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Tytuł:
Neuroprotective Effects of Aucubin against Cerebral Ischemia and Ischemia Injury through the Inhibition of the TLR4/NF-κB Inflammatory Signaling Pathway in Gerbils.
Autorzy:
Park JH; Department of Anatomy, College of Korean Medicine, Dongguk University, Gyeongju 38066, Republic of Korea.
Lee TK; Department of Food Science and Nutrition, Hallym University, Chuncheon 24252, Republic of Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung 25457, Republic of Korea.
Ahn JH; Department of Physical Therapy, College of Health Science, Youngsan University, Yangsan 50510, Republic of Korea.
Shin MC; Department of Emergency Medicine, Kangwon National University Hospital, School of Medicine, Kangwon National University, Chuncheon 24289, Republic of Korea.
Cho JH; Department of Emergency Medicine, Kangwon National University Hospital, School of Medicine, Kangwon National University, Chuncheon 24289, Republic of Korea.
Won MH; Department of Emergency Medicine, Kangwon National University Hospital, School of Medicine, Kangwon National University, Chuncheon 24289, Republic of Korea.
Kang IJ; Department of Food Science and Nutrition, Hallym University, Chuncheon 24252, Republic of Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Mar 19; Vol. 25 (6). Date of Electronic Publication: 2024 Mar 19.
Typ publikacji:
Journal Article
MeSH Terms:
Neuroprotective Agents*/pharmacology
Neuroprotective Agents*/therapeutic use
Brain Ischemia*/drug therapy
Brain Ischemia*/metabolism
Reperfusion Injury*/drug therapy
Reperfusion Injury*/metabolism
Iridoid Glucosides*
Animals ; NF-kappa B/metabolism ; NF-KappaB Inhibitor alpha/metabolism ; Gerbillinae/metabolism ; Tumor Necrosis Factor-alpha/metabolism ; Toll-Like Receptor 4/metabolism ; Gliosis ; Signal Transduction ; Ischemia ; Cerebral Infarction
Czasopismo naukowe
Tytuł:
LRP1 and RAGE Genes Transporting Amyloid and Tau Protein in the Hippocampal CA3 Area in an Ischemic Model of Alzheimer's Disease with 2-Year Survival.
Autorzy:
Pluta R; Department of Pathophysiology, Medical University of Lublin, 20-090 Lublin, Poland.
Kocki J; Department of Clinical Genetics, Medical University of Lublin, 20-080 Lublin, Poland.
Bogucki J; Department of Organic Chemistry, Faculty of Pharmacy, Medical University of Lublin, 20-093 Lublin, Poland.
Bogucka-Kocka A; Department of Biology and Genetics, Medical University of Lublin, 20-093 Lublin, Poland.
Czuczwar SJ; Department of Pathophysiology, Medical University of Lublin, 20-090 Lublin, Poland.
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Źródło:
Cells [Cells] 2023 Dec 04; Vol. 12 (23). Date of Electronic Publication: 2023 Dec 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Alzheimer Disease*/genetics
Alzheimer Disease*/metabolism
Brain Ischemia*/genetics
Brain Ischemia*/metabolism
Humans ; Amyloidogenic Proteins/metabolism ; Hippocampus/metabolism ; Ischemia/metabolism ; Low Density Lipoprotein Receptor-Related Protein-1/genetics ; Low Density Lipoprotein Receptor-Related Protein-1/metabolism ; tau Proteins/metabolism ; Protein Transport
Czasopismo naukowe
Tytuł:
URB447 Is Neuroprotective in Both Male and Female Rats after Neonatal Hypoxia-Ischemia and Enhances Neurogenesis in Females.
Autorzy:
Beldarrain G; Department of Cell Biology and Histology, School of Medicine and Nursing, University of the Basque Country (UPV/EHU), 48940 Leioa, Spain.
Chillida M; Department of Cell Biology and Histology, School of Medicine and Nursing, University of the Basque Country (UPV/EHU), 48940 Leioa, Spain.
Hilario E; Department of Cell Biology and Histology, School of Medicine and Nursing, University of the Basque Country (UPV/EHU), 48940 Leioa, Spain.
Herrero de la Parte B; Department of Surgery and Radiology and Physical Medicine, Faculty of Medicine and Nursing, University of the Basque Country (UPV/EHU), 48940 Leioa, Spain.
Álvarez A; Department of Cell Biology and Histology, School of Medicine and Nursing, University of the Basque Country (UPV/EHU), 48940 Leioa, Spain.
Alonso-Alconada D; Department of Cell Biology and Histology, School of Medicine and Nursing, University of the Basque Country (UPV/EHU), 48940 Leioa, Spain.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 28; Vol. 25 (3). Date of Electronic Publication: 2024 Jan 28.
Typ publikacji:
Journal Article
MeSH Terms:
Hypoxia-Ischemia, Brain*/pathology
Neuroprotective Agents*/pharmacology
Neuroprotective Agents*/therapeutic use
Cannabinoids*/pharmacology
Brain Injuries*/pathology
Benzyl Compounds*
Pyrroles*
Animals ; Rats ; Male ; Female ; Animals, Newborn ; Rats, Wistar ; Ischemia/pathology ; Neurogenesis ; Brain/pathology
Czasopismo naukowe
Tytuł:
Cardioprotective Effect against Ischemia-Reperfusion Injury of PAK-200, a Dihydropyridine Analog with an Inhibitory Effect on Cl Current.
Autorzy:
Namekata I; Department of Pharmacology, Faculty of Pharmaceutical Sciences, Toho University, 2-2-1 Miyama Funabashi, Chiba 274-8510, Japan.
Tamura M; Department of Pharmacology, Faculty of Pharmaceutical Sciences, Toho University, 2-2-1 Miyama Funabashi, Chiba 274-8510, Japan.
Kase J; Department of Pharmacology, Faculty of Pharmaceutical Sciences, Toho University, 2-2-1 Miyama Funabashi, Chiba 274-8510, Japan.
Hamaguchi S; Department of Pharmacology, Faculty of Pharmaceutical Sciences, Toho University, 2-2-1 Miyama Funabashi, Chiba 274-8510, Japan.
Tanaka H; Department of Pharmacology, Faculty of Pharmaceutical Sciences, Toho University, 2-2-1 Miyama Funabashi, Chiba 274-8510, Japan.
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Źródło:
Biomolecules [Biomolecules] 2023 Nov 29; Vol. 13 (12). Date of Electronic Publication: 2023 Nov 29.
Typ publikacji:
Journal Article
MeSH Terms:
Myocardial Ischemia*
Myocardial Reperfusion Injury*/drug therapy
Dihydropyridines*/pharmacology
Animals ; Guinea Pigs ; Isoproterenol/pharmacology ; Chlorides/pharmacology ; Ischemia ; Myocytes, Cardiac ; Myocardial Contraction
Czasopismo naukowe
Tytuł:
Homer1 Protects against Retinal Ganglion Cell Pyroptosis by Inhibiting Endoplasmic Reticulum Stress-Associated TXNIP/NLRP3 Inflammasome Activation after Middle Cerebral Artery Occlusion-Induced Retinal Ischemia.
Autorzy:
Lv W; Department of Neurosurgery, Xijing Hospital, Air Force Medical University, No. 127, Changle West Road, Xincheng District, Xi'an 710032, China.
Wu X; Department of Neurosurgery, Xijing Hospital, Air Force Medical University, No. 127, Changle West Road, Xincheng District, Xi'an 710032, China.
Dou Y; Department of Neurosurgery, Xijing Hospital, Air Force Medical University, No. 127, Changle West Road, Xincheng District, Xi'an 710032, China.
Yan Y; Department of Neurosurgery, Xijing Hospital, Air Force Medical University, No. 127, Changle West Road, Xincheng District, Xi'an 710032, China.
Chen L; Department of Ophthalmology, Xijing Hospital, Air Force Medical University, No. 127, Changle West Road, Xincheng District, Xi'an 710032, China.
Fei Z; Department of Neurosurgery, Xijing Hospital, Air Force Medical University, No. 127, Changle West Road, Xincheng District, Xi'an 710032, China.
Fei F; Department of Ophthalmology, Xijing Hospital, Air Force Medical University, No. 127, Changle West Road, Xincheng District, Xi'an 710032, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Nov 27; Vol. 24 (23). Date of Electronic Publication: 2023 Nov 27.
Typ publikacji:
Journal Article
MeSH Terms:
Brain Ischemia*/metabolism
Reperfusion Injury*/metabolism
Retinal Diseases*/etiology
Retinal Diseases*/metabolism
Animals ; Mice ; Endoplasmic Reticulum Stress ; Homer Scaffolding Proteins/metabolism ; Infarction, Middle Cerebral Artery/complications ; Infarction, Middle Cerebral Artery/metabolism ; Inflammasomes/metabolism ; Inflammation/metabolism ; Ischemia/metabolism ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; Pyroptosis ; Retinal Ganglion Cells/metabolism
Czasopismo naukowe
Tytuł:
Is Intrinsic Cardioprotection a Laboratory Phenomenon or a Clinically Relevant Tool to Salvage the Failing Heart?
Autorzy:
Ravingerova T; Institute for Heart Research, Centre of Experimental Medicine, Slovak Academy of Sciences, 9 Dubravska cesta, 841 04 Bratislava, Slovakia.
Adameova A; Institute for Heart Research, Centre of Experimental Medicine, Slovak Academy of Sciences, 9 Dubravska cesta, 841 04 Bratislava, Slovakia.; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Comenius University in Bratislava, 10 Odbojárov St., 832 32 Bratislava, Slovakia.
Lonek L; Institute for Heart Research, Centre of Experimental Medicine, Slovak Academy of Sciences, 9 Dubravska cesta, 841 04 Bratislava, Slovakia.
Farkasova V; Institute for Heart Research, Centre of Experimental Medicine, Slovak Academy of Sciences, 9 Dubravska cesta, 841 04 Bratislava, Slovakia.
Ferko M; Institute for Heart Research, Centre of Experimental Medicine, Slovak Academy of Sciences, 9 Dubravska cesta, 841 04 Bratislava, Slovakia.
Andelova N; Institute for Heart Research, Centre of Experimental Medicine, Slovak Academy of Sciences, 9 Dubravska cesta, 841 04 Bratislava, Slovakia.
Kura B; Institute for Heart Research, Centre of Experimental Medicine, Slovak Academy of Sciences, 9 Dubravska cesta, 841 04 Bratislava, Slovakia.
Slezak J; Institute for Heart Research, Centre of Experimental Medicine, Slovak Academy of Sciences, 9 Dubravska cesta, 841 04 Bratislava, Slovakia.
Galatou E; School of Biology, Aristotle University of Thessaloniki, 541 24 Thessaloniki, Greece.; Department of Life and Health Sciences, University of Nicosia, 2417 Nicosia, Cyprus.
Lazou A; School of Biology, Aristotle University of Thessaloniki, 541 24 Thessaloniki, Greece.
Zohdi V; Department of Anatomy, Faculty of Medicine, Comenius University in Bratislava, 24 Špitalska, 813 72 Bratislava, Slovakia.; Department of Anatomy and Developmental Biology, Monash Biomedicine Discovery Institute, Monash University, 19 Innovation Walk, Clayton, VIC 3800, Australia.
Dhalla NS; Institute of Cardiovascular Sciences St. Boniface Hospital Albrechtsen Research Centre, 351 Tache Avenue, Winnipeg, MB R2H 2A6, Canada.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Nov 18; Vol. 24 (22). Date of Electronic Publication: 2023 Nov 18.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Ischemic Preconditioning, Myocardial*/methods
Myocardial Ischemia*
Myocardial Infarction*
Heart Failure*/therapy
Male ; Humans ; Aged ; Heart ; Ischemia
Czasopismo naukowe
Tytuł:
High Doses of ANA12 Improve Phenobarbital Efficacy in a Model of Neonatal Post-Ischemic Seizures.
Autorzy:
Vyas P; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Chaturvedi I; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Hwang Y; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Scafidi J; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.; Department of Neurology and Developmental Medicine, Kennedy Krieger Institute, Baltimore, MD 21205, USA.
Kadam SD; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.; Department of Neurology and Developmental Medicine, Kennedy Krieger Institute, Baltimore, MD 21205, USA.; Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Stafstrom CE; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 24; Vol. 25 (3). Date of Electronic Publication: 2024 Jan 24.
Typ publikacji:
Journal Article
MeSH Terms:
Epilepsy*/drug therapy
Hypoxia-Ischemia, Brain*/drug therapy
Animals ; Mice ; Anticonvulsants/pharmacology ; Anticonvulsants/therapeutic use ; Animals, Newborn ; Disease Models, Animal ; Seizures/drug therapy ; Seizures/etiology ; Seizures/metabolism ; Phenobarbital/pharmacology ; Phenobarbital/therapeutic use ; Ischemia/drug therapy
Czasopismo naukowe
Tytuł:
Neuroadaptive Biochemical Mechanisms of Remote Ischemic Conditioning.
Autorzy:
Baranova K; I. P. Pavlov Institute of Physiology, Russian Academy of Sciences, 199034 Saint Petersburg, Russia.
Nalivaeva N; I. P. Pavlov Institute of Physiology, Russian Academy of Sciences, 199034 Saint Petersburg, Russia.
Rybnikova E; I. P. Pavlov Institute of Physiology, Russian Academy of Sciences, 199034 Saint Petersburg, Russia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Dec 01; Vol. 24 (23). Date of Electronic Publication: 2023 Dec 01.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Brain Ischemia*/metabolism
Brain Injuries*
Ischemic Postconditioning*
Humans ; Ischemia ; Hippocampus/metabolism ; Antioxidants
Czasopismo naukowe
Tytuł:
Postischemic Infusion of Apigenin Reduces Seizure Burden in Preterm Fetal Sheep.
Autorzy:
Cho KHT; Department of Physiology, University of Auckland, Auckland 1142, New Zealand.
Hounsell N; Department of Physiology, University of Auckland, Auckland 1142, New Zealand.
McClendon E; Department of Pediatrics, Oregon Health & Science University, Portland, OR 97239, USA.
Riddle A; Department of Pediatrics, Oregon Health & Science University, Portland, OR 97239, USA.
Basappa; Laboratory of Chemical Biology, Department of Studies in Organic Chemistry, University of Mysore, Manasagangotri, Mysore 570006, India.
Dhillon SK; Department of Physiology, University of Auckland, Auckland 1142, New Zealand.
Bennet L; Department of Physiology, University of Auckland, Auckland 1142, New Zealand.
Back S; Department of Pediatrics, Oregon Health & Science University, Portland, OR 97239, USA.; Department of Neurology, Oregon Health & Science University, Portland, OR 97239, USA.
Sherman LS; Division of Neuroscience, Oregon National Primate Research Center, Beaverton, OR 97006, USA.; Department of Cell, Developmental and Cancer Biology, Oregon Health & Science University, Portland, OR 97239, USA.
Gunn AJ; Department of Physiology, University of Auckland, Auckland 1142, New Zealand.
Dean JM; Department of Physiology, University of Auckland, Auckland 1142, New Zealand.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Nov 29; Vol. 24 (23). Date of Electronic Publication: 2023 Nov 29.
Typ publikacji:
Journal Article
MeSH Terms:
Apigenin*/pharmacology
Apigenin*/therapeutic use
Hypoxia-Ischemia, Brain*/pathology
Pregnancy ; Female ; Sheep ; Animals ; Hyaluronoglucosaminidase ; Pilot Projects ; Seizures/drug therapy ; Fetus/pathology ; Ischemia ; Electroencephalography
Czasopismo naukowe
Tytuł:
Complement C3 Reduces Apoptosis via Interaction with the Intrinsic Apoptotic Pathway.
Autorzy:
Fang Z; Departments of Anesthesiology, SUNY Downstate Health Science University, 450 Clarkson Avenue, Brooklyn, NY 11203, USA.
Lee H; Departments of Anesthesiology, SUNY Downstate Health Science University, 450 Clarkson Avenue, Brooklyn, NY 11203, USA.
Liu J; Departments of Anesthesiology, SUNY Downstate Health Science University, 450 Clarkson Avenue, Brooklyn, NY 11203, USA.
Wong KA; Departments of Anesthesiology, SUNY Downstate Health Science University, 450 Clarkson Avenue, Brooklyn, NY 11203, USA.
Brown LM; Quantitative Proteomics and Metabolomics Center, Department of Biological Sciences, Columbia University, New York, NY 10027, USA.
Li X; Departments of Anesthesiology, SUNY Downstate Health Science University, 450 Clarkson Avenue, Brooklyn, NY 11203, USA.
Xiaoli AM; Department of Medicine/Endocrinology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Yang F; Department of Medicine/Endocrinology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Zhang M; Departments of Anesthesiology, SUNY Downstate Health Science University, 450 Clarkson Avenue, Brooklyn, NY 11203, USA.; Departments of Cell Biology, SUNY Downstate Health Science University, 450 Clarkson Avenue, Brooklyn, NY 11203, USA.
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Źródło:
Cells [Cells] 2023 Sep 15; Vol. 12 (18). Date of Electronic Publication: 2023 Sep 15.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Myocardial Reperfusion Injury*/metabolism
Myocardial Ischemia*/metabolism
Mice ; Humans ; Animals ; Complement C3/metabolism ; Complement C3/pharmacology ; Apoptosis ; Myocardium/metabolism ; Myocytes, Cardiac/metabolism ; Ischemia/metabolism
Czasopismo naukowe
Tytuł:
Hypothermic Protection in Neocortex Is Topographic and Laminar, Seizure Unmitigating, and Partially Rescues Neurons Depleted of RNA Splicing Protein Rbfox3/NeuN in Neonatal Hypoxic-Ischemic Male Piglets.
Autorzy:
Primiani CT; Department of Neurology, Johns Hopkins University School of Medicine, 558 Ross Building, 720 Rutland Avenue, Baltimore, MD 21205-2196, USA.
Lee JK; Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, 558 Ross Building, 720 Rutland Avenue, Baltimore, MD 21205-2196, USA.
O'Brien CE; Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, 558 Ross Building, 720 Rutland Avenue, Baltimore, MD 21205-2196, USA.
Chen MW; Department Pediatrics, Johns Hopkins University School of Medicine, 558 Ross Building, 720 Rutland Avenue, Baltimore, MD 21205-2196, USA.
Perin J; Department of Biostatistics and Epidemiology, Johns Hopkins University School of Medicine, 558 Ross Building, 720 Rutland Avenue, Baltimore, MD 21205-2196, USA.
Kulikowicz E; Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, 558 Ross Building, 720 Rutland Avenue, Baltimore, MD 21205-2196, USA.
Santos P; Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, 558 Ross Building, 720 Rutland Avenue, Baltimore, MD 21205-2196, USA.
Adams S; Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, 558 Ross Building, 720 Rutland Avenue, Baltimore, MD 21205-2196, USA.
Lester B; Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, 558 Ross Building, 720 Rutland Avenue, Baltimore, MD 21205-2196, USA.
Rivera-Diaz N; Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, 558 Ross Building, 720 Rutland Avenue, Baltimore, MD 21205-2196, USA.
Olberding V; Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, 558 Ross Building, 720 Rutland Avenue, Baltimore, MD 21205-2196, USA.
Niedzwiecki MV; Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, 558 Ross Building, 720 Rutland Avenue, Baltimore, MD 21205-2196, USA.
Ritzl EK; Department of Neurology, Johns Hopkins University School of Medicine, 558 Ross Building, 720 Rutland Avenue, Baltimore, MD 21205-2196, USA.
Habela CW; Department of Neurology, Johns Hopkins University School of Medicine, 558 Ross Building, 720 Rutland Avenue, Baltimore, MD 21205-2196, USA.
Liu X; Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, 558 Ross Building, 720 Rutland Avenue, Baltimore, MD 21205-2196, USA.
Yang ZJ; Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, 558 Ross Building, 720 Rutland Avenue, Baltimore, MD 21205-2196, USA.
Koehler RC; Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, 558 Ross Building, 720 Rutland Avenue, Baltimore, MD 21205-2196, USA.
Martin LJ; Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, 558 Ross Building, 720 Rutland Avenue, Baltimore, MD 21205-2196, USA.; Department of Pathology, Johns Hopkins University School of Medicine, 558 Ross Building, 720 Rutland Avenue, Baltimore, MD 21205-2196, USA.; Department of Neuroscience, Johns Hopkins University School of Medicine, 558 Ross Building, 720 Rutland Avenue, Baltimore, MD 21205-2196, USA.; The Pathobiology Graduate Training Program, Johns Hopkins University School of Medicine, 558 Ross Building, 720 Rutland Avenue, Baltimore, MD 21205-2196, USA.
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Źródło:
Cells [Cells] 2023 Oct 15; Vol. 12 (20). Date of Electronic Publication: 2023 Oct 15.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Hypothermia*/pathology
Neocortex*/metabolism
Hypoxia-Ischemia, Brain*/pathology
Animals ; Male ; Swine ; Animals, Newborn ; Hypoxia/pathology ; Neurons/metabolism ; Ischemia/pathology ; Seizures
Czasopismo naukowe
Tytuł:
Tricellulin, α-Catenin and Microfibrillar-Associated Protein 5 Exhibit Concomitantly Altered Immunosignals along with Vascular, Extracellular and Cytoskeletal Elements after Experimental Focal Cerebral Ischemia.
Autorzy:
Höfling C; Paul Flechsig Institute for Brain Research, University of Leipzig, Liebigstr. 19, 04103 Leipzig, Germany.
Roßner S; Paul Flechsig Institute for Brain Research, University of Leipzig, Liebigstr. 19, 04103 Leipzig, Germany.
Flachmeyer B; Institute of Anatomy, University of Leipzig, Liebigstr. 13, 04103 Leipzig, Germany.
Krueger M; Institute of Anatomy, University of Leipzig, Liebigstr. 13, 04103 Leipzig, Germany.
Härtig W; Paul Flechsig Institute for Brain Research, University of Leipzig, Liebigstr. 19, 04103 Leipzig, Germany.
Michalski D; Department of Neurology, University of Leipzig, Liebigstr. 20, 04103 Leipzig, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jul 25; Vol. 24 (15). Date of Electronic Publication: 2023 Jul 25.
Typ publikacji:
Journal Article
MeSH Terms:
Brain Ischemia*/metabolism
Stroke*/metabolism
Animals ; Mice ; Rats ; alpha Catenin ; Cerebral Infarction ; Cytoskeleton/metabolism ; Ischemia ; MARVEL Domain Containing 2 Protein ; Intercellular Signaling Peptides and Proteins ; Contractile Proteins
Czasopismo naukowe
Tytuł:
A Comparative Analysis of Neuroprotective Properties of Taxifolin and Its Water-Soluble Form in Ischemia of Cerebral Cortical Cells of the Mouse.
Autorzy:
Varlamova EG; Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino 142290, Russia.
Uspalenko NI; Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino 142290, Russia.
Khmil NV; Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino 142290, Russia.
Shigaeva MI; Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino 142290, Russia.
Stepanov MR; Advanced Technologies Ltd., Moscow 119333, Russia.
Ananyan MA; Advanced Technologies Ltd., Moscow 119333, Russia.
Timchenko MA; Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino 142290, Russia.
Molchanov MV; Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino 142290, Russia.
Mironova GD; Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino 142290, Russia.
Turovsky EA; Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino 142290, Russia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jul 14; Vol. 24 (14). Date of Electronic Publication: 2023 Jul 14.
Typ publikacji:
Journal Article
MeSH Terms:
Brain Ischemia*/drug therapy
Brain Ischemia*/metabolism
Neuroprotective Agents*/pharmacology
Neuroprotective Agents*/metabolism
Mice ; Animals ; Signal Transduction ; Quercetin/pharmacology ; Quercetin/metabolism ; Neurons/metabolism ; Oxygen/metabolism ; Glucose/metabolism ; Cells, Cultured ; Ischemia/metabolism ; Cell Survival
Czasopismo naukowe
Tytuł:
Hypoxic-Ischemic Brain Injury in ECMO: Pathophysiology, Neuromonitoring, and Therapeutic Opportunities.
Autorzy:
Khanduja S; Division of Cardiac Surgery, Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
Kim J; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Kang JK; Division of Cardiac Surgery, Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
Feng CY; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Vogelsong MA; Department of Anesthesiology, Perioperative & Pain Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.
Geocadin RG; Divisions of Neurosciences Critical Care, Departments of Neurology, Surgery, Anesthesiology and Critical Care Medicine and Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Whitman G; Division of Cardiac Surgery, Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
Cho SM; Division of Cardiac Surgery, Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; Divisions of Neurosciences Critical Care, Departments of Neurology, Surgery, Anesthesiology and Critical Care Medicine and Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
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Źródło:
Cells [Cells] 2023 Jun 05; Vol. 12 (11). Date of Electronic Publication: 2023 Jun 05.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Extracorporeal Membrane Oxygenation*/adverse effects
Extracorporeal Membrane Oxygenation*/methods
Hypoxia-Ischemia, Brain*/complications
Brain Injuries*/etiology
Humans ; Perfusion ; Ischemia
Czasopismo naukowe
Tytuł:
Inter-Alpha Inhibitor Proteins Modify the Microvasculature after Exposure to Hypoxia-Ischemia and Hypoxia in Neonatal Rats.
Autorzy:
Girolamo F; Department of Translational Biomedicines and Neuroscience (DiBraiN), University of Bari School of Medicine, 70124 Bari, Italy.
Lim YP; ProThera Biologics, Inc., Providence, RI 02905, USA.; Department of Pathology and Laboratory Medicine, Alpert Medical School of Brown University, Providence, RI 02905, USA.
Virgintino D; Department of Translational Biomedicines and Neuroscience (DiBraiN), University of Bari School of Medicine, 70124 Bari, Italy.
Stonestreet BS; Women & Infants Hospital of Rhode Island, Alpert Medical School of Brown University, Providence, RI 02905, USA.
Chen XF; Women & Infants Hospital of Rhode Island, Alpert Medical School of Brown University, Providence, RI 02905, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Apr 04; Vol. 24 (7). Date of Electronic Publication: 2023 Apr 04.
Typ publikacji:
Journal Article
MeSH Terms:
Hypoxia-Ischemia, Brain*/metabolism
Brain Injuries*
Female ; Rats ; Animals ; Humans ; Animals, Newborn ; Laminin/metabolism ; Hypoxia/metabolism ; Brain/metabolism ; Ischemia ; Microvessels/metabolism
Czasopismo naukowe
Tytuł:
Wireless Single-Lead versus Standard 12-Lead ECG, for ST-Segment Deviation during Adenosine Cardiac Stress Scintigraphy.
Autorzy:
Fabricius Ekenberg L; Department of Anesthesiology, Centre for Cancer and Organ Diseases, Rigshospitalet Copenhagen University Hospital, Blegdamsvej 9, 2200 Copenhagen, Denmark.
Høfsten DE; Department of Cardiology, Rigshospitalet Copenhagen University Hospital, 2100 Copenhagen, Denmark.
Rasmussen SM; Biomedical Signal Processing & AI Research Group, Digital Health Section, Department of Health Technology, Technical University of Denmark, 2800 Kgs. Lyngby, Denmark.
Mølgaard J; Department of Anesthesiology, Centre for Cancer and Organ Diseases, Rigshospitalet Copenhagen University Hospital, Blegdamsvej 9, 2200 Copenhagen, Denmark.
Hasbak P; Department of Clinical Physiological and Nuclear Medicine, Center for Diagnostics, Rigshospitalet Copenhagen University Hospital, 2100 Copenhagen, Denmark.
Sørensen HBD; Biomedical Signal Processing & AI Research Group, Digital Health Section, Department of Health Technology, Technical University of Denmark, 2800 Kgs. Lyngby, Denmark.
Meyhoff CS; Department of Anaesthesia and Intensive Care, Copenhagen University Hospital-Bispebjerg and Frederiksberg Hospital, 2400 Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, 2200 Copenhagen, Denmark.
Aasvang EK; Department of Anesthesiology, Centre for Cancer and Organ Diseases, Rigshospitalet Copenhagen University Hospital, Blegdamsvej 9, 2200 Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, 2200 Copenhagen, Denmark.
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Źródło:
Sensors (Basel, Switzerland) [Sensors (Basel)] 2023 Mar 09; Vol. 23 (6). Date of Electronic Publication: 2023 Mar 09.
Typ publikacji:
Journal Article
MeSH Terms:
Myocardial Ischemia*/diagnostic imaging
Coronary Artery Disease*
Humans ; Electrocardiography/methods ; Radionuclide Imaging ; Arrhythmias, Cardiac ; Ischemia
Czasopismo naukowe
Tytuł:
Therapeutic Hypothermia Attenuates Cortical Interneuron Loss after Cerebral Ischemia in Near-Term Fetal Sheep.
Autorzy:
Yang P; Department of Physiology, Faculty of Medical and Health Sciences, University of Auckland, Auckland 1023, New Zealand.
Davidson JO; Department of Physiology, Faculty of Medical and Health Sciences, University of Auckland, Auckland 1023, New Zealand.
Zhou KQ; Department of Physiology, Faculty of Medical and Health Sciences, University of Auckland, Auckland 1023, New Zealand.
Wilson R; Department of Physiology, Faculty of Medical and Health Sciences, University of Auckland, Auckland 1023, New Zealand.
Wassink G; Department of Physiology, Faculty of Medical and Health Sciences, University of Auckland, Auckland 1023, New Zealand.
Prasad JD; Department of Physiology, Faculty of Medical and Health Sciences, University of Auckland, Auckland 1023, New Zealand.
Bennet L; Department of Physiology, Faculty of Medical and Health Sciences, University of Auckland, Auckland 1023, New Zealand.
Gunn AJ; Department of Physiology, Faculty of Medical and Health Sciences, University of Auckland, Auckland 1023, New Zealand.
Dean JM; Department of Physiology, Faculty of Medical and Health Sciences, University of Auckland, Auckland 1023, New Zealand.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Feb 12; Vol. 24 (4). Date of Electronic Publication: 2023 Feb 12.
Typ publikacji:
Journal Article
MeSH Terms:
Cerebral Infarction*/pathology
Cerebral Infarction*/therapy
Hypothermia, Induced*/methods
Hypoxia-Ischemia, Brain*/pathology
Animals ; Interneurons/pathology ; Ischemia/pathology ; Ischemia/therapy ; Parvalbumins ; Sheep
Czasopismo naukowe
Tytuł:
The Roles of Bone Marrow-Derived Stem Cells in Coronary Collateral Growth Induced by Repetitive Ischemia.
Autorzy:
Enrick M; Department of Integrative Medical Sciences, Northeast Ohio Medical University, Rootstown, OH 44272, USA.
Jamaiyar A; Department of Integrative Medical Sciences, Northeast Ohio Medical University, Rootstown, OH 44272, USA.
Ohanyan V; Department of Integrative Medical Sciences, Northeast Ohio Medical University, Rootstown, OH 44272, USA.
Juguilon C; Department of Integrative Medical Sciences, Northeast Ohio Medical University, Rootstown, OH 44272, USA.
Kolz C; Department of Integrative Medical Sciences, Northeast Ohio Medical University, Rootstown, OH 44272, USA.
Shi X; Department of Integrative Medical Sciences, Northeast Ohio Medical University, Rootstown, OH 44272, USA.
Janota D; Department of Integrative Medical Sciences, Northeast Ohio Medical University, Rootstown, OH 44272, USA.
Wan W; Department of Integrative Medical Sciences, Northeast Ohio Medical University, Rootstown, OH 44272, USA.
Richardson D; Department of Integrative Medical Sciences, Northeast Ohio Medical University, Rootstown, OH 44272, USA.
Stevanov K; Department of Integrative Medical Sciences, Northeast Ohio Medical University, Rootstown, OH 44272, USA.
Hakobyan T; Department of Integrative Medical Sciences, Northeast Ohio Medical University, Rootstown, OH 44272, USA.
Shockling L; Department of Integrative Medical Sciences, Northeast Ohio Medical University, Rootstown, OH 44272, USA.
Diaz A; Department of Integrative Medical Sciences, Northeast Ohio Medical University, Rootstown, OH 44272, USA.
Usip S; Department of Anatomy and Neuroscience, Northeast Ohio Medical University, Rootstown, OH 44272, USA.
Dong F; Department of Integrative Medical Sciences, Northeast Ohio Medical University, Rootstown, OH 44272, USA.
Zhang P; Department of Integrative Medical Sciences, Northeast Ohio Medical University, Rootstown, OH 44272, USA.
Chilian WM; Department of Integrative Medical Sciences, Northeast Ohio Medical University, Rootstown, OH 44272, USA.
Yin L; Department of Integrative Medical Sciences, Northeast Ohio Medical University, Rootstown, OH 44272, USA.
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Źródło:
Cells [Cells] 2023 Jan 06; Vol. 12 (2). Date of Electronic Publication: 2023 Jan 06.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Collateral Circulation*/physiology
Myocardial Ischemia*/therapy
Rats ; Animals ; Bone Marrow ; Endothelial Cells ; Ischemia ; Stem Cells
Czasopismo naukowe
Tytuł:
Hypothermia Does Not Boost the Neuroprotection Promoted by Umbilical Cord Blood Cells in a Neonatal Hypoxia-Ischemia Rat Model.
Autorzy:
Serrenho I; Health Sciences Research Center (CICS-UBI), University of Beira Interior, 6201-506 Covilhã, Portugal.; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Cardoso CM; Crioestaminal (Stemlab S.A.), 3060-197 Cantanhede, Portugal.
Grãos M; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.; Biocant, Technology Transfer Association, 3060-197 Cantanhede, Portugal.; Institute for Interdisciplinary Research, University of Coimbra (IIIUC), 3030-789 Coimbra, Portugal.
Dinis A; Pediatric Intensive Care Unit, Hospital Pediátrico, Centro Hospitalar e Universitário de Coimbra, 3004-561 Coimbra, Portugal.
Manadas B; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.; Institute for Interdisciplinary Research, University of Coimbra (IIIUC), 3030-789 Coimbra, Portugal.
Baltazar G; Health Sciences Research Center (CICS-UBI), University of Beira Interior, 6201-506 Covilhã, Portugal.; Faculty of Health Sciences, University of Beira Interior, 6201-506 Covilhã, Portugal.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Dec 23; Vol. 24 (1). Date of Electronic Publication: 2022 Dec 23.
Typ publikacji:
Journal Article
MeSH Terms:
Hypothermia*
Hypoxia-Ischemia, Brain*/therapy
Hypoxia-Ischemia, Brain*/pathology
Hypothermia, Induced*
Rats ; Animals ; Neuroprotection ; Fetal Blood ; Ischemia/therapy
Czasopismo naukowe
Tytuł:
Choline Improves Neonatal Hypoxia-Ischemia Induced Changes in Male but Not Female Rats.
Autorzy:
Adeyemo T; Department of Pediatrics, University of Maryland School of Medicine, 655 W. Baltimore St., Baltimore, MD 21201, USA.
Jaiyesimi A; Department of Pediatrics, University of Maryland School of Medicine, 655 W. Baltimore St., Baltimore, MD 21201, USA.
Bumgardner JG; Department of Pediatrics, University of Maryland School of Medicine, 655 W. Baltimore St., Baltimore, MD 21201, USA.
Lohr C; Department of Pediatrics, University of Maryland School of Medicine, 655 W. Baltimore St., Baltimore, MD 21201, USA.
Banerjee A; Department of Pediatrics, University of Maryland School of Medicine, 655 W. Baltimore St., Baltimore, MD 21201, USA.
McKenna MC; Department of Pediatrics, University of Maryland School of Medicine, 655 W. Baltimore St., Baltimore, MD 21201, USA.; Program in Neuroscience, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Waddell J; Department of Pediatrics, University of Maryland School of Medicine, 655 W. Baltimore St., Baltimore, MD 21201, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Nov 12; Vol. 23 (22). Date of Electronic Publication: 2022 Nov 12.
Typ publikacji:
Journal Article
MeSH Terms:
Choline*/pharmacology
Hypoxia-Ischemia, Brain*/pathology
Female ; Animals ; Rats ; Male ; Animals, Newborn ; Ischemia
Czasopismo naukowe

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