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    Wyświetlanie 1-6 z 6
    Tytuł:
    Interindividual variation in human cortical cell type abundance and expression.
    Autorzy:
    Johansen N; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Somasundaram S; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Travaglini KJ; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Yanny AM; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Shumyatcher M; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Casper T; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Cobbs C; Swedish Neuroscience Institute, Seattle,WA 98122, USA.
    Dee N; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Ellenbogen R; Department of Neurological Surgery, University of Washington, Seattle, WA 98104, USA.
    Ferreira M; Department of Neurological Surgery, University of Washington, Seattle, WA 98104, USA.
    Goldy J; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Guzman J; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Gwinn R; Swedish Neuroscience Institute, Seattle,WA 98122, USA.
    Hirschstein D; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Jorstad NL; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Keene CD; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA 98104, USA.
    Ko A; Department of Neurological Surgery, University of Washington, Seattle, WA 98104, USA.
    Levi BP; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Ojemann JG; Department of Neurological Surgery, University of Washington, Seattle, WA 98104, USA.
    Pham T; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Shapovalova N; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Silbergeld D; Department of Neurological Surgery, University of Washington, Seattle, WA 98104, USA.
    Sulc J; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Torkelson A; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Tung H; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Smith K; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Lein ES; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Bakken TE; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Hodge RD; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Miller JA; Allen Institute for Brain Science, Seattle, WA 98109, USA.
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    Źródło:
    Science (New York, N.Y.) [Science] 2023 Oct 13; Vol. 382 (6667), pp. eadf2359. Date of Electronic Publication: 2023 Oct 13.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Temporal Lobe*/cytology
    Temporal Lobe*/metabolism
    Transcriptome*
    Adult ; Humans ; Epilepsy/metabolism ; Gene Expression Profiling ; Neurons/metabolism ; Nervous System Diseases/genetics ; Mental Disorders/genetics
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Transcriptomic cytoarchitecture reveals principles of human neocortex organization.
    Autorzy:
    Jorstad NL; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Close J; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Johansen N; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Yanny AM; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Barkan ER; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Travaglini KJ; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Bertagnolli D; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Campos J; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Casper T; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Crichton K; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Dee N; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Ding SL; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Gelfand E; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Goldy J; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Hirschstein D; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Kiick K; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Kroll M; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Kunst M; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Lathia K; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Long B; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Martin N; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    McMillen D; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Pham T; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Rimorin C; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Ruiz A; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Shapovalova N; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Shehata S; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Siletti K; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 171 77 Stockholm, Sweden.
    Somasundaram S; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Sulc J; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Tieu M; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Torkelson A; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Tung H; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Callaway EM; Systems Neurobiology Laboratories, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA.
    Hof PR; Nash Family Department of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
    Keene CD; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA 98195, USA.
    Levi BP; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Linnarsson S; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 171 77 Stockholm, Sweden.
    Mitra PP; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, NY 11724, USA.
    Smith K; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Hodge RD; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Bakken TE; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Lein ES; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Pokaż więcej
    Źródło:
    Science (New York, N.Y.) [Science] 2023 Oct 13; Vol. 382 (6667), pp. eadf6812. Date of Electronic Publication: 2023 Oct 13.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Neocortex*/metabolism
    Neocortex*/ultrastructure
    Humans ; Neurons/classification ; Neurons/metabolism ; Transcriptome ; Single-Cell Gene Expression Analysis ; Phylogeny
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Comparative transcriptomics reveals human-specific cortical features.
    Autorzy:
    Jorstad NL; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Song JHT; Allen Discovery Center for Human Brain Evolution, Boston Children's Hospital and Harvard Medical School, Boston, MA 02115, USA.; Division of Genetics and Genomics, Boston Children's Hospital, Boston, MA 02115, USA.; Department of Pediatrics and Neurology, Harvard Medical School, Boston, MA 02115, USA.; Howard Hughes Medical Institute, Boston Children's Hospital, Boston, MA 02115, USA.
    Exposito-Alonso D; Allen Discovery Center for Human Brain Evolution, Boston Children's Hospital and Harvard Medical School, Boston, MA 02115, USA.; Division of Genetics and Genomics, Boston Children's Hospital, Boston, MA 02115, USA.; Department of Pediatrics and Neurology, Harvard Medical School, Boston, MA 02115, USA.; Howard Hughes Medical Institute, Boston Children's Hospital, Boston, MA 02115, USA.
    Suresh H; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.
    Castro-Pacheco N; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.
    Krienen FM; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.
    Yanny AM; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Close J; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Gelfand E; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Long B; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Seeman SC; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Travaglini KJ; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Basu S; LKEB, Department of Radiology, Leiden University Medical Center, Leiden, Netherlands.; Computer Graphics and Visualization Group, Delft University of Technology, Delft, Netherlands.
    Beaudin M; Allen Discovery Center for Human Brain Evolution, Boston Children's Hospital and Harvard Medical School, Boston, MA 02115, USA.; Division of Genetics and Genomics, Boston Children's Hospital, Boston, MA 02115, USA.; Department of Pediatrics and Neurology, Harvard Medical School, Boston, MA 02115, USA.; Howard Hughes Medical Institute, Boston Children's Hospital, Boston, MA 02115, USA.
    Bertagnolli D; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Crow M; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.; Stanley Institute for Cognitive Genomics, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.
    Ding SL; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Eggermont J; LKEB, Department of Radiology, Leiden University Medical Center, Leiden, Netherlands.
    Glandon A; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Goldy J; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Kiick K; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Kroes T; LKEB, Department of Radiology, Leiden University Medical Center, Leiden, Netherlands.
    McMillen D; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Pham T; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Rimorin C; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Siletti K; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.
    Somasundaram S; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Tieu M; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Torkelson A; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Feng G; McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
    Hopkins WD; Keeling Center for Comparative Medicine and Research, University of Texas, MD Anderson Cancer Center, Houston, TX 78602, USA.
    Höllt T; Computer Graphics and Visualization Group, Delft University of Technology, Delft, Netherlands.
    Keene CD; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA 98195, USA.
    Linnarsson S; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.
    McCarroll SA; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
    Lelieveldt BP; LKEB, Department of Radiology, Leiden University Medical Center, Leiden, Netherlands.; Pattern Recognition and Bioinformatics Group, Delft University of Technology, Delft, Netherlands.
    Sherwood CC; Department of Anthropology, The George Washington University, Washington, DC 20037, USA.
    Smith K; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Walsh CA; Allen Discovery Center for Human Brain Evolution, Boston Children's Hospital and Harvard Medical School, Boston, MA 02115, USA.; Division of Genetics and Genomics, Boston Children's Hospital, Boston, MA 02115, USA.; Department of Pediatrics and Neurology, Harvard Medical School, Boston, MA 02115, USA.; Howard Hughes Medical Institute, Boston Children's Hospital, Boston, MA 02115, USA.
    Dobin A; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.
    Gillis J; Department of Physiology, University of Toronto, Toronto, ON, Canada.
    Lein ES; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Hodge RD; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Bakken TE; Allen Institute for Brain Science, Seattle, WA 98109, USA.
    Pokaż więcej
    Źródło:
    Science (New York, N.Y.) [Science] 2023 Oct 13; Vol. 382 (6667), pp. eade9516. Date of Electronic Publication: 2023 Oct 13.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Hominidae*/genetics
    Hominidae*/physiology
    Neocortex*/physiology
    Temporal Lobe*/physiology
    Cognition*
    Animals ; Humans ; Gene Expression Profiling ; Gorilla gorilla/genetics ; Macaca mulatta/genetics ; Pan troglodytes/genetics ; Phylogeny ; Transcriptome ; Species Specificity
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Wild-type microglia do not reverse pathology in mouse models of Rett syndrome.
    Autorzy:
    Wang J; Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
    Wegener JE; Department of Pediatrics and Adolescent Medicine, Division of Pediatric Neurology, University Medical Center Göttingen, Robert-Koch-Strasse 40, 37075 Göttingen, Germany.
    Huang TW; 1] Jan and Dan Duncan Neurological Research Institute (Texas Children's Hospital), Baylor College of Medicine, Houston, Texas 77030, USA [2] Program in Developmental Biology, Baylor College of Medicine, Houston, Texas 77030, USA.
    Sripathy S; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.
    De Jesus-Cortes H; 1] Graduate Program of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA [2] Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242, USA.
    Xu P; Graduate Program of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
    Tran S; Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
    Knobbe W; Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
    Leko V; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.
    Britt J; Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242, USA.
    Starwalt R; Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
    McDaniel L; Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242, USA.
    Ward CS; Jan and Dan Duncan Neurological Research Institute (Texas Children's Hospital), Baylor College of Medicine, Houston, Texas 77030, USA.
    Parra D; Jan and Dan Duncan Neurological Research Institute (Texas Children's Hospital), Baylor College of Medicine, Houston, Texas 77030, USA.
    Newcomb B; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.
    Lao U; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.
    Nourigat C; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.
    Flowers DA; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.
    Cullen S; Program in Developmental Biology, Baylor College of Medicine, Houston, Texas 77030, USA.
    Jorstad NL; Department of Pathology, University of Washington School of Medicine, Seattle, Washington 98195, USA.
    Yang Y; Department of Pathology, University of Washington School of Medicine, Seattle, Washington 98195, USA.
    Glaskova L; Department of Pathology, University of Washington School of Medicine, Seattle, Washington 98195, USA.
    Vingeau S
    Kozlitina J; Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
    Yetman MJ; Department of Neuroscience, Baylor College of Medicine, Houston, Texas 77030, USA.
    Jankowsky JL; Department of Neuroscience, Baylor College of Medicine, Houston, Texas 77030, USA.
    Reichardt SD; Institute for Cellular and Molecular Immunology; University of Göttingen Medical School, Humboldtallee 34, 37073 Göttingen, Germany.
    Reichardt HM; Institute for Cellular and Molecular Immunology; University of Göttingen Medical School, Humboldtallee 34, 37073 Göttingen, Germany.
    Gärtner J; Department of Pediatrics and Adolescent Medicine, Division of Pediatric Neurology, University Medical Center Göttingen, Robert-Koch-Strasse 40, 37075 Göttingen, Germany.
    Bartolomei MS; Department of Cell &Developmental Biology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
    Fang M; 1] Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA [2] Department of Pathology, University of Washington School of Medicine, Seattle, Washington 98195, USA.
    Loeb K; 1] Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA [2] Department of Pathology, University of Washington School of Medicine, Seattle, Washington 98195, USA.
    Keene CD; Department of Pathology, University of Washington School of Medicine, Seattle, Washington 98195, USA.
    Bernstein I; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.
    Goodell M; 1] Program in Developmental Biology, Baylor College of Medicine, Houston, Texas 77030, USA [2] Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030, USA [3] Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, Texas 77030, USA [4] Stem Cell and Regenerative Medicine Center, Baylor College of Medicine, Houston, Texas 77030, USA [5] Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA [6] Program in Translational Biology and Molecular Medicine, Baylor College of Medicine, Houston, Texas 77030, USA.
    Brat DJ; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia 30322, USA.
    Huppke P; Department of Pediatrics and Adolescent Medicine, Division of Pediatric Neurology, University Medical Center Göttingen, Robert-Koch-Strasse 40, 37075 Göttingen, Germany.
    Neul JL; 1] Jan and Dan Duncan Neurological Research Institute (Texas Children's Hospital), Baylor College of Medicine, Houston, Texas 77030, USA [2] Program in Developmental Biology, Baylor College of Medicine, Houston, Texas 77030, USA [3] Department of Neuroscience, Baylor College of Medicine, Houston, Texas 77030, USA [4] Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030, USA [5] Stem Cell and Regenerative Medicine Center, Baylor College of Medicine, Houston, Texas 77030, USA [6] Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA.
    Bedalov A; 1] Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA [2] Department of Medicine, University of Washington School of Medicine, Seattle, Washington 98105, USA.
    Pieper AA; 1] Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242, USA [2] Department of Neurology, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242, USA [3] Veterans Affairs, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242, USA [4] Weill Cornell Autism Research Program, Weill Cornell Medical College, New York, New York 10065, USA.
    Pokaż więcej
    Źródło:
    Nature [Nature] 2015 May 21; Vol. 521 (7552), pp. E1-4.
    Typ publikacji:
    Letter
    MeSH Terms:
    Disease Progression*
    Methyl-CpG-Binding Protein 2/*metabolism
    Microglia/*cytology
    Microglia/*physiology
    Rett Syndrome/*pathology
    Animals ; Female ; Male
    Opinia redakcyjna
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Suppressed retinal degeneration in aged wild type and APPswe/PS1ΔE9 mice by bone marrow transplantation.
    Autorzy:
    Yang Y; Department of Pathology, University of Washington, Seattle, Washington, USA.
    Shiao C
    Hemingway JF
    Jorstad NL
    Shalloway BR
    Chang R
    Keene CD
    Pokaż więcej
    Źródło:
    PloS one [PLoS One] 2013 Jun 04; Vol. 8 (6), pp. e64246. Date of Electronic Publication: 2013 Jun 04 (Print Publication: 2013).
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Aging*
    Bone Marrow Transplantation*
    Retinal Degeneration/*surgery
    Amyloid beta-Peptides/metabolism ; Animals ; Female ; Histocompatibility Antigens Class II/metabolism ; Immunity, Innate ; Male ; Mice ; Mice, Transgenic ; Microglia/metabolism ; Microglia/pathology ; Oxidative Stress ; Retinal Degeneration/immunology ; Retinal Degeneration/metabolism ; Retinal Degeneration/pathology ; Retinal Ganglion Cells/metabolism ; Retinal Ganglion Cells/pathology ; tau Proteins/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
      Wyświetlanie 1-6 z 6

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