Temat: "Iron regulatory protein" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: KLF14 regulates the growth of hepatocellular carcinoma cells via its modulation of iron homeostasis through the repression of iron-responsive element-binding protein 2.
Autorzy:: Zhou H; College of Life Science, Zhejiang University, Hangzhou, 310058, Zhejiang, China.
Chen J; Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310003, Zhejiang, China.
Fan M; College of Life Science, Zhejiang University, Hangzhou, 310058, Zhejiang, China.; Department of Pediatrics, The First Affiliated Hospital, School of Medicine Zhejiang University, Hangzhou, 310003, Zhejiang, China.
Cai H; College of Life Science, Zhejiang University, Hangzhou, 310058, Zhejiang, China.
Dong Y; College of Life Science, Zhejiang University, Hangzhou, 310058, Zhejiang, China.
Qiu Y; College of Life Science, Zhejiang University, Hangzhou, 310058, Zhejiang, China.
Zhuang Q; College of Life Science, Zhejiang University, Hangzhou, 310058, Zhejiang, China.
Lei Z; College of Life Science, Zhejiang University, Hangzhou, 310058, Zhejiang, China.
Li M; College of Life Science, Zhejiang University, Hangzhou, 310058, Zhejiang, China.
Ding X; College of Life Science, Zhejiang University, Hangzhou, 310058, Zhejiang, China.
Yan P; College of Life Science, Zhejiang University, Hangzhou, 310058, Zhejiang, China.
Lin A; College of Life Science, Zhejiang University, Hangzhou, 310058, Zhejiang, China.
Zheng S; Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310003, Zhejiang, China. .
Yan Q; College of Life Science, Zhejiang University, Hangzhou, 310058, Zhejiang, China. .; Department of Pediatrics, The First Affiliated Hospital, School of Medicine Zhejiang University, Hangzhou, 310003, Zhejiang, China. .; Key Laboratory for Cell and Gene Engineering of Zhejiang Province, Hangzhou, 310058, Zhejiang, China. .; Pokaż więcej
Źródło:: Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2023 Jan 05; Vol. 42 (1), pp. 5. Date of Electronic Publication: 2023 Jan 05.
Typ publikacji:: Journal Article
MeSH Terms:: Carcinoma, Hepatocellular*/drug therapy
Carcinoma, Hepatocellular*/genetics
Carcinoma, Hepatocellular*/metabolism
Iron*/metabolism
Iron Regulatory Protein 2*/genetics
Iron Regulatory Protein 2*/metabolism
Kruppel-Like Transcription Factors*/genetics
Kruppel-Like Transcription Factors*/metabolism
Animals ; Humans ; Mice ; Cell Line, Tumor ; Cell Proliferation ; Fluphenazine ; Gene Expression Regulation, Neoplastic ; Homeostasis ; Liver Neoplasms/drug therapy ; Liver Neoplasms/genetics ; Liver Neoplasms/metabolism

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 2.

Tytuł:: A novel treatment strategy to prevent Parkinson's disease: focus on iron regulatory protein 1 (IRP1).
Autorzy:: Berry TM; School of Psychology, Western Sydney University, Sydney, New South Wales, Australia.
Moustafa AA; School of Psychology, Western Sydney University, Sydney, New South Wales, Australia.; Marcs Institute for Brain and Behaviour, Western Sydney University, Sydney, New South Wales, Australia.; Department of Human Anatomy and Physiology, the Faculty of Health Sciences, University of Johannesburg, Johannesburg, South Africa.; Pokaż więcej
Źródło:: The International journal of neuroscience [Int J Neurosci] 2023 Jan; Vol. 133 (1), pp. 67-76. Date of Electronic Publication: 2021 May 04.
Typ publikacji:: Journal Article
MeSH Terms:: Iron Regulatory Protein 1*/metabolism
Parkinson Disease*/etiology
Parkinson Disease*/prevention & control
Rats ; Animals ; Rotenone ; Aconitate Hydratase/metabolism ; Iron/metabolism ; Sulfur/metabolism

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 3.

Tytuł:: β-catenin-IRP2-primed iron availability to mitochondrial metabolism is druggable for active β-catenin-mediated cancer.
Autorzy:: Wu Y; State Key Laboratory of Medical Molecular Biology, Haihe Laboratory of Cell Ecosystem, Department of Physiology, Institute of Basic Medical Sciences and School of Basic Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, 5 Dong Dan San Tiao, Beijing, China.
Yang S; State Key Laboratory of Medical Molecular Biology, Haihe Laboratory of Cell Ecosystem, Department of Physiology, Institute of Basic Medical Sciences and School of Basic Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, 5 Dong Dan San Tiao, Beijing, China.
Han L; State Key Laboratory of Medical Molecular Biology, Haihe Laboratory of Cell Ecosystem, Department of Physiology, Institute of Basic Medical Sciences and School of Basic Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, 5 Dong Dan San Tiao, Beijing, China.
Shang K; State Key Laboratory of Medical Molecular Biology, Haihe Laboratory of Cell Ecosystem, Department of Physiology, Institute of Basic Medical Sciences and School of Basic Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, 5 Dong Dan San Tiao, Beijing, China.
Zhang B; Department of Physiology, School of Life Science, China Medical University, Shenyang, China.
Gai X; State Key Laboratory of Medical Molecular Biology, Haihe Laboratory of Cell Ecosystem, Department of Physiology, Institute of Basic Medical Sciences and School of Basic Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, 5 Dong Dan San Tiao, Beijing, China.
Deng W; State Key Laboratory of Medical Molecular Biology, Haihe Laboratory of Cell Ecosystem, Department of Physiology, Institute of Basic Medical Sciences and School of Basic Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, 5 Dong Dan San Tiao, Beijing, China.
Liu F; State Key Laboratory of Medical Molecular Biology, Haihe Laboratory of Cell Ecosystem, Department of Physiology, Institute of Basic Medical Sciences and School of Basic Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, 5 Dong Dan San Tiao, Beijing, China. .
Zhang H; State Key Laboratory of Medical Molecular Biology, Haihe Laboratory of Cell Ecosystem, Department of Physiology, Institute of Basic Medical Sciences and School of Basic Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, 5 Dong Dan San Tiao, Beijing, China. .; Pokaż więcej
Źródło:: Journal of translational medicine [J Transl Med] 2023 Jan 26; Vol. 21 (1), pp. 50. Date of Electronic Publication: 2023 Jan 26.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Iron Regulatory Protein 2*/metabolism
Neoplasms*/drug therapy
Mice ; Humans ; Animals ; beta Catenin/metabolism ; Iron/metabolism ; Iron Chelating Agents/pharmacology ; Mitochondria/metabolism

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 4.

Tytuł:: 6-Hydroxydopamine Induces Abnormal Iron Sequestration in BV2 Microglia by Activating Iron Regulatory Protein 1 and Inhibiting Hepcidin Release.
Autorzy:: Xu M; School of Basic Medicine, Qingdao University, Qingdao 266071, China.; Institute of Brain Science and Disease, Shandong Provincial Key Laboratory of Pathogenesis and Prevention of Neurological Disorders, Qingdao University, Qingdao 266071, China.; Medical Service Section, The Affiliated Hospital of Qingdao University, Qingdao 266071, China.
Li Y; School of Basic Medicine, Qingdao University, Qingdao 266071, China.; Institute of Brain Science and Disease, Shandong Provincial Key Laboratory of Pathogenesis and Prevention of Neurological Disorders, Qingdao University, Qingdao 266071, China.
Meng D; School of Basic Medicine, Qingdao University, Qingdao 266071, China.; Institute of Brain Science and Disease, Shandong Provincial Key Laboratory of Pathogenesis and Prevention of Neurological Disorders, Qingdao University, Qingdao 266071, China.
Zhang D; School of Basic Medicine, Qingdao University, Qingdao 266071, China.; Institute of Brain Science and Disease, Shandong Provincial Key Laboratory of Pathogenesis and Prevention of Neurological Disorders, Qingdao University, Qingdao 266071, China.
Wang B; School of Basic Medicine, Qingdao University, Qingdao 266071, China.; Institute of Brain Science and Disease, Shandong Provincial Key Laboratory of Pathogenesis and Prevention of Neurological Disorders, Qingdao University, Qingdao 266071, China.
Xie J; Institute of Brain Science and Disease, Shandong Provincial Key Laboratory of Pathogenesis and Prevention of Neurological Disorders, Qingdao University, Qingdao 266071, China.
Wang J; School of Basic Medicine, Qingdao University, Qingdao 266071, China.; Institute of Brain Science and Disease, Shandong Provincial Key Laboratory of Pathogenesis and Prevention of Neurological Disorders, Qingdao University, Qingdao 266071, China.; Pokaż więcej
Źródło:: Biomolecules [Biomolecules] 2022 Feb 07; Vol. 12 (2). Date of Electronic Publication: 2022 Feb 07.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Hepcidins*/genetics
Hepcidins*/metabolism
Iron Regulatory Protein 1*/genetics
Iron Regulatory Protein 1*/metabolism
Iron/metabolism ; Microglia/metabolism ; Oxidopamine/metabolism ; Oxidopamine/pharmacology

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 5.

Tytuł:: Iron response elements (IREs)-mRNA of Alzheimer's amyloid precursor protein binding to iron regulatory protein (IRP1): a combined molecular docking and spectroscopic approach.
Autorzy:: Khan MA; Department of Life Sciences, College of Science & General Studies, Alfaisal University, Riyadh, Saudi Arabia. .
Mohammad T; Centre for Interdisciplinary Research in Basic Sciences, Jamia Millia Islamia, Jamia Nagar, New Delhi, 110025, India.
Malik A; Department of Biochemistry, Protein Research Laboratory, College of Science, King Saud University, Riyadh, Saudi Arabia.
Hassan MI; Centre for Interdisciplinary Research in Basic Sciences, Jamia Millia Islamia, Jamia Nagar, New Delhi, 110025, India.
Domashevskiy AV; Department of Sciences, John Jay College of Criminal Justice, The City University of New York, New York, NY, 10019, USA.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2023 Mar 28; Vol. 13 (1), pp. 5073. Date of Electronic Publication: 2023 Mar 28.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Alzheimer Disease*/metabolism
Iron*/metabolism
Humans ; Amyloid beta-Protein Precursor/genetics ; Amyloid beta-Protein Precursor/metabolism ; Iron Regulatory Protein 1/metabolism ; Iron Regulatory Protein 2/genetics ; Iron-Regulatory Proteins/genetics ; Molecular Docking Simulation ; Protein Binding ; Response Elements ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Spectrum Analysis

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 6.

Tytuł:: Optimization of Biotinylated RNA or DNA Pull-Down Assays for Detection of Binding Proteins: Examples of IRP1, IRP2, HuR, AUF1, and Nrf2.
Autorzy:: Tsuji Y; Toxicology Program, Department of Biological Sciences, North Carolina State University, Campus Box 7633, Raleigh, NC 27695, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Feb 10; Vol. 24 (4). Date of Electronic Publication: 2023 Feb 10.
Typ publikacji:: Journal Article
MeSH Terms:: Carrier Proteins*/chemistry
DNA*/chemistry
RNA*/chemistry
Biotinylation*
Chromatography, Affinity*/methods
Humans ; Iron/metabolism ; Iron Regulatory Protein 1/chemistry ; Iron Regulatory Protein 2/chemistry ; NF-E2-Related Factor 2/chemistry ; Streptavidin/metabolism

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 7.

Tytuł:: Predicted loss and gain of function mutations in ACO1 are associated with erythropoiesis.
Autorzy:: Oskarsson GR; deCODE genetics/Amgen Inc., Reykjavik, Iceland.; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland.
Oddsson A; deCODE genetics/Amgen Inc., Reykjavik, Iceland.
Magnusson MK; deCODE genetics/Amgen Inc., Reykjavik, Iceland.; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland.
Kristjansson RP; deCODE genetics/Amgen Inc., Reykjavik, Iceland.
Halldorsson GH; deCODE genetics/Amgen Inc., Reykjavik, Iceland.
Ferkingstad E; deCODE genetics/Amgen Inc., Reykjavik, Iceland.
Zink F; deCODE genetics/Amgen Inc., Reykjavik, Iceland.
Helgadottir A; deCODE genetics/Amgen Inc., Reykjavik, Iceland.
Ivarsdottir EV; deCODE genetics/Amgen Inc., Reykjavik, Iceland.
Arnadottir GA; deCODE genetics/Amgen Inc., Reykjavik, Iceland.
Jensson BO; deCODE genetics/Amgen Inc., Reykjavik, Iceland.
Katrinardottir H; deCODE genetics/Amgen Inc., Reykjavik, Iceland.
Sveinbjornsson G; deCODE genetics/Amgen Inc., Reykjavik, Iceland.
Kristinsdottir AM; deCODE genetics/Amgen Inc., Reykjavik, Iceland.
Lee AL; deCODE genetics/Amgen Inc., Reykjavik, Iceland.
Saemundsdottir J; deCODE genetics/Amgen Inc., Reykjavik, Iceland.
Stefansdottir L; deCODE genetics/Amgen Inc., Reykjavik, Iceland.
Sigurdsson JK; deCODE genetics/Amgen Inc., Reykjavik, Iceland.
Davidsson OB; deCODE genetics/Amgen Inc., Reykjavik, Iceland.
Benonisdottir S; deCODE genetics/Amgen Inc., Reykjavik, Iceland.
Jonasdottir A; deCODE genetics/Amgen Inc., Reykjavik, Iceland.
Jonasdottir A; deCODE genetics/Amgen Inc., Reykjavik, Iceland.
Jonsson S; deCODE genetics/Amgen Inc., Reykjavik, Iceland.
Gudmundsson RL; deCODE genetics/Amgen Inc., Reykjavik, Iceland.
Asselbergs FW; Department of Cardiology, Division Heart & Lungs, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.; Institute of Cardiovascular Science, Faculty of Population Health Sciences, University College London, London, UK.; Health Data Research UK and Institute of Health Informatics, University College London, London, UK.
Tragante V; deCODE genetics/Amgen Inc., Reykjavik, Iceland.; Department of Cardiology, Division Heart & Lungs, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Gunnarsson B; deCODE genetics/Amgen Inc., Reykjavik, Iceland.
Masson G; deCODE genetics/Amgen Inc., Reykjavik, Iceland.
Thorleifsson G; deCODE genetics/Amgen Inc., Reykjavik, Iceland.
Rafnar T; deCODE genetics/Amgen Inc., Reykjavik, Iceland.
Holm H; deCODE genetics/Amgen Inc., Reykjavik, Iceland.
Olafsson I; Department of Clinical Biochemistry, Landspitali, the National University Hospital of Iceland, Reykjavik, Iceland.
Onundarson PT; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland.; Department of Laboratory Hematology, Landspitali, the National University Hospital of Iceland, Reykjavik, Iceland.
Gudbjartsson DF; deCODE genetics/Amgen Inc., Reykjavik, Iceland.; School of Engineering and Natural Sciences, University of Iceland, Reykjavik, Iceland.
Norddahl GL; deCODE genetics/Amgen Inc., Reykjavik, Iceland.
Thorsteinsdottir U; deCODE genetics/Amgen Inc., Reykjavik, Iceland.; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland.
Sulem P; deCODE genetics/Amgen Inc., Reykjavik, Iceland. .
Stefansson K; deCODE genetics/Amgen Inc., Reykjavik, Iceland. .; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland. .; Pokaż więcej
Źródło:: Communications biology [Commun Biol] 2020 Apr 23; Vol. 3 (1), pp. 189. Date of Electronic Publication: 2020 Apr 23.
Typ publikacji:: Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't
MeSH Terms:: Gain of Function Mutation*
Loss of Function Mutation*
Erythropoiesis/*genetics
Hemoglobins/*metabolism
Iron Regulatory Protein 1/*genetics
Biomarkers/blood ; Databases, Genetic ; Genome-Wide Association Study ; Humans ; Iceland ; Iron Regulatory Protein 1/metabolism ; United Kingdom

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 8.

Tytuł:: Aberrant Transferrin and Ferritin Upregulation Elicits Iron Accumulation and Oxidative Inflammaging Causing Ferroptosis and Undermines Estradiol Biosynthesis in Aging Rat Ovaries by Upregulating NF-Κb-Activated Inducible Nitric Oxide Synthase: First Demonstration of an Intricate Mechanism.
Autorzy:: Sze SCW; Department of Biology, Faculty of Science, Hong Kong Baptist University, Kowloon, Hong Kong SAR 999077, China.; Golden Meditech Center for NeuroRegeneration Sciences, Hong Kong Baptist University, Kowloon, Hong Kong SAR 999077, China.
Zhang L; School of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR 999077, China.
Zhang S; Department of Biology, Faculty of Science, Hong Kong Baptist University, Kowloon, Hong Kong SAR 999077, China.; Golden Meditech Center for NeuroRegeneration Sciences, Hong Kong Baptist University, Kowloon, Hong Kong SAR 999077, China.; JNU-HKUST Joint Laboratory for Neuroscience and Innovative Drug Research, College of Pharmacy, Jinan University, Guangzhou 999077, China.
Lin K; Department of Biology, Faculty of Science, Hong Kong Baptist University, Kowloon, Hong Kong SAR 999077, China.; Golden Meditech Center for NeuroRegeneration Sciences, Hong Kong Baptist University, Kowloon, Hong Kong SAR 999077, China.; School of Public Health, Guangzhou Medical University, Guangzhou 999077, China.
Ng TB; School of Life Sciences, Faculty of Science, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong SAR 999077, China.
Ng ML; Department of Biology, Faculty of Science, Hong Kong Baptist University, Kowloon, Hong Kong SAR 999077, China.; Golden Meditech Center for NeuroRegeneration Sciences, Hong Kong Baptist University, Kowloon, Hong Kong SAR 999077, China.
Lee KF; Department of Obstetrics and Gynaecology, LKS Faculty of Medicine, HKU, Pokfulam, Hong Kong SAR 999077, China.
Lam JKW; Department of Pharmaceutics, UCL School of Pharmacy, University College London, 29-39 Brunswick Square, London WC1N 1AX, UK.; Department of Pharmacology & Pharmacy, LKS Faculty of Medicine, HKU, Pokfulam, Hong Kong SAR 999077, China.
Zhang Z; Department of Biology, Faculty of Science, Hong Kong Baptist University, Kowloon, Hong Kong SAR 999077, China.; Golden Meditech Center for NeuroRegeneration Sciences, Hong Kong Baptist University, Kowloon, Hong Kong SAR 999077, China.
Yung KKL; Department of Biology, Faculty of Science, Hong Kong Baptist University, Kowloon, Hong Kong SAR 999077, China.; Golden Meditech Center for NeuroRegeneration Sciences, Hong Kong Baptist University, Kowloon, Hong Kong SAR 999077, China.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2022 Oct 21; Vol. 23 (20). Date of Electronic Publication: 2022 Oct 21.
Typ publikacji:: Journal Article
MeSH Terms:: NF-kappa B*/metabolism
Ferroptosis*
Rats ; Animals ; Female ; Nitric Oxide Synthase Type II/genetics ; Nitric Oxide Synthase Type II/metabolism ; NF-E2-Related Factor 2/metabolism ; Tumor Necrosis Factor-alpha/metabolism ; Kelch-Like ECH-Associated Protein 1/metabolism ; Ferritins/metabolism ; Up-Regulation ; Nitrites/metabolism ; Transferrin/metabolism ; Estradiol/metabolism ; Nitrates/metabolism ; Ovary/metabolism ; Apoferritins/metabolism ; Iron Regulatory Protein 2/metabolism ; Phospholipid Hydroperoxide Glutathione Peroxidase ; Aging ; Oxidative Stress ; Iron/metabolism ; Receptors, Transferrin/metabolism

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 9.

Tytuł:: Human IRP1 Translocates to the Nucleus in a Cell-Specific and Iron-Dependent Manner.
Autorzy:: Gu W; Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, QC H3T 1E2, Canada.
Fillebeen C; Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, QC H3T 1E2, Canada.
Pantopoulos K; Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, QC H3T 1E2, Canada.; Department of Medicine, McGill University, Montreal, QC H4A 3J1, Canada.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2022 Sep 15; Vol. 23 (18). Date of Electronic Publication: 2022 Sep 15.
Typ publikacji:: Journal Article
MeSH Terms:: Iron*/metabolism
Iron Regulatory Protein 1/*metabolism
Animals ; Fibroblasts/metabolism ; Humans ; Iron Chelating Agents ; Mammals/metabolism ; Mice ; RNA/metabolism

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 10.

Tytuł:: Iron Regulatory Protein 1 Inhibits Ferritin Translation Responding to OsHV-1 Infection in Ark Clams, Scapharca Broughtonii .
Autorzy:: Huang B; Qingdao Key Laboratory of Mariculture Epidemiology and Biosecurity, Key Laboratory of Maricultural Organism Disease Control, Ministry of Agriculture, Yellow Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Qingdao 266071, China.; Function Laboratory for Marine Fisheries Science and Food Production Processes, Qingdao National Laboratory for Marine Science and Technology, Qingdao 266071, China.
Zhang X; Qingdao Key Laboratory of Mariculture Epidemiology and Biosecurity, Key Laboratory of Maricultural Organism Disease Control, Ministry of Agriculture, Yellow Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Qingdao 266071, China.; Function Laboratory for Marine Fisheries Science and Food Production Processes, Qingdao National Laboratory for Marine Science and Technology, Qingdao 266071, China.
Liu Q; Guangxi Key Laboratory for Agricultural Resources Chemistry and Biotechnology, College of Biology and Pharmacy, Yulin Normal University, Yulin 537000, China.
Bai C; Qingdao Key Laboratory of Mariculture Epidemiology and Biosecurity, Key Laboratory of Maricultural Organism Disease Control, Ministry of Agriculture, Yellow Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Qingdao 266071, China.; Function Laboratory for Marine Fisheries Science and Food Production Processes, Qingdao National Laboratory for Marine Science and Technology, Qingdao 266071, China.
Li C; Qingdao Key Laboratory of Mariculture Epidemiology and Biosecurity, Key Laboratory of Maricultural Organism Disease Control, Ministry of Agriculture, Yellow Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Qingdao 266071, China.; Function Laboratory for Marine Fisheries Science and Food Production Processes, Qingdao National Laboratory for Marine Science and Technology, Qingdao 266071, China.
Wang C; Qingdao Key Laboratory of Mariculture Epidemiology and Biosecurity, Key Laboratory of Maricultural Organism Disease Control, Ministry of Agriculture, Yellow Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Qingdao 266071, China.; Function Laboratory for Marine Fisheries Science and Food Production Processes, Qingdao National Laboratory for Marine Science and Technology, Qingdao 266071, China.
Xin L; Qingdao Key Laboratory of Mariculture Epidemiology and Biosecurity, Key Laboratory of Maricultural Organism Disease Control, Ministry of Agriculture, Yellow Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Qingdao 266071, China.; Function Laboratory for Marine Fisheries Science and Food Production Processes, Qingdao National Laboratory for Marine Science and Technology, Qingdao 266071, China.; Pokaż więcej
Źródło:: Cells [Cells] 2022 Mar 13; Vol. 11 (6). Date of Electronic Publication: 2022 Mar 13.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Scapharca*/genetics
Animals ; Ferritins/genetics ; Ferritins/metabolism ; Iron/metabolism ; Iron Regulatory Protein 1/metabolism ; RNA, Messenger/genetics

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 11.

Tytuł:: Decreased cerebral Irp-1B limits impact of social isolation in wild type and Alzheimer's disease modeled in Drosophila melanogaster.
Autorzy:: Ruland C; Institute of Neuropathology, University Hospital Münster, Münster, Germany.; Department of Psychiatry, University of Münster, Münster, Germany.
Berlandi J; Institute of Neuropathology, University Hospital Münster, Münster, Germany.
Eikmeier K; Institute of Neuropathology, University Hospital Münster, Münster, Germany.
Weinert T; Institute of Neuropathology, University Hospital Münster, Münster, Germany.
Lin FJ; Department of Biology, Coastal Carolina University, Conway, South Carolina.
Ambree O; Department of Psychiatry, University of Münster, Münster, Germany.; Department of Behavioral Biology, University of Osnabrück, Osnabrück, Germany.
Seggewiss J; Institute for Human Genetics, University Hospital Münster, Münster, Germany.
Paulus W; Institute of Neuropathology, University Hospital Münster, Münster, Germany.
Jeibmann A; Institute of Neuropathology, University Hospital Münster, Münster, Germany.; Pokaż więcej
Źródło:: Genes, brain, and behavior [Genes Brain Behav] 2018 Jun; Vol. 17 (5), pp. e12451. Date of Electronic Publication: 2018 Jan 17.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Social Isolation*
Alzheimer Disease/*metabolism
Alzheimer Disease/*psychology
Brain/*metabolism
Drosophila Proteins/*metabolism
Iron Regulatory Protein 1/*metabolism
Alzheimer Disease/genetics ; Amyloid beta-Peptides/metabolism ; Animals ; Behavior, Animal/physiology ; Disease Models, Animal ; Down-Regulation ; Drosophila Proteins/genetics ; Drosophila melanogaster ; Female ; Housing, Animal ; Iron Regulatory Protein 1/genetics ; Male ; Neurons/metabolism ; Peptide Fragments/metabolism

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 12.

Tytuł:: Iron Homeostasis in the CNS: An Overview of the Pathological Consequences of Iron Metabolism Disruption.
Autorzy:: Porras CA; Eunice Kennedy Shriver National Institute of Child Health and Development, Bethesda, MD 20892, USA.
Rouault TA; Eunice Kennedy Shriver National Institute of Child Health and Development, Bethesda, MD 20892, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2022 Apr 19; Vol. 23 (9). Date of Electronic Publication: 2022 Apr 19.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Iron Metabolism Disorders*/metabolism
Neurodegenerative Diseases*/metabolism
Animals ; Central Nervous System/metabolism ; Homeostasis ; Humans ; Iron/metabolism ; Iron Regulatory Protein 2/metabolism

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 13.

Tytuł:: Iron insufficiency compromises motor neurons and their mitochondrial function in Irp2-null mice.
Autorzy:: Jeong SY; Eunice Kennedy Shriver National Institute of Child Health and Development, National Institutes of Health, Bethesda, Maryland, United States of America.
Crooks DR
Wilson-Ollivierre H
Ghosh MC
Sougrat R
Lee J
Cooperman S
Mitchell JB
Beaumont C
Rouault TA; Pokaż więcej
Źródło:: PloS one [PLoS One] 2011; Vol. 6 (10), pp. e25404. Date of Electronic Publication: 2011 Oct 07.
Typ publikacji:: Journal Article; Research Support, N.I.H., Intramural
MeSH Terms:: Gene Deletion*
Iron Deficiencies*
Iron Regulatory Protein 2/*deficiency
Iron Regulatory Protein 2/*genetics
Mitochondria/*metabolism
Motor Neurons/*metabolism
Motor Neurons/*pathology
Animals ; Apoferritins/biosynthesis ; Atrophy/metabolism ; Axons/drug effects ; Axons/metabolism ; Axons/pathology ; Biomarkers/metabolism ; Brain/drug effects ; Brain/metabolism ; Brain/pathology ; Cyclic N-Oxides/pharmacology ; Homeostasis/drug effects ; Homeostasis/genetics ; Iron/metabolism ; Iron Regulatory Protein 1/deficiency ; Iron Regulatory Protein 1/metabolism ; Mice ; Mitochondria/drug effects ; Mitochondria/genetics ; Mitochondria/pathology ; Motor Neurons/drug effects ; Oxidative Stress/drug effects ; Oxidative Stress/genetics ; Spin Labels ; Spinal Cord/drug effects ; Spinal Cord/metabolism ; Spinal Cord/pathology

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 14.

Tytuł:: A drastic superoxide-dependent oxidative stress is prerequisite for the down-regulation of IRP1: Insights from studies on SOD1-deficient mice and macrophages treated with paraquat.
Autorzy:: Milczarek A; Department of Molecular Biology, Institute of Genetics and Animal Breeding, Polish Academy of Sciences, Jastrzębiec, Poland.
Starzyński RR; Department of Molecular Biology, Institute of Genetics and Animal Breeding, Polish Academy of Sciences, Jastrzębiec, Poland.
Styś A; Department of Molecular Biology, Institute of Genetics and Animal Breeding, Polish Academy of Sciences, Jastrzębiec, Poland.
Jończy A; Department of Molecular Biology, Institute of Genetics and Animal Breeding, Polish Academy of Sciences, Jastrzębiec, Poland.
Staroń R; Department of Molecular Biology, Institute of Genetics and Animal Breeding, Polish Academy of Sciences, Jastrzębiec, Poland.
Grzelak A; Department of Molecular Biophysics, University of Łódź, Łódź, Poland.
Lipiński P; Department of Molecular Biology, Institute of Genetics and Animal Breeding, Polish Academy of Sciences, Jastrzębiec, Poland.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2017 May 19; Vol. 12 (5), pp. e0176800. Date of Electronic Publication: 2017 May 19 (Print Publication: 2017).
Typ publikacji:: Journal Article
MeSH Terms:: Down-Regulation/*drug effects
Iron Regulatory Protein 1/*metabolism
Macrophages/*drug effects
Oxidative Stress/*drug effects
Paraquat/*pharmacology
Superoxide Dismutase-1/*deficiency
Superoxides/*metabolism
Animals ; Apoferritins/genetics ; Dose-Response Relationship, Drug ; Gene Expression Regulation/drug effects ; Iron Regulatory Protein 1/genetics ; Kidney/drug effects ; Kidney/metabolism ; Liver/drug effects ; Liver/metabolism ; Low Density Lipoprotein Receptor-Related Protein-1 ; Macrophages/cytology ; Macrophages/metabolism ; Mice ; RAW 264.7 Cells ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Receptors, LDL/deficiency ; Receptors, LDL/metabolism ; Tumor Suppressor Proteins/deficiency ; Tumor Suppressor Proteins/metabolism

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 15.

Tytuł:: Chlamydia trachomatis alters iron-regulatory protein-1 binding capacity and modulates cellular iron homeostasis in HeLa-229 cells.
Autorzy:: Vardhan H; Division of Microbiology/Tissue Culture, Institute of Pathology, Indian Council of Medical Research (ICMR), Safdarjung Hospital Campus, New Delhi, Pin 110029, India.
Bhengraj AR
Jha R
Singh Mittal A; Pokaż więcej
Źródło:: Journal of biomedicine & biotechnology [J Biomed Biotechnol] 2009; Vol. 2009, pp. 342032. Date of Electronic Publication: 2009 Aug 16.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Chlamydia Infections/*metabolism
Chlamydia trachomatis/*metabolism
Iron/*metabolism
Iron Regulatory Protein 1/*metabolism
Analysis of Variance ; Apoferritins/biosynthesis ; Apoferritins/genetics ; Apoferritins/metabolism ; Chlamydia Infections/genetics ; Down-Regulation ; HeLa Cells ; Humans ; Iron Regulatory Protein 1/biosynthesis ; Iron Regulatory Protein 1/genetics ; Iron Regulatory Protein 2/biosynthesis ; Iron Regulatory Protein 2/genetics ; Iron Regulatory Protein 2/metabolism ; Protein Binding ; Receptors, Transferrin/biosynthesis ; Receptors, Transferrin/genetics ; Receptors, Transferrin/metabolism ; Response Elements ; Up-Regulation

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 16.

Tytuł:: Iron-dependent degradation of IRP2 requires its C-terminal region and IRP structural integrity.
Autorzy:: Wang J; Lady Davis Institute for Medical Research, Sir Mortimer B, Davis Jewish General Hospital, Montreal, Quebec, Canada. />Chen G
Lee J
Pantopoulos K; Pokaż więcej
Źródło:: BMC molecular biology [BMC Mol Biol] 2008 Jan 28; Vol. 9, pp. 15. Date of Electronic Publication: 2008 Jan 28.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Iron/*metabolism
Iron Regulatory Protein 2/*chemistry
Proteasome Endopeptidase Complex/*metabolism
Cell Line, Tumor ; Humans ; Iron Regulatory Protein 1/chemistry ; Iron Regulatory Protein 1/genetics ; Iron Regulatory Protein 1/metabolism ; Iron Regulatory Protein 2/genetics ; Iron Regulatory Protein 2/metabolism ; Mutation ; Protein Structure, Tertiary ; Ubiquitination

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 17.

Tytuł:: Control of iron homeostasis by an iron-regulated ubiquitin ligase.
Autorzy:: Vashisht AA; Department of Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.
Zumbrennen KB
Huang X
Powers DN
Durazo A
Sun D
Bhaskaran N
Persson A
Uhlen M
Sangfelt O
Spruck C
Leibold EA
Wohlschlegel JA; Pokaż więcej
Źródło:: Science (New York, N.Y.) [Science] 2009 Oct 30; Vol. 326 (5953), pp. 718-21. Date of Electronic Publication: 2009 Sep 17.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: F-Box Proteins/*metabolism
Iron/*metabolism
Iron Regulatory Protein 2/*metabolism
Ubiquitin-Protein Ligases/*metabolism
Cell Line ; Cullin Proteins/metabolism ; Hemerythrin/metabolism ; Homeostasis ; Humans ; Iron Regulatory Protein 1/metabolism ; Oxygen/metabolism ; Protein Structure, Tertiary ; Recombinant Proteins/metabolism ; SKP Cullin F-Box Protein Ligases/metabolism ; Ubiquitin-Protein Ligase Complexes

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 18.

Tytuł:: The Role of GSH in Intracellular Iron Trafficking.
Autorzy:: Hider R; Institute of Pharmaceutical Science, King's College London, London SE1 9NH, UK.
Aviles MV; Institute of Pharmaceutical Science, King's College London, London SE1 9NH, UK.
Chen YL; Institute of Pharmaceutical Science, King's College London, London SE1 9NH, UK.
Latunde-Dada GO; Institute of Pharmaceutical Science, King's College London, London SE1 9NH, UK.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Jan 28; Vol. 22 (3). Date of Electronic Publication: 2021 Jan 28.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Carnosine/*metabolism
Glutathione/*metabolism
Histidine/*metabolism
Iron/*metabolism
Iron Chelating Agents/*metabolism
Brain/cytology ; Brain/metabolism ; DNA-Binding Proteins/genetics ; DNA-Binding Proteins/metabolism ; Gene Expression Regulation ; Humans ; Hydrogen-Ion Concentration ; Hypoxia-Inducible Factor 1, alpha Subunit/genetics ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism ; Iron Regulatory Protein 1/genetics ; Iron Regulatory Protein 1/metabolism ; Iron Regulatory Protein 2/genetics ; Iron Regulatory Protein 2/metabolism ; Kidney/cytology ; Kidney/metabolism ; Mitochondria/genetics ; Mitochondria/metabolism ; Muscles/cytology ; Muscles/metabolism ; RNA-Binding Proteins/genetics ; RNA-Binding Proteins/metabolism

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 19.

Tytuł:: Regulatory Connections between Iron and Glucose Metabolism.
Autorzy:: Fillebeen C; Lady Davis Institute for Medical Research, Jewish General Hospital and Department of Medicine, McGill University, Montreal, QC H3Y 1P3, Canada.
Lam NH; Department of Biology, York University, Toronto, ON M3J 1P3, Canada.
Chow S; Department of Biology, York University, Toronto, ON M3J 1P3, Canada.
Botta A; Department of Biology, York University, Toronto, ON M3J 1P3, Canada.
Sweeney G; Department of Biology, York University, Toronto, ON M3J 1P3, Canada.
Pantopoulos K; Lady Davis Institute for Medical Research, Jewish General Hospital and Department of Medicine, McGill University, Montreal, QC H3Y 1P3, Canada.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2020 Oct 21; Vol. 21 (20). Date of Electronic Publication: 2020 Oct 21.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Glucose/*metabolism
Iron/*metabolism
Metabolic Syndrome/*metabolism
Animals ; Blood Glucose/metabolism ; Energy Metabolism ; Glucose Transport Proteins, Facilitative/metabolism ; Humans ; Iron Regulatory Protein 1/metabolism ; Iron Regulatory Protein 2/metabolism ; Metabolomics ; Mice

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 20.

Tytuł:: Relieving ferroptosis may partially reverse neurodegeneration of the auditory cortex.
Autorzy:: Chen X; Department of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Li D; Department of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Sun HY; Department of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Wang WW; Department of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Wu H; Department of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Kong W; Department of Endocrinology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Kong WJ; Department of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Pokaż więcej
Źródło:: The FEBS journal [FEBS J] 2020 Nov; Vol. 287 (21), pp. 4747-4766. Date of Electronic Publication: 2020 Mar 17.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Apoptosis/*genetics
Auditory Cortex/*metabolism
Ferroptosis/*genetics
Neurodegenerative Diseases/*genetics
Age Factors ; Animals ; Apoptosis/drug effects ; Auditory Cortex/drug effects ; Auditory Cortex/ultrastructure ; Chelating Agents/pharmacology ; Deferoxamine/pharmacology ; Ferroptosis/drug effects ; Gene Expression ; Humans ; Iron/metabolism ; Iron Regulatory Protein 2/genetics ; Iron Regulatory Protein 2/metabolism ; Male ; Neurodegenerative Diseases/metabolism ; Neurodegenerative Diseases/prevention & control ; PC12 Cells ; RNA Interference ; Rats ; Rats, Sprague-Dawley ; Receptors, Transferrin/genetics ; Receptors, Transferrin/metabolism

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Informacja

Wyszukujesz frazę ""Iron regulatory protein"" wg kryterium: Temat

Źródło danych

Ogranicz do:

Ogranicz do bazy

Typ dokumentu

Temat

Wydawca

Publikacja

Język