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Tytuł :
Calcium induces increases in peroxisome proliferator-activated receptor gamma coactivator-1alpha and mitochondrial biogenesis by a pathway leading to p38 mitogen-activated protein kinase activation.
Autorzy :
Wright DC; Department of Medicine, Washington University School of Medicine, St. Louis, Missouri 63110, USA.
Geiger PC
Han DH
Jones TE
Holloszy JO
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2007 Jun 29; Vol. 282 (26), pp. 18793-9. Date of Electronic Publication: 2007 May 07.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Calcium/*metabolism
Heat-Shock Proteins/*metabolism
Mitochondria/*metabolism
PPAR gamma/*metabolism
Transcription Factors/*metabolism
p38 Mitogen-Activated Protein Kinases/*metabolism
Actins/metabolism ; Activating Transcription Factor 2/metabolism ; Adaptation, Physiological/physiology ; Animals ; Biomarkers/metabolism ; Calcium-Calmodulin-Dependent Protein Kinase Type 2 ; Calcium-Calmodulin-Dependent Protein Kinases/metabolism ; Cyclic AMP-Dependent Protein Kinases/metabolism ; Cytosol/metabolism ; Enzyme Inhibitors/pharmacology ; Imidazoles/pharmacology ; Male ; Muscle, Skeletal/metabolism ; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha ; Phosphorylation ; Pyridines/pharmacology ; Rats ; Rats, Wistar ; Signal Transduction/drug effects ; Signal Transduction/physiology ; p38 Mitogen-Activated Protein Kinases/antagonists & inhibitors
Czasopismo naukowe
Tytuł :
Exercise-induced mitochondrial biogenesis begins before the increase in muscle PGC-1alpha expression.
Autorzy :
Wright DC; Department of Medicine, Washington University School of Medicine, St. Louis, Missouri 63110, USA.
Han DH
Garcia-Roves PM
Geiger PC
Jones TE
Holloszy JO
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2007 Jan 05; Vol. 282 (1), pp. 194-9. Date of Electronic Publication: 2006 Nov 12.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Muscles/*metabolism
RNA-Binding Proteins/*metabolism
Transcription Factors/*metabolism
Animals ; Blotting, Western ; Cell Nucleus/metabolism ; Chromatin/metabolism ; Cytosol/metabolism ; DNA Primers/chemistry ; Male ; Mitochondria/metabolism ; Muscle, Skeletal/metabolism ; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha ; Promoter Regions, Genetic ; RNA, Messenger/metabolism ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Suspected DLIS interference in the dimension DGNA digoxin assay method and the clinical application of the revised digoxin target range.
Autorzy :
Morris RG; Department of Cardiology and Clinical Pharmacology, The Queen Elizabeth Hospital, South Australia.
Jones TE
Goldsworthy SJ
Wagner TJ
Ho H
Horowitz JD
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Źródło :
Therapeutic drug monitoring [Ther Drug Monit] 2006 Jun; Vol. 28 (3), pp. 454-7.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Cardenolides/*blood
Cardiotonic Agents/*blood
Digoxin/*blood
Saponins/*blood
Aged ; Cardiotonic Agents/therapeutic use ; Digoxin/therapeutic use ; Drug Monitoring ; Female ; Heart Failure/drug therapy ; Humans ; Immunoassay
Czasopismo naukowe
Tytuł :
Chronic kidney disease and automatic reporting of estimated glomerular filtration rate.
Autorzy :
Jones TE
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Źródło :
The Medical journal of Australia [Med J Aust] 2006 Jan 02; Vol. 184 (1), pp. 42; author reply 43.
Typ publikacji :
Comment; Letter
MeSH Terms :
Algorithms*
Glomerular Filtration Rate*
Kidney Failure, Chronic/*diagnosis
Australia ; Creatinine/blood ; Dose-Response Relationship, Drug ; Humans ; Kidney/metabolism ; Kidney Failure, Chronic/blood ; Reproducibility of Results
Opinia redakcyjna
Tytuł :
Calcineurin does not mediate exercise-induced increase in muscle GLUT4.
Autorzy :
Garcia-Roves PM; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.
Jones TE
Otani K
Han DH
Holloszy JO
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Źródło :
Diabetes [Diabetes] 2005 Mar; Vol. 54 (3), pp. 624-8.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Calcineurin/*physiology
Gene Expression Regulation/*physiology
Monosaccharide Transport Proteins/*biosynthesis
Muscle Proteins/*biosynthesis
Muscle, Skeletal/*metabolism
Physical Exertion/*physiology
Adaptation, Physiological ; Animals ; Calcineurin Inhibitors ; Cyclosporine/pharmacology ; DNA-Binding Proteins/biosynthesis ; Gene Expression Regulation/drug effects ; Glucose Transporter Type 4 ; Hexokinase/biosynthesis ; MEF2 Transcription Factors ; Male ; Muscle, Skeletal/drug effects ; Muscle, Skeletal/physiology ; Myogenic Regulatory Factors ; Rats ; Rats, Wistar ; Transcription Factors/biosynthesis
Czasopismo naukowe
Tytuł :
Pharmacoeconomics of low-molecular-weight heparins: limitations of studies comparing them to unfractionated heparin.
Autorzy :
Jones TE; The Queen Elizabeth Hospital, Department of Pharmacy, Woodville South, SA 5011, Australia. />Smith BJ
Polasek JF
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Źródło :
Expert opinion on pharmacotherapy [Expert Opin Pharmacother] 2004 Sep; Vol. 5 (9), pp. 1887-97.
Typ publikacji :
Comparative Study; Journal Article; Review
MeSH Terms :
Heparin/*economics
Heparin, Low-Molecular-Weight/*economics
Cost-Benefit Analysis ; Drug Costs ; Drug Monitoring/economics ; Heparin/adverse effects ; Heparin/therapeutic use ; Heparin, Low-Molecular-Weight/adverse effects ; Heparin, Low-Molecular-Weight/therapeutic use ; Humans ; Thrombocytopenia/chemically induced ; Thrombocytopenia/economics ; Thromboembolism/drug therapy ; Thromboembolism/economics ; Thromboembolism/prevention & control
Czasopismo naukowe
Tytuł :
Concentration-time profile for perhexiline and hydroxyperhexiline in patients at steady state.
Autorzy :
Jones TE; Departments of Pharmacy, Clinical Pharmacology and Cardiology, The Queen Elizabeth Hospital and Health Service, Woodville South, South Australia 5011. />Morris RG
Horowitz JD
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Źródło :
British journal of clinical pharmacology [Br J Clin Pharmacol] 2004 Mar; Vol. 57 (3), pp. 263-9.
Typ publikacji :
Journal Article
MeSH Terms :
Angina Pectoris/*drug therapy
Calcium Channel Blockers/*pharmacokinetics
Perhexiline/*pharmacokinetics
Vasodilator Agents/*pharmacokinetics
Aged ; Aged, 80 and over ; Angina Pectoris/metabolism ; Female ; Humans ; Male
Czasopismo naukowe
Tytuł :
Prevention of glycogen supercompensation prolongs the increase in muscle GLUT4 after exercise.
Autorzy :
Garcia-Roves PM; Department of Internal Medicine, Washington University School of Medicine, 4566 Scott Avenue, St. Louis, MO 63110, USA.
Han DH
Song Z
Jones TE
Hucker KA
Holloszy JO
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Źródło :
American journal of physiology. Endocrinology and metabolism [Am J Physiol Endocrinol Metab] 2003 Oct; Vol. 285 (4), pp. E729-36. Date of Electronic Publication: 2003 Jun 10.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Muscle Proteins*
Deoxyglucose/*metabolism
Dietary Carbohydrates/*pharmacology
Glycogen/*physiology
Monosaccharide Transport Proteins/*biosynthesis
Muscle, Skeletal/*physiology
Physical Conditioning, Animal/*physiology
Animals ; Fasting/physiology ; Forelimb/drug effects ; Forelimb/metabolism ; Forelimb/physiology ; Glucose Transporter Type 4 ; Insulin/pharmacology ; Male ; Monosaccharide Transport Proteins/physiology ; Muscle, Skeletal/drug effects ; Muscle, Skeletal/metabolism ; Rats ; Rats, Wistar ; Reference Values
Czasopismo naukowe
Tytuł :
Divergent effects of acute exercise and endurance training on UCP3 expression.
Autorzy :
Hesselink MK
Schrauwen P
Holloszy JO
Jones TE
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Źródło :
American journal of physiology. Endocrinology and metabolism [Am J Physiol Endocrinol Metab] 2003 Feb; Vol. 284 (2), pp. E449-50; author reply 450-1.
Typ publikacji :
Letter; Comment
MeSH Terms :
Carrier Proteins/*metabolism
Exercise/*physiology
Mitochondria/*metabolism
Muscle, Skeletal/*physiology
Physical Endurance/*physiology
Humans ; Ion Channels ; Mitochondrial Proteins ; Uncoupling Protein 3
Opinia redakcyjna
Tytuł :
Exercise induces an increase in muscle UCP3 as a component of the increase in mitochondrial biogenesis.
Autorzy :
Jones TE; Department of Medicine, Washington University School of Medicine, St. Louis, Missouri 63110, USA.
Baar K
Ojuka E
Chen M
Holloszy JO
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Źródło :
American journal of physiology. Endocrinology and metabolism [Am J Physiol Endocrinol Metab] 2003 Jan; Vol. 284 (1), pp. E96-101. Date of Electronic Publication: 2002 Sep 17.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Carrier Proteins/*metabolism
Mitochondria, Muscle/*metabolism
Muscle, Skeletal/*metabolism
Physical Exertion/*physiology
Animals ; Carrier Proteins/genetics ; Ion Channels ; Male ; Mitochondrial Proteins ; Muscle Fibers, Fast-Twitch/metabolism ; Muscle Fibers, Fast-Twitch/ultrastructure ; Muscle Fibers, Slow-Twitch/metabolism ; Muscle Fibers, Slow-Twitch/ultrastructure ; Muscle, Skeletal/ultrastructure ; Physical Conditioning, Animal ; RNA, Messenger/analysis ; Rats ; Rats, Wistar ; Swimming ; Uncoupling Protein 3
Czasopismo naukowe
Tytuł :
Intermittent increases in cytosolic Ca2+ stimulate mitochondrial biogenesis in muscle cells.
Autorzy :
Ojuka EO; Department of Medicine, Washington University School of Medicine, St. Louis, Missouri 63110, USA.
Jones TE
Han DH
Chen M
Wamhoff BR
Sturek M
Holloszy JO
Pokaż więcej
Źródło :
American journal of physiology. Endocrinology and metabolism [Am J Physiol Endocrinol Metab] 2002 Nov; Vol. 283 (5), pp. E1040-5.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Aminoimidazole Carboxamide/*analogs & derivatives
Calcium/*metabolism
Mitochondria/*metabolism
Muscle Fibers, Skeletal/*metabolism
5-Aminolevulinate Synthetase/metabolism ; Adenosine Triphosphate/metabolism ; Aminoimidazole Carboxamide/pharmacology ; Animals ; Caffeine/pharmacology ; Cells, Cultured ; Cytochrome c Group/metabolism ; Cytosol/metabolism ; Enzyme Inhibitors/pharmacology ; Gene Expression/physiology ; Hydrogen-Ion Concentration ; Hypoglycemic Agents/pharmacology ; Ionomycin/pharmacology ; Ionophores/pharmacology ; Muscle Fibers, Skeletal/cytology ; Muscle Fibers, Skeletal/drug effects ; Oleic Acid/metabolism ; Oxidation-Reduction ; Phosphodiesterase Inhibitors/pharmacology ; Rats ; Ribonucleotides/pharmacology ; Sulfonamides/pharmacology
Czasopismo naukowe
Tytuł :
Glucose transport rate and glycogen synthase activity both limit skeletal muscle glycogen accumulation.
Autorzy :
Fisher JS; Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri 63110, USA. />Nolte LA
Kawanaka K
Han DH
Jones TE
Holloszy JO
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Źródło :
American journal of physiology. Endocrinology and metabolism [Am J Physiol Endocrinol Metab] 2002 Jun; Vol. 282 (6), pp. E1214-21.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Glucose/*metabolism
Glycogen/*metabolism
Glycogen Synthase/*metabolism
Muscle, Skeletal/*metabolism
Animals ; Biological Transport ; Calcium-Calmodulin-Dependent Protein Kinases/antagonists & inhibitors ; Enzyme Inhibitors/pharmacology ; Fasting ; Glycogen Synthase Kinases ; Indoles/pharmacology ; Insulin/pharmacology ; Kinetics ; Lithium/pharmacology ; Male ; Maleimides/pharmacology ; Muscle, Skeletal/drug effects ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Regulation of GLUT4 biogenesis in muscle: evidence for involvement of AMPK and Ca(2+).
Autorzy :
Ojuka EO; Department of Medicine, Washington University School of Medicine, St. Louis, Missouri 63110, USA.
Jones TE
Nolte LA
Chen M
Wamhoff BR
Sturek M
Holloszy JO
Pokaż więcej
Źródło :
American journal of physiology. Endocrinology and metabolism [Am J Physiol Endocrinol Metab] 2002 May; Vol. 282 (5), pp. E1008-13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Muscle Proteins*
Nerve Tissue Proteins*
Aminoimidazole Carboxamide/*analogs & derivatives
Calcium/*metabolism
Monosaccharide Transport Proteins/*biosynthesis
Muscle, Skeletal/*enzymology
Protein Kinases/*metabolism
Aminoimidazole Carboxamide/pharmacology ; Animals ; Caffeine/pharmacology ; Calcium-Calmodulin-Dependent Protein Kinases/metabolism ; Cells, Cultured ; Cytosol/metabolism ; DNA-Binding Proteins/metabolism ; Glucose Transporter Type 1 ; Glucose Transporter Type 3 ; Glucose Transporter Type 4 ; Hypoglycemic Agents/pharmacology ; MEF2 Transcription Factors ; Male ; Monosaccharide Transport Proteins/metabolism ; Muscle Fibers, Skeletal/cytology ; Muscle Fibers, Skeletal/drug effects ; Muscle Fibers, Skeletal/enzymology ; Muscle, Skeletal/cytology ; Myogenic Regulatory Factors ; Phosphodiesterase Inhibitors/pharmacology ; Rats ; Rats, Wistar ; Ribonucleotides/pharmacology ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł :
Pharmacokinetic interaction between tacrolimus and diltiazem: dose-response relationship in kidney and liver transplant recipients.
Autorzy :
Jones TE; Department of Pharmacy, The Queen Elizabeth Hospital, Woodville South, South Australia, Australia. />Morris RG
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Źródło :
Clinical pharmacokinetics [Clin Pharmacokinet] 2002; Vol. 41 (5), pp. 381-8.
Typ publikacji :
Journal Article
MeSH Terms :
Kidney Transplantation*/statistics & numerical data
Liver Transplantation*/statistics & numerical data
Calcium Channel Blockers/*pharmacokinetics
Diltiazem/*pharmacokinetics
Immunosuppressive Agents/*pharmacokinetics
Tacrolimus/*pharmacokinetics
Area Under Curve ; Calcium Channel Blockers/blood ; Calcium Channel Blockers/therapeutic use ; Diltiazem/blood ; Diltiazem/therapeutic use ; Dose-Response Relationship, Drug ; Drug Interactions ; Female ; Graft Rejection/blood ; Graft Rejection/drug therapy ; Humans ; Immunosuppressive Agents/blood ; Immunosuppressive Agents/therapeutic use ; Male ; Middle Aged ; Tacrolimus/blood ; Tacrolimus/therapeutic use
Czasopismo naukowe

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