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    Wyświetlanie 1-3 z 3
    Tytuł:
    Induction of durable remission by dual immunotherapy in SHIV-infected ART-suppressed macaques.
    Autorzy:
    Lim SY; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
    Lee J; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
    Osuna CE; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
    Vikhe P; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
    Schalk DR; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI 53715, USA.
    Chen E; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
    Fray E; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
    Kumar M; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
    Schultz-Darken N; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI 53715, USA.
    Rakasz E; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI 53715, USA.
    Capuano S; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI 53715, USA.
    Ladd RA; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI 53715, USA.
    Gil HM; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI 53715, USA.
    Evans DT; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI 53715, USA.
    Jeng EK; Altor Biosciences, Miramar, FL 33027, USA.
    Seaman M; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
    Martin M; Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
    Van Dorp C; Los Alamos National Laboratory, Los Alamos, NM 87545, USA.
    Perelson AS; Los Alamos National Laboratory, Los Alamos, NM 87545, USA.; Santa Fe Institute, Santa Fe, NM 87501, USA.
    Wong HC; Altor Biosciences, Miramar, FL 33027, USA.
    Siliciano JD; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
    Siliciano R; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.; Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
    Safrit JT; ImmunityBio, Culver City, CA 90232, USA.
    Nixon DF; Division of Infectious Diseases, Department of Medicine, Weill Cornell Medicine, New York, NY 10065, USA.
    Soon-Shiong P; ImmunityBio, Culver City, CA 90232, USA.
    Nussenzweig M; Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.; Howard Hughes Medical Institute, The Rockefeller University, New York, NY 10065, USA.
    Whitney JB; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.; Department of Biology, Boston College, Chestnut Hill, MA 02467, USA.
    Pokaż więcej
    Źródło:
    Science (New York, N.Y.) [Science] 2024 Mar 08; Vol. 383 (6687), pp. 1104-1111. Date of Electronic Publication: 2024 Feb 29.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Anti-Retroviral Agents*/therapeutic use
    Anti-Retroviral Agents*/pharmacology
    Simian Acquired Immunodeficiency Syndrome*/drug therapy
    Simian Acquired Immunodeficiency Syndrome*/therapy
    Simian Immunodeficiency Virus*
    Recombinant Fusion Proteins*/administration & dosage
    Recombinant Fusion Proteins*/pharmacology
    Animals ; Humans ; Broadly Neutralizing Antibodies/administration & dosage ; CD8-Positive T-Lymphocytes/virology ; Immunotherapy ; Macaca mulatta ; Viral Load ; Remission Induction ; Drug Therapy, Combination
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Immunotherapeutic approach to reduce senescent cells and alleviate senescence-associated secretory phenotype in mice.
    Autorzy:
    Shrestha N; HCW Biologics Inc., Miramar, Florida, USA.
    Chaturvedi P; HCW Biologics Inc., Miramar, Florida, USA.
    Zhu X; HCW Biologics Inc., Miramar, Florida, USA.
    Dee MJ; HCW Biologics Inc., Miramar, Florida, USA.
    George V; HCW Biologics Inc., Miramar, Florida, USA.
    Janney C; HCW Biologics Inc., Miramar, Florida, USA.
    Egan JO; HCW Biologics Inc., Miramar, Florida, USA.
    Liu B; HCW Biologics Inc., Miramar, Florida, USA.
    Foster M; Division of Oncology, Washington University School of Medicine, St. Louis, Missouri, USA.
    Marsala L; Division of Oncology, Washington University School of Medicine, St. Louis, Missouri, USA.
    Wong P; Division of Oncology, Washington University School of Medicine, St. Louis, Missouri, USA.
    Cubitt CC; Division of Oncology, Washington University School of Medicine, St. Louis, Missouri, USA.
    Foltz JA; Division of Oncology, Washington University School of Medicine, St. Louis, Missouri, USA.
    Tran J; Division of Oncology, Washington University School of Medicine, St. Louis, Missouri, USA.
    Schappe T; Division of Oncology, Washington University School of Medicine, St. Louis, Missouri, USA.
    Hsiao K; Department of Pharmaceutical Sciences, Nova Southeastern University, Fort Lauderdale, Florida, USA.
    Leclerc GM; HCW Biologics Inc., Miramar, Florida, USA.
    You L; HCW Biologics Inc., Miramar, Florida, USA.
    Echeverri C; HCW Biologics Inc., Miramar, Florida, USA.
    Spanoudis C; HCW Biologics Inc., Miramar, Florida, USA.
    Carvalho A; HCW Biologics Inc., Miramar, Florida, USA.
    Kanakaraj L; HCW Biologics Inc., Miramar, Florida, USA.
    Gilkes C; HCW Biologics Inc., Miramar, Florida, USA.
    Encalada N; HCW Biologics Inc., Miramar, Florida, USA.
    Kong L; HCW Biologics Inc., Miramar, Florida, USA.
    Wang M; HCW Biologics Inc., Miramar, Florida, USA.
    Fang B; HCW Biologics Inc., Miramar, Florida, USA.
    Wang Z; HCW Biologics Inc., Miramar, Florida, USA.
    Jiao JA; HCW Biologics Inc., Miramar, Florida, USA.
    Muniz GJ; HCW Biologics Inc., Miramar, Florida, USA.
    Jeng EK; HCW Biologics Inc., Miramar, Florida, USA.
    Valdivieso N; HCW Biologics Inc., Miramar, Florida, USA.
    Li L; HCW Biologics Inc., Miramar, Florida, USA.
    Deth R; Department of Pharmaceutical Sciences, Nova Southeastern University, Fort Lauderdale, Florida, USA.
    Berrien-Elliott MM; Division of Oncology, Washington University School of Medicine, St. Louis, Missouri, USA.
    Fehniger TA; Division of Oncology, Washington University School of Medicine, St. Louis, Missouri, USA.
    Rhode PR; HCW Biologics Inc., Miramar, Florida, USA.
    Wong HC; HCW Biologics Inc., Miramar, Florida, USA.
    Pokaż więcej
    Źródło:
    Aging cell [Aging Cell] 2023 May; Vol. 22 (5), pp. e13806. Date of Electronic Publication: 2023 Mar 26.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
    MeSH Terms:
    Senescence-Associated Secretory Phenotype*
    Cellular Senescence*/genetics
    Mice ; Animals ; Aging ; Inflammation ; Immunotherapy ; Phenotype
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    A Subset of Latency-Reversing Agents Expose HIV-Infected Resting CD4+ T-Cells to Recognition by Cytotoxic T-Lymphocytes.
    Autorzy:
    Jones RB; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Cambridge, Massachusetts, United States of America.; Koch Institute for Integrative Cancer Research, MIT, Cambridge, Massachusetts, United States of America.; Department of Microbiology Immunology and Tropical Medicine, The George Washington University, Washington, D.C., United States of America.
    Mueller S; Koch Institute for Integrative Cancer Research, MIT, Cambridge, Massachusetts, United States of America.
    O'Connor R; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Cambridge, Massachusetts, United States of America.
    Rimpel K; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Cambridge, Massachusetts, United States of America.
    Sloan DD; Gilead Sciences, Foster City, California, United States of America.
    Karel D; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Cambridge, Massachusetts, United States of America.
    Wong HC; Altor BioScience Corporation, Miramar, Florida, United States of America.
    Jeng EK; Altor BioScience Corporation, Miramar, Florida, United States of America.
    Thomas AS; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Cambridge, Massachusetts, United States of America.; Department of Microbiology Immunology and Tropical Medicine, The George Washington University, Washington, D.C., United States of America.
    Whitney JB; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Cambridge, Massachusetts, United States of America.; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America.
    Lim SY; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America.
    Kovacs C; The Maple Leaf Medical Clinic, Toronto, Ontario, Canada.; Department of Medicine, University of Toronto, Toronto, Ontario, Canada.
    Benko E; The Maple Leaf Medical Clinic, Toronto, Ontario, Canada.
    Karandish S; Department of Microbiology Immunology and Tropical Medicine, The George Washington University, Washington, D.C., United States of America.
    Huang SH; Department of Microbiology Immunology and Tropical Medicine, The George Washington University, Washington, D.C., United States of America.
    Buzon MJ; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Cambridge, Massachusetts, United States of America.
    Lichterfeld M; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Cambridge, Massachusetts, United States of America.
    Irrinki A; Gilead Sciences, Foster City, California, United States of America.
    Murry JP; Gilead Sciences, Foster City, California, United States of America.
    Tsai A; Gilead Sciences, Foster City, California, United States of America.
    Yu H; Gilead Sciences, Foster City, California, United States of America.
    Geleziunas R; Gilead Sciences, Foster City, California, United States of America.
    Trocha A; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Cambridge, Massachusetts, United States of America.
    Ostrowski MA; Department of Medicine, University of Toronto, Toronto, Ontario, Canada.; Li Ka Shing Medical Institute, St. Michael's Hospital, Toronto, Ontario, Canad.
    Irvine DJ; Koch Institute for Integrative Cancer Research, MIT, Cambridge, Massachusetts, United States of America.; Howard Hughes Medical Institute, Chevy Chase, Maryland, United States of America.; Department of Biological Engineering, MIT, Cambridge, Massachusetts, United States of America.
    Walker BD; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Cambridge, Massachusetts, United States of America.; Howard Hughes Medical Institute, Chevy Chase, Maryland, United States of America.
    Pokaż więcej
    Źródło:
    PLoS pathogens [PLoS Pathog] 2016 Apr 15; Vol. 12 (4), pp. e1005545. Date of Electronic Publication: 2016 Apr 15 (Print Publication: 2016).
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Antiviral Agents/*pharmacology
    CD4-Positive T-Lymphocytes/*virology
    HIV Infections/*immunology
    Proteins/*pharmacology
    T-Lymphocytes, Cytotoxic/*immunology
    Virus Latency/*drug effects
    Enzyme-Linked Immunosorbent Assay ; Enzyme-Linked Immunospot Assay ; Flow Cytometry ; Humans ; Polymerase Chain Reaction ; Recombinant Fusion Proteins ; Virus Activation/drug effects
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
      Wyświetlanie 1-3 z 3

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