Autor: "Janmaat ML" - OpacWWW

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Tytuł:: Monoclonal antibodies targeting CD38 in hematological malignancies and beyond.
Autorzy:: van de Donk NW; Department of Hematology, VU University Medical Center, Amsterdam, the Netherlands.
Janmaat ML; Genmab, Utrecht, the Netherlands.
Mutis T; Department of Hematology, VU University Medical Center, Amsterdam, the Netherlands.
Lammerts van Bueren JJ; Genmab, Utrecht, the Netherlands.
Ahmadi T; Janssen Research and Development, Spring House, PA, USA.
Sasser AK; Janssen Research and Development, Spring House, PA, USA.
Lokhorst HM; Department of Hematology, VU University Medical Center, Amsterdam, the Netherlands.
Parren PW; Genmab, Utrecht, the Netherlands.; Department of Cancer and inflammation Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark.; Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, the Netherlands.; Pokaż więcej
Źródło:: Immunological reviews [Immunol Rev] 2016 Mar; Vol. 270 (1), pp. 95-112.
Typ publikacji:: Journal Article; Review
MeSH Terms:: ADP-ribosyl Cyclase 1/*antagonists & inhibitors
Antibodies, Monoclonal/*therapeutic use
Antineoplastic Agents/*therapeutic use
Hematologic Neoplasms/*drug therapy
ADP-ribosyl Cyclase 1/genetics ; ADP-ribosyl Cyclase 1/metabolism ; Animals ; Antibodies, Monoclonal/pharmacology ; Antibodies, Monoclonal, Humanized/pharmacology ; Antibodies, Monoclonal, Humanized/therapeutic use ; Antineoplastic Agents/pharmacology ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Clinical Studies as Topic ; Cytotoxicity, Immunologic ; Drug Evaluation, Preclinical ; Drug Resistance, Neoplasm ; Gene Expression Regulation, Neoplastic/drug effects ; Hematologic Neoplasms/genetics ; Hematologic Neoplasms/immunology ; Hematologic Neoplasms/metabolism ; Humans ; Immunomodulation/drug effects ; Protein Binding ; Recurrence ; Treatment Outcome

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Tytuł:: Basic fibroblast growth factor-mediated overexpression of vascular endothelial growth factor in 1F6 human melanoma cells is regulated by activation of PI-3K and p38 MAPK.
Autorzy:: Fontijn D; Department of Medical Oncology, VU University Medical Center, Amsterdam, The Netherlands.
Bosch LJ
Duyndam MC
van Berkel MP
Janmaat ML
Boven E; Pokaż więcej
Źródło:: Cellular oncology : the official journal of the International Society for Cellular Oncology [Cell Oncol] 2009; Vol. 31 (3), pp. 179-90.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Gene Expression Regulation, Neoplastic*
Fibroblast Growth Factor 2/*metabolism
Melanoma/*enzymology
Phosphatidylinositol 3-Kinases/*metabolism
Vascular Endothelial Growth Factor A/*genetics
p38 Mitogen-Activated Protein Kinases/*metabolism
Cell Line, Tumor ; Enzyme Activation ; Fibroblast Growth Factor 2/genetics ; Humans ; Melanoma/genetics ; Melanoma/metabolism ; Phosphatidylinositol 3-Kinases/genetics ; Signal Transduction ; Vascular Endothelial Growth Factor A/metabolism ; p38 Mitogen-Activated Protein Kinases/genetics

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