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Wyszukujesz frazę ""Ireland, Philip M."" wg kryterium: Autor


Wyświetlanie 1-9 z 9
Tytuł :
Global Analysis of Genes Essential for Francisella tularensis Schu S4 Growth In Vitro and for Fitness during Competitive Infection of Fischer 344 Rats.
Autorzy :
Ireland PM; Defence Science and Technology Laboratory, Chemical, Biological and Radiological Division, Salisbury, United Kingdom .
Bullifent HL; Defence Science and Technology Laboratory, Chemical, Biological and Radiological Division, Salisbury, United Kingdom.
Senior NJ; College of Life and Environmental Sciences, University of Exeter, Exeter, United Kingdom.
Southern SJ; Defence Science and Technology Laboratory, Chemical, Biological and Radiological Division, Salisbury, United Kingdom.
Yang ZR; College of Life and Environmental Sciences, University of Exeter, Exeter, United Kingdom.
Ireland RE; Defence Science and Technology Laboratory, Chemical, Biological and Radiological Division, Salisbury, United Kingdom.
Nelson M; Defence Science and Technology Laboratory, Chemical, Biological and Radiological Division, Salisbury, United Kingdom.
Atkins HS; Defence Science and Technology Laboratory, Chemical, Biological and Radiological Division, Salisbury, United Kingdom.; College of Life and Environmental Sciences, University of Exeter, Exeter, United Kingdom.; Department of Pathogen Molecular Biology, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Titball RW; College of Life and Environmental Sciences, University of Exeter, Exeter, United Kingdom.
Scott AE; Defence Science and Technology Laboratory, Chemical, Biological and Radiological Division, Salisbury, United Kingdom.
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Źródło :
Journal of bacteriology [J Bacteriol] 2019 Mar 13; Vol. 201 (7). Date of Electronic Publication: 2019 Mar 13 (Print Publication: 2019).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genes, Bacterial*
Francisella tularensis/*genetics
Francisella tularensis/*growth & development
Tularemia/*microbiology
Virulence Factors/*genetics
Animals ; DNA Mutational Analysis ; DNA Transposable Elements ; Disease Models, Animal ; Genetic Testing ; Mutagenesis, Insertional ; Neocallimastigales ; Rats, Inbred F344
Czasopismo naukowe
Tytuł :
Genome Resequencing of Laboratory Stocks of Burkholderia pseudomallei K96243.
Autorzy :
Wagley S; Biosciences, University of Exeter, Devon, United Kingdom.
Scott AE; Defence Science and Technology Laboratory, Salisbury, Wiltshire, United Kingdom.
Ireland PM; Defence Science and Technology Laboratory, Salisbury, Wiltshire, United Kingdom.
Prior JL; Defence Science and Technology Laboratory, Salisbury, Wiltshire, United Kingdom.
Atkins TP; Defence Science and Technology Laboratory, Salisbury, Wiltshire, United Kingdom.
Bancroft GJ; London School of Hygiene & Tropical Medicine, London, United Kingdom.
Studholme DJ; Biosciences, University of Exeter, Devon, United Kingdom.
Titball RW; Biosciences, University of Exeter, Devon, United Kingdom.
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Źródło :
Microbiology resource announcements [Microbiol Resour Announc] 2019 Feb 28; Vol. 8 (9). Date of Electronic Publication: 2019 Feb 28 (Print Publication: 2019).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Virulence of the Melioidosis Pathogen Burkholderia pseudomallei Requires the Oxidoreductase Membrane Protein DsbB.
Autorzy :
McMahon RM; Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland, Australia .; Griffith Institute for Drug Discovery, Griffith University, Nathan, Queensland, Australia.
Ireland PM; Defence Science and Technology Laboratory, Chemical, Biological and Radiological Division, Porton Down, Salisbury, Wiltshire, United Kingdom .
Sarovich DS; Global and Tropical Health Division, Menzies School of Health Research, Darwin, Northern Territory, Australia.; Faculty of Science, Health, Education and Engineering, University of the Sunshine Coast, Sippy Downs, Queensland, Australia.
Petit G; Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland, Australia.
Jenkins CH; Defence Science and Technology Laboratory, Chemical, Biological and Radiological Division, Porton Down, Salisbury, Wiltshire, United Kingdom.
Sarkar-Tyson M; Marshall Centre for Infectious Disease Research and Training, School of Pathology and Laboratory Medicine, University of Western Australia, Perth, Western Australia, Australia.
Currie BJ; Global and Tropical Health Division, Menzies School of Health Research, Darwin, Northern Territory, Australia.
Martin JL; Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland, Australia .; Griffith Institute for Drug Discovery, Griffith University, Nathan, Queensland, Australia.
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Źródło :
Infection and immunity [Infect Immun] 2018 Apr 23; Vol. 86 (5). Date of Electronic Publication: 2018 Apr 23 (Print Publication: 2018).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Burkholderia pseudomallei/*genetics
Burkholderia pseudomallei/*pathogenicity
Melioidosis/*pathology
Membrane Proteins/*immunology
Mice, Inbred BALB C/*immunology
Oxidoreductases/*immunology
Virulence/*genetics
Animals ; Australia ; Burkholderia pseudomallei/immunology ; Disease Models, Animal ; Melioidosis/genetics ; Melioidosis/microbiology ; Membrane Proteins/genetics ; Membrane Proteins/metabolism ; Mice ; Oxidoreductases/genetics ; Oxidoreductases/metabolism ; Virulence/immunology
Czasopismo naukowe
Tytuł :
An integrated computational-experimental approach reveals Yersinia pestis genes essential across a narrow or a broad range of environmental conditions.
Autorzy :
Senior NJ; College of Life and Environmental Sciences, University of Exeter, Exeter, EX4 4SB, UK.
Sasidharan K; School of Life Sciences, University of Warwick, Coventry, CV4 7AL, UK.
Saint RJ; Defence Science Technology Laboratory, Porton Down, Salisbury, SP4 OJQ, UK.
Scott AE; Defence Science Technology Laboratory, Porton Down, Salisbury, SP4 OJQ, UK.
Sarkar-Tyson M; Defence Science Technology Laboratory, Porton Down, Salisbury, SP4 OJQ, UK.; Marshall Centre for Infectious Disease Research and Training, School of Pathology and Laboratory Medicine, University of Western Australia, Perth, WA, 6009, Australia.
Ireland PM; Defence Science Technology Laboratory, Porton Down, Salisbury, SP4 OJQ, UK.
Bullifent HL; Defence Science Technology Laboratory, Porton Down, Salisbury, SP4 OJQ, UK.
Rong Yang Z; College of Life and Environmental Sciences, University of Exeter, Exeter, EX4 4SB, UK.
Moore K; College of Life and Environmental Sciences, University of Exeter, Exeter, EX4 4SB, UK.
Oyston PCF; Defence Science Technology Laboratory, Porton Down, Salisbury, SP4 OJQ, UK.
Atkins TP; College of Life and Environmental Sciences, University of Exeter, Exeter, EX4 4SB, UK.; Defence Science Technology Laboratory, Porton Down, Salisbury, SP4 OJQ, UK.
Atkins HS; College of Life and Environmental Sciences, University of Exeter, Exeter, EX4 4SB, UK.; Defence Science Technology Laboratory, Porton Down, Salisbury, SP4 OJQ, UK.
Soyer OS; School of Life Sciences, University of Warwick, Coventry, CV4 7AL, UK.
Titball RW; College of Life and Environmental Sciences, University of Exeter, Exeter, EX4 4SB, UK. .
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Źródło :
BMC microbiology [BMC Microbiol] 2017 Jul 21; Vol. 17 (1), pp. 163. Date of Electronic Publication: 2017 Jul 21.
Typ publikacji :
Evaluation Study; Journal Article
MeSH Terms :
Genes, Essential*
Bacterial Proteins/*genetics
Computational Biology/*methods
Plague/*microbiology
Yersinia pestis/*genetics
Bacterial Proteins/metabolism ; Gene Expression Regulation, Bacterial ; Humans ; Mutation ; Yersinia pestis/growth & development ; Yersinia pestis/metabolism
Czasopismo naukowe
Tytuł :
Trehalase plays a role in macrophage colonization and virulence of Burkholderia pseudomallei in insect and mammalian hosts.
Autorzy :
Vanaporn M; a College of Life and Environmental Sciences, University of Exeter , Exeter , UK.; b Department of Microbiology and Immunology , Faculty of Tropical Medicine, Mahidol University , Bangkok , Thailand.
Sarkar-Tyson M; c CBR Division, Defense Science and Technology Laboratory , Salisbury , UK.
Kovacs-Simon A; a College of Life and Environmental Sciences, University of Exeter , Exeter , UK.
Ireland PM; c CBR Division, Defense Science and Technology Laboratory , Salisbury , UK.
Pumirat P; b Department of Microbiology and Immunology , Faculty of Tropical Medicine, Mahidol University , Bangkok , Thailand.
Korbsrisate S; d Department of Immunology, Faculty of Medicine , Siriraj Hospital, Mahidol University , Bangkok , Thailand.
Titball RW; a College of Life and Environmental Sciences, University of Exeter , Exeter , UK.
Butt A; a College of Life and Environmental Sciences, University of Exeter , Exeter , UK.
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Źródło :
Virulence [Virulence] 2017 Jan 02; Vol. 8 (1), pp. 30-40. Date of Electronic Publication: 2016 Jul 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Burkholderia pseudomallei/*enzymology
Burkholderia pseudomallei/*pathogenicity
Macrophages/*microbiology
Melioidosis/*microbiology
Moths/*microbiology
Trehalase/*metabolism
Animals ; Biofilms/growth & development ; Burkholderia pseudomallei/genetics ; Burkholderia pseudomallei/growth & development ; Disease Models, Animal ; Larva/microbiology ; Mice ; Sequence Deletion ; Stress, Physiological ; Temperature ; Trehalase/genetics ; Trehalose/metabolism ; Virulence ; Virulence Factors/genetics
Czasopismo naukowe
Tytuł :
Survival protein A is essential for virulence in Yersinia pestis.
Autorzy :
Southern SJ; Defence Science and Technology Laboratory, Biomedical Sciences, Porton Down, Salisbury, Wiltshire, SP4 0JQ, UK. Electronic address: .
Scott AE; Defence Science and Technology Laboratory, Biomedical Sciences, Porton Down, Salisbury, Wiltshire, SP4 0JQ, UK.
Jenner DC; Defence Science and Technology Laboratory, Biomedical Sciences, Porton Down, Salisbury, Wiltshire, SP4 0JQ, UK.
Ireland PM; Defence Science and Technology Laboratory, Biomedical Sciences, Porton Down, Salisbury, Wiltshire, SP4 0JQ, UK.
Norville IH; Defence Science and Technology Laboratory, Biomedical Sciences, Porton Down, Salisbury, Wiltshire, SP4 0JQ, UK.
Sarkar-Tyson M; Defence Science and Technology Laboratory, Biomedical Sciences, Porton Down, Salisbury, Wiltshire, SP4 0JQ, UK; University of Western Australia, QEII Medical Centre, Nedlands, WA, Australia.
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Źródło :
Microbial pathogenesis [Microb Pathog] 2016 Mar; Vol. 92, pp. 50-53. Date of Electronic Publication: 2015 Dec 25.
Typ publikacji :
Journal Article
MeSH Terms :
Bacterial Proteins/*genetics
Plague/*microbiology
Yersinia pestis/*pathogenicity
Yersinia pestis/*physiology
Animals ; Bacterial Proteins/metabolism ; Disease Models, Animal ; Female ; Gene Deletion ; Genetic Complementation Test ; Mice ; Plague/mortality ; Virulence/genetics ; Virulence Factors
Czasopismo naukowe
Tytuł :
Disarming Burkholderia pseudomallei: structural and functional characterization of a disulfide oxidoreductase (DsbA) required for virulence in vivo.
Autorzy :
Ireland PM; 1 Defence Science and Technology Laboratory , Porton Down, Salisbury, Wiltshire, United Kingdom .
McMahon RM
Marshall LE
Halili M
Furlong E
Tay S
Martin JL
Sarkar-Tyson M
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Źródło :
Antioxidants & redox signaling [Antioxid Redox Signal] 2014 Feb 01; Vol. 20 (4), pp. 606-17. Date of Electronic Publication: 2013 Sep 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Bacterial Proteins/*chemistry
Burkholderia pseudomallei/*enzymology
Protein Disulfide Reductase (Glutathione)/*chemistry
Animals ; Bacterial Proteins/metabolism ; Burkholderia pseudomallei/pathogenicity ; Catalytic Domain ; Cell Line ; Crystallography, X-Ray ; Female ; Mice ; Mice, Inbred BALB C ; Models, Molecular ; Oxidation-Reduction ; Peptide Hydrolases/metabolism ; Protein Disulfide Reductase (Glutathione)/metabolism ; Protein Structure, Secondary ; Type C Phospholipases/metabolism ; Virulence
Czasopismo naukowe
Tytuł :
The serine protease inhibitor Ecotin is required for full virulence of Burkholderia pseudomallei.
Autorzy :
Ireland PM; Defence Science and Technology Laboratory, Porton Down, Salisbury, Wiltshire SP4 0JQ, UK. Electronic address: .
Marshall L; Defence Science and Technology Laboratory, Porton Down, Salisbury, Wiltshire SP4 0JQ, UK.
Norville I; Defence Science and Technology Laboratory, Porton Down, Salisbury, Wiltshire SP4 0JQ, UK.
Sarkar-Tyson M; Defence Science and Technology Laboratory, Porton Down, Salisbury, Wiltshire SP4 0JQ, UK; Pathology & Laboratory Medicine M504, University of Western Australia, 35 Stirling Hwy, Crawley, WA 6009, Australia.
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Źródło :
Microbial pathogenesis [Microb Pathog] 2014 Feb-Mar; Vol. 67-68, pp. 55-8. Date of Electronic Publication: 2014 Jan 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Bacterial Proteins/*metabolism
Burkholderia pseudomallei/*metabolism
Burkholderia pseudomallei/*pathogenicity
Melioidosis/*microbiology
Serine Proteinase Inhibitors/*metabolism
Animals ; Bacterial Proteins/genetics ; Burkholderia pseudomallei/genetics ; Female ; Humans ; Macrophages/immunology ; Macrophages/microbiology ; Melioidosis/immunology ; Mice ; Mice, Inbred BALB C ; Serine Proteinase Inhibitors/genetics ; Virulence
Czasopismo naukowe
Tytuł :
A Francisella tularensis SCHU S4 mutant deficient in γ-glutamyltransferase activity induces protective immunity: characterization of an attenuated vaccine candidate.
Autorzy :
Ireland PM; Defence Science and Technology Laboratory, Porton Down, Salisbury, Wiltshire SP4 0JQ, UK.
LeButt H; Defence Science and Technology Laboratory, Porton Down, Salisbury, Wiltshire SP4 0JQ, UK.
Thomas RM; Defence Science and Technology Laboratory, Porton Down, Salisbury, Wiltshire SP4 0JQ, UK.
Oyston PCF; Defence Science and Technology Laboratory, Porton Down, Salisbury, Wiltshire SP4 0JQ, UK.
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Źródło :
Microbiology (Reading, England) [Microbiology (Reading)] 2011 Nov; Vol. 157 (Pt 11), pp. 3172-3179. Date of Electronic Publication: 2011 Aug 18.
Typ publikacji :
Journal Article
MeSH Terms :
Bacterial Vaccines/*immunology
Francisella tularensis/*pathogenicity
Tularemia/*immunology
gamma-Glutamyltransferase/*genetics
Animals ; Bacterial Vaccines/genetics ; Cell Line ; Female ; Francisella tularensis/enzymology ; Francisella tularensis/genetics ; Genetic Complementation Test ; Macrophages/immunology ; Macrophages/microbiology ; Mice ; Mice, Inbred BALB C ; Sequence Deletion ; Tularemia/prevention & control ; Vaccines, Attenuated/genetics ; Vaccines, Attenuated/immunology ; Virulence
Czasopismo naukowe
    Wyświetlanie 1-9 z 9

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