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Title:
Reducing agalsidase beta infusion time in Fabry patients: low incidence of antibody formation and infusion-associated reactions in an Italian multicenter study.
Authors:
Mignani R; Nephrology, Dialysis and Transplantation, IRCCS S. Orsola Hospital, University of Bologna, Bologna, Italy. .
Americo C; Nephrology and Dialysis Unit, Pierantoni Hospital, Forlì, Italy.
Aucella F; Nephrology Unit, Ospedale Casa Sollievo della Sofferenza, San Giovanni Rotondo, Foggia, Italy.
Battaglia Y; Nephrology and Dialysis Unit, St. Anna University Hospital, Ferrara, Italy.
Cianci V; Regional Epilepsy Centre, Great Metropolitan Hospital, Reggio Calabria, Italy.
Sapuppo A; Pediatric Clinic, Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy.
Lanzillo C; Division of Cardiology, Policlinico Casilino, Rome, Italy.
Pennacchiotti F; Nephrology Unit, Manduria Hospital, Taranto, Italy.
Tartaglia L; Nephrology Dialysis and Transplantation Unit, Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy.
Marchi G; MetabERN Referral Center for Lysosomal Storage Disorders, Internal Medicine Unit, University of Verona, Verona, Italy.
Pieruzzi F; Clinical Nephrology, School of Medicine and Surgery, University of Milano, Bicocca, Italy.; Nephrology and Dialysis Unit, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy.
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Source:
Orphanet journal of rare diseases [Orphanet J Rare Dis] 2024 Feb 02; Vol. 19 (1), pp. 38. Date of Electronic Publication: 2024 Feb 02.
Publication Type:
Multicenter Study; Journal Article
MeSH Terms:
alpha-Galactosidase*/therapeutic use
Fabry Disease*
Isoenzymes*
Humans ; Quality of Life ; Antibody Formation ; Incidence ; Treatment Outcome ; Antibodies/therapeutic use ; Recombinant Proteins/therapeutic use ; Enzyme Replacement Therapy/methods ; Italy
Academic Journal
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Title:
Role of Conformational Dynamics of Sulfotransferases SULT1A1 and SULT1A3 in Substrate Specificity.
Authors:
Toth D; CiTCoM UMR 8038 CNRS, INSERM U1268 MCTR, Université Paris Cité, 75006 Paris, France.; Department of Biophysics and Radiation Biology, Semmelweis University, 1094 Budapest, Hungary.
Dudas B; CiTCoM UMR 8038 CNRS, INSERM U1268 MCTR, Université Paris Cité, 75006 Paris, France.; Department of Physics and Astronomy, University College London, London WC1E 6BT, UK.
Miteva MA; CiTCoM UMR 8038 CNRS, INSERM U1268 MCTR, Université Paris Cité, 75006 Paris, France.
Balog E; Department of Biophysics and Radiation Biology, Semmelweis University, 1094 Budapest, Hungary.
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Source:
International journal of molecular sciences [Int J Mol Sci] 2023 Nov 29; Vol. 24 (23). Date of Electronic Publication: 2023 Nov 29.
Publication Type:
Journal Article
MeSH Terms:
Sulfotransferases*/metabolism
Isoenzymes*/metabolism
Humans ; Substrate Specificity ; Binding Sites ; Arylsulfotransferase/metabolism
Academic Journal
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Title:
Melatonin Activation by Human Cytochrome P450 Enzymes: A Comparison between Different Isozymes.
Authors:
Mokkawes T; Department of Chemical Engineering, Manchester Institute of Biotechnology, The University of Manchester, 131 Princess Street, Manchester M1 7DN, UK.
De Visser T; Department of Chemical Engineering, Manchester Institute of Biotechnology, The University of Manchester, 131 Princess Street, Manchester M1 7DN, UK.
Cao Y; Department of Chemical Engineering, Manchester Institute of Biotechnology, The University of Manchester, 131 Princess Street, Manchester M1 7DN, UK.
De Visser SP; Department of Chemical Engineering, Manchester Institute of Biotechnology, The University of Manchester, 131 Princess Street, Manchester M1 7DN, UK.
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Source:
Molecules (Basel, Switzerland) [Molecules] 2023 Oct 06; Vol. 28 (19). Date of Electronic Publication: 2023 Oct 06.
Publication Type:
Journal Article
MeSH Terms:
Isoenzymes*/metabolism
Melatonin*
Humans ; Cytochrome P-450 Enzyme System/metabolism ; Catalytic Domain ; Heme ; Cytochrome P-450 CYP1A2/metabolism
Academic Journal
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Title:
In Vitro Enzyme Kinetics and NMR-Based Product Elucidation for Glutathione S-Conjugation of the Anticancer Unsymmetrical Bisacridine C-2028 in Liver Microsomes and Cytosol: Major Role of Glutathione S-Transferase M1-1 Isoenzyme.
Authors:
Potęga A; Department of Pharmaceutical Technology and Biochemistry, Faculty of Chemistry, Gdańsk University of Technology, Gabriela Narutowicza Str. 11/12, 80-233 Gdańsk, Poland.
Rafalska D; Department of Pharmaceutical Technology and Biochemistry, Faculty of Chemistry, Gdańsk University of Technology, Gabriela Narutowicza Str. 11/12, 80-233 Gdańsk, Poland.
Kazimierczyk D; Department of Pharmaceutical Technology and Biochemistry, Faculty of Chemistry, Gdańsk University of Technology, Gabriela Narutowicza Str. 11/12, 80-233 Gdańsk, Poland.
Kosno M; Department of Pharmaceutical Technology and Biochemistry, Faculty of Chemistry, Gdańsk University of Technology, Gabriela Narutowicza Str. 11/12, 80-233 Gdańsk, Poland.
Pawłowicz A; Institute of Bioorganic Chemistry, Polish Academy of Sciences, Zygmunta Noskowskiego Str. 12/14, 61-704 Poznań, Poland.
Andrałojć W; Institute of Bioorganic Chemistry, Polish Academy of Sciences, Zygmunta Noskowskiego Str. 12/14, 61-704 Poznań, Poland.
Paluszkiewicz E; Department of Pharmaceutical Technology and Biochemistry, Faculty of Chemistry, Gdańsk University of Technology, Gabriela Narutowicza Str. 11/12, 80-233 Gdańsk, Poland.
Laskowski T; Department of Pharmaceutical Technology and Biochemistry, Faculty of Chemistry, Gdańsk University of Technology, Gabriela Narutowicza Str. 11/12, 80-233 Gdańsk, Poland.
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Source:
Molecules (Basel, Switzerland) [Molecules] 2023 Sep 26; Vol. 28 (19). Date of Electronic Publication: 2023 Sep 26.
Publication Type:
Journal Article
MeSH Terms:
Microsomes, Liver*/metabolism
Isoenzymes*/metabolism
Male ; Rats ; Humans ; Animals ; Cytosol/metabolism ; Glutathione Transferase/metabolism ; Liver/metabolism ; Magnetic Resonance Spectroscopy ; Glutathione/metabolism ; Kinetics
Academic Journal
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Title:
Persistent hypoxia promotes myofibroblast differentiation via GPR-81 and differential regulation of LDH isoenzymes in normal and idiopathic pulmonary fibrosis fibroblasts.
Authors:
Nho RS; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, The Davis Heart and Lung Research Institute, The Ohio State University, Columbus, Ohio, USA.
Rice C; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, The Davis Heart and Lung Research Institute, The Ohio State University, Columbus, Ohio, USA.
Prasad J; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, The Davis Heart and Lung Research Institute, The Ohio State University, Columbus, Ohio, USA.
Bone H; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, The Davis Heart and Lung Research Institute, The Ohio State University, Columbus, Ohio, USA.
Farkas L; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, The Davis Heart and Lung Research Institute, The Ohio State University, Columbus, Ohio, USA.
Rojas M; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, The Davis Heart and Lung Research Institute, The Ohio State University, Columbus, Ohio, USA.
Horowitz JC; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, The Davis Heart and Lung Research Institute, The Ohio State University, Columbus, Ohio, USA.
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Source:
Physiological reports [Physiol Rep] 2023 Sep; Vol. 11 (17), pp. e15759.
Publication Type:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Isoenzymes*
Idiopathic Pulmonary Fibrosis*
Humans ; Myofibroblasts ; L-Lactate Dehydrogenase ; Fibroblasts ; Lactic Acid ; Hypoxia ; Oxygen
Academic Journal
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Title:
Emerging Roles of Phospholipase C Beta Isozymes as Potential Biomarkers in Cardiac Disorders.
Authors:
Fazio A; Department of Biomedical and Neuromotor Sciences, University of Bologna, Via Irnerio 48, 40126 Bologna, Italy.
Evangelisti C; Department of Biomedical and Neuromotor Sciences, University of Bologna, Via Irnerio 48, 40126 Bologna, Italy.
Cappellini A; Department of Biomedical and Neuromotor Sciences, University of Bologna, Via Irnerio 48, 40126 Bologna, Italy.
Mongiorgi S; Department of Biomedical and Neuromotor Sciences, University of Bologna, Via Irnerio 48, 40126 Bologna, Italy.
Koufi FD; Department of Biomedical and Neuromotor Sciences, University of Bologna, Via Irnerio 48, 40126 Bologna, Italy.
Neri I; Department of Biomedical and Neuromotor Sciences, University of Bologna, Via Irnerio 48, 40126 Bologna, Italy.
Marvi MV; Department of Biomedical and Neuromotor Sciences, University of Bologna, Via Irnerio 48, 40126 Bologna, Italy.
Russo M; Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center 'Guido Tarone', University of Torino, 10126 Torino, Italy.
Ghigo A; Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center 'Guido Tarone', University of Torino, 10126 Torino, Italy.
Manzoli L; Department of Biomedical and Neuromotor Sciences, University of Bologna, Via Irnerio 48, 40126 Bologna, Italy.
Fiume R; Department of Biomedical and Neuromotor Sciences, University of Bologna, Via Irnerio 48, 40126 Bologna, Italy.
Ratti S; Department of Biomedical and Neuromotor Sciences, University of Bologna, Via Irnerio 48, 40126 Bologna, Italy.
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Source:
International journal of molecular sciences [Int J Mol Sci] 2023 Aug 23; Vol. 24 (17). Date of Electronic Publication: 2023 Aug 23.
Publication Type:
Journal Article; Review
MeSH Terms:
Isoenzymes*
Heart Diseases*
Animals ; Humans ; Phospholipase C beta ; Myocytes, Cardiac ; Biomarkers ; Mammals
Academic Journal
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Title:
Inhibitory Investigations of Acyl-CoA Derivatives against Human Lipoxygenase Isozymes.
Authors:
Tran M; Department of Chemistry and Biochemistry, University of California Santa Cruz, Santa Cruz, CA 95064, USA.
Yang K; Department of Chemistry and Biochemistry, University of California Santa Cruz, Santa Cruz, CA 95064, USA.
Glukhova A; Department of Biochemistry and Pharmacology, University of Melbourne, Melbourne, VIC 3010, Australia.; Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, VIC 3010, Australia.; Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC 3052, Australia.; ARC Centre for Cryo-Electron Microscopy of Membrane Proteins, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC 3052, Australia.
Holinstat M; Department of Pharmacology, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
Holman T; Department of Chemistry and Biochemistry, University of California Santa Cruz, Santa Cruz, CA 95064, USA.
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Source:
International journal of molecular sciences [Int J Mol Sci] 2023 Jun 30; Vol. 24 (13). Date of Electronic Publication: 2023 Jun 30.
Publication Type:
Journal Article
MeSH Terms:
Lipoxygenase*
Isoenzymes*
Humans ; Oxylipins ; Acyl Coenzyme A/metabolism ; Inflammation ; Scavenger Receptors, Class E
Academic Journal
Full Text  Link opens in a new window Full TextDetails
Title:
Computational Insights into Novel Inhibitor N -(3-( tert -Butylcarbamoyl)-4-methoxyphenyl)-indole and Ingliforib Specific against GP Isoenzyme Dimers Interaction Mechanism.
Authors:
Wang Y; Laboratory of Traditional Chinese Medicine Research and Development of Hebei Province, Institute of Traditional Chinese Medicine, Chengde Medical University, Chengde 067000, China.
Li S; Laboratory of Traditional Chinese Medicine Research and Development of Hebei Province, Institute of Traditional Chinese Medicine, Chengde Medical University, Chengde 067000, China.
Yan Z; Laboratory of Traditional Chinese Medicine Research and Development of Hebei Province, Institute of Traditional Chinese Medicine, Chengde Medical University, Chengde 067000, China.
Zhang L; Laboratory of Traditional Chinese Medicine Research and Development of Hebei Province, Institute of Traditional Chinese Medicine, Chengde Medical University, Chengde 067000, China.
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Source:
Molecules (Basel, Switzerland) [Molecules] 2023 Jun 22; Vol. 28 (13). Date of Electronic Publication: 2023 Jun 22.
Publication Type:
Journal Article
MeSH Terms:
Isoenzymes*
Enzyme Inhibitors*/pharmacology
Enzyme Inhibitors*/chemistry
Molecular Docking Simulation ; Glycogen Phosphorylase ; Indoles/pharmacology ; Indoles/chemistry
Academic Journal
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Title:
Isoenzyme characterization of Leishmania infantum toward checking the antioxidant activity of superoxide dismutase and glutathione peroxidase.
Authors:
Alishvandi M; ¹Department of Parasitology and Mycology, Shiraz University of Medical Sciences, Shiraz, Iran.
Bahrami S; Shahid Chamran University of Ahwaz, Ahvaz, Iran.
Rashidi S; Molecular and Medicine Research Center, Khomein University of Medical Sciences, Khomein, Iran. .; Department of Medical Laboratory Sciences, Khomein University of Medical Sciences, Khomein, Iran. .
Hatam G; Basic Sciences in Infectious Diseases Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. .
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Source:
BMC infectious diseases [BMC Infect Dis] 2024 Feb 15; Vol. 24 (1), pp. 208. Date of Electronic Publication: 2024 Feb 15.
Publication Type:
Journal Article
MeSH Terms:
Leishmania infantum*
Humans ; Isoenzymes/analysis ; Isoenzymes/metabolism ; Antioxidants/metabolism ; Glutathione Peroxidase ; Superoxide Dismutase/metabolism
Academic Journal
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Title:
Benzothiadiazinone-1,1-Dioxide Carbonic Anhydrase Inhibitors Suppress the Growth of Drug-Resistant Mycobacterium tuberculosis Strains.
Authors:
Bua S; Research Institute of the University of Bucharest (ICUB), University of Bucharest, 050095 Bucharest, Romania.
Bonardi A; Pharmaceutical and Nutraceutical Section, Laboratory of Molecular Modeling Cheminformatics & QSA, Neurofarba Department, University of Florence, Via U. Schiff 6, Sesto Fiorentino, 50019 Florence, Italy.
Mük GR; Faculty of Biology, University of Bucharest, Splaiul Independenței 91-95, 050095 Bucharest, Romania.; St. Stephen's Pneumoftiziology Hospital, Șoseaua Ștefan cel Mare 11, 020122 Bucharest, Romania.
Nocentini A; Pharmaceutical and Nutraceutical Section, Laboratory of Molecular Modeling Cheminformatics & QSA, Neurofarba Department, University of Florence, Via U. Schiff 6, Sesto Fiorentino, 50019 Florence, Italy.
Gratteri P; Pharmaceutical and Nutraceutical Section, Laboratory of Molecular Modeling Cheminformatics & QSA, Neurofarba Department, University of Florence, Via U. Schiff 6, Sesto Fiorentino, 50019 Florence, Italy.
Supuran CT; Pharmaceutical and Nutraceutical Section, Laboratory of Molecular Modeling Cheminformatics & QSA, Neurofarba Department, University of Florence, Via U. Schiff 6, Sesto Fiorentino, 50019 Florence, Italy.
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Source:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 23; Vol. 25 (5). Date of Electronic Publication: 2024 Feb 23.
Publication Type:
Journal Article
MeSH Terms:
Mycobacterium tuberculosis*
Carbonic Anhydrases*/metabolism
Tuberculosis*
Humans ; Molecular Structure ; Carbonic Anhydrase Inhibitors/pharmacology ; Isoenzymes/metabolism ; Structure-Activity Relationship ; Antitubercular Agents/pharmacology ; Carbonic Anhydrase IX
Academic Journal
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Title:
Inhibition of PDE-4 isoenzyme attenuates frequency and overall contractility of agonist-evoked ureteral phasic contractions.
Authors:
Lim I; Centre for Urology, Faculty of Health Sciences & Medicine, Bond University, Gold Coast, Queensland, Australia.
Masutani T; Department of Cell Physiology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.
Hashitani H; Department of Cell Physiology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.
Chess-Williams R; Centre for Urology, Faculty of Health Sciences & Medicine, Bond University, Gold Coast, Queensland, Australia.
Sellers D; Department of Cell Physiology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.
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Source:
Pharmacology research & perspectives [Pharmacol Res Perspect] 2024 Feb; Vol. 12 (1), pp. e1175.
Publication Type:
Journal Article
MeSH Terms:
Phosphodiesterase 4 Inhibitors*/pharmacology
Ureter*/physiology
Animals ; Swine ; Rolipram/pharmacology ; Cyclic Nucleotide Phosphodiesterases, Type 4 ; Isoenzymes ; Phosphodiesterase 5 Inhibitors/pharmacology ; Serotonin/pharmacology ; Tadalafil
Academic Journal
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Title:
A Key Role in Catalysis and Enzyme Thermostability of a Conserved Helix H5 Motif of Human Glutathione Transferase A1-1.
Authors:
Chronopoulou EG; Laboratory of Enzyme Technology, Department of Biotechnology, School of Applied Biology and Biotechnology, Agricultural University of Athens, 75 Iera Odos Street, 11855 Athens, Greece.
Mutabdzija L; Turku Bioscience Centre, University of Turku and Åbo Akademi University, 20520 Turku, Finland.
Poudel N; Turku Bioscience Centre, University of Turku and Åbo Akademi University, 20520 Turku, Finland.
Papageorgiou AC; Turku Bioscience Centre, University of Turku and Åbo Akademi University, 20520 Turku, Finland.
Labrou NE; Laboratory of Enzyme Technology, Department of Biotechnology, School of Applied Biology and Biotechnology, Agricultural University of Athens, 75 Iera Odos Street, 11855 Athens, Greece.
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Source:
International journal of molecular sciences [Int J Mol Sci] 2023 Feb 12; Vol. 24 (4). Date of Electronic Publication: 2023 Feb 12.
Publication Type:
Journal Article
MeSH Terms:
Glutathione Transferase*/genetics
Isoenzymes*/metabolism
Humans ; Models, Molecular ; Catalysis ; Kinetics ; Glutathione ; Binding Sites
Academic Journal
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Title:
Purification and biochemical characterization of two laccase isoenzymes isolated from Trichoderma harzianum S7113 and its application for bisphenol A degradation.
Authors:
Elsayed AM; Molecular Biology Department, Biotechnology Research Institute, National Research Centre, Dokki, Giza, 12622, Egypt.
Mahmoud M; Water Pollution Research Department, National Research Centre, 33 El-Buhouth St., Dokki, Giza, 12622, Egypt.
Abdel Karim GSA; Molecular Biology Department, Biotechnology Research Institute, National Research Centre, Dokki, Giza, 12622, Egypt.
Abdelraof M; Microbial Chemistry Department, Biotechnology Research Institute, National Research Centre, Dokki, Giza, 12622, Egypt.
Othman AM; Microbial Chemistry Department, Biotechnology Research Institute, National Research Centre, Dokki, Giza, 12622, Egypt. .
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Source:
Microbial cell factories [Microb Cell Fact] 2023 Jan 02; Vol. 22 (1), pp. 1. Date of Electronic Publication: 2023 Jan 02.
Publication Type:
Journal Article
MeSH Terms:
Laccase*/metabolism
Isoenzymes*/metabolism
Phenols ; Hydrogen-Ion Concentration ; Enzyme Stability ; Temperature
SCR Organism:
Trichoderma harzianum
Academic Journal
Full Text  Link opens in a new window Full TextDetails
Title:
Protein Kinase CK2α', More than a Backup of CK2α.
Authors:
Montenarh M; Medical Biochemistry and Molecular Biology, Saarland University, Building 44, 66421 Homburg, Germany.
Götz C; Medical Biochemistry and Molecular Biology, Saarland University, Building 44, 66421 Homburg, Germany.
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Source:
Cells [Cells] 2023 Dec 14; Vol. 12 (24). Date of Electronic Publication: 2023 Dec 14.
Publication Type:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Casein Kinase II*/chemistry
Casein Kinase II*/genetics
Casein Kinase II*/metabolism
Humans ; Animals ; Isoenzymes/chemistry ; Isoenzymes/genetics ; Isoenzymes/metabolism ; Holoenzymes/chemistry ; Holoenzymes/genetics ; Holoenzymes/metabolism
Academic Journal
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Title:
The Hydrolysis Rate of Paraoxonase-1 Q and R Isoenzymes: An In Silico Study Based on In Vitro Data.
Authors:
Karabulut S; Department of Chemistry and Biochemistry, University of Windsor, Windsor, ON N9B 3P4, Canada.
Mansour B; Department of Chemistry and Biochemistry, University of Windsor, Windsor, ON N9B 3P4, Canada.
Casanola-Martin GM; Department of Coatings and Polymeric Materials, North Dakota State University, 1735 NDSU Research Park Dr, Fargo, ND 58102, USA.
Rasulev B; Department of Coatings and Polymeric Materials, North Dakota State University, 1735 NDSU Research Park Dr, Fargo, ND 58102, USA.
Gauld JW; Department of Chemistry and Biochemistry, University of Windsor, Windsor, ON N9B 3P4, Canada.
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Source:
Molecules (Basel, Switzerland) [Molecules] 2022 Oct 11; Vol. 27 (20). Date of Electronic Publication: 2022 Oct 11.
Publication Type:
Journal Article
MeSH Terms:
Aryldialkylphosphatase*/genetics
Isoenzymes*/genetics
Humans ; Hydrolysis ; Linear Models ; Multivariate Analysis
Academic Journal
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Title:
Role of phospholipase C in catecholamine-induced increase in myocardial protein synthesis.
Authors:
Tappia PS; Asper Clinical Research Institute, St. Boniface Hospital, Winnipeg, R2H 2A6 MB Canada.
Ramjiawan B; Asper Clinical Research Institute, St. Boniface Hospital, Winnipeg, R2H 2A6 MB Canada.; Department of Pharmacology and Therapeutics, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, R3E 0T6 MB, Canada.
Dhalla NS; Institute of Cardiovascular Sciences, Department of Physiology and Pathophysiology, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, R3E 0J9 MB, Canada.
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Source:
Canadian journal of physiology and pharmacology [Can J Physiol Pharmacol] 2022 Oct 01; Vol. 100 (10), pp. 945-955. Date of Electronic Publication: 2022 Jun 29.
Publication Type:
Journal Article; Review
MeSH Terms:
Isoenzymes*/metabolism
Type C Phospholipases*/metabolism
Adenylyl Cyclases/metabolism ; Cardiomegaly/chemically induced ; Catecholamines/adverse effects ; GTP-Binding Proteins/adverse effects ; GTP-Binding Proteins/metabolism ; Humans ; Inositol/adverse effects ; Norepinephrine/pharmacology ; Phosphatidylinositols ; Receptors, Adrenergic/metabolism
Academic Journal
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Title:
Modifying the yeast very long chain fatty acid biosynthetic machinery by the expression of plant 3-ketoacyl CoA synthase isozymes.
Authors:
Stenback KE; Roy J Carver Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, IA, USA.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School Blavatnik Institute, Boston, MA, USA.
Flyckt KS; Roy J Carver Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, IA, USA.; Corteva Agriscience, Johnston, IA, USA.
Hoang T; Roy J Carver Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, IA, USA.; Department of Chemical Engineering, University of Michigan, Ann Arbor, MI, USA.
Campbell AA; Roy J Carver Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, IA, USA.; School of Education, Iowa State University, Ames, IA, USA.
Nikolau BJ; Roy J Carver Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, IA, USA. .; Center for Metabolic Biology, Iowa State University, Ames, IA, USA. .
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Source:
Scientific reports [Sci Rep] 2022 Aug 02; Vol. 12 (1), pp. 13235. Date of Electronic Publication: 2022 Aug 02.
Publication Type:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Isoenzymes*/genetics
Isoenzymes*/metabolism
Saccharomyces cerevisiae*/genetics
Saccharomyces cerevisiae*/metabolism
Carbon/metabolism ; Coenzyme A/metabolism ; Fatty Acids/metabolism ; Fatty Acids, Nonesterified/metabolism
Academic Journal
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Title:
Structural insights into N-terminal methionine cleavage by the human mitochondrial methionine aminopeptidase, MetAP1D.
Authors:
Lee Y; Research Institute, National Cancer Center, Goyang, 10408, Republic of Korea.
Kim H; Research Institute, National Cancer Center, Goyang, 10408, Republic of Korea.; Division of Medical Sciences, College of Medicine, Yonsei University, Seoul, 03722, Republic of Korea.
Lee E; Research Institute, National Cancer Center, Goyang, 10408, Republic of Korea.
Hahn H; Research Institute, National Cancer Center, Goyang, 10408, Republic of Korea.
Heo Y; Research Institute, National Cancer Center, Goyang, 10408, Republic of Korea.
Jang DM; Research Institute, National Cancer Center, Goyang, 10408, Republic of Korea.
Kwak K; Division of Medical Sciences, College of Medicine, Yonsei University, Seoul, 03722, Republic of Korea.
Kim HJ; College of Pharmacy, Woosuk University, Wanju, 55338, Republic of Korea. .
Kim HS; Research Institute, National Cancer Center, Goyang, 10408, Republic of Korea. .
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Source:
Scientific reports [Sci Rep] 2023 Dec 15; Vol. 13 (1), pp. 22326. Date of Electronic Publication: 2023 Dec 15.
Publication Type:
Journal Article
MeSH Terms:
Aminopeptidases*/metabolism
Methionine*/metabolism
Humans ; Isoenzymes ; Methionyl Aminopeptidases/metabolism ; Racemethionine
Academic Journal
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Title:
mRNA Levels of Aromatase, 5α-Reductase Isozymes, and Prostate Cancer-Related Genes in Plucked Hair from Young Men with Androgenic Alopecia.
Authors:
Sánchez P; Department of Biochemistry, Molecular Biology and Immunology, Faculty of Medicine, University of Granada, 18016 Granada, Spain.
Serrano Falcón C; Hospital of Guadix, 18500 Granada, Spain.
Martínez Rodríguez S; Department of Biochemistry, Molecular Biology and Immunology, Faculty of Medicine, University of Granada, 18016 Granada, Spain.
Torres JM; Department of Biochemistry, Molecular Biology and Immunology, Faculty of Medicine, University of Granada, 18016 Granada, Spain.
Serrano S; Department of Dermatology, Faculty of Medicine, University of Granada, 18012 Granada, Spain.
Ortega E; Department of Biochemistry, Molecular Biology and Immunology, Faculty of Medicine, University of Granada, 18016 Granada, Spain.
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Source:
International journal of molecular sciences [Int J Mol Sci] 2023 Dec 14; Vol. 24 (24). Date of Electronic Publication: 2023 Dec 14.
Publication Type:
Journal Article
MeSH Terms:
Cholestenone 5 alpha-Reductase*/genetics
Prostatic Neoplasms*/genetics
Male ; Humans ; Aromatase/genetics ; Isoenzymes/therapeutic use ; RNA, Messenger/genetics ; Hair ; Alopecia/genetics ; Alopecia/drug therapy
Academic Journal
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Title:
2H-chromene and 7H-furo-chromene derivatives selectively inhibit tumour associated human carbonic anhydrase IX and XII isoforms.
Authors:
Sequeira L; Department of Life and Environmental Sciences, University of Cagliari, Cittadella Universitaria, Monserrato, Italy.; CIQUP-IMS/Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, Porto, Portugal.
Distinto S; Department of Life and Environmental Sciences, University of Cagliari, Cittadella Universitaria, Monserrato, Italy.
Meleddu R; Department of Life and Environmental Sciences, University of Cagliari, Cittadella Universitaria, Monserrato, Italy.
Gaspari M; Department of Experimental and Clinical Medicine, Research Centre for Advanced Biochemistry and Molecular Biology, 'Magna Græcia' University of Catanzaro, Catanzaro, Italy.
Angeli A; Department of NEUROFARBA, Section of Pharmaceutical Sciences, University of Florence, Florence, Italy.
Cottiglia F; Department of Life and Environmental Sciences, University of Cagliari, Cittadella Universitaria, Monserrato, Italy.
Secci D; Department of Life and Environmental Sciences, University of Cagliari, Cittadella Universitaria, Monserrato, Italy.
Onali A; Department of Life and Environmental Sciences, University of Cagliari, Cittadella Universitaria, Monserrato, Italy.
Sanna E; Department of Life and Environmental Sciences, University of Cagliari, Cittadella Universitaria, Monserrato, Italy.
Borges F; CIQUP-IMS/Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, Porto, Portugal.
Uriarte E; Department of Organic Chemistry, Faculty of Pharmacy, University of Santiago de Compostela, Santiago de Compostela, Spain.
Alcaro S; Department of Health Sciences, 'Magna Græcia' University of Catanzaro, Catanzaro, Italy.
Supuran CT; Department of NEUROFARBA, Section of Pharmaceutical Sciences, University of Florence, Florence, Italy.
Maccioni E; Department of Life and Environmental Sciences, University of Cagliari, Cittadella Universitaria, Monserrato, Italy.
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Source:
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2023 Dec; Vol. 38 (1), pp. 2270183. Date of Electronic Publication: 2023 Oct 23.
Publication Type:
Journal Article
MeSH Terms:
Carbonic Anhydrases*/metabolism
Neoplasms*/drug therapy
Neoplasms*/pathology
Humans ; Carbonic Anhydrase IX ; Carbonic Anhydrase I ; Carbonic Anhydrase II ; Structure-Activity Relationship ; Carbonic Anhydrase Inhibitors/pharmacology ; Carbonic Anhydrase Inhibitors/chemistry ; Antigens, Neoplasm/chemistry ; Benzopyrans/pharmacology ; Isoenzymes/metabolism ; Molecular Structure
Academic Journal
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