genetics
Monocytes/*metabolism
Proto-Oncogene Proteins/*genetics
src-Family Kinases/*genetics
Animals ; Aorta/metabolism ; Aorta/pathology ; Apolipoproteins E/deficiency ; Cell Adhesion ; Coronary Artery Disease/etiology ; Coronary Artery Disease/metabolism ; Coronary Artery Disease/pathology ; Diet, High-Fat/adverse effects ; Female ; Gene Expression Regulation ; Human Umbilical Vein Endothelial Cells/cytology ; Human Umbilical Vein Endothelial Cells/metabolism ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Monocytes/pathology ; Primary Cell Culture ; Proto-Oncogene Proteins/deficiency ; Signal Transduction ; src-Family Kinases/deficiency
Czasopismo naukowe
Tytuł :
The Role of Metabolite-Sensing G Protein-Coupled Receptors in Inflammation and Metabolic Disease.
Autorzy :
Recio C; 1 Sir William Dunn School of Pathology, University of Oxford , Oxford, Great Britain .
Lucy D; 2 Department of Chemistry, University of Oxford , Oxford, Great Britain .
Iveson P; 1 Sir William Dunn School of Pathology, University of Oxford , Oxford, Great Britain .
Iqbal AJ; 1 Sir William Dunn School of Pathology, University of Oxford , Oxford, Great Britain .
Valaris S; 1 Sir William Dunn School of Pathology, University of Oxford , Oxford, Great Britain .
Wynne G; 2 Department of Chemistry, University of Oxford , Oxford, Great Britain .
Russell AJ; 2 Department of Chemistry, University of Oxford , Oxford, Great Britain .
Choudhury RP; 3 Radcliffe Department of Medicine, University of Oxford , Oxford, Great Britain .
O'Callaghan C; 4 Nuffield Department of Medicine, University of Oxford , Oxford, Great Britain .
Monaco C; 5 Kennedy Institute for Rheumatology, University of Oxford , Oxford, Great Britain .
Greaves DR; 1 Sir William Dunn School of Pathology, University of Oxford , Oxford, Great Britain .
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Źródło :
Antioxidants & redox signaling [Antioxid Redox Signal] 2018 Jul 20; Vol. 29 (3), pp. 237-256. Date of Electronic Publication: 2018 Jan 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Inflammation/*metabolism
Metabolic Diseases/*metabolism
Receptors, G-Protein-Coupled/*metabolism
Animals ; Humans
Czasopismo naukowe
Tytuł :
Activation of the Immune-Metabolic Receptor GPR84 Enhances Inflammation and Phagocytosis in Macrophages.
Autorzy :
Recio C; Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom.
Lucy D; Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom.; Department of Chemistry, University of Oxford, Oxford, United Kingdom.
Purvis GSD; Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom.
Iveson P; Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom.
Zeboudj L; Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom.
Iqbal AJ; Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom.
Lin D; Nuffield Department of Medicine, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.
O'Callaghan C; Nuffield Department of Medicine, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.
Davison L; Nuffield Department of Medicine, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.
Griesbach E; Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom.
Russell AJ; Department of Chemistry, University of Oxford, Oxford, United Kingdom.; Department of Pharmacology, University of Oxford, Oxford, United Kingdom.
Wynne GM; Department of Chemistry, University of Oxford, Oxford, United Kingdom.
Dib L; Kennedy Institute of Rheumatology, University of Oxford, Oxford, United Kingdom.
Monaco C; Kennedy Institute of Rheumatology, University of Oxford, Oxford, United Kingdom.
Greaves DR; Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom.
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Źródło :
Frontiers in immunology [Front Immunol] 2018 Jun 20; Vol. 9, pp. 1419. Date of Electronic Publication: 2018 Jun 20 (Print Publication: 2018).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
A model for the optimization of anti-inflammatory treatment with chemerin.
Autorzy :
Laranjeira S; Department of Engineering Science, University of Oxford, Oxford, UK.
Regan-Komito D; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK.
Iqbal AJ; Sir William Dunn School of Pathology, University of Oxford, Oxford, UK.
Greaves DR; Sir William Dunn School of Pathology, University of Oxford, Oxford, UK.
Payne SJ; Department of Engineering Science, University of Oxford, Oxford, UK.
Orlowski P; Department of Engineering Science, University of Oxford, Oxford, UK.
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Źródło :
Interface focus [Interface Focus] 2018 Feb 06; Vol. 8 (1), pp. 20170007. Date of Electronic Publication: 2017 Dec 15.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
In Vitro Migration Assays.
Autorzy :
Taylor L; Sir William Dunn School of Pathology, University of Oxford, Oxford, UK.
Recio C; Sir William Dunn School of Pathology, University of Oxford, Oxford, UK.
Greaves DR; Sir William Dunn School of Pathology, University of Oxford, Oxford, UK.
Iqbal AJ; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK. A.J.Iqbal@bham.ac.uk.
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Źródło :
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2018; Vol. 1784, pp. 197-214.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Biological Assay/*methods
Cell Movement/*genetics
Chemotaxis/*genetics
Macrophages/*immunology
Adaptive Immunity/genetics ; Cell Movement/immunology ; Chemokines, CC/genetics ; Chemokines, CXC/genetics ; Chemotactic Factors/genetics ; Chemotaxis/immunology ; Humans ; Immunity, Innate/genetics ; Inflammation/immunology ; Inflammation/pathology ; Interleukin-1/genetics ; Macrophages/metabolism
Czasopismo naukowe

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