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    Tytuł:
    Novel Dormancy Mechanism of Castration Resistance in Bone Metastatic Prostate Cancer Organoids.
    Autorzy:
    Lee S; Department of Urology, University of California San Diego, La Jolla, CA 92093, USA.; Moores Cancer Center, University of California San Diego, La Jolla, CA 92093, USA.; Rady Children's Hospital, San Diego, CA 92123, USA.
    Mendoza TR; Department of Urology, University of California San Diego, La Jolla, CA 92093, USA.; Moores Cancer Center, University of California San Diego, La Jolla, CA 92093, USA.
    Burner DN; Department of Urology, University of California San Diego, La Jolla, CA 92093, USA.; Moores Cancer Center, University of California San Diego, La Jolla, CA 92093, USA.
    Muldong MT; Department of Urology, University of California San Diego, La Jolla, CA 92093, USA.; Moores Cancer Center, University of California San Diego, La Jolla, CA 92093, USA.
    Wu CCN; Moores Cancer Center, University of California San Diego, La Jolla, CA 92093, USA.; Department of Medicine, University of California San Diego, La Jolla, CA 92093, USA.
    Arreola-Villanueva C; Department of Urology, University of California San Diego, La Jolla, CA 92093, USA.; Moores Cancer Center, University of California San Diego, La Jolla, CA 92093, USA.
    Zuniga A; Department of Urology, University of California San Diego, La Jolla, CA 92093, USA.; Moores Cancer Center, University of California San Diego, La Jolla, CA 92093, USA.
    Greenburg O; Department of Urology, University of California San Diego, La Jolla, CA 92093, USA.; Moores Cancer Center, University of California San Diego, La Jolla, CA 92093, USA.
    Zhu WY; Department of Urology, University of California San Diego, La Jolla, CA 92093, USA.; Moores Cancer Center, University of California San Diego, La Jolla, CA 92093, USA.
    Murtadha J; Department of Urology, University of California San Diego, La Jolla, CA 92093, USA.; Moores Cancer Center, University of California San Diego, La Jolla, CA 92093, USA.
    Koutouan E; Department of Urology, University of California San Diego, La Jolla, CA 92093, USA.; Moores Cancer Center, University of California San Diego, La Jolla, CA 92093, USA.
    Pineda N; Department of Urology, University of California San Diego, La Jolla, CA 92093, USA.; Moores Cancer Center, University of California San Diego, La Jolla, CA 92093, USA.
    Pham H; Department of Urology, University of California San Diego, La Jolla, CA 92093, USA.; Moores Cancer Center, University of California San Diego, La Jolla, CA 92093, USA.
    Kang SG; Department of Urology, Korea University College of Medicine, Seongbuk-Gu, Seoul 02841, Korea.
    Kim HT; Department of Urology, School of Medicine, Kyungpook National University, Daegu 41944, Korea.
    Pineda G; Department of Medicine, University of California San Diego, La Jolla, CA 92093, USA.
    Lennon KM; Department of Medicine, University of California San Diego, La Jolla, CA 92093, USA.
    Cacalano NA; Department of Radiation Oncology, University of California, Los Angeles, CA 90095, USA.
    Jamieson CHM; Moores Cancer Center, University of California San Diego, La Jolla, CA 92093, USA.; Department of Urology, Korea University College of Medicine, Seongbuk-Gu, Seoul 02841, Korea.
    Kane CJ; Department of Urology, University of California San Diego, La Jolla, CA 92093, USA.; Moores Cancer Center, University of California San Diego, La Jolla, CA 92093, USA.
    Kulidjian AA; Scripps MD Anderson Cancer Center, La Jolla, CA 92093, USA.
    Gaasterland T; Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA 92093, USA.; Institute for Genomic Medicine, University of California San Diego, La Jolla, CA 92093, USA.
    Jamieson CAM; Department of Urology, University of California San Diego, La Jolla, CA 92093, USA.; Moores Cancer Center, University of California San Diego, La Jolla, CA 92093, USA.
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    Źródło:
    International journal of molecular sciences [Int J Mol Sci] 2022 Mar 16; Vol. 23 (6). Date of Electronic Publication: 2022 Mar 16.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Bone Neoplasms/*genetics
    Gene Expression Profiling/*methods
    Gene Expression Regulation, Neoplastic/*genetics
    Organoids/*metabolism
    Prostatic Neoplasms, Castration-Resistant/*genetics
    Androgens/pharmacology ; Angiotensin-Converting Enzyme 2/genetics ; Angiotensin-Converting Enzyme 2/metabolism ; Animals ; Benzamides/pharmacology ; Bone Neoplasms/metabolism ; Bone Neoplasms/secondary ; COVID-19/genetics ; COVID-19/metabolism ; COVID-19/virology ; Drug Resistance, Neoplasm/drug effects ; Drug Resistance, Neoplasm/genetics ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; Male ; Mice ; Nitriles/pharmacology ; Phenylthiohydantoin/pharmacology ; Prostatic Neoplasms/genetics ; Prostatic Neoplasms/metabolism ; Prostatic Neoplasms/pathology ; Prostatic Neoplasms, Castration-Resistant/metabolism ; Prostatic Neoplasms, Castration-Resistant/pathology ; Receptors, Virus/genetics ; Receptors, Virus/metabolism ; SARS-CoV-2/metabolism ; SARS-CoV-2/physiology ; Serine Endopeptidases/genetics ; Serine Endopeptidases/metabolism ; Transplantation, Heterologous ; Virus Internalization
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Neoadjuvant rituximab modulates the tumor immune environment in patients with high risk prostate cancer.
    Autorzy:
    Ryan ST; Department of Urology, UCSD Moores Cancer Center, University of California San Diego School of Medicine, 3855 Health Sciences Drive, Mail Code: 0987, La Jolla, CA, 92093-0987, USA.
    Zhang J; Department of Pharmacology, University of California San Diego School of Medicine, La Jolla, CA, USA.
    Burner DN; Department of Urology, UCSD Moores Cancer Center, University of California San Diego School of Medicine, 3855 Health Sciences Drive, Mail Code: 0987, La Jolla, CA, 92093-0987, USA.
    Liss M; Department of Urology, University of Texas Health Science Center San Antonio, San Antonio, TX, USA.
    Pittman E; Department of Pharmacology, University of California San Diego School of Medicine, La Jolla, CA, USA.
    Muldong M; Department of Urology, UCSD Moores Cancer Center, University of California San Diego School of Medicine, 3855 Health Sciences Drive, Mail Code: 0987, La Jolla, CA, 92093-0987, USA.
    Shabaik A; Department of Pathology, University of California San Diego School of Medicine, La Jolla, CA, USA.
    Woo J; Department of Urology, UCSD Moores Cancer Center, University of California San Diego School of Medicine, 3855 Health Sciences Drive, Mail Code: 0987, La Jolla, CA, 92093-0987, USA.
    Basler N; Department of Urology, UCSD Moores Cancer Center, University of California San Diego School of Medicine, 3855 Health Sciences Drive, Mail Code: 0987, La Jolla, CA, 92093-0987, USA.
    Cunha J; Department of Urology, UCSD Moores Cancer Center, University of California San Diego School of Medicine, 3855 Health Sciences Drive, Mail Code: 0987, La Jolla, CA, 92093-0987, USA.
    Shalapour S; Department of Pharmacology, University of California San Diego School of Medicine, La Jolla, CA, USA.
    Estrada MV; Biorepository and Tissue Technology Shared Resource at the University of California San Diego School of Medicine, La Jolla, CA, USA.
    Karin M; Department of Pharmacology, University of California San Diego School of Medicine, La Jolla, CA, USA.; Department of Pharmacology, University of California San Diego School of Medicine, La Jolla, CA, USA.
    Messer K; Department of Pharmacology, University of California San Diego School of Medicine, La Jolla, CA, USA.; Division of Biostatistics, Department of Family and Preventive Medicine, University of California San Diego School of Medicine, La Jolla, CA, USA.
    Howell S; Department of Pharmacology, University of California San Diego School of Medicine, La Jolla, CA, USA.; Department of Medicine, University of California San Diego School of Medicine, La Jolla, CA, USA.
    Kane CJ; Department of Urology, UCSD Moores Cancer Center, University of California San Diego School of Medicine, 3855 Health Sciences Drive, Mail Code: 0987, La Jolla, CA, 92093-0987, USA.; Department of Pharmacology, University of California San Diego School of Medicine, La Jolla, CA, USA.
    Jamieson CAM; Department of Urology, UCSD Moores Cancer Center, University of California San Diego School of Medicine, 3855 Health Sciences Drive, Mail Code: 0987, La Jolla, CA, 92093-0987, USA. .; Department of Pharmacology, University of California San Diego School of Medicine, La Jolla, CA, USA. .
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    Źródło:
    Journal of translational medicine [J Transl Med] 2020 May 28; Vol. 18 (1), pp. 214. Date of Electronic Publication: 2020 May 28.
    Typ publikacji:
    Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Neoadjuvant Therapy*
    Prostatic Neoplasms*/drug therapy
    Prostatic Neoplasms*/surgery
    Animals ; B7-H1 Antigen ; Humans ; Lymphocytes, Tumor-Infiltrating ; Male ; Mice ; Prostatectomy ; Rituximab/therapeutic use ; T-Lymphocytes ; Tumor Microenvironment
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    The Impact of Whole Genome Data on Therapeutic Decision-Making in Metastatic Prostate Cancer: A Retrospective Analysis.
    Autorzy:
    Crumbaker M; Garvan Institute of Medical Research, Darlinghurst NSW 2010, Australia.; St. Vincent's Clinical School, University of New South Wales, Sydney, Randwick NSW 2031, Australia.; Kinghorn Cancer Centre, Department of Medical Oncology, St. Vincent's Hospital, Darlinghurst NSW 2010, Australia.
    Chan EKF; Garvan Institute of Medical Research, Darlinghurst NSW 2010, Australia.; St. Vincent's Clinical School, University of New South Wales, Sydney, Randwick NSW 2031, Australia.
    Gong T; Garvan Institute of Medical Research, Darlinghurst NSW 2010, Australia.; Central Clinical School, University of Sydney, Sydney, Camperdown NSW 2050, Australia.
    Corcoran N; Australian Prostate Cancer Research Centre Epworth, Richmond VIC 3121, Australia.; Department of Surgery, University of Melbourne, Melbourne VIC 3010, Australia.; Division of Urology, Royal Melbourne Hospital, Melbourne VIC 3050, Australia.
    Jaratlerdsiri W; Garvan Institute of Medical Research, Darlinghurst NSW 2010, Australia.
    Lyons RJ; Garvan Institute of Medical Research, Darlinghurst NSW 2010, Australia.
    Haynes AM; Garvan Institute of Medical Research, Darlinghurst NSW 2010, Australia.
    Kulidjian AA; Department of Orthopedic Surgery, Scripps Clinic, La Jolla, CA 92037, USA..; Orthopedic Oncology Program, Scripps MD Anderson Cancer Center, La Jolla CA 92037, USA.
    Kalsbeek AMF; Garvan Institute of Medical Research, Darlinghurst NSW 2010, Australia.
    Petersen DC; The Centre for Proteomic and Genomic Research, Cape Town 7925, South Africa.
    Stricker PD; Department of Urology, St. Vincent's Hospital, Darlinghurst NSW 2010, Australia.
    Jamieson CAM; Department of Urology, Moores Cancer Center, University of California, San Diego, La Jolla, CA 92037, USA.
    Croucher PI; Garvan Institute of Medical Research, Darlinghurst NSW 2010, Australia.; School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, Randwick, NSW 2031, Australia.
    Hovens CM; Australian Prostate Cancer Research Centre Epworth, Richmond VIC 3121, Australia.; Department of Surgery, University of Melbourne, Melbourne VIC 3010, Australia.
    Joshua AM; Garvan Institute of Medical Research, Darlinghurst NSW 2010, Australia.; St. Vincent's Clinical School, University of New South Wales, Sydney, Randwick NSW 2031, Australia.; Kinghorn Cancer Centre, Department of Medical Oncology, St. Vincent's Hospital, Darlinghurst NSW 2010, Australia.
    Hayes VM; Garvan Institute of Medical Research, Darlinghurst NSW 2010, Australia.; St. Vincent's Clinical School, University of New South Wales, Sydney, Randwick NSW 2031, Australia.; Central Clinical School, University of Sydney, Sydney, Camperdown NSW 2050, Australia.
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    Źródło:
    Cancers [Cancers (Basel)] 2020 May 07; Vol. 12 (5). Date of Electronic Publication: 2020 May 07.
    Typ publikacji:
    Journal Article
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
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