Author Correction: Naturally-occurring cholesterol analogues in lipid nanoparticles induce polymorphic shape and enhance intracellular delivery of mRNA.
Autorzy:
Patel S; Department of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Robertson Life Sciences Building, 2730 Southwest Moody Avenue, Portland, OR, 97201, USA. Ashwanikumar N; Department of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Robertson Life Sciences Building, 2730 Southwest Moody Avenue, Portland, OR, 97201, USA. Robinson E; Department of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Robertson Life Sciences Building, 2730 Southwest Moody Avenue, Portland, OR, 97201, USA. Xia Y; Moderna Therapeutics, 200 Technology Square, Cambridge, MA, 02139, USA. Mihai C; Moderna Therapeutics, 200 Technology Square, Cambridge, MA, 02139, USA. Griffith JP 3rd; French Family Science Center, Department of Chemistry, 124 Science Drive, Duke University, Durham, NC, 27708, USA. Hou S; French Family Science Center, Department of Chemistry, 124 Science Drive, Duke University, Durham, NC, 27708, USA. Esposito AA; Moderna Therapeutics, 200 Technology Square, Cambridge, MA, 02139, USA. Ketova T; Moderna Therapeutics, 200 Technology Square, Cambridge, MA, 02139, USA. Welsher K; French Family Science Center, Department of Chemistry, 124 Science Drive, Duke University, Durham, NC, 27708, USA. JoyalJL; Moderna Therapeutics, 200 Technology Square, Cambridge, MA, 02139, USA. Almarsson Ö; Moderna Therapeutics, 200 Technology Square, Cambridge, MA, 02139, USA. Sahay G; Department of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Robertson Life Sciences Building, 2730 Southwest Moody Avenue, Portland, OR, 97201, USA. .; Department of Biomedical Engineering, Oregon Health and Science University, Robertson Life Science Building, 2730 Southwest Moody Avenue, Portland, OR, 97201, USA. .
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Źródło:
Nature communications [Nat Commun] 2020 Jul 06; Vol. 11 (1), pp. 3435. Date of Electronic Publication: 2020 Jul 06.
Impact of mRNA chemistry and manufacturing process on innate immune activation.
Autorzy:
Nelson J; Moderna Inc., 200 Technology Square, Cambridge, MA, USA. Sorensen EW; Moderna Inc., 200 Technology Square, Cambridge, MA, USA. Mintri S; Moderna Inc., 200 Technology Square, Cambridge, MA, USA. Rabideau AE; Moderna Inc., 200 Technology Square, Cambridge, MA, USA. Zheng W; Moderna Inc., 200 Technology Square, Cambridge, MA, USA. Besin G; Moderna Inc., 200 Technology Square, Cambridge, MA, USA. Khatwani N; Moderna Inc., 200 Technology Square, Cambridge, MA, USA. Su SV; Moderna Inc., 200 Technology Square, Cambridge, MA, USA. Miracco EJ; Moderna Inc., 200 Technology Square, Cambridge, MA, USA. Issa WJ; Moderna Inc., 200 Technology Square, Cambridge, MA, USA. Hoge S; Moderna Inc., 200 Technology Square, Cambridge, MA, USA. Stanton MG; Moderna Inc., 200 Technology Square, Cambridge, MA, USA. JoyalJL; Moderna Inc., 200 Technology Square, Cambridge, MA, USA.
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Źródło:
Science advances [Sci Adv] 2020 Jun 24; Vol. 6 (26), pp. eaaz6893. Date of Electronic Publication: 2020 Jun 24 (Print Publication: 2020).
Naturally-occurring cholesterol analogues in lipid nanoparticles induce polymorphic shape and enhance intracellular delivery of mRNA.
Autorzy:
Patel S; Department of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Robertson Life Sciences Building, 2730 Southwest Moody Avenue, Portland, OR, 97201, USA. Ashwanikumar N; Department of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Robertson Life Sciences Building, 2730 Southwest Moody Avenue, Portland, OR, 97201, USA. Robinson E; Department of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Robertson Life Sciences Building, 2730 Southwest Moody Avenue, Portland, OR, 97201, USA. Xia Y; Moderna Therapeutics, 200 Technology Square, Cambridge, MA, 02139, USA. Mihai C; Moderna Therapeutics, 200 Technology Square, Cambridge, MA, 02139, USA. Griffith JP 3rd; French Family Science Center, Department of Chemistry, 124 Science Drive, Duke University, Durham, NC, 27708, USA. Hou S; French Family Science Center, Department of Chemistry, 124 Science Drive, Duke University, Durham, NC, 27708, USA. Esposito AA; Moderna Therapeutics, 200 Technology Square, Cambridge, MA, 02139, USA. Ketova T; Moderna Therapeutics, 200 Technology Square, Cambridge, MA, 02139, USA. Welsher K; French Family Science Center, Department of Chemistry, 124 Science Drive, Duke University, Durham, NC, 27708, USA. JoyalJL; Moderna Therapeutics, 200 Technology Square, Cambridge, MA, 02139, USA. Almarsson Ö; Moderna Therapeutics, 200 Technology Square, Cambridge, MA, 02139, USA. Sahay G; Department of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Robertson Life Sciences Building, 2730 Southwest Moody Avenue, Portland, OR, 97201, USA. .; Department of Biomedical Engineering, Oregon Health and Science University, Robertson Life Science Building, 2730 Southwest Moody Avenue, Portland, OR, 97201, USA. .
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Źródło:
Nature communications [Nat Commun] 2020 Feb 20; Vol. 11 (1), pp. 983. Date of Electronic Publication: 2020 Feb 20.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Triazole Appending Agent (TAAG): A New Synthon for Preparing Iodine-Based Molecular Imaging and Radiotherapy Agents.
Autorzy:
Darwish A; Department of Chemistry and Chemical Biology, McMaster University , 1280 Main Street West, Hamilton, Ontario L8S 4L8, Canada. Blacker M; Centre for Probe Development and Commercialization, McMaster University , 1280 Main Street West Hamilton, Ontario L8S 4K1, Canada. Janzen N; Department of Chemistry and Chemical Biology, McMaster University , 1280 Main Street West, Hamilton, Ontario L8S 4L8, Canada. Rathmann SM; Department of Chemistry and Chemical Biology, McMaster University , 1280 Main Street West, Hamilton, Ontario L8S 4L8, Canada. Czorny S; Department of Chemistry and Chemical Biology, McMaster University , 1280 Main Street West, Hamilton, Ontario L8S 4L8, Canada. Hillier SM; Molecular Insight Pharmaceuticals , 160 Second Street, Cambridge, Massachusetts 02142, United States. JoyalJL; Molecular Insight Pharmaceuticals , 160 Second Street, Cambridge, Massachusetts 02142, United States. Babich JW; Molecular Insight Pharmaceuticals , 160 Second Street, Cambridge, Massachusetts 02142, United States. Valliant JF; Department of Chemistry and Chemical Biology, McMaster University , 1280 Main Street West, Hamilton, Ontario L8S 4L8, Canada.
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Źródło:
ACS medicinal chemistry letters [ACS Med Chem Lett] 2012 Feb 18; Vol. 3 (4), pp. 313-6. Date of Electronic Publication: 2012 Feb 18 (Print Publication: 2012).
Olanzapine promotes fat accumulation in male rats by decreasing physical activity, repartitioning energy and increasing adipose tissue lipogenesis while impairing lipolysis.
Novel polar single amino acid chelates for technetium-99m tricarbonyl-based radiopharmaceuticals with enhanced renal clearance: application to octreotide.
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