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Wyświetlanie 1-20 z 123
Tytuł:
Targeted detection and quantitation of histone modifications from 1,000 cells.
Autorzy:
Abshiru NA; Departments of Chemistry, Molecular Biosciences, and the Proteomics Center of Excellence, Northwestern University, Evanston, IL, United States of America.
Sikora JW; Departments of Chemistry, Molecular Biosciences, and the Proteomics Center of Excellence, Northwestern University, Evanston, IL, United States of America.
Camarillo JM; Departments of Chemistry, Molecular Biosciences, and the Proteomics Center of Excellence, Northwestern University, Evanston, IL, United States of America.
Morris JA; Departments of Chemistry, Molecular Biosciences, and the Proteomics Center of Excellence, Northwestern University, Evanston, IL, United States of America.
Compton PD; Departments of Chemistry, Molecular Biosciences, and the Proteomics Center of Excellence, Northwestern University, Evanston, IL, United States of America.
Lee T; Division of Hematology/Oncology, Department of Medicine, Weill Cornell Medicine, New York, NY, United States of America.
Neelamraju Y; Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, VA, United States of America.
Haddox S; Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, VA, United States of America.
Sheridan C; Division of Hematology/Oncology, Department of Medicine, Weill Cornell Medicine, New York, NY, United States of America.
Carroll M; Division of Hematology and Oncology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States of America.
Cripe LD; Indiana University/Melvin and Bren Simon Cancer Center, Indianapolis, IN, United States of America.
Tallman MS; Memorial Sloan Kettering Cancer Center, New York, NY, United States of America.
Paietta EM; Montefiore Medical Center-Moses Campus, Bronx, NY, United States of America.
Melnick AM; Division of Hematology/Oncology, Department of Medicine, Weill Cornell Medicine, New York, NY, United States of America.
Thomas PM; Departments of Chemistry, Molecular Biosciences, and the Proteomics Center of Excellence, Northwestern University, Evanston, IL, United States of America.
Garrett-Bakelman FE; Division of Hematology/Oncology, Department of Medicine, Weill Cornell Medicine, New York, NY, United States of America.; Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, VA, United States of America.; Division of Hematology/Medical Oncology, Department of Medicine, University of Virginia, Charlottesville, VA, United States of America.
Kelleher NL; Departments of Chemistry, Molecular Biosciences, and the Proteomics Center of Excellence, Northwestern University, Evanston, IL, United States of America.
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Źródło:
PloS one [PLoS One] 2020 Oct 26; Vol. 15 (10), pp. e0240829. Date of Electronic Publication: 2020 Oct 26 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Histones/*genetics
Histones/*metabolism
Proteomics/*methods
Acetylation ; Cell Line ; Chromatography, Liquid/methods ; Humans ; Methylation ; Peptides/chemistry ; Protein Processing, Post-Translational/genetics ; Tandem Mass Spectrometry/methods
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Proteoforms as the next proteomics currency.
Autorzy:
Smith LM; Department of Chemistry, University of Wisconsin, 1101 University Avenue, Madison, WI 53706-1396, USA. .
Kelleher NL; Departments of Chemistry and Molecular Biosciences and Feinberg School of Medicine, Northwestern University, Evanston, IL 60208, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2018 Mar 09; Vol. 359 (6380), pp. 1106-1107. Date of Electronic Publication: 2018 Mar 08.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Proteomics*
Protein Isoforms/*chemistry
Protein Isoforms/*genetics
Animals ; Genetic Variation ; Humans ; Peptides/chemistry ; Protein Processing, Post-Translational
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Top-down proteomics with mass spectrometry imaging: a pilot study towards discovery of biomarkers for neurodevelopmental disorders.
Autorzy:
Ye H; State Key Laboratory of Natural Medicines, Key Lab of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing, PR China; Department of Pharmaceutical Analysis, China Pharmaceutical University, Nanjing, PR China; School of Pharmacy, University of Wisconsin Madison, Madison, Wisconsin, United States of America.
Mandal R; Department of Neurology, University of Wisconsin Madison, Madison, Wisconsin, United States of America.
Catherman A; Proteomics Center of Excellence, Northwestern University, Evanston, Illinois, United States of America.
Thomas PM; Proteomics Center of Excellence, Northwestern University, Evanston, Illinois, United States of America.
Kelleher NL; Proteomics Center of Excellence, Northwestern University, Evanston, Illinois, United States of America.
Ikonomidou C; Department of Neurology, University of Wisconsin Madison, Madison, Wisconsin, United States of America.
Li L; School of Pharmacy, University of Wisconsin Madison, Madison, Wisconsin, United States of America; Department of Chemistry, University of Wisconsin Madison, Madison, Wisconsin, United States of America.
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Źródło:
PloS one [PLoS One] 2014 Apr 07; Vol. 9 (4), pp. e92831. Date of Electronic Publication: 2014 Apr 07 (Print Publication: 2014).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Mass Spectrometry*
Proteomics*
Brain/*metabolism
Brain Diseases/*metabolism
Nerve Tissue Proteins/*metabolism
Animals ; Animals, Newborn ; Biomarkers ; Brain/pathology ; Brain Chemistry/drug effects ; Brain Diseases/pathology ; Dizocilpine Maleate/pharmacology ; Excitatory Amino Acid Antagonists/pharmacology ; Gene Expression Regulation/drug effects ; Nerve Tissue Proteins/antagonists & inhibitors ; Rats ; Rats, Wistar
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Strain-specific proteogenomics accelerates the discovery of natural products via their biosynthetic pathways.
Autorzy:
Albright JC; Departments of Chemistry, Molecular Biosciences, and the Feinberg School of Medicine, Northwestern University, 2170 Campus Drive, Evanston, IL, 60208, USA.
Goering AW
Doroghazi JR
Metcalf WW
Kelleher NL
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Źródło:
Journal of industrial microbiology & biotechnology [J Ind Microbiol Biotechnol] 2014 Feb; Vol. 41 (2), pp. 451-9. Date of Electronic Publication: 2013 Nov 19.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Genome, Bacterial*
Biological Products/*metabolism
Proteomics/*methods
Streptomyces/*genetics
Biological Products/chemistry ; Biosynthetic Pathways/genetics ; Genomics/methods ; Mass Spectrometry ; Siderophores/genetics ; Siderophores/metabolism ; Species Specificity ; Streptomyces/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
A protease for 'middle-down' proteomics.
Autorzy:
Wu C; Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.
Tran JC
Zamdborg L
Durbin KR
Li M
Ahlf DR
Early BP
Thomas PM
Sweedler JV
Kelleher NL
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Źródło:
Nature methods [Nat Methods] 2012 Jun 17; Vol. 9 (8), pp. 822-4. Date of Electronic Publication: 2012 Jun 17.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Proteolysis*
Peptides/*analysis
Peptides/*metabolism
Proteomics/*methods
Serine Endopeptidases/*metabolism
HeLa Cells ; Humans ; Mass Spectrometry ; Peptides/chemistry ; Protein Isoforms/chemistry ; Protein Isoforms/metabolism ; Protein Processing, Post-Translational ; Serine Endopeptidases/chemistry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Mapping intact protein isoforms in discovery mode using top-down proteomics.
Autorzy:
Tran JC; Department of Chemistry and Biochemistry, and the Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.
Zamdborg L
Ahlf DR
Lee JE
Catherman AD
Durbin KR
Tipton JD
Vellaichamy A
Kellie JF
Li M
Wu C
Sweet SM
Early BP
Siuti N
LeDuc RD
Compton PD
Thomas PM
Kelleher NL
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Źródło:
Nature [Nature] 2011 Oct 30; Vol. 480 (7376), pp. 254-8. Date of Electronic Publication: 2011 Oct 30.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Protein Isoforms/*analysis
Protein Isoforms/*chemistry
Proteome/*analysis
Proteome/*chemistry
Proteomics/*methods
Alternative Splicing ; Cell Line ; Cellular Senescence/genetics ; DNA Damage ; Databases, Protein ; HMGA1a Protein/analysis ; HMGA1b Protein/analysis ; HeLa Cells ; Humans ; Phenotype ; Protein Processing, Post-Translational ; Proteolysis ; Proteomics/instrumentation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
A proteomics approach to discovering natural products and their biosynthetic pathways.
Autorzy:
Bumpus SB; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.
Evans BS
Thomas PM
Ntai I
Kelleher NL
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Źródło:
Nature biotechnology [Nat Biotechnol] 2009 Oct; Vol. 27 (10), pp. 951-6. Date of Electronic Publication: 2009 Sep 20.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Biological Products/*biosynthesis
Proteomics/*methods
Bacillus/genetics ; Bacillus/metabolism ; Biological Products/analysis ; Biological Products/metabolism ; Cluster Analysis ; Gene Regulatory Networks ; Lipopeptides/metabolism ; Mass Spectrometry/methods ; Metabolic Networks and Pathways ; Pantetheine/analogs & derivatives ; Pantetheine/metabolism ; Peptide Biosynthesis, Nucleic Acid-Independent ; Peptide Fragments/metabolism ; Peptide Synthases/metabolism ; Polyketide Synthases/metabolism ; Streptomyces/genetics ; Streptomyces/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Decoding protein modifications using top-down mass spectrometry.
Autorzy:
Siuti N; Department of Chemistry, University of Illinois at Urbana-Champaign, 53 Roger Adams Laboratory, 600 South Matthews Avenue, Urbana, Illinois 61801, USA.
Kelleher NL
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Źródło:
Nature methods [Nat Methods] 2007 Oct; Vol. 4 (10), pp. 817-21.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Mass Spectrometry/*methods
Proteomics/*methods
Chromatin/chemistry ; Membrane Proteins/chemistry ; Protein Isoforms/chemistry ; Protein Processing, Post-Translational ; Tandem Mass Spectrometry/methods
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Identification of Plasmodium falciparum proteoforms from liver stage models
Autorzy:
Winer, Benjamin
Edgel, Kimberly A.
Zou, XiaoyanAff1, Aff2
Sellau, JulieAff4, Aff6
Hadiwidjojo, SriAff1, Aff2
Garver, Lindsey S.
McDonough, Christin E.
Kelleher, Neil L.
Thomas, Paul M.
Villasante, Eileen
Ploss, Alexander
Gerbasi, Vincent R.Aff1, Aff5
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Źródło:
Malaria Journal. 19(1)
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 123

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