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Wyszukujesz frazę ""Kaminski, Michael M"" wg kryterium: Autor


Tytuł :
Deep learning is widely applicable to phenotyping embryonic development and disease.
Autorzy :
Naert T; Institute of Anatomy, University of Zurich, Zurich 8057, Switzerland; Swiss National Centre of Competence in Research (NCCR) Kidney Control of Homeostasis (Kidney.CH), Zurich 8057, Switzerland.
Çiçek Ö; Department of Computer Science, Albert-Ludwigs-University, Freiburg 79100, Germany.
Ogar P; Institute of Anatomy, University of Zurich, Zurich 8057, Switzerland; Swiss National Centre of Competence in Research (NCCR) Kidney Control of Homeostasis (Kidney.CH), Zurich 8057, Switzerland.
Bürgi M; Institute of Anatomy, University of Zurich, Zurich 8057, Switzerland; Swiss National Centre of Competence in Research (NCCR) Kidney Control of Homeostasis (Kidney.CH), Zurich 8057, Switzerland.
Shaidani NI; National Xenopus Resource and Eugene Bell Center for Regenerative Biology and Tissue Engineering, Marine Biological Laboratory, Woods Hole, MA 02543, USA.
Kaminski MM; Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin 10115, Germany.; Department of Nephrology and Medical Intensive Care, Charité Universitätsmedizin Berlin, Berlin 10117, Germany.
Xu Y; Department of Psychiatry and Behavioral Sciences, UCSF Weill Institute for Neurosciences, University of California, San Francisco, CA 94158, USA.
Grand K; Institute of Anatomy, University of Zurich, Zurich 8057, Switzerland; Swiss National Centre of Competence in Research (NCCR) Kidney Control of Homeostasis (Kidney.CH), Zurich 8057, Switzerland.
Vujanovic M; Institute of Anatomy, University of Zurich, Zurich 8057, Switzerland; Swiss National Centre of Competence in Research (NCCR) Kidney Control of Homeostasis (Kidney.CH), Zurich 8057, Switzerland.
Prata D; Institute of Anatomy, University of Zurich, Zurich 8057, Switzerland; Swiss National Centre of Competence in Research (NCCR) Kidney Control of Homeostasis (Kidney.CH), Zurich 8057, Switzerland.
Hildebrandt F; Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115,USA.
Brox T; Department of Computer Science, Albert-Ludwigs-University, Freiburg 79100, Germany.
Ronneberger O; Department of Computer Science, Albert-Ludwigs-University, Freiburg 79100, Germany.; BIOSS Centre for Biological Signalling Studies, Albert-Ludwigs-University, Freiburg, Germany.; DeepMind, London WC2H 8AG , UK.
Voigt FF; Laboratory of Neural Circuit Dynamics, Brain Research Institute, University of Zurich, Zurich 8057, Switzerland; Neuroscience Center Zurich, Zurich 8057, Switzerland.
Helmchen F; Laboratory of Neural Circuit Dynamics, Brain Research Institute, University of Zurich, Zurich 8057, Switzerland; Neuroscience Center Zurich, Zurich 8057, Switzerland.
Loffing J; Institute of Anatomy, University of Zurich, Zurich 8057, Switzerland; Swiss National Centre of Competence in Research (NCCR) Kidney Control of Homeostasis (Kidney.CH), Zurich 8057, Switzerland.
Horb ME; National Xenopus Resource and Eugene Bell Center for Regenerative Biology and Tissue Engineering, Marine Biological Laboratory, Woods Hole, MA 02543, USA.
Willsey HR; Department of Psychiatry and Behavioral Sciences, UCSF Weill Institute for Neurosciences, University of California, San Francisco, CA 94158, USA.
Lienkamp SS; Institute of Anatomy, University of Zurich, Zurich 8057, Switzerland; Swiss National Centre of Competence in Research (NCCR) Kidney Control of Homeostasis (Kidney.CH), Zurich 8057, Switzerland.
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Źródło :
Development (Cambridge, England) [Development] 2021 Nov 01; Vol. 148 (21). Date of Electronic Publication: 2021 Nov 05.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
CRISPR-based diagnostics.
Autorzy :
Kaminski MM; Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine, Berlin, Germany.; Department of Nephrology and Medical Intensive Care, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Abudayyeh OO; McGovern Institute for Brain Research at MIT, Cambridge, MA, USA.; Massachusetts Consortium for Pathogen Readiness, Boston, MA, USA.
Gootenberg JS; McGovern Institute for Brain Research at MIT, Cambridge, MA, USA.; Massachusetts Consortium for Pathogen Readiness, Boston, MA, USA.
Zhang F; McGovern Institute for Brain Research at MIT, Cambridge, MA, USA.; Massachusetts Consortium for Pathogen Readiness, Boston, MA, USA.; Howard Hughes Medical Institute, Cambridge, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Brain and Cognitive Sciences, MIT, Cambridge, MA, USA.; Department of Biological Engineering, MIT, Cambridge, MA, USA.
Collins JJ; Broad Institute of MIT and Harvard, Cambridge, MA, USA. .; Department of Biological Engineering, MIT, Cambridge, MA, USA. .; Institute for Medical Engineering and Science, MIT, Cambridge, MA, USA. .; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA. .
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Źródło :
Nature biomedical engineering [Nat Biomed Eng] 2021 Jul; Vol. 5 (7), pp. 643-656. Date of Electronic Publication: 2021 Jul 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
CRISPR-Cas Systems/*genetics
Communicable Diseases/*diagnosis
Nucleic Acid Amplification Techniques/*methods
Nucleic Acids/*analysis
Communicable Diseases/microbiology ; Communicable Diseases/virology ; Genetic Diseases, Inborn/diagnosis ; Humans ; Nucleic Acid Amplification Techniques/economics ; Nucleic Acids/metabolism ; Point-of-Care Systems ; Polymorphism, Single Nucleotide ; Sequence Analysis, DNA
Czasopismo naukowe
Tytuł :
Mutations in transcription factor CP2-like 1 may cause a novel syndrome with distal renal tubulopathy in humans.
Autorzy :
Klämbt V; Division of Nephrology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Werth M; Division of Nephrology, Columbia University, New York, NY, USA.
Onuchic-Whitford AC; Division of Nephrology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Renal Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Getwan M; Department of Medicine, Renal Division, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Kitzler TM; Division of Nephrology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Buerger F; Division of Nephrology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Mao Y; Division of Nephrology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Deutsch K; Division of Nephrology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Mann N; Division of Nephrology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Majmundar AJ; Division of Nephrology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Kaminski MM; Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany.; Department of Nephrology and Medical Intensive Care, Charité - Universitaetsmedizin Berlin, Germany.
Shen T; Division of Nephrology, Columbia University, New York, NY, USA.
Schmidt-Ott KM; Department of Nephrology and Medical Intensive Care, Charité - Universitaetsmedizin Berlin, Germany.
Shalaby M; Pediatric Nephrology Center of Excellence and Pediatric Department, Faculty of Medicine, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia.
El Desoky S; Pediatric Nephrology Center of Excellence and Pediatric Department, Faculty of Medicine, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia.
Kari JA; Pediatric Nephrology Center of Excellence and Pediatric Department, Faculty of Medicine, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia.
Shril S; Division of Nephrology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Lienkamp SS; Department of Medicine, Renal Division, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Institute of Anatomy, University of Zurich, Zurich, Switzerland.
Barasch J; Division of Nephrology, Columbia University, New York, NY, USA.
Hildebrandt F; Division of Nephrology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
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Źródło :
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association [Nephrol Dial Transplant] 2021 Jan 25; Vol. 36 (2), pp. 237-246.
Typ publikacji :
Case Reports; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Epithelial-Mesenchymal Transition*
Mutation*
Kidney Diseases/*etiology
Repressor Proteins/*genetics
Animals ; Child ; DNA-Binding Proteins/genetics ; DNA-Binding Proteins/metabolism ; Female ; HEK293 Cells ; Humans ; Kidney Diseases/metabolism ; Kidney Diseases/pathology ; Mice ; Mice, Knockout ; Rats ; Repressor Proteins/metabolism ; Single-Cell Analysis ; Transcription Factors/genetics ; Transcription Factors/metabolism ; Whole Exome Sequencing
Czasopismo naukowe
Tytuł :
Impact of Diabetic Stress Conditions on Renal Cell Metabolome.
Autorzy :
Lagies S; Center for Biological Systems Analysis (ZBSA), Albert-Ludwigs-University Freiburg, Habsburgerstr. 49, 79104 Freiburg, Germany.; Spemann Graduate School of Biology and Medicine (SGBM), University of Freiburg, 79104 Freiburg, Germany.; Faculty of Biology, University of Freiburg, 79104 Freiburg, Germany.
Pichler R; Department of Medicine, Renal Division, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.
Bork T; Department of Medicine, Renal Division, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.
Kaminski MM; Department of Medicine, Renal Division, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.
Troendle K; Laboratory for MEMS Applications, IMTEK-Department of Microsystems Engineering, University of Freiburg, 79110 Freiburg, Germany.
Zimmermann S; Laboratory for MEMS Applications, IMTEK-Department of Microsystems Engineering, University of Freiburg, 79110 Freiburg, Germany.
Huber TB; III. Department of Medicine, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Walz G; Department of Medicine, Renal Division, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.; BIOSS Centre of Biological Signalling Studies, University of Freiburg, 79104 Freiburg, Germany.
Lienkamp SS; Department of Medicine, Renal Division, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.; Institute of Anatomy, University of Zurich, 8057 Zurich, Switzerland.
Kammerer B; Center for Biological Systems Analysis (ZBSA), Albert-Ludwigs-University Freiburg, Habsburgerstr. 49, 79104 Freiburg, Germany. .; BIOSS Centre of Biological Signalling Studies, University of Freiburg, 79104 Freiburg, Germany. .
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Źródło :
Cells [Cells] 2019 Sep 24; Vol. 8 (10). Date of Electronic Publication: 2019 Sep 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Metabolome*/drug effects
Diabetic Nephropathies/*metabolism
Diabetic Nephropathies/*pathology
Podocytes/*metabolism
Podocytes/*pathology
Albumins/pharmacology ; Animals ; Cells, Cultured ; Diabetes Mellitus/metabolism ; Diabetes Mellitus/pathology ; Embryo, Mammalian ; Glucose/pharmacology ; Humans ; Kidney/drug effects ; Kidney/metabolism ; Kidney/pathology ; Mice ; Mice, Transgenic ; Oxidative Stress/drug effects ; Oxidative Stress/physiology ; Podocytes/drug effects
Czasopismo naukowe
Tytuł :
Fabrication of Kidney Proximal Tubule Grafts Using Biofunctionalized Electrospun Polymer Scaffolds.
Autorzy :
Jansen K; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Universiteitsweg 99,, 3584, CG Utrecht, The Netherlands.
Castilho M; Department of Orthopaedics, University Medical Center Utrecht, Utrecht University, P.O. Box 85500,, 3508, GA Utrecht, The Netherlands.; Regenerative Medicine Center Utrecht, Uppsalalaan 8,, 3584, CT Utrecht, The Netherlands.
Aarts S; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Universiteitsweg 99,, 3584, CG Utrecht, The Netherlands.; Department of Orthopaedics, University Medical Center Utrecht, Utrecht University, P.O. Box 85500,, 3508, GA Utrecht, The Netherlands.
Kaminski MM; University Medical Center Freiburg, Zentrale Klinische Forschung, Breisacher Straße 66,, 79106, Freiburg im Breisgau, Germany.
Lienkamp SS; University Medical Center Freiburg, Zentrale Klinische Forschung, Breisacher Straße 66,, 79106, Freiburg im Breisgau, Germany.
Pichler R; University Medical Center Freiburg, Zentrale Klinische Forschung, Breisacher Straße 66,, 79106, Freiburg im Breisgau, Germany.
Malda J; Department of Orthopaedics, University Medical Center Utrecht, Utrecht University, P.O. Box 85500,, 3508, GA Utrecht, The Netherlands.; Regenerative Medicine Center Utrecht, Uppsalalaan 8,, 3584, CT Utrecht, The Netherlands.; Department of Equine Sciences, Room G05228, University Medical Center Utrecht, Utrecht University, Heidelberglaan 100,, 3584, CX Utrecht, The Netherlands.
Vermonden T; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Universiteitsweg 99,, 3584, CG Utrecht, The Netherlands.; Division of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Universiteitsweg 99,, 3584, CG Utrecht, The Netherlands.; Regenerative Medicine Center Utrecht, Uppsalalaan 8,, 3584, CT Utrecht, The Netherlands.
Jansen J; Department of Pathology and Pediatric Nephrology, RIMLS, RIHS, Radboud University Medical Center, P.O. Box 9101, 6500, HB Nijmegen, The Netherlands.
Masereeuw R; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Universiteitsweg 99,, 3584, CG Utrecht, The Netherlands.; Regenerative Medicine Center Utrecht, Uppsalalaan 8,, 3584, CT Utrecht, The Netherlands.
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Źródło :
Macromolecular bioscience [Macromol Biosci] 2019 Feb; Vol. 19 (2), pp. e1800412. Date of Electronic Publication: 2018 Dec 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Tissue Scaffolds*
Epithelial Cells/*cytology
Kidney Tubules, Proximal/*cytology
Kidney Tubules, Proximal/*surgery
Tissue Engineering/*methods
Transplants/*growth & development
Biocompatible Materials/therapeutic use ; Caproates/chemistry ; Cell Proliferation ; Cells, Cultured ; Humans ; Kidney Failure, Chronic/surgery ; Lactones/chemistry ; Polymers
Czasopismo naukowe
Tytuł :
Metabolic characterization of directly reprogrammed renal tubular epithelial cells (iRECs).
Autorzy :
Lagies S; Center for Biosystems Analysis (ZBSA), Albert-Ludwigs-University Freiburg, Habsburgerstr. 49, 79104, Freiburg, Germany.; Spemann Graduate School of Biology and Medicine (SGBM), University of Freiburg, Albertstr. 19a, 79104, Freiburg, Germany.; Faculty of Biology, University of Freiburg, Schänzlestr. 1, 79104, Freiburg, Germany.
Pichler R; Department of Medicine, Renal Division, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106, Freiburg, Germany.
Kaminski MM; Department of Medicine, Renal Division, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106, Freiburg, Germany.
Schlimpert M; Center for Biosystems Analysis (ZBSA), Albert-Ludwigs-University Freiburg, Habsburgerstr. 49, 79104, Freiburg, Germany.; Spemann Graduate School of Biology and Medicine (SGBM), University of Freiburg, Albertstr. 19a, 79104, Freiburg, Germany.; Faculty of Biology, University of Freiburg, Schänzlestr. 1, 79104, Freiburg, Germany.
Walz G; Department of Medicine, Renal Division, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106, Freiburg, Germany.; BIOSS Centre of Biological Signalling Studies, University of Freiburg, Schänzlestr. 18, 79104, Freiburg, Germany.
Lienkamp SS; Department of Medicine, Renal Division, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106, Freiburg, Germany. .; BIOSS Centre of Biological Signalling Studies, University of Freiburg, Schänzlestr. 18, 79104, Freiburg, Germany. .
Kammerer B; Center for Biosystems Analysis (ZBSA), Albert-Ludwigs-University Freiburg, Habsburgerstr. 49, 79104, Freiburg, Germany. .; BIOSS Centre of Biological Signalling Studies, University of Freiburg, Schänzlestr. 18, 79104, Freiburg, Germany. .
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Źródło :
Scientific reports [Sci Rep] 2018 Mar 01; Vol. 8 (1), pp. 3878. Date of Electronic Publication: 2018 Mar 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Epithelial Cells/*metabolism
Kidney Tubules/*metabolism
Animals ; Cell Differentiation/physiology ; Cellular Reprogramming/physiology ; Cluster Analysis ; Fibroblasts/metabolism ; Gas Chromatography-Mass Spectrometry/methods ; Metabolome/genetics ; Metabolomics ; Mice ; Mice, Inbred C57BL ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł :
A Dominant Mutation in Nuclear Receptor Interacting Protein 1 Causes Urinary Tract Malformations via Dysregulation of Retinoic Acid Signaling.
Autorzy :
Vivante A; Departments of Medicine and.; Talpiot Medical Leadership Program, Sheba Medical Center, Tel-Hashomer, Israel.
Mann N; Departments of Medicine and.
Yonath H; Department of Internal Medicine A and Genetics Institute, Sheba Medical Center and Sackler Faculty of Medicine Tel Aviv University, Tel Aviv, Israel.
Weiss AC; Institut für Molekularbiologie, Medizinische Hochschule Hannover, Hannover, Germany.
Getwan M; Department of Medicine, Renal Division, University Medical Center, Faculty of Medicine, and.
Kaminski MM; Department of Medicine, Renal Division, University Medical Center, Faculty of Medicine, and.
Bohnenpoll T; Institut für Molekularbiologie, Medizinische Hochschule Hannover, Hannover, Germany.
Teyssier C; Institut de Recherche en Cancérologie de Montpellier (IRCM), Montpellier, France; Institut National de la Santé et de la Recherche Médicale (INSERM), Montpellier, France; Université Montpellier, Montpellier, France; Institut régional du Cancer de Montpellier, Montpellier, France.
Chen J; Departments of Medicine and.
Shril S; Departments of Medicine and.
van der Ven AT; Departments of Medicine and.
Ityel H; Departments of Medicine and.
Schmidt JM; Departments of Medicine and.
Widmeier E; Departments of Medicine and.; Department of Medicine, Renal Division, University Medical Center, Faculty of Medicine, and.
Bauer SB; Urology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts.
Sanna-Cherchi S; Division of Nephrology, Columbia University, New York, New York.
Gharavi AG; Division of Nephrology, Columbia University, New York, New York.
Lu W; Renal Section, Department of Medicine, Boston University Medical Center, Boston, Massachusetts.
Magen D; Pediatric Nephrology Institute, Rambam Health Care Campus, and Technion-Israel Institute of Technology, Haifa, Israel.
Shukrun R; Department of Pediatrics, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel-Hashomer, Israel and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Lifton RP; Department of Human Genetics, Yale University School of Medicine, New Haven, Connecticut.; Howard Hughes Medical Institute, Chevy Chase, Maryland.
Tasic V; Department of Pediatric Nephrology, Medical Faculty Skopje, University Children's Hospital, Skopje, Macedonia; and.
Stanescu HC; Centre for Nephrology, University College London, London, United Kingdom.
Cavaillès V; Institut de Recherche en Cancérologie de Montpellier (IRCM), Montpellier, France; Institut National de la Santé et de la Recherche Médicale (INSERM), Montpellier, France; Université Montpellier, Montpellier, France; Institut régional du Cancer de Montpellier, Montpellier, France.
Kleta R; Centre for Nephrology, University College London, London, United Kingdom.
Anikster Y; Department of Pediatrics, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel-Hashomer, Israel and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Dekel B; Department of Pediatrics, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel-Hashomer, Israel and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Kispert A; Institut für Molekularbiologie, Medizinische Hochschule Hannover, Hannover, Germany.
Lienkamp SS; Department of Medicine, Renal Division, University Medical Center, Faculty of Medicine, and.; Center for Biological Signaling Studies (BIOSS), Albert Ludwig University, Freiburg, Germany.
Hildebrandt F; Departments of Medicine and .
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Źródło :
Journal of the American Society of Nephrology : JASN [J Am Soc Nephrol] 2017 Aug; Vol. 28 (8), pp. 2364-2376. Date of Electronic Publication: 2017 Apr 05.
Typ publikacji :
Journal Article
MeSH Terms :
Mutation*
Adaptor Proteins, Signal Transducing/*genetics
Nuclear Proteins/*genetics
Signal Transduction/*genetics
Tretinoin/*physiology
Urinary Tract/*abnormalities
Animals ; Mice ; Nuclear Receptor Interacting Protein 1
Czasopismo naukowe
Tytuł :
Engineering kidney cells: reprogramming and directed differentiation to renal tissues.
Autorzy :
Kaminski MM; Department of Medicine, Renal Division, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Strasse 55, 79106, Freiburg, Germany.
Tosic J; Institute of Experimental and Clinical Pharmacology and Toxicology, Faculty of Medicine, University of Freiburg, Albertstrasse 25, 79104, Freiburg, Germany.; Spemann Graduate School of Biology and Medicine (SGBM), University of Freiburg, Albertstrasse 19a, 79104, Freiburg, Germany.; Faculty of Biology, University of Freiburg, Schänzlestrasse 1, 79104, Freiburg, Germany.
Pichler R; Department of Medicine, Renal Division, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Strasse 55, 79106, Freiburg, Germany.
Arnold SJ; Institute of Experimental and Clinical Pharmacology and Toxicology, Faculty of Medicine, University of Freiburg, Albertstrasse 25, 79104, Freiburg, Germany.; BIOSS Centre of Biological Signalling Studies, University of Freiburg, Schänzlestrasse 18, 79104, Freiburg, Germany.
Lienkamp SS; Department of Medicine, Renal Division, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Strasse 55, 79106, Freiburg, Germany. .; BIOSS Centre of Biological Signalling Studies, University of Freiburg, Schänzlestrasse 18, 79104, Freiburg, Germany. .
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Źródło :
Cell and tissue research [Cell Tissue Res] 2017 Jul; Vol. 369 (1), pp. 185-197. Date of Electronic Publication: 2017 May 30.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Cellular Reprogramming*
Gene Expression Regulation*
Kidney*/cytology
Kidney*/metabolism
Transcription Factors*/genetics
Transcription Factors*/metabolism
Cellular Reprogramming Techniques/*methods
Tissue Engineering/*methods
Animals ; Humans
Czasopismo naukowe
Tytuł :
Direct reprogramming of fibroblasts into renal tubular epithelial cells by defined transcription factors.
Autorzy :
Kaminski MM; Department of Medicine, Renal Division, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Straße 55, 79106 Freiburg, Germany.
Tosic J; Department of Medicine, Renal Division, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Straße 55, 79106 Freiburg, Germany.; Institute of Experimental and Clinical Pharmacology and Toxicology, University of Freiburg, Faculty of Medicine, Albertstraße 25, 79104 Freiburg, Germany.; Spemann Graduate School of Biology and Medicine (SGBM), University of Freiburg, Albertstraße 19a, 79104 Freiburg, Germany.; Faculty of Biology, University of Freiburg, Schänzlestraße 1, 79104 Freiburg, Germany.
Kresbach C; Department of Medicine, Renal Division, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Straße 55, 79106 Freiburg, Germany.
Engel H; Department of Medicine, Renal Division, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Straße 55, 79106 Freiburg, Germany.
Klockenbusch J; Department of Medicine, Renal Division, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Straße 55, 79106 Freiburg, Germany.
Müller AL; Department of Medicine, Renal Division, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Straße 55, 79106 Freiburg, Germany.
Pichler R; Department of Medicine, Renal Division, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Straße 55, 79106 Freiburg, Germany.
Grahammer F; Department of Medicine, Renal Division, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Straße 55, 79106 Freiburg, Germany.
Kretz O; Department of Medicine, Renal Division, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Straße 55, 79106 Freiburg, Germany.; Department of Neuroanatomy, University of Freiburg, Albertstraße 17, 79104 Freiburg, Germany.
Huber TB; Department of Medicine, Renal Division, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Straße 55, 79106 Freiburg, Germany.; BIOSS Centre of Biological Signalling Studies, University of Freiburg, Schänzlestraße 18, 79104 Freiburg, Germany.
Walz G; Department of Medicine, Renal Division, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Straße 55, 79106 Freiburg, Germany.; BIOSS Centre of Biological Signalling Studies, University of Freiburg, Schänzlestraße 18, 79104 Freiburg, Germany.
Arnold SJ; Department of Medicine, Renal Division, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Straße 55, 79106 Freiburg, Germany.; Institute of Experimental and Clinical Pharmacology and Toxicology, University of Freiburg, Faculty of Medicine, Albertstraße 25, 79104 Freiburg, Germany.; BIOSS Centre of Biological Signalling Studies, University of Freiburg, Schänzlestraße 18, 79104 Freiburg, Germany.
Lienkamp SS; Department of Medicine, Renal Division, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Straße 55, 79106 Freiburg, Germany.; BIOSS Centre of Biological Signalling Studies, University of Freiburg, Schänzlestraße 18, 79104 Freiburg, Germany.
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Źródło :
Nature cell biology [Nat Cell Biol] 2016 Dec; Vol. 18 (12), pp. 1269-1280. Date of Electronic Publication: 2016 Nov 07.
Typ publikacji :
Journal Article
MeSH Terms :
Cellular Reprogramming*
Epithelial Cells/*cytology
Fibroblasts/*cytology
Kidney Tubules/*cytology
Transcription Factors/*metabolism
Animals ; Cell Aggregation ; Cell Lineage ; Cell Proliferation ; Cell Shape ; Cells, Cultured ; Cluster Analysis ; Embryo, Mammalian/cytology ; Epithelial Cells/ultrastructure ; Fluorescent Antibody Technique ; Gene Expression Profiling ; Humans ; Mice ; Nephrons/cytology ; Nephrons/metabolism ; Organoids/cytology ; Xenopus
Czasopismo naukowe
Tytuł :
Mutations in TBX18 Cause Dominant Urinary Tract Malformations via Transcriptional Dysregulation of Ureter Development.
Autorzy :
Vivante A; Department of Medicine, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA; Talpiot Medical Leadership Program, Sheba Medical Center, Tel-Hashomer 52621, Israel.
Kleppa MJ; Institut für Molekularbiologie, Medizinische Hochschule Hannover 30625, Germany.
Schulz J; Department of Medicine, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Kohl S; Department of Medicine, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Sharma A; Pediatric Nephrology Unit and Endocrine Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.
Chen J; Department of Medicine, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Shril S; Department of Medicine, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Hwang DY; Department of Medicine, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA; Division of Nephrology, Department of Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Weiss AC; Institut für Molekularbiologie, Medizinische Hochschule Hannover 30625, Germany.
Kaminski MM; Department of Medicine, Renal Division, University of Freiburg Medical Center, 79106 Freiburg, Germany.
Shukrun R; Department of Medicine, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Kemper MJ; Department of Pediatrics, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Lehnhardt A; Department of Pediatrics, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Beetz R; Center for Pediatric and Adolescent Medicine, University Medical Clinic, 55131 Mainz, Germany.
Sanna-Cherchi S; Department of Medicine, Columbia University, New York, NY 10023, USA.
Verbitsky M; Department of Medicine, Columbia University, New York, NY 10023, USA.
Gharavi AG; Department of Medicine, Columbia University, New York, NY 10023, USA.
Stuart HM; Institute of Human Development, Faculty of Medical and Human Sciences, University of Manchester, Manchester Academic Health Science Centre and the Royal Manchester Children's and St Mary's Hospitals, Manchester M13 9WL, UK.
Feather SA; Leeds Teaching Hospitals NHS Trust, Leeds LS1 3EX, UK.
Goodship JA; Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne NE1 3BZ, UK.
Goodship TH; Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne NE1 3BZ, UK.
Woolf AS; Institute of Human Development, Faculty of Medical and Human Sciences, University of Manchester, Manchester Academic Health Science Centre and the Royal Manchester Children's and St Mary's Hospitals, Manchester M13 9WL, UK.
Westra SJ; Pediatric Radiology Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.
Doody DP; Department of Pediatric Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.
Bauer SB; Department of Urology, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Lee RS; Department of Urology, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Adam RM; Department of Urology, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Lu W; Renal Section, Department of Medicine, Boston University Medical Center, Boston, MA 02118, USA.
Reutter HM; Department of Neonatology, Children's Hospital, University of Bonn, 53127 Bonn, Germany.
Kehinde EO; Division of Urology, Department of Surgery, Kuwait University, 13110 Safat, Kuwait.
Mancini EJ; Division of Structural Biology, The Wellcome Trust Centre for Human Genetics, University of Oxford, Headington, Oxford OX3 7BN, UK; School of Life Sciences, University of Sussex, Brighton BN1 9QD, UK.
Lifton RP; Department of Human Genetics, Yale University School of Medicine, New Haven, CT 06510, USA; Howard Hughes Medical Institute.
Tasic V; Medical School Skopje, University Children's Hospital, 1000 Skopje, Macedonia.
Lienkamp SS; Department of Medicine, Renal Division, University of Freiburg Medical Center, 79106 Freiburg, Germany; Center for Biological Signaling Studies (BIOSS), 79104 Freiburg, Germany.
Jüppner H; Pediatric Nephrology Unit and Endocrine Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.
Kispert A; Institut für Molekularbiologie, Medizinische Hochschule Hannover 30625, Germany.
Hildebrandt F; Department of Medicine, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA; Howard Hughes Medical Institute. Electronic address: .
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Źródło :
American journal of human genetics [Am J Hum Genet] 2015 Aug 06; Vol. 97 (2), pp. 291-301. Date of Electronic Publication: 2015 Jul 30.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Gene Expression Regulation, Developmental/*genetics
Genes, Dominant/*genetics
Muscle, Smooth/*embryology
Mutation/*genetics
T-Box Domain Proteins/*genetics
Ureter/*embryology
Urinary Tract/*abnormalities
Base Sequence ; Electrophoretic Mobility Shift Assay ; Exome/genetics ; HEK293 Cells ; Humans ; Immunohistochemistry ; Immunoprecipitation ; Microscopy, Fluorescence ; Molecular Sequence Data ; Pedigree ; Sequence Analysis, DNA
Czasopismo naukowe

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