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Tytuł :
Improved procedures and comparative results for video-assisted thoracoscopic extended thymectomy for myasthenia gravis.
Autorzy :
Nakagiri T; Department of General Thoracic Surgery, Osaka University Graduate School of Medicine, 2-2 L5 Yamadaoka, Suita, Osaka, 565-0871, Japan, .
Inoue M
Shintani Y
Funaki S
Kawamura T
Minami M
Ohta M
Kadota Y
Shiono H
Okumura M
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Źródło :
Surgical endoscopy [Surg Endosc] 2015 Sep; Vol. 29 (9), pp. 2859-65. Date of Electronic Publication: 2014 Dec 09.
Typ publikacji :
Comparative Study; Evaluation Study; Journal Article
MeSH Terms :
Myasthenia Gravis/*surgery
Thoracic Surgery, Video-Assisted/*methods
Thymectomy/*methods
Thymoma/*surgery
Adolescent ; Adult ; Aged ; Female ; Humans ; Male ; Middle Aged ; Myasthenia Gravis/complications ; Thymoma/complications ; Treatment Outcome ; Young Adult
Czasopismo naukowe
Tytuł :
Does gefitinib have effects on EGFR mutation-positive thymoma? -Case report of thymoma recurrence.
Autorzy :
Nakagiri T; Department of General Thoracic Surgery, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
Funaki S
Kadota Y
Takeuchi Y
Shiono H
Akashi A
Okumura M
Pokaż więcej
Źródło :
Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia [Ann Thorac Cardiovasc Surg] 2014; Vol. 20 Suppl, pp. 674-6. Date of Electronic Publication: 2014 Feb 04.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Antineoplastic Agents/*therapeutic use
Quinazolines/*therapeutic use
Thymoma/*drug therapy
Thymoma/*surgery
Thymus Neoplasms/*drug therapy
Thymus Neoplasms/*surgery
Combined Modality Therapy ; ErbB Receptors/genetics ; Fatal Outcome ; Female ; Gefitinib ; Humans ; Middle Aged ; Neoplasm Invasiveness ; Neoplasm Recurrence, Local ; Reoperation ; Thoracic Surgery, Video-Assisted ; Thymoma/pathology ; Thymus Neoplasms/pathology
Czasopismo naukowe
Tytuł :
The oncological feasibility and limitations of video-assisted thoracoscopic thymectomy for early-stage thymomas.
Autorzy :
Kimura T; Department of General Thoracic Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
Inoue M
Kadota Y
Shiono H
Shintani Y
Nakagiri T
Funaki S
Sawabata N
Minami M
Okumura M
Pokaż więcej
Źródło :
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery [Eur J Cardiothorac Surg] 2013 Sep; Vol. 44 (3), pp. e214-8. Date of Electronic Publication: 2013 Jun 12.
Typ publikacji :
Journal Article
MeSH Terms :
Thoracic Surgery, Video-Assisted/*methods
Thymectomy/*methods
Thymoma/*surgery
Thymus Neoplasms/*surgery
Aged ; Chi-Square Distribution ; Female ; Humans ; Male ; Middle Aged ; Radiography, Thoracic ; Retrospective Studies ; Sternotomy/adverse effects ; Sternotomy/methods ; Thoracic Surgery, Video-Assisted/adverse effects ; Thymectomy/adverse effects ; Thymoma/diagnostic imaging ; Thymoma/epidemiology ; Thymus Neoplasms/diagnostic imaging ; Thymus Neoplasms/epidemiology ; Tomography, X-Ray Computed
Czasopismo naukowe
Tytuł :
Radiation-induced osteosarcoma 17 years after mediastinal irradiation following surgical removal of thymoma.
Autorzy :
Kadota Y; Department of General Thoracic Surgery, Osaka University Graduate School of Medicine, L-5, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan. />Utsumi T
Inoue M
Sawabata N
Minami M
Okumura M
Pokaż więcej
Źródło :
General thoracic and cardiovascular surgery [Gen Thorac Cardiovasc Surg] 2010 Dec; Vol. 58 (12), pp. 651-3. Date of Electronic Publication: 2010 Dec 18.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Thymectomy*
Bone Neoplasms/*etiology
Neoplasms, Radiation-Induced/*etiology
Osteosarcoma/*etiology
Sternum/*radiation effects
Thymoma/*therapy
Thymus Neoplasms/*therapy
Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Biopsy ; Bone Neoplasms/drug therapy ; Bone Neoplasms/pathology ; Fatal Outcome ; Female ; Humans ; Middle Aged ; Neoplasms, Radiation-Induced/pathology ; Osteosarcoma/drug therapy ; Osteosarcoma/secondary ; Radiotherapy, Adjuvant/adverse effects ; Sternum/pathology ; Thymoma/radiotherapy ; Thymoma/surgery ; Thymus Neoplasms/radiotherapy ; Thymus Neoplasms/surgery ; Time Factors ; Tomography, X-Ray Computed ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Biological implications of thymectomy for myasthenia gravis.
Autorzy :
Okumura M; Department of General Thoracic Surgery, Osaka University Graduate School of Medicine, (L-5), 2-2 Yamada-oka, Suita, Osaka, Japan.
Inoue M
Kadota Y
Hayashi A
Tokunaga T
Kusu T
Sawabata N
Shiono H
Pokaż więcej
Źródło :
Surgery today [Surg Today] 2010; Vol. 40 (2), pp. 102-7. Date of Electronic Publication: 2010 Jan 28.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Thymectomy*
Myasthenia Gravis/*immunology
Myasthenia Gravis/*surgery
Receptors, Nicotinic/*immunology
T-Lymphocytes/*immunology
Thymoma/*immunology
Adult ; Age Factors ; Autoantibodies ; B-Lymphocytes/immunology ; Cyclosporine/therapeutic use ; Humans ; Immunosuppressive Agents/therapeutic use ; Myasthenia Gravis/drug therapy ; Receptor Protein-Tyrosine Kinases ; Receptors, Cholinergic ; Tacrolimus/therapeutic use ; Thymoma/surgery ; Thymus Gland/immunology
Czasopismo naukowe
Tytuł :
Postoperative radiation therapy after complete resection of thymoma has little impact on survival.
Autorzy :
Utsumi T; Department of General Thoracic Surgery, Osaka University Graduate School of Medicine, Suita, Japan. />Shiono H
Kadota Y
Matsumura A
Maeda H
Ohta M
Yoshioka Y
Koizumi M
Inoue T
Okumura M
Pokaż więcej
Źródło :
Cancer [Cancer] 2009 Dec 01; Vol. 115 (23), pp. 5413-20.
Typ publikacji :
Journal Article
MeSH Terms :
Thymoma/*radiotherapy
Thymus Neoplasms/*radiotherapy
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Combined Modality Therapy ; Female ; Humans ; Male ; Middle Aged ; Neoplasm Recurrence, Local ; Postoperative Period ; Radiotherapy, Adjuvant/mortality ; Retrospective Studies ; Survival Rate ; Thymoma/mortality ; Thymoma/surgery ; Thymus Neoplasms/mortality ; Thymus Neoplasms/surgery ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Immunological function of thymoma and pathogenesis of paraneoplastic myasthenia gravis.
Autorzy :
Okumura M; Department of General Thoracic Surgery (L5), Osaka University Graduate School of Medicine, 2-2 Yamada-oka, Suita, Osaka, 565-0871, Japan. />Fujii Y
Shiono H
Inoue M
Minami M
Utsumi T
Kadota Y
Sawa Y
Pokaż więcej
Źródło :
General thoracic and cardiovascular surgery [Gen Thorac Cardiovasc Surg] 2008 Apr; Vol. 56 (4), pp. 143-50. Date of Electronic Publication: 2008 Apr 10.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Myasthenia Gravis/*physiopathology
Paraneoplastic Endocrine Syndromes/*physiopathology
Thymoma/*immunology
Thymus Neoplasms/*immunology
CD4-CD8 Ratio ; Humans ; Myasthenia Gravis/etiology ; Paraneoplastic Endocrine Syndromes/etiology ; T-Lymphocytes/immunology
Czasopismo naukowe
Tytuł :
Clinical and pathological aspects of thymic epithelial tumors.
Autorzy :
Okumura M; Department of General Thoracic Surgery (L5), Osaka University Graduate School of Medicine, 2-2 Yamada-oka, Suita, Osaka, 565-0871, Japan. />Shiono H
Minami M
Inoue M
Utsumi T
Kadota Y
Sawa Y
Pokaż więcej
Źródło :
General thoracic and cardiovascular surgery [Gen Thorac Cardiovasc Surg] 2008 Jan; Vol. 56 (1), pp. 10-6. Date of Electronic Publication: 2008 Jan 22.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Epithelial Cells/*pathology
Thymoma/*pathology
Thymus Neoplasms/*pathology
Gene Expression Regulation, Neoplastic ; Humans ; Myasthenia Gravis/complications ; Risk Factors ; Survival Analysis ; Thymectomy ; Thymoma/classification ; Thymoma/complications ; Thymoma/genetics ; Thymoma/mortality ; Thymoma/surgery ; Thymus Neoplasms/classification ; Thymus Neoplasms/complications ; Thymus Neoplasms/genetics ; Thymus Neoplasms/mortality ; Thymus Neoplasms/surgery ; Tomography, X-Ray Computed ; Treatment Outcome ; World Health Organization
Czasopismo naukowe
Tytuł :
Autoimmunizing mechanisms in thymoma and thymus.
Autorzy :
Willcox N; Neuroscience Group, Weatherall Institute for Molecular Medicine, University of Oxford, England, UK. />Leite MI
Kadota Y
Jones M
Meager A
Subrahmanyam P
Dasgupta B
Morgan BP
Vincent A
Pokaż więcej
Źródło :
Annals of the New York Academy of Sciences [Ann N Y Acad Sci] 2008; Vol. 1132, pp. 163-73.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Autoimmunity/*immunology
Thymoma/*immunology
Thymus Gland/*immunology
Antigen Presentation/immunology ; Humans ; Interferon-gamma/biosynthesis ; Myasthenia Gravis/complications ; Myasthenia Gravis/immunology ; Myasthenia Gravis/metabolism ; Receptors, Cholinergic/immunology ; Receptors, Cholinergic/metabolism ; Thymoma/complications ; Thymoma/metabolism ; Thymoma/pathology ; Thymus Gland/metabolism
Czasopismo naukowe
Tytuł :
Role of positive selection of thymoma-associated T cells in the pathogenesis of myasthenia gravis.
Autorzy :
Inada K; Department of Surgery, Division of General Thoracic Surgery, Osaka University Graduate School of Medicine, Suita-City, Osaka 565-0871, Japan.
Okumura M
Shiono H
Inoue M
Kadota Y
Ohta M
Matsuda H
Pokaż więcej
Źródło :
The Journal of surgical research [J Surg Res] 2005 Jun 01; Vol. 126 (1), pp. 34-40.
Typ publikacji :
Journal Article
MeSH Terms :
Myasthenia Gravis/*etiology
T-Lymphocytes/*immunology
Thymoma/*immunology
Adult ; Aged ; Antigens, CD/analysis ; Antigens, CD1/analysis ; Antigens, Differentiation, T-Lymphocyte/analysis ; Cell Lineage ; Female ; Humans ; Lectins, C-Type ; Male ; Middle Aged ; Myasthenia Gravis/immunology ; Receptors, Antigen, T-Cell, alpha-beta/analysis ; Receptors, Antigen, T-Cell, gamma-delta/analysis
Czasopismo naukowe
Tytuł :
Glucocorticoids induce G1 cell cycle arrest in human neoplastic thymic epithelial cells.
Autorzy :
Funakoshi Y; Division of General Thoracic Surgery, Department of Surgery (E1), Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, 565-0871 Osaka, Japan.
Shiono H
Inoue M
Kadota Y
Ohta M
Matsuda H
Okumura M
Eimoto T
Pokaż więcej
Źródło :
Journal of cancer research and clinical oncology [J Cancer Res Clin Oncol] 2005 May; Vol. 131 (5), pp. 314-22. Date of Electronic Publication: 2005 Feb 10.
Typ publikacji :
Journal Article
MeSH Terms :
G1 Phase/*drug effects
Glucocorticoids/*pharmacology
Glucocorticoids/*therapeutic use
Thymoma/*pathology
Thymoma/*surgery
Thymus Neoplasms/*pathology
Thymus Neoplasms/*surgery
Adult ; Aged ; Apoptosis ; Cell Cycle/drug effects ; Female ; Humans ; In Situ Nick-End Labeling ; Male ; Middle Aged ; Neoplasm Staging ; Thymoma/drug therapy ; Thymus Neoplasms/drug therapy
Czasopismo naukowe
Tytuł :
Three-color flow cytometric study on lymphocytes derived from thymic diseases.
Autorzy :
Okumura M; Department of Surgery (E-1), Graduate School of Medicine, Osaka University, Suita-City, Japan. />Fujii Y
Miyoshi S
Shiono H
Inoue M
Kadota Y
Fukuhara K
Matsuda H
Pokaż więcej
Źródło :
The Journal of surgical research [J Surg Res] 2001 Dec; Vol. 101 (2), pp. 130-7.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Flow Cytometry*
T-Lymphocytes/*immunology
Thymoma/*immunology
Thymus Neoplasms/*immunology
CD3 Complex/analysis ; CD4 Antigens/analysis ; CD8 Antigens/analysis ; Humans ; Hyperplasia ; Thymus Gland/pathology
Czasopismo naukowe
Tytuł :
Clinical and functional significance of WHO classification on human thymic epithelial neoplasms: a study of 146 consecutive tumors.
Autorzy :
Okumura M; Department of Surgery (E-1), Osaka University Graduate School of Medicine, Suita-City, Japan. />Miyoshi S
Fujii Y
Takeuchi Y
Shiono H
Inoue M
Fukuhara K
Kadota Y
Tateyama H
Eimoto T
Matsuda H
Pokaż więcej
Źródło :
The American journal of surgical pathology [Am J Surg Pathol] 2001 Jan; Vol. 25 (1), pp. 103-10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
CD4-CD8 Ratio*
World Health Organization*
Thymoma/*classification
Thymus Neoplasms/*classification
Cell Differentiation ; Child ; Child, Preschool ; Humans ; Infant ; Myasthenia Gravis/complications ; Neoplasm Staging ; T-Lymphocytes/physiology ; Thymoma/immunology ; Thymoma/pathology ; Thymus Gland/pathology ; Thymus Neoplasms/immunology ; Thymus Neoplasms/pathology
Czasopismo naukowe
Tytuł :
Altered T cell development in human thymoma is related to impairment of MHC class II transactivator expression induced by interferon-gamma (IFN-gamma).
Autorzy :
Kadota Y; Division of Organ Transplantation, Biomedical Research Center, Osaka, Japan.
Okumura M
Miyoshi S
Kitagawa-Sakakida S
Inoue M
Shiono H
Maeda Y
Kinoshita T
Shirakura R
Matsuda H
Pokaż więcej
Źródło :
Clinical and experimental immunology [Clin Exp Immunol] 2000 Jul; Vol. 121 (1), pp. 59-68.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Nuclear Proteins*
HLA-DR Antigens/*genetics
Interferon-gamma/*immunology
T-Lymphocytes/*cytology
Thymoma/*immunology
Thymus Neoplasms/*immunology
Trans-Activators/*genetics
Adolescent ; Adult ; Aged ; Epithelial Cells/drug effects ; Epithelial Cells/metabolism ; Gene Expression/drug effects ; HLA-DR Antigens/biosynthesis ; Humans ; Intercellular Adhesion Molecule-1/biosynthesis ; Interferon-gamma/pharmacology ; Middle Aged ; Polymerase Chain Reaction/methods ; RNA, Messenger/analysis ; T-Lymphocytes/drug effects ; T-Lymphocytes/immunology ; Thymoma/blood ; Thymus Gland/cytology ; Thymus Neoplasms/blood ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
Impaired expression of MHC class II molecules in response to interferon-gamma (IFN-gamma) on human thymoma neoplastic epithelial cells.
Autorzy :
Inoue M; First Department of Surgery, Division of Organ Transplantation Biomedical Research Centre, Osaka University Medical School, Osaka, Japan.
Okumura M
Miyoshi S
Shiono H
Fukuhara K
Kadota Y
Shirakura R
Matsuda H
Pokaż więcej
Źródło :
Clinical and experimental immunology [Clin Exp Immunol] 1999 Jul; Vol. 117 (1), pp. 1-7.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genes, MHC Class II*
Antigens, Neoplasm/*biosynthesis
Gene Expression Regulation, Neoplastic/*drug effects
HLA-D Antigens/*biosynthesis
Interferon-gamma/*pharmacology
Thymoma/*pathology
Thymus Neoplasms/*pathology
Adult ; Antigens, Neoplasm/genetics ; Autoimmune Diseases/etiology ; CD3 Complex/analysis ; Cell Lineage ; Epithelial Cells/drug effects ; Epithelial Cells/immunology ; Epithelial Cells/metabolism ; Female ; Flow Cytometry ; Genes, MHC Class I ; HLA Antigens/biosynthesis ; HLA Antigens/genetics ; HLA-D Antigens/genetics ; Humans ; Lymphocyte Count ; Lymphocytosis/etiology ; Lymphocytosis/pathology ; Male ; Middle Aged ; Myasthenia Gravis/etiology ; Recombinant Proteins ; Stromal Cells/drug effects ; T-Lymphocyte Subsets ; Thymoma/complications ; Thymoma/immunology ; Thymus Neoplasms/complications ; Thymus Neoplasms/immunology ; Tumor Cells, Cultured/drug effects
Czasopismo naukowe

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