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    Wyświetlanie 1-4 z 4
    Tytuł:
    Virtual Screening of Hepatitis B Virus Pre-Genomic RNA as a Novel Therapeutic Target.
    Autorzy:
    Olenginski LT; Department of Chemistry and Biochemistry, University of Maryland, College Park, MD 20742, USA.
    Kasprzak WK; Bioinformatics and Computational Science Program, Frederick National Laboratory for Cancer Research, National Cancer Institute, Frederick, MD 21702, USA.
    Attionu SK; Department of Chemistry and Biochemistry, University of Maryland, College Park, MD 20742, USA.
    Shapiro BA; RNA Biology Laboratory, National Cancer Institute, Frederick, MD 21702, USA.
    Dayie TK; Department of Chemistry and Biochemistry, University of Maryland, College Park, MD 20742, USA.
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    Źródło:
    Molecules (Basel, Switzerland) [Molecules] 2023 Feb 14; Vol. 28 (4). Date of Electronic Publication: 2023 Feb 14.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Hepatitis B virus*
    Hepatitis B*
    Humans ; Virus Replication ; RNA, Viral/genetics ; Genomics
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    RNA⁻Protein Interactions Prevent Long RNA Duplex Formation: Implications for the Design of RNA-Based Therapeutics.
    Autorzy:
    Bindewald E; RNA Biology Laboratory, Basic Science Program, Frederick National Laboratory for Cancer Research supported by the National Cancer Institute, Frederick, MD 21702, USA. .
    Dai L; RNA Biology Laboratory, National Cancer Institute, Frederick, MD 21702, USA. .
    Kasprzak WK; RNA Biology Laboratory, Basic Science Program, Frederick National Laboratory for Cancer Research supported by the National Cancer Institute, Frederick, MD 21702, USA. .
    Kim T; RNA Biology Laboratory, National Cancer Institute, Frederick, MD 21702, USA. .
    Gu S; RNA Biology Laboratory, National Cancer Institute, Frederick, MD 21702, USA. .
    Shapiro BA; RNA Biology Laboratory, National Cancer Institute, Frederick, MD 21702, USA. .
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    Źródło:
    Molecules (Basel, Switzerland) [Molecules] 2018 Dec 15; Vol. 23 (12). Date of Electronic Publication: 2018 Dec 15.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    RNA, Double-Stranded/*metabolism
    RNA, Double-Stranded/*therapeutic use
    RNA-Binding Proteins/*metabolism
    Base Sequence ; Endoribonucleases/metabolism ; HEK293 Cells ; Humans ; Protein Binding ; RNA, Double-Stranded/chemistry ; RNA, Ribosomal/metabolism ; Ribosomes/metabolism ; Solvents
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Ribosomal frameshifting in the CCR5 mRNA is regulated by miRNAs and the NMD pathway.
    Autorzy:
    Belew AT; 1] Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, Maryland 20742, USA [2].
    Meskauskas A; 1] Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, Maryland 20742, USA [2] Department of Biotechnology and Microbiology, Vilnius University, Vilnius, LT 03101, Lithuania [3].
    Musalgaonkar S; Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, Maryland 20742, USA.
    Advani VM; Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, Maryland 20742, USA.
    Sulima SO; 1] Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, Maryland 20742, USA [2] VIB Center for the Biology of Disease, KU Leuven, Campus Gasthuisberg, Herestraat 49, bus 602, 3000 Leuven, Belgium.
    Kasprzak WK; Basic Science Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland 21702, USA.
    Shapiro BA; Basic Research Laboratory, National Cancer Institute, Frederick, Maryland 21702, USA.
    Dinman JD; Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, Maryland 20742, USA.
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    Źródło:
    Nature [Nature] 2014 Aug 21; Vol. 512 (7514), pp. 265-9. Date of Electronic Publication: 2014 Jul 09.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
    MeSH Terms:
    Nonsense Mediated mRNA Decay*
    Frameshifting, Ribosomal/*genetics
    MicroRNAs/*genetics
    RNA, Messenger/*genetics
    RNA, Messenger/*metabolism
    Receptors, CCR5/*genetics
    Amino Acid Sequence ; Base Sequence ; Binding Sites ; Cell Survival ; Codon, Nonsense/genetics ; HeLa Cells ; Humans ; Models, Molecular ; Molecular Sequence Data ; Nucleic Acid Conformation ; RNA, Messenger/chemistry ; Receptors, Interleukin/genetics ; Regulatory Sequences, Ribonucleic Acid ; Ribosomes/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Genomic analyses reveal broad impact of miR-137 on genes associated with malignant transformation and neuronal differentiation in glioblastoma cells.
    Autorzy:
    Tamim S; Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America.
    Vo DT; Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America.
    Uren PJ; Molecular and Computational Biology Section, Division of Biological Sciences, University of Southern California, Los Angeles, California, United States of America.
    Qiao M; Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America.
    Bindewald E; Basic Science Program, SAIC-Frederick, Inc., Center for Cancer Research Nanobiology Program, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America.
    Kasprzak WK; Basic Science Program, SAIC-Frederick, Inc., Center for Cancer Research Nanobiology Program, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America.
    Shapiro BA; Center for Cancer Research Nanobiology Program, National Cancer Institute, Frederick, Maryland, California.
    Nakaya HI; Department of Clinical Analyses and Toxicology, Institute of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brazil.
    Burns SC; Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America.
    Araujo PR; Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America.
    Nakano I; Department of Neurological Surgery, James Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, United States of America.
    Radek AJ; Epicentre (An Illumina Company), Madison, Wisconsin, United States of America.
    Kuersten S; Epicentre (An Illumina Company), Madison, Wisconsin, United States of America.
    Smith AD; Molecular and Computational Biology Section, Division of Biological Sciences, University of Southern California, Los Angeles, California, United States of America.
    Penalva LO; Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America ; Department of Cellular and Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America.
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    Źródło:
    PloS one [PLoS One] 2014 Jan 22; Vol. 9 (1), pp. e85591. Date of Electronic Publication: 2014 Jan 22 (Print Publication: 2014).
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Cell Differentiation/*genetics
    Cell Transformation, Neoplastic/*genetics
    Genetic Predisposition to Disease/*genetics
    MicroRNAs/*genetics
    Neurons/*metabolism
    Apoptosis/genetics ; Blotting, Western ; Brain Neoplasms/genetics ; Brain Neoplasms/pathology ; Cell Movement/genetics ; Cell Proliferation ; Cell Transformation, Neoplastic/pathology ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic ; Gene Regulatory Networks ; Genome-Wide Association Study ; Glioblastoma/genetics ; Glioblastoma/pathology ; Humans ; Models, Genetic ; Neoplasm Proteins/genetics ; Neoplasm Proteins/metabolism ; Neurogenesis/genetics ; Neurons/pathology ; Oligonucleotide Array Sequence Analysis ; Reverse Transcriptase Polymerase Chain Reaction
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
      Wyświetlanie 1-4 z 4

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