Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Wyszukujesz frazę ""Kagami K"" wg kryterium: Autor


Wyświetlanie 1-16 z 16
Tytuł:
Utility of ASNS gene methylation evaluated with the HPLC method as a pharmacogenomic biomarker to predict asparaginase sensitivity in BCP-ALL.
Autorzy:
Watanabe A; Department of Pediatrics Environmental Medicine, School of Medicine, University of Yamanashi, Yamanashi, Japan.
Miyake K; Department of Epidemiology and Environmental Medicine, School of Medicine, University of Yamanashi, Yamanashi, Japan.
Yamada Y; Tsukuba Research Institute, Research and Development, Sekisui Medical Co, Ltd, Ibaraki, Japan.
Sunamura EI; Tsukuba Research Institute, Research and Development, Sekisui Medical Co, Ltd, Ibaraki, Japan.
Yotani T; Instrument System Development Center, Research and Development, Sekisui Medical Co, Ltd, Ibaraki, Japan.
Kagami K; Department of Pediatrics Environmental Medicine, School of Medicine, University of Yamanashi, Yamanashi, Japan.
Kasai S; Department of Pediatrics Environmental Medicine, School of Medicine, University of Yamanashi, Yamanashi, Japan.
Tamai M; Department of Pediatrics Environmental Medicine, School of Medicine, University of Yamanashi, Yamanashi, Japan.
Harama D; Department of Pediatrics Environmental Medicine, School of Medicine, University of Yamanashi, Yamanashi, Japan.
Akahane K; Department of Pediatrics Environmental Medicine, School of Medicine, University of Yamanashi, Yamanashi, Japan.
Goi K; Department of Pediatrics Environmental Medicine, School of Medicine, University of Yamanashi, Yamanashi, Japan.
Sakaguchi K; Department of Pediatrics, Hamamatsu University School of Medicine, Shizuoka, Japan.
Goto H; Hematology/Oncology, Kanagawa Children's Medical Center, Kanagawa, Japan.
Kitahara S; R&D Management Department, Research and Development, Sekisui Medical Co, Ltd, Tokyo, Japan.
Inukai T; Department of Pediatrics Environmental Medicine, School of Medicine, University of Yamanashi, Yamanashi, Japan.
Pokaż więcej
Źródło:
Epigenetics [Epigenetics] 2023 Dec; Vol. 18 (1), pp. 2268814. Date of Electronic Publication: 2023 Oct 15.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Aspartate-Ammonia Ligase*/genetics
Aspartate-Ammonia Ligase*/metabolism
Precursor Cell Lymphoblastic Leukemia-Lymphoma*/drug therapy
Precursor Cell Lymphoblastic Leukemia-Lymphoma*/genetics
Humans ; Asparaginase/genetics ; Asparaginase/metabolism ; Asparaginase/therapeutic use ; Asparagine/genetics ; Asparagine/metabolism ; Asparagine/therapeutic use ; Chromatography, High Pressure Liquid ; Pharmacogenetics ; DNA Methylation ; Cell Line, Tumor
Czasopismo naukowe
Tytuł:
Introduction of the T315I gatekeeper mutation of BCR/ABL1 into a Philadelphia chromosome-positive lymphoid leukemia cell line using the CRISPR/Cas9 system.
Autorzy:
Nguyen TTT; Department of Pediatrics, School of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan.
Tamai M; Department of Pediatrics, School of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan.
Harama D; Department of Pediatrics, School of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan.
Kagami K; Department of Pediatrics, School of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan.
Kasai S; Department of Pediatrics, School of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan.
Watanabe A; Department of Pediatrics, School of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan.
Akahane K; Department of Pediatrics, School of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan.
Goi K; Department of Pediatrics, School of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan.
Inukai T; Department of Pediatrics, School of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan. .
Pokaż więcej
Źródło:
International journal of hematology [Int J Hematol] 2022 Oct; Vol. 116 (4), pp. 534-543. Date of Electronic Publication: 2022 May 06.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents*/therapeutic use
Leukemia, Myelogenous, Chronic, BCR-ABL Positive*/drug therapy
Precursor Cell Lymphoblastic Leukemia-Lymphoma*/drug therapy
Precursor Cell Lymphoblastic Leukemia-Lymphoma*/genetics
CRISPR-Associated Protein 9/genetics ; CRISPR-Associated Protein 9/metabolism ; CRISPR-Cas Systems ; Cell Line ; Dasatinib/therapeutic use ; Drug Resistance, Neoplasm/genetics ; Fusion Proteins, bcr-abl ; Humans ; Imatinib Mesylate/pharmacology ; Imatinib Mesylate/therapeutic use ; Mutation ; Nucleotides/therapeutic use ; Oligodeoxyribonucleotides/therapeutic use ; Philadelphia Chromosome ; Poly (ADP-Ribose) Polymerase-1/genetics ; Poly (ADP-Ribose) Polymerase-1/metabolism ; Protein Kinase Inhibitors/pharmacology ; Protein Kinase Inhibitors/therapeutic use ; RNA, Guide, CRISPR-Cas Systems/therapeutic use
Czasopismo naukowe
Tytuł:
Glucocorticoid receptor gene mutations confer glucocorticoid resistance in B-cell precursor acute lymphoblastic leukemia.
Autorzy:
Tamai M; Department of Pediatrics, School of Medicine, University of Yamanashi, Yamanashi, Japan. Electronic address: .
Kasai S; Department of Pediatrics, School of Medicine, University of Yamanashi, Yamanashi, Japan.
Akahane K; Department of Pediatrics, School of Medicine, University of Yamanashi, Yamanashi, Japan.
Thu TN; Department of Pediatrics, School of Medicine, University of Yamanashi, Yamanashi, Japan.
Kagami K; Department of Pediatrics, School of Medicine, University of Yamanashi, Yamanashi, Japan.
Komatsu C; Department of Pediatrics, School of Medicine, University of Yamanashi, Yamanashi, Japan.
Abe M; Department of Pediatrics, School of Medicine, University of Yamanashi, Yamanashi, Japan.
Watanabe A; Department of Pediatrics, School of Medicine, University of Yamanashi, Yamanashi, Japan.
Goi K; Department of Pediatrics, School of Medicine, University of Yamanashi, Yamanashi, Japan.
Miyake K; Department of Health Sciences, School of Medicine, University of Yamanashi, Yamanashi, Japan.
Inaba T; Department of Molecular Oncology, Research Institute of Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan.
Takita J; Department of Pediatrics, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Goto H; Hematology/Oncology and Regenerative Medicine, Kanagawa Children's Medical Center, Kanagawa, Japan.
Minegishi M; Japanese Red Cross Fukushima Blood Center, Fukushima, Japan.
Iwamoto S; Department of Pediatrics, Mie University Graduate School of Medicine, Tsu, Japan.
Sugita K; Department of Pediatrics, School of Medicine, University of Yamanashi, Yamanashi, Japan.
Inukai T; Department of Pediatrics, School of Medicine, University of Yamanashi, Yamanashi, Japan.
Pokaż więcej
Źródło:
The Journal of steroid biochemistry and molecular biology [J Steroid Biochem Mol Biol] 2022 Apr; Vol. 218, pp. 106068. Date of Electronic Publication: 2022 Feb 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Precursor Cell Lymphoblastic Leukemia-Lymphoma*/genetics
Receptors, Glucocorticoid*/deficiency
Receptors, Glucocorticoid*/genetics
Receptors, Glucocorticoid*/metabolism
Glucocorticoids/pharmacology ; Glucocorticoids/therapeutic use ; Humans ; Metabolism, Inborn Errors ; Mutation ; Recurrence
SCR Disease Name:
Glucocorticoid Receptor Deficiency
Czasopismo naukowe
Tytuł:
Epigenetic Modification of Death Receptor Genes for TRAIL and TRAIL Resistance in Childhood B-Cell Precursor Acute Lymphoblastic Leukemia.
Autorzy:
Watanabe A; Department of Pediatrics, Faculty of Medicine, University of Yamanashi, Yamanashi 409-3898, Japan.
Miyake K; Department of Health Sciences, University of Yamanashi, Yamanashi 409-3898, Japan.
Akahane K; Department of Pediatrics, Faculty of Medicine, University of Yamanashi, Yamanashi 409-3898, Japan.
Goi K; Department of Pediatrics, Faculty of Medicine, University of Yamanashi, Yamanashi 409-3898, Japan.
Kagami K; Department of Pediatrics, Faculty of Medicine, University of Yamanashi, Yamanashi 409-3898, Japan.
Yagita H; Department of Immunology, School of Medicine, Juntendo University, Tokyo 113-8421, Japan.
Inukai T; Department of Pediatrics, Faculty of Medicine, University of Yamanashi, Yamanashi 409-3898, Japan.
Pokaż więcej
Źródło:
Genes [Genes (Basel)] 2021 Jun 05; Vol. 12 (6). Date of Electronic Publication: 2021 Jun 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
DNA Methylation*
Drug Resistance, Neoplasm*
Epigenesis, Genetic*
Precursor Cell Lymphoblastic Leukemia-Lymphoma/*genetics
Receptors, TNF-Related Apoptosis-Inducing Ligand/*genetics
Cell Line, Tumor ; CpG Islands ; Humans ; Promoter Regions, Genetic ; Receptors, TNF-Related Apoptosis-Inducing Ligand/metabolism ; TNF-Related Apoptosis-Inducing Ligand/metabolism ; TNF-Related Apoptosis-Inducing Ligand/toxicity
Czasopismo naukowe
Tytuł:
Inherited genetic variants associated with glucocorticoid sensitivity in leukaemia cells.
Autorzy:
Shinohara T; Department of Pediatrics, School of Medicine, University of Yamanashi, Chuo, Japan.
Urayama KY; Department of Social Medicine, National Center for Child Health and Development, Tokyo, Japan.; Graduate School of Public Health, St Luke's International University, Tokyo, Japan.
Watanabe A; Department of Pediatrics, School of Medicine, University of Yamanashi, Chuo, Japan.
Akahane K; Department of Pediatrics, School of Medicine, University of Yamanashi, Chuo, Japan.
Goi K; Department of Pediatrics, School of Medicine, University of Yamanashi, Chuo, Japan.
Huang M; Department of Pediatrics, School of Medicine, University of Yamanashi, Chuo, Japan.
Kagami K; Department of Pediatrics, School of Medicine, University of Yamanashi, Chuo, Japan.
Abe M; Department of Pediatrics, School of Medicine, University of Yamanashi, Chuo, Japan.
Sugita K; Department of Pediatrics, School of Medicine, University of Yamanashi, Chuo, Japan.
Okada Y; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Osaka, Japan.
Goto H; Hematology/Oncology and Regenerative Medicine, Kanagawa Children's Medical Center, Yokohama, Japan.
Minegishi M; Tohoku Block Center, Japanese Red Cross Society, Sendai, Japan.
Iwamoto S; Department of Pediatrics, Mie University Graduate School of Medicine, Tsu, Japan.
Inukai T; Department of Pediatrics, School of Medicine, University of Yamanashi, Chuo, Japan.
Pokaż więcej
Źródło:
Journal of cellular and molecular medicine [J Cell Mol Med] 2020 Nov; Vol. 24 (22), pp. 12920-12932. Date of Electronic Publication: 2020 Oct 01.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression Regulation, Leukemic*
Genetic Variation*
Glucocorticoids/*pharmacology
Precursor Cell Lymphoblastic Leukemia-Lymphoma/*drug therapy
Precursor Cell Lymphoblastic Leukemia-Lymphoma/*genetics
Cell Line, Tumor ; Dexamethasone/pharmacology ; Drug Screening Assays, Antitumor ; Gene Expression Profiling ; Genotype ; Humans ; Inhibitory Concentration 50 ; Japan ; Pharmacogenetics ; Polymorphism, Single Nucleotide ; Prednisolone/pharmacology ; Receptors, Glucocorticoid/genetics
Czasopismo naukowe
Tytuł:
Resistance of t(17;19)-acute lymphoblastic leukemia cell lines to multiagents in induction therapy.
Autorzy:
Watanabe A; Department of Pediatrics, School of Medicine, University of Yamanashi, Chuo, Japan.
Inukai T; Department of Pediatrics, School of Medicine, University of Yamanashi, Chuo, Japan.
Kagami K; Department of Pediatrics, School of Medicine, University of Yamanashi, Chuo, Japan.
Abe M; Department of Pediatrics, School of Medicine, University of Yamanashi, Chuo, Japan.
Takagi M; Department of Pediatrics and Developmental Biology, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Fukushima T; Department of Child Health, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Fukushima H; Department of Child Health, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Nanmoku T; Department of Clinical Laboratory, University of Tsukuba Hospital, Tsukuba, Japan.
Terui K; Department of Pediatrics, Hirosaki University School of Medicine, Hirosaki, Japan.
Ito T; Department of Pediatrics, Hirosaki University School of Medicine, Hirosaki, Japan.
Toki T; Department of Pediatrics, Hirosaki University School of Medicine, Hirosaki, Japan.
Ito E; Department of Pediatrics, Hirosaki University School of Medicine, Hirosaki, Japan.
Fujimura J; Department of Pediatrics and Adolescent Medicine, Juntendo University School of Medicine, Tokyo, Japan.
Goto H; Hematology/Oncology & Regenerative Medicine, Kanagawa Children's Medical Center.
Endo M; Department of Pediatrics, Iwate Medical University School of Medicine, Morioka, Japan.
Look T; Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
Kamps M; Department of Pathology, University of California School of Medicine, La Jolla, California.
Minegishi M; Tohoku Block Center, Japanese Red Cross Society, Sendai, Japan.
Takita J; Department of Pediatrics, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Inaba T; Department of Molecular Oncology, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan.
Takahashi H; Tokyo Children's Cancer Study Group, Tokyo, Japan.
Ohara A; Tokyo Children's Cancer Study Group, Tokyo, Japan.
Harama D; Department of Pediatrics, School of Medicine, University of Yamanashi, Chuo, Japan.
Shinohara T; Department of Pediatrics, School of Medicine, University of Yamanashi, Chuo, Japan.
Somazu S; Department of Pediatrics, School of Medicine, University of Yamanashi, Chuo, Japan.
Oshiro H; Department of Pediatrics, School of Medicine, University of Yamanashi, Chuo, Japan.
Akahane K; Department of Pediatrics, School of Medicine, University of Yamanashi, Chuo, Japan.
Goi K; Department of Pediatrics, School of Medicine, University of Yamanashi, Chuo, Japan.
Sugita K; Department of Pediatrics, School of Medicine, University of Yamanashi, Chuo, Japan.
Pokaż więcej
Źródło:
Cancer medicine [Cancer Med] 2019 Sep; Vol. 8 (11), pp. 5274-5288. Date of Electronic Publication: 2019 Jul 15.
Typ publikacji:
Journal Article
MeSH Terms:
Chromosomes, Human, Pair 17*
Chromosomes, Human, Pair 19*
Translocation, Genetic*
Drug Resistance, Neoplasm/*genetics
Precursor Cell Lymphoblastic Leukemia-Lymphoma/*genetics
ATP Binding Cassette Transporter, Subfamily B, Member 1/genetics ; ATP Binding Cassette Transporter, Subfamily B, Member 1/metabolism ; Alleles ; Animals ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/therapeutic use ; Cell Line ; Disease Models, Animal ; Dose-Response Relationship, Drug ; Female ; Gene Frequency ; Genotype ; Humans ; Immunophenotyping ; Mice ; Neoplasm, Residual/diagnosis ; Neoplasm, Residual/genetics ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/diagnosis ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/drug therapy
Czasopismo naukowe
Tytuł:
Chemosensitivity is differentially regulated by the SDF-1/CXCR4 and SDF-1/CXCR7 axes in acute lymphoblastic leukemia with MLL gene rearrangements.
Autorzy:
Ando N; Department of Pediatrics, Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan.
Furuichi Y; Department of Pediatrics, Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan.
Kasai S; Department of Pediatrics, Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan.
Tamai M; Department of Pediatrics, Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan.
Harama D; Department of Pediatrics, Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan.
Kagami K; Department of Pediatrics, Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan.
Abe M; Department of Pediatrics, Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan.
Goi K; Department of Pediatrics, Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan.
Inukai T; Department of Pediatrics, Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan.
Sugita K; Department of Pediatrics, Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan. Electronic address: .
Pokaż więcej
Źródło:
Leukemia research [Leuk Res] 2018 Dec; Vol. 75, pp. 36-44. Date of Electronic Publication: 2018 Nov 03.
Typ publikacji:
Journal Article
MeSH Terms:
Drug Resistance, Neoplasm/*genetics
Histone-Lysine N-Methyltransferase/*genetics
Myeloid-Lymphoid Leukemia Protein/*genetics
Precursor Cell Lymphoblastic Leukemia-Lymphoma/*genetics
Antineoplastic Agents/pharmacology ; Apoptosis/drug effects ; Cell Line, Tumor ; Chemokine CXCL12/metabolism ; Cytarabine/pharmacology ; Gene Rearrangement ; Humans ; Receptors, CXCR/metabolism ; Receptors, CXCR4/metabolism
Czasopismo naukowe
Tytuł:
TGFβ1 synergizes with FLT3 ligand to induce chemoresistant quiescence in acute lymphoblastic leukemia with MLL gene rearrangements.
Autorzy:
Tamai M; Department of Pediatrics, Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan.
Furuichi Y; Department of Pediatrics, Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan.
Kasai S; Department of Pediatrics, Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan.
Ando N; Department of Pediatrics, Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan.
Harama D; Department of Pediatrics, Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan.
Goi K; Department of Pediatrics, Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan.
Inukai T; Department of Pediatrics, Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan.
Kagami K; Department of Pediatrics, Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan.
Abe M; Department of Pediatrics, Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan.
Ichikawa H; Division of Genetics, National Cancer Center Research Institute, Tokyo, Japan.
Sugita K; Department of Pediatrics, Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan. Electronic address: .
Pokaż więcej
Źródło:
Leukemia research [Leuk Res] 2017 Oct; Vol. 61, pp. 68-76. Date of Electronic Publication: 2017 Sep 14.
Typ publikacji:
Journal Article
MeSH Terms:
Drug Resistance, Neoplasm/*physiology
Membrane Proteins/*metabolism
Precursor Cell Lymphoblastic Leukemia-Lymphoma/*metabolism
Transforming Growth Factor beta1/*metabolism
Blotting, Western ; Cell Line, Tumor ; Flow Cytometry ; Gene Expression Regulation, Neoplastic/physiology ; Gene Rearrangement ; Histone-Lysine N-Methyltransferase/genetics ; Humans ; Myeloid-Lymphoid Leukemia Protein/genetics ; Oligonucleotide Array Sequence Analysis ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/genetics ; Real-Time Polymerase Chain Reaction ; fms-Like Tyrosine Kinase 3/metabolism
Czasopismo naukowe
Tytuł:
Inflammatory mediator ultra-low-molecular-weight hyaluronan triggers necrosis of B-precursor leukemia cells with high surface CD44 expression.
Autorzy:
Kasai S; Departments of Pediatrics, Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan.
Furuichi Y; Departments of Pediatrics, Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan.
Ando N; Departments of Pediatrics, Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan.
Kagami K; Departments of Pediatrics, Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan.
Abe M; Departments of Pediatrics, Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan.
Nakane T; Departments of Pediatrics, Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan.
Goi K; Departments of Pediatrics, Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan.
Inukai T; Departments of Pediatrics, Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan.
Saitoh S; Departments of Anatomy and Molecular Histology, Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan.
Ohno S; Departments of Anatomy and Molecular Histology, Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan.
Okazaki S; Division of Gene Regulation, Institute for Advanced Medical Research, School of Medicine, Keio University, Tokyo, Japan.
Nagano O; Division of Gene Regulation, Institute for Advanced Medical Research, School of Medicine, Keio University, Tokyo, Japan.
Saya H; Division of Gene Regulation, Institute for Advanced Medical Research, School of Medicine, Keio University, Tokyo, Japan.
Sugita K; Departments of Pediatrics, Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan.
Pokaż więcej
Źródło:
Cell death & disease [Cell Death Dis] 2017 Jun 01; Vol. 8 (6), pp. e2857. Date of Electronic Publication: 2017 Jun 01.
Typ publikacji:
Journal Article
MeSH Terms:
Hyaluronan Receptors/*genetics
Hyaluronic Acid/*pharmacology
Necrosis/*genetics
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma/*genetics
Precursor Cell Lymphoblastic Leukemia-Lymphoma/*genetics
Biological Transport/drug effects ; Cell Line, Tumor ; Cell Survival/drug effects ; Child ; Child, Preschool ; Female ; Gene Expression ; HMGB1 Protein/metabolism ; Humans ; Hyaluronan Receptors/metabolism ; Hyaluronic Acid/antagonists & inhibitors ; Imidazoles/pharmacology ; Indoles/pharmacology ; Infant ; Male ; Molecular Weight ; Necrosis/chemically induced ; Necrosis/metabolism ; Necrosis/pathology ; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma/metabolism ; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma/pathology ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/metabolism ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/pathology ; Precursor Cells, B-Lymphoid/drug effects ; Precursor Cells, B-Lymphoid/metabolism ; Precursor Cells, B-Lymphoid/pathology ; Reactive Oxygen Species/agonists ; Reactive Oxygen Species/metabolism ; Thymidine/metabolism
Czasopismo naukowe
Tytuł:
Oncogenic fusion E2A-HLF sensitizes t(17;19)-positive acute lymphoblastic leukemia to TRAIL-mediated apoptosis by upregulating the expression of death receptors.
Autorzy:
Zhang X; Department of Pediatrics, School of Medicine, University of Yamanashi, Yamanashi, Japan.
Inukai T
Hirose K
Akahane K
Kuroda I
Honna-Oshiro H
Kagami K
Goi K
Nakamura K
Kobayashi M
Endo M
Yagita H
Kurosawa H
Thomas Look A
Honda H
Inaba T
Nakazawa S
Sugita K
Pokaż więcej
Źródło:
Leukemia [Leukemia] 2012 Dec; Vol. 26 (12), pp. 2483-93. Date of Electronic Publication: 2012 May 30.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis/*drug effects
Chromosomes, Human, Pair 17/*genetics
Chromosomes, Human, Pair 19/*genetics
DNA-Binding Proteins/*genetics
Oncogene Proteins, Fusion/*genetics
Precursor Cell Lymphoblastic Leukemia-Lymphoma/*genetics
Receptors, TNF-Related Apoptosis-Inducing Ligand/*genetics
TNF-Related Apoptosis-Inducing Ligand/*pharmacology
Transcription Factors/*genetics
Translocation, Genetic/*genetics
Blotting, Western ; Cell Proliferation ; DNA-Binding Proteins/metabolism ; Electrophoretic Mobility Shift Assay ; Humans ; Luciferases/metabolism ; Oncogene Proteins, Fusion/metabolism ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/metabolism ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/pathology ; Promoter Regions, Genetic/genetics ; RNA, Messenger/genetics ; Real-Time Polymerase Chain Reaction ; Receptors, TNF-Related Apoptosis-Inducing Ligand/metabolism ; Reverse Transcriptase Polymerase Chain Reaction ; Transcription Factors/metabolism ; Transcriptional Activation ; Tumor Cells, Cultured ; Up-Regulation
Czasopismo naukowe
Tytuł:
Induction of impaired membrane phospholipid asymmetry in mature erythrocytes after chemotherapy.
Autorzy:
Zhang X; Department of Pediatrics, School of Medicine, University of Yamanashi, Japan.
Inukai T
Hirose K
Akahane K
Nemoto A
Takahashi K
Sato H
Kagami K
Goi K
Sugita K
Nakazawa S
Pokaż więcej
Źródło:
International journal of hematology [Int J Hematol] 2005 Aug; Vol. 82 (2), pp. 132-6.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antimetabolites, Antineoplastic/*administration & dosage
Cytarabine/*administration & dosage
Erythrocyte Membrane/*metabolism
Phospholipids/*metabolism
Precursor Cell Lymphoblastic Leukemia-Lymphoma/*drug therapy
Annexin A5/metabolism ; Bone Marrow/metabolism ; Bone Marrow/pathology ; Cellular Senescence/drug effects ; Erythrocyte Membrane/pathology ; Erythropoiesis/drug effects ; Humans ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/blood ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/pathology
Czasopismo naukowe
Tytuł:
Abnormalities of the p16INK4a gene in childhood B-precursor acute lymphoblastic leukemia without nonrandom translocations: analysis of seven matched pairs of primary leukemia and corresponding cell line.
Autorzy:
Nakamura M
Sugita K
Inukai T
Goi K
Miyamoto N
Kagami K
Okazaki-Koyama T
Mori T
Saito M
Nakazawa S
Pokaż więcej
Źródło:
Leukemia [Leukemia] 2001 Jul; Vol. 15 (7), pp. 1136-9.
Typ publikacji:
Letter
MeSH Terms:
Genes, p16*
Translocation, Genetic*
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma/*genetics
Precursor Cell Lymphoblastic Leukemia-Lymphoma/*genetics
Adolescent ; Child ; Female ; Humans ; Tumor Cells, Cultured
Opinia redakcyjna
Tytuł:
p16/MTS1/INK4A gene is frequently inactivated by hypermethylation in childhood acute lymphoblastic leukemia with 11q23 translocation.
Autorzy:
Nakamura M; Department of Pediatrics, Yamanashi Medical University, Japan.
Sugita K
Inukai T
Goi K
Iijima K
Tezuka T
Kojika S
Shiraishi K
Miyamoto N
Karakida N
Kagami K
O-Koyama T
Mori T
Nakazawa S
Pokaż więcej
Źródło:
Leukemia [Leukemia] 1999 Jun; Vol. 13 (6), pp. 884-90.
Typ publikacji:
Journal Article
MeSH Terms:
Chromosomes, Human, Pair 11*
DNA Methylation*
Cyclin-Dependent Kinase Inhibitor p16/*genetics
Precursor Cell Lymphoblastic Leukemia-Lymphoma/*genetics
Blotting, Southern ; Blotting, Western ; Child ; Child, Preschool ; CpG Islands/genetics ; Cyclin-Dependent Kinase Inhibitor p16/biosynthesis ; Gene Expression Regulation, Neoplastic ; Humans ; Translocation, Genetic ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł:
The KOR-SA3544 antigen predominantly expressed on the surface of Philadelphia chromosome-positive acute lymphoblastic leukemia cells is nonspecific cross-reacting antigen-50/90 (CD66c) and invariably expressed in cytoplasm of human leukemia cells.
Autorzy:
Sugita K; Department of Pediatrics, Yamanashi Medical University, Japan.
Mori T
Yokota S
Kuroki M
Koyama TO
Inukai T
Iijima K
Goi K
Tezuka T
Kojika S
Shiraishi K
Nakamura M
Miyamoto N
Karakida N
Kagami K
Nakazawa S
Pokaż więcej
Źródło:
Leukemia [Leukemia] 1999 May; Vol. 13 (5), pp. 779-85.
Typ publikacji:
Journal Article
MeSH Terms:
Antigens, Neoplasm*
Cell Adhesion Molecules*
Philadelphia Chromosome*
Cytoplasm/*chemistry
Membrane Glycoproteins/*analysis
Precursor Cell Lymphoblastic Leukemia-Lymphoma/*immunology
Antibodies, Monoclonal/immunology ; Antigens, CD ; Blotting, Western ; Flow Cytometry ; Fluorescent Antibody Technique ; GPI-Linked Proteins ; Granulocytes/chemistry ; Humans ; Immunohistochemistry ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/genetics
Czasopismo naukowe
    Wyświetlanie 1-16 z 16

    Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies