JN: "Journal of biomedical science [J Biomed Sci] NLMUID: 9421567" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Proteasome inhibitors restore the STAT1 pathway and enhance the expression of MHC class I on human colon cancer cells.
Autorzy:: Liang YH; Graduate Institutes of Oncology, National Taiwan University College of Medicine, No 7, Chung-Shan South Rd, Taipei, 10002, Taiwan, R.O.C.; Graduate Institutes of Centers of Genomic and Precision Medicine, National Taiwan University College of Medicine, Taipei, Taiwan, R.O.C.; Departments of Oncology, National Taiwan University Hospital, Taipei, Taiwan, R.O.C.; National Taiwan University Cancer Center, Taipei, Taiwan, R.O.C.
Chen KH; Graduate Institutes of Oncology, National Taiwan University College of Medicine, No 7, Chung-Shan South Rd, Taipei, 10002, Taiwan, R.O.C.; Departments of Oncology, National Taiwan University Hospital, Taipei, Taiwan, R.O.C.; National Taiwan University Cancer Center, Taipei, Taiwan, R.O.C.
Tsai JH; Departments of Pathology, National Taiwan University Hospital, Taipei, Taiwan, R.O.C.
Cheng YM; Departments of Pathology, National Taiwan University Hospital, Taipei, Taiwan, R.O.C.
Lee CC; Graduate Institutes of Oncology, National Taiwan University College of Medicine, No 7, Chung-Shan South Rd, Taipei, 10002, Taiwan, R.O.C.; Graduate Institutes of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan, R.O.C.
Kao CH; Graduate Institutes of Oncology, National Taiwan University College of Medicine, No 7, Chung-Shan South Rd, Taipei, 10002, Taiwan, R.O.C.; Graduate Institutes of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan, R.O.C.
Chan KY; Graduate Institutes of Oncology, National Taiwan University College of Medicine, No 7, Chung-Shan South Rd, Taipei, 10002, Taiwan, R.O.C.
Chen YT; Graduate Institutes of Centers of Genomic and Precision Medicine, National Taiwan University College of Medicine, Taipei, Taiwan, R.O.C.
Hsu WL; Graduate Institutes of Centers of Genomic and Precision Medicine, National Taiwan University College of Medicine, Taipei, Taiwan, R.O.C.
Yeh KH; Graduate Institutes of Oncology, National Taiwan University College of Medicine, No 7, Chung-Shan South Rd, Taipei, 10002, Taiwan, R.O.C.. .; Graduate Institutes of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan, R.O.C.. .; Departments of Oncology, National Taiwan University Hospital, Taipei, Taiwan, R.O.C.. .; National Taiwan University Cancer Center, Taipei, Taiwan, R.O.C.. .; Pokaż więcej
Źródło:: Journal of biomedical science [J Biomed Sci] 2021 Nov 10; Vol. 28 (1), pp. 75. Date of Electronic Publication: 2021 Nov 10.
Typ publikacji:: Journal Article
MeSH Terms:: Colonic Neoplasms/*physiopathology
Gene Expression/*drug effects
Genes, MHC Class I/*drug effects
Histocompatibility Antigens Class I/*genetics
Proteasome Inhibitors/*pharmacology
STAT1 Transcription Factor/*genetics
Signal Transduction/*drug effects
Cell Line, Tumor ; Humans ; STAT1 Transcription Factor/metabolism

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Skocz do pozycji: 2.

Tytuł:: Modular self-assembly system for development of oligomeric, highly internalizing and potent cytotoxic conjugates targeting fibroblast growth factor receptors.
Autorzy:: Poźniak M; Faculty of Biotechnology, Department of Protein Engineering, University of Wroclaw, Joliot-Curie 14a, 50-383, Wroclaw, Poland.
Porębska N; Faculty of Biotechnology, Department of Protein Engineering, University of Wroclaw, Joliot-Curie 14a, 50-383, Wroclaw, Poland.
Jastrzębski K; Laboratory of Cell Biology, International Institute of Molecular and Cell Biology, 02-109, Warsaw, Poland.
Krzyścik MA; Faculty of Biotechnology, Department of Protein Engineering, University of Wroclaw, Joliot-Curie 14a, 50-383, Wroclaw, Poland.
Kucińska M; Faculty of Biotechnology, Department of Protein Engineering, University of Wroclaw, Joliot-Curie 14a, 50-383, Wroclaw, Poland.
Zarzycka W; Faculty of Biotechnology, Department of Protein Engineering, University of Wroclaw, Joliot-Curie 14a, 50-383, Wroclaw, Poland.
Barbach A; Faculty of Biotechnology, Department of Protein Engineering, University of Wroclaw, Joliot-Curie 14a, 50-383, Wroclaw, Poland.
Zakrzewska M; Faculty of Biotechnology, Department of Protein Engineering, University of Wroclaw, Joliot-Curie 14a, 50-383, Wroclaw, Poland.
Otlewski J; Faculty of Biotechnology, Department of Protein Engineering, University of Wroclaw, Joliot-Curie 14a, 50-383, Wroclaw, Poland.
Miączyńska M; Laboratory of Cell Biology, International Institute of Molecular and Cell Biology, 02-109, Warsaw, Poland.
Opaliński Ł; Faculty of Biotechnology, Department of Protein Engineering, University of Wroclaw, Joliot-Curie 14a, 50-383, Wroclaw, Poland. .; Pokaż więcej
Źródło:: Journal of biomedical science [J Biomed Sci] 2021 Oct 11; Vol. 28 (1), pp. 69. Date of Electronic Publication: 2021 Oct 11.
Typ publikacji:: Journal Article
MeSH Terms:: Signal Transduction*
Receptor, Fibroblast Growth Factor, Type 1/*genetics
Cell Line, Tumor ; Humans ; Protein Binding ; Receptor, Fibroblast Growth Factor, Type 1/metabolism

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Skocz do pozycji: 3.

Tytuł:: MicroRNA-138-1-3p sensitizes sorafenib to hepatocellular carcinoma by targeting PAK5 mediated β-catenin/ABCB1 signaling pathway.
Autorzy:: Li TT; Department of Pathology, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, Jiangsu, 221004, People's Republic of China.; Department of Pathology and Pathophysiology, Jiangsu Vocational College of Medicine, Yancheng, 224005, Jiangsu, China.
Mou J; Jiangsu Key Laboratory of New Drug and Clinical Pharmacy, School of Pharmacy, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, 221006, China.
Pan YJ; Department of Pathology, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, Jiangsu, 221004, People's Republic of China.
Huo FC; Department of Pathology, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, Jiangsu, 221004, People's Republic of China.
Du WQ; Department of Pathology, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, Jiangsu, 221004, People's Republic of China.
Liang J; Department of Pathology, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, Jiangsu, 221004, People's Republic of China.
Wang Y; Department of Pathology, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, Jiangsu, 221004, People's Republic of China.
Zhang LS; Department of Oncological Radiotherapy, The Second Affiliated Hospital of Xuzhou Medical University, Xuzhou, China. .
Pei DS; Department of Pathology, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, Jiangsu, 221004, People's Republic of China. .; Pokaż więcej
Źródło:: Journal of biomedical science [J Biomed Sci] 2021 Aug 02; Vol. 28 (1), pp. 56. Date of Electronic Publication: 2021 Aug 02.
Typ publikacji:: Journal Article
MeSH Terms:: Drug Resistance, Neoplasm*
Carcinoma, Hepatocellular/*drug therapy
Liver Neoplasms/*drug therapy
MicroRNAs/*metabolism
Protein Kinase Inhibitors/*pharmacology
Signal Transduction/*drug effects
Sorafenib/*pharmacology
Animals ; Antineoplastic Agents/pharmacology ; Female ; Gene Expression Regulation, Neoplastic ; Mice ; Mice, Inbred BALB C ; Mice, Nude

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Skocz do pozycji: 4.

Tytuł:: Inflammatory signaling mechanisms in bipolar disorder.
Autorzy:: Jones GH; Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center at Houston (UTHealth), 1941 East Road, Houston, TX, 77054, USA. .
Vecera CM; Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center at Houston (UTHealth), 1941 East Road, Houston, TX, 77054, USA.
Pinjari OF; Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center at Houston (UTHealth), 1941 East Road, Houston, TX, 77054, USA.
Machado-Vieira R; Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center at Houston (UTHealth), 1941 East Road, Houston, TX, 77054, USA.; Pokaż więcej
Źródło:: Journal of biomedical science [J Biomed Sci] 2021 Jun 11; Vol. 28 (1), pp. 45. Date of Electronic Publication: 2021 Jun 11.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Bipolar Disorder/*physiopathology
Inflammation/*physiopathology
Signal Transduction/*immunology
Animals ; Bipolar Disorder/immunology ; Humans ; Mice

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Skocz do pozycji: 5.

Tytuł:: Notch-ing up knowledge on molecular mechanisms of skin fibrosis: focus on the multifaceted Notch signalling pathway.
Autorzy:: Condorelli AG; Genodermatosis Unit, Genetics and Rare Diseases Research Division, Bambino Gesù Children's Hospital, IRCCS, Piazza Sant' Onofrio 4, 00165, Rome, Italy. .
El Hachem M; Dermatology Unit and Genodermatosis Unit, Genetics and Rare Diseases Research Division, Bambino Gesù Children's Hospital, IRCCS, Piazza Sant' Onofrio 4, 00165, Rome, Italy.
Zambruno G; Genodermatosis Unit, Genetics and Rare Diseases Research Division, Bambino Gesù Children's Hospital, IRCCS, Piazza Sant' Onofrio 4, 00165, Rome, Italy.
Nystrom A; Department of Dermatology, Medical Faculty, Medical Center, University of Freiburg, Freiburg, Germany.
Candi E; Department of Experimental Medicine, University of Rome 'Tor Vergata', via Montpellier, 1, 00133, Rome, Italy.; IDI-IRCCS, via Monti di Creta 104, 00167, Rome, Italy.
Castiglia D; Laboratory of Molecular and Cell Biology, IDI-IRCCS, via Monti di Creta 104, 00167, Rome, Italy.; Pokaż więcej
Źródło:: Journal of biomedical science [J Biomed Sci] 2021 May 09; Vol. 28 (1), pp. 36. Date of Electronic Publication: 2021 May 09.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Signal Transduction*
Cicatrix, Hypertrophic/*genetics
Fibrosis/*genetics
Receptors, Notch/*metabolism
Scleroderma, Systemic/*genetics
Cicatrix, Hypertrophic/pathology ; Fibrosis/pathology ; Scleroderma, Systemic/pathology ; Skin/pathology

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Skocz do pozycji: 6.

Tytuł:: RhoA: a dubious molecule in cardiac pathophysiology.
Autorzy:: Kilian LS; Department of Internal Medicine III (Cardiology, Angiology, Intensive Care), University Medical Center Kiel, Rosalind-Franklin Str. 12, 24105, Kiel, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Hamburg/Kiel/Lübeck, 24105, Kiel, Germany.
Voran J; Department of Internal Medicine III (Cardiology, Angiology, Intensive Care), University Medical Center Kiel, Rosalind-Franklin Str. 12, 24105, Kiel, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Hamburg/Kiel/Lübeck, 24105, Kiel, Germany.
Frank D; Department of Internal Medicine III (Cardiology, Angiology, Intensive Care), University Medical Center Kiel, Rosalind-Franklin Str. 12, 24105, Kiel, Germany. .; DZHK (German Centre for Cardiovascular Research), partner site Hamburg/Kiel/Lübeck, 24105, Kiel, Germany. .
Rangrez AY; Department of Internal Medicine III (Cardiology, Angiology, Intensive Care), University Medical Center Kiel, Rosalind-Franklin Str. 12, 24105, Kiel, Germany. .; DZHK (German Centre for Cardiovascular Research), partner site Hamburg/Kiel/Lübeck, 24105, Kiel, Germany. .; Department of Cardiology, Angiology and Pneumology, University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany. .; Pokaż więcej
Źródło:: Journal of biomedical science [J Biomed Sci] 2021 Apr 28; Vol. 28 (1), pp. 33. Date of Electronic Publication: 2021 Apr 28.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Heart Diseases/*physiopathology
Signal Transduction/*physiology
rhoA GTP-Binding Protein/*genetics
Animals ; Heart Diseases/genetics ; Humans ; Rats ; rhoA GTP-Binding Protein/metabolism

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Skocz do pozycji: 7.

Tytuł:: NKX6-1 mediates cancer stem-like properties and regulates sonic hedgehog signaling in leiomyosarcoma.
Autorzy:: Su PH; Translational Epigenetics Center, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan.; Department of Obstetrics and Gynecology, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan.; Department of Obstetrics and Gynecology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
Huang RL; Translational Epigenetics Center, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan.; Department of Obstetrics and Gynecology, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan.; Department of Obstetrics and Gynecology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
Lai HC; Translational Epigenetics Center, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan.; Department of Obstetrics and Gynecology, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan.; Department of Obstetrics and Gynecology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.; Department of Obstetrics and Gynecology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Chen LY; Translational Epigenetics Center, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan.; Department of Obstetrics and Gynecology, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan.
Weng YC; Translational Epigenetics Center, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan.; Department of Obstetrics and Gynecology, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan.
Wang CC; Department of Orthopaedics, Tri-Service General Hospital, National Defense Medical Center, Neihu District, No. 325, Sec. 2, Chengong Road, Taipei, 11490, Taiwan.
Wu CC; Department of Orthopaedics, Tri-Service General Hospital, National Defense Medical Center, Neihu District, No. 325, Sec. 2, Chengong Road, Taipei, 11490, Taiwan. .; Pokaż więcej
Źródło:: Journal of biomedical science [J Biomed Sci] 2021 Apr 27; Vol. 28 (1), pp. 32. Date of Electronic Publication: 2021 Apr 27.
Typ publikacji:: Journal Article
MeSH Terms:: Signal Transduction*
Hedgehog Proteins/*genetics
Homeodomain Proteins/*genetics
Leiomyosarcoma/*metabolism
Neoplastic Stem Cells/*metabolism
Animals ; Cell Line, Tumor ; Cell Proliferation ; Cell Survival ; Hedgehog Proteins/metabolism ; Homeodomain Proteins/metabolism ; Mice ; Mice, Nude

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Skocz do pozycji: 8.

Tytuł:: Role of thyroid hormone-integrin αvβ3-signal and therapeutic strategies in colorectal cancers.
Autorzy:: Yang YSH; Joint Biobank, Office of Human Research, Taipei Medical University, Taipei, 11031, Taiwan.
Ko PJ; School of Medicine, I-Shou University, Kaohsiung, 84001, Taiwan.; Department of Pediatrics, E-DA Hospital, Kaohsiung, 82445, Taiwan.
Pan YS; Graduate Institute of Nanomedicine and Medical Engineering, College of Medical Engineering, Taipei Medical University, Taipei, 11031, Taiwan.
Lin HY; Graduate Institute for Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei, 11031, Taiwan. .; Cancer Center, Wan Fang Hospital, Taipei Medical University, Taipei, 11031, Taiwan. .; Traditional Herbal Medicine Research Center of Taipei Medical University Hospital, Taipei Medical University, Taipei, 11031, Taiwan. .; TMU Research Center of Cancer Translational Medicine, Taipei Medical University, Taipei, 11031, Taiwan. .; Pharmaceutical Research Institute, Albany College of Pharmacy and Health Sciences, Albany, NY, 12144, USA. .
Whang-Peng J; Graduate Institute for Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei, 11031, Taiwan.; Cancer Center, Wan Fang Hospital, Taipei Medical University, Taipei, 11031, Taiwan.
Davis PJ; Pharmaceutical Research Institute, Albany College of Pharmacy and Health Sciences, Albany, NY, 12144, USA.; Albany Medical College, Albany, NY, 12144, USA.
Wang K; Graduate Institute of Nanomedicine and Medical Engineering, College of Medical Engineering, Taipei Medical University, Taipei, 11031, Taiwan.; Pokaż więcej
Źródło:: Journal of biomedical science [J Biomed Sci] 2021 Apr 08; Vol. 28 (1), pp. 24. Date of Electronic Publication: 2021 Apr 08.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Signal Transduction*
Antineoplastic Agents/*therapeutic use
Colorectal Neoplasms/*prevention & control
Integrin alphaVbeta3/*therapeutic use
Thyroxine/*therapeutic use
Genes, erbB-1 ; Genes, ras ; Humans

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Skocz do pozycji: 9.

Tytuł:: CircNOL10 suppresses breast cancer progression by sponging miR-767-5p to regulate SOCS2/JAK/STAT signaling.
Autorzy:: Wang F; Department of Breast Surgery, The First Affiliated Hospital of Zhengzhou University, No.1 Jianshe East Road, Erqi, Zhengzhou, 450000, China.
Wang X; Department of Breast Surgery, Affiliated Hospital of Hebei University, Baoding, 071000, China.
Li J; Department of Breast Surgery, The First Affiliated Hospital of Zhengzhou University, No.1 Jianshe East Road, Erqi, Zhengzhou, 450000, China.
Lv P; Department of Breast Surgery, The First Affiliated Hospital of Zhengzhou University, No.1 Jianshe East Road, Erqi, Zhengzhou, 450000, China.
Han M; Department of Breast Surgery, The First Affiliated Hospital of Zhengzhou University, No.1 Jianshe East Road, Erqi, Zhengzhou, 450000, China.
Li L; Department of Breast Surgery, The First Affiliated Hospital of Zhengzhou University, No.1 Jianshe East Road, Erqi, Zhengzhou, 450000, China.
Chen Z; Department of Breast Surgery, The First Affiliated Hospital of Zhengzhou University, No.1 Jianshe East Road, Erqi, Zhengzhou, 450000, China.
Dong L; Department of Breast Surgery, The First Affiliated Hospital of Zhengzhou University, No.1 Jianshe East Road, Erqi, Zhengzhou, 450000, China.
Wang N; Department of Breast Surgery, The First Affiliated Hospital of Zhengzhou University, No.1 Jianshe East Road, Erqi, Zhengzhou, 450000, China.
Gu Y; Department of Breast Surgery, The First Affiliated Hospital of Zhengzhou University, No.1 Jianshe East Road, Erqi, Zhengzhou, 450000, China. .; Pokaż więcej
Źródło:: Journal of biomedical science [J Biomed Sci] 2021 Jan 04; Vol. 28 (1), pp. 4. Date of Electronic Publication: 2021 Jan 04.
Typ publikacji:: Journal Article
MeSH Terms:: Disease Progression*
Signal Transduction*/drug effects
Antineoplastic Agents/*pharmacology
Breast Neoplasms/*diet therapy
MicroRNAs/*metabolism
RNA, Circular/*pharmacology
Cell Line, Tumor ; Female ; Humans

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Skocz do pozycji: 10.

Tytuł:: Amino acid-dependent control of mTORC1 signaling: a variety of regulatory modes.
Autorzy:: Takahara T; Department of Applied Biosciences, Graduate School of Bioagricultural Sciences, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, Aichi, 464-8601, Japan. .
Amemiya Y; Department of Applied Biosciences, Graduate School of Bioagricultural Sciences, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, Aichi, 464-8601, Japan.
Sugiyama R; Department of Applied Biosciences, Graduate School of Bioagricultural Sciences, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, Aichi, 464-8601, Japan.
Maki M; Department of Applied Biosciences, Graduate School of Bioagricultural Sciences, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, Aichi, 464-8601, Japan.
Shibata H; Department of Applied Biosciences, Graduate School of Bioagricultural Sciences, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, Aichi, 464-8601, Japan.; Pokaż więcej
Źródło:: Journal of biomedical science [J Biomed Sci] 2020 Aug 17; Vol. 27 (1), pp. 87. Date of Electronic Publication: 2020 Aug 17.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Gene Expression Regulation*
Signal Transduction*
Amino Acids/*metabolism
Mechanistic Target of Rapamycin Complex 1/*genetics
Animals ; Humans ; Mechanistic Target of Rapamycin Complex 1/metabolism ; Mice

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Skocz do pozycji: 11.

Tytuł:: N6-methyladenosine methyltransferase METTL3 affects the phenotype of cerebral arteriovenous malformation via modulating Notch signaling pathway.
Autorzy:: Wang LJ; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, No.119 South 4th Ring West Road, Fengtai District, Beijing, 100070, China.; China National Clinical Research Center for Neurological Diseases, Beijing, China.; Savaid Medical School, University of Chinese Academy of Sciences, Beijing, 100049, China.
Xue Y; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, No.119 South 4th Ring West Road, Fengtai District, Beijing, 100070, China.; China National Clinical Research Center for Neurological Diseases, Beijing, China.; Savaid Medical School, University of Chinese Academy of Sciences, Beijing, 100049, China.
Huo R; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, No.119 South 4th Ring West Road, Fengtai District, Beijing, 100070, China.; China National Clinical Research Center for Neurological Diseases, Beijing, China.; Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China.; Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China.
Yan Z; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, No.119 South 4th Ring West Road, Fengtai District, Beijing, 100070, China.; China National Clinical Research Center for Neurological Diseases, Beijing, China.; Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China.; Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China.
Xu H; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, No.119 South 4th Ring West Road, Fengtai District, Beijing, 100070, China.; China National Clinical Research Center for Neurological Diseases, Beijing, China.; Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China.; Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China.
Li H; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, No.119 South 4th Ring West Road, Fengtai District, Beijing, 100070, China.; China National Clinical Research Center for Neurological Diseases, Beijing, China.; Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China.; Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China.
Wang J; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, No.119 South 4th Ring West Road, Fengtai District, Beijing, 100070, China.; China National Clinical Research Center for Neurological Diseases, Beijing, China.; Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China.; Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China.
Zhang Q; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, No.119 South 4th Ring West Road, Fengtai District, Beijing, 100070, China.; China National Clinical Research Center for Neurological Diseases, Beijing, China.; Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China.; Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China.
Cao Y; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, No.119 South 4th Ring West Road, Fengtai District, Beijing, 100070, China. .; China National Clinical Research Center for Neurological Diseases, Beijing, China. .; Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China. .; Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China. .
Zhao JZ; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, No.119 South 4th Ring West Road, Fengtai District, Beijing, 100070, China. .; China National Clinical Research Center for Neurological Diseases, Beijing, China. .; Savaid Medical School, University of Chinese Academy of Sciences, Beijing, 100049, China. .; Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China. .; Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China. .; Pokaż więcej
Źródło:: Journal of biomedical science [J Biomed Sci] 2020 May 09; Vol. 27 (1), pp. 62. Date of Electronic Publication: 2020 May 09.
Typ publikacji:: Journal Article
MeSH Terms:: Phenotype*
Signal Transduction*
Intracranial Arteriovenous Malformations/*genetics
Methyltransferases/*genetics
Adolescent ; Adult ; Child ; Female ; Humans ; Intracranial Arteriovenous Malformations/pathology ; Male ; Methyltransferases/metabolism ; Middle Aged ; Receptors, Notch/physiology ; Young Adult

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Skocz do pozycji: 12.

Tytuł:: Activation of TGR5 protects blood brain barrier via the BRCA1/Sirt1 pathway after middle cerebral artery occlusion in rats.
Autorzy:: Liang H; Department of Neurology, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, 310003, China.; Department of Physiology and Pharmacology and Department of Anesthesiology, Loma Linda University, 11041 Campus St, Risley Hall, Room 219, Loma Linda, CA, 92354, USA.
Matei N; Department of Physiology and Pharmacology and Department of Anesthesiology, Loma Linda University, 11041 Campus St, Risley Hall, Room 219, Loma Linda, CA, 92354, USA.
McBride DW; The Vivian L. Smith Department of Neurosurgery, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas, 77030, USA.
Xu Y; Department of Physiology and Pharmacology and Department of Anesthesiology, Loma Linda University, 11041 Campus St, Risley Hall, Room 219, Loma Linda, CA, 92354, USA.
Tang J; Department of Physiology and Pharmacology and Department of Anesthesiology, Loma Linda University, 11041 Campus St, Risley Hall, Room 219, Loma Linda, CA, 92354, USA.
Luo B; Department of Neurology, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, 310003, China. .
Zhang JH; Department of Physiology and Pharmacology and Department of Anesthesiology, Loma Linda University, 11041 Campus St, Risley Hall, Room 219, Loma Linda, CA, 92354, USA. .; Pokaż więcej
Źródło:: Journal of biomedical science [J Biomed Sci] 2020 May 08; Vol. 27 (1), pp. 61. Date of Electronic Publication: 2020 May 08.
Typ publikacji:: Journal Article
MeSH Terms:: Blood-Brain Barrier/*physiology
Infarction, Middle Cerebral Artery/*pathology
Receptors, G-Protein-Coupled/*genetics
Signal Transduction/*genetics
Animals ; BRCA1 Protein/genetics ; BRCA1 Protein/metabolism ; Rats ; Rats, Sprague-Dawley ; Receptors, G-Protein-Coupled/metabolism ; Sirtuin 1/genetics ; Sirtuin 1/metabolism

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Skocz do pozycji: 13.

Tytuł:: Modulation of human platelet activation and in vivo vascular thrombosis by columbianadin: regulation by integrin α IIb β 3 inside-out but not outside-in signals.
Autorzy:: Hou SM; Department of Cardiovascular Center, Cathay General Hospital, No. 280 Renai Rd. Sec.4, Taipei, 106, Taiwan.; Division of Cardiovascular Surgery, Department of Surgery, School of Medicine, College of Medicine, Fu Jen Catholic University, No.510, Zhongzheng Rd, New Taipei City, 242, Taiwan.; Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, 250 Wu-Hsing Street, Taipei, 110, Taiwan.
Hsia CW; Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, 250 Wu-Hsing Street, Taipei, 110, Taiwan.
Tsai CL; Graduate Institute of Metabolism and Obesity Sciences, Collage of Nutrition, Taipei Medical University, No. 250, Wu Hsing St, Taipei, 110, Taiwan.
Hsia CH; Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, 250 Wu-Hsing Street, Taipei, 110, Taiwan.; Translational Medicine Center, Shin Kong Wu Ho-Su Memorial Hospital, No. 95, Wenchang Rd, Taipei, 111, Taiwan.
Jayakumar T; Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, 250 Wu-Hsing Street, Taipei, 110, Taiwan.
Velusamy M; Department of Chemistry, North Eastern Hill University, Shillong, 793022, India.
Sheu JR; Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, 250 Wu-Hsing Street, Taipei, 110, Taiwan. .; Pokaż więcej
Źródło:: Journal of biomedical science [J Biomed Sci] 2020 May 06; Vol. 27 (1), pp. 60. Date of Electronic Publication: 2020 May 06.
Typ publikacji:: Journal Article
MeSH Terms:: Coumarins/*pharmacology
Platelet Activation/*drug effects
Platelet Glycoprotein GPIIb-IIIa Complex/*metabolism
Protective Agents/*pharmacology
Signal Transduction/*drug effects
Thrombosis/*drug therapy
Animals ; Humans ; Mice

Czasopismo naukowe

na półce

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Skocz do pozycji: 14.

Tytuł:: Signaling in and out: long-noncoding RNAs in tumor hypoxia.
Autorzy:: Kuo TC; Institute of Molecular and Genomic Medicine, National Health Research Institutes, Zhunan, Miaoli County, 35053, Taiwan, ROC.
Kung HJ; Institute of Molecular and Genomic Medicine, National Health Research Institutes, Zhunan, Miaoli County, 35053, Taiwan, ROC.; Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei, 11031, Taiwan, ROC.; Ph.D. Program for Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei, 11031, Taiwan, ROC.; Department of Biochemistry and Molecular Medicine, Comprehensive Cancer Center, University of California at Davis, Sacramento, CA, 95817, USA.; TMU Research Center of Cancer Translational Medicine, Taipei Medical University, Taipei, 110, Taiwan, ROC.
Shih JW; Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei, 11031, Taiwan, ROC. .; Ph.D. Program for Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei, 11031, Taiwan, ROC. .; TMU Research Center of Cancer Translational Medicine, Taipei Medical University, Taipei, 110, Taiwan, ROC. .; Ph.D. Program for Translational Medicine, College of Medical Science and Technology, Taipei Medical University, Taipei, 11031, Taiwan, ROC. .; Pokaż więcej
Źródło:: Journal of biomedical science [J Biomed Sci] 2020 May 05; Vol. 27 (1), pp. 59. Date of Electronic Publication: 2020 May 05.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Signal Transduction*
Gene Expression Regulation, Neoplastic/*physiology
RNA, Long Noncoding/*genetics
Tumor Hypoxia/*genetics
Tumor Microenvironment/*physiology
RNA, Long Noncoding/metabolism

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Skocz do pozycji: 15.

Tytuł:: A novel c-Kit/phospho-prohibitin axis enhances ovarian cancer stemness and chemoresistance via Notch3-PBX1 and β-catenin-ABCG2 signaling.
Autorzy:: Fang CH; Agricultural Biotechnology Research Center, Academia Sinica, 128 Academia Rd, Sec. 2, Taipei, 11529, Taiwan.; Institute of Biotechnology, National Taiwan University, 4F, No. 81, Chang-Xing St, Taipei, 10672, Taiwan.
Lin YT; Agricultural Biotechnology Research Center, Academia Sinica, 128 Academia Rd, Sec. 2, Taipei, 11529, Taiwan.
Liang CM; Genomics Research Center, Academia Sinica, 128 Academia Rd, Sec. 2, Taipei, 11529, Taiwan.
Liang SM; Agricultural Biotechnology Research Center, Academia Sinica, 128 Academia Rd, Sec. 2, Taipei, 11529, Taiwan. .; Institute of Biotechnology, National Taiwan University, 4F, No. 81, Chang-Xing St, Taipei, 10672, Taiwan. .; Pokaż więcej
Źródło:: Journal of biomedical science [J Biomed Sci] 2020 Mar 13; Vol. 27 (1), pp. 42. Date of Electronic Publication: 2020 Mar 13.
Typ publikacji:: Journal Article
MeSH Terms:: Cell Proliferation*
Gene Expression Regulation, Neoplastic*
Drug Resistance, Neoplasm/*genetics
Ovarian Neoplasms/*genetics
Signal Transduction/*genetics
Cell Line, Tumor ; Female ; Humans ; Ovarian Neoplasms/physiopathology ; Prohibitins

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Skocz do pozycji: 16.

Tytuł:: Epigenetic regulation of epithelial-mesenchymal transition: focusing on hypoxia and TGF-β signaling.
Autorzy:: Lin YT; Cancer Genome Research Center, Chang Gung Memorial Hospital at Linkou, Gueishan Dist., Taoyuan, 333, Taiwan.
Wu KJ; Cancer Genome Research Center, Chang Gung Memorial Hospital at Linkou, Gueishan Dist., Taoyuan, 333, Taiwan. .; Institute of Cellular and Organismic Biology, Academia Sinica, Taipei, 115, Taiwan. .; Inst. of Clinical Medical Sciences, Chang Gung University, Taoyuan, 333, Taiwan. .; Pokaż więcej
Źródło:: Journal of biomedical science [J Biomed Sci] 2020 Mar 02; Vol. 27 (1), pp. 39. Date of Electronic Publication: 2020 Mar 02.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Epigenesis, Genetic*
Signal Transduction*
Epithelial-Mesenchymal Transition/*genetics
Hypoxia/*genetics
Transforming Growth Factor beta/*genetics
Humans ; Transforming Growth Factor beta/metabolism

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Skocz do pozycji: 17.

Tytuł:: Involvement of collagen XVII in pluripotency gene expression and metabolic reprogramming of lung cancer stem cells.
Autorzy:: Hsu HS; Division of Thoracic Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei, Taiwan.; Institute of Emergency and Critical Care Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan.
Liu CC; Institute of Emergency and Critical Care Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan.; Division of Traumatology, Emergency Department, Taipei Veterans General Hospital, Taipei, Taiwan.; Faculty of Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan.
Lin JH; Division of Thoracic Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei, Taiwan.; Institute of Emergency and Critical Care Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan.
Hsu TW; Division of Thoracic Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei, Taiwan.; Institute of Emergency and Critical Care Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan.
Hsu JW; Division of Traumatology, Emergency Department, Taipei Veterans General Hospital, Taipei, Taiwan.; Faculty of Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan.
Li AF; Faculty of Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan.; Department of Pathology and Laboratory Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.
Hung SC; Drug Development Center, Institute of New Drug Development, Institute of Biomedical Sciences, China Medical University, Taichung, 404, Taiwan. .; Integrative Stem Cell Center, Department of Orthopaedics, China Medical University Hospital, Taichung, 404, Taiwan. .; Institute of Biomedical Sciences, Academia Sinica, Taipei, 105, Taiwan. .; Pokaż więcej
Źródło:: Journal of biomedical science [J Biomed Sci] 2020 Jan 13; Vol. 27 (1), pp. 5. Date of Electronic Publication: 2020 Jan 13.
Typ publikacji:: Journal Article
MeSH Terms:: Cellular Reprogramming*
Gene Expression Regulation, Neoplastic*
Signal Transduction*
Autoantigens/*biosynthesis
Lung Neoplasms/*metabolism
Neoplasm Proteins/*biosynthesis
Neoplastic Stem Cells/*metabolism
Non-Fibrillar Collagens/*biosynthesis
Pluripotent Stem Cells/*metabolism
A549 Cells ; HT29 Cells ; Humans ; Lung Neoplasms/pathology ; Neoplastic Stem Cells/pathology ; Pluripotent Stem Cells/pathology ; Collagen Type XVII

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Skocz do pozycji: 18.

Tytuł:: Beyond defense: regulation of neuronal morphogenesis and brain functions via Toll-like receptors.
Autorzy:: Chen CY; Institute of Molecular Biology, Academia Sinica, 128, Academia Rd., Sec. 2, Taipei, 11529, Taiwan, Republic of China. .
Shih YC; Institute of Molecular Biology, Academia Sinica, 128, Academia Rd., Sec. 2, Taipei, 11529, Taiwan, Republic of China.
Hung YF; Institute of Molecular Biology, Academia Sinica, 128, Academia Rd., Sec. 2, Taipei, 11529, Taiwan, Republic of China.
Hsueh YP; Institute of Molecular Biology, Academia Sinica, 128, Academia Rd., Sec. 2, Taipei, 11529, Taiwan, Republic of China. .; Pokaż więcej
Źródło:: Journal of biomedical science [J Biomed Sci] 2019 Nov 04; Vol. 26 (1), pp. 90. Date of Electronic Publication: 2019 Nov 04.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Neurogenesis*
Brain/*physiology
Immunity, Innate/*genetics
Neurons/*physiology
Signal Transduction/*genetics
Toll-Like Receptors/*genetics
Animals ; Humans ; Mice

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Skocz do pozycji: 19.

Tytuł:: Cilostazol inhibits hyperglucose-induced vascular smooth muscle cell dysfunction by modulating the RAGE/ERK/NF-κB signaling pathways.
Autorzy:: Su SC; Division of Endocrinology and Metabolism, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.; Graduate Institute of Medical Sciences, National Defense Medical Center, Taipei, Taiwan.
Hung YJ; Division of Endocrinology and Metabolism, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan. .; Graduate Institute of Medical Sciences, National Defense Medical Center, Taipei, Taiwan. .; Division of Biochemistry, National Defense Medical Center, Taipei, Taiwan. .
Huang CL; Division of Endocrinology and Metabolism, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.; Graduate Institute of Medical Sciences, National Defense Medical Center, Taipei, Taiwan.
Shieh YS; School of Dentistry, National Defense Medical Center, Taipei, Taiwan.; Department of Oral Diagnosis and Pathology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.; Division of Biochemistry, National Defense Medical Center, Taipei, Taiwan.
Chien CY; Graduate Institute of Medical Sciences, National Defense Medical Center, Taipei, Taiwan.
Chiang CF; School of Dentistry, National Defense Medical Center, Taipei, Taiwan.; Graduate Institute of Medical Sciences, National Defense Medical Center, Taipei, Taiwan.
Liu JS; Division of Endocrinology and Metabolism, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Lu CH; Division of Endocrinology and Metabolism, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Hsieh CH; Division of Endocrinology and Metabolism, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Lin CM; Department of Pediatrics, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Lee CH; Division of Endocrinology and Metabolism, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan. .; Graduate Institute of Medical Sciences, National Defense Medical Center, Taipei, Taiwan. .; Division of Biochemistry, National Defense Medical Center, Taipei, Taiwan. .; Pokaż więcej
Źródło:: Journal of biomedical science [J Biomed Sci] 2019 Sep 06; Vol. 26 (1), pp. 68. Date of Electronic Publication: 2019 Sep 06.
Typ publikacji:: Journal Article
MeSH Terms:: Signal Transduction*
Cilostazol/*pharmacology
Diabetic Angiopathies/*drug therapy
Glucose/*adverse effects
Muscle, Smooth, Vascular/*drug effects
Phosphodiesterase 3 Inhibitors/*pharmacology
Animals ; MAP Kinase Signaling System ; Male ; Mice ; Mice, Inbred BALB C ; Muscle, Smooth, Vascular/physiopathology ; NF-kappa B/metabolism ; Rats ; Receptor for Advanced Glycation End Products/metabolism

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Skocz do pozycji: 20.

Tytuł:: Activation of TrkB/Akt signaling by a TrkB receptor agonist improves long-term histological and functional outcomes in experimental intracerebral hemorrhage.
Autorzy:: Wu CH; Graduate Institute of Life Sciences, National Defense Medical Center, Taipei, Taiwan.
Chen CC; Department of Physical Medicine and Rehabilitation, Cheng Hsin General Hospital, 45 Cheng Hsin Street, Taipei, Taiwan, Republic of China.; Graduate Institute of Gerontology and Health Care Management, Chang Gung University of Science and Technology, Taoyuan, Taiwan.
Hung TH; Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital at Taipei and College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Chuang YC; Department of Physiology and Biophysics, National Defense Medical Center, Taipei, Taiwan.
Chao M; School of Medicine, National Defense Medical Center, Taipei, Taiwan.
Shyue SK; Graduate Institute of Life Sciences, National Defense Medical Center, Taipei, Taiwan. .; Institute of Biomedical Sciences, Academia Sinica, 128 Academia Road, Section 2, Nankang, Taipei, Taiwan, Republic of China. .
Chen SF; Department of Physical Medicine and Rehabilitation, Cheng Hsin General Hospital, 45 Cheng Hsin Street, Taipei, Taiwan, Republic of China. .; Department of Physiology and Biophysics, National Defense Medical Center, Taipei, Taiwan. .; Pokaż więcej
Źródło:: Journal of biomedical science [J Biomed Sci] 2019 Jul 15; Vol. 26 (1), pp. 53. Date of Electronic Publication: 2019 Jul 15.
Typ publikacji:: Journal Article
MeSH Terms:: Cerebral Hemorrhage/*drug therapy
Flavones/*pharmacology
Membrane Glycoproteins/*agonists
Neuroprotective Agents/*pharmacology
Signal Transduction/*drug effects
Animals ; Cerebral Hemorrhage/chemically induced ; Collagenases/toxicity ; Injections, Intraperitoneal ; Male ; Mice ; Mice, Inbred C57BL ; Protein-Tyrosine Kinases ; Proto-Oncogene Proteins c-akt/genetics ; Proto-Oncogene Proteins c-akt/metabolism

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