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Wyświetlanie 1-20 z 20
Tytuł :
Biotin supplementation decreases the expression of the SERCA3 gene (ATP2A3) in Jurkat cells, thus, triggering unfolded protein response.
Autorzy :
Griffin JB; Department of Nutrition and Health Sciences, University of Nebraska at Lincoln, 68583-0806, USA.
Rodriguez-Melendez R
Dode L
Wuytack F
Zempleni J
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Źródło :
The Journal of nutritional biochemistry [J Nutr Biochem] 2006 Apr; Vol. 17 (4), pp. 272-81. Date of Electronic Publication: 2005 Jun 13.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Protein Folding*
Biotin/*administration & dosage
Calcium-Transporting ATPases/*genetics
Gene Expression/*drug effects
Biotinylation ; Calcium/analysis ; Carbon-Carbon Ligases/metabolism ; Cytoplasm/chemistry ; DNA-Binding Proteins/genetics ; Electrophoretic Mobility Shift Assay ; Humans ; Interleukin-2/metabolism ; Jurkat Cells ; Nuclear Proteins/genetics ; Pyruvate Carboxylase/metabolism ; RNA, Messenger/analysis ; Regulatory Factor X Transcription Factors ; Sarcoplasmic Reticulum Calcium-Transporting ATPases ; Transcription Factors
Czasopismo naukowe
Tytuł :
The expression of genes encoding ribosomal subunits and eukaryotic translation initiation factor 5A depends on biotin and bisnorbiotin in HepG2 cells.
Autorzy :
Rodriguez-Melendez R; Department of Nutrition and Health Sciences, University of Nebraska at Lincoln, 68583-0806, USA.
Griffin JB
Zempleni J
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Źródło :
The Journal of nutritional biochemistry [J Nutr Biochem] 2006 Jan; Vol. 17 (1), pp. 23-30. Date of Electronic Publication: 2005 Aug 02.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Gene Expression Regulation*
Biotin/*analogs & derivatives
Biotin/*physiology
Eukaryotic Initiation Factor-5/*metabolism
Carboxy-Lyases/metabolism ; Cell Line, Tumor ; Eukaryotic Initiation Factor-5/genetics ; Humans ; Multigene Family ; Oligonucleotide Array Sequence Analysis ; RNA, Messenger/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł :
K4, K9 and K18 in human histone H3 are targets for biotinylation by biotinidase.
Autorzy :
Kobza K; Department of Nutrition and Health Sciences, University of Nebraska-Lincoln, Lincoln, NE 68583-0806, USA.
Camporeale G
Rueckert B
Kueh A
Griffin JB
Sarath G
Zempleni J
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Źródło :
The FEBS journal [FEBS J] 2005 Aug; Vol. 272 (16), pp. 4249-59.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Biotin/*metabolism
Biotinidase/*metabolism
Histones/*metabolism
Amino Acid Sequence ; Blotting, Western ; Histones/chemistry ; Humans ; Immunohistochemistry ; Methylation ; Molecular Sequence Data ; Phosphorylation
Czasopismo naukowe
Tytuł :
High-throughput immunoblotting identifies biotin-dependent signaling proteins in HepG2 hepatocarcinoma cells.
Autorzy :
Rodriguez-Melendez R; Department of Nutrition and Health Sciences, University of Nebraska at Lincoln, Lincoln, NE, USA.
Griffin JB
Sarath G
Zempleni J
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Źródło :
The Journal of nutrition [J Nutr] 2005 Jul; Vol. 135 (7), pp. 1659-66.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Biotin/*metabolism
Neoplasm Proteins/*genetics
Signal Transduction/*physiology
Base Sequence ; Biotinylation ; Carboxylesterase/genetics ; Carboxylesterase/metabolism ; Carcinoma, Hepatocellular ; Cell Line, Tumor ; DNA Primers ; Humans ; Immunoblotting ; Liver Neoplasms ; Neoplasm Proteins/metabolism ; Oligonucleotide Probes ; Reverse Transcriptase Polymerase Chain Reaction
Czasopismo naukowe
Tytuł :
Biotin deficiency stimulates survival pathways in human lymphoma cells exposed to antineoplastic drugs.
Autorzy :
Griffin JB; Department of Nutrition and Health Sciences, University of Nebraska-Lincoln, Lincoln, NE 68583-0806, USA.
Zempleni J
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Źródło :
The Journal of nutritional biochemistry [J Nutr Biochem] 2005 Feb; Vol. 16 (2), pp. 96-103.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Antineoplastic Agents/*pharmacology
Biotin/*deficiency
Cell Survival/*drug effects
NF-kappa B/*metabolism
Apoptosis/genetics ; Biological Transport/drug effects ; Biotin/administration & dosage ; Biotin/physiology ; Biotinylation ; Carboxy-Lyases/metabolism ; Cell Nucleus/metabolism ; Culture Media ; Doxorubicin/pharmacology ; Drug Resistance, Neoplasm ; Genes, Reporter/genetics ; Humans ; Jurkat Cells ; Luciferases/genetics ; Minor Histocompatibility Antigens ; Proto-Oncogene Proteins c-bcl-2/genetics ; Vinblastine/pharmacology
Czasopismo naukowe
Tytuł :
Biotin supplementation increases expression of the cytochrome P450 1B1 gene in Jurkat cells, increasing the occurrence of single-stranded DNA breaks.
Autorzy :
Rodriguez-Melendez R; Departments of Nutrition and Health Sciences, University of Nebraska at Lincoln, Lincoln, NE, USA.
Griffin JB
Zempleni J
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Źródło :
The Journal of nutrition [J Nutr] 2004 Sep; Vol. 134 (9), pp. 2222-8.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
DNA, Single-Stranded*
Aryl Hydrocarbon Hydroxylases/*genetics
Biotin/*pharmacology
DNA Damage/*drug effects
Gene Expression/*drug effects
T-Lymphocytes/*physiology
Aryl Hydrocarbon Hydroxylases/metabolism ; Biotin/metabolism ; Blotting, Western ; Carboxy-Lyases/metabolism ; Cytochrome P-450 CYP1B1 ; Electrophoresis ; Humans ; Jurkat Cells ; Ligases/metabolism ; T-Lymphocytes/metabolism ; Transcription, Genetic
Czasopismo naukowe
Tytuł :
Biotin supply affects rates of cell proliferation, biotinylation of carboxylases and histones, and expression of the gene encoding the sodium-dependent multivitamin transporter in JAr choriocarcinoma cells.
Autorzy :
Crisp SE; Dept. of Nutritional Science and Dietetics, University of Nebraska at Lincoln, 316 Ruth Leverton Hall, Lincoln, NE 68583-0806, USA.
Griffin JB
White BR
Toombs CF
Camporeale G
Said HM
Zempleni J
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Źródło :
European journal of nutrition [Eur J Nutr] 2004 Feb; Vol. 43 (1), pp. 23-31. Date of Electronic Publication: 2004 Jan 06.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Symporters*
Biotin/*metabolism
Biotin/*pharmacology
Carboxy-Lyases/*metabolism
Carrier Proteins/*genetics
Histones/*metabolism
Membrane Glycoproteins/*genetics
Biotin/deficiency ; Biotinidase/genetics ; Biotinidase/metabolism ; Biotinylation ; Carrier Proteins/metabolism ; Cell Division/drug effects ; Choriocarcinoma ; Culture Media ; Dose-Response Relationship, Drug ; Gene Expression Regulation, Enzymologic/drug effects ; Gene Expression Regulation, Enzymologic/genetics ; Genes, Reporter ; Homeostasis ; Humans ; Membrane Glycoproteins/metabolism ; Placenta/metabolism ; Riboflavin/metabolism ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
The nuclear abundance of transcription factors Sp1 and Sp3 depends on biotin in Jurkat cells.
Autorzy :
Griffin JB; Department of Nutritional Science and Dietetics, University of Nebraska at Lincoln, Lincoln, NE, USA.
Rodriguez-Melendez R
Zempleni J
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Źródło :
The Journal of nutrition [J Nutr] 2003 Nov; Vol. 133 (11), pp. 3409-15.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Biotin/*pharmacology
DNA-Binding Proteins/*genetics
Gene Expression Regulation, Neoplastic/*drug effects
Sp1 Transcription Factor/*genetics
Transcription Factors/*genetics
Base Sequence ; Binding Sites ; Cell Nucleus/drug effects ; Cell Nucleus/genetics ; DNA-Binding Proteins/metabolism ; Humans ; Jurkat Cells ; Luciferases/genetics ; Oligonucleotide Probes ; Sp1 Transcription Factor/metabolism ; Sp3 Transcription Factor ; Transcription Factors/metabolism ; Transcription, Genetic ; Transfection ; Zinc Fingers
Czasopismo naukowe
Tytuł :
Monocarboxylate transporter 1 mediates biotin uptake in human peripheral blood mononuclear cells.
Autorzy :
Daberkow RL; Departments of. Nutritional Science and Dietetics, University of Nebraska at Lincoln, Lincoln, NE 68583, USA.
White BR
Cederberg RA
Griffin JB
Zempleni J
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Źródło :
The Journal of nutrition [J Nutr] 2003 Sep; Vol. 133 (9), pp. 2703-6.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Biotin/*pharmacology
Monocarboxylic Acid Transporters/*metabolism
Monocytes/*metabolism
Symporters/*metabolism
Animals ; Binding, Competitive ; Biological Transport/physiology ; Cell Division/physiology ; Cells, Cultured ; Cricetinae ; Extracellular Space/metabolism ; Gene Expression ; Humans ; Hydrogen-Ion Concentration ; Jurkat Cells ; Lactic Acid/metabolism ; Monocarboxylic Acid Transporters/genetics ; Monocytes/cytology ; Symporters/genetics ; Transfection
Czasopismo naukowe
Tytuł :
Interleukin-2 receptor-gamma -dependent endocytosis depends on biotin in Jurkat cells.
Autorzy :
Rodriguez-Melendez R; Department of Nutritional Science and Dietetics, University of Nebraska at Lincoln, Lincoln, Nebraska 68583, USA.
Camporeale G
Griffin JB
Zempleni J
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Źródło :
American journal of physiology. Cell physiology 2003 Feb; Vol. 284 (2), pp. C415-21. Date of Electronic Publication: 2002 Oct 16.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Biotin/*deficiency
Endocytosis/*immunology
Interleukin-2/*metabolism
Lymphocytes/*drug effects
Receptors, Interleukin-2/*metabolism
Biotin/pharmacology ; Carboxy-Lyases/metabolism ; Dose-Response Relationship, Drug ; Endocytosis/drug effects ; Endocytosis/genetics ; Gene Expression Regulation/drug effects ; Gene Expression Regulation/immunology ; Genetic Vectors ; Humans ; Jurkat Cells ; Lymphocytes/immunology ; Lymphocytes/metabolism ; Methylmalonyl-CoA Decarboxylase ; Receptors, Interleukin-2/drug effects ; Receptors, Interleukin-2/genetics
Czasopismo naukowe
Tytuł :
Exposure to UV light causes increased biotinylation of histones in Jurkat cells.
Autorzy :
Peters DM; Department of Nutritional Science and Dietetics, University of Nebraska at Lincoln, Lincoln 68583, USA.
Griffin JB
Stanley JS
Beck MM
Zempleni J
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Źródło :
American journal of physiology. Cell physiology 2002 Sep; Vol. 283 (3), pp. C878-84.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Ultraviolet Rays*
Biotin/*metabolism
Histones/*metabolism
Jurkat Cells/*drug effects
Jurkat Cells/*metabolism
Apoptosis ; Biotinylation ; Blotting, Western ; Carbon-Carbon Ligases/metabolism ; Caspase 3 ; Caspases/metabolism ; DNA Damage/radiation effects ; DNA Repair ; Dose-Response Relationship, Radiation ; Humans ; Jurkat Cells/cytology ; Microscopy, Confocal ; Mitochondria/metabolism ; Mitochondria/radiation effects ; Pyrimidine Dimers/metabolism ; Pyruvate Carboxylase/metabolism
Czasopismo naukowe
Tytuł :
Synthesis of a rabbit polyclonal antibody to the human sodium-dependent multivitamin transporter.
Autorzy :
Griffin JB; Department of Nutritional Sciences and Dietetics, University of Nebraska at Lincoln, 316 Ruth Leverton Hall, Lincoln, NE 68583-0806, USA.
Stanley JS
Zempleni J
Pokaż więcej
Źródło :
International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition [Int J Vitam Nutr Res] 2002 Jul; Vol. 72 (4), pp. 195-8.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Antibody Formation*
Biotin/*metabolism
Carrier Proteins/*immunology
Leukocytes, Mononuclear/*metabolism
Membrane Glycoproteins/*immunology
Animals ; Antibodies ; Blotting, Western ; Caco-2 Cells ; Carrier Proteins/isolation & purification ; Carrier Proteins/metabolism ; Cell Division ; Cell Line ; Homeostasis ; Humans ; Immune Sera/biosynthesis ; Immune Sera/immunology ; Membrane Glycoproteins/isolation & purification ; Membrane Glycoproteins/metabolism ; Pantothenic Acid/metabolism ; Rabbits ; Symporters ; Thioctic Acid/metabolism
Czasopismo naukowe
Tytuł :
Biotin uptake into human peripheral blood mononuclear cells increases early in the cell cycle, increasing carboxylase activities.
Autorzy :
Stanley JS; Arkansas Children's Hospital Research Institute, Little Rock, AR, USA.
Mock DM
Griffin JB
Zempleni J
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Źródło :
The Journal of nutrition [J Nutr] 2002 Jul; Vol. 132 (7), pp. 1854-9.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Biotin/*pharmacokinetics
Carbon-Carbon Ligases/*metabolism
Carboxy-Lyases/*metabolism
Monocytes/*cytology
Monocytes/*metabolism
Adult ; Carbon-Carbon Ligases/genetics ; Carbon-Nitrogen Ligases/genetics ; Carboxy-Lyases/genetics ; Cell Cycle/physiology ; Female ; Humans ; Male ; Methylmalonyl-CoA Decarboxylase ; Middle Aged ; RNA, Messenger/metabolism ; Reference Values ; Symporters/metabolism ; Thymidine/pharmacokinetics ; Time Factors
Czasopismo naukowe
Tytuł :
Biotin supply affects expression of biotin transporters, biotinylation of carboxylases and metabolism of interleukin-2 in Jurkat cells.
Autorzy :
Manthey KC; Department of Nutritional Science and Dietetics, University of Nebraska at Lincoln, Lincoln, NE 68583-0806, USA.
Griffin JB
Zempleni J
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Źródło :
The Journal of nutrition [J Nutr] 2002 May; Vol. 132 (5), pp. 887-92.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Biotin/*metabolism
Carboxy-Lyases/*metabolism
Gene Expression Regulation, Enzymologic/*drug effects
Interleukin-2/*metabolism
Jurkat Cells/*enzymology
Biotin/deficiency ; Biotin/pharmacology ; Biotinylation ; Culture Media ; Dose-Response Relationship, Drug ; Gene Expression Regulation, Enzymologic/genetics ; Histones/metabolism ; Humans ; Jurkat Cells/drug effects ; Methylmalonyl-CoA Decarboxylase ; Transcription, Genetic
Czasopismo naukowe
Tytuł :
Biotinidase catalyzes debiotinylation of histones.
Autorzy :
Ballard TD; Department of Nutritional Sciences and Dietetics, University of Nebraska at Lincoln, 68583-0806, USA.
Wolff J
Griffin JB
Stanley JS
van Calcar S
Zempleni J
Pokaż więcej
Źródło :
European journal of nutrition [Eur J Nutr] 2002 Apr; Vol. 41 (2), pp. 78-84.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Amidohydrolases/*deficiency
Amidohydrolases/*metabolism
Biotin/*metabolism
Histones/*metabolism
Metabolism, Inborn Errors/*enzymology
Biotinidase ; Biotinylation ; Catalysis ; Humans ; Hydrogen-Ion Concentration ; Lymphocytes ; Plasma/enzymology
Czasopismo naukowe
    Wyświetlanie 1-20 z 20

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