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Wyświetlanie 1-12 z 12
Tytuł :
Local coupling of TRPC6 to ANO1/TMEM16A channels in smooth muscle cells amplifies vasoconstriction in cerebral arteries.
Autorzy :
Wang Q; Department of Physiology, University of Tennessee Health Science Center, Memphis, Tennessee.
Leo MD; Department of Physiology, University of Tennessee Health Science Center, Memphis, Tennessee.
Narayanan D; Department of Physiology, University of Tennessee Health Science Center, Memphis, Tennessee.
Kuruvilla KP; Department of Physiology, University of Tennessee Health Science Center, Memphis, Tennessee.
Jaggar JH; Department of Physiology, University of Tennessee Health Science Center, Memphis, Tennessee .
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Źródło :
American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2016 Jun 01; Vol. 310 (11), pp. C1001-9. Date of Electronic Publication: 2016 May 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms :
Vasoconstriction*/drug effects
Chloride Channels/*metabolism
Muscle, Smooth, Vascular/*metabolism
Myocytes, Smooth Muscle/*metabolism
TRPC Cation Channels/*metabolism
Animals ; Anoctamin-1 ; Calcium Chelating Agents/pharmacology ; Calcium Signaling ; Cerebral Arteries/metabolism ; Chloride Channels/antagonists & inhibitors ; Chloride Channels/genetics ; Male ; Membrane Potentials ; Muscle, Smooth, Vascular/drug effects ; Myocytes, Smooth Muscle/drug effects ; RNA Interference ; Rats, Sprague-Dawley ; TRPC Cation Channels/agonists ; Tissue Culture Techniques ; Transfection ; Vasoconstrictor Agents/pharmacology
Czasopismo naukowe
Tytuł :
Rab25 influences functional Cav1.2 channel surface expression in arterial smooth muscle cells.
Autorzy :
Bannister JP; Department of Physiology, University of Tennessee Health Science Center, Memphis, Tennessee.
Bulley S; Department of Physiology, University of Tennessee Health Science Center, Memphis, Tennessee.
Leo MD; Department of Physiology, University of Tennessee Health Science Center, Memphis, Tennessee.
Kidd MW; Department of Physiology, University of Tennessee Health Science Center, Memphis, Tennessee.
Jaggar JH; Department of Physiology, University of Tennessee Health Science Center, Memphis, Tennessee .
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Źródło :
American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2016 Jun 01; Vol. 310 (11), pp. C885-93. Date of Electronic Publication: 2016 Apr 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms :
Calcium Channels, L-Type/*metabolism
Muscle, Smooth, Vascular/*enzymology
Myocytes, Smooth Muscle/*enzymology
rab GTP-Binding Proteins/*metabolism
Animals ; Cells, Cultured ; Cerebral Arteries/enzymology ; Lysosomes/metabolism ; Male ; Membrane Potentials ; Proteasome Endopeptidase Complex/metabolism ; Protein Transport ; Proteolysis ; RNA Interference ; Rats, Sprague-Dawley ; Signal Transduction ; Transfection ; Vasoconstriction ; rab GTP-Binding Proteins/genetics
Czasopismo naukowe
Tytuł :
Angiotensin II stimulates internalization and degradation of arterial myocyte plasma membrane BK channels to induce vasoconstriction.
Autorzy :
Leo MD; Department of Physiology, University of Tennessee Health Science Center, Memphis, Tennessee.
Bulley S; Department of Physiology, University of Tennessee Health Science Center, Memphis, Tennessee.
Bannister JP; Department of Physiology, University of Tennessee Health Science Center, Memphis, Tennessee.
Kuruvilla KP; Department of Physiology, University of Tennessee Health Science Center, Memphis, Tennessee.
Narayanan D; Department of Physiology, University of Tennessee Health Science Center, Memphis, Tennessee.
Jaggar JH; Department of Physiology, University of Tennessee Health Science Center, Memphis, Tennessee .
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Źródło :
American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2015 Sep 15; Vol. 309 (6), pp. C392-402. Date of Electronic Publication: 2015 Jul 15.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Angiotensin II/*pharmacology
Cell Membrane/*metabolism
Cerebral Arteries/*metabolism
Large-Conductance Calcium-Activated Potassium Channels/*metabolism
Muscle Cells/*metabolism
Proteolysis/*drug effects
Vasoconstriction/*drug effects
Animals ; Cerebral Arteries/drug effects ; Endosomes/drug effects ; Endosomes/metabolism ; Male ; Membrane Potentials/drug effects ; Muscle Cells/drug effects ; Muscle, Smooth, Vascular/drug effects ; Muscle, Smooth, Vascular/metabolism ; Myocytes, Smooth Muscle/drug effects ; Myocytes, Smooth Muscle/metabolism ; Rats ; Rats, Sprague-Dawley ; Vasoconstrictor Agents/pharmacology
Czasopismo naukowe
Tytuł :
Vasoconstriction resulting from dynamic membrane trafficking of TRPM4 in vascular smooth muscle cells.
Autorzy :
Crnich R; Vascular Physiology Research Group, Department of Biomedical Sciences, Colorado State University, Fort Collins, Colorado, USA.
Amberg GC
Leo MD
Gonzales AL
Tamkun MM
Jaggar JH
Earley S
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Źródło :
American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2010 Sep; Vol. 299 (3), pp. C682-94. Date of Electronic Publication: 2010 Jul 07.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Muscle, Smooth, Vascular/*metabolism
Myocytes, Smooth Muscle/*metabolism
TRPM Cation Channels/*metabolism
Animals ; Cell Membrane/metabolism ; Cells, Cultured ; Cerebral Arteries/cytology ; Cerebral Arteries/metabolism ; Enzyme Activators/pharmacology ; Male ; Membrane Potentials ; Mice ; Muscle Contraction ; Protein Kinase C-delta/physiology ; Protein Transport ; Rats ; Rats, Sprague-Dawley ; Tetradecanoylphorbol Acetate/pharmacology
Czasopismo naukowe
Tytuł :
Subtype identification and functional characterization of ryanodine receptors in rat cerebral artery myocytes.
Autorzy :
Vaithianathan T; Department Pharmacology, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA.
Narayanan D
Asuncion-Chin MT
Jeyakumar LH
Liu J
Fleischer S
Jaggar JH
Dopico AM
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Źródło :
American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2010 Aug; Vol. 299 (2), pp. C264-78. Date of Electronic Publication: 2010 May 05.
Typ publikacji :
Comparative Study; Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Cerebral Arteries/*cytology
Cerebral Arteries/*physiology
Muscle Cells/*physiology
Protein Subunits/*physiology
Ryanodine Receptor Calcium Release Channel/*physiology
Animals ; Cells, Cultured ; Cerebral Arteries/chemistry ; Female ; Male ; Muscle Cells/chemistry ; Protein Subunits/analysis ; Rats ; Rats, Sprague-Dawley ; Ryanodine Receptor Calcium Release Channel/analysis
Czasopismo naukowe
Tytuł :
Type 1 inositol 1,4,5-trisphosphate receptors mediate UTP-induced cation currents, Ca2+ signals, and vasoconstriction in cerebral arteries.
Autorzy :
Zhao G; Dept. of Physiology, Univ. of Tennessee Health Science Center, Memphis, TN 38163, USA.
Adebiyi A
Blaskova E
Xi Q
Jaggar JH
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Źródło :
American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2008 Nov; Vol. 295 (5), pp. C1376-84. Date of Electronic Publication: 2008 Sep 17.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Calcium Signaling*/drug effects
Vasoconstriction*/drug effects
Inositol 1,4,5-Trisphosphate Receptors/*metabolism
Muscle, Smooth, Vascular/*metabolism
Uridine Triphosphate/*metabolism
Animals ; Boron Compounds/pharmacology ; Cations ; Cell Membrane/metabolism ; Cerebral Arteries/metabolism ; In Vitro Techniques ; Inositol 1,4,5-Trisphosphate Receptors/antagonists & inhibitors ; Inositol 1,4,5-Trisphosphate Receptors/genetics ; Macrocyclic Compounds/pharmacology ; Muscle, Smooth, Vascular/drug effects ; Oxazoles/pharmacology ; Protein Isoforms ; RNA Interference ; RNA, Messenger/metabolism ; RNA, Small Interfering/metabolism ; Rats ; Rats, Sprague-Dawley ; Sarcoplasmic Reticulum/metabolism
Czasopismo naukowe
Tytuł :
Hypoxia reduces KCa channel activity by inducing Ca2+ spark uncoupling in cerebral artery smooth muscle cells.
Autorzy :
Zhao G; Dept. of Physiology, University of Tennessee Health Science Center, Memphis, TN 38163, USA.
Adebiyi A
Xi Q
Jaggar JH
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Źródło :
American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2007 Jun; Vol. 292 (6), pp. C2122-8. Date of Electronic Publication: 2007 Feb 21.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Hypoxia*
Calcium/*metabolism
Cerebral Arteries/*metabolism
Myocytes, Smooth Muscle/*metabolism
Potassium Channels/*metabolism
Animals ; Cerebral Arteries/cytology ; Electrophysiology ; Female ; Male ; Oxygen/metabolism ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
TNF-alpha dilates cerebral arteries via NAD(P)H oxidase-dependent Ca2+ spark activation.
Autorzy :
Cheranov SY; Department of Physiology, College of Medicine, University of Tennessee Health Science Center, 426 Nash Research Bldg., Memphis, 38163, USA.
Jaggar JH
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Źródło :
American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2006 Apr; Vol. 290 (4), pp. C964-71. Date of Electronic Publication: 2005 Nov 02.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Calcium Signaling/*physiology
Cerebral Arteries/*drug effects
Cerebral Arteries/*metabolism
NADPH Oxidases/*metabolism
Tumor Necrosis Factor-alpha/*pharmacology
Vasodilation/*physiology
Animals ; Calcium-Transporting ATPases/metabolism ; Cerebral Arteries/cytology ; Endothelium, Vascular/cytology ; Endothelium, Vascular/metabolism ; Female ; Humans ; Male ; Myocytes, Smooth Muscle/cytology ; Myocytes, Smooth Muscle/drug effects ; Myocytes, Smooth Muscle/metabolism ; Patch-Clamp Techniques ; Potassium Channels, Calcium-Activated/metabolism ; Rats ; Rats, Sprague-Dawley ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł :
Injury-elicited differential transcriptional regulation of phospholipid growth factor receptors in the cornea.
Autorzy :
Wang DA; Department of Physiology, University of Tennessee Health Sciences Center, Memphis, Tennessee 38163, USA.
Du H
Jaggar JH
Brindley DN
Tigyi GJ
Watsky MA
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Źródło :
American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2002 Dec; Vol. 283 (6), pp. C1646-54. Date of Electronic Publication: 2002 Aug 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Corneal Injuries*
Receptors, G-Protein-Coupled*
Transcription, Genetic*
Eye Injuries/*genetics
Eye Injuries/*metabolism
Receptors, Cell Surface/*genetics
Animals ; Cloning, Molecular ; Cornea/metabolism ; Cornea/pathology ; Endothelium, Corneal/drug effects ; Endothelium, Corneal/metabolism ; Endothelium, Corneal/pathology ; Epithelium, Corneal/metabolism ; Eye Injuries/pathology ; In Vitro Techniques ; Lysophospholipids/pharmacology ; Phosphatidate Phosphatase/genetics ; Phosphatidate Phosphatase/metabolism ; RNA, Messenger/metabolism ; Rabbits ; Receptors, Lysophosphatidic Acid ; Receptors, Lysophospholipid ; Reverse Transcriptase Polymerase Chain Reaction
Czasopismo naukowe
Tytuł :
Intravascular pressure regulates local and global Ca(2+) signaling in cerebral artery smooth muscle cells.
Autorzy :
Jaggar JH; Department of Physiology, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA.
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Źródło :
American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2001 Aug; Vol. 281 (2), pp. C439-48.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Blood Pressure/*physiology
Calcium Signaling/*physiology
Cerebral Arteries/*physiology
Muscle, Smooth, Vascular/*physiology
Animals ; Blood Pressure/drug effects ; Calcium/metabolism ; Calcium Channel Blockers/pharmacology ; Cerebral Arteries/cytology ; Cerebral Arteries/drug effects ; Diltiazem/pharmacology ; Electric Conductivity ; Electrophysiology ; Enzyme Inhibitors/pharmacology ; Female ; Homeostasis ; Male ; Muscle, Smooth, Vascular/cytology ; Muscle, Smooth, Vascular/drug effects ; Rats ; Rats, Sprague-Dawley ; Ryanodine/pharmacology ; Thapsigargin/pharmacology ; Vasoconstrictor Agents/pharmacology
Czasopismo naukowe
Tytuł :
Differential regulation of Ca(2+) sparks and Ca(2+) waves by UTP in rat cerebral artery smooth muscle cells.
Autorzy :
Jaggar JH; Department of Pharmacology, the University of Vermont, Burlington, Vermont 05405, USA.
Nelson MT
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Źródło :
American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2000 Nov; Vol. 279 (5), pp. C1528-39.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Calcium/*physiology
Cerebral Arteries/*metabolism
Muscle, Smooth, Vascular/*metabolism
Uridine Triphosphate/*physiology
Animals ; Cadmium/pharmacology ; Caffeine/pharmacology ; Calcium/metabolism ; Calcium Channel Blockers/pharmacology ; Calcium Signaling/drug effects ; Cerebral Arteries/cytology ; Drug Synergism ; Electric Conductivity ; Enzyme Activation ; Female ; In Vitro Techniques ; Male ; Muscle, Smooth, Vascular/cytology ; Patch-Clamp Techniques ; Potassium/physiology ; Rats ; Rats, Sprague-Dawley ; Type C Phospholipases/metabolism
Czasopismo naukowe
Tytuł :
Calcium sparks in smooth muscle.
Autorzy :
Jaggar JH; Department of Pharmacology, College of Medicine, The University of Vermont, Burlington, Vermont 05405, USA.
Porter VA
Lederer WJ
Nelson MT
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Źródło :
American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2000 Feb; Vol. 278 (2), pp. C235-56.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.; Review
MeSH Terms :
Calcium/*metabolism
Calcium Channels/*metabolism
Muscle, Smooth/*chemistry
Muscle, Smooth/*metabolism
Animals ; Calcium Signaling/physiology ; Humans
Czasopismo naukowe
    Wyświetlanie 1-12 z 12

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