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Tytuł:
Total glucosides of paeony ameliorates oxidative stress, apoptosis and inflammatory response by regulating the Smad7‑TGF‑β pathway in allergic rhinitis.
Autorzy:
Jin Y; Department of Otolaryngology, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310000, P.R. China.
Zhang A; Department of Otolaryngology, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310000, P.R. China.
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Źródło:
Molecular medicine reports [Mol Med Rep] 2022 Mar; Vol. 25 (3). Date of Electronic Publication: 2022 Jan 14.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis/*drug effects
Glucosides/*pharmacology
Oxidative Stress/*drug effects
Paeonia/*chemistry
Plant Extracts/*pharmacology
Smad7 Protein/*metabolism
Transforming Growth Factor beta/*metabolism
Animals ; Biomarkers ; Cytokines/metabolism ; Disease Models, Animal ; Glucosides/chemistry ; Immunoglobulin E/immunology ; Immunohistochemistry ; Male ; Mice ; Plant Extracts/chemistry ; Rhinitis, Allergic/etiology ; Rhinitis, Allergic/metabolism ; Rhinitis, Allergic/pathology ; Signal Transduction
Czasopismo naukowe
Tytuł:
Curcumin Alleviates LPS-Induced Oxidative Stress, Inflammation and Apoptosis in Bovine Mammary Epithelial Cells via the NFE2L2 Signaling Pathway.
Autorzy:
Li R; Key Laboratory of Zoonosis Research, Ministry of Education, Department of Animal Science, College of Animal Sciences, Jilin University, Changchun 130062, China.
Fang H; Key Laboratory of Zoonosis Research, Ministry of Education, Department of Animal Science, College of Animal Sciences, Jilin University, Changchun 130062, China.
Shen J; Key Laboratory of Zoonosis Research, Ministry of Education, Department of Animal Science, College of Animal Sciences, Jilin University, Changchun 130062, China.
Jin Y; Key Laboratory of Zoonosis Research, Ministry of Education, Department of Animal Science, College of Animal Sciences, Jilin University, Changchun 130062, China.
Zhao Y; Key Laboratory of Zoonosis Research, Ministry of Education, Department of Animal Science, College of Animal Sciences, Jilin University, Changchun 130062, China.
Wang R; Key Laboratory of Zoonosis Research, Ministry of Education, Department of Animal Science, College of Animal Sciences, Jilin University, Changchun 130062, China.
Fu Y; Key Laboratory of Zoonosis Research, Ministry of Education, Department of Animal Science, College of Animal Sciences, Jilin University, Changchun 130062, China.
Tian Y; Key Laboratory of Zoonosis Research, Ministry of Education, Department of Animal Science, College of Animal Sciences, Jilin University, Changchun 130062, China.
Yu H; Key Laboratory of Zoonosis Research, Ministry of Education, Department of Animal Science, College of Animal Sciences, Jilin University, Changchun 130062, China.
Zhang J; Key Laboratory of Zoonosis Research, Ministry of Education, Department of Animal Science, College of Animal Sciences, Jilin University, Changchun 130062, China.
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Źródło:
Toxins [Toxins (Basel)] 2021 Mar 12; Vol. 13 (3). Date of Electronic Publication: 2021 Mar 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Anti-Inflammatory Agents/*pharmacology
Antioxidants/*pharmacology
Apoptosis/*drug effects
Curcumin/*pharmacology
Endotoxins/*toxicity
Epithelial Cells/*drug effects
Inflammation Mediators/*metabolism
Mammary Glands, Animal/*drug effects
NF-E2-Related Factor 2/*metabolism
Oxidative Stress/*drug effects
Animals ; Apoptosis Regulatory Proteins/metabolism ; Cattle ; Cell Line ; Epithelial Cells/metabolism ; Epithelial Cells/pathology ; Female ; Mammary Glands, Animal/metabolism ; Mammary Glands, Animal/pathology ; Reactive Oxygen Species/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł:
Blockage of AMPK-ULK1 pathway mediated autophagy promotes cell apoptosis to increase doxorubicin sensitivity in breast cancer (BC) cells: an in vitro study.
Autorzy:
Yu L; Medicine Department, Harbin Medical University Cancer Hospital, Haping Road No.150, Harbin, 150081, Heilongjiang, China.
Shi Q; Medicine Department, Harbin Medical University Cancer Hospital, Haping Road No.150, Harbin, 150081, Heilongjiang, China.
Jin Y; Medicine Department, Harbin Medical University Cancer Hospital, Haping Road No.150, Harbin, 150081, Heilongjiang, China.
Liu Z; Medicine Department, Harbin Medical University Cancer Hospital, Haping Road No.150, Harbin, 150081, Heilongjiang, China.
Li J; Medicine Department, Harbin Medical University Cancer Hospital, Haping Road No.150, Harbin, 150081, Heilongjiang, China.
Sun W; Medicine Department, Harbin Medical University Cancer Hospital, Haping Road No.150, Harbin, 150081, Heilongjiang, China. .
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Źródło:
BMC cancer [BMC Cancer] 2021 Feb 25; Vol. 21 (1), pp. 195. Date of Electronic Publication: 2021 Feb 25.
Typ publikacji:
Journal Article
MeSH Terms:
AMP-Activated Protein Kinases/*physiology
Apoptosis/*drug effects
Autophagy/*physiology
Autophagy-Related Protein-1 Homolog/*physiology
Breast Neoplasms/*drug therapy
Doxorubicin/*pharmacology
Intracellular Signaling Peptides and Proteins/*physiology
Adenine/analogs & derivatives ; Adenine/pharmacology ; Autophagy/drug effects ; Breast Neoplasms/pathology ; Cell Line, Tumor ; Drug Resistance, Neoplasm ; Female ; Humans ; Signal Transduction/drug effects ; Signal Transduction/physiology
Czasopismo naukowe
Tytuł:
Polydatin Protects Bovine Mammary Epithelial Cells Against Zearalenone-Induced Apoptosis By Inhibiting Oxidative Responses and Endoplasmic Reticulum Stress.
Autorzy:
Fu Y; Key Laboratory of Zoonosis Research, Department of Animal Science, College of Animal Sciences, Jilin University, Ministry of Education, Changchun 130062, China.
Jin Y; Key Laboratory of Zoonosis Research, Department of Animal Science, College of Animal Sciences, Jilin University, Ministry of Education, Changchun 130062, China.
Shan A; Institute of Animal Nutrition, Northeast Agricultural University, Harbin 150030, China.
Zhang J; Key Laboratory of Zoonosis Research, Department of Animal Science, College of Animal Sciences, Jilin University, Ministry of Education, Changchun 130062, China.
Tang H; Key Laboratory of Zoonosis Research, Department of Animal Science, College of Animal Sciences, Jilin University, Ministry of Education, Changchun 130062, China.
Shen J; Key Laboratory of Zoonosis Research, Department of Animal Science, College of Animal Sciences, Jilin University, Ministry of Education, Changchun 130062, China.
Zhou C; Key Laboratory of Zoonosis Research, Department of Animal Science, College of Animal Sciences, Jilin University, Ministry of Education, Changchun 130062, China.
Yu H; Key Laboratory of Zoonosis Research, Department of Animal Science, College of Animal Sciences, Jilin University, Ministry of Education, Changchun 130062, China.
Fang H; Key Laboratory of Zoonosis Research, Department of Animal Science, College of Animal Sciences, Jilin University, Ministry of Education, Changchun 130062, China.
Zhao Y; Key Laboratory of Zoonosis Research, Department of Animal Science, College of Animal Sciences, Jilin University, Ministry of Education, Changchun 130062, China.
Wang J; Key Laboratory of Zoonosis Research, Department of Animal Science, College of Animal Sciences, Jilin University, Ministry of Education, Changchun 130062, China.
Tian Y; Key Laboratory of Zoonosis Research, Department of Animal Science, College of Animal Sciences, Jilin University, Ministry of Education, Changchun 130062, China.
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Źródło:
Toxins [Toxins (Basel)] 2021 Feb 05; Vol. 13 (2). Date of Electronic Publication: 2021 Feb 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antioxidants/*pharmacology
Apoptosis/*drug effects
Endoplasmic Reticulum Stress/*drug effects
Epithelial Cells/*drug effects
Glucosides/*pharmacology
Mammary Glands, Animal/*drug effects
Oxidative Stress/*drug effects
Stilbenes/*pharmacology
Zearalenone/*toxicity
Animals ; Apoptosis Regulatory Proteins/metabolism ; Cattle ; Cell Line ; Cytoprotection ; Epithelial Cells/metabolism ; Epithelial Cells/pathology ; Female ; Mammary Glands, Animal/metabolism ; Mammary Glands, Animal/pathology ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł:
Intrinsic apoptosis and cytokine induction regulated in human tonsillar epithelial cells infected with enterovirus A71.
Autorzy:
Sun M; Medical School and Jiangsu Provincial Key Laboratory of Medicine, Nanjing University, Nanjing, China.; Nanjing Children's Hospital, Nanjing Medical University, Nanjing, China.
Yan K; Nanjing Children's Hospital, Nanjing Medical University, Nanjing, China.
Wang C; Clinical Medical College, Xi'an Medical University, Xi'an, China.
Xing J; Nanjing Children's Hospital, Nanjing Medical University, Nanjing, China.
Duan Z; National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Jin Y; Medical School and Jiangsu Provincial Key Laboratory of Medicine, Nanjing University, Nanjing, China.; Nanjing Children's Hospital, Nanjing Medical University, Nanjing, China.
Cardona CJ; Department of Veterinary Biomedical Sciences, College of Veterinary Medicine, University of Minnesota at Twin Cities, St. Paul, Minnesota, United States of America.
Xing Z; Medical School and Jiangsu Provincial Key Laboratory of Medicine, Nanjing University, Nanjing, China.; Department of Veterinary Biomedical Sciences, College of Veterinary Medicine, University of Minnesota at Twin Cities, St. Paul, Minnesota, United States of America.
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Źródło:
PloS one [PLoS One] 2021 Jan 22; Vol. 16 (1), pp. e0245529. Date of Electronic Publication: 2021 Jan 22 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*
Cytokines/*metabolism
Enterovirus A, Human/*physiology
Epithelial Cells/*pathology
Epithelial Cells/*virology
Palatine Tonsil/*pathology
Cell Line ; Cytochromes c/metabolism ; Gene Expression Regulation ; Humans ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Virus Replication
Czasopismo naukowe
Tytuł:
Effects of the E1 activating enzyme UBA2 on porcine oocyte maturation, apoptosis, and embryonic development in vitro.
Autorzy:
Xu D; Department of Animal Science, College of Agriculture, Yanbian University, Yanji, China.; Jilin Medical University, Jilin, China.
Bi J; College of Life Sciences, Xiamen University, Fujian, China.
Guan Y; College of Life Sciences, Xiamen University, Fujian, China.
Luo X; Department of Animal Science, College of Agriculture, Yanbian University, Yanji, China.
Chen X; Department of Animal Science, College of Agriculture, Yanbian University, Yanji, China.
Lv Y; Department of Animal Science, College of Agriculture, Yanbian University, Yanji, China.
Jin Y; Department of Animal Science, College of Agriculture, Yanbian University, Yanji, China.
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Źródło:
Animal science journal = Nihon chikusan Gakkaiho [Anim Sci J] 2021 Jan-Dec; Vol. 92 (1), pp. e13548.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis/*drug effects
Apoptosis/*genetics
Embryonic Development/*drug effects
Embryonic Development/*genetics
Gene Expression/*genetics
Gene Expression Regulation, Developmental/*drug effects
Oocytes/*growth & development
Oogenesis/*drug effects
Oogenesis/*genetics
SUMO-1 Protein/*genetics
SUMO-1 Protein/*metabolism
Ubiquitin-Activating Enzymes/*pharmacology
Animals ; Cell Survival/drug effects ; Cell Survival/genetics ; Embryo Culture Techniques/veterinary ; Female ; Fertilization in Vitro ; In Vitro Oocyte Maturation Techniques/veterinary ; Pregnancy ; Swine
Czasopismo naukowe
Tytuł:
B7-H3 participates in human salivary gland epithelial cells apoptosis through NF-κB pathway in primary Sjögren's syndrome.
Autorzy:
Li P; Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, 20th Xisi Road, Nantong, 226001, Jiangsu, People's Republic of China.
Yang Y; Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, 20th Xisi Road, Nantong, 226001, Jiangsu, People's Republic of China.
Jin Y; Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, 20th Xisi Road, Nantong, 226001, Jiangsu, People's Republic of China.
Zhao R; Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, 20th Xisi Road, Nantong, 226001, Jiangsu, People's Republic of China.
Dong C; Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, 20th Xisi Road, Nantong, 226001, Jiangsu, People's Republic of China.
Zheng W; Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, 20th Xisi Road, Nantong, 226001, Jiangsu, People's Republic of China.
Zhang T; Key Laboratory of Neuroregeneration, Nantong University, Nantong, 226001, Jiangsu, People's Republic of China.
Li J; Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, 20th Xisi Road, Nantong, 226001, Jiangsu, People's Republic of China. .; Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong, 226001, Jiangsu, People's Republic of China. .
Gu Z; Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, 20th Xisi Road, Nantong, 226001, Jiangsu, People's Republic of China. .; Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong, 226001, Jiangsu, People's Republic of China. .
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Źródło:
Journal of translational medicine [J Transl Med] 2019 Aug 14; Vol. 17 (1), pp. 268. Date of Electronic Publication: 2019 Aug 14.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*
B7 Antigens/*metabolism
Epithelial Cells/*metabolism
Epithelial Cells/*pathology
NF-kappa B/*metabolism
Salivary Glands/*pathology
Sjogren's Syndrome/*metabolism
Sjogren's Syndrome/*pathology
Aquaporin 5/metabolism ; B7 Antigens/blood ; Case-Control Studies ; Cell Proliferation ; Humans ; Middle Aged ; Sjogren's Syndrome/blood
Czasopismo naukowe
Tytuł:
Knockdown expression of MECR, a novel gene of mitochondrial FAS II inhibits growth and colony-formation, promotes apoptosis of hepatocelluar carcinoma cells.
Autorzy:
Cai Y; Department of Biliary Surgery, West China Hospital, Sichuan University.
Lin Y; Department of Biliary Surgery, West China Hospital, Sichuan University.
Xiong X; Department of Biliary Surgery, West China Hospital, Sichuan University.
Lu J; Department of Biliary Surgery, West China Hospital, Sichuan University.
Zhou R; Department of Biliary Surgery, West China Hospital, Sichuan University.
Jin Y; Department of Biliary Surgery, West China Hospital, Sichuan University.
You Z; Department of Biliary Surgery, West China Hospital, Sichuan University.
Ye H; Department of Biliary Surgery, West China Hospital, Sichuan University.
Li F; Department of Biliary Surgery, West China Hospital, Sichuan University.
Cheng N; Department of Biliary Surgery, West China Hospital, Sichuan University.
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Źródło:
Bioscience trends [Biosci Trends] 2019 Jul 22; Vol. 13 (3), pp. 234-244. Date of Electronic Publication: 2019 Jun 10.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis/*physiology
Carcinoma, Hepatocellular/*metabolism
Cell Cycle/*physiology
Liver Neoplasms/*metabolism
Oxidoreductases Acting on CH-CH Group Donors/*metabolism
Apoptosis/genetics ; Blotting, Western ; Carcinoma, Hepatocellular/genetics ; Cell Cycle/genetics ; Cell Line ; Cell Line, Tumor ; Cell Proliferation/genetics ; Cell Proliferation/physiology ; Gene Expression Regulation, Neoplastic/genetics ; Gene Expression Regulation, Neoplastic/physiology ; Humans ; Liver Neoplasms/genetics ; Mitochondria/genetics ; Mitochondria/metabolism ; Oxidoreductases Acting on CH-CH Group Donors/genetics ; Reverse Transcriptase Polymerase Chain Reaction ; Signal Transduction/genetics ; Signal Transduction/physiology
Czasopismo naukowe
Tytuł:
DDAH1 regulates apoptosis and angiogenesis in human fetal pulmonary microvascular endothelial cells.
Autorzy:
Trittmann JK; Pulmonary Hypertension Group, Center for Perinatal Research, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio.; Department of Pediatrics, The Ohio State University, Columbus, Ohio.
Almazroue H; Pulmonary Hypertension Group, Center for Perinatal Research, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio.
Jin Y; Pulmonary Hypertension Group, Center for Perinatal Research, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio.
Nelin LD; Pulmonary Hypertension Group, Center for Perinatal Research, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio.; Department of Pediatrics, The Ohio State University, Columbus, Ohio.
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Źródło:
Physiological reports [Physiol Rep] 2019 Jul; Vol. 7 (12), pp. e14150.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Amidohydrolases/*physiology
Apoptosis/*physiology
Lung/*blood supply
Neovascularization, Physiologic/*physiology
Amidohydrolases/genetics ; Caspase 3/metabolism ; Caspase 8/metabolism ; Endothelial Cells/cytology ; Enzyme Activation/physiology ; Gene Knockdown Techniques ; Humans ; Lung/embryology ; Microvessels/cytology ; Nitric Oxide/biosynthesis ; Nitric Oxide Donors/pharmacology ; RNA, Small Interfering/genetics
Czasopismo naukowe
Tytuł:
Moderate hypothermia inhibits microglial activation after traumatic brain injury by modulating autophagy/apoptosis and the MyD88-dependent TLR4 signaling pathway.
Autorzy:
Zhang F; Department of Neurosurgery, Ren-Ji Hospital, School of Medicine, Shanghai Jiao Tong University, No. 160 Pujian Road, Shanghai, 200127, People's Republic of China.
Dong H; Department of Anesthesiology, Ren-Ji Hospital, School of Medicine, Shanghai Jiao Tong University, No. 160 Pujian Road, Shanghai, 200127, People's Republic of China.
Lv T; Department of Neurosurgery, Ren-Ji Hospital, School of Medicine, Shanghai Jiao Tong University, No. 160 Pujian Road, Shanghai, 200127, People's Republic of China.
Jin K; Department of Neurosurgery, Ren-Ji Hospital, School of Medicine, Shanghai Jiao Tong University, No. 160 Pujian Road, Shanghai, 200127, People's Republic of China.
Jin Y; Department of Neurosurgery, Ren-Ji Hospital, School of Medicine, Shanghai Jiao Tong University, No. 160 Pujian Road, Shanghai, 200127, People's Republic of China. .
Zhang X; Department of Neurosurgery, Ren-Ji Hospital, School of Medicine, Shanghai Jiao Tong University, No. 160 Pujian Road, Shanghai, 200127, People's Republic of China. .
Jiang J; Department of Neurosurgery, Ren-Ji Hospital, School of Medicine, Shanghai Jiao Tong University, No. 160 Pujian Road, Shanghai, 200127, People's Republic of China.
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Źródło:
Journal of neuroinflammation [J Neuroinflammation] 2018 Sep 20; Vol. 15 (1), pp. 273. Date of Electronic Publication: 2018 Sep 20.
Typ publikacji:
Journal Article
MeSH Terms:
Hypothermia, Induced*
Apoptosis/*physiology
Autophagy/*physiology
Brain Injuries, Traumatic/*therapy
Microglia/*metabolism
Myeloid Differentiation Factor 88/*metabolism
Toll-Like Receptor 4/*physiology
Animals ; Brain/pathology ; Brain Injuries, Traumatic/pathology ; Calcium-Binding Proteins/metabolism ; Caspase 3/metabolism ; Cytokines/genetics ; Cytokines/metabolism ; Disease Models, Animal ; Functional Laterality ; Gene Expression Regulation/physiology ; Male ; Microfilament Proteins/metabolism ; Microtubule-Associated Proteins/metabolism ; Rats ; Rats, Sprague-Dawley ; Signal Transduction/drug effects ; Signal Transduction/physiology
Czasopismo naukowe
Tytuł:
Knockdown of peroxiredoxin V increases glutamate‑induced apoptosis in HT22 hippocampal neuron cells.
Autorzy:
Shen GN; Department of Disease Model Animal Research Center, College of Life Science and Technology, Heilongjiang Bayi Agricultural University, Daqing, Heilongjiang 163319, P.R. China.
Liu L; Department of Disease Model Animal Research Center, College of Life Science and Technology, Heilongjiang Bayi Agricultural University, Daqing, Heilongjiang 163319, P.R. China.
Feng L; Pharmaron Beijing Co., Ltd., Beijing 100176, P.R. China.
Jin Y; Laboratory of Anatomy and Histology, Yanbian University Health Science Center, Yanji, Jilin 133000, P.R. China.
Jin MH; Department of Disease Model Animal Research Center, College of Life Science and Technology, Heilongjiang Bayi Agricultural University, Daqing, Heilongjiang 163319, P.R. China.
Han YH; Department of Disease Model Animal Research Center, College of Life Science and Technology, Heilongjiang Bayi Agricultural University, Daqing, Heilongjiang 163319, P.R. China.
Jin CH; Department of Disease Model Animal Research Center, College of Life Science and Technology, Heilongjiang Bayi Agricultural University, Daqing, Heilongjiang 163319, P.R. China.
Jin YZ; Laboratory of Anatomy and Histology, Yanbian University Health Science Center, Yanji, Jilin 133000, P.R. China.
Lee DS; Laboratory of Molecular Neurobiology, School of Life Sciences, KNU Creative Bio Research Group (BK21 Plus Project), Kyungpook National University, Daegu 41566, Republic of Korea.
Kwon TH; Laboratory of Animal Genetic Engineering and Stem Cell Biology, Subtropical/Tropical Organism Gene Bank, Jeju National University, Jeju, Jeju 63243, Republic of Korea.
Cui YD; Department of Disease Model Animal Research Center, College of Life Science and Technology, Heilongjiang Bayi Agricultural University, Daqing, Heilongjiang 163319, P.R. China.
Sun HN; Department of Disease Model Animal Research Center, College of Life Science and Technology, Heilongjiang Bayi Agricultural University, Daqing, Heilongjiang 163319, P.R. China.
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Źródło:
Molecular medicine reports [Mol Med Rep] 2018 Jun; Vol. 17 (6), pp. 7827-7834. Date of Electronic Publication: 2018 Mar 29.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis/*genetics
Glutamic Acid/*metabolism
Peroxiredoxins/*genetics
Pyramidal Cells/*metabolism
Animals ; Apoptosis/drug effects ; Apoptosis Inducing Factor/metabolism ; Cell Line, Tumor ; Extracellular Signal-Regulated MAP Kinases/metabolism ; Gene Knockout Techniques ; Glutamic Acid/pharmacology ; Mice ; Pyramidal Cells/drug effects ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł:
Hedyotis diffusa Willd inhibits proliferation and induces apoptosis of 5‑FU resistant colorectal cancer cells by regulating the PI3K/AKT signaling pathway.
Autorzy:
Li Q; Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, P.R. China.
Lai Z; Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, P.R. China.
Yan Z; Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, P.R. China.
Peng J; Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, P.R. China.
Jin Y; Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, P.R. China.
Wei L; Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, P.R. China.
Lin J; Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, P.R. China.
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Źródło:
Molecular medicine reports [Mol Med Rep] 2018 Jan; Vol. 17 (1), pp. 358-365. Date of Electronic Publication: 2017 Oct 26.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents, Phytogenic/*pharmacology
Apoptosis/*drug effects
Colorectal Neoplasms/*metabolism
Fluorouracil/*pharmacology
Hedyotis/*chemistry
Phosphatidylinositol 3-Kinase/*metabolism
Plant Extracts/*pharmacology
Proto-Oncogene Proteins c-akt/*metabolism
Apoptosis Regulatory Proteins/genetics ; Apoptosis Regulatory Proteins/metabolism ; Cell Survival/drug effects ; Colorectal Neoplasms/genetics ; Colorectal Neoplasms/pathology ; Drug Synergism ; Gene Expression Regulation, Neoplastic/drug effects ; Humans
Czasopismo naukowe
Tytuł:
Knockdown of XBP1 by RNAi in Mouse Granulosa Cells Promotes Apoptosis, Inhibits Cell Cycle, and Decreases Estradiol Synthesis.
Autorzy:
Wang N; Key Laboratory of Animal Biotechnology of the Ministry of Agriculture, Northwest Agriculture and Forestry University, Yangling 712100, China. .
Zhao F; Key Laboratory of Animal Biotechnology of the Ministry of Agriculture, Northwest Agriculture and Forestry University, Yangling 712100, China. .
Lin P; Key Laboratory of Animal Biotechnology of the Ministry of Agriculture, Northwest Agriculture and Forestry University, Yangling 712100, China. .
Zhang G; Key Laboratory of Animal Biotechnology of the Ministry of Agriculture, Northwest Agriculture and Forestry University, Yangling 712100, China. .
Tang K; Key Laboratory of Animal Biotechnology of the Ministry of Agriculture, Northwest Agriculture and Forestry University, Yangling 712100, China. .
Wang A; College of Veterinary Medicine, Northwest Agriculture and Forestry University, Yangling 712100, China. .
Jin Y; Key Laboratory of Animal Biotechnology of the Ministry of Agriculture, Northwest Agriculture and Forestry University, Yangling 712100, China. .
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2017 May 29; Vol. 18 (6). Date of Electronic Publication: 2017 May 29.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis/*physiology
Cell Cycle/*physiology
Estradiol/*metabolism
Granulosa Cells/*cytology
Granulosa Cells/*metabolism
X-Box Binding Protein 1/*metabolism
Animals ; Apoptosis/genetics ; Cell Cycle/genetics ; Cell Proliferation/genetics ; Cell Proliferation/physiology ; Female ; Mice ; RNA Interference/physiology ; X-Box Binding Protein 1/deficiency ; X-Box Binding Protein 1/genetics
Czasopismo naukowe
Tytuł:
An arginase-1 SNP that protects against the development of pulmonary hypertension in bronchopulmonary dysplasia enhances NO-mediated apoptosis in lymphocytes.
Autorzy:
Trittmann JK; Pulmonary Hypertension Group, Center for Perinatal Research, The Ohio State University, Columbus, Ohio .; Department of Pediatrics, The Ohio State University, Columbus, Ohio.
Jin Y; Pulmonary Hypertension Group, Center for Perinatal Research, The Ohio State University, Columbus, Ohio.
Chicoine LG; Pulmonary Hypertension Group, Center for Perinatal Research, The Ohio State University, Columbus, Ohio.; Department of Pediatrics, The Ohio State University, Columbus, Ohio.; Center for Gene Therapy, The Research Institute at Nationwide Children's Hospital, The Ohio State University, Columbus, Ohio.
Liu Y; Pulmonary Hypertension Group, Center for Perinatal Research, The Ohio State University, Columbus, Ohio.; Department of Pediatrics, The Ohio State University, Columbus, Ohio.
Chen B; Pulmonary Hypertension Group, Center for Perinatal Research, The Ohio State University, Columbus, Ohio.; Department of Pediatrics, The Ohio State University, Columbus, Ohio.
Nelin LD; Pulmonary Hypertension Group, Center for Perinatal Research, The Ohio State University, Columbus, Ohio.; Department of Pediatrics, The Ohio State University, Columbus, Ohio.
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Źródło:
Physiological reports [Physiol Rep] 2016 Nov; Vol. 4 (22).
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis*
Arginase/*metabolism
Bronchopulmonary Dysplasia/*complications
Hypertension, Pulmonary/*prevention & control
Lymphocytes/*pathology
Nitric Oxide/*metabolism
Polymorphism, Single Nucleotide/*genetics
Arginine ; Bronchopulmonary Dysplasia/physiopathology ; Caspase 3/metabolism ; Cohort Studies ; Humans ; Hypertension, Pulmonary/etiology ; Hypertension, Pulmonary/physiopathology ; Infant, Newborn ; Lymphocytes/metabolism ; Nitric Oxide Synthase/metabolism ; Oxygen/metabolism ; Urea/metabolism
Czasopismo naukowe
Tytuł:
Intestinal injury following liver transplantation was mediated by TLR4/NF-κB activation-induced cell apoptosis.
Autorzy:
Yuan DD; Department of Anesthesiology, The Third Affiliated Hospital of Sun Yat‑sen University, Guangzhou, Guangdong 510630, P.R. China.
Chi XJ; Department of Anesthesiology, The Third Affiliated Hospital of Sun Yat‑sen University, Guangzhou, Guangdong 510630, P.R. China.
Jin Y; Department of Pathology, The Third Affiliated Hospital of Sun Yat‑sen University, Guangzhou, Guangdong 510630, P.R. China.
Li X; Department of Thyroid and Breast Surgery, The Third Affiliated Hospital of Sun Yat‑sen University, Guangzhou, Guangdong 510630, P.R. China.
Ge M; Department of Anesthesiology, The Third Affiliated Hospital of Sun Yat‑sen University, Guangzhou, Guangdong 510630, P.R. China.
Gao WL; Department of Anesthesiology, The Third Affiliated Hospital of Sun Yat‑sen University, Guangzhou, Guangdong 510630, P.R. China.
Guan JQ; Department of Anesthesiology, The Third Affiliated Hospital of Sun Yat‑sen University, Guangzhou, Guangdong 510630, P.R. China.
Zhang AL; Department of Anesthesiology, The Third Affiliated Hospital of Sun Yat‑sen University, Guangzhou, Guangdong 510630, P.R. China.
Hei ZQ; Department of Anesthesiology, The Third Affiliated Hospital of Sun Yat‑sen University, Guangzhou, Guangdong 510630, P.R. China.
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Źródło:
Molecular medicine reports [Mol Med Rep] 2016 Feb; Vol. 13 (2), pp. 1525-32. Date of Electronic Publication: 2015 Dec 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis/*genetics
NF-kappa B/*biosynthesis
Systemic Inflammatory Response Syndrome/*genetics
Toll-Like Receptor 4/*biosynthesis
Animals ; Caspase 3/biosynthesis ; Endotoxins/metabolism ; Humans ; Intestines/drug effects ; Intestines/injuries ; Intestines/pathology ; Liver Transplantation/adverse effects ; NF-kappa B/genetics ; Postoperative Complications/genetics ; Postoperative Complications/pathology ; Rats ; Systemic Inflammatory Response Syndrome/pathology ; Toll-Like Receptor 4/genetics
Czasopismo naukowe
Tytuł:
Osteoblast-induced osteoclast apoptosis by fas ligand/FAS pathway is required for maintenance of bone mass.
Autorzy:
Wang L; State Key Laboratory of Military Stomatology, Center for Tissue Engineering, School of Stomatology, The Fourth Military Medical University, Xi'an, Shaanxi 710032, China.; State Key Laboratory of Military Stomatology, Department of Oral and Maxillofacial Surgery, School of Stomatology, The Fourth Military Medical University, Xi'an, Shaanxi 710032, China.
Liu S; State Key Laboratory of Military Stomatology, Center for Tissue Engineering, School of Stomatology, The Fourth Military Medical University, Xi'an, Shaanxi 710032, China.; Research and Development Center for Tissue Engineering, The Fourth Military Medical University, Xi'an, Shaanxi 710032, China.
Zhao Y; State Key Laboratory of Military Stomatology, Center for Tissue Engineering, School of Stomatology, The Fourth Military Medical University, Xi'an, Shaanxi 710032, China.
Liu D; Department of Anatomy and Cell Biology, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Liu Y; Department of Anatomy and Cell Biology, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Chen C; Department of Anatomy and Cell Biology, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Karray S; INSERM U753, Institut Gustave Roussy, Villejuif Cedex, France.
Shi S; State Key Laboratory of Military Stomatology, Center for Tissue Engineering, School of Stomatology, The Fourth Military Medical University, Xi'an, Shaanxi 710032, China.; Research and Development Center for Tissue Engineering, The Fourth Military Medical University, Xi'an, Shaanxi 710032, China.; Department of Anatomy and Cell Biology, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Jin Y; State Key Laboratory of Military Stomatology, Center for Tissue Engineering, School of Stomatology, The Fourth Military Medical University, Xi'an, Shaanxi 710032, China.; Research and Development Center for Tissue Engineering, The Fourth Military Medical University, Xi'an, Shaanxi 710032, China.
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Źródło:
Cell death and differentiation [Cell Death Differ] 2015 Oct; Vol. 22 (10), pp. 1654-64. Date of Electronic Publication: 2015 Mar 06.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*
Bone Density/*physiology
Bone and Bones/*physiology
Fas Ligand Protein/*physiology
Osteoblasts/*metabolism
Osteoclasts/*metabolism
Osteoporosis/*physiopathology
Animals ; Bone and Bones/metabolism ; Disease Models, Animal ; Female ; Mice ; NF-kappa B p50 Subunit/metabolism ; Signal Transduction ; Tumor Necrosis Factor-alpha/physiology ; fas Receptor/metabolism
Czasopismo naukowe
Tytuł:
Seminal plasma leptin and spermatozoon apoptosis in patients with varicocele and leucocytospermia.
Autorzy:
Wang H; Department of Urology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai Institute of Andrology, Shanghai, China.
Lv Y; Department of Urology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai Institute of Andrology, Shanghai, China.
Hu K; Department of Urology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai Institute of Andrology, Shanghai, China.
Feng T; Department of Urology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai Institute of Andrology, Shanghai, China.
Jin Y; Department of Urology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai Institute of Andrology, Shanghai, China.
Wang Y; Department of Urology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai Institute of Andrology, Shanghai, China.
Huang Y; Department of Urology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai Institute of Andrology, Shanghai, China.
Chen B; Department of Urology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai Institute of Andrology, Shanghai, China.
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Źródło:
Andrologia [Andrologia] 2015 Aug; Vol. 47 (6), pp. 655-61. Date of Electronic Publication: 2014 Aug 01.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis/*physiology
Leptin/*analysis
Leukocytes/*physiology
Semen/*chemistry
Spermatozoa/*physiology
Adult ; Case-Control Studies ; Humans ; Male ; Reactive Oxygen Species/analysis ; Semen/cytology ; Tumor Necrosis Factor-alpha/analysis ; Varicocele
Czasopismo naukowe
Tytuł:
Aluminum and benzo[a]pyrene co-operate to induce neuronal apoptosis in vitro.
Autorzy:
Jinzhu Y; Department of Neurosurgery, Datong Coal Mine General Hospital, I Wei Qi Lu, Dotango 037003; 2. Department of Occupational Health, Institute of Preventive Medicine, Shanxi Medical University, China.
Qinli Z
Jin Y
Pan K
Jianjun H
Qiao N
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Źródło:
The Journal of toxicological sciences [J Toxicol Sci] 2015 Jun; Vol. 40 (3), pp. 365-73.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Aluminum Compounds/*adverse effects
Apoptosis/*drug effects
Benzopyrenes/*adverse effects
Environmental Pollutants/*adverse effects
Neurons/*drug effects
Neurons/*pathology
Animals ; Caspase 3/metabolism ; Cells, Cultured ; Drug Synergism ; Microscopy, Electron, Transmission ; Microscopy, Fluorescence ; Neurons/enzymology ; Neurons/ultrastructure ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł:
Verbascoside promotes apoptosis by regulating HIPK2-p53 signaling in human colorectal cancer.
Autorzy:
Zhou L
Feng Y
Jin Y
Liu X
Sui H
Chai N
Chen X
Liu N
Ji Q
Wang Y
Li Q; Department of Medical Oncology, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China. .
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Źródło:
BMC cancer [BMC Cancer] 2014 Oct 05; Vol. 14, pp. 747. Date of Electronic Publication: 2014 Oct 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis/*drug effects
Carrier Proteins/*metabolism
Colorectal Neoplasms/*metabolism
Glucosides/*pharmacology
Phenols/*pharmacology
Protein Serine-Threonine Kinases/*metabolism
Signal Transduction/*drug effects
Tumor Suppressor Protein p53/*metabolism
Adult ; Aged ; Animals ; Antineoplastic Agents, Phytogenic/pharmacology ; Apoptosis/genetics ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Colorectal Neoplasms/genetics ; Colorectal Neoplasms/pathology ; Disease Models, Animal ; Female ; Gene Expression ; Heterografts ; Humans ; Male ; Mice ; Middle Aged ; Neoplasm Grading ; Neoplasm Metastasis ; Neoplasm Staging
Czasopismo naukowe
Tytuł:
Flotillin-2 modulates fas signaling mediated apoptosis after hyperoxia in lung epithelial cells.
Autorzy:
Wei S; Division of Pulmonary and Critical Care, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America ; Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou, China.
Moon HG
Zheng Y
Liang X
An CH
Jin Y
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Źródło:
PloS one [PLoS One] 2013 Oct 18; Vol. 8 (10), pp. e77519. Date of Electronic Publication: 2013 Oct 18 (Print Publication: 2013).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis/*physiology
Epithelial Cells/*metabolism
Hyperoxia/*metabolism
Lung/*metabolism
Membrane Proteins/*metabolism
Signal Transduction/*physiology
fas Receptor/*metabolism
Animals ; Caspase 3/metabolism ; Caspase 8/metabolism ; Cell Death/physiology ; Cell Line ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; Mitochondria/metabolism
Czasopismo naukowe

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