Autor: "Kazani, Shamsah D." - OpacWWW

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Tytuł:: Prostaglandin D 2 metabolites activate asthmatic patient-derived type 2 innate lymphoid cells and eosinophils via the DP 2 receptor.
Autorzy:: Carstensen S; Department of Biomarker Analysis and Development, Clinical Airway Research, Fraunhofer Institute of Toxicology and Experimental Medicine, Hannover, Germany.
Gress C; Department of Biomarker Analysis and Development, Clinical Airway Research, Fraunhofer Institute of Toxicology and Experimental Medicine, Hannover, Germany.
Erpenbeck VJ; Novartis Pharma AG, Basel, Switzerland.
Kazani SD; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.
Hohlfeld JM; Department of Biomarker Analysis and Development, Clinical Airway Research, Fraunhofer Institute of Toxicology and Experimental Medicine, Hannover, Germany.; German Center for Lung Research (BREATH), Hannover, Germany.; Department of Respiratory Medicine, Hannover Medical School, Hannover, Germany.
Sandham DA; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.
Müller M; Department of Biomarker Analysis and Development, Clinical Airway Research, Fraunhofer Institute of Toxicology and Experimental Medicine, Hannover, Germany. .; Pokaż więcej
Źródło:: Respiratory research [Respir Res] 2021 Oct 07; Vol. 22 (1), pp. 262. Date of Electronic Publication: 2021 Oct 07.
Typ publikacji:: Comparative Study; Journal Article
MeSH Terms:: Asthma/*drug therapy
Eosinophils/*drug effects
Lymphocytes/*drug effects
Prostaglandin D2/*pharmacology
Receptors, Immunologic/*agonists
Receptors, Prostaglandin/*agonists
Adolescent ; Adult ; Aged ; Asthma/immunology ; Asthma/metabolism ; Cell Movement/drug effects ; Cell Shape/drug effects ; Cells, Cultured ; Eosinophils/immunology ; Eosinophils/metabolism ; Female ; Humans ; Indoleacetic Acids/pharmacology ; Interleukin-13/metabolism ; Interleukin-5/metabolism ; Lymphocytes/immunology ; Lymphocytes/metabolism ; Male ; Middle Aged ; Prostaglandin Antagonists/pharmacology ; Prostaglandin D2/analogs & derivatives ; Pyridines/pharmacology ; Receptors, Immunologic/metabolism ; Receptors, Prostaglandin/metabolism ; Signal Transduction ; Young Adult

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