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Wyszukujesz frazę ""KIDNEY tubules"" wg kryterium: Temat


Tytuł :
Serum Protein Exposure Activates a Core Regulatory Program Driving Human Proximal Tubule Injury.
Autorzy :
Lidberg KA; Department of Pharmaceutics, University of Washington, Seattle, Washington.
Muthusamy S; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington.
Adil M; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington.
Mahadeo A; Department of Pharmaceutics, University of Washington, Seattle, Washington.
Yang J; Department of Pharmaceutics, University of Washington, Seattle, Washington.
Patel RS; Seattle Children's Hospital, Seattle, Washington.
Wang L; Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington.
Bammler TK; Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington.
Reichel J; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington.
Yeung CK; Department of Pharmacy, University of Washington, Seattle, Washington.; Kidney Research Institute, Seattle, Washington.
Himmelfarb J; Kidney Research Institute, Seattle, Washington.; Nephrology Division, Department of Medicine, University of Washington, Seattle, Washington.
Kelly EJ; Department of Pharmaceutics, University of Washington, Seattle, Washington .; Kidney Research Institute, Seattle, Washington.
Akilesh S; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington .; Kidney Research Institute, Seattle, Washington.
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Źródło :
Journal of the American Society of Nephrology : JASN [J Am Soc Nephrol] 2022 May; Vol. 33 (5), pp. 949-965. Date of Electronic Publication: 2022 Feb 23.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Kidney Diseases*/metabolism
Kidney Tubules, Proximal*/metabolism
Animals ; Blood Proteins ; Female ; Humans ; Kidney Tubules/metabolism ; Male ; Proteinuria/metabolism
Czasopismo naukowe
Tytuł :
'Hybrid' oncocytoma: collecting duct (Bellini) carcinoma-the peril from this extremely rare intratumoural coexistence.
Autorzy :
Tsikopoulos I; Urology Department, 424 General Military Training Hospital, Thessaloniki, Greece.
Papadopoulos DI; Urology Department, Surgical Division, West Middlesex University Hospital, Isleworth, UK .
Charitopoulos K; Urology Department, Surgical Division, West Middlesex University Hospital, Isleworth, UK.
Gkekas C; Urology Department, 424 General Military Training Hospital, Thessaloniki, Greece.
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Źródło :
BMJ case reports [BMJ Case Rep] 2021 Apr 26; Vol. 14 (4). Date of Electronic Publication: 2021 Apr 26.
Typ publikacji :
Journal Article
MeSH Terms :
Adenoma, Oxyphilic*/diagnostic imaging
Carcinoma*
Carcinoma, Renal Cell*
Kidney Neoplasms*/diagnostic imaging
Kidney Tubules, Collecting*
Humans ; Kidney Tubules ; Nephrectomy
Czasopismo naukowe
Tytuł :
Adenosine A1 Receptor Deficiency Aggravates Extracellular Matrix Accumulation in Diabetic Nephropathy through Disturbance of Peritubular Microenvironment.
Autorzy :
Tian D; Department of Nephrology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100730, China.
Li J; Department of Nephrology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100730, China.
Zou L; Department of Nephrology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100730, China.
Lin M; Department of Nephrology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100730, China.
Shi X; Department of Nephrology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100730, China.
Hu Y; Department of Nephrology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100730, China.
Lang J; Department of Nephrology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100730, China.
Xu L; Department of Nephrology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100730, China.
Ye W; Department of Nephrology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100730, China.
Li X; Department of Nephrology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100730, China.
Chen L; Department of Nephrology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100730, China.
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Źródło :
Journal of diabetes research [J Diabetes Res] 2021 Oct 11; Vol. 2021, pp. 5584871. Date of Electronic Publication: 2021 Oct 11 (Print Publication: 2021).
Typ publikacji :
Journal Article
MeSH Terms :
Diabetes Mellitus, Experimental/*metabolism
Diabetic Nephropathies/*genetics
Extracellular Matrix/*metabolism
Kidney Tubules/*metabolism
Receptor, Adenosine A1/*genetics
Animals ; Antigens, CD34/metabolism ; Cell Line ; Cellular Microenvironment ; Diabetic Nephropathies/metabolism ; Diabetic Nephropathies/pathology ; Extracellular Matrix/pathology ; Fibrosis ; Humans ; Kidney Tubules/pathology ; Kidney Tubules, Proximal/cytology ; Kidney Tubules, Proximal/metabolism ; Mice ; Mice, Knockout ; Receptor, Adenosine A1/metabolism ; Receptor, Platelet-Derived Growth Factor beta/metabolism ; Transforming Growth Factor beta/metabolism
Czasopismo naukowe
Tytuł :
Protein interactions with metallothionein-3 promote vectorial active transport in human proximal tubular cells.
Autorzy :
Kalyan G; Department of Pathology, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, ND, United States of America.
Slusser-Nore A; Department of Pathology, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, ND, United States of America.
Dunlevy JR; Department of Biomedical Sciences, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, ND, United States of America.
Bathula CS; Department of Pathology, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, ND, United States of America.
Shabb JB; Department of Biomedical Sciences, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, ND, United States of America.
Muhonen W; Department of Biomedical Sciences, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, ND, United States of America.
Somji S; Department of Pathology, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, ND, United States of America.
Sens DA; Department of Pathology, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, ND, United States of America.
Garrett SH; Department of Pathology, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, ND, United States of America.
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Źródło :
PloS one [PLoS One] 2022 May 03; Vol. 17 (5), pp. e0267599. Date of Electronic Publication: 2022 May 03 (Print Publication: 2022).
Typ publikacji :
Journal Article
MeSH Terms :
Biological Transport, Active*
Kidney Tubules, Proximal*/cytology
Kidney Tubules, Proximal*/metabolism
Metallothionein 3*
Epithelial Cells/metabolism ; Humans ; Molecular Docking Simulation ; RNA, Messenger/genetics
Czasopismo naukowe
Tytuł :
Immunosuppressive calcineurin inhibitor cyclosporine A induces proapoptotic endoplasmic reticulum stress in renal tubular cells.
Autorzy :
Yilmaz DE; Institute of Functional Anatomy, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Kirschner K; Institute of Vegetative Physiology, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Demirci H; Institute of Functional Anatomy, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Himmerkus N; Institute of Physiology, Christian-Albrecht-University Kiel, Kiel, Germany.
Bachmann S; Institute of Functional Anatomy, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Mutig K; Institute of Vegetative Physiology, Charité-Universitätsmedizin Berlin, Berlin, Germany; Department of Pharmacology, I.M. Sechenov First Moscow State Medical University of the Ministry of Healthcare of the Russian Federation (Sechenov University), Moscow, Russia. Electronic address: .
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2022 Mar; Vol. 298 (3), pp. 101589. Date of Electronic Publication: 2022 Jan 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Calcineurin Inhibitors*/pharmacology
Cyclosporine*/pharmacology
Endoplasmic Reticulum Stress*/drug effects
Kidney Tubules*/drug effects
Kidney Tubules*/immunology
Animals ; Calcineurin/metabolism ; Cyclophilins/metabolism ; HEK293 Cells ; Humans ; Immunosuppressive Agents/pharmacology ; Protein Kinases ; RNA ; Rats ; Tacrolimus/pharmacology ; Unfolded Protein Response
Czasopismo naukowe
Tytuł :
Oxidized alkyl phospholipids stimulate sodium transport in proximal tubules via a nongenomic PPARγ-dependent pathway.
Autorzy :
Mizuno T; Division of Nephrology and Endocrinology, The University of Tokyo, Tokyo, Japan.
Satoh N; Division of Nephrology and Endocrinology, The University of Tokyo, Tokyo, Japan.
Horita S; Division of Nephrology and Endocrinology, The University of Tokyo, Tokyo, Japan.
Tsukada H; Division of Nephrology and Endocrinology, The University of Tokyo, Tokyo, Japan.
Takagi M; Division of Nephrology and Endocrinology, The University of Tokyo, Tokyo, Japan.
Sato Y; Department of Urology, The University of Tokyo, Tokyo, Japan.
Kume H; Department of Urology, The University of Tokyo, Tokyo, Japan.
Nangaku M; Division of Nephrology and Endocrinology, The University of Tokyo, Tokyo, Japan.
Nakamura M; Division of Nephrology and Endocrinology, The University of Tokyo, Tokyo, Japan. Electronic address: .
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2022 Mar; Vol. 298 (3), pp. 101681. Date of Electronic Publication: 2022 Feb 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Kidney Tubules, Proximal*/drug effects
Kidney Tubules, Proximal*/metabolism
PPAR gamma*/metabolism
Phospholipids*/metabolism
Sodium-Hydrogen Exchangers*/metabolism
Animals ; CD36 Antigens/antagonists & inhibitors ; CD36 Antigens/metabolism ; Hypoglycemic Agents/pharmacology ; Oxidation-Reduction ; Rats ; Signal Transduction ; Thiazolidinediones/pharmacology
Czasopismo naukowe
Tytuł :
ClC-K2 Cl channel allows identification of A- and B-type of intercalated cells in split-opened collecting ducts.
Autorzy :
Pyrshev K; Department of Integrative Biology and Pharmacology, the University of Texas Health Science Center at Houston, Houston, Texas, USA.
Khayyat NH; Department of Integrative Biology and Pharmacology, the University of Texas Health Science Center at Houston, Houston, Texas, USA.
Stavniichuk A; Department of Integrative Biology and Pharmacology, the University of Texas Health Science Center at Houston, Houston, Texas, USA.
Tomilin VN; Department of Integrative Biology and Pharmacology, the University of Texas Health Science Center at Houston, Houston, Texas, USA.
Zaika O; Department of Integrative Biology and Pharmacology, the University of Texas Health Science Center at Houston, Houston, Texas, USA.
Ramkumar N; Division of Nephrology and Hypertension, University of Utah Health, Salt Lake City, Utah, USA.
Pochynyuk O; Department of Integrative Biology and Pharmacology, the University of Texas Health Science Center at Houston, Houston, Texas, USA.
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Źródło :
FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2022 May; Vol. 36 (5), pp. e22275.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Acidosis*/metabolism
Kidney Tubules, Collecting*/metabolism
Animals ; Anion Transport Proteins/genetics ; Anion Transport Proteins/metabolism ; Mice ; Nephrons/metabolism ; Sulfate Transporters/metabolism
Czasopismo naukowe
Tytuł :
Cubilin and amnionless protein are novel target antigens in anti-brush border antibody disease.
Autorzy :
Morelle J; Division of Nephrology, Cliniques universitaires Saint-Luc, Brussels, Belgium; Institute for Experimental and Clinical Research, UCLouvain, Brussels, Belgium. Electronic address: .
Caza T; Arkana Laboratories, Little Rock, Arkansas, USA.
Debiec H; Sorbonne Université and Institut National de la Santé et de la Recherche Médicale, Unité Mixte de Recherche S 1155, Paris, France.
Aydin S; Institute for Experimental and Clinical Research, UCLouvain, Brussels, Belgium; Department of Pathology, Cliniques universitaires Saint-Luc, Brussels, Belgium.
Storey A; University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Ronco P; Sorbonne Université and Institut National de la Santé et de la Recherche Médicale, Unité Mixte de Recherche S 1155, Paris, France; Department of Nephrology, Centre Hospitalier du Mans, Le Mans, France.
Larsen C; Arkana Laboratories, Little Rock, Arkansas, USA. Electronic address: .
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Źródło :
Kidney international [Kidney Int] 2022 May; Vol. 101 (5), pp. 1063-1068. Date of Electronic Publication: 2022 Mar 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Kidney Tubules, Proximal*/metabolism
Receptors, Cell Surface*/metabolism
Czasopismo naukowe
Tytuł :
Identification of multinucleated cells in human kidney cortex: A way for tissue repairing?
Autorzy :
Fantone S; Department of Experimental and Clinical Medicine, Section of Neuroscience and Cell Biology, School of Medicine, Università Politecnica delle Marche, Ancona, Italy.
Tossetta G; Department of Experimental and Clinical Medicine, Section of Neuroscience and Cell Biology, School of Medicine, Università Politecnica delle Marche, Ancona, Italy.
Graciotti L; Department of Clinical and Molecular Sciences, Section of Experimental Pathology, Università Politecnica delle Marche, Ancona, Italy.
Galosi AB; Division of Urology, Department of Clinical and Specialist Sciences, Università Politecnica delle Marche, Azienda Ospedaliero-Universitaria Ospedali Riuniti, Ancona, Italy.
Skrami E; Centre of Epidemiology and Biostatistics, Università Politecnica delle Marche, Ancona, Italy.
Marzioni D; Department of Experimental and Clinical Medicine, Section of Neuroscience and Cell Biology, School of Medicine, Università Politecnica delle Marche, Ancona, Italy.
Morroni M; Department of Experimental and Clinical Medicine, Section of Neuroscience and Cell Biology, School of Medicine, Università Politecnica delle Marche, Ancona, Italy.; Electron Microscopy Unit, Azienda Ospedaliero-Universitaria Ospedali Riuniti, Ancona, Italy.
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Źródło :
Journal of anatomy [J Anat] 2022 May; Vol. 240 (5), pp. 985-990. Date of Electronic Publication: 2021 Nov 15.
Typ publikacji :
Journal Article
MeSH Terms :
Kidney*
Kidney Tubules, Proximal*
Humans ; Kidney Cortex ; Microscopy, Electron
Czasopismo naukowe
Tytuł :
Antigen Cross-Presentation by Murine Proximal Tubular Epithelial Cells Induces Cytotoxic and Inflammatory CD8 T Cells.
Autorzy :
Linke A; Institute of Experimental Immunology and Hepatology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Cicek H; Institute of Experimental Immunology and Hepatology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Müller A; Institute of Experimental Immunology and Hepatology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.; Hamburg Center for Translational Immunology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Meyer-Schwesinger C; Institute of Cellular and Integrative Physiology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Melderis S; Hamburg Center for Translational Immunology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.; III. Medical Clinic, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Wiech T; Institute of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Wegscheid C; Institute of Experimental Immunology and Hepatology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Ridder J; Institute of Experimental Immunology and Hepatology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Steinmetz OM; Hamburg Center for Translational Immunology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.; III. Medical Clinic, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Diehl L; Institute of Experimental Immunology and Hepatology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.; Hamburg Center for Translational Immunology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Tiegs G; Institute of Experimental Immunology and Hepatology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.; Hamburg Center for Translational Immunology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Neumann K; Institute of Experimental Immunology and Hepatology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.; Hamburg Center for Translational Immunology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
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Źródło :
Cells [Cells] 2022 Apr 30; Vol. 11 (9). Date of Electronic Publication: 2022 Apr 30.
Typ publikacji :
Journal Article
MeSH Terms :
CD8-Positive T-Lymphocytes*
Kidney Tubules, Proximal*/metabolism
Animals ; Antigen Presentation ; Cross-Priming ; Epithelial Cells/metabolism ; Mice
Czasopismo naukowe
Tytuł :
Assessing proteinuria: value added from a mathematical model.
Autorzy :
Weinstein AM; Department of Medicine, Department of Physiology and Biophysics, Weill Medical College of Cornell University, New York, NY, USA.
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Źródło :
The Journal of physiology [J Physiol] 2022 Apr; Vol. 600 (8), pp. 1817-1818. Date of Electronic Publication: 2022 Mar 12.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Kidney Tubules, Proximal*
Proteinuria*
Female ; Glomerular Filtration Rate ; Humans ; Male ; Models, Theoretical
Czasopismo naukowe
Tytuł :
New Insights into the Pivotal Roles of Claudins in Proximal Tubule Electrolyte Reabsorption.
Autorzy :
Aronson PS; Departments of Internal Medicine and of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, Connecticut .
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Źródło :
Journal of the American Society of Nephrology : JASN [J Am Soc Nephrol] 2022 Apr; Vol. 33 (4), pp. 659-661. Date of Electronic Publication: 2022 Mar 09.
Typ publikacji :
Editorial; Research Support, N.I.H., Extramural
MeSH Terms :
Claudins*/metabolism
Kidney Tubules, Proximal*/metabolism
Electrolytes/metabolism ; Renal Reabsorption ; Tight Junctions
Raport
Tytuł :
HDAC3 inhibition improves urinary-concentrating defect in hypokalaemia by promoting AQP2 transcription.
Autorzy :
Xu L; Institute of Hypertension, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.; Department of Physiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
Xie H; Institute of Hypertension, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.; Department of Physiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
Hu S; Institute of Hypertension, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.; The School of Basic Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China.
Zhao X; Institute of Hypertension, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.; Department of Pathophysiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
Han M; Institute of Hypertension, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.; Department of Physiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
Liu Q; Institute of Hypertension, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.; Department of Physiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
Feng P; Department of Clinical Laboratory, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Wang W; Institute of Hypertension, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.; Department of Pathophysiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.; Department of Nephrology, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, China.
Li C; Institute of Hypertension, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.; Department of Physiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
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Źródło :
Acta physiologica (Oxford, England) [Acta Physiol (Oxf)] 2022 Apr; Vol. 234 (4), pp. e13802. Date of Electronic Publication: 2022 Feb 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Hypokalemia*/metabolism
Kidney Tubules, Collecting*/metabolism
Animals ; Aquaporin 2/genetics ; Aquaporin 2/metabolism ; Histone Deacetylase Inhibitors/metabolism ; Histone Deacetylase Inhibitors/pharmacology ; Male ; Mice ; Potassium/metabolism ; RNA, Messenger/metabolism ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Functional role of histamine receptors in the renal cortical collecting duct cells.
Autorzy :
Sudarikova AV; Division of Nephrology, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina.; Institute of Cytology, Russian Academy of Sciences, St. Petersburg, Russia.
Fomin MV; Department of Physiology, Augusta University, Augusta, Georgia.
Sultanova RF; Division of Nephrology, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina.
Zhao Y; Division of Nephrology, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina.
Perez S; Division of Nephrology, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina.
Domondon M; Division of Nephrology, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina.
Shamatova M; Institute of Cytology, Russian Academy of Sciences, St. Petersburg, Russia.; Department of Physiology, Augusta University, Augusta, Georgia.
Lysikova DV; Institute of Cytology, Russian Academy of Sciences, St. Petersburg, Russia.; Department of Physiology, Augusta University, Augusta, Georgia.
Spires DR; Department of Physiology, Augusta University, Augusta, Georgia.
Ilatovskaya DV; Department of Physiology, Augusta University, Augusta, Georgia.
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Źródło :
American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2022 Apr 01; Vol. 322 (4), pp. C775-C786. Date of Electronic Publication: 2022 Jan 26.
Typ publikacji :
Journal Article
MeSH Terms :
Epithelial Sodium Channels*/metabolism
Kidney Tubules, Collecting*/metabolism
Animals ; Mice ; Nephrons/metabolism ; Receptors, Histamine/genetics ; Receptors, Histamine/metabolism ; Sodium/metabolism
Czasopismo naukowe
Tytuł :
Modelling normal and nephrotic axial uptake of albumin and other filtered proteins along the proximal tubule.
Autorzy :
Edwards A; Department of Biomedical Engineering, Boston University, Boston, MA, USA.
Long KR; Renal-Electrolyte Division, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Baty CJ; Renal-Electrolyte Division, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Shipman KE; Renal-Electrolyte Division, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Weisz OA; Renal-Electrolyte Division, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
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Źródło :
The Journal of physiology [J Physiol] 2022 Apr; Vol. 600 (8), pp. 1933-1952. Date of Electronic Publication: 2022 Mar 02.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Kidney Tubules, Proximal*/metabolism
Low Density Lipoprotein Receptor-Related Protein-2*/metabolism
Albumins/metabolism ; Animals ; Endocytosis/physiology ; Female ; Humans ; Immunoglobulin G/metabolism ; Ligands ; Male ; Mice ; Proteinuria/metabolism
Czasopismo naukowe
Tytuł :
Impact of Membrane Voltage on Formation and Stability of Human Renal Proximal Tubules in Vitro .
Autorzy :
Adelfio M; Department of Biomedical Engineering, Tufts University, 4 Colby Street, Medford 02155, Massachusetts, United States.
Bonzanni M; Department of Biomedical Engineering, Tufts University, 4 Colby Street, Medford 02155, Massachusetts, United States.
Levin M; Biology Department, and Allen Discovery Center at Tufts University, Tufts University, 200 Boston Avenue, Medford 02155, Massachusetts, United States.
Kaplan DL; Department of Biomedical Engineering, Tufts University, 4 Colby Street, Medford 02155, Massachusetts, United States.
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Źródło :
ACS biomaterials science & engineering [ACS Biomater Sci Eng] 2022 Mar 14; Vol. 8 (3), pp. 1239-1246. Date of Electronic Publication: 2022 Feb 14.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Kidney Tubules, Proximal*/metabolism
Renal Insufficiency, Chronic*/metabolism
Adenosine Triphosphate/metabolism ; Female ; Humans ; Kidney ; Male ; Tissue Engineering/methods
Czasopismo naukowe
Tytuł :
KLF6 Promotes Pyroptosis of Renal Tubular Epithelial Cells in Septic Acute Kidney Injury.
Autorzy :
Gao M; Department of Critical Care Medicine, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Li H
Liu Q
Ma N
Zi P
Shi H
Du Y
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Źródło :
Shock (Augusta, Ga.) [Shock] 2022 Mar 01; Vol. 57 (3), pp. 417-426.
Typ publikacji :
Journal Article
MeSH Terms :
Acute Kidney Injury/*etiology
Epithelial Cells/*metabolism
Kidney Tubules/*metabolism
Kruppel-Like Factor 6/*physiology
Pyroptosis/*physiology
Sepsis/*complications
Aged ; Animals ; Case-Control Studies ; Disease Models, Animal ; Female ; Humans ; Kidney Tubules/pathology ; Male ; Mice ; Mice, Inbred C57BL ; MicroRNAs/physiology ; Middle Aged ; Oxidative Stress/physiology ; Sepsis/metabolism ; Sepsis/pathology
Czasopismo naukowe
Tytuł :
Three dimensional modeling of biologically relevant fluid shear stress in human renal tubule cells mimics in vivo transcriptional profiles.
Autorzy :
Ross EJ; Department of Chemical and Physical Biology, Vanderbilt University, Nashville, TN, 37235, USA.; HudsonAlpha Institute for Biotechnology, Huntsville, AL, 35806, USA.
Gordon ER; HudsonAlpha Institute for Biotechnology, Huntsville, AL, 35806, USA.
Sothers H; Department of Biological Sciences, The University of Alabama in Huntsville, Huntsville, AL, 35899, USA.
Darji R; HudsonAlpha Institute for Biotechnology, Huntsville, AL, 35806, USA.; Department of Biostatistics, Rollins School of Public Health, Emory University, Atlanta, GA, 30329, USA.
Baron O; HudsonAlpha Institute for Biotechnology, Huntsville, AL, 35806, USA.
Haithcock D; Biomedical and Life Sciences Division, CFD Research, Huntsville, AL, 35806, USA.
Prabhakarpandian B; Biomedical and Life Sciences Division, CFD Research, Huntsville, AL, 35806, USA.
Pant K; Biomedical and Life Sciences Division, CFD Research, Huntsville, AL, 35806, USA.
Myers RM; HudsonAlpha Institute for Biotechnology, Huntsville, AL, 35806, USA.
Cooper SJ; HudsonAlpha Institute for Biotechnology, Huntsville, AL, 35806, USA. .
Cox NJ; Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA. .; Vanderbilt Genetics Institute, Nashville, TN, USA. .
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Źródło :
Scientific reports [Sci Rep] 2021 Jul 07; Vol. 11 (1), pp. 14053. Date of Electronic Publication: 2021 Jul 07.
Typ publikacji :
Journal Article
MeSH Terms :
Models, Biological*
Stress, Mechanical*
Transcriptome*
Epithelial Cells/*metabolism
Kidney Tubules/*cytology
Biological Transport ; Biomarkers ; Computational Biology/methods ; Endocytosis/genetics ; Gene Expression Profiling ; Gene Expression Regulation ; Humans ; Kidney Tubules, Proximal/cytology ; Shear Strength ; Signal Transduction
Czasopismo naukowe
Tytuł :
Adenine overload induces ferroptosis in human primary proximal tubular epithelial cells.
Autorzy :
Khan MA; NHMRC CKD CRE (CKD.QLD), University of Queensland, Brisbane, Australia.; School of Biomedical Sciences, Faculty of Medicine, University of Queensland, Brisbane, Australia.; Conjoint Internal Medicine Laboratory, Chemical Pathology, Pathology Queensland, Brisbane, Australia.; Kidney Health Service, Royal Brisbane and Women's Hospital, Brisbane, Australia.; Kidney Disease Research Collaborative, Princess Alexandra Hospital and University of Queensland, Translational Research Institute, Brisbane, Australia.; Department of Pharmacy, Bangabandhu Sheikh Mujibur Rahman Science and Technology University, Gopalganj-8100, Dhaka, Bangladesh.
Nag P; Conjoint Internal Medicine Laboratory, Chemical Pathology, Pathology Queensland, Brisbane, Australia.; Kidney Health Service, Royal Brisbane and Women's Hospital, Brisbane, Australia.
Grivei A; Conjoint Internal Medicine Laboratory, Chemical Pathology, Pathology Queensland, Brisbane, Australia.; Kidney Health Service, Royal Brisbane and Women's Hospital, Brisbane, Australia.
Giuliani KTK; School of Biomedical Sciences, Faculty of Medicine, University of Queensland, Brisbane, Australia.; Conjoint Internal Medicine Laboratory, Chemical Pathology, Pathology Queensland, Brisbane, Australia.; Kidney Health Service, Royal Brisbane and Women's Hospital, Brisbane, Australia.
Wang X; Conjoint Internal Medicine Laboratory, Chemical Pathology, Pathology Queensland, Brisbane, Australia.; Kidney Health Service, Royal Brisbane and Women's Hospital, Brisbane, Australia.
Diwan V; NHMRC CKD CRE (CKD.QLD), University of Queensland, Brisbane, Australia.; Centre for Chronic Disease, Faculty of Medicine, University of Queensland, Brisbane, Australia.
Hoy W; NHMRC CKD CRE (CKD.QLD), University of Queensland, Brisbane, Australia.; Centre for Chronic Disease, Faculty of Medicine, University of Queensland, Brisbane, Australia.
Healy H; NHMRC CKD CRE (CKD.QLD), University of Queensland, Brisbane, Australia.; Conjoint Internal Medicine Laboratory, Chemical Pathology, Pathology Queensland, Brisbane, Australia.; Kidney Health Service, Royal Brisbane and Women's Hospital, Brisbane, Australia.; Centre for Chronic Disease, Faculty of Medicine, University of Queensland, Brisbane, Australia.
Gobe G; NHMRC CKD CRE (CKD.QLD), University of Queensland, Brisbane, Australia.; School of Biomedical Sciences, Faculty of Medicine, University of Queensland, Brisbane, Australia.; Kidney Disease Research Collaborative, Princess Alexandra Hospital and University of Queensland, Translational Research Institute, Brisbane, Australia.; Centre for Chronic Disease, Faculty of Medicine, University of Queensland, Brisbane, Australia.
Kassianos AJ; Conjoint Internal Medicine Laboratory, Chemical Pathology, Pathology Queensland, Brisbane, Australia. .; Kidney Health Service, Royal Brisbane and Women's Hospital, Brisbane, Australia. .; Centre for Chronic Disease, Faculty of Medicine, University of Queensland, Brisbane, Australia. .
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Źródło :
Cell death & disease [Cell Death Dis] 2022 Feb 02; Vol. 13 (2), pp. 104. Date of Electronic Publication: 2022 Feb 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adenine/*adverse effects
Epithelial Cells/*pathology
Ferroptosis/*drug effects
Kidney Tubules, Proximal/*pathology
Adenine/metabolism ; Aldehydes/metabolism ; Animals ; Epithelial Cells/drug effects ; Epithelial Cells/metabolism ; Flavanones/pharmacology ; Humans ; Iron/metabolism ; Kidney Diseases/chemically induced ; Kidney Diseases/metabolism ; Kidney Diseases/pathology ; Kidney Tubules, Proximal/drug effects ; Kidney Tubules, Proximal/metabolism ; Lipid Peroxidation/drug effects ; Mitochondria/drug effects ; Mitochondria/metabolism ; Rats ; Superoxide Dismutase/metabolism
Czasopismo naukowe
Tytuł :
A Heartwarming Role of the Proximal Tubules.
Autorzy :
Granda ML; Division of Nephrology, Kidney Research Institute, Seattle, Washington.
Kestenbaum B; Division of Nephrology, Kidney Research Institute, Seattle, Washington .
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Źródło :
Clinical journal of the American Society of Nephrology : CJASN [Clin J Am Soc Nephrol] 2022 Feb; Vol. 17 (2), pp. 182-183.
Typ publikacji :
Editorial; Comment
MeSH Terms :
Kidney*
Kidney Tubules, Proximal*
Humans
Opinia redakcyjna

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