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Tytuł:
A Comparison of the Efficacy of Antivenoms and Varespladib against the In Vitro Pre-Synaptic Neurotoxicity of Thai and Javanese Russell's Viper ( Daboia spp.) Venoms.
Autorzy:
Lay M; Monash Venom Group, Department of Pharmacology, Biomedical Discovery Institute, Monash University, Clayton, VIC 3800, Australia.
Hodgson WC; Monash Venom Group, Department of Pharmacology, Biomedical Discovery Institute, Monash University, Clayton, VIC 3800, Australia.
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Źródło:
Toxins [Toxins (Basel)] 2024 Mar 01; Vol. 16 (3). Date of Electronic Publication: 2024 Mar 01.
Typ publikacji:
Journal Article
MeSH Terms:
Daboia*
Neurotoxicity Syndromes*
Acetates*
Indoles*
Keto Acids*
Humans ; Animals ; Antivenins ; Venoms ; Indonesia ; Thailand
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Investigating the association between blood metabolites and telomere length: A mendelian randomization study.
Autorzy:
Gao C; Head and Neck Surgeons, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fujian, China.
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Źródło:
PloS one [PLoS One] 2024 Mar 08; Vol. 19 (3), pp. e0298172. Date of Electronic Publication: 2024 Mar 08 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Genome-Wide Association Study*
Mendelian Randomization Analysis*
Humans ; Databases, Factual ; Keto Acids ; Taurocholic Acid ; Telomere/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Direct Aroylation of Olefins through a Cobalt/Photoredox-Catalyzed Decarboxylative and Dehydrogenative Coupling with α-Oxo Acids.
Autorzy:
Davies AM; Department of Chemistry, University of Kansas, 1567 Irving Hill Rd., Lawrence, KS 66045, USA.
D Hernandez R; Department of Chemistry, University of Kansas, 1567 Irving Hill Rd., Lawrence, KS 66045, USA.
Tunge JA; Department of Chemistry, University of Kansas, 1567 Irving Hill Rd., Lawrence, KS 66045, USA.
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Źródło:
Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2022 Dec 27; Vol. 28 (72), pp. e202202781. Date of Electronic Publication: 2022 Nov 21.
Typ publikacji:
Journal Article
MeSH Terms:
Keto Acids*
Alkenes*
Cobalt ; Catalysis ; Styrenes
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Analysis of Content of 2-Oxoacids in Rat Brain Extracts Using High-Performance Liquid Chromatography.
Autorzy:
Tashlitsky VN; Faculty of Chemistry, Lomonosov Moscow State University, Moscow, 119991, Russia.
Artiukhov AV; Belozersky Institute of Physicochemical Biology, Lomonosov Moscow State University, Moscow, 119991, Russia.; Department of Biochemistry, Sechenov University, Moscow, 119991, Russia.
Fedorova NV; Belozersky Institute of Physicochemical Biology, Lomonosov Moscow State University, Moscow, 119991, Russia.
Sukonnikov MA; Faculty of Chemistry, Lomonosov Moscow State University, Moscow, 119991, Russia.
Ksenofontov AL; Belozersky Institute of Physicochemical Biology, Lomonosov Moscow State University, Moscow, 119991, Russia. .
Bunik VI; Belozersky Institute of Physicochemical Biology, Lomonosov Moscow State University, Moscow, 119991, Russia.; Department of Biochemistry, Sechenov University, Moscow, 119991, Russia.; Faculty of Bioengineering and Bioinformatics, Lomonosov Moscow State University, Moscow, 119991, Russia.
Baratova LA; Belozersky Institute of Physicochemical Biology, Lomonosov Moscow State University, Moscow, 119991, Russia. .
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Źródło:
Biochemistry. Biokhimiia [Biochemistry (Mosc)] 2022 Apr; Vol. 87 (4), pp. 356-365.
Typ publikacji:
Journal Article
MeSH Terms:
Keto Acids*
Pyruvic Acid*
Animals ; Brain ; Chromatography, High Pressure Liquid/methods ; Mammals ; Rats
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A Palladium-Catalyzed 4CzIPN-Mediated Decarboxylative Acylation Reaction of O-Methyl Ketoximes with α-Keto Acids under Visible Light.
Autorzy:
Wang C; Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science Soochow University, Suzhou 215123, China.
Yang S; Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science Soochow University, Suzhou 215123, China.
Huang Z; Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science Soochow University, Suzhou 215123, China.
Zhao Y; Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science Soochow University, Suzhou 215123, China.; School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang 453000, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2022 Mar 18; Vol. 27 (6). Date of Electronic Publication: 2022 Mar 18.
Typ publikacji:
Journal Article
MeSH Terms:
Keto Acids*
Palladium*
Acylation ; Catalysis ; Light ; Oximes
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Transamination-Like Reaction Catalyzed by Leucine Dehydrogenase for Efficient Co-Synthesis of α-Amino Acids and α-Keto Acids.
Autorzy:
Mu X; Laboratory of Brewing Microbiology and Applied Enzymology, School of Biotechnology, Jiangnan University, Wuxi 214122, China.; Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi 214122, China.; Institute of Industrial Technology, Suqian Jiangnan University, Suqian 223800, China.
Feng X; Laboratory of Brewing Microbiology and Applied Enzymology, School of Biotechnology, Jiangnan University, Wuxi 214122, China.
Wu T; Laboratory of Brewing Microbiology and Applied Enzymology, School of Biotechnology, Jiangnan University, Wuxi 214122, China.
Zhou F; Laboratory of Brewing Microbiology and Applied Enzymology, School of Biotechnology, Jiangnan University, Wuxi 214122, China.
Nie Y; Laboratory of Brewing Microbiology and Applied Enzymology, School of Biotechnology, Jiangnan University, Wuxi 214122, China.
Xu Y; Laboratory of Brewing Microbiology and Applied Enzymology, School of Biotechnology, Jiangnan University, Wuxi 214122, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2021 Nov 30; Vol. 26 (23). Date of Electronic Publication: 2021 Nov 30.
Typ publikacji:
Journal Article
MeSH Terms:
Amino Acids/*biosynthesis
Keto Acids/*metabolism
Leucine Dehydrogenase/*metabolism
Amination ; Amino Acids/chemistry ; Ammonium Compounds/metabolism ; Bacillus cereus/enzymology ; Catalysis ; Hydrogen-Ion Concentration ; Keto Acids/chemistry ; Kinetics ; NAD/metabolism ; Oxidation-Reduction ; Substrate Specificity
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Convenient Genetic Encoding of Phenylalanine Derivatives through Their α-Keto Acid Precursors.
Autorzy:
Liu L; Jiangsu Key Laboratory of Druggability of Biopharmaceuticals, Department of Biochemistry, School of Life Science and Technology, China Pharmaceutical University, Nanjing 210009, China.
Wang B; Jiangsu Key Laboratory of Druggability of Biopharmaceuticals, Department of Biochemistry, School of Life Science and Technology, China Pharmaceutical University, Nanjing 210009, China.
Li S; Jiangsu Key Laboratory of Druggability of Biopharmaceuticals, Department of Biochemistry, School of Life Science and Technology, China Pharmaceutical University, Nanjing 210009, China.
Xu F; Jiangsu Key Laboratory of Druggability of Biopharmaceuticals, Department of Biochemistry, School of Life Science and Technology, China Pharmaceutical University, Nanjing 210009, China.
He Q; Jiangsu Key Laboratory of Druggability of Biopharmaceuticals, Department of Biochemistry, School of Life Science and Technology, China Pharmaceutical University, Nanjing 210009, China.
Pan C; Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, School of Medicine, Southeast University, Nanjing 210009, China.
Gao X; Jiangsu Key Laboratory of Druggability of Biopharmaceuticals, Department of Biochemistry, School of Life Science and Technology, China Pharmaceutical University, Nanjing 210009, China.
Yao W; Jiangsu Key Laboratory of Druggability of Biopharmaceuticals, Department of Biochemistry, School of Life Science and Technology, China Pharmaceutical University, Nanjing 210009, China.
Song X; Jiangsu Key Laboratory of Druggability of Biopharmaceuticals, Department of Biochemistry, School of Life Science and Technology, China Pharmaceutical University, Nanjing 210009, China.
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Źródło:
Biomolecules [Biomolecules] 2021 Sep 14; Vol. 11 (9). Date of Electronic Publication: 2021 Sep 14.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Genetic Code*
Keto Acids/*metabolism
Phenylalanine/*genetics
Escherichia coli/metabolism ; Fluorescence ; Green Fluorescent Proteins/metabolism ; Keto Acids/chemistry ; Phenylalanine/chemistry ; Pyridoxal Phosphate/metabolism ; Substrate Specificity
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Transition-metal-free Synthesis of tetra-substituted Vinyl Iodides by Cascade Sequential Reaction of α-Keto Acids, 1-Iodoalkynes, and Alkyl Halides.
Autorzy:
Zeng X; Jiangsu Province Key Laboratory for Inflammation and Molecular Drug Target School of Pharmacy, Nantong University, Nantong, 226001, P. R. China.
Cheng Z; Jiangsu Province Key Laboratory for Inflammation and Molecular Drug Target School of Pharmacy, Nantong University, Nantong, 226001, P. R. China.
Xie Y; Jiangsu Province Key Laboratory for Inflammation and Molecular Drug Target School of Pharmacy, Nantong University, Nantong, 226001, P. R. China.
Gu Y; Jiangsu Province Key Laboratory for Inflammation and Molecular Drug Target School of Pharmacy, Nantong University, Nantong, 226001, P. R. China.
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Źródło:
Chemistry, an Asian journal [Chem Asian J] 2023 Jan 17; Vol. 18 (2), pp. e202201117. Date of Electronic Publication: 2022 Dec 13.
Typ publikacji:
Journal Article
MeSH Terms:
Iodides*
Transition Elements*
Keto Acids ; Catalysis ; Vinyl Compounds
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Caloric restriction improves glycaemic control without reducing plasma branched-chain amino acids or keto-acids in obese men.
Autorzy:
Sayda MH; MRC-Versus Arthritis Centre for Musculoskeletal Ageing Research, University of Nottingham, Derby, UK.; National Centre for Sport and Exercise Medicine, Nottingham, UK.
Abdul Aziz MH; MRC-Versus Arthritis Centre for Musculoskeletal Ageing Research, University of Nottingham, Derby, UK.; Nottingham NIHR Biomedical Research Centre, Nottingham, UK.
Gharahdaghi N; MRC-Versus Arthritis Centre for Musculoskeletal Ageing Research, University of Nottingham, Derby, UK.; Nottingham NIHR Biomedical Research Centre, Nottingham, UK.
Wilkinson DJ; MRC-Versus Arthritis Centre for Musculoskeletal Ageing Research, University of Nottingham, Derby, UK.; Nottingham NIHR Biomedical Research Centre, Nottingham, UK.; National Centre for Sport and Exercise Medicine, Nottingham, UK.
Greenhaff PL; MRC-Versus Arthritis Centre for Musculoskeletal Ageing Research, University of Nottingham, Derby, UK.; Nottingham NIHR Biomedical Research Centre, Nottingham, UK.; National Centre for Sport and Exercise Medicine, Nottingham, UK.
Phillips BE; MRC-Versus Arthritis Centre for Musculoskeletal Ageing Research, University of Nottingham, Derby, UK.; Nottingham NIHR Biomedical Research Centre, Nottingham, UK.; National Centre for Sport and Exercise Medicine, Nottingham, UK.
Smith K; MRC-Versus Arthritis Centre for Musculoskeletal Ageing Research, University of Nottingham, Derby, UK.; Nottingham NIHR Biomedical Research Centre, Nottingham, UK.; National Centre for Sport and Exercise Medicine, Nottingham, UK.
Idris I; MRC-Versus Arthritis Centre for Musculoskeletal Ageing Research, University of Nottingham, Derby, UK.; Nottingham NIHR Biomedical Research Centre, Nottingham, UK.
Atherton PJ; MRC-Versus Arthritis Centre for Musculoskeletal Ageing Research, University of Nottingham, Derby, UK. .; Nottingham NIHR Biomedical Research Centre, Nottingham, UK. .; National Centre for Sport and Exercise Medicine, Nottingham, UK. .; Division of Medical Sciences and Graduate Entry Medicine, University of Nottingham, Royal Derby Hospital Centre, Derby, DE22 3DT, UK. .
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Źródło:
Scientific reports [Sci Rep] 2022 Nov 11; Vol. 12 (1), pp. 19273. Date of Electronic Publication: 2022 Nov 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Amino Acids, Branched-Chain*/metabolism
Insulin Resistance*
Male ; Humans ; Adult ; Middle Aged ; Young Adult ; Caloric Restriction ; Glycemic Control ; Leucine ; Isoleucine ; Keto Acids ; Blood Glucose/metabolism ; Obesity ; Weight Loss ; Overweight/therapy ; Valine
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Brain Protein Acylation System Responds to Seizures in the Rat Model of PTZ-Induced Epilepsy.
Autorzy:
Zavileyskiy LG; Faculty of Bioengineering and Bioinformatics, Lomonosov Moscow State University, 119234 Moscow, Russia.
Aleshin VA; Department of Biokinetics, A.N. Belozersky Institute of Physicochemical Biology, Lomonosov Moscow State University, 119234 Moscow, Russia.; Department of Biochemistry, Sechenov University, 119048 Moscow, Russia.
Kaehne T; Institute of Experimental Internal Medicine, Otto von Guericke University, 39106 Magdeburg, Germany.
Karlina IS; N.V. Sklifosovsky Institute of Clinical Medicine, Sechenov First Moscow State Medical University, 119435 Moscow, Russia.
Artiukhov AV; Department of Biokinetics, A.N. Belozersky Institute of Physicochemical Biology, Lomonosov Moscow State University, 119234 Moscow, Russia.; Department of Biochemistry, Sechenov University, 119048 Moscow, Russia.
Maslova MV; Faculty of Biology, Lomonosov Moscow State University, 119234 Moscow, Russia.
Graf AV; Department of Biokinetics, A.N. Belozersky Institute of Physicochemical Biology, Lomonosov Moscow State University, 119234 Moscow, Russia.; Faculty of Biology, Lomonosov Moscow State University, 119234 Moscow, Russia.
Bunik VI; Faculty of Bioengineering and Bioinformatics, Lomonosov Moscow State University, 119234 Moscow, Russia.; Department of Biokinetics, A.N. Belozersky Institute of Physicochemical Biology, Lomonosov Moscow State University, 119234 Moscow, Russia.; Department of Biochemistry, Sechenov University, 119048 Moscow, Russia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Oct 14; Vol. 23 (20). Date of Electronic Publication: 2022 Oct 14.
Typ publikacji:
Journal Article
MeSH Terms:
Sirtuin 3*/metabolism
Epilepsy*/chemically induced
Animals ; Rats ; Pentylenetetrazole ; Sirtuin 2/metabolism ; NAD/metabolism ; Acylation ; Acyl Coenzyme A/metabolism ; Seizures/chemically induced ; Brain/metabolism ; Ketoglutarate Dehydrogenase Complex/metabolism ; Keto Acids ; Oxidoreductases/metabolism ; Pyruvates ; gamma-Aminobutyric Acid/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Magnetic Separation of Oxoacid of Boron from Salt-Lake Brine by Synergistically Enhanced Boron Adsorbents of Glucose-Functionalized SiO 2 and Graphene.
Autorzy:
Luo Q; Key Laboratory of Comprehensive and Highly Efficient Utilization of Salt Lake Resources, Qinghai Institute of Salt Lakes, Chinese Academy of Sciences, Xining 810008, China.; Key Laboratory of Salt Lake Resources Chemistry of Qinghai Province, Qinghai Institute of Salt Lakes, Chinese Academy of Sciences, Xining 810008, China.
Wang X; College of Chemical Engineering, Xinjiang University, Urumqi 830046, China.
Dong M; Key Laboratory of Comprehensive and Highly Efficient Utilization of Salt Lake Resources, Qinghai Institute of Salt Lakes, Chinese Academy of Sciences, Xining 810008, China.; Key Laboratory of Salt Lake Resources Chemistry of Qinghai Province, Qinghai Institute of Salt Lakes, Chinese Academy of Sciences, Xining 810008, China.
Huang X; College of Chemical Engineering, Xinjiang University, Urumqi 830046, China.
Wu Z; Key Laboratory of Comprehensive and Highly Efficient Utilization of Salt Lake Resources, Qinghai Institute of Salt Lakes, Chinese Academy of Sciences, Xining 810008, China.; Key Laboratory of Salt Lake Resources Chemistry of Qinghai Province, Qinghai Institute of Salt Lakes, Chinese Academy of Sciences, Xining 810008, China.
Li J; Key Laboratory of Comprehensive and Highly Efficient Utilization of Salt Lake Resources, Qinghai Institute of Salt Lakes, Chinese Academy of Sciences, Xining 810008, China.; Key Laboratory of Salt Lake Resources Chemistry of Qinghai Province, Qinghai Institute of Salt Lakes, Chinese Academy of Sciences, Xining 810008, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Sep 26; Vol. 23 (19). Date of Electronic Publication: 2022 Sep 26.
Typ publikacji:
Journal Article
MeSH Terms:
Graphite*/chemistry
Water Pollutants, Chemical*
Adsorption ; Alkalies ; Boron ; Glucose ; Keto Acids ; Lakes ; Magnetic Phenomena ; Salts ; Silicon ; Silicon Dioxide/chemistry ; Spectroscopy, Fourier Transform Infrared
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Dielectric Study of Tetraalkylammonium and Tetraalkylphosphonium Levulinate Ionic Liquids.
Autorzy:
Kripotou S; Laboratory of Electronic Devices and Materials, Department of Electrical and Electronics Engineering, University of West Attica, 12244 Athens, Greece.
Tsonos G; Laboratory of Electronic Devices and Materials, Department of Electrical and Electronics Engineering, University of West Attica, 12244 Athens, Greece.
Mezzetta A; Department of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy.
Mero A; Department of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy.
Guazzelli L; Department of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy.
Moutzouris K; Laboratory of Electronic Devices and Materials, Department of Electrical and Electronics Engineering, University of West Attica, 12244 Athens, Greece.
Stavrakas I; Laboratory of Electronic Devices and Materials, Department of Electrical and Electronics Engineering, University of West Attica, 12244 Athens, Greece.
Tsonos C; Department of Physics, University of Thessaly, 35100 Lamia, Greece.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 May 18; Vol. 23 (10). Date of Electronic Publication: 2022 May 18.
Typ publikacji:
Journal Article
MeSH Terms:
Ionic Liquids*/chemistry
Anions ; Electric Conductivity ; Ions/chemistry ; Keto Acids ; Viscosity
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Compound α-keto acid tablet supplementation alleviates chronic kidney disease progression via inhibition of the NF-kB and MAPK pathways.
Autorzy:
Wang M; Department of Nephrology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Ave, Wuhan, 430030, Hubei, China.
Xu H; Department of Nephrology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Ave, Wuhan, 430030, Hubei, China.
Chong Lee Shin OL; Department of Nephrology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Ave, Wuhan, 430030, Hubei, China.
Li L; Department of Nutrition and Food Hygiene, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Ave, Wuhan, 430030, Hubei, China.
Gao H; Department of Nutrition, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Ave, Wuhan, 430030, Hubei, China.
Zhao Z; Department of Nephrology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Ave, Wuhan, 430030, Hubei, China.
Zhu F; Department of Nephrology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Ave, Wuhan, 430030, Hubei, China.
Zhu H; Department of Nephrology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Ave, Wuhan, 430030, Hubei, China.
Liang W; Department of Nephrology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Ave, Wuhan, 430030, Hubei, China.
Qian K; Department of Nephrology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Ave, Wuhan, 430030, Hubei, China.
Zhang C; Department of Nephrology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Ave, Wuhan, 430030, Hubei, China.
Zeng R; Department of Nephrology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Ave, Wuhan, 430030, Hubei, China.
Zhou H; Department of Nephrology, Jinhua Hospital of Zhejiang University, 365 Renmin East Ave, Jinhua, 321000, Zhejiang, China. .
Yao Y; Department of Nephrology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Ave, Wuhan, 430030, Hubei, China. .; Department of Nutrition, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Ave, Wuhan, 430030, Hubei, China. .
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Źródło:
Journal of translational medicine [J Transl Med] 2019 Apr 11; Vol. 17 (1), pp. 122. Date of Electronic Publication: 2019 Apr 11.
Typ publikacji:
Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Dietary Supplements*
Disease Progression*
MAP Kinase Signaling System*/drug effects
Keto Acids/*therapeutic use
NF-kappa B/*metabolism
Renal Insufficiency, Chronic/*drug therapy
Renal Insufficiency, Chronic/*pathology
Animals ; Apoptosis/drug effects ; Diet, Protein-Restricted ; Female ; Humans ; Inflammation/pathology ; Keto Acids/pharmacology ; Male ; Mice, Inbred C57BL ; Middle Aged ; Probability ; Renal Insufficiency, Chronic/etiology ; Renal Insufficiency, Chronic/physiopathology ; Reperfusion Injury/complications ; Survival Analysis ; Tablets
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Dietary supplementation with ketoacids protects against CKD-induced oxidative damage and mitochondrial dysfunction in skeletal muscle of 5/6 nephrectomised rats.
Autorzy:
Wang D; Department of Traditional Chinese Medicine, Shenzhen Hospital, Southern Medical University, Shenzhen, 518000, Guangdong, China. .; Department of Nephrology, Shenzhen Traditional Chinese Medicine Hospital, Guangzhou University of Traditional Chinese Medicine, Shenzhen, 518033, Guangdong, China. .; Department of Nephrology, Ruikang Affiliated Hospital, Guangxi University of Chinese Medicine, Nanning, 530011, Guangxi, China. .
Wei L; Department of Traditional Chinese Medicine, Shenzhen Hospital, Southern Medical University, Shenzhen, 518000, Guangdong, China.
Yang Y; Department of Pharmacology, Guangdong Key Laboratory for R&D of Natural Drug, Guangdong Medical University, Zhanjiang, 524023, Guangdong, China.
Liu H; Department of Nephrology, Ruikang Affiliated Hospital, Guangxi University of Chinese Medicine, Nanning, 530011, Guangxi, China.
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Źródło:
Skeletal muscle [Skelet Muscle] 2018 May 31; Vol. 8 (1), pp. 18. Date of Electronic Publication: 2018 May 31.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Dietary Supplements*
Keto Acids/*therapeutic use
Mitochondria, Muscle/*drug effects
Muscular Atrophy/*drug therapy
Oxidative Stress/*drug effects
Renal Insufficiency, Chronic/*complications
Animals ; Drug Evaluation, Preclinical/methods ; Keto Acids/pharmacology ; Kidney/physiopathology ; Male ; Mitochondria, Muscle/physiology ; Muscle Proteins/metabolism ; Muscle, Skeletal/metabolism ; Muscle, Skeletal/physiopathology ; Muscular Atrophy/etiology ; Muscular Atrophy/metabolism ; Muscular Atrophy/physiopathology ; Nephrectomy ; Proteasome Endopeptidase Complex/biosynthesis ; Proteasome Endopeptidase Complex/genetics ; Rats, Sprague-Dawley ; Renal Insufficiency, Chronic/metabolism ; Renal Insufficiency, Chronic/physiopathology ; Ubiquitin/biosynthesis ; Ubiquitin/genetics ; Up-Regulation/drug effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Determination of Branched-Chain Keto Acids in Serum and Muscles Using High Performance Liquid Chromatography-Quadrupole Time-of-Flight Mass Spectrometry.
Autorzy:
Zhang Y; State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China. you_.
Yin B; State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China. youda_.
Li R; State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China. .
He P; State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China. .
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2018 Jan 11; Vol. 23 (1). Date of Electronic Publication: 2018 Jan 11.
Typ publikacji:
Journal Article
MeSH Terms:
Chromatography, High Pressure Liquid*
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization*
Keto Acids/*metabolism
Muscles/*metabolism
Animals ; Biomarkers ; Keto Acids/blood ; Keto Acids/chemistry ; Molecular Structure ; Reproducibility of Results ; Swine
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Expressing 2-keto acid pathway enzymes significantly increases photosynthetic isobutanol production.
Autorzy:
Xie H; Microbial Chemistry, Department of Chemistry-Ångström Laboratory, Uppsala University, Box 523, 75120, Uppsala, Sweden.
Lindblad P; Microbial Chemistry, Department of Chemistry-Ångström Laboratory, Uppsala University, Box 523, 75120, Uppsala, Sweden. .
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Źródło:
Microbial cell factories [Microb Cell Fact] 2022 Feb 01; Vol. 21 (1), pp. 17. Date of Electronic Publication: 2022 Feb 01.
Typ publikacji:
Journal Article
MeSH Terms:
Butanols/*metabolism
Keto Acids/*metabolism
Synechocystis/*genetics
Synechocystis/*metabolism
Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Biosynthetic Pathways ; Carbon Dioxide/metabolism ; Metabolic Engineering ; Photosynthesis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Characteristics of Biotin lipoyl attachment and 2-oxoacid dehydrogenase acyltransferase of the parasitic nematode Haemonchus contortus and its modulatory functions on goat PBMCs in vitro.
Autorzy:
Aimulajiang K; State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, Xinjiang Medical University, Urumqi, Xinjiang, China.; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, Jiangsu, China.
Wen Z; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, Jiangsu, China.
Naqvi MA; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, Jiangsu, China.
Liang M; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, Jiangsu, China.
Tian X; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, Jiangsu, China.; Xinxiang Key Laboratory of Pathogenic Biology, School of Basic Medical Sciences, Xinxiang Medical University, Xinxiang, Henan, China.
Feng K; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, Jiangsu, China.
Muhammad Khand F; Faculty of Veterinary Sciences, Shaheed Benazir Bhutto University of Veterinary and Animal Sciences Sakrand, Sindh, Pakistan.
Memon MA; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, Jiangsu, China.
Xu L; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, Jiangsu, China.
Song X; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, Jiangsu, China.
Li X; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, Jiangsu, China.
Yan R; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, Jiangsu, China.
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Źródło:
Parasite immunology [Parasite Immunol] 2021 Dec; Vol. 43 (12), pp. e12895. Date of Electronic Publication: 2021 Nov 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Haemonchiasis*
Haemonchus*/genetics
Acyltransferases/metabolism ; Animals ; Biotin/metabolism ; Dihydrolipoamide Dehydrogenase/metabolism ; Goats/parasitology ; Helminth Proteins ; Keto Acids/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Expanding the Reactive Sulfur Metabolome: Intracellular and Efflux Measurements of Small Oxoacids of Sulfur (SOS) and H 2 S in Human Primary Vascular Cell Culture.
Autorzy:
Scrivner O; Department of Chemistry and Biochemistry, Baylor University, Waco, TX 76798, USA.
Ismaeel A; Department of Biology, Baylor University, Waco, TX 76798, USA.
Kumar MR; Department of Chemistry and Biochemistry, Baylor University, Waco, TX 76798, USA.
Sorokolet K; Department of Chemistry and Biochemistry, Baylor University, Waco, TX 76798, USA.
Koutakis P; Department of Biology, Baylor University, Waco, TX 76798, USA.
Farmer PJ; Department of Chemistry and Biochemistry, Baylor University, Waco, TX 76798, USA.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2021 Nov 26; Vol. 26 (23). Date of Electronic Publication: 2021 Nov 26.
Typ publikacji:
Journal Article
MeSH Terms:
Cardiovascular System/*metabolism
Hydrogen Sulfide/*metabolism
Keto Acids/*metabolism
Metabolome/*genetics
Arteries/metabolism ; Biological Transport/genetics ; Cell Culture Techniques ; Coronary Vessels/metabolism ; Humans ; Myocytes, Smooth Muscle/metabolism ; Oxidation-Reduction ; Signal Transduction/genetics ; Sulfur/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
In vivo plug-and-play: a modular multi-enzyme single-cell catalyst for the asymmetric amination of ketoacids and ketones.
Autorzy:
Farnberger JE; Austrian Centre of Industrial Biotechnology, ACIB GmbH, c/o University of Graz, Heinrichstrasse 28, 8010, Graz, Austria.
Lorenz E; Genetics of Prokaryotes, Faculty of Biology & CeBiTec, Bielefeld University, 33501, Bielefeld, Germany.
Richter N; Austrian Centre of Industrial Biotechnology, ACIB GmbH, c/o University of Graz, Heinrichstrasse 28, 8010, Graz, Austria.
Wendisch VF; Genetics of Prokaryotes, Faculty of Biology & CeBiTec, Bielefeld University, 33501, Bielefeld, Germany. .
Kroutil W; Austrian Centre of Industrial Biotechnology, ACIB GmbH, c/o University of Graz, Heinrichstrasse 28, 8010, Graz, Austria. .; Institute of Chemistry, University of Graz, NAWI Graz, BioTechMed Graz, Heinrichstrasse 28, 8010, Graz, Austria. .
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Źródło:
Microbial cell factories [Microb Cell Fact] 2017 Jul 28; Vol. 16 (1), pp. 132. Date of Electronic Publication: 2017 Jul 28.
Typ publikacji:
Journal Article
MeSH Terms:
Amines/*metabolism
Bacterial Proteins/*metabolism
Escherichia coli/*metabolism
Keto Acids/*metabolism
Ketones/*metabolism
Transaminases/*metabolism
Amination ; Amines/chemistry ; Bacterial Proteins/genetics ; Biocatalysis ; Isoleucine/metabolism ; Keto Acids/chemistry ; Ketones/chemistry ; Leucine/metabolism ; NAD/chemistry ; NAD/metabolism ; Plasmids ; Stereoisomerism ; Substrate Specificity ; Transaminases/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Can keto/amino acids reduce oxidative stress in peritoneal dialysis patients with hypoalbuminemia?
Autorzy:
Çankaya E; Department of Nephrology, Medical Faculty, Atatürk University, Erzurum, Turkey.
Bilen Y; Department of Hematology, Medical Faculty, Adıyaman University, Erzurum, Turkey.
Uyanık A; Department of Nephrology, Medical Faculty, Atatürk University, Erzurum, Turkey.
Dogan H; Medical Biology Genetics, Medical Faculty, Atatürk University, Erzurum, Turkey.
Kızıltunç A; Medical Biochemistry, Medical Faculty, Atatürk University, Erzurum, Turkey.
Sevinç C; Department of Nephrology, Medical Faculty, Atatürk University, Erzurum, Turkey.
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Źródło:
Seminars in dialysis [Semin Dial] 2021 Sep; Vol. 34 (5), pp. 375-379. Date of Electronic Publication: 2021 Apr 01.
Typ publikacji:
Journal Article
MeSH Terms:
Hypoalbuminemia*/etiology
Peritoneal Dialysis*/adverse effects
Amino Acids ; Humans ; Keto Acids ; Oxidative Stress ; Renal Dialysis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 1238

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