Temat: "Isatin" - OpacWWW - Prolib Integro

Skocz do pozycji: 1.

Tytuł:: A novel isatin Schiff based cerium complex: synthesis, characterization, antimicrobial activity and molecular docking studies.
Autorzy:: Saad HE; Department of Chemistry, Faculty of Science, Tanta University, Tanta, 31527, Egypt.
El-Reash GMA; Department of Chemistry, Faculty of Science, Mansoura University, Mansoura, 35516, Egypt.
Gaber M; Department of Chemistry, Faculty of Science, Tanta University, Tanta, 31527, Egypt.
Hashem MA; Department of Chemistry, Faculty of Science, Mansoura University, Mansoura, 35516, Egypt. mohamed_.
El-Reash YGA; Department of Chemistry, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), P.O. Box, 90950, 11623, Riyadh, Saudi Arabia.
Elamin NY; Department of Chemistry, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), P.O. Box, 90950, 11623, Riyadh, Saudi Arabia.; Department of Chemistry, Sudan University of Science and Technology, P.O. Box 407, Khartoum, 11111, Sudan.
Elamin MR; Department of Chemistry, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), P.O. Box, 90950, 11623, Riyadh, Saudi Arabia.
El-Sayed YS; Department of Chemistry, Faculty of Science, Tanta University, Tanta, 31527, Egypt.; Pokaż więcej
Źródło:: BMC genomics [BMC Genomics] 2024 Feb 08; Vol. 25 (1), pp. 162. Date of Electronic Publication: 2024 Feb 08.
Typ publikacji:: Journal Article
MeSH Terms:: Isatin*/pharmacology
Isatin*/chemistry
Cerium*/pharmacology
Molecular Docking Simulation ; Spectroscopy, Fourier Transform Infrared ; Schiff Bases/pharmacology ; Schiff Bases/chemistry ; Computer Simulation ; Ligands ; Anti-Bacterial Agents/pharmacology ; Microbial Sensitivity Tests

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Skocz do pozycji: 2.

Tytuł:: 1,2,3-Triazole Hybrids Containing Isatins and Phenolic Moieties: Regioselective Synthesis and Molecular Docking Studies.
Autorzy:: Maiuolo L; Department of Chemistry and Chemical Technologies, University of Calabria, 87036 Rende, Italy.
Tallarida MA; RINA Consulting-Centro Sviluppo Materiali SpA, Via di Castel Romano 100, 00128 Rome, Italy.
Meduri A; RINA Consulting-Centro Sviluppo Materiali SpA, Zona Industriale San Pietro Lametino, Comparto 1, 88046 Lamezia Terme, CZ, Italy.
Fiorani G; Department Molecular Sciences and Nanosystems, University Ca' Foscari Venezia, 30172 Mestre, VE, Italy.
Jiritano A; Department of Chemistry and Chemical Technologies, University of Calabria, 87036 Rende, Italy.
De Nino A; Department of Chemistry and Chemical Technologies, University of Calabria, 87036 Rende, Italy.
Algieri V; IRCCS NEUROMED-Istituto Neurologico Mediterraneo, Via Atinense 18, 86077 Pozzilli, IS, Italy.
Costanzo P; Department of Chemistry and Chemical Technologies, University of Calabria, 87036 Rende, Italy.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2024 Mar 30; Vol. 29 (7). Date of Electronic Publication: 2024 Mar 30.
Typ publikacji:: Journal Article
MeSH Terms:: Isatin*
Molecular Docking Simulation ; Phenols ; Alkynes ; Triazoles

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Skocz do pozycji: 3.

Tytuł:: Unraveling the Dynamics of Host-Microbiota Indole Metabolism: An Investigation of Indole, Indolin-2-one, Isatin, and 3-Hydroxyindolin-2-one.
Autorzy:: Kunevičius A; Department of Biological Models, Institute of Biochemistry, Life Sciences Center, Vilnius University, Sauletekio av. 7, LT-10257 Vilnius, Lithuania.
Sadauskas M; Department of Molecular Microbiology and Biotechnology, Institute of Biochemistry, Life Sciences Center, Vilnius University, Sauletekio av. 7, LT-10257 Vilnius, Lithuania.
Raudytė J; Department of Biological Models, Institute of Biochemistry, Life Sciences Center, Vilnius University, Sauletekio av. 7, LT-10257 Vilnius, Lithuania.
Meškys R; Department of Molecular Microbiology and Biotechnology, Institute of Biochemistry, Life Sciences Center, Vilnius University, Sauletekio av. 7, LT-10257 Vilnius, Lithuania.
Burokas A; Department of Biological Models, Institute of Biochemistry, Life Sciences Center, Vilnius University, Sauletekio av. 7, LT-10257 Vilnius, Lithuania.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2024 Feb 24; Vol. 29 (5). Date of Electronic Publication: 2024 Feb 24.
Typ publikacji:: Journal Article
MeSH Terms:: Isatin*
Microbiota*
Mice ; Animals ; Mice, Inbred C57BL ; Indoles/metabolism

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Skocz do pozycji: 4.

Tytuł:: Discovery of sulfonamide-tethered isatin derivatives as novel anticancer agents and VEGFR-2 inhibitors.
Autorzy:: Shaldam MA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, Egypt.
Almahli H; Department of Chemistry, University of Cambridge, Cambridge, UK.
Angeli A; Department of NEUROFARBA, Section of Pharmaceutical and Nutraceutical Sciences, University of Florence, Sesto Fiorentino, Italy.
Badi RM; Department of Medical Physiology, College of Medicine, King Khalid University, Abha, Saudi Arabia.
Khaleel EF; Department of Medical Physiology, College of Medicine, King Khalid University, Abha, Saudi Arabia.
Zain-Alabdeen AI; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Tanta University, Tanta, Egypt.
Elsayed ZM; Scientific Research and Innovation Support Unit, Faculty of Pharmacy, Kafrelsheikh Uinversity, Kafrelsheikh, Egypt.
Elkaeed EB; Department of Pharmaceutical Sciences, College of Pharmacy, AlMaarefa University, Riyadh, Saudi Arabia.; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt.
Salem R; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, Egypt.
Supuran CT; Department of NEUROFARBA, Section of Pharmaceutical and Nutraceutical Sciences, University of Florence, Sesto Fiorentino, Italy.
Eldehna WM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, Egypt.; School of Biotechnology, Badr University in Cairo, Badr City, Egypt.
Tawfik HO; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Tanta University, Tanta, Egypt.; Pokaż więcej
Źródło:: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2023 Dec; Vol. 38 (1), pp. 2203389.
Typ publikacji:: Journal Article
MeSH Terms:: Carbonic Anhydrases*/metabolism
Isatin*/pharmacology
Isatin*/chemistry
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/chemistry
Molecular Structure ; Structure-Activity Relationship ; Vascular Endothelial Growth Factor Receptor-2 ; Sulfonamides/pharmacology ; Sulfonamides/chemistry ; Carbonic Anhydrase Inhibitors/pharmacology ; Carbonic Anhydrase Inhibitors/chemistry ; Carbonic Anhydrase IX ; Antigens, Neoplasm/metabolism

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Skocz do pozycji: 5.

Tytuł:: Identification of sulphonamide-tethered N -((triazol-4-yl)methyl)isatin derivatives as inhibitors of SARS-CoV-2 main protease.
Autorzy:: ElNaggar MH; Department of Pharmacognosy, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, Egypt.
Elgazar AA; Department of Pharmacognosy, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, Egypt.
Gamal G; Department of Pharmacognosy, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, Egypt.
Hamed SM; Scientific Research and Innovation Support Unit, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, Egypt.
Elsayed ZM; Scientific Research and Innovation Support Unit, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, Egypt.
El-Ashrey MK; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Cairo University, Cairo, Egypt.
Abood A; Chemistry of Natural and microbial products, National Research center, Egypt.; Department of Bioscience, University of Kent, Canterbury, UK.
El Hassab MA; Department of Medicinal Chemistry, Faculty of Pharmacy, King Salman International University (KSIU), Egypt.
Soliman AM; Department of Microbiology and Immunology, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, Egypt.
El-Domany RA; Department of Microbiology and Immunology, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, Egypt.
Badria FA; Department of Pharmacognosy, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.
Supuran CT; Department of NEUROFARBA, Section of Pharmaceutical and Nutraceutical Sciences, University of Florence, Firenze, Italy.
Eldehna WM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, Egypt.; School of Biotechnology, Badr University in Cairo, Badr City, Egypt.; Pokaż więcej
Źródło:: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2023 Dec; Vol. 38 (1), pp. 2234665.
Typ publikacji:: Journal Article
MeSH Terms:: COVID-19*
Isatin*
Humans ; SARS-CoV-2 ; Sulfanilamide ; Sulfonamides/pharmacology

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Skocz do pozycji: 6.

Tytuł:: Bimetallic bis -Aroyldihydrazone-Isatin Complexes of High O=V(IV) and Low Cu(II) Valent Ions as Effective Biological Reagents for Antimicrobial and Anticancer Assays.
Autorzy:: Khalil A; Department of Chemistry, College of Science, King Faisal University, P.O. Box 400, Al-Ahsa 31982, Saudi Arabia.; Chemistry Department, Faculty of Science, Zagazig University, Zagazig 44519, Egypt.
Adam MSS; Department of Chemistry, College of Science, King Faisal University, P.O. Box 400, Al-Ahsa 31982, Saudi Arabia.; Department of Chemistry, Faculty of Science, Sohag University, Sohag 82534, Egypt.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2024 Jan 15; Vol. 29 (2). Date of Electronic Publication: 2024 Jan 15.
Typ publikacji:: Journal Article
MeSH Terms:: Isatin*
Anti-Infective Agents*/pharmacology
Ligands ; Biological Assay ; Ions

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Skocz do pozycji: 7.

Tytuł:: Isatin-tethered halogen-containing acylhydrazone derivatives as monoamine oxidase inhibitor with neuroprotective effect.
Autorzy:: Kumar S; Department of Pharmaceutical Chemistry, Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, AIMS Health Sciences Campus, Kochi, 682041, India.
Oh JM; Department of Pharmacy, and Research Institute of Life Pharmaceutical Sciences, Sunchon National University, Suncheon, 57922, Republic of Korea.
Prabhakaran P; Department of Pharmaceutical Chemistry, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Mysuru, 570015, India.
Awasti A; Department of Pharmaceutical Chemistry, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Mysuru, 570015, India.
Kim H; Department of Pharmacy, and Research Institute of Life Pharmaceutical Sciences, Sunchon National University, Suncheon, 57922, Republic of Korea. .
Mathew B; Department of Pharmaceutical Chemistry, Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, AIMS Health Sciences Campus, Kochi, 682041, India. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Jan 13; Vol. 14 (1), pp. 1264. Date of Electronic Publication: 2024 Jan 13.
Typ publikacji:: Journal Article
MeSH Terms:: Isatin*/pharmacology
Neuroprotective Agents*/pharmacology
Neuroblastoma*
Humans ; Monoamine Oxidase Inhibitors/pharmacology ; Monoamine Oxidase Inhibitors/chemistry ; Molecular Docking Simulation ; Lipopolysaccharides ; Structure-Activity Relationship ; Monoamine Oxidase/metabolism ; Coloring Agents/pharmacology

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Skocz do pozycji: 8.

Tytuł:: Novel 7-Deazapurine Incorporating Isatin Hybrid Compounds as Protein Kinase Inhibitors: Design, Synthesis, In Silico Studies, and Antiproliferative Evaluation.
Autorzy:: Alanazi MM; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.
Alanazi AS; Department of Pharmaceutical Sciences, College of Pharmacy, Princess Nourah Bint Abdulrahman University, Riyadh 11671, Saudi Arabia.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2023 Aug 04; Vol. 28 (15). Date of Electronic Publication: 2023 Aug 04.
Typ publikacji:: Journal Article
MeSH Terms:: Isatin*/pharmacology
Isatin*/therapeutic use
Antineoplastic Agents*
Neoplasms*/drug therapy
Humans ; Protein Kinase Inhibitors ; Drug Screening Assays, Antitumor ; Cell Proliferation ; Structure-Activity Relationship ; Molecular Structure ; Cell Line, Tumor

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Skocz do pozycji: 9.

Tytuł:: Anticancer and Antiphytopathogenic Activity of Fluorinated Isatins and Their Water-Soluble Hydrazone Derivatives.
Autorzy:: Bogdanov AV; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Akad. Arbuzov St. 8, Kazan 420088, Russia.
Neganova M; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Akad. Arbuzov St. 8, Kazan 420088, Russia.; Institute of Physiologically Active Compounds at Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Severnij Pr. 1, Chernogolovka 142432, Russia.
Voloshina A; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Akad. Arbuzov St. 8, Kazan 420088, Russia.
Lyubina A; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Akad. Arbuzov St. 8, Kazan 420088, Russia.
Amerhanova S; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Akad. Arbuzov St. 8, Kazan 420088, Russia.
Litvinov IA; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Akad. Arbuzov St. 8, Kazan 420088, Russia.
Tsivileva O; Institute of Biochemistry and Physiology of Plants and Microorganisms, Saratov Scientific Centre of the Russian Academy of Sciences, Entuziastov Ave. 13, Saratov 410049, Russia.
Akylbekov N; Laboratory of Engineering Profile 'Physical and Chemical Methods of Analysis', Korkyt Ata Kyzylorda University, Aitekebie Str. 29A, Kyzylorda 120014, Kazakhstan.
Zhapparbergenov R; Laboratory of Engineering Profile 'Physical and Chemical Methods of Analysis', Korkyt Ata Kyzylorda University, Aitekebie Str. 29A, Kyzylorda 120014, Kazakhstan.
Valiullina Z; Department of Pharmacology, Bashkir State Medical University, Lenin St. 8, Ufa 450008, Russia.
Samorodov AV; Department of Pharmacology, Bashkir State Medical University, Lenin St. 8, Ufa 450008, Russia.
Alabugin I; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Akad. Arbuzov St. 8, Kazan 420088, Russia.; Department of Chemistry and Biochemistry, Florida State University, 95 Chieftan Way, Tallahassee, FL 32306-4390, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Oct 12; Vol. 24 (20). Date of Electronic Publication: 2023 Oct 12.
Typ publikacji:: Journal Article
MeSH Terms:: Isatin*/pharmacology
Antineoplastic Agents*/pharmacology
Hydrazones/pharmacology ; Water/pharmacology ; Apoptosis ; Structure-Activity Relationship

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Skocz do pozycji: 10.

Tytuł:: Assembling a Cinnamyl Pharmacophore in the C3-Position of Substituted Isatins via Microwave-Assisted Synthesis: Development of a New Class of Monoamine Oxidase-B Inhibitors for the Treatment of Parkinson's Disease.
Autorzy:: Manoharan A; Department of Pharmaceutical Chemistry, Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, AIMS Health Sciences Campus, Kochi 682 041, India.
Oh JM; Department of Pharmacy, Research Institute of Life Pharmaceutical Sciences, Sunchon National University, Suncheon 57922, Republic of Korea.
Benny F; Department of Pharmaceutical Chemistry, Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, AIMS Health Sciences Campus, Kochi 682 041, India.
Kumar S; Department of Pharmaceutical Chemistry, Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, AIMS Health Sciences Campus, Kochi 682 041, India.
Abdelgawad MA; Department of Pharmaceutical Chemistry, College of Pharmacy, Jouf University, Sakaka 72341, Saudi Arabia.; Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef 62514, Egypt.
Ghoneim MM; Department of Pharmacy Practice, College of Pharmacy, AlMaarefa University, Ad Diriyah 13713, Saudi Arabia.; Pharmacognosy and Medicinal Plants Department, Faculty of Pharmacy, Al-Azhar University, Cairo 11884, Egypt.
Shaker ME; Department of Pharmacology, College of Pharmacy, Jouf University, Sakaka 72341, Saudi Arabia.; Department of Pharmacology & Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt.
El-Sherbiny M; Department of Basic Medical Sciences, College of Medicine, AlMaarefa University, Riyadh 11597, Saudi Arabia.; Department of Anatomy, Faculty of Medicine, Mansoura University, Mansoura 35516, Egypt.
Almohaimeed HM; Department of Basic Science, College of Medicine, Princess Nourah bint Abdulrahman University, Riyadh 11671, Saudi Arabia.
Gahtori P; School of Pharmacy, Graphic Era Hill University, Dehradun 248002, India.
Kim H; Department of Pharmacy, Research Institute of Life Pharmaceutical Sciences, Sunchon National University, Suncheon 57922, Republic of Korea.
Mathew B; Department of Pharmaceutical Chemistry, Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, AIMS Health Sciences Campus, Kochi 682 041, India.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2023 Aug 21; Vol. 28 (16). Date of Electronic Publication: 2023 Aug 21.
Typ publikacji:: Journal Article
MeSH Terms:: Parkinson Disease*/drug therapy
Isatin*
Neuroblastoma*
Antipsychotic Agents*
Humans ; Microwaves ; Molecular Docking Simulation ; Pargyline ; Pharmacophore ; Dopamine Agents ; Monoamine Oxidase

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Skocz do pozycji: 11.

Tytuł:: Evaluation of Anti-Neuroinflammatory Activity of Isatin Derivatives in Activated Microglia.
Autorzy:: Cenalmor A; Facultad de Ciencias Experimentales, Universidad Francisco de Vitoria, Pozuelo de Alarcón, 28223 Madrid, Spain.
Pascual E; Facultad de Ciencias Experimentales, Universidad Francisco de Vitoria, Pozuelo de Alarcón, 28223 Madrid, Spain.
Gil-Manso S; Laboratory of Immune-Regulation, Gregorio Marañón Health Research Institute (IISGM), 28009 Madrid, Spain.
Correa-Rocha R; Laboratory of Immune-Regulation, Gregorio Marañón Health Research Institute (IISGM), 28009 Madrid, Spain.
Suárez JR; Departamento de Química en Ciencias Farmacéuticas, Facultad de Farmacia, Universidad Complutense de Madrid, 28040 Madrid, Spain.
García-Álvarez I; Facultad de Ciencias Experimentales, Universidad Francisco de Vitoria, Pozuelo de Alarcón, 28223 Madrid, Spain.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2023 Jun 20; Vol. 28 (12). Date of Electronic Publication: 2023 Jun 20.
Typ publikacji:: Journal Article
MeSH Terms:: Isatin*/pharmacology
Neuroprotective Agents*/pharmacology
Humans ; Anti-Inflammatory Agents/pharmacology ; Microglia/metabolism ; Neuroinflammatory Diseases ; NF-kappa B/metabolism ; Lipopolysaccharides/pharmacology ; Nitric Oxide/metabolism ; Tumor Necrosis Factor-alpha/metabolism ; Nitric Oxide Synthase Type II/metabolism

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Skocz do pozycji: 12.

Tytuł:: New 6'-Amino-5'-cyano-2-oxo-1,2-dihydro-1' H -spiro[indole-3,4'-pyridine]-3'-carboxamides: Synthesis, Reactions, Molecular Docking Studies and Biological Activity.
Autorzy:: Dotsenko VV; Department of Organic Chemistry and Technologies, Kuban State University, 149 Stavropolskaya St., 350040 Krasnodar, Russia.; Department of Chemistry, North Caucasus Federal University, 1a Pushkin St., 355017 Stavropol, Russia.
Jassim NT; Department of Organic Chemistry and Technologies, Kuban State University, 149 Stavropolskaya St., 350040 Krasnodar, Russia.
Temerdashev AZ; Department of Analytical Chemistry, Kuban State University, 149 Stavropolskaya St., 350040 Krasnodar, Russia.
Abdul-Hussein ZR; Department of Pathological Analyses, College of Science, University of Basra, P.O. Box 49, Basrah 61004, Iraq.
Aksenov NA; Department of Chemistry, North Caucasus Federal University, 1a Pushkin St., 355017 Stavropol, Russia.
Aksenova IV; Department of Chemistry, North Caucasus Federal University, 1a Pushkin St., 355017 Stavropol, Russia.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2023 Apr 02; Vol. 28 (7). Date of Electronic Publication: 2023 Apr 02.
Typ publikacji:: Journal Article
MeSH Terms:: Pyridines*
Isatin*
Molecular Docking Simulation ; Indoles/pharmacology ; Indoles/chemistry ; Magnetic Resonance Spectroscopy

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Skocz do pozycji: 13.

Tytuł:: Dipolarophile-Controlled Regioselective 1,3-Dipolar Cycloaddition: A Switchable Divergent Access to Functionalized N -Fused Pyrrolidinyl Spirooxindoles.
Autorzy:: Wang Y; Colleage of Vocational and Technical Education, Yunnan Normal University, Kunming 650092, China.
Yan L; Colleage of Vocational and Technical Education, Yunnan Normal University, Kunming 650092, China.
Yan Y; Colleage of Vocational and Technical Education, Yunnan Normal University, Kunming 650092, China.
Li S; Colleage of Vocational and Technical Education, Yunnan Normal University, Kunming 650092, China.
Lu H; Colleage of Vocational and Technical Education, Yunnan Normal University, Kunming 650092, China.
Liu J; Colleage of Vocational and Technical Education, Yunnan Normal University, Kunming 650092, China.
Dong J; Colleage of Chemistry and Environmental Science, Qujing Normal University, Qujing 655011, China.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Feb 13; Vol. 24 (4). Date of Electronic Publication: 2023 Feb 13.
Typ publikacji:: Journal Article
MeSH Terms:: Isatin*/chemistry
Cycloaddition Reaction

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Skocz do pozycji: 14.

Tytuł:: Spirooxindole: A Versatile Biologically Active Heterocyclic Scaffold.
Autorzy:: Panda SS; Department of Chemistry and Physics, Augusta University, Augusta, GA 30912, USA.
Girgis AS; Department of Pesticide Chemistry, National Research Centre, Dokki, Giza 12622, Egypt.
Aziz MN; Department of Pesticide Chemistry, National Research Centre, Dokki, Giza 12622, Egypt.
Bekheit MS; Department of Pesticide Chemistry, National Research Centre, Dokki, Giza 12622, Egypt.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2023 Jan 07; Vol. 28 (2). Date of Electronic Publication: 2023 Jan 07.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Spiro Compounds*/pharmacology
Spiro Compounds*/chemistry
Isatin*/pharmacology
Isatin*/chemistry
Indoles/chemistry

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Skocz do pozycji: 15.

Tytuł:: New quinoline and isatin derivatives as apoptotic VEGFR-2 inhibitors: design, synthesis, anti-proliferative activity, docking, ADMET, toxicity, and MD simulation studies.
Autorzy:: Elkaeed EB; Department of Pharmaceutical Sciences, College of Pharmacy, AlMaarefa University, Riyadh, 13713, Saudi Arabia.
Taghour MS; Pharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt.
Mahdy HA; Pharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt.
Eldehna WM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, Egypt.
El-Deeb NM; Biopharmaceutical Products Research Department, Genetic Engineering and Biotechnology Research Institute, City of Scientific Research and Technological Applications (SRTA-City), Alexandria, Egypt.; Pharmaceutical and Fermentation Industries Development Center, City of Scientific Research and Technological Applications (SRTA city), Alexandria, Egypt.
Kenawy AM; Nucleic Acids Research Department, Genetic Engineering and Biotechnology Research Institute. City of Scientific Research and Technological Applications (SRTA-City), Alexandria, Egypt.
A Alsfouk B; Department of Pharmaceutical Sciences, College of Pharmacy, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.
Dahab MA; Pharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt.
Metwaly AM; Biopharmaceutical Products Research Department, Genetic Engineering and Biotechnology Research Institute, City of Scientific Research and Technological Applications (SRTA-City), Alexandria, Egypt.; Pharmacognosy and Medicinal Plants Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt.
Eissa IH; Pharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt.
El-Zahabi MA; Pharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt.; Pokaż więcej
Źródło:: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2022 Dec; Vol. 37 (1), pp. 2191-2205.
Typ publikacji:: Journal Article
MeSH Terms:: Antineoplastic Agents*/pharmacology
Isatin*/pharmacology
Quinolines*/pharmacology
Animals ; Caco-2 Cells ; Cell Proliferation ; Chlorocebus aethiops ; Drug Screening Assays, Antitumor ; Humans ; Molecular Docking Simulation ; Molecular Structure ; Protein Kinase Inhibitors/pharmacology ; Structure-Activity Relationship ; Vascular Endothelial Growth Factor Receptor-2 ; Vero Cells

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Skocz do pozycji: 16.

Tytuł:: Synthesis, molecular docking, and biological evaluation of novel 1,2,4-triazole-isatin derivatives as potential Mycobacterium tuberculosis shikimate kinase inhibitors.
Autorzy:: Dadlani VG; Department of Pharmaceutical Chemistry, Dr. L. H. Hiranandani College of Pharmacy, Ulhasnagar, India.
Chhabhaiya H; Department of Pharmaceutical Chemistry, Dr. L. H. Hiranandani College of Pharmacy, Ulhasnagar, India.
Somani RR; Department of Pharmaceutical Chemistry, D Y Patil University School of Pharmacy, Navi Mumbai, India.
Tripathi PK; Institute of Pharmaceutical Sciences, University of Lucknow, Lucknow, India.; Pokaż więcej
Źródło:: Chemical biology & drug design [Chem Biol Drug Des] 2022 Aug; Vol. 100 (2), pp. 230-244. Date of Electronic Publication: 2022 Jun 06.
Typ publikacji:: Journal Article
MeSH Terms:: Antitubercular Agents*/chemistry
Antitubercular Agents*/pharmacology
Isatin*/chemistry
Isatin*/pharmacology
Mycobacterium tuberculosis*/drug effects
Phosphotransferases (Alcohol Group Acceptor)*/antagonists & inhibitors
Triazoles*/chemistry
Triazoles*/pharmacology
HEK293 Cells ; Humans ; Microbial Sensitivity Tests ; Molecular Docking Simulation ; Shikimic Acid ; Structure-Activity Relationship ; Tuberculosis/drug therapy

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Skocz do pozycji: 17.

Tytuł:: Synthesis and Biological Activity of Barbituric acid- linked Isatin Derivatives.
Autorzy:: Shahed, Mohammed S. Abdul
Mageed, Ahmed H.; Pokaż więcej
Źródło:: Egyptian Academic Journal of Biological Sciences, C Physiology & Molecular Biology. 2023, Vol. 15 Issue 2, p11-23. 13p.

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Skocz do pozycji: 18.

Tytuł:: Development of Novel Isatin-Tethered Quinolines as Anti-Tubercular Agents against Multi and Extensively Drug-Resistant Mycobacterium tuberculosis .
Autorzy:: Abdelrahman MA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Egyptian Russian University, Badr City 11829, Egypt.
Almahli H; Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, UK.
Al-Warhi T; Department of Chemistry, College of Science, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia.
Majrashi TA; Department of Pharmacognosy, College of Pharmacy, King Khalid University, Abha 61441, Saudi Arabia.
Abdel-Aziz MM; The Regional Center for Mycology and Biotechnology, Al-Azhar University, Cairo 11651, Egypt.
Eldehna WM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh 33516, Egypt.; School of Biotechnology, Badr University in Cairo, Cairo 11829, Egypt.
Said MA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Egyptian Russian University, Badr City 11829, Egypt.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2022 Dec 12; Vol. 27 (24). Date of Electronic Publication: 2022 Dec 12.
Typ publikacji:: Journal Article
MeSH Terms:: Mycobacterium tuberculosis*
Isatin*/pharmacology
Quinolines*/pharmacology
Antitubercular Agents/pharmacology ; Structure-Activity Relationship ; Drug Design ; Microbial Sensitivity Tests

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Skocz do pozycji: 19.

Tytuł:: Isatin Bis-Indole and Bis-Imidazothiazole Hybrids: Synthesis and Antimicrobial Activity.
Autorzy:: Bonvicini F; Department of Pharmacy and Biotechnology, Alma Mater Studiorum-University of Bologna, Via Massarenti 9, 40138 Bologna, Italy.
Locatelli A; Department of Pharmacy and Biotechnology, Alma Mater Studiorum-University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy.
Morigi R; Department of Pharmacy and Biotechnology, Alma Mater Studiorum-University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy.
Leoni A; Department of Pharmacy and Biotechnology, Alma Mater Studiorum-University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy.
Gentilomi GA; Department of Pharmacy and Biotechnology, Alma Mater Studiorum-University of Bologna, Via Massarenti 9, 40138 Bologna, Italy.; Division of Microbiology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Via Massarenti 9, 40138 Bologna, Italy.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2022 Sep 07; Vol. 27 (18). Date of Electronic Publication: 2022 Sep 07.
Typ publikacji:: Journal Article
MeSH Terms:: Anti-Infective Agents*/pharmacology
Isatin*/pharmacology
Anti-Bacterial Agents/pharmacology ; Candida albicans ; Escherichia coli ; Humans ; Indoles/pharmacology ; Microbial Sensitivity Tests ; Staphylococcus aureus ; Structure-Activity Relationship

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Skocz do pozycji: 20.

Tytuł:: An Efficient Route to 3,3'-Biindolinylidene-diones by Iron-Catalyzed Dimerization of Isatins.
Autorzy:: Jagtap RA; Organometallic Synthesis and Catalysis Lab, Organic Chemistry Division, CSIR - National Chemical Laboratory (CSIR - NCL), Dr. Homi Bhabha Road, Pune, 411 008, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201 002, India.
Pradhan C; Organometallic Synthesis and Catalysis Lab, Organic Chemistry Division, CSIR - National Chemical Laboratory (CSIR - NCL), Dr. Homi Bhabha Road, Pune, 411 008, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201 002, India.
Gonnade RG; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201 002, India.; Centre for Material Characterization, CSIR - National Chemical Laboratory (CSIR - NCL), Dr. Homi Bhabha Road, Pune, India.
Punji B; Organometallic Synthesis and Catalysis Lab, Organic Chemistry Division, CSIR - National Chemical Laboratory (CSIR - NCL), Dr. Homi Bhabha Road, Pune, 411 008, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201 002, India.; Pokaż więcej
Źródło:: Chemistry, an Asian journal [Chem Asian J] 2022 Aug 01; Vol. 17 (15), pp. e202200414. Date of Electronic Publication: 2022 Jun 10.
Typ publikacji:: Journal Article
MeSH Terms:: Iron*/chemistry
Isatin*/chemistry
Catalysis ; Dimerization ; Molecular Structure

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