Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Wyszukujesz frazę ""Karsdal, Morten"" wg kryterium: Autor


Tytuł:
LPA 1 antagonist BMS-986020 changes collagen dynamics and exerts antifibrotic effects in vitro and in patients with idiopathic pulmonary fibrosis.
Autorzy:
Decato BE; Research & Early Development, Bristol Myers Squibb, 3401 Princeton Pike, Princeton, NJ, 08648, USA.
Leeming DJ; Nordic Bioscience, Herlev Hovedgade 205-207, 2730 Herlev, Denmark.
Sand JMB; Nordic Bioscience, Herlev Hovedgade 205-207, 2730 Herlev, Denmark.
Fischer A; Research & Early Development, Bristol Myers Squibb, 3401 Princeton Pike, Princeton, NJ, 08648, USA.
Du S; Research & Early Development, Bristol Myers Squibb, 3401 Princeton Pike, Princeton, NJ, 08648, USA.
Palmer SM; Duke University Medical Center, 2085 Msrb2 2 Genome Ct., Durham, NC, 27710, USA.
Karsdal M; Nordic Bioscience, Herlev Hovedgade 205-207, 2730 Herlev, Denmark.
Luo Y; Research & Early Development, Bristol Myers Squibb, 3401 Princeton Pike, Princeton, NJ, 08648, USA.
Minnich A; Research & Early Development, Bristol Myers Squibb, 3401 Princeton Pike, Princeton, NJ, 08648, USA. .
Pokaż więcej
Źródło:
Respiratory research [Respir Res] 2022 Mar 18; Vol. 23 (1), pp. 61. Date of Electronic Publication: 2022 Mar 18.
Typ publikacji:
Clinical Trial, Phase II; Journal Article; Randomized Controlled Trial
MeSH Terms:
Collagen/*drug effects
Idiopathic Pulmonary Fibrosis/*drug therapy
Receptors, Lysophosphatidic Acid/*antagonists & inhibitors
Respiratory System Agents/*administration & dosage
Adult ; Aged ; Aged, 80 and over ; Biomarkers/blood ; Collagen/metabolism ; Epitopes/blood ; Female ; Humans ; Idiopathic Pulmonary Fibrosis/pathology ; In Vitro Techniques ; Male ; Middle Aged ; Models, Biological ; Vital Capacity/drug effects
Czasopismo naukowe
Tytuł:
Serological assessment of collagen fragments and tumor fibrosis may guide immune checkpoint inhibitor therapy.
Autorzy:
Jensen C; Biomarkers & Research, Nordic Bioscience, 2730, Herlev, Denmark. .
Nissen NI; Biomarkers & Research, Nordic Bioscience, 2730, Herlev, Denmark.
Von Arenstorff CS; Biomarkers & Research, Nordic Bioscience, 2730, Herlev, Denmark.
Karsdal MA; Biomarkers & Research, Nordic Bioscience, 2730, Herlev, Denmark.
Willumsen N; Biomarkers & Research, Nordic Bioscience, 2730, Herlev, Denmark.
Pokaż więcej
Źródło:
Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2021 Oct 16; Vol. 40 (1), pp. 326. Date of Electronic Publication: 2021 Oct 16.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Collagen/*metabolism
Fibrosis/*metabolism
Immune Checkpoint Inhibitors/*therapeutic use
Humans ; Immune Checkpoint Inhibitors/pharmacology
Czasopismo naukowe
Tytuł:
Progressive alcohol-related liver fibrosis is characterised by imbalanced collagen formation and degradation.
Autorzy:
Thiele M; Fibrosis, Fatty Liver and Steatohepatitis Research Centre Odense (FLASH), Department of Gastroenterology and Hepatology, Odense University Hospital, Odense, Denmark.; Department of Clinical Research, Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark.
Johansen S; Fibrosis, Fatty Liver and Steatohepatitis Research Centre Odense (FLASH), Department of Gastroenterology and Hepatology, Odense University Hospital, Odense, Denmark.
Gudmann NS; Nordic Bioscience A/S, Herlev, Denmark.
Madsen B; Fibrosis, Fatty Liver and Steatohepatitis Research Centre Odense (FLASH), Department of Gastroenterology and Hepatology, Odense University Hospital, Odense, Denmark.
Kjaergaard M; Fibrosis, Fatty Liver and Steatohepatitis Research Centre Odense (FLASH), Department of Gastroenterology and Hepatology, Odense University Hospital, Odense, Denmark.
Nielsen MJ; Nordic Bioscience A/S, Herlev, Denmark.
Leeming DJ; Nordic Bioscience A/S, Herlev, Denmark.
Jacobsen S; Fibrosis, Fatty Liver and Steatohepatitis Research Centre Odense (FLASH), Department of Gastroenterology and Hepatology, Odense University Hospital, Odense, Denmark.
Bendtsen F; Gastro Unit, Medical Section, Hvidovre University Hospital, Hvidovre, Denmark.; Department of Clinical Medicine, Faculty of Health Sciences, University of Copenhagen, Hvidovre, Denmark.
Møller S; Department of Clinical Medicine, Faculty of Health Sciences, University of Copenhagen, Hvidovre, Denmark.; Department of Clinical Physiology and Nuclear Medicine, Centre for Functional and Diagnostic Imaging and Research, Hvidovre Hospital, Hvidovre, Denmark.
Detlefsen S; Department of Clinical Research, Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark.; Department of Pathology, Odense University Hospital, Odense, Denmark.
Karsdal M; Nordic Bioscience A/S, Herlev, Denmark.; Department of Molecular Medicine, Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark.
Krag A; Fibrosis, Fatty Liver and Steatohepatitis Research Centre Odense (FLASH), Department of Gastroenterology and Hepatology, Odense University Hospital, Odense, Denmark.; Department of Clinical Research, Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark.
Pokaż więcej
Corporate Authors:
GALAXY Consortium
Źródło:
Alimentary pharmacology & therapeutics [Aliment Pharmacol Ther] 2021 Oct; Vol. 54 (8), pp. 1070-1080. Date of Electronic Publication: 2021 Aug 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Collagen*
Liver Cirrhosis*/etiology
Biomarkers ; Extracellular Matrix ; Female ; Fibrosis ; Humans ; Liver Cirrhosis, Alcoholic ; Male ; Middle Aged
Czasopismo naukowe
Tytuł:
Correlation between serological biomarkers of extracellular matrix turnover and lung fibrosis and pulmonary artery hypertension in patients with systemic sclerosis.
Autorzy:
Kubo S; The First Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health Japan, Kitakyushu, Japan.
Siebuhr AS; Nordic Bioscience, Biomarkers and Research, Herlev, Denmark.
Bay-Jensen AC; Nordic Bioscience, Biomarkers and Research, Herlev, Denmark.
Juhl P; Nordic Bioscience, Biomarkers and Research, Herlev, Denmark.
Karsdal MA; Nordic Bioscience, Biomarkers and Research, Herlev, Denmark.
Satoh Y; The First Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health Japan, Kitakyushu, Japan.
Todoroki Y; The First Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health Japan, Kitakyushu, Japan.
Nakano K; The First Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health Japan, Kitakyushu, Japan.
Nakayamada S; The First Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health Japan, Kitakyushu, Japan.
Tanaka Y; The First Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health Japan, Kitakyushu, Japan.
Pokaż więcej
Źródło:
International journal of rheumatic diseases [Int J Rheum Dis] 2020 Apr; Vol. 23 (4), pp. 532-539. Date of Electronic Publication: 2020 Feb 05.
Typ publikacji:
Journal Article
MeSH Terms:
Collagen/*blood
Peptide Fragments/*blood
Pulmonary Arterial Hypertension/*blood
Pulmonary Fibrosis/*blood
Scleroderma, Systemic/*blood
Adult ; Aged ; Biomarkers/blood ; Case-Control Studies ; Female ; Humans ; Male ; Middle Aged ; Proteolysis ; Pulmonary Arterial Hypertension/diagnosis ; Pulmonary Arterial Hypertension/etiology ; Pulmonary Fibrosis/diagnosis ; Pulmonary Fibrosis/etiology ; Scleroderma, Systemic/complications ; Scleroderma, Systemic/diagnosis
Czasopismo naukowe
Tytuł:
Collagen fragments quantified in serum as measures of desmoplasia associate with survival outcome in patients with advanced pancreatic cancer.
Autorzy:
Willumsen N; Biomarkers & Research, Nordic Bioscience, Herlev, Denmark. .
Ali SM; Division of Hematology/Oncology, Penn State Health Milton S Hershey Medical Center, Hershey, PA, USA.; Lebanon VA Medical Center, Lebanon, PA, USA.
Leitzel K; Division of Hematology/Oncology, Penn State Health Milton S Hershey Medical Center, Hershey, PA, USA.
Drabick JJ; Division of Hematology/Oncology, Penn State Health Milton S Hershey Medical Center, Hershey, PA, USA.
Yee N; Division of Hematology/Oncology, Penn State Health Milton S Hershey Medical Center, Hershey, PA, USA.
Polimera HV; Division of Hematology/Oncology, Penn State Health Milton S Hershey Medical Center, Hershey, PA, USA.
Nagabhairu V; Pinnacle Health System, University of Pittsburgh Medical Center, Harrisburg, PA, USA.
Krecko L; Division of Hematology/Oncology, Penn State Health Milton S Hershey Medical Center, Hershey, PA, USA.
Ali A; Division of Hematology/Oncology, Penn State Health Milton S Hershey Medical Center, Hershey, PA, USA.
Maddukuri A; Division of Hematology/Oncology, Penn State Health Milton S Hershey Medical Center, Hershey, PA, USA.
Moku P; Division of Hematology/Oncology, Penn State Health Milton S Hershey Medical Center, Hershey, PA, USA.
Ali A; Division of Hematology/Oncology, Penn State Health Milton S Hershey Medical Center, Hershey, PA, USA.
Poulose J; Division of Hematology/Oncology, Penn State Health Milton S Hershey Medical Center, Hershey, PA, USA.
Menon H; Division of Hematology/Oncology, Penn State Health Milton S Hershey Medical Center, Hershey, PA, USA.
Pancholy N; Division of Hematology/Oncology, Penn State Health Milton S Hershey Medical Center, Hershey, PA, USA.
Costa L; Oncology division, Hospital de Santa Maria, Lisboa, Portugal.; Clinical Translational Oncology Research Unit, Institute of Molecular Medicine, Lisboa, Portugal.
Karsdal MA; Biomarkers & Research, Nordic Bioscience, Herlev, Denmark.
Lipton A; Division of Hematology/Oncology, Penn State Health Milton S Hershey Medical Center, Hershey, PA, USA.
Pokaż więcej
Źródło:
Scientific reports [Sci Rep] 2019 Dec 24; Vol. 9 (1), pp. 19761. Date of Electronic Publication: 2019 Dec 24.
Typ publikacji:
Clinical Trial, Phase III; Journal Article; Multicenter Study; Randomized Controlled Trial
MeSH Terms:
Carcinoma, Pancreatic Ductal*/blood
Carcinoma, Pancreatic Ductal*/mortality
Pancreatic Neoplasms*/blood
Pancreatic Neoplasms*/mortality
CA-19-9 Antigen/*blood
Collagen/*blood
Neoplasm Proteins/*blood
Disease-Free Survival ; Double-Blind Method ; Female ; Humans ; Male ; Middle Aged ; Neoplasm Staging ; Survival Rate
Czasopismo naukowe
Tytuł:
Collagen turnover profiles in chronic kidney disease.
Autorzy:
Rasmussen DGK; Nordic Bioscience, Herlev, Denmark. .; Department of Cardiovascular and Renal Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark. .
Boesby L; Department of Medicine, University Hospital Roskilde, Roskilde, Denmark.; Department of Nephrology, Herlev Hospital, Herlev, Denmark.
Nielsen SH; Nordic Bioscience, Herlev, Denmark.; Department of Biotechnology and Biomedicine, Technical University of Denmark, Kgs, Lyngby, Denmark.
Tepel M; Department of Cardiovascular and Renal Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark.; Department of Nephrology, Odense University Hospital, Odense, Denmark.
Birot S; Nordic Bioscience, Herlev, Denmark.
Karsdal MA; Nordic Bioscience, Herlev, Denmark.
Kamper AL; Department of Nephrology, Rigshospitalet, Copenhagen, Denmark.
Genovese F; Nordic Bioscience, Herlev, Denmark.
Pokaż więcej
Źródło:
Scientific reports [Sci Rep] 2019 Nov 05; Vol. 9 (1), pp. 16062. Date of Electronic Publication: 2019 Nov 05.
Typ publikacji:
Clinical Trial; Journal Article; Observational Study; Research Support, Non-U.S. Gov't
MeSH Terms:
Collagen/*blood
Peptides/*blood
Renal Insufficiency, Chronic/*blood
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Biomarkers/blood ; Cross-Sectional Studies ; Extracellular Matrix/metabolism ; Female ; Humans ; Male ; Middle Aged
Czasopismo naukowe
Tytuł:
Biomarkers of collagen synthesis predict progression in the PROFILE idiopathic pulmonary fibrosis cohort.
Autorzy:
Organ LA; Division of Respiratory Medicine, University of Nottingham, Nottingham, UK.
Duggan AR; Fibrosis Discovery Performance Unit, GlaxoSmithKline R&D, GlaxoSmithKline Medicines Research Centre, Gunnels Wood Road, Stevenage, SG1 2NY, UK.
Oballa E; Fibrosis Discovery Performance Unit, GlaxoSmithKline R&D, GlaxoSmithKline Medicines Research Centre, Gunnels Wood Road, Stevenage, SG1 2NY, UK.
Taggart SC; Fibrosis Discovery Performance Unit, GlaxoSmithKline R&D, GlaxoSmithKline Medicines Research Centre, Gunnels Wood Road, Stevenage, SG1 2NY, UK.
Simpson JK; Fibrosis Discovery Performance Unit, GlaxoSmithKline R&D, GlaxoSmithKline Medicines Research Centre, Gunnels Wood Road, Stevenage, SG1 2NY, UK.
Kang'ombe AR; Fibrosis Discovery Performance Unit, GlaxoSmithKline R&D, GlaxoSmithKline Medicines Research Centre, Gunnels Wood Road, Stevenage, SG1 2NY, UK.
Braybrooke R; Division of Respiratory Medicine, University of Nottingham, Nottingham, UK.
Molyneaux PL; NIHR Respiratory Clinical Research Facility, Royal Brompton Hospital, London, UK.; National Heart and Lung Institute, Imperial College, Sir Alexander Fleming Building, London, SW7 2AZ, UK.
North B; Fibrosis Discovery Performance Unit, GlaxoSmithKline R&D, GlaxoSmithKline Medicines Research Centre, Gunnels Wood Road, Stevenage, SG1 2NY, UK.
Karkera Y; Fibrosis Discovery Performance Unit, GlaxoSmithKline R&D, GlaxoSmithKline Medicines Research Centre, Gunnels Wood Road, Stevenage, SG1 2NY, UK.
Leeming DJ; Nordic Bioscience A/S, Biomarkers and Research, Herlev Hovedgade 205-207, DK-2730, Herlev, Denmark.
Karsdal MA; Nordic Bioscience A/S, Biomarkers and Research, Herlev Hovedgade 205-207, DK-2730, Herlev, Denmark.
Nanthakumar CB; Fibrosis Discovery Performance Unit, GlaxoSmithKline R&D, GlaxoSmithKline Medicines Research Centre, Gunnels Wood Road, Stevenage, SG1 2NY, UK.
Fahy WA; Fibrosis Discovery Performance Unit, GlaxoSmithKline R&D, GlaxoSmithKline Medicines Research Centre, Gunnels Wood Road, Stevenage, SG1 2NY, UK.
Marshall RP; Fibrosis Discovery Performance Unit, GlaxoSmithKline R&D, GlaxoSmithKline Medicines Research Centre, Gunnels Wood Road, Stevenage, SG1 2NY, UK.
Jenkins RG; Division of Respiratory Medicine, University of Nottingham, Nottingham, UK. .; Respiratory Research Unit, Nottingham University Hospitals NHS Trust, Nottingham, NG5 1PB, United Kingdom. .
Maher TM; NIHR Respiratory Clinical Research Facility, Royal Brompton Hospital, London, UK. .; National Heart and Lung Institute, Imperial College, Sir Alexander Fleming Building, London, SW7 2AZ, UK. .
Pokaż więcej
Źródło:
Respiratory research [Respir Res] 2019 Jul 12; Vol. 20 (1), pp. 148. Date of Electronic Publication: 2019 Jul 12.
Typ publikacji:
Journal Article; Multicenter Study; Observational Study; Pragmatic Clinical Trial
MeSH Terms:
Disease Progression*
Collagen/*biosynthesis
Collagen/*blood
Idiopathic Pulmonary Fibrosis/*blood
Idiopathic Pulmonary Fibrosis/*diagnosis
Aged ; Aged, 80 and over ; Biomarkers/blood ; Cohort Studies ; Humans ; Longitudinal Studies ; Middle Aged ; Predictive Value of Tests ; Prospective Studies ; Protein Biosynthesis/physiology
Czasopismo naukowe
Tytuł:
Serum biomarkers of collagen turnover as potential diagnostic tools in diffuse systemic sclerosis: A cross-sectional study.
Autorzy:
Juhl P; Biomarkers and Research, Nordic Bioscience, Herlev, Denmark.; Department of Biomedical Sciences, Copenhagen University, Copenhagen, Denmark.
Bay-Jensen AC; Biomarkers and Research, Nordic Bioscience, Herlev, Denmark.
Karsdal M; Biomarkers and Research, Nordic Bioscience, Herlev, Denmark.
Siebuhr AS; Biomarkers and Research, Nordic Bioscience, Herlev, Denmark.
Franchimont N; Clinical Development, Biogen, Cambridge, Massachusetts, United States of America.
Chavez J; Clinical Development, Biogen, Cambridge, Massachusetts, United States of America.
Pokaż więcej
Źródło:
PloS one [PLoS One] 2018 Dec 03; Vol. 13 (12), pp. e0207324. Date of Electronic Publication: 2018 Dec 03 (Print Publication: 2018).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Collagen/*metabolism
Scleroderma, Diffuse/*blood
Scleroderma, Diffuse/*metabolism
Asymptomatic Diseases ; Biomarkers/blood ; Cross-Sectional Studies ; Female ; Humans ; Male ; Middle Aged ; Pilot Projects ; Scleroderma, Diffuse/diagnosis
Czasopismo naukowe
Tytuł:
Serum type XVI collagen is associated with colorectal cancer and ulcerative colitis indicating a pathological role in gastrointestinal disorders.
Autorzy:
Jensen C; Biomarkers & Research, Nordic Bioscience, Herlev, Denmark.; Biotech Research & Innovation Centre (BRIC), University of Copenhagen, Copenhagen, Denmark.
Nielsen SH; Biomarkers & Research, Nordic Bioscience, Herlev, Denmark.; Department of Biotechnology and Biomedicine, Technical University of Denmark, Lyngby, Denmark.
Mortensen JH; Biomarkers & Research, Nordic Bioscience, Herlev, Denmark.
Kjeldsen J; Department of Medical Gastroenterology, Odense University Hospital, Odense, Denmark.
Klinge LG; Department of Medical Gastroenterology, Odense University Hospital, Odense, Denmark.
Krag A; Department of Medical Gastroenterology, Odense University Hospital, Odense, Denmark.
Harling H; Digestive Disease Center, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.
Jørgensen LN; Digestive Disease Center, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.
Karsdal MA; Biomarkers & Research, Nordic Bioscience, Herlev, Denmark.
Willumsen N; Biomarkers & Research, Nordic Bioscience, Herlev, Denmark.
Pokaż więcej
Źródło:
Cancer medicine [Cancer Med] 2018 Sep; Vol. 7 (9), pp. 4619-4626. Date of Electronic Publication: 2018 Jul 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Biomarkers/*blood
Colitis, Ulcerative/*blood
Colitis, Ulcerative/*pathology
Collagen/*blood
Colorectal Neoplasms/*blood
Colorectal Neoplasms/*pathology
Adult ; Aged ; Aged, 80 and over ; Amino Acid Sequence ; Case-Control Studies ; Colitis, Ulcerative/drug therapy ; Colitis, Ulcerative/etiology ; Colorectal Neoplasms/etiology ; Colorectal Neoplasms/therapy ; Enzyme-Linked Immunosorbent Assay ; Extracellular Matrix ; Female ; Humans ; Male ; Middle Aged ; Models, Biological ; Peptides/blood ; Peptides/chemistry ; ROC Curve ; Young Adult
Czasopismo naukowe
Tytuł:
Age-related collagen turnover of the interstitial matrix and basement membrane: Implications of age- and sex-dependent remodeling of the extracellular matrix.
Autorzy:
Kehlet SN; Nordic Bioscience A/S, Herlev, Denmark.; DTU Bioengineering, Department of Biotechnology and Biomedicine, Technical University of Denmark, Kgs. Lyngby, Denmark.
Willumsen N; Nordic Bioscience A/S, Herlev, Denmark.
Armbrecht G; Center for Muscle and Bone Research, Department of Radiology, Campus Benjamin Franklin, CHARITE - University Medicine Berlin, Berlin, Germany.
Dietzel R; Center for Muscle and Bone Research, Department of Radiology, Campus Benjamin Franklin, CHARITE - University Medicine Berlin, Berlin, Germany.
Brix S; DTU Bioengineering, Department of Biotechnology and Biomedicine, Technical University of Denmark, Kgs. Lyngby, Denmark.
Henriksen K; Nordic Bioscience A/S, Herlev, Denmark.
Karsdal MA; Nordic Bioscience A/S, Herlev, Denmark.
Pokaż więcej
Źródło:
PloS one [PLoS One] 2018 Mar 29; Vol. 13 (3), pp. e0194458. Date of Electronic Publication: 2018 Mar 29 (Print Publication: 2018).
Typ publikacji:
Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms:
Sex Characteristics*
Aging/*metabolism
Basement Membrane/*metabolism
Collagen/*metabolism
Extracellular Matrix/*metabolism
Adult ; Age Factors ; Aged ; Aged, 80 and over ; Female ; Humans ; Male ; Middle Aged ; Pregnancy
Czasopismo naukowe
Tytuł:
Non-invasive quantification of collagen turnover in renal transplant recipients.
Autorzy:
Stribos EGD; Department of Pharmaceutical Technology and Biopharmacy, University of Groningen, Groningen Research Institute of Pharmacy, Groningen, The Netherlands.; Department of Internal Medicine, Division of Nephrology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Nielsen SH; Nordic Bioscience A/S, Herlev, Denmark.; Department of Biotechnology and Biomedicine, Technical University of Denmark, Lyngby, Denmark.
Brix S; Department of Biotechnology and Biomedicine, Technical University of Denmark, Lyngby, Denmark.
Karsdal MA; Nordic Bioscience A/S, Herlev, Denmark.
Seelen MA; Department of Internal Medicine, Division of Nephrology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
van Goor H; Department of Pathology and Medical Biology, Division of Pathology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Bakker SJL; Department of Internal Medicine, Division of Nephrology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Olinga P; Department of Pharmaceutical Technology and Biopharmacy, University of Groningen, Groningen Research Institute of Pharmacy, Groningen, The Netherlands.
Mutsaers HAM; Department of Pharmaceutical Technology and Biopharmacy, University of Groningen, Groningen Research Institute of Pharmacy, Groningen, The Netherlands.
Genovese F; Nordic Bioscience A/S, Herlev, Denmark.
Pokaż więcej
Źródło:
PloS one [PLoS One] 2017 Apr 21; Vol. 12 (4), pp. e0175898. Date of Electronic Publication: 2017 Apr 21 (Print Publication: 2017).
Typ publikacji:
Journal Article
MeSH Terms:
Kidney Transplantation*
Collagen/*metabolism
Adult ; Aged ; Biomarkers/metabolism ; Cohort Studies ; Enzyme-Linked Immunosorbent Assay ; Female ; Humans ; Male ; Middle Aged
Czasopismo naukowe
Tytuł:
High levels of biomarkers of collagen remodeling are associated with increased mortality in COPD - results from the ECLIPSE study.
Autorzy:
Sand JM; Nordic Bioscience, Herlev, Denmark. .; Section of Social Medicine, Institute of Public Health, University of Copenhagen, Copenhagen, Denmark. .
Leeming DJ; Nordic Bioscience, Herlev, Denmark.
Byrjalsen I; Nordic Bioscience, Herlev, Denmark.
Bihlet AR; Nordic Bioscience, Herlev, Denmark.
Lange P; Section of Social Medicine, Institute of Public Health, University of Copenhagen, Copenhagen, Denmark.; Section of Respiratory Medicine, Hvidovre Hospital, Hvidovre, Denmark.
Tal-Singer R; Respiratory Therapy Area Unit, GSK Research and Development, King of Prussia, PA, USA.
Miller BE; Respiratory Therapy Area Unit, GSK Research and Development, King of Prussia, PA, USA.
Karsdal MA; Nordic Bioscience, Herlev, Denmark.
Vestbo J; Centre for Respiratory Medicine and Allergy, Manchester Academic Science Centre, The University of Manchester and University Hospital South Manchester NHS Foundation Trust, Manchester, UK.
Pokaż więcej
Źródło:
Respiratory research [Respir Res] 2016 Oct 04; Vol. 17 (1), pp. 125. Date of Electronic Publication: 2016 Oct 04.
Typ publikacji:
Journal Article; Observational Study; Research Support, Non-U.S. Gov't
MeSH Terms:
Airway Remodeling*
Collagen/*blood
Extracellular Matrix/*metabolism
Lung/*metabolism
Peptide Fragments/*blood
Pulmonary Disease, Chronic Obstructive/*blood
Pulmonary Disease, Chronic Obstructive/*mortality
Age Factors ; Aged ; Biomarkers/blood ; Case-Control Studies ; Collagen Type IV/blood ; Disease Progression ; Dyspnea/blood ; Dyspnea/mortality ; Dyspnea/physiopathology ; Exercise Tolerance ; Female ; Humans ; Kaplan-Meier Estimate ; Longitudinal Studies ; Lung/physiopathology ; Male ; Middle Aged ; Predictive Value of Tests ; Prognosis ; Proportional Hazards Models ; Pulmonary Disease, Chronic Obstructive/diagnosis ; Pulmonary Disease, Chronic Obstructive/physiopathology ; Pulmonary Emphysema/blood ; Pulmonary Emphysema/mortality ; Pulmonary Emphysema/physiopathology ; Risk Factors ; Smoking/adverse effects ; Smoking/mortality ; Time Factors ; Up-Regulation
Czasopismo naukowe
Tytuł:
Markers of Collagen Remodeling Detect Clinically Significant Fibrosis in Chronic Hepatitis C Patients.
Autorzy:
Nielsen MJ; Nordic Bioscience A/S, Fibrosis Biology and Biomarkers, Herlev, Denmark; Department of Gastroenterology and Hepatology, Odense University Hospital, University of Southern Denmark, Faculty of Health Science, Odense, Denmark.
Kazankov K; Department of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark.
Leeming DJ; Nordic Bioscience A/S, Fibrosis Biology and Biomarkers, Herlev, Denmark.
Karsdal MA; Nordic Bioscience A/S, Fibrosis Biology and Biomarkers, Herlev, Denmark.
Krag A; Department of Gastroenterology and Hepatology, Odense University Hospital, University of Southern Denmark, Faculty of Health Science, Odense, Denmark.
Barrera F; Storr Liver Unit, Westmead Millennium Institute, Westmead Hospital and University of Sydney, Sydney, Australia.
McLeod D; Department of Anatomical Pathology, Institute of Clinical Pathology and Medical Research, Westmead Hospital, Sydney, Australia.
George J; Storr Liver Unit, Westmead Millennium Institute, Westmead Hospital and University of Sydney, Sydney, Australia.
Grønbæk H; Department of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark.
Pokaż więcej
Źródło:
PloS one [PLoS One] 2015 Sep 25; Vol. 10 (9), pp. e0137302. Date of Electronic Publication: 2015 Sep 25 (Print Publication: 2015).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Collagen/*metabolism
Hepatitis C, Chronic/*metabolism
Liver Cirrhosis/*metabolism
Adult ; Biomarkers/metabolism ; Female ; Hepatitis C, Chronic/pathology ; Hepatitis C, Chronic/therapy ; Humans ; Liver Cirrhosis/pathology ; Liver Cirrhosis/therapy ; Male ; Middle Aged ; Retrospective Studies
Czasopismo naukowe
Tytuł:
Evaluation of cartilage damage by measuring collagen degradation products in joint extracts in a traumatic model of osteoarthritis.
Autorzy:
Nielsen RH; Nordic Bioscience, Herlev Hovedgade 207, DK-2730 Herlev, Denmark.
Stoop R
Leeming DJ
Stolina M
Qvist P
Christiansen C
Karsdal MA
Pokaż więcej
Źródło:
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals [Biomarkers] 2008 Feb; Vol. 13 (1), pp. 79-87.
Typ publikacji:
Journal Article
MeSH Terms:
Cartilage Diseases/*diagnosis
Cartilage, Articular/*metabolism
Collagen/*metabolism
Knee Joint/*metabolism
Osteoarthritis, Knee/*metabolism
Animals ; Anterior Cruciate Ligament Injuries ; Collagen Type I/metabolism ; Collagen Type II/metabolism ; Knee Joint/pathology ; Osteoarthritis, Knee/pathology ; Rats
Czasopismo naukowe
Tytuł:
Collagen turnover is associated with cardiovascular autonomic and peripheral neuropathy in type 1 diabetes: novel pathophysiological mechanism?
Autorzy:
Hansen, Christian S.Aff1, IDs12933023018918_cor1
Rasmussen, Daniel G. K.
Hansen, Tine W.
Nielsen, Signe HolmAff2, Aff3
Theilade, SimoneAff1, Aff4
Karsdal, Morten A.
Genovese, Federica
Rossing, PeterAff1, Aff4
Pokaż więcej
Źródło:
Cardiovascular Diabetology. 22(1)
Czasopismo naukowe
Tytuł:
Endotrophin is a risk marker of complications in CANagliflozin cardioVascular Assessment Study (CANVAS): a randomized controlled trial
Autorzy:
Rasmussen, Daniel Guldager KringAff1, IDs12933022016667_cor1
Hansen, Michael K.
Blair, Joseph
Jatkoe, Timothy A.
Neal, BruceAff4, Aff5, Aff6
Karsdal, Morten A.
Genovese, Federica
Pokaż więcej
Źródło:
Cardiovascular Diabetology. 21(1)
Czasopismo naukowe
Tytuł:
Nintedanib modulates type III collagen turnover in viable precision-cut lung slices from bleomycin-treated rats and patients with pulmonary fibrosis
Autorzy:
Hesse, ChristinaAff1, Aff2
Beneke, ValerieAff1, Aff2
Konzok, SebastianAff1, Aff2
Diefenbach, Claudia
Bülow Sand, Jannie Marie
Rønnow, Sarah Rank
Karsdal, Morten Asser
Jonigk, DannyAff5, Aff6
Sewald, KatherinaAff1, Aff2
Braun, ArminAff1, Aff2
Leeming, Diana Julie
Wollin, LutzAff3, IDs12931022021164_cor12
Pokaż więcej
Źródło:
Respiratory Research. 23(1)
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies