Autor: "Keene KL" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: DNA methylation analyses identify an intronic ZDHHC6 locus associated with time to recurrent stroke in the Vitamin Intervention for Stroke Prevention (VISP) clinical trial.
Autorzy:: Davis Armstrong NM; Department of Biology, East Carolina University, Greenville, NC, United States of America.
Chen WM; Center for Public Health Genomics, University of Virginia, Charlottesville, VA, United States of America.; Department of Public Health Sciences, University of Virginia, Charlottesville, VA, United States of America.
Hsu FC; Department of Biostatistics and Data Science, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC, United States of America.
Brewer MS; Department of Biology, East Carolina University, Greenville, NC, United States of America.
Cullell N; Stroke Pharmacogenomics and Genetics, Fundació Docència i Recerca Mútua Terrassa, Hospital Universitari Mútua de Terrassa, Terrassa, Barcelona, Spain.; Stroke Pharmacogenomics and Genetics, Sant Pau Institute of Research, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Fernández-Cadenas I; Stroke Pharmacogenomics and Genetics, Fundació Docència i Recerca Mútua Terrassa, Hospital Universitari Mútua de Terrassa, Terrassa, Barcelona, Spain.; Stroke Pharmacogenomics and Genetics, Sant Pau Institute of Research, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Williams SR; Department of Neurology, University of Virginia, Charlottesville, VA, United States of America.
Sale MM; Center for Public Health Genomics, University of Virginia, Charlottesville, VA, United States of America.; Department of Public Health Sciences, University of Virginia, Charlottesville, VA, United States of America.
Worrall BB; Department of Public Health Sciences, University of Virginia, Charlottesville, VA, United States of America.; Department of Neurology, University of Virginia, Charlottesville, VA, United States of America.
Keene KL; Department of Biology, East Carolina University, Greenville, NC, United States of America.; Center for Health Disparities, Brody School of Medicine, East Carolina University, Greenville, NC, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2021 Jul 12; Vol. 16 (7), pp. e0254562. Date of Electronic Publication: 2021 Jul 12 (Print Publication: 2021).
Typ publikacji:: Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Acyltransferases/*genetics
DNA Methylation/*genetics
Stroke/*genetics
Stroke/*prevention & control
Aged ; Epigenome/genetics ; Female ; Humans ; Male ; Middle Aged ; Vitamins/therapeutic use

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Skocz do pozycji: 2.

Tytuł:: Multi-omic analysis of stroke recurrence in African Americans from the Vitamin Intervention for Stroke Prevention (VISP) clinical trial.
Autorzy:: Davis Armstrong NM; Department of Biology, East Carolina University, Greenville, North Carolina, United States of America.
Spragley KJ; Department of Biology, East Carolina University, Greenville, North Carolina, United States of America.
Chen WM; Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia, United States of America.; Department of Public Health Sciences, University of Virginia, Charlottesville, Virginia, United States of America.
Hsu FC; Division of Public Health Sciences, Department of Biostatistics and Data Science, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America.
Brewer MS; Department of Biology, East Carolina University, Greenville, North Carolina, United States of America.
Horn PJ; Department of Biology, East Carolina University, Greenville, North Carolina, United States of America.
Williams SR; Department of Neurology, University of Virginia, Charlottesville, Virginia, United States of America.
Sale MM; Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia, United States of America.; Department of Public Health Sciences, University of Virginia, Charlottesville, Virginia, United States of America.
Worrall BB; Department of Public Health Sciences, University of Virginia, Charlottesville, Virginia, United States of America.; Department of Neurology, University of Virginia, Charlottesville, Virginia, United States of America.
Keene KL; Department of Biology, East Carolina University, Greenville, North Carolina, United States of America.; Center for Health Disparities, Brody School of Medicine, East Carolina University, Greenville, North Carolina, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2021 Mar 04; Vol. 16 (3), pp. e0247257. Date of Electronic Publication: 2021 Mar 04 (Print Publication: 2021).
Typ publikacji:: Clinical Trial; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Genetic Loci*
Genetic Variation*
Metabolomics*
Stroke*/blood
Stroke*/ethnology
Stroke*/genetics
Stroke*/prevention & control
Black or African American/*genetics
DNA Methylation/*drug effects
Vitamins/*administration & dosage
Aged ; Female ; Humans ; Male ; Middle Aged

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Skocz do pozycji: 3.

Tytuł:: Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes.
Autorzy:: Ng MC; Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America; Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America.
Shriner D; Center for Research on Genomics and Global Health, National Human Genome Research Institute, Bethesda, Maryland, United States of America.
Chen BH; Program on Genomics and Nutrition, School of Public Health, University of California Los Angeles, Los Angeles, California, United States of America; Center for Metabolic Disease Prevention, School of Public Health, University of California Los Angeles, Los Angeles, California, United States of America.
Li J; Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America.
Chen WM; Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia, United States of America; Department of Public Health Sciences, University of Virginia, Charlottesville, Virginia, United States of America.
Guo X; Institute for Translational Genomics and Population Sciences, Los Angeles BioMedical Research Institute at Harbor-UCLA Medical Center, Torrance, California, United States of America.
Liu J; Department of Medicine, University of Mississippi Medical Center, Jackson, Mississippi, United States of America.
Bielinski SJ; Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, United States of America.
Yanek LR; The GeneSTAR Research Program, Division of General Internal Medicine, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.
Nalls MA; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America.
Comeau ME; Center for Public Health Genomics, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America; Department of Biostatistical Sciences, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America.
Rasmussen-Torvik LJ; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America.
Jensen RA; Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, United States of America; Department of Medicine, University of Washington, Seattle, Washington, United States of America.
Evans DS; San Francisco Coordinating Center, California Pacific Medical Center Research Institute, San Francisco, California, United States of America.
Sun YV; Department of Epidemiology and Biomedical Informatics, Emory University, Atlanta, Georgia, United States of America.
An P; Division of Statistical Genomics, Washington University School of Medicine, St. Louis, Missouri, United States of America.
Patel SR; Division of Sleep Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.
Lu Y; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.
Long J; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America.
Armstrong LL; Division of Endocrinology, Metabolism and Molecular Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America.
Wagenknecht L; Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America.
Yang L; Department of Biostatistical Sciences, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America.
Snively BM; Department of Biostatistical Sciences, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America.
Palmer ND; Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America; Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America.
Mudgal P; Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America.
Langefeld CD; Center for Public Health Genomics, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America; Department of Biostatistical Sciences, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America.
Keene KL; Department of Biology, Center for Health Disparities, East Carolina University, Greenville, North Carolina, United States of America.
Freedman BI; Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America.
Mychaleckyj JC; Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia, United States of America; Department of Public Health Sciences, University of Virginia, Charlottesville, Virginia, United States of America.
Nayak U; Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia, United States of America; Department of Public Health Sciences, University of Virginia, Charlottesville, Virginia, United States of America.
Raffel LJ; Medical Genetics Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States of America.
Goodarzi MO; Medical Genetics Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States of America.
Chen YD; Institute for Translational Genomics and Population Sciences, Los Angeles BioMedical Research Institute at Harbor-UCLA Medical Center, Torrance, California, United States of America.
Taylor HA Jr; Department of Medicine, University of Mississippi Medical Center, Jackson, Mississippi, United States of America; Jackson State University, Tougaloo College, Jackson, Mississippi, United States of America.
Correa A; Department of Medicine, University of Mississippi Medical Center, Jackson, Mississippi, United States of America.
Sims M; Department of Medicine, University of Mississippi Medical Center, Jackson, Mississippi, United States of America.
Couper D; Collaborative Studies Coordinating Center, Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Pankow JS; Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, Minnesota, United States of America.
Boerwinkle E; Human Genetics Center, University of Texas Health Science Center at Houston, Houston, Texas, United States of America.
Adeyemo A; Center for Research on Genomics and Global Health, National Human Genome Research Institute, Bethesda, Maryland, United States of America.
Doumatey A; Center for Research on Genomics and Global Health, National Human Genome Research Institute, Bethesda, Maryland, United States of America.
Chen G; Center for Research on Genomics and Global Health, National Human Genome Research Institute, Bethesda, Maryland, United States of America.
Mathias RA; The GeneSTAR Research Program, Division of General Internal Medicine, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America; Division of Allergy and Clinical Immunology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.
Vaidya D; The GeneSTAR Research Program, Division of General Internal Medicine, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America.
Singleton AB; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America.
Zonderman AB; Laboratory of Personality and Cognition, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America.
Igo RP Jr; Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, Ohio, United States of America.
Sedor JR; Department of Medicine, Case Western Reserve University, MetroHealth System campus, Cleveland, Ohio, United States of America; Department of Physiology and Biophysics, Case Western Reserve University, Cleveland, Ohio, United States of America.
Kabagambe EK; Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America.
Siscovick DS; Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, United States of America; Department of Medicine, University of Washington, Seattle, Washington, United States of America; Department of Epidemiology, University of Washington, Seattle, Washington, United States of America.
McKnight B; Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, United States of America; Department of Biostatistics, University of Washington, Seattle, Washington, United States of America.
Rice K; Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, United States of America; Department of Biostatistics, University of Washington, Seattle, Washington, United States of America.
Liu Y; Department of Epidemiology and Prevention, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America.
Hsueh WC; Department of Medicine, University of California, San Francisco, California, United States of America.
Zhao W; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan, United States of America.
Bielak LF; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan, United States of America.
Kraja A; Division of Statistical Genomics, Washington University School of Medicine, St. Louis, Missouri, United States of America.
Province MA; Division of Statistical Genomics, Washington University School of Medicine, St. Louis, Missouri, United States of America.
Bottinger EP; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.
Gottesman O; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.
Cai Q; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America.
Zheng W; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America.
Blot WJ; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee; International Epidemiology Institute, Rockville, Maryland, United States of America.
Lowe WL; Division of Endocrinology, Metabolism and Molecular Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America.
Pacheco JA; Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America.
Crawford DC; Center for Human Genetics Research and Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee, United States of America.
Grundberg E; Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom.
Rich SS; Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia, United States of America.
Hayes MG; Division of Endocrinology, Metabolism and Molecular Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America.
Shu XO; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America.
Loos RJ; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.
Borecki IB; Division of Statistical Genomics, Washington University School of Medicine, St. Louis, Missouri, United States of America.
Peyser PA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan, United States of America.
Cummings SR; San Francisco Coordinating Center, California Pacific Medical Center Research Institute, San Francisco, California, United States of America.
Psaty BM; Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, United States of America; Department of Medicine, University of Washington, Seattle, Washington, United States of America; Department of Epidemiology, University of Washington, Seattle, Washington, United States of America; Department of Health Services, University of Washington, Seattle, Washington, United States of America.
Fornage M; Human Genetics Center, University of Texas Health Science Center at Houston, Houston, Texas, United States of America.
Iyengar SK; Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, Ohio, United States of America.
Evans MK; Health Disparities Unit, National Institute on Aging, National Institutes of Health, Baltimore Maryland, United States of America.
Becker DM; The GeneSTAR Research Program, Division of General Internal Medicine, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America; Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America.
Kao WH; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America.
Wilson JG; Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, Mississippi, United States of America.
Rotter JI; Institute for Translational Genomics and Population Sciences, Los Angeles BioMedical Research Institute at Harbor-UCLA Medical Center, Torrance, California, United States of America.
Sale MM; Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia, United States of America; Department of Medicine, University of Virginia, Charlottesville, Virginia, United States of America; Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, Virginia, United States of America.
Liu S; Program on Genomics and Nutrition, School of Public Health, University of California Los Angeles, Los Angeles, California, United States of America; Department of Epidemiology, University of California Los Angeles, Los Angeles, California, United States of America; Departments of Epidemiology and Medicine, Brown University, Providence, Rhode Island, United States of America.
Rotimi CN; Center for Research on Genomics and Global Health, National Human Genome Research Institute, Bethesda, Maryland, United States of America.
Bowden DW; Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America; Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America.; Pokaż więcej
Corporate Authors:: FIND Consortium
eMERGE Consortium
DIAGRAM Consortium
MuTHER Consortium
MEta-analysis of type 2 DIabetes in African Americans Consortium
Źródło:: PLoS genetics [PLoS Genet] 2014 Aug 07; Vol. 10 (8), pp. e1004517. Date of Electronic Publication: 2014 Aug 07 (Print Publication: 2014).
Typ publikacji:: Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:: Diabetes Mellitus, Type 2/*genetics
HLA-B27 Antigen/*genetics
HMGA2 Protein/*genetics
KCNQ1 Potassium Channel/*genetics
Mutant Chimeric Proteins/*genetics
Transcription Factor 7-Like 2 Protein/*genetics
Black or African American/genetics ; Diabetes Mellitus, Type 2/pathology ; Genome-Wide Association Study ; Humans ; Polymorphism, Single Nucleotide

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Skocz do pozycji: 4.

Tytuł:: Genome-wide meta-analysis of homocysteine and methionine metabolism identifies five one carbon metabolism loci and a novel association of ALDH1L1 with ischemic stroke.
Autorzy:: Williams SR; Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia, United States of America; Cardiovascular Research Center, University of Virginia, Charlottesville, Virginia, United States of America.
Yang Q; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America; The Framingham Heart Study, Framingham, Massachusetts, United States of America.
Chen F; Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia, United States of America.
Liu X; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America.
Keene KL; Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia, United States of America; Department of Public Health Sciences, University of Virginia, Charlottesville, Virginia, United States of America; Department of Biology, East Carolina University, Greenville, North Carolina, United States of America; Center for Health Disparities Research, East Carolina University, Greenville, North Carolina, United States of America.
Jacques P; Jean Mayer USDA Human Nutrition Research Center on Aging and Friedman School of Nutrition Science and Policy, Tufts University, Boston, Massachusetts, United States of America.
Chen WM; Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia, United States of America.
Weinstein G; Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, United States of America.
Hsu FC; Department of Biostatistical Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America.
Beiser A; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America; Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, United States of America.
Wang L; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic College of Medicine, Rochester, Minnesota, United States of America.
Bookman E; National Human Genome Research Institute, Bethesda, Maryland, United States of America.
Doheny KF; Center for Inherited Disease Research, Johns Hopkins University, Baltimore, Maryland, United States of America.
Wolf PA; Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, United States of America.
Zilka M; Center for Inherited Disease Research, Johns Hopkins University, Baltimore, Maryland, United States of America.
Selhub J; Jean Mayer USDA Human Nutrition Research Center on Aging and Friedman School of Nutrition Science and Policy, Tufts University, Boston, Massachusetts, United States of America.
Nelson S; Department of Biostatistics, University of Washington, Seattle, Washington, United States of America.
Gogarten SM; Department of Biostatistics, University of Washington, Seattle, Washington, United States of America.
Worrall BB; Department of Public Health Sciences, University of Virginia, Charlottesville, Virginia, United States of America; Department of Neurology University of Virginia, Charlottesville, Virginia, United States of America.
Seshadri S; Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, United States of America.
Sale MM; Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia, United States of America; Department of Medicine, University of Virginia, Charlottesville, Virginia, United States of America; Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, Virginia, United States of America.; Pokaż więcej
Corporate Authors:: Genomics and Randomized Trials Network
Framingham Heart Study
Źródło:: PLoS genetics [PLoS Genet] 2014 Mar 20; Vol. 10 (3), pp. e1004214. Date of Electronic Publication: 2014 Mar 20 (Print Publication: 2014).
Typ publikacji:: Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Aldehyde Dehydrogenase/*genetics
Homocysteine/*metabolism
Methionine/*metabolism
Stroke/*genetics
Carbon/metabolism ; Folic Acid/metabolism ; Genome-Wide Association Study ; Genotype ; Homocysteine/genetics ; Humans ; Methionine/genetics ; Oxidoreductases Acting on CH-NH Group Donors ; Stroke/pathology ; Vitamin B 12

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Skocz do pozycji: 5.

Tytuł:: Evidence for two independent associations with type 1 diabetes at the 12q13 locus.
Autorzy:: Keene KL; Department of Biochemistry and Molecular Genetics, UVA School of Medicine, University of Virginia, Charlottesville, VA, USA.
Quinlan AR
Hou X
Hall IM
Mychaleckyj JC
Onengut-Gumuscu S
Concannon P; Pokaż więcej
Źródło:: Genes and immunity [Genes Immun] 2012 Jan; Vol. 13 (1), pp. 66-70. Date of Electronic Publication: 2011 Aug 18.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Chromosomes, Human, Pair 12*
Genetic Loci*
Genetic Predisposition to Disease*
Diabetes Mellitus, Type 1/*genetics
Genetic Association Studies ; Humans ; Polymorphism, Single Nucleotide ; Siblings

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Tytuł:: Chromosome 7p linkage and association study for diabetes related traits and type 2 diabetes in an African-American population enriched for nephropathy.
Autorzy:: Leak TS; Center for Human Genomics, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Langefeld CD
Keene KL
Gallagher CJ
Lu L
Mychaleckyj JC
Rich SS
Freedman BI
Bowden DW
Sale MM; Pokaż więcej
Źródło:: BMC medical genetics [BMC Med Genet] 2010 Feb 08; Vol. 11, pp. 22. Date of Electronic Publication: 2010 Feb 08.
Typ publikacji:: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Black People/*genetics
Chromosomes, Human, Pair 7/*genetics
Diabetes Mellitus, Type 2/*genetics
Diabetic Nephropathies/*etiology
Genetic Linkage/*genetics
Kidney Failure, Chronic/*genetics
Polymorphism, Single Nucleotide/*genetics
Adult ; Age of Onset ; Body Mass Index ; Case-Control Studies ; Diabetes Mellitus, Type 2/complications ; Diabetes Mellitus, Type 2/ethnology ; Diabetic Nephropathies/ethnology ; Female ; Genome-Wide Association Study ; Genotype ; Germinal Center Kinases ; Humans ; Insulin-Like Growth Factor Binding Protein 1/genetics ; Insulin-Like Growth Factor Binding Protein 3 ; Insulin-Like Growth Factor Binding Proteins/genetics ; Interleukin-6/genetics ; Kidney Failure, Chronic/complications ; Kidney Failure, Chronic/ethnology ; Male ; Microsatellite Repeats/genetics ; Middle Aged ; Protein Serine-Threonine Kinases/genetics ; Risk Factors

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Tytuł:: Variants in intron 13 of the ELMO1 gene are associated with diabetic nephropathy in African Americans.
Autorzy:: Leak TS; Center for Human Genomics, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Perlegas PS
Smith SG
Keene KL
Hicks PJ
Langefeld CD
Mychaleckyj JC
Rich SS
Kirk JK
Freedman BI
Bowden DW
Sale MM; Pokaż więcej
Źródło:: Annals of human genetics [Ann Hum Genet] 2009 Mar; Vol. 73 (2), pp. 152-9. Date of Electronic Publication: 2009 Jan 23.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Genetic Predisposition to Disease*
Adaptor Proteins, Signal Transducing/*genetics
Black or African American/*genetics
Diabetic Nephropathies/*ethnology
Diabetic Nephropathies/*genetics
Aged ; Diabetes Mellitus, Type 2/complications ; Female ; Humans ; Introns ; Male ; Middle Aged ; Polymorphism, Single Nucleotide

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Skocz do pozycji: 8.

Tytuł:: The uncoupling protein 1 gene, UCP1, is expressed in mammalian islet cells and associated with acute insulin response to glucose in African American families from the IRAS Family Study.
Autorzy:: Sale MM; Center for Human Genomics, Wake Forest University School of Medicine, Winston-Salem, USA. />Hsu FC
Palmer ND
Gordon CJ
Keene KL
Borgerink HM
Sharma AJ
Bergman RN
Taylor KD
Saad MF
Norris JM; Pokaż więcej
Źródło:: BMC endocrine disorders [BMC Endocr Disord] 2007 Mar 30; Vol. 7, pp. 1. Date of Electronic Publication: 2007 Mar 30.
Typ publikacji:: Journal Article

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